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Conserved domains on  [gi|1357062347|gb|PRL18748|]
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Dephospho-CoA kinase [Haemophilus influenzae]

Protein Classification

dephospho-CoA kinase( domain architecture ID 11112250)

dephospho-CoA kinase catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CoaE pfam01121
Dephospho-CoA kinase; This family catalyzes the phosphorylation of the 3'-hydroxyl group of ...
 19-197 2.96e-98

Dephospho-CoA kinase; This family catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form Coenzyme A EC:2.7.1.24. This enzyme uses ATP in its reaction.


:

Pssm-ID: 426062  Cd Length: 180  Bit Score: 283.44  E-value: 2.96e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  19 YIVGLTGGIGSGKTTIANLFADLGVPLVDADVVAREVVEKDSPLLSKIVEHFGTQILTDQGELNRAALREIVFHHDEEKQ 98
Cdd:pfam01121   1 LIVGLTGGIGSGKSTVANYFRDLGVPIIDADAIARQVVEPGGPALSRIVRHFGPTILDADGQLDRRALRELVFSNPERKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  99 WLNNLLHPAIRERMKQQLSEQTA-PYTLFVVPLLIENKLTALCDRILVVDVSPQTQLARSAQRDNNNFEQIQRIMNSQVS 177
Cdd:pfam01121  81 WLNGILHPLIRREIFKQIATLTAaPYVVLDIPLLFESGLHKLCHRVLVVDAPPELQVERLVARDGLSREEAQARIAAQAS 160

                         170       180
                  ....*....|....*....|
gi 1357062347 178 QQERLKWADDVINNDSDLAQ 197
Cdd:pfam01121 161 REERLALADDVLDNDGSLAE 180
 
Name Accession Description Interval E-value
CoaE pfam01121
Dephospho-CoA kinase; This family catalyzes the phosphorylation of the 3'-hydroxyl group of ...
 19-197 2.96e-98

Dephospho-CoA kinase; This family catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form Coenzyme A EC:2.7.1.24. This enzyme uses ATP in its reaction.


Pssm-ID: 426062  Cd Length: 180  Bit Score: 283.44  E-value: 2.96e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  19 YIVGLTGGIGSGKTTIANLFADLGVPLVDADVVAREVVEKDSPLLSKIVEHFGTQILTDQGELNRAALREIVFHHDEEKQ 98
Cdd:pfam01121   1 LIVGLTGGIGSGKSTVANYFRDLGVPIIDADAIARQVVEPGGPALSRIVRHFGPTILDADGQLDRRALRELVFSNPERKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  99 WLNNLLHPAIRERMKQQLSEQTA-PYTLFVVPLLIENKLTALCDRILVVDVSPQTQLARSAQRDNNNFEQIQRIMNSQVS 177
Cdd:pfam01121  81 WLNGILHPLIRREIFKQIATLTAaPYVVLDIPLLFESGLHKLCHRVLVVDAPPELQVERLVARDGLSREEAQARIAAQAS 160

                         170       180
                  ....*....|....*....|
gi 1357062347 178 QQERLKWADDVINNDSDLAQ 197
Cdd:pfam01121 161 REERLALADDVLDNDGSLAE 180
CoaE COG0237
Dephospho-CoA kinase [Coenzyme transport and metabolism]; Dephospho-CoA kinase is part of the ...
 19-213 8.79e-97

Dephospho-CoA kinase [Coenzyme transport and metabolism]; Dephospho-CoA kinase is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


Pssm-ID: 440007  Cd Length: 193  Bit Score: 280.03  E-value: 8.79e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  19 YIVGLTGGIGSGKTTIANLFADLGVPLVDADVVAREVVEKDSPLLSKIVEHFGTQILTDQGELNRAALREIVFHHDEEKQ 98
Cdd:COG0237     2 LIIGLTGGIGSGKSTVARMFAELGAPVIDADAIARELVEPGGPALAAIVEAFGEEILDADGSLDRKALAEIVFADPEALK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  99 WLNNLLHPAIRERMKQQLSEQ-TAPYTLFVVPLLIENKLTALCDRILVVDVSPQTQLARSAQRDNNNFEQIQRIMNSQVS 177
Cdd:COG0237    82 KLEAIVHPLVREEIERRLAAArGAPYVVLDIPLLFETGLEKLVDRVIVVDAPEEVQIERLMARDGLSEEEAEARIAAQMP 161

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1357062347 178 QQERLKWADDVINNDSDLAqnlpHLQKKVLELHQFY 213
Cdd:COG0237   162 DEEKRARADFVIDNDGSLE----ELRAQVDALLEKL 193
DPCK cd02022
Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of ...
 20-197 8.39e-87

Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis.


Pssm-ID: 238980  Cd Length: 179  Bit Score: 254.37  E-value: 8.39e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  20 IVGLTGGIGSGKTTIANLFADLGVPLVDADVVAREVVEKDSPLLSKIVEHFGTQILTDQGELNRAALREIVFHHDEEKQW 99
Cdd:cd02022     1 IIGLTGGIGSGKSTVAKLLKELGIPVIDADKIAHEVYEPGGPALQAIVEAFGPDILLEDGELDRKKLGEIVFADPEKRKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347 100 LNNLLHPAIRERMKQQLSE-QTAPYTLFVVPLLIENKLTALCDRILVVDVSPQTQLARSAQRDNNNFEQIQRIMNSQVSQ 178
Cdd:cd02022    81 LEAITHPLIRKEIEEQLAEaRKEKVVVLDIPLLFETGLEKLVDRVIVVDAPPEIQIERLMKRDGLSEEEAEARIASQMPL 160

                         170
                  ....*....|....*....
gi 1357062347 179 QERLKWADDVINNDSDLAQ 197
Cdd:cd02022   161 EEKRARADFVIDNSGSLEE 179
TIGR00152 TIGR00152
dephospho-CoA kinase; This model produces scores in the range of 0-25 bits against adenylate, ...
 20-208 4.90e-60

dephospho-CoA kinase; This model produces scores in the range of 0-25 bits against adenylate, guanylate, uridine, and thymidylate kinases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pantothenate and coenzyme A]


Pssm-ID: 272931  Cd Length: 190  Bit Score: 186.83  E-value: 4.90e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  20 IVGLTGGIGSGKTTIANLFADLG-VPLVDADVVAREVVEKDSPLLSKIVEHFGTQILTDQGELNRAALREIVFHHDEEKQ 98
Cdd:TIGR00152   1 LIALTGGIGSGKSTVLQYLADKYhFPVIDADKIAHQVVEPGQPAYHAIADHFGANILNQDGELDRKALGNYVFNDPEELK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  99 WLNNLLHPAIRERMKQQLSEQTAPYTLFV--VPLLIENKLTALCDRILVVDVSPQTQLARSAQRDNNNFEQIQRIMNSQV 176
Cdd:TIGR00152  81 WLNALTHPLIRQWMKKLIAQFQSKYALVLldVPLLFENNLRSLVDYVIVVERSPELQLERLMQRNDLTEEEVKKRLASQM 160

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1357062347 177 SQQERLKWADDVINNDSdlAQNLPHLQKKVLE 208
Cdd:TIGR00152 161 DIEEKLARIDTVIDNSG--PATLADLVKQLEE 190
PLN02422 PLN02422
dephospho-CoA kinase
 20-204 7.89e-47

dephospho-CoA kinase


Pssm-ID: 215232  Cd Length: 232  Bit Score: 154.52  E-value: 7.89e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  20 IVGLTGGIGSGKTTIANLFADLGVPLVDADVVAREVVEKDSPLLSKIVEHFGTQILTDQGELNRAALREIVFHHDEEKQW 99
Cdd:PLN02422    3 VVGLTGGIASGKSTVSNLFKSSGIPVVDADKVARDVLKKGSGGWKRVVAAFGEDILLPDGEVDREKLGQIVFSDPSKRQL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347 100 LNNLLHPAI-----RERMKQQLSeqTAPYTLFVVPLLIENKLTALCDRILVVDVSPQTQLARSAQRDNNNFEQIQRIMNS 174
Cdd:PLN02422   83 LNRLLAPYIssgifWEILKLWLK--GCKVIVLDIPLLFETKMDKWTKPVVVVWVDPETQLERLMARDGLSEEQARNRINA 160

                         170       180       190
                  ....*....|....*....|....*....|
gi 1357062347 175 QVSQQERLKWADDVINNDSDLAQNLPHLQK 204
Cdd:PLN02422  161 QMPLDWKRSKADIVIDNSGSLEDLKQQFQK 190
 
Name Accession Description Interval E-value
CoaE pfam01121
Dephospho-CoA kinase; This family catalyzes the phosphorylation of the 3'-hydroxyl group of ...
 19-197 2.96e-98

Dephospho-CoA kinase; This family catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form Coenzyme A EC:2.7.1.24. This enzyme uses ATP in its reaction.


Pssm-ID: 426062  Cd Length: 180  Bit Score: 283.44  E-value: 2.96e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  19 YIVGLTGGIGSGKTTIANLFADLGVPLVDADVVAREVVEKDSPLLSKIVEHFGTQILTDQGELNRAALREIVFHHDEEKQ 98
Cdd:pfam01121   1 LIVGLTGGIGSGKSTVANYFRDLGVPIIDADAIARQVVEPGGPALSRIVRHFGPTILDADGQLDRRALRELVFSNPERKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  99 WLNNLLHPAIRERMKQQLSEQTA-PYTLFVVPLLIENKLTALCDRILVVDVSPQTQLARSAQRDNNNFEQIQRIMNSQVS 177
Cdd:pfam01121  81 WLNGILHPLIRREIFKQIATLTAaPYVVLDIPLLFESGLHKLCHRVLVVDAPPELQVERLVARDGLSREEAQARIAAQAS 160

                         170       180
                  ....*....|....*....|
gi 1357062347 178 QQERLKWADDVINNDSDLAQ 197
Cdd:pfam01121 161 REERLALADDVLDNDGSLAE 180
CoaE COG0237
Dephospho-CoA kinase [Coenzyme transport and metabolism]; Dephospho-CoA kinase is part of the ...
 19-213 8.79e-97

Dephospho-CoA kinase [Coenzyme transport and metabolism]; Dephospho-CoA kinase is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


Pssm-ID: 440007  Cd Length: 193  Bit Score: 280.03  E-value: 8.79e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  19 YIVGLTGGIGSGKTTIANLFADLGVPLVDADVVAREVVEKDSPLLSKIVEHFGTQILTDQGELNRAALREIVFHHDEEKQ 98
Cdd:COG0237     2 LIIGLTGGIGSGKSTVARMFAELGAPVIDADAIARELVEPGGPALAAIVEAFGEEILDADGSLDRKALAEIVFADPEALK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  99 WLNNLLHPAIRERMKQQLSEQ-TAPYTLFVVPLLIENKLTALCDRILVVDVSPQTQLARSAQRDNNNFEQIQRIMNSQVS 177
Cdd:COG0237    82 KLEAIVHPLVREEIERRLAAArGAPYVVLDIPLLFETGLEKLVDRVIVVDAPEEVQIERLMARDGLSEEEAEARIAAQMP 161

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1357062347 178 QQERLKWADDVINNDSDLAqnlpHLQKKVLELHQFY 213
Cdd:COG0237   162 DEEKRARADFVIDNDGSLE----ELRAQVDALLEKL 193
DPCK cd02022
Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of ...
 20-197 8.39e-87

Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis.


Pssm-ID: 238980  Cd Length: 179  Bit Score: 254.37  E-value: 8.39e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  20 IVGLTGGIGSGKTTIANLFADLGVPLVDADVVAREVVEKDSPLLSKIVEHFGTQILTDQGELNRAALREIVFHHDEEKQW 99
Cdd:cd02022     1 IIGLTGGIGSGKSTVAKLLKELGIPVIDADKIAHEVYEPGGPALQAIVEAFGPDILLEDGELDRKKLGEIVFADPEKRKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347 100 LNNLLHPAIRERMKQQLSE-QTAPYTLFVVPLLIENKLTALCDRILVVDVSPQTQLARSAQRDNNNFEQIQRIMNSQVSQ 178
Cdd:cd02022    81 LEAITHPLIRKEIEEQLAEaRKEKVVVLDIPLLFETGLEKLVDRVIVVDAPPEIQIERLMKRDGLSEEEAEARIASQMPL 160

                         170
                  ....*....|....*....
gi 1357062347 179 QERLKWADDVINNDSDLAQ 197
Cdd:cd02022   161 EEKRARADFVIDNSGSLEE 179
TIGR00152 TIGR00152
dephospho-CoA kinase; This model produces scores in the range of 0-25 bits against adenylate, ...
 20-208 4.90e-60

dephospho-CoA kinase; This model produces scores in the range of 0-25 bits against adenylate, guanylate, uridine, and thymidylate kinases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pantothenate and coenzyme A]


Pssm-ID: 272931  Cd Length: 190  Bit Score: 186.83  E-value: 4.90e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  20 IVGLTGGIGSGKTTIANLFADLG-VPLVDADVVAREVVEKDSPLLSKIVEHFGTQILTDQGELNRAALREIVFHHDEEKQ 98
Cdd:TIGR00152   1 LIALTGGIGSGKSTVLQYLADKYhFPVIDADKIAHQVVEPGQPAYHAIADHFGANILNQDGELDRKALGNYVFNDPEELK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  99 WLNNLLHPAIRERMKQQLSEQTAPYTLFV--VPLLIENKLTALCDRILVVDVSPQTQLARSAQRDNNNFEQIQRIMNSQV 176
Cdd:TIGR00152  81 WLNALTHPLIRQWMKKLIAQFQSKYALVLldVPLLFENNLRSLVDYVIVVERSPELQLERLMQRNDLTEEEVKKRLASQM 160

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1357062347 177 SQQERLKWADDVINNDSdlAQNLPHLQKKVLE 208
Cdd:TIGR00152 161 DIEEKLARIDTVIDNSG--PATLADLVKQLEE 190
PLN02422 PLN02422
dephospho-CoA kinase
 20-204 7.89e-47

dephospho-CoA kinase


Pssm-ID: 215232  Cd Length: 232  Bit Score: 154.52  E-value: 7.89e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  20 IVGLTGGIGSGKTTIANLFADLGVPLVDADVVAREVVEKDSPLLSKIVEHFGTQILTDQGELNRAALREIVFHHDEEKQW 99
Cdd:PLN02422    3 VVGLTGGIASGKSTVSNLFKSSGIPVVDADKVARDVLKKGSGGWKRVVAAFGEDILLPDGEVDREKLGQIVFSDPSKRQL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347 100 LNNLLHPAI-----RERMKQQLSeqTAPYTLFVVPLLIENKLTALCDRILVVDVSPQTQLARSAQRDNNNFEQIQRIMNS 174
Cdd:PLN02422   83 LNRLLAPYIssgifWEILKLWLK--GCKVIVLDIPLLFETKMDKWTKPVVVVWVDPETQLERLMARDGLSEEQARNRINA 160

                         170       180       190
                  ....*....|....*....|....*....|
gi 1357062347 175 QVSQQERLKWADDVINNDSDLAQNLPHLQK 204
Cdd:PLN02422  161 QMPLDWKRSKADIVIDNSGSLEDLKQQFQK 190
coaE PRK03333
dephospho-CoA kinase/protein folding accessory domain-containing protein; Provisional
 21-197 9.15e-42

dephospho-CoA kinase/protein folding accessory domain-containing protein; Provisional


Pssm-ID: 179560 [Multi-domain]  Cd Length: 395  Bit Score: 145.53  E-value: 9.15e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  21 VGLTGGIGSGKTTIANLFADLGVPLVDADVVAREVVEKDSPLLSKIVEHFGTQILTDQGELNRAALREIVFHHDEEKQWL 100
Cdd:PRK03333    4 IGLTGGIGAGKSTVAARLAELGAVVVDADVLAREVVEPGTEGLAALVAAFGDDILLADGALDRPALAAKAFADDEARAVL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347 101 NNLLHPAIRERmKQQLSEQTAPYTLFV--VPLLIENKLTALCDRILVVDVSPQTQLARSAQRDNNNFEQIQRIMNSQVSQ 178
Cdd:PRK03333   84 NGIVHPLVGAR-RAELIAAAPEDAVVVedIPLLVESGMAPLFHLVVVVDADVEVRVRRLVEQRGMAEADARARIAAQASD 162

                         170
                  ....*....|....*....
gi 1357062347 179 QERLKWADDVINNDSDLAQ 197
Cdd:PRK03333  163 EQRRAVADVWLDNSGTPDE 181
coaE PRK14734
dephospho-CoA kinase; Provisional
 21-197 7.57e-41

dephospho-CoA kinase; Provisional


Pssm-ID: 237808  Cd Length: 200  Bit Score: 138.05  E-value: 7.57e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  21 VGLTGGIGSGKTTIANLFADLGVPLVDADVVAREVVEKDSPLLSKIVEHFGTQILTDQGELNRAALREIVFHHDEEKQWL 100
Cdd:PRK14734    4 IGLTGGIGSGKSTVADLLSSEGFLIVDADQVARDIVEPGQPALAELAEAFGDDILNPDGTLDRAGLAAKAFASPEQTALL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347 101 NNLLHPAIRERMKQQLSE---QTAPYTLFVVPLLIENKLTALCDRILVVDVSPQTQLARSAQRDNNNFEQIQRIMNSQVS 177
Cdd:PRK14734   84 NAITHPRIAEETARRFNEaraQGAKVAVYDMPLLVEKGLDRKMDLVVVVDVDVEERVRRLVEKRGLDEDDARRRIAAQIP 163

                         170       180
                  ....*....|....*....|
gi 1357062347 178 QQERLKWADDVINNDSDLAQ 197
Cdd:PRK14734  164 DDVRLKAADIVVDNNGTREQ 183
PTZ00451 PTZ00451
dephospho-CoA kinase; Provisional
 20-220 1.45e-26

dephospho-CoA kinase; Provisional


Pssm-ID: 185630  Cd Length: 244  Bit Score: 102.26  E-value: 1.45e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  20 IVGLTGGIGSGKTTIANLFAD-LGVPLVDADVVAREVVEKDSPLLSKIVEHFGTQILTDQGELNRAALREIVFHHDEEKQ 98
Cdd:PTZ00451    3 LIGLTGGIACGKSTVSRILREeHHIEVIDADLVVRELQAPNMACTRKIAARWPLCVHPETGELNRAELGKIIFSDAQARR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  99 WLNNLLHPAI------------RERMKQQLSEQTAPYTLFVVPLLIENKL-TALCDRILVVDVSPQTQLARSAQRDNNNF 165
Cdd:PTZ00451   83 ALGRIMNPPIfrailkriaaawWEDLWRSGAGSSPLIVVLDAPTLFETKTfTYFVSASVVVSCSEERQIERLRKRNGFSK 162

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1357062347 166 EQ-IQRImNSQVSQQERLKWADDVINNDSdlAQNLPHLQKKVLELHQFYLQQAENK 220
Cdd:PTZ00451  163 EEaLQRI-GSQMPLEEKRRLADYIIENDS--ADDLDELRGSVCDCVAWMSRQSNKR 215
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
 20-192 1.26e-04

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 40.88  E-value: 1.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  20 IVgLTGGIGSGKTTIANLFAD-LGVPLVDADVVarevvekdspllskIVEHFG---TQILTDQGElnrAALREIvfhhde 95
Cdd:COG0703     1 IV-LIGMMGAGKSTVGRLLAKrLGLPFVDTDAE--------------IEERAGmsiPEIFAEEGE---AGFREL------ 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  96 EKQWLNNLL---------------HPAIRERMKQqlseqtapytlfvvpllienkltalcdRILVV--DVSPQTQLARSA 158
Cdd:COG0703    57 EREVLAELLeeenaviatgggavlSPENRELLKE---------------------------HGTVVylDASPETLLERLR 109

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1357062347 159 QRDN-------NNFEQIQRIMnsqvsqQERL----KWADDVINND 192
Cdd:COG0703   110 RDDNrpllqgeDPRERLEELL------AEREplyrEVADITVDTD 148
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 23-192 3.01e-04

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 39.85  E-value: 3.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  23 LTGGIGSGKTTIANLFAD-LGVPLVDADVVarevvekdspllskIVEHFGTQIltdqgelnraalREIVFHHDEEkqwln 101
Cdd:cd00464     4 LIGMMGAGKTTVGRLLAKaLGLPFVDLDEL--------------IEQRAGMSI------------PEIFAEEGEE----- 52

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347 102 nllhpAIRERMKQQLSEQTAPYTLFV-----VPLLIENKLTALCDRILV-VDVSPQTQLAR---SAQR---DNNNFEQIQ 169
Cdd:cd00464    53 -----GFRELEREVLLLLLTKENAVIatgggAVLREENRRLLLENGIVVwLDASPEELLERlarDKTRpllQDEDPERLR 127

                         170       180
                  ....*....|....*....|....*..
gi 1357062347 170 RIMNsqvsqqERL----KWADDVINND 192
Cdd:cd00464   128 ELLE------EREplyrEVADLTIDTD 148
AAA_17 pfam13207
AAA domain;
24-169 5.02e-04

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 38.76  E-value: 5.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  24 TGGIGSGKTTIANLFA-DLGVPLVDA-DVVAREVVEKDsplLSKIVEHFGTQILTDQGELNRAALREIVfHHDEEKqwlN 101
Cdd:pfam13207   1 TGVPGSGKTTQLKKLAeKLGFPHISAgDLLREEAKERG---LVEDRDEMRKLPLEPQKELQKLAAERIA-EEAGEG---G 73

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1357062347 102 NLL--HPAIRErMKQQLSEqtapytlfvVPLLIENKLTAlcDRILVVDVSPQT-----QLARSAQRDNNNFEQIQ 169
Cdd:pfam13207  74 VIVdgHPRIKT-PAGYLPG---------LPVEVLRELKP--DAIILLEADPEEilerrLKDRTRGRDDDSEEEIR 136
GntK COG3265
Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the ...
 16-49 1.34e-03

Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442496 [Multi-domain]  Cd Length: 164  Bit Score: 38.19  E-value: 1.34e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1357062347  16 HMSYIV-GLTGgigSGKTTIANLFAD-LGVPLVDAD 49
Cdd:COG3265     1 PMVIVVmGVSG---SGKSTVGQALAErLGWPFIDGD 33
aroK PRK00131
shikimate kinase; Reviewed
 15-115 1.41e-03

shikimate kinase; Reviewed


Pssm-ID: 234654 [Multi-domain]  Cd Length: 175  Bit Score: 38.25  E-value: 1.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357062347  15 NHMSYIVgLTGGIGSGKTTIANLFAD-LGVPLVDADVVarevvekdspllskIVEHFGT---QILTDQGElnrAALREIv 90
Cdd:PRK00131    2 LKGPNIV-LIGFMGAGKSTIGRLLAKrLGYDFIDTDHL--------------IEARAGKsipEIFEEEGE---AAFREL- 62

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1357062347  91 fhhdeEKQWLNNL---------------LHPAIRERMKQQ 115
Cdd:PRK00131   63 -----EEEVLAELlarhnlvistgggavLREENRALLRER 97
Fap7 COG1936
Broad-specificity NMP kinase [Nucleotide transport and metabolism];
20-67 1.89e-03

Broad-specificity NMP kinase [Nucleotide transport and metabolism];


Pssm-ID: 441539 [Multi-domain]  Cd Length: 173  Bit Score: 37.87  E-value: 1.89e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1357062347  20 IVGLTGGIGSGKTTIANLFAD-LGVPLVDA-DVVARE--VVEKDSPLLSKIV 67
Cdd:COG1936     2 RIAITGTPGTGKTTVAKLLAErLGLEVIHLnDLVKEEglYTEVDEERDSLVV 53
NK cd02019
Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of ...
 20-41 2.31e-03

Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates to nucleosides/nucleotides, nucleoside monophosphates, or sugars. Members of this family play a wide variety of essential roles in nucleotide metabolism, the biosynthesis of coenzymes and aromatic compounds, as well as the metabolism of sugar and sulfate.


Pssm-ID: 238977 [Multi-domain]  Cd Length: 69  Bit Score: 35.39  E-value: 2.31e-03
                          10        20
                  ....*....|....*....|..
gi 1357062347  20 IVGLTGGIGSGKTTIANLFADL 41
Cdd:cd02019     1 IIAITGGSGSGKSTVAKKLAEQ 22
PRK05480 PRK05480
uridine/cytidine kinase; Provisional
 13-36 2.42e-03

uridine/cytidine kinase; Provisional


Pssm-ID: 235492 [Multi-domain]  Cd Length: 209  Bit Score: 37.83  E-value: 2.42e-03
                          10        20
                  ....*....|....*....|....
gi 1357062347  13 MGNHMSYIVGLTGGIGSGKTTIAN 36
Cdd:PRK05480    1 MMMKKPIIIGIAGGSGSGKTTVAS 24
PRK13949 PRK13949
shikimate kinase; Provisional
 23-89 8.55e-03

shikimate kinase; Provisional


Pssm-ID: 140006 [Multi-domain]  Cd Length: 169  Bit Score: 35.86  E-value: 8.55e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1357062347  23 LTGGIGSGKTTIANLFAD-LGVPLVDADVVAREVVEKDSpllskivehfgTQILTDQGElnrAALREI 89
Cdd:PRK13949    6 LVGYMGAGKTTLGKALAReLGLSFIDLDFFIENRFHKTV-----------GDIFAERGE---AVFREL 59
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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