|
Name |
Accession |
Description |
Interval |
E-value |
| MATE_NorM_like |
cd13131 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio ... |
11-441 |
5.22e-137 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Vibrio cholerae NorM and functions most likely as a multidrug efflux pump, removing xenobiotics from the interior of the cell. The pump utilizes a cation gradient across the membrane to facilitate the export process. NorM appears to bind monovalent cations in an outward-facing conformation and may subsequently cycle through an inward-facing and outward-facing conformation to capture and release its substrate.
Pssm-ID: 240536 [Multi-domain] Cd Length: 435 Bit Score: 400.34 E-value: 5.22e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 11 KRNLRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRLL 90
Cdd:cd13131 3 RALLRLALPILIAQLAQMAMGFVDTVMAGRLGADDLAAVALGSSLWFPVFTFGMGLLLAVTPLVAQAHGAGDRRRIRRAV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 91 ENSLSLNTIASVILALLMFAMSFFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIANA 170
Cdd:cd13131 83 RQGLWLALLLSLPLMLLLWLAPPILPLMGQEPEVAAIARGYLLALAWGIPPALLFQVLRSFLDALGRTRPAMVITLLALV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 171 LNIFLNWILIYGHLGFEAMGVQGAALATLISRILMFLSFLYLIFRHSAYNKYLVYFSKKFFDPKIVREVLKTSIPLSFQN 250
Cdd:cd13131 163 LNIPLNYVLIFGKFGLPALGGAGAGLATAIVYWLMFLALAFYIRRHKRFRRYRLFARFWRPDWARLKELLRLGLPIGLTI 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 251 LVEITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVALMSVS 330
Cdd:cd13131 243 FFEVSLFAAVALLMGRLGTTVLAAHQIALNFASLLFMVPLGISMAATVRVGFALGAGDPADARRAGLVGLGLGVGFAALT 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 331 GLAYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISYYLVCLPLGYFCGVY 410
Cdd:cd13131 323 ALLLLLFPEQIAGLYTNDPAVIALAASLLVFAALFQLFDGIQVVAAGALRGYKDTRVPFLLALISYWGIGLPLGYLLAFT 402
|
410 420 430
....*....|....*....|....*....|.
gi 1309054203 411 LEMGAVGVWIGLLLGLVFAALLFLWRFDKIS 441
Cdd:cd13131 403 TGLGAFGVWIGLIIGLALAAILLLWRFRRLQ 433
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
8-436 |
7.84e-103 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 312.85 E-value: 7.84e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 8 PYYKRNLRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVG 87
Cdd:COG0534 5 PILKLLLRLALPIILGNLLQSLYGLVDTIFVGRLGTAALAAVGLAFPIFFLLIALGIGLGVGGTALVAQALGAGDREEAR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 88 RLLENSLSLNTIASVILALLMFAMS-FFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITL 166
Cdd:COG0534 85 RVLGQALLLALLLGLLLTLLGLLFApPLLRLLGADPEVLALARDYLRIILLGLPFLLLFNVLNGILRGLGDTKTPMIIML 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 167 IANALNIFLNWILIYGHlgfeAMGVQGAALATLISRILMFLSFLYLIFRHSAYNKYlvYFSKKFFDPKIVREVLKTSIPL 246
Cdd:COG0534 165 IGNVLNIVLDPLLIFGG----GLGVAGAALATVISQAVSALLLLYYLFRKRSLLRL--RLRDLRPDRKILKRILRIGLPA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 247 SFQNLVEITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVAL 326
Cdd:COG0534 239 GLQQLAESLGFLVLNALVARLGTAAVAAYGIALRIESLAFMPALGLGQAAQPLVGQNLGAGDYDRARRAARLALLLALGI 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 327 MSVSGLAYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISYYLVCLPLGYF 406
Cdd:COG0534 319 GLLLALLLFLFPEPIIGLFTDDPEVIALAATYLRIAALFQPFDGLQFVLSGALRGAGDTRFPMIISLLRLWLVRLPLAYL 398
|
410 420 430
....*....|....*....|....*....|
gi 1309054203 407 cGVYLEMGAVGVWIGLLLGLVFAALLFLWR 436
Cdd:COG0534 399 -LAFLGLGLTGVWLALPIGEVLRALLLLLR 427
|
|
| PRK01766 |
PRK01766 |
multidrug efflux protein; Reviewed |
11-447 |
1.08e-101 |
|
multidrug efflux protein; Reviewed
Pssm-ID: 234981 [Multi-domain] Cd Length: 456 Bit Score: 310.98 E-value: 1.08e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 11 KRNLRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRLL 90
Cdd:PRK01766 12 RQLLALALPILLAQVAQTAMGFVDTVMAGGVSATDLAAVAIGTSIWLPVILFGHGLLLALTPIVAQLNGAGRRERIAHQV 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 91 ENSLSLNTIASVILALLMF-AMSFFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIAN 169
Cdd:PRK01766 92 RQGLWLALFLSVLIMLVLYnAVPPILNMMNLEPEVADIAVGYLHALLWGIPAYLLYQVLRSFIDGLGKTKPTMVIGFLGL 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 170 ALNIFLNWILIYGHLGFEAMGVQGAALATLISRILMFLSFLYLIFRHSAYNKYLVYfsKKF--FDPKIVREVLKTSIPLS 247
Cdd:PRK01766 172 LINIPLNYIFIYGKFGFPELGGVGCGVATAIVYWVMFLAMLIYIKRARRFRDFRLF--KGLykPDWAVIKRLLKLGLPIG 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 248 FQNLVEITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVALM 327
Cdd:PRK01766 250 LAIFFEVSLFAVVTLLVSPLGTVTVAAHQIALNFSSLLFMLPLSLAMALTIRVGFELGAGRTLDARQYAYIGLAVGLGMA 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 328 SVSGLAYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISYYLVCLPLGYFC 407
Cdd:PRK01766 330 LLTAIFLVLFREQIALLYTDDPEVVALASHLLLFAALFQFSDAIQVIGSGALRGYKDTRVIFFITFIAYWVLGLPLGYIL 409
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 1309054203 408 GVYLEMGAVGVWIGLLLGLVFAALLFLWRFDKISNQIINS 447
Cdd:PRK01766 410 ALTDPMGPFGFWIGLIIGLTAAAILLLLRLRKLQRQPSAI 449
|
|
| MATE_like_7 |
cd13133 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
10-437 |
6.18e-85 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240538 [Multi-domain] Cd Length: 438 Bit Score: 267.09 E-value: 6.18e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 10 YKRNLRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRL 89
Cdd:cd13133 4 YREILKIALPLVLSMLSQTVMGFTDRAFLGRLSEVALAASGPAGVLYFAILMLFFGLSSGVQVFVAQYNGAGRYSRIGRV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 90 LENSLSLNTIASVILALLM-FAMSFFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIA 168
Cdd:cd13133 84 LWQGLYFSLLLAPLLALLSaLAAPLLFLLLGHSPEVQALEVEYFRIRILGAPFSLLGAALRAFFSGIGRTRVVMVANLVM 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 169 NALNIFLNWILIYGHLGFEAMGVQGAALATLISRILMFLSFLYLIFRHSAYNKYLVYFSKKfFDPKIVREVLKTSIPLSF 248
Cdd:cd13133 164 VVVNIVLDYALIFGKLGFPAMGIAGAAIATVIAEAVSLLFFLLLLFRRKNRRRFGLRRAWR-FDRELLRRILRLGLPSGL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 249 QNLVEITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVALMS 328
Cdd:cd13133 243 QFFLDVGAFTVFFLLIGRLGTTELAATNIVFSINSLAFLPMIGLGIAVSSLVGQALGAGRPDLAMRVTRRGLKLALAYML 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 329 VSGLAYILFRNYIPMIYTEDV---LVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISYYLVCLPLGY 405
Cdd:cd13133 323 LLGILFLLFPELLLSIFTPGAdfaLIAELAVPLLRFVAAYILFDALALVFAGALRGAGDTRFVMLAELIVAWLYLLPPAY 402
|
410 420 430
....*....|....*....|....*....|..
gi 1309054203 406 FcGVYLEMGAVGVWIGLLLGLVFAALLFLWRF 437
Cdd:cd13133 403 L-LVVLGAGLAGAWTVETVYVIVLALIFLLRF 433
|
|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
11-439 |
2.75e-84 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 265.14 E-value: 2.75e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 11 KRNLRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRLL 90
Cdd:cd13137 1 RRIWSLAWPVILENLLQTLVGLVDVFMVGRLGAEAIAAVGLATQVLWLLLVLNMALGTGTVALVSQSYGAGDYERARRAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 91 ENSLSLNTIASVILALLMFAMS-FFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIAN 169
Cdd:cd13137 81 GQSLLLALLLSLPLALLGLLFAePLLRLLGADPEVIALALTYLRIVLLGIPFFFLSLVGNAALRGAGDTKTPMYIMIIVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 170 ALNIFLNWILIYGHLGFEAMGVQGAALATLISRILMFLSFLYLIFRHSayNKYLVYFSKKFFDPKIVREVLKTSIPLSFQ 249
Cdd:cd13137 161 VLNIVLDYVLIFGLWGFPGLGVAGAALATVISRVVGALLLLFLLLRGR--LPIKISFKGFRLDRKIIKKLLRIGLPAGLE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 250 NLVEITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVALMSV 329
Cdd:cd13137 239 QLLRSLGFLVLLAIVASYGTAALAAYQIGLRIESLAFMPGFGFSMAASTLVGQNLGAGDPDEARRYGKRALRLGVLFMGL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 330 SGLAYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISYYLVCLPLGYFCGV 409
Cdd:cd13137 319 LGLLLFIFAPPLASLFTPDPEVIELGVLYLRIVALSQPFLAISFVLSGALRGAGDTRPPLIINLISMWLVRLPLAYLLGF 398
|
410 420 430
....*....|....*....|....*....|
gi 1309054203 410 YLEMGAVGVWIGLLLGLVFAALLFLWRFDK 439
Cdd:cd13137 399 VLGLGLTGIWLAMFVDTIVRAILLLYRFRK 428
|
|
| MATE_eukaryotic |
cd13132 |
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral ... |
10-435 |
4.58e-79 |
|
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. This subfamily, which is restricted to eukaryotes, contains vertebrate solute transporters responsible for secretion of cationic drugs across the brush border membranes, yeast proteins located in the vacuole membrane, and plant proteins involved in disease resistance and iron homeostatis under osmotic stress.
Pssm-ID: 240537 [Multi-domain] Cd Length: 436 Bit Score: 251.72 E-value: 4.58e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 10 YKRNLRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIF-ILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGR 88
Cdd:cd13132 2 AKKLLRLAAPLVLTSLLQYSLSVVSVVFVGHLGKLELAAASLASSFAnVTGFSILLGLASALDTLCGQAFGAKNYKLVGV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 89 LLENSLSLNTIASVILALLMFAMSFFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIA 168
Cdd:cd13132 82 YLQRALVILLLCCVPISLLWLNTEPILLLLGQDPEIARLAGEYLRWLIPGLFAYALFEPLKRYLQAQGIVLPLVYISLVA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 169 NALNIFLNWILIYGHlgfeAMGVQGAALATLISRILMFLSFLYLIFRHSAYNKYLVYFSKKFFDPkiVREVLKTSIPLSF 248
Cdd:cd13132 162 LLLNILLNYLLVFVL----GLGFIGAALATSISYWLIVVLLLLYIFFSKGHKATWGGFSREAFRG--WGPFLKLAIPSAL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 249 QNLVEITAFSLSAIMVGW-SGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVALM 327
Cdd:cd13132 236 MLCLEWWAFEILVLLAGLlPGTVALAAQSICLTTTSLLYMIPLGISIAASVRVGNELGAGNPKRAKLAAIVALILSLVIG 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 328 SVSGLAYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISYYLVCLPLGYFC 407
Cdd:cd13132 316 VVVAILLLVLRDVWAYLFTSDEEVIALVADLLPILALFQIFDGLQAVLSGVLRGCGRQKLGAYVNLVAYYLIGLPVGLLL 395
|
410 420
....*....|....*....|....*...
gi 1309054203 408 GVYLEMGAVGVWIGLLLGLVFAALLFLW 435
Cdd:cd13132 396 AFVLGLGLKGLWIGLIAGLILQAVILLL 423
|
|
| MATE_like_8 |
cd13134 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
14-437 |
9.83e-78 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240539 [Multi-domain] Cd Length: 438 Bit Score: 248.57 E-value: 9.83e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 14 LRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRLLENS 93
Cdd:cd13134 6 FALAWPIFIELLLQMLLGTIDTFMLSRYSDNAVAAVGVANQILFLLILIFSFISTGTSILIAQYLGAKDKKKARQIAGVA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 94 LSLNTIASVILALL-MFAMSFFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIANALN 172
Cdd:cd13134 86 LLFNLLLGLVFSLLlLFFGAELLRLMGLPPELLALGSTYLRIVGGSLFLQALSLTLSAILRSHGRTKIPMYVSLIMNILN 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 173 IFLNWILIYGHLGFEAMGVQGAALATLISRILMFLSFLYLIFRHSAYNKYLVYFSKkfFDPKIVREVLKTSIPLSFQNLV 252
Cdd:cd13134 166 IVGNYLLIFGWFGLPKLGVAGVAISTVISRAVGLVLLFILLFRKLKIRFRLKDLRP--FPKKLLKKILKIGLPSAGEELS 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 253 EITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVALMSVSGL 332
Cdd:cd13134 244 YNLSQTVITAFIARLGTAALAARTYASNISMFVFLFSLAIGQATQIIVGHLVGAGDFDEAYKRVLKSLKIGLLVSLAVAL 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 333 AYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISYYLVCLPLGYFCGVYLE 412
Cdd:cd13134 324 LLALFREPILGLFTDDPEIIALGKTLLLISILLEPGRAFNIVLIGSLRAAGDARFPVLIGIISMWGISVPLAYLLGIVLG 403
|
410 420
....*....|....*....|....*
gi 1309054203 413 MGAVGVWIGLLLGLVFAALLFLWRF 437
Cdd:cd13134 404 LGLLGVWIAFAADEWVRGIIMLWRW 428
|
|
| matE |
TIGR00797 |
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A. ... |
19-363 |
3.61e-68 |
|
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS. [Transport and binding proteins, Other]
Pssm-ID: 273273 [Multi-domain] Cd Length: 342 Bit Score: 220.58 E-value: 3.61e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 19 PVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRLLENSLSLNT 98
Cdd:TIGR00797 1 PAILANILQPLLGLVDTAFVGHLGPVDLAAVSLGSSVFMFLFSILMGLGTATTALVAQAVGAGNYQRLGRQAQQSLLLAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 99 IASV-ILALLMFAMSFFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIANALNIFLNW 177
Cdd:TIGR00797 81 LLGLpVLLVGYFFIDPLLSLMGADGEVAELAQDYLRILILGIPAYLLNFVLRGFLRGQGDTKTPMYITLIGNVINIILNY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 178 ILIYGHLGFeaMGVQGAALATLISRILMFLSFLYLIFRHSAYnkYLVYFSKKFFDPKIVREVLKTSIPLSFQNLVEITAF 257
Cdd:TIGR00797 161 ILIFGKFGF--LGIVGAALATVISYWLMFLLLLYYIKKAKKI--GLKWEGLLKPDWEVLKRLLKLGLPIAFRVILESLSF 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 258 SLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVALMSVSGLAYILF 337
Cdd:TIGR00797 237 ALLALLVARLGSIALAAHQIALNVESLLFMPAFGFGIAVSILVGQALGAGDPKRAKEVARVALKLSLLLGLVLAIILILF 316
|
330 340
....*....|....*....|....*.
gi 1309054203 338 RNYIPMIYTEDVLVRELAAKLLVIAA 363
Cdd:TIGR00797 317 REFIARLFTNDPEVLELAAIYLIFVA 342
|
|
| MATE_like_12 |
cd13142 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
8-435 |
8.08e-63 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240547 [Multi-domain] Cd Length: 444 Bit Score: 209.74 E-value: 8.08e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 8 PYYKRNLRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVG 87
Cdd:cd13142 8 SILRTLLKLAWPIIVSNLLQVAYNLADTFWLGRLGADAVAAPSISWPLIFLFISLGGGLTVAGTALVAQYTGAGDYDKAN 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 88 RLLENSLSLNTIASVILALLMFAMS--FFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYIT 165
Cdd:cd13142 88 KVAGQTFSFVIILSLILAVLGYILSrpLLLLLIGAPEEVYPLALAYLRIIFLGLPFMFIFFVFNSLLRGIGDTKTPMKIM 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 166 LIANALNIFLNWILIYGHLGFEAMGVQGAALATLISRILMFLSFLYLIFRHSAYNKylVYFSKKFFDPKIVREVLKTSIP 245
Cdd:cd13142 168 FGSVLLNVILDPLLIFGIGPFPGLGVAGAALATVISRGIAAVIGLYLLFKGRVGLK--ISLRDLKPDWEWLKKIFRIGLP 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 246 LSFQNLVEITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVA 325
Cdd:cd13142 246 SSIEQSARALGFTVMTALVAGFGTVVVAAYGIGNRIISLVFLPAFGLARATSTMVGQNLGAGQIDRAEEIVKKAALLIFL 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 326 LMSVSGLAYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISYYLVCLPLGY 405
Cdd:cd13142 326 ILVIGGVLAFLFAEPIVRVFINDPEVIKEGADFLRIVAPSFPFFGLFQVINGAFRGSGHTLTAMIISILRLWVIRIPLAY 405
|
410 420 430
....*....|....*....|....*....|.
gi 1309054203 406 FCGVYLEMGAVGVWIGLLLGLVFAALL-FLW 435
Cdd:cd13142 406 LLAYVLGLGVTGIWIAMAISNIVAALIaLAW 436
|
|
| PRK00187 |
PRK00187 |
NorM family multidrug efflux MATE transporter; |
14-445 |
1.25e-56 |
|
NorM family multidrug efflux MATE transporter;
Pssm-ID: 166843 [Multi-domain] Cd Length: 464 Bit Score: 194.19 E-value: 1.25e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 14 LRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRLLENS 93
Cdd:PRK00187 13 LRLAGPLIASQLAHMLMVFTDTLMMGRLGPEALAGGGLGAASYSFVSIFCVGVIAAVGTLVAIRHGAGDIEGATRLAQAG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 94 LSLNTIASVILALLMFAMSFFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIANALNI 173
Cdd:PRK00187 93 LWLAWLLALVAALLLWNLKPLLLLFGQAPQNVDAAMQFLHLLPFALPGYLSFMALRGFTSALGRAGPVMVISLAGAVANL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 174 FLNWILIYGHLGFEAMGVQGAALATLISRILMFLSFLYLIFRHSAYNKYLVyfSKKFFDPK--IVREVLKTSIPLSFQNL 251
Cdd:PRK00187 173 LLNYALIEGWFGLPKLGLMGIGLVTALVSNGMALALALYIRRHPAYAAYPL--RKGLSRPSraALRELWRLGLPIGGTYA 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 252 VEITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVALMSVSG 331
Cdd:PRK00187 251 VEVGLFTFAALCMGALGSTQLAAHQIALQIVSVAFMVPVGLSYAVTMRVGQHYGAGRLLEARRAGRVGIGFGAVVMLLFA 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 332 LAYILFRNYIPMIYTE-----DVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISYYLVCLPLGYF 406
Cdd:PRK00187 331 GLFWLLPEAIIGLFLDrndpaFAEIVQLAVSLLAVAAWFELFDGTQTIAMGAIRGLKDARTTFLIGLACYWLVGAPLAWL 410
|
410 420 430
....*....|....*....|....*....|....*....
gi 1309054203 407 CGVYLEMGAVGVWIGLLLGLVFAALLFLWRFDKISNQII 445
Cdd:PRK00187 411 LAFTLGWGAVGVWWGLALGLACAAVALTLAFEWKTARLL 449
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
17-437 |
1.02e-54 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 187.92 E-value: 1.02e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 17 AIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRLLENSLSL 96
Cdd:cd12082 1 AAPLLLSMLLQTLYNLVDTFFLGRLLGDALAAVGLAFPLIALLIALGVGLSVGTSALISQAIGAGDEEKARRVLVQSIVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 97 NTIASVILALLM-FAMSFFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIANALNIFL 175
Cdd:cd12082 81 AILLGLLLAALLlFFSPLILSLLGAEEEVIELAATYLTILILGLPITFLGAVLSGILQGEGDTRTAMIISVLSNLLNILL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 176 NWILIYGhLGFEAMGVQGAALATLISRILMFLSFLYLIFRHsaYNKYLVYFSKKFFDPKIVREVLKTSIPLSFQN-LVEI 254
Cdd:cd12082 161 DPLLIFG-LGPPELGIAGAALATVISYVIGALLLLIYLRKG--KKILKFKLSLLKPDLELLRRLLRIGLPSAIQNsLLSL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 255 TAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVALMSVSGLAY 334
Cdd:cd12082 238 GLLIIVAIVAAFGGAAALAAYTVAFRIASLAFMPALGLAQAALPVVGQNLGAGNFDRARRITWVALLIGLLIGAVLGLLI 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 335 ILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISYYLVCLPLGYFcGVYLEMG 414
Cdd:cd12082 318 LLFPEPILSLFTNDPEFLELAVSYLRILAIYYLFVGIGYVLQAGFQAAGRTLKSLIVSLLSYWVVRLPLAYV-LAYLGLG 396
|
410 420
....*....|....*....|...
gi 1309054203 415 AVGVWIGLLLGLVFAALLFLWRF 437
Cdd:cd12082 397 LYGIWLALVISLILAALVLLLFF 419
|
|
| MATE_yoeA_like |
cd13138 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
14-435 |
1.52e-53 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240543 [Multi-domain] Cd Length: 431 Bit Score: 184.97 E-value: 1.52e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 14 LRVAIPVMLTQAGQITVNLADNIMVGH-LGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRLLEN 92
Cdd:cd13138 6 LLFALPLLLSNLLQQLYNLVDLLIVGQfLGVAALAAVSNGSPIIFLLTAIGMGLSMGGTILISQYIGAKDEEKAKKAVGT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 93 SLSLNTIASVILALLMFAMS-FFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIANAL 171
Cdd:cd13138 86 LLVLFLILGIVLTILGLLFApPILRLMNTPAEILELAVSYLRICFLGIPFIFGYNAYSAILRGLGDSKTPLYFVIIACVL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 172 NIFLNWILIYGhLGfeaMGVQGAALATLISRILMFLSFLYLIFRHsaynKYLVYFSKKFF--DPKIVREVLKTSIPLSFQ 249
Cdd:cd13138 166 NIILDLLFIAV-FH---MGVAGAALATVIAQAISVLLALYYLRKK----KLPFKLSLKDFrfDKEILKEILKIGLPSALQ 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 250 NLveITAFSLSAI--MVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVALM 327
Cdd:cd13138 238 QS--LVSISFLIInsIVNSYGVVASAAYGIANKINSFAFLPPSAIGQAVSTFVAQNIGAGKIERAKKGLRTGIIISLIIG 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 328 SVSGLAYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISYYLVCLPLGYFC 407
Cdd:cd13138 316 LIIILLVFFFAPQLLGLFTSDPEVIEIGAEYLRIYSIDYILFGILFVFNGLFRGLGKTKFPMIISILRLWLVRIPLAYLL 395
|
410 420
....*....|....*....|....*...
gi 1309054203 408 GVYLEMGAVGVWIGLLLGLVFAALLFLW 435
Cdd:cd13138 396 SRLTGLGLFGIWLAMPISNILSAIICII 423
|
|
| MATE_like_1 |
cd13140 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
14-437 |
2.86e-46 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240545 [Multi-domain] Cd Length: 435 Bit Score: 165.78 E-value: 2.86e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 14 LRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRLLENS 93
Cdd:cd13140 8 LRLALPIMGTSFIQMAYNLTDMFWVGRLGSDAVAAVGTAGFFVWLAYALALLSKIGAQVKVSQSIGAKDEKEARKYARNA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 94 LSLNTIASVILALLMFamsFFMDSMGQT-----PEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIA 168
Cdd:cd13140 88 LQLNLLLGILYGLLLL---LFAKPLIGFfnlgdAEVISLAITYLRIVALGLIFSFLNPVFTGIFNALGDSKTPFIINAIG 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 169 NALNIFLNWILIYGHLGFEAMGVQGAALATLISRILMFLSFLYLIFRHSAYNKYLVYFskKFFDPKIVREVLKTSIPLSF 248
Cdd:cd13140 165 LVLNIILDPLLIFGFGPFPALGVAGAALATVLAQAIVFLLFLYALKKKKGLFLKIRIL--KRPDRKYIKEILKLGLPVAL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 249 QNLVeITAFS--LSAIMVGWsGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVAL 326
Cdd:cd13140 243 QSIL-FALISmiLARIIASF-GPVAIAAQKVGSQIESISWMTAEGFSTALAAFVGQNYGAGKYDRIRKGYKTALKIASAI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 327 MSVSGLAYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISYYLVcLPLGYF 406
Cdd:cd13140 321 GLFATLLLFFFGEPLFSLFIPDPETIAIGVDYLRILGFSQLFMCLEITTTGAFNGLGRTKPPAIISIVFNGLR-IPLALL 399
|
410 420 430
....*....|....*....|....*....|.
gi 1309054203 407 CGVYLeMGAVGVWIGLLLGLVFAALLFLWRF 437
Cdd:cd13140 400 LSPTG-LGLNGIWWAISISSILKGIILTIWF 429
|
|
| MATE_like_14 |
cd13139 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
17-439 |
9.85e-43 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240544 [Multi-domain] Cd Length: 448 Bit Score: 156.23 E-value: 9.85e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 17 AIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRLLENSLSL 96
Cdd:cd13139 20 AIPMVLEMVMESLFAVVDLYFVSRLGALAIATVGLTESVLTIVYSIAIGLSMAATALVARRIGEKDPEGAGFAAVQAILL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 97 NTIASVILALLMFAM-SFFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIANALNIFL 175
Cdd:cd13139 100 GVALSLILSILGYFFaEDILSLMGASPAVIAEGYGYTRIMFGGNGFIMLLFLINGIFRGAGDAAIAMRSLWLANGLNIIL 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 176 NWILIYGHLGFEAMGVQGAALATLISRILMFLSFLYLIFRHSAYNKYLVYFSKkfFDPKIVREVLKTSIPLSFQNLVEIT 255
Cdd:cd13139 180 DPLFIFGLGPIPAMGVTGAAIATTIGRSIGVLYQLYHLFKGKGRIQIRRRHLK--LDWAIIKKIIKIAVGGILQFLIASS 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 256 AFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVALMSVSGLAYI 335
Cdd:cd13139 258 SWIFLVRIIAEFGSTALAGYTIAIRIIMFALLPAWGLSNAAATLVGQNLGAGQPDRAEKSVWRAGKYNMVFLGIVSLVFF 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 336 LFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISYYLVCLPLGYFCGVYLEMGA 415
Cdd:cd13139 338 LFAEPLVSFFTTDPEVIAIAVEALRIISLGYIFYGYGMVLSQAFNGAGDTKTPTLINLVGFWLFQIPLAYLLARHLNLGP 417
|
410 420
....*....|....*....|....
gi 1309054203 416 VGVWIGLLLGLVFAALLFLWRFDK 439
Cdd:cd13139 418 KGVFIAIPIAETVLAIAAIILFRR 441
|
|
| MATE_like_4 |
cd13144 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
14-437 |
8.63e-41 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240549 [Multi-domain] Cd Length: 434 Bit Score: 150.85 E-value: 8.63e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 14 LRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRLLENS 93
Cdd:cd13144 11 LTMSIPAMISMLFQALYNIVDSIFVARLGENALTAVSLAFPIQNLMIAVAVGTGVGVNALLSRSLGEKDQKEANKAANNG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 94 LSLNTIASVILALL-MFAMSFFMDSMGQTPEVVHQAKLYynTMLFSLFPFLMFFGL--RQFSEGIGITKYAMYITLIANA 170
Cdd:cd13144 91 LLLALLSYLLFLLLgLFGVKPFFRLFTDDPEILEYGYAY--LSWCVIFSFGMFFQIlcEKVLQSTGNTITPMIAQLIGAI 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 171 LNIFLNWILIYGHLGFEAMGVQGAALATLISRIL-MFLSFLYLIFRHSAYNKYLVYFSkkfFDPKIVREVLKTSIPLSFQ 249
Cdd:cd13144 169 INIILDPILIFGLFGFPAMGIAGAAIATVIGQILaMFLAFFFLLRKNKDVQPDLRLFR---PSLRIIKEIYAVGLPSIIM 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 250 NLV-EITAFSLSAIMVGWsGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVALMS 328
Cdd:cd13144 246 QAIsSVMVFGLNKILAGF-GPTAVAVFGIYFKLQSFVFMPVFGLNNGLIPIVAYNYGAGNKDRIREAIKYAILIAVVIML 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 329 VSGLAYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISYYLVCLPLGYFCG 408
Cdd:cd13144 325 AGGLLFQLFPDQLLGLFNASEEMLAIGVPALRIISLSFLFAALSIILSGLFQALGRGVYSLIISVARQLVVLLPLAWLLA 404
|
410 420 430
....*....|....*....|....*....|..
gi 1309054203 409 VYLemGAVGVWIGLLLGLVFA---ALLFLWRF 437
Cdd:cd13144 405 KMF--GLNGVWWSFPIAEIVSfllSLLFLKRL 434
|
|
| MATE_DinF_like |
cd13136 |
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE) ... |
10-437 |
1.02e-39 |
|
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240541 [Multi-domain] Cd Length: 424 Bit Score: 147.71 E-value: 1.02e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 10 YKRNLRVAIPVMLTQAGQITVNLADNIMVGHLGTA-ELAGVSFANSIFILgMVFGIGFTQ-GLTPHVGQSFGKGDQAKVG 87
Cdd:cd13136 2 HREILALALPAILSNITVPLLGLVDTAVVGHLGSAaYLGAVALGTTIFNT-LFWLFGFLRmGTTGLVAQALGAGDREEAI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 88 RLLENSLSLNTIASVILALLMF-AMSFFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITL 166
Cdd:cd13136 81 ALLVRALLLALAIGLLLILLQSpLLALALLLLGASAAVAALARQYLRIRILGAPAVLLNYVATGWFRGLQDTRTPLILQI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 167 IANALNIFLNWILIYGHlgfeAMGVQGAALATLISRILMFLSFLYLIFRHsaYNKYLVYFSKKFFDPKIVREVLKTSIPL 246
Cdd:cd13136 161 VGNVVNIVLDPLFVFGL----GWGVAGAALATVIAQYLGALLGLWLLRRR--VRLLGKSLSRRLPSKAALKRLFKLNRDI 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 247 SFQNLVEITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVAL 326
Cdd:cd13136 235 FIRTLALLAAFLFFTALAARLGDVILAANQILLQFWLLSSYFLDGFAYAAEALVGRALGAGDRKAARRVARRLLQWGLGL 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 327 MSVSGLAYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAI--QLSG-LAALRALADVKIPLILSIISYYLVCLPL 403
Cdd:cd13136 315 GVLLALLFFLGGEPIIRLFTDDPAVLALAATYLPWLALLPPIGALafVLDGiFIGATDTRYLRNSMLVSLAVFLPLLFLL 394
|
410 420 430
....*....|....*....|....*....|....
gi 1309054203 404 GYFcgvyleMGAVGVWIGLLLGLVFAALLFLWRF 437
Cdd:cd13136 395 VPL------WGNHGLWLALILFMLLRGLTLALRL 422
|
|
| MATE_MepA_like |
cd13143 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
14-432 |
7.61e-38 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.
Pssm-ID: 240548 [Multi-domain] Cd Length: 426 Bit Score: 142.65 E-value: 7.61e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 14 LRVAIPVMLTQAGQITVNLADNIMVGHL-GTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRLLEN 92
Cdd:cd13143 7 LKFALPAIIGMLVNGLYNIVDGIFVGHGvGALALAAVNLVFPIIMLLMALGLMIGVGGASLISRRLGAGDREKANRIFST 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 93 SLSLNTIASVILALLMFamsFFMDS----MGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIA 168
Cdd:cd13143 87 ALLLSLILGLLLTILGL---LFLDPllrlLGASGELLPYAVDYLRIILLGAPFTILSSVLNNLLRAEGKPKLAMLGMLIG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 169 NALNIFLNWILIyghLGFEaMGVQGAALATLISRILMFLsfLYLIFRHSAYNKYLVYFSKKFFDPKIVREVLKTSIPLSF 248
Cdd:cd13143 164 AVLNIILDPLFI---FVLG-LGIAGAALATVIAQLISLL--LLLLYFFRGKSLLKLSLLRFKLSLKIIKEILALGFPSFL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 249 QNL-VEITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVALM 327
Cdd:cd13143 238 MQLsSSVVTIVLNLTLLGYGGDIGVAAFGIVTRILTFLFLPLIGLSQGLQPIIGYNYGAGNYDRVKQALKLALIVALIYG 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 328 SVSGLAYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISYYLVCLPLGYFC 407
Cdd:cd13143 318 LVLFLILLLFPEQIVSLFTDDPELIALAARILRIFLLAFPLAGINIVLSGYFQAIGKAKRAALLSLLRQGLFLIPLLLIL 397
|
410 420
....*....|....*....|....*
gi 1309054203 408 GVYleMGAVGVWIGLLLGLVFAALL 432
Cdd:cd13143 398 PRL--FGLDGIWLAFPLAEILTLLL 420
|
|
| MATE_MJ0709_like |
cd13147 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, ... |
14-435 |
9.44e-36 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, similar to Methanocaldococcus jannaschii MJ0709; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240552 [Multi-domain] Cd Length: 441 Bit Score: 136.90 E-value: 9.44e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 14 LRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRLLENS 93
Cdd:cd13147 12 IKLSIPMIIAMLLQTLYNLVDAIWVAGLGADALAAIGFVFPLFMIIIGLGNGLGAGASSAISRRIGAKDKEGADNAAVHS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 94 LSLNTIASVILALLMFA-MSFFMDSMGQTpEVVHQAkLYYNTMLFSLFPFLMFFG-----LRqfseGIGITKYAMYITLI 167
Cdd:cd13147 92 ILLGLIISIILTIVLLPfLEPILVLMGAG-EVLDLA-VDYGRIIFLGSIFLIFNNvaygiLR----GEGDTKRAMYAMVA 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 168 ANALNIFLNWILIYGhLGfeaMGVQGAALATLISRILMFLSFLYLIFRHSayNKYLVYFSKKF-FDPKIVREVLKTSIPL 246
Cdd:cd13147 166 GSILNIILDPIFIYT-LG---LGIAGAAWATVISMLISSLVLLYWFFVKK--DTYVSLSLKNFkFDKKIVKDILKVGIPA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 247 SFQNLV-EITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVA 325
Cdd:cd13147 240 SLEQLImSVLMIILNLILVIVAGTDGVAVYTAGWRIVSFAIIPLIGIATAVTSVTGAAYGARNYEKLKTAYNYSIKLGLI 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 326 LMSVSGLAYILFRNYIPMIYT---EDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISYYLVCLP 402
Cdd:cd13147 320 IELIIAILIFIFAPQIAYLFTyseESAHLAPEIVAFLRIMCLFLPFVPFGMMSSSMFQGIGKGLTSLIITILRELIFQVL 399
|
410 420 430
....*....|....*....|....*....|....
gi 1309054203 403 LGYFCGVYLEMGAVGVWIGLLLGLVFAALL-FLW 435
Cdd:cd13147 400 FAYLFAIVLGLGLFGVWWGIVLGNAIGSIVgYLW 433
|
|
| MATE_like_2 |
cd13149 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
14-439 |
3.61e-35 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240554 [Multi-domain] Cd Length: 434 Bit Score: 135.51 E-value: 3.61e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 14 LRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRLLENS 93
Cdd:cd13149 12 IKLTLPMIFGILAMLIFNLTDTFFVGKLGTKELAAISFTFPVVLFLNSLTIGLGIGASAVISRAIGAGDRNKAKRLATDS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 94 LSLNTIASVILALL-MFAMSFFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIANALN 172
Cdd:cd13149 92 LILSLLLSVIVSLLgLFTIPPLFSLLGASGEILPLIVEYMAIWYLGLVFLVLPMVGNAIIRATGDTKRPSLVMLGAALVN 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 173 IFLNWILIYGHLGFEAMGVQGAALATLISRILMFLSFLYLIfrhsAYNKYLVYFSKKFFDPKIV--REVLKTSIPLSFQN 250
Cdd:cd13149 172 VILDPILIFGFGPIPGMGIAGAAIATVISRALGLGAALYFL----HYHHRLIDFSEPSLKALFRswKDILSIGIPAALSN 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 251 LVEITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVALMSVS 330
Cdd:cd13149 248 ILTPLSAAFITALVATYGPAAVAAFGVATRIESFAFIIVMALSSALGPFVGQNWGAGQYERVQEGLKISLKFSLIYGAIL 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 331 GLAYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISYYLVCLPLGYFcGVY 410
Cdd:cd13149 328 GIVLALFAGWLASLFSAEPEVIELITLYLLIVPIGYGGLGILIITSASFNALGKPLYSLGLNLIRVFLLYIPLAYV-GSH 406
|
410 420
....*....|....*....|....*....
gi 1309054203 411 LeMGAVGVWIGLLLGLVFAALLFLWRFDK 439
Cdd:cd13149 407 L-LGFAGVFIGALAGNLIAGILAYFIAKK 434
|
|
| MATE_like_9 |
cd13135 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
11-439 |
4.97e-35 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240540 [Multi-domain] Cd Length: 429 Bit Score: 134.73 E-value: 4.97e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 11 KRNLRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRLL 90
Cdd:cd13135 1 KKINHIAIPLILQNLVSQLQMLVDRAFLGRISIRYYSAVGNVTTPFNTITGFLGSISIGFTILGSQSVGAKDIKRINDYA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 91 ENSLSLNTIASVILALL-MFAMSFFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIAN 169
Cdd:cd13135 81 ISSIVYNSIIGVILFLLwLFGARIIFVLFGVDGQILGYSINYVRIFSIYLLLLGILFTFSSILQGIGETKPIMYGGIIKN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 170 ALNIFLNWILIYGHLGFEAMGVQGAALATLISRILMFLSFLYLIFRHSAYNKYLVYFSKKFFDPKIVREVLKTSIPLSFQ 249
Cdd:cd13135 161 LLNVILDYVLIFGNFGFPRLGIIGAAIATTIANVLNLIILVYLCRKIKKLTFKLSNTKVLKANIRPYKFTIKLGLPLGGE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 250 NLVEiTAFSLSAI-MVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVALMS 328
Cdd:cd13135 241 EFLW-NIGNLAVIrILNRIGELALGIYTLVFGIENIVLMPMYGYSSAALTLVGESIGKKDLKEALRIGNICLGLGLLIYI 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 329 VSGLAYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISYYLVCLpLGYFCG 408
Cdd:cd13135 320 AAAIVFLAFPYKILSLFTNDPELINYSIPYLIFIIIILFFKSINIVYGFAIRAIGDTKWMLYTQIIGTIIVVS-VALLLI 398
|
410 420 430
....*....|....*....|....*....|.
gi 1309054203 409 VYLEMGAVGVWIGLLLGLVFAALLFLWRFDK 439
Cdd:cd13135 399 FVFKLGLAGVYITLFIDEIIRAIINFLKYRK 429
|
|
| MATE_like_5 |
cd13145 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
15-435 |
1.53e-32 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240550 [Multi-domain] Cd Length: 440 Bit Score: 128.10 E-value: 1.53e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 15 RVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRLLENSL 94
Cdd:cd13145 13 KLAIPASVGFFFNTMFNVVDTFFAGKISTEALAALSLSFPIFFIIIAIGVGIGTGTTALIGNALGAGDRRKARRYAAQGL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 95 SLNTIASVILALL-MFAMSFFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIANALNI 173
Cdd:cd13145 93 SFGIILAILLTVIgLFAAPPLFRLLGAEGDYLDLALEYMDVIFAGSIFFLLNFGLNGILNAQGDTKSYRNFLIIGFFLNI 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 174 FLNWILIYGHLGFEAMGVQGAALATLISrilMFLSFLYLIFRHSAYnKYLVYFSKKFFDPK--IVREVLKTSIPLSFQNL 251
Cdd:cd13145 173 ILDPLFIFGGGGIPAMGVSGIALATIIS---QFIGMFYLLYKVRKS-GIISGCRLRDFIPRldVYKEILKQGFPASLNMM 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 252 VEITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVALMSVSG 331
Cdd:cd13145 249 TIGLGIFVITYFVGQFGDEAVAAYGIALRIEQILLLPTIGLNTAVLSIAGQNFGAKKYDRVRETYKKALKYGFVIMVVAT 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 332 LAYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISYYLVCLPLGYFCGVYL 411
Cdd:cd13145 329 VFLLFFAEPLMSLFTNDPAVIAIGAGYLRIDALIFYAYVVLFISVSVLQGLKRPIFALWIGLYRQLVGPALVFWLLVNVL 408
|
410 420
....*....|....*....|....
gi 1309054203 412 EMGAVGVWIGLLLGLVFAALLFLW 435
Cdd:cd13145 409 GLGVTGIWWGIFTIVWSAAIIALL 432
|
|
| MATE_like_6 |
cd13146 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
8-437 |
6.31e-27 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240551 [Multi-domain] Cd Length: 433 Bit Score: 112.11 E-value: 6.31e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 8 PYYKRNLRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVF---GIGFTQGLTPHVGQSFGKGDQA 84
Cdd:cd13146 5 PISPLLIRLALPILIGQLFQLLYNITDTIWISMIDPSDPALVGGIGLVFPLGMIFlalGNGIQVGVSSLLARAIGAQRAK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 85 KVGRLLENSLSLNTIASVILALLMFAMSF-FMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMY 163
Cdd:cd13146 85 ELDQAADSGLALALLAATVIVVLGYIFAEpLLQLLGAKGLLLEYALEYFYYSLPGVPFIMLIGVLMGVLQGEGRTKYMMM 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 164 ITLIANALNIFLNWILIYGHlgfeAMGVQGAALATLISRILMFLSFLY-LIFRHSAYNkylVYFSKKFFDPKIVREVLKT 242
Cdd:cd13146 165 AMLIGTVVNIVLDPILIFVF----DMGVKGAALATVLAQAISLLYLLYvFLIGKSNVT---IHIKLSNISSSVIVEILRV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 243 SIPLSFQNLVEITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHL 322
Cdd:cd13146 238 GLPQMLLQLISSISFLIYNRIIIDIDPVAMTAFTLVGRLDQFILIPIFAISSALLTIAGQNWGRGNYDRMLQILMTAVIL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 323 SVALMSVSGLAYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISYYLVCLP 402
Cdd:cd13146 318 GIVVVLVLVLGYVLVAPWLFSLFTTVPEVVAYAVLQVRTMALALPFVAISILVTEFFQAIGKAWPSLLLTLIRHVFLSVP 397
|
410 420 430
....*....|....*....|....*....|....*.
gi 1309054203 403 LGYFCGVYLEMGAVGVWIGLLLGLVFAALL-FLWRF 437
Cdd:cd13146 398 VVYLLAYVFGKGITGVYFGIVSANFFTALLaMFWGL 433
|
|
| MATE_like_13 |
cd13141 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
10-364 |
5.11e-23 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240546 [Multi-domain] Cd Length: 443 Bit Score: 100.85 E-value: 5.11e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 10 YKRNLRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRL 89
Cdd:cd13141 10 PKHIISMALPIAIGMIIQTLYFLVDLYFVGQLGDAALAGVSLAGNVMFFVMALTQVLNVGTAALVSHAVGRKDQGEANAV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 90 LENSLSLNTIASVILALLMFAMS-FFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIA 168
Cdd:cd13141 90 FNQSLLLAAVLGLVVLVLGYLFGrLYLETLAADAATVEAATTYLYWFIPSLALQFILTVLGAALRGTGIVKPFMVIQILA 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 169 NALNIFLNWILIYGHLGFEAMGVQGAALATLISRILMFLSFLYLIFRHSAYnkylVYFSKKFFDP--KIVREVLKTSIPL 246
Cdd:cd13141 170 VLLNIILAPILITGWGTGRALGVAGAGLASSISVAIAVVLLLYYFLRLEKY----LRLDLALWRPdlPTWKRLLKIGLPS 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 247 SFQNLveITAFSLSAIMVGWS--GKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSV 324
Cdd:cd13141 246 GGEFL--LTFVYMAVIYWALRpfGAAAQAGFGIGSRIMQSLFLPAMAIAFAAPAIAGQNFGAGNYDRVRETFRITAILTT 323
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 1309054203 325 ALMSVSGLAYILFRNYIPMIYTEDVLVRELAAKLLVIAAL 364
Cdd:cd13141 324 ALMLVLTLLCQLVPELLVTPFSDDAAVIAVAATFLRYVSW 363
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
19-178 |
6.73e-23 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 94.55 E-value: 6.73e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 19 PVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRLLENSLSLNT 98
Cdd:pfam01554 1 PIALENLLQSLYSLIDTLFVGHLGAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 99 IASVILALLMFAMS-FFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIANALNIFLNW 177
Cdd:pfam01554 81 LLSLPIALLVLLFSePILSLFGQDEEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIISLLLNIPLNY 160
|
.
gi 1309054203 178 I 178
Cdd:pfam01554 161 L 161
|
|
| PRK10189 |
PRK10189 |
EmmdR/YeeO family multidrug/toxin efflux MATE transporter; |
1-438 |
2.17e-22 |
|
EmmdR/YeeO family multidrug/toxin efflux MATE transporter;
Pssm-ID: 182293 [Multi-domain] Cd Length: 478 Bit Score: 99.42 E-value: 2.17e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 1 MFLREYFPyykrnlrVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGK 80
Cdd:PRK10189 26 LFWREITP-------LAVPIFIENLCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGK 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 81 GDQAKVGRLLENSLSLNTIASVILALLM-FAMSFFMDSMG--QTPEVVHQAKLYYNTMLFSlFPFLMFF-----GLRqfs 152
Cdd:PRK10189 99 RDRRRARAAARQSLVIMTLFAVLLAVLIhFFGEQIIDLVAgdATPEVKALALTYLELTVWS-YPAAAITligsgALR--- 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 153 eGIGITKYAMYITLIANALNIFLNWILIYGHLGFEAMGVQGAALATLISRILMFLSFLYLIFRhsAYNKYLVYFSKKFFD 232
Cdd:PRK10189 175 -GAGNTKIPLLINGGMNILNIIISSILIYGLFSWQGLGFVGAGLGLTISRYIGAVAIIWVLMI--GFNPALRISLKSYFK 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 233 P---KIVREVLKTSIPLSFQNLVEITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDY 309
Cdd:PRK10189 252 PlnfAIIWEVMGIGIPASIESVLFNGGKLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGTRLGKGQI 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 310 KAMRTAGFAAIHLSVALMSVSGLAYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPL 389
Cdd:PRK10189 332 AQAERQLRHVFWLSTLGLTAIAWLSAPFAGLLASFYTQDPDVKHVVKILIWLNALFMPIWAASWVLPAGLKGARDARYAM 411
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 1309054203 390 ILSIISYYLVCLPLGYFCGVYLEMGAVGVWIGLLLGLVFAALLFLWRFD 438
Cdd:PRK10189 412 WVSMLGMWGCRVVAGYILGIMLGFGVVGVWMGMFLDWAVRGVLFYWRMV 460
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
245-406 |
3.27e-21 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 89.93 E-value: 3.27e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 245 PLSFQNLVEITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSV 324
Cdd:pfam01554 1 PIALENLLQSLYSLIDTLFVGHLGAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 325 ALMSVSGLAYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISyYLVCLPLG 404
Cdd:pfam01554 81 LLSLPIALLVLLFSEPILSLFGQDEEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIIS-LLLNIPLN 159
|
..
gi 1309054203 405 YF 406
Cdd:pfam01554 160 YL 161
|
|
| MATE_like_3 |
cd13148 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
14-435 |
8.75e-21 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240553 [Multi-domain] Cd Length: 441 Bit Score: 94.26 E-value: 8.75e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 14 LRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFIL-GMVFGIGFTQGLTPHVGQSFGKGDQAKVGRLLEN 92
Cdd:cd13148 15 LRLALPNILALLVQTLVGLAETYFVGQLGTDALAGVALVFPLLMLtQMMSNGAMGGGVSSAIARALGAGDRERAEALVWH 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 93 SLSLNTIASVI--LALLMFAMSFFMdSMGQTPEVVHQAkLYYNTMLFSLFPFLMFFG-LRQFSEGIGITKYAMYITLIAN 169
Cdd:cd13148 95 ALVIALAGGLVfsLLFLLFGPALYR-LLGGRGEALDAA-LAYSNVLFSGAILIWLVNlLAAALRGTGNMRVPALVTLVGA 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 170 ALNIFLNWILIYGHLGFEAMGVQGAALATLISRILMFLSFL-YLIFRHSAYNKYLVYFSkkfFDPKIVREVLKTSIPLSF 248
Cdd:cd13148 173 VVQIPLSPGLILGWGPLPRLGVAGAAVAAVLYYALAALVLLrYLASGRSRLRLRLRALR---LERRLFRDILRVGLLAAL 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 249 QNLVEITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVALMS 328
Cdd:cd13148 250 SPLQTNLTVLLLTGLVGRFGTAALAGYGIGSRLEFLLIPLVFGLGAAMTAMVGMNIGAGQIARARRIAWTGALMAAVLAG 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 329 VSGLAYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISyYLVCLPLGYFCG 408
Cdd:cd13148 330 AIGLVLALFPELWLGLFTHDPAVLAAGASYLRIVGPFYGFFGLGLALYFASQGAGRMLWPVLAGTLR-LLIAAGGGWIAV 408
|
410 420
....*....|....*....|....*..
gi 1309054203 409 VYLEMGAVGVWIGLLLGLVFAALLFLW 435
Cdd:cd13148 409 ALFGAGLAGLFAAAAAAMVAYGLVTAA 435
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
3-212 |
3.55e-17 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 83.27 E-value: 3.55e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 3 LREYFPYYKRNLRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGD 82
Cdd:COG0534 221 LRPDRKILKRILRIGLPAGLQQLAESLGFLVLNALVARLGTAAVAAYGIALRIESLAFMPALGLGQAAQPLVGQNLGAGD 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 83 QAKVGRLLENSLSLNTIASVILALLMFAMS-FFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYA 161
Cdd:COG0534 301 YDRARRAARLALLLALGIGLLLALLLFLFPePIIGLFTDDPEVIALAATYLRIAALFQPFDGLQFVLSGALRGAGDTRFP 380
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1309054203 162 MYITLIANALnIFLNWILIyghLGFEAMGVQGAALATLISRILMFLSFLYL 212
Cdd:COG0534 381 MIISLLRLWL-VRLPLAYL---LAFLGLGLTGVWLALPIGEVLRALLLLLR 427
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
230-437 |
3.33e-16 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 80.19 E-value: 3.33e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 230 FFDPKIVREVLKTSIPLSFQNLVEITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDY 309
Cdd:COG0534 1 LTEGPILKLLLRLALPIILGNLLQSLYGLVDTIFVGRLGTAALAAVGLAFPIFFLLIALGIGLGVGGTALVAQALGAGDR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 310 KAMRTAGFAAIHLSVALMSVSGLAYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPL 389
Cdd:COG0534 81 EEARRVLGQALLLALLLGLLLTLLGLLFAPPLLRLLGADPEVLALARDYLRIILLGLPFLLLFNVLNGILRGLGDTKTPM 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1309054203 390 ILSIISYyLVCLPLGYFCGVYLEMGAVGVWIGLLLGLVFAALLFLWRF 437
Cdd:COG0534 161 IIMLIGN-VLNIVLDPLLIFGGGLGVAGAALATVISQAVSALLLLYYL 207
|
|
| MATE_yoeA_like |
cd13138 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
11-216 |
4.51e-10 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240543 [Multi-domain] Cd Length: 431 Bit Score: 61.32 E-value: 4.51e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 11 KRNLRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRLL 90
Cdd:cd13138 225 KEILKIGLPSALQQSLVSISFLIINSIVNSYGVVASAAYGIANKINSFAFLPPSAIGQAVSTFVAQNIGAGKIERAKKGL 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 91 ENSLSLNTIASVILALLMFAMSFFMDSM-GQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIAN 169
Cdd:cd13138 305 RTGIIISLIIGLIIILLVFFFAPQLLGLfTSDPEVIEIGAEYLRIYSIDYILFGILFVFNGLFRGLGKTKFPMIISILRL 384
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1309054203 170 -ALNIFLNWILIYghlgFEAMGVQGAALATLISRILMFLSFLYLIFRH 216
Cdd:cd13138 385 wLVRIPLAYLLSR----LTGLGLFGIWLAMPISNILSAIICIIYYRKG 428
|
|
| MATE_like_8 |
cd13134 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
237-442 |
5.13e-09 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240539 [Multi-domain] Cd Length: 438 Bit Score: 57.90 E-value: 5.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 237 REVLKTSIPLSFQNLVEITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAG 316
Cdd:cd13134 3 LSLFALAWPIFIELLLQMLLGTIDTFMLSRYSDNAVAAVGVANQILFLLILIFSFISTGTSILIAQYLGAKDKKKARQIA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 317 FAAIHLSVALMSVSGLAYILFRNYIPMIYTEDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIIS- 395
Cdd:cd13134 83 GVALLFNLLLGLVFSLLLLFFGAELLRLMGLPPELLALGSTYLRIVGGSLFLQALSLTLSAILRSHGRTKIPMYVSLIMn 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1309054203 396 -------YYLVCLPLGYfcgvyLEMGAVGVWIGLLLGLVFAALLFLWRFDKISN 442
Cdd:cd13134 163 ilnivgnYLLIFGWFGL-----PKLGVAGVAISTVISRAVGLVLLFILLFRKLK 211
|
|
| RfbX |
COG2244 |
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane ... |
14-210 |
3.56e-08 |
|
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441845 [Multi-domain] Cd Length: 366 Bit Score: 54.95 E-value: 3.56e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 14 LRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGV-SFANSIFILGMVFGIGFTQGLTPHVGQSFGKGDQAKVGRLLEN 92
Cdd:COG2244 176 LKYSLPLLLSGLLGLLLTNLDRLLLGALLGPAAVGIySAAYRLASLLLLLITALSQVLFPRLSRLLAEGDREELRRLYRK 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 93 SLSLNTIASVILALLMFAMS-FFMDSMgqTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIANAL 171
Cdd:COG2244 256 ALRLLLLLGLPLALGLALLApPLLSLL--FGPEYAEAAPVLPILALGALFLALSGVLSNLLLALGRTRLLLIISLIGAVL 333
|
170 180 190
....*....|....*....|....*....|....*....
gi 1309054203 172 NIFLNWILIYghlgfeAMGVQGAALATLISRILMFLSFL 210
Cdd:COG2244 334 NLVLNLLLIP------RYGLVGAAIATLLSYLVLLLLLL 366
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
2-214 |
7.07e-08 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 54.25 E-value: 7.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 2 FLREYFPYYKRNLRVAIPVMLTQ-AGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGK 80
Cdd:cd12082 210 LLKPDLELLRRLLRIGLPSAIQNsLLSLGLLIIVAIVAAFGGAAALAAYTVAFRIASLAFMPALGLAQAALPVVGQNLGA 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 81 GDQAKVGRLLENSLSLNTIASVILALLMFAMS-FFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITK 159
Cdd:cd12082 290 GNFDRARRITWVALLIGLLIGAVLGLLILLFPePILSLFTNDPEFLELAVSYLRILAIYYLFVGIGYVLQAGFQAAGRTL 369
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1309054203 160 YAMYITLIANALNIFLNWILiyghLGFEAMGVQGAALATLISRILMFLSFLYLIF 214
Cdd:cd12082 370 KSLIVSLLSYWVVRLPLAYV----LAYLGLGLYGIWLALVISLILAALVLLLFFR 420
|
|
| SpoVB |
COG5841 |
Stage V sporulation protein SpoVB/SpoIIIF, required for spore cortex synthesis [Cell cycle ... |
4-231 |
1.94e-07 |
|
Stage V sporulation protein SpoVB/SpoIIIF, required for spore cortex synthesis [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444543 [Multi-domain] Cd Length: 532 Bit Score: 53.24 E-value: 1.94e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 4 REYFPYYKRNLRVAIPVMLTQAGQITVNLADNIMVGHLgtAELAGVS-------------FANSIFILGMVFGIGFTQGL 70
Cdd:COG5841 226 ESSKDILKELLRIAIPITLSSLVLPLFQLIDSFTVPRR--LQAAGLSaseatslygilsgMAQPLVNLPTVLATALATSL 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 71 TPHVGQSFGKGDQAKVGRLLENSLSLNTIASVILALLMFAMS-FFMDSMGQTPEVVHqaklyyntMLFSLFPFLMFFGLR 149
Cdd:COG5841 304 VPAISEAFAKKDRKLVRRRINQALRLTLLIGLPAAVGLAVLAePINTLLFGNPEGGG--------ILAILAPSAIFLSLQ 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 150 QFS----EGIGITKYAMYITLIANALNIFLNWILIYghlgfeAMGVQGAALATLISRILMFLSFLYLIFRHSAYNKYLVY 225
Cdd:COG5841 376 QVTtgilQGLGKQKIPVINLLIGLLVKIILNYLLVP------LFGIYGAALATVIGYLVAAILNLAALKKYTGFKLDLRR 449
|
....*.
gi 1309054203 226 FSKKFF 231
Cdd:COG5841 450 RLLKPL 455
|
|
| MATE_Wzx_like |
cd13128 |
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
36-265 |
1.18e-06 |
|
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240533 [Multi-domain] Cd Length: 402 Bit Score: 50.62 E-value: 1.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 36 IMVGHLGTAELAGVSFANSIFILGMVFGIGftqGLTPHVGQSFGKGDQAKVGRLLENSLSLNTIASVILALLMFAMSFFM 115
Cdd:cd13128 25 YLARYLGPEGFGILSLALAFVGLFSIFADL---GLPTALVREIARYRKEKIREIISTSLVLKLILGILALLLLFLFAFLI 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 116 DsmGQTPEVVhqakLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIANALNIFLNWILIYGHLGFEamgvqGAA 195
Cdd:cd13128 102 A--FYDPELV----LLLYILALSLPFSALNSLFRGIFQGFEKMKYIVIARIIESVLSLILALILVLLGGGLI-----GFA 170
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 196 LATLISRILMFLSFLYLifrhsaYNKYLVYFSKKFFDPKIVREVLKTSIPLSFQNLVEITAFSLSAIMVG 265
Cdd:cd13128 171 LAYLIASVLSAILLLYI------YRKKILLPKFFSFDLKLAKELLRFSIPLALSGIFSLIYTRIDTIMLG 234
|
|
| PRK10367 |
PRK10367 |
DNA-damage-inducible SOS response protein; Provisional |
15-360 |
1.49e-06 |
|
DNA-damage-inducible SOS response protein; Provisional
Pssm-ID: 182413 [Multi-domain] Cd Length: 441 Bit Score: 50.12 E-value: 1.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 15 RVAIPVMLTQAGQITVNLADNIMVGHLGTAE-LAGV---SFANSIFILGMVFGIGFTQGLTphvGQSFGKGDQAKVGRLL 90
Cdd:PRK10367 13 RLALPMIFSNITVPLLGLVDTAVIGHLDSPVyLGGVavgATATSFLFMLLLFLRMSTTGLT---AQAFGAKNPQALARAL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 91 ENSLSLNTIASVILALLMFAMSFFMDSM-GQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIAN 169
Cdd:PRK10367 90 VQPLLLALGAGALIALLRTPLIDLALHIvGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVGN 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 170 ALNIFLNWILIYGhLGfeaMGVQGAALATLISRILMFLSFLYLIFRHSAYNKYLVYFSKKFFDPKIvREVLKTSIPLSFQ 249
Cdd:PRK10367 170 ILNIVLDLWLVMG-LH---MNVQGAALATVIAEYATLLIGLLMVRKVLKLRGISLEMLKTAWRGNF-RRLLALNRDIMLR 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 250 NLVEITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVALMSV 329
Cdd:PRK10367 245 SLLLQLCFGAITVLGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACRQSGIVALL 324
|
330 340 350
....*....|....*....|....*....|.
gi 1309054203 330 SGLAYILFRNYIPMIYTEDVLVRELAAKLLV 360
Cdd:PRK10367 325 FSLVYALAGEHIIALLTSLPQIQQLADRYLI 355
|
|
| MATE_Wzx_like |
cd13128 |
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
11-213 |
1.66e-06 |
|
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240533 [Multi-domain] Cd Length: 402 Bit Score: 49.85 E-value: 1.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 11 KRNLRVAIPVMLTQAGQITVNLADNIMVGH-LGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGKgDQAKVGRL 89
Cdd:cd13128 206 KELLRFSIPLALSGIFSLIYTRIDTIMLGYfLGDAAVGIYNAAYRIAELLLFIPSAISTALFPRISELYKN-DKDELKKL 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 90 LENSLSLNTIASVILALLMFAMSFFMDSMGQTPEVVhQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIAN 169
Cdd:cd13128 285 LKKSFKYLFLISLPIAIGLFLFAEPIITLLFGEEYL-PAALVLQILAWGFLFIFLNGIFGSILQAIGKQKLTLKILLIGA 363
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1309054203 170 ALNIFLNWILIYghlgfeAMGVQGAALATLISRILMFLSFLYLI 213
Cdd:cd13128 364 LLNVILNLLLIP------KYGIIGAAIATLISEFIIFILLLYLL 401
|
|
| MurJ |
COG0728 |
Lipid II flippase MurJ/MviN (peptidoglycan biosynthesis) [Cell wall/membrane/envelope ... |
8-290 |
1.90e-06 |
|
Lipid II flippase MurJ/MviN (peptidoglycan biosynthesis) [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440492 [Multi-domain] Cd Length: 503 Bit Score: 50.15 E-value: 1.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 8 PYYKRNLRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGM-VFGIGFTQGLTPHVGQSFGKGDQAKV 86
Cdd:COG0728 219 PGVRRVLKLMLPALLGVSVSQINLLVDTILASFLPEGSVSALYYADRLYQLPLgLFGVAIGTALLPRLSRAAAAGDLEEF 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 87 GRLLENSLSLNTIASVILALLMFAMSFFMDSM----GQ-TPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYA 161
Cdd:COG0728 299 RRTLSRGLRLVLLLTLPAAVGLIVLAEPIVRLlferGAfTAEDTALTALALAAYALGLPAFALVKVLARAFYARQDTRTP 378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 162 MYITLIANALNIFLNWILIYghlgfeAMGVQGAALATLISRILMFLSFLYLIFRHSAYnkylvyfskkFFDPKIVREVLK 241
Cdd:COG0728 379 VRIAVIAVVVNIVLNLLLVP------PLGHAGLALATSLSALVNALLLLVLLRRRLGG----------LPLRGILRTLLK 442
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 1309054203 242 TSIPLSFQNLVEITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLAL 290
Cdd:COG0728 443 LLLASLVMGAVLWLLLRLLGDWLGGGLLGRLLALALLILVGAAVYFALL 491
|
|
| MATE_SpoVB_like |
cd13124 |
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related ... |
6-216 |
3.14e-06 |
|
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240529 [Multi-domain] Cd Length: 434 Bit Score: 49.39 E-value: 3.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 6 YFPYYKRNLRVAIPVMLTQAGQITVNLADNIMVGHL-----GTAELAGVSF------ANSIFILGMVFGIGFTQGLTPHV 74
Cdd:cd13124 219 TKEILKELLSYAIPITLSSLILPLLQLIDSFTVPRRlqaagLSESEATALYgiltgrAQPLVQLPTVIATALSTSLVPAI 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 75 GQSFGKGDQAKVGRLLENSLSLNTIASVILALLMFAMSFFMDSMgqtpevvhqakLYYNT----MLFSLFPFLMFFGLRQ 150
Cdd:cd13124 299 SEAYAKGDKKELRRRINQALRLTLLIGLPAAVGLAVLAEPINTL-----------LFGDSegglILQILAPSILFLSLQQ 367
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 151 FS----EGIGITKYAMYITLIANALNIFLNWILIYGhlgfeaMGVQGAALATLISRILMFLSFLYLIFRH 216
Cdd:cd13124 368 VTaailQGLGKVKIPVINLLIGLLVKIVLNYVLIPI------FGIYGAAIATVIGFLVAALLNLRALKKL 431
|
|
| MATE_MurJ_like |
cd13123 |
MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
8-216 |
1.29e-05 |
|
MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli MurJ (MviN) has been identified as essential for murein biosynthesis. It has been suggested that MurJ functions as the peptidoglycan lipid II flippase which is involved in translocation of lipid-anchored peptidoglycan precursors across the cytoplasmic membrane, though results obtained in Bacillus subtilis seem to indicate that its MurJ homologs are not essential for growth. Some MviN family members (e.g. in Mycobacterium tuberculosis) possess an extended C-terminal region that contains an intracellular pseudo-kinase domain and an extracellular domain resembling carbohydrate-binding proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240528 [Multi-domain] Cd Length: 420 Bit Score: 47.45 E-value: 1.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 8 PYYKRNLRVAIPVMLTQA-GQITVnLADNIMVGHLGTAELAGVSFANSIFILGM-VFGIGFTQGLTPHVGQSFGKGDQAK 85
Cdd:cd13123 212 PGVRRVLKLMLPALLGVSvSQINL-LVDTILASFLPEGSISALYYADRLYQLPLgIFGVAIATALLPRLSRLAAAGDLDE 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 86 VGRLLENSLSLNTIASVILALLMFAMSFFMDSM----GQ-TPEVVHQAKLYYNTMLFSLFPFLM-------FFGLRQfse 153
Cdd:cd13123 291 FRRTLSRGLRLVLFLLLPAAVGLIVLAEPIVRLlferGAfTAEDTLMTASALAAYALGLPAFALvkllsraFYALKD--- 367
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1309054203 154 gigiTKYAMYITLIANALNIFLNWILIyghlgfEAMGVQGAALATLISRILMFLSFLYLIFRH 216
Cdd:cd13123 368 ----TKTPVKIAVIAVAVNILLNLLLI------KPLGHVGLALATSLSAWVNALLLLVLLRRR 420
|
|
| MATE_SpoVB_like |
cd13124 |
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related ... |
80-439 |
7.90e-05 |
|
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240529 [Multi-domain] Cd Length: 434 Bit Score: 44.77 E-value: 7.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 80 KGDQAKVGRLLENSLSLNTIASVILALLMFAMSFFMDSMgqtpeVVHQAKLYYNTMLFSLFPFLMFF--GLRQFSEGIGI 157
Cdd:cd13124 65 LGDYKGARRIFRVSLILLLILGLVFFLLLFFGAPFLAQL-----LLGDPRLAPVIRALAPAILIVPLlsVLRGYFQGLQN 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 158 tkyaMYITLIAN--------ALNIFLNWILIYGHLGFEaMGVQGAALATLISrilMFLSFLYLIFRHSAYNKYLVYFSKK 229
Cdd:cd13124 140 ----MTPTAVSQvieqivrvIVILVLAYLLLPVGGGLY-YAAAGATFGAVIG---ALAGLLVLLYYYRKKRRELKRLLRK 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 230 FFDPK-----IVREVLKTSIPLSFQNLVEITAFSLSAIMVGWSGKVALASHQVAMSM-SSFSFM----------LALGVG 293
Cdd:cd13124 212 SPRSKistkeILKELLSYAIPITLSSLILPLLQLIDSFTVPRRLQAAGLSESEATALyGILTGRaqplvqlptvIATALS 291
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 294 AASTIRVSHQYGFGDYKAMRTAGFAAIHLSVALMSVSGLAYILFRNYI-PMIYTEDvlvreLAAKLLVIAALFQIFDAIQ 372
Cdd:cd13124 292 TSLVPAISEAYAKGDKKELRRRINQALRLTLLIGLPAAVGLAVLAEPInTLLFGDS-----EGGLILQILAPSILFLSLQ 366
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1309054203 373 LSGLAALRALADVKIPLILSIISyYLVCLPLGYFCGVYLemGAVGVWIGLLLGLVFAALLFLWRFDK 439
Cdd:cd13124 367 QVTAAILQGLGKVKIPVINLLIG-LLVKIVLNYVLIPIF--GIYGAAIATVIGFLVAALLNLRALKK 430
|
|
| MATE_like_9 |
cd13135 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
1-181 |
1.26e-04 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240540 [Multi-domain] Cd Length: 429 Bit Score: 44.21 E-value: 1.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 1 MFLREYFPYYKRNLRVAIPVMLTQAGQITVNLADNIMVGHLGTAELAGVSFANSIFILGMVFGIGFTQGLTPHVGQSFGK 80
Cdd:cd13135 218 KVLKANIRPYKFTIKLGLPLGGEEFLWNIGNLAVIRILNRIGELALGIYTLVFGIENIVLMPMYGYSSAALTLVGESIGK 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 81 GDQAKVGRLLENSLSLNTIASVILALLMFAMSFFMDSMGQT-PEVVHQAKLYYNTMLFSLFP----FLMFFGLRqfseGI 155
Cdd:cd13135 298 KDLKEALRIGNICLGLGLLIYIAAAIVFLAFPYKILSLFTNdPELINYSIPYLIFIIIILFFksinIVYGFAIR----AI 373
|
170 180
....*....|....*....|....*.
gi 1309054203 156 GITKYAMYITLIANALNIFLNWILIY 181
Cdd:cd13135 374 GDTKWMLYTQIIGTIIVVSVALLLIF 399
|
|
| MATE_like_1 |
cd13140 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
234-440 |
2.54e-04 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240545 [Multi-domain] Cd Length: 435 Bit Score: 43.28 E-value: 2.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 234 KIVREVLKTSIPLSFQNLVEItAFSLSAIM-VGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAM 312
Cdd:cd13140 2 PILKTLLRLALPIMGTSFIQM-AYNLTDMFwVGRLGSDAVAAVGTAGFFVWLAYALALLSKIGAQVKVSQSIGAKDEKEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 313 RTAGFAAIHLSVALMSVSGLAYILFRNYIPMIYT-EDVLVRELAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLIL 391
Cdd:cd13140 81 RKYARNALQLNLLLGILYGLLLLLFAKPLIGFFNlGDAEVISLAITYLRIVALGLIFSFLNPVFTGIFNALGDSKTPFII 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1309054203 392 SIISYYL--VCLPLGYF-CGVYLEMGAVGVWIGLLLGLVFAALLFLWRFDKI 440
Cdd:cd13140 161 NAIGLVLniILDPLLIFgFGPFPALGVAGAALATVLAQAIVFLLFLYALKKK 212
|
|
| RfbX |
COG2244 |
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane ... |
36-434 |
4.39e-04 |
|
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441845 [Multi-domain] Cd Length: 366 Bit Score: 42.24 E-value: 4.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 36 IMVGHLGTAELAGVSFANSIFILGMVFgigFTQGLTPHVGQSFGKGDQAKVGRLLENSLSLNTIASVILALLMFAMSFFM 115
Cdd:COG2244 28 LLARLLGPEEYGLFALALSIVALLSVL---ADLGLSTALVRFIAEYREEELRRLLSTALLLRLLLSLLLALLLLLLAPFI 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 116 DSMGQTPEVVhqakLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIANALNIFLNWILIYGHLGFEAMgvqgaa 195
Cdd:COG2244 105 AALLGEPELA----LLLLLLALALLLSALSAVLLALLRGLERFKLLALINILSSLLSLLLALLLALLGLGLWGL------ 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 196 latlisrilmflsflylifrhsaynkylvyfskkffdpkivreVLKTSIPLSFQNLVEITAFSLSAIMVG-WSGKVALAS 274
Cdd:COG2244 175 -------------------------------------------VLKYSLPLLLSGLLGLLLTNLDRLLLGaLLGPAAVGI 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 275 HQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAMRTAGFAAIHLSVALMSVSGLAYILFRNYI-PMIYTEDVLVre 353
Cdd:COG2244 212 YSAAYRLASLLLLLITALSQVLFPRLSRLLAEGDREELRRLYRKALRLLLLLGLPLALGLALLAPPLlSLLFGPEYAE-- 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 354 lAAKLLVIAALFQIFDAIQLSGLAALRALADVKIPLILSIISyyLVCLPLGYFCGVYLeMGAVGVWIGLLLGLVFAALLF 433
Cdd:COG2244 290 -AAPVLPILALGALFLALSGVLSNLLLALGRTRLLLIISLIG--AVLNLVLNLLLIPR-YGLVGAAIATLLSYLVLLLLL 365
|
.
gi 1309054203 434 L 434
Cdd:COG2244 366 L 366
|
|
| vmrA |
PRK09575 |
MATE family efflux transporter; |
34-240 |
9.55e-04 |
|
MATE family efflux transporter;
Pssm-ID: 236576 [Multi-domain] Cd Length: 453 Bit Score: 41.52 E-value: 9.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 34 DNIMVGH-LGTAELAGVSFAnsIFILGMVFGIGFTQGLTPHVGQSF--GKGDQAKVGRLLENSLSLNTIASVILALLMFA 110
Cdd:PRK09575 35 DGIFIGHyVGAEGLAGINMA--WPVIGIILGIGLMVGMGTGSLLSIkrGEGDLEKAKRILTTGLLLLLLLGPIVSVILFL 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 111 MS-FFMDSMGQTPEVVHQAKLYYNTMLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIANALNIFLNWILIyghlGFEAM 189
Cdd:PRK09575 113 FAdDFLRAQGAEGRTLELALQYIQVLIWGCLFTLGAIALPFLLRNDESPNLATGLMVIGALINIVLDYLFI----GWLDW 188
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1309054203 190 GVQGAALATLISRILMFLsfLYLIFRHSAYNKYLVYFSKKFFDPKIVREVL 240
Cdd:PRK09575 189 GLTGAAIATALAQLVVTV--LGLGYFFSSRANIRLTLKELRFNWSLAPKIV 237
|
|
| MATE_like_7 |
cd13133 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
233-435 |
1.34e-03 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240538 [Multi-domain] Cd Length: 438 Bit Score: 40.97 E-value: 1.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 233 PKIVREVLKTSIPLSFQNLVEITAFSLSAIMVGWSGKVALASHQVAMSMSSFSFMLALGVGAASTIRVSHQYGFGDYKAM 312
Cdd:cd13133 1 PGGYREILKIALPLVLSMLSQTVMGFTDRAFLGRLSEVALAASGPAGVLYFAILMLFFGLSSGVQVFVAQYNGAGRYSRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 313 RTAGFAAIHLSVALMSVSGLAYILFRNYI--PMIYTEDVLVRELA-AKLLVIAALFQIFdaiqlsgLAALRA----LADV 385
Cdd:cd13133 81 GRVLWQGLYFSLLLAPLLALLSALAAPLLflLLGHSPEVQALEVEyFRIRILGAPFSLL-------GAALRAffsgIGRT 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1309054203 386 KIPLILSIISyYLVCLPLGYFC----GVYLEMGAVGVWIGLLLGLVFAALLFLW 435
Cdd:cd13133 154 RVVMVANLVM-VVVNIVLDYALifgkLGFPAMGIAGAAIATVIAEAVSLLFFLL 206
|
|
| Polysacc_synt_C |
pfam14667 |
Polysaccharide biosynthesis C-terminal domain; This family represents the C-terminal integral ... |
135-231 |
9.48e-03 |
|
Polysaccharide biosynthesis C-terminal domain; This family represents the C-terminal integral membrane region of polysaccharide biosynthesis proteins.
Pssm-ID: 434111 [Multi-domain] Cd Length: 141 Bit Score: 36.40 E-value: 9.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309054203 135 MLFSLFPFLMFFGLRQFSEGIGITKYAMYITLIANALNIFLNWILIYghlgfeAMGVQGAALATLISRILMFLSFLYLIF 214
Cdd:pfam14667 5 LALSIIFLSLSTVLTSILQGLGRTKLALIALLIGALVKLILNLLLIP------LFGIVGAAIATVISLLVVALLNLYYLR 78
|
90
....*....|....*..
gi 1309054203 215 RHSAYNKYLVYFSKKFF 231
Cdd:pfam14667 79 RYLGLRLLLRRLLKPLL 95
|
|
| |
