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Conserved domains on  [gi|1304690525|gb|PKE84407|]
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protein translocase subunit SecF [Escherichia coli]

Protein Classification

protein translocase subunit SecF( domain architecture ID 11417410)

protein translocase subunit SecF is part of the Sec protein translocase complex; SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA

Gene Ontology:  GO:0015450|GO:0043952|GO:0065002
TCDB:  2.A.6.4

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SecF COG0341
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ...
 9-302 1.04e-138

Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 440110 [Multi-domain]  Cd Length: 291  Bit Score: 394.03  E-value: 1.04e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525   9 QLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVRGFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNF 88
Cdd:COG0341     1 RLFPGNTNIDFMKKRKIWFAISAVLILASIVSLFTRGLNLGIDFTGGTLIEVSFEQPVDLEEVREALEEAGLGDASVQTF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  89 GSSHDIMVRMPPAEGETGGQVlgSQVLKVINESTNqNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWR 168
Cdd:COG0341    81 GSDNDVLIRTPPLDGESAEEV--EKVRAALKEAFG-DVEIVRVEFVGPTVGKELTRKALLALLVALIGILIYIAFRFEWR 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 169 LAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVSLTQTLHRT 248
Cdd:COG0341   158 FAVGAVVALLHDVLITLGIFSLFGLEFDLTFIAALLTIIGYSLNDTVVVFDRIRENLRKYRKMTLAEIINLSINQTLSRT 237

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1304690525 249 LITSGTTLMVILMLYLFGGPVLEGFSLTMLIGVSIGTASSIYVASALALKLGMK 302
Cdd:COG0341   238 INTSLTTLLVVLALLFFGGETLRDFALALLIGIIVGTYSSIFIASPLLLWLGKR 291
 
Name Accession Description Interval E-value
SecF COG0341
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ...
 9-302 1.04e-138

Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440110 [Multi-domain]  Cd Length: 291  Bit Score: 394.03  E-value: 1.04e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525   9 QLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVRGFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNF 88
Cdd:COG0341     1 RLFPGNTNIDFMKKRKIWFAISAVLILASIVSLFTRGLNLGIDFTGGTLIEVSFEQPVDLEEVREALEEAGLGDASVQTF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  89 GSSHDIMVRMPPAEGETGGQVlgSQVLKVINESTNqNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWR 168
Cdd:COG0341    81 GSDNDVLIRTPPLDGESAEEV--EKVRAALKEAFG-DVEIVRVEFVGPTVGKELTRKALLALLVALIGILIYIAFRFEWR 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 169 LAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVSLTQTLHRT 248
Cdd:COG0341   158 FAVGAVVALLHDVLITLGIFSLFGLEFDLTFIAALLTIIGYSLNDTVVVFDRIRENLRKYRKMTLAEIINLSINQTLSRT 237

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1304690525 249 LITSGTTLMVILMLYLFGGPVLEGFSLTMLIGVSIGTASSIYVASALALKLGMK 302
Cdd:COG0341   238 INTSLTTLLVVLALLFFGGETLRDFALALLIGIIVGTYSSIFIASPLLLWLGKR 291
3a0501s07 TIGR00966
protein-export membrane protein SecF; This bacterial protein is always found with the ...
 45-292 9.75e-116

protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273368 [Multi-domain]  Cd Length: 246  Bit Score: 334.24  E-value: 9.75e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  45 GFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNFGSSHDIMVRMPPAEGETGGQVlGSQVLKVINEsTNQ 124
Cdd:TIGR00966   1 GFNFGIDFTGGTVIETRLEQAADVAEVRDVLEKAGIEGVVIQEFGSSHTIMIRIPTLDTEQSEEL-REALEEALKN-VDP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 125 NAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLM 204
Cdd:TIGR00966  79 DAEIRSIDAVGPSVGGELARKAVLALLAALVLILIYITVRFEWRFALGAIVALVHDVIITVGVYSLFGIEVNLTTVAALL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 205 SVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLTMLIGVSIG 284
Cdd:TIGR00966 159 TIIGYSINDTVVVFDRIRENLRKYTRKTFTEVINLSINQTLSRTINTSLTTLLAVLALYVFGGGVIKDFSLALLVGVIVG 238


                  ....*...
gi 1304690525 285 TASSIYVA 292
Cdd:TIGR00966 239 TYSSIFIA 246
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 17-321 1.06e-93

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 294.06  E-value: 1.06e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  17 YDFMRWDYWAFGISGLLLIAAIVIMGVRGFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNFGS-SHDIM 95
Cdd:PRK13024  449 IDFVKKRKWFLIFSIVLVIAGIIIFFIFGLNLGIDFTGGTRYEIRTDQPVDLEQVRADLKELGLGEVNIVTFGSdNNQVL 528

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  96 VRMPPAEgETGGQVLGSQVLKVINESTNQ-NAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWRLAAGVV 174
Cdd:PRK13024  529 VRTYGIL-SDDEEADTEIVAKLKNALKNDkGGTIPSSETVGPTVGKELARNAIIAVLIALIGILLYILIRFEWTFSLGAI 607

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 175 IALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGT 254
Cdd:PRK13024  608 LALLHDVLIVIGFFSLFRLEVDLTFIAAILTIIGYSINDTVVVFDRIRENLRLYKKKDLREIVNKSINQTLSRTINTSLT 687

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1304690525 255 TLMVILMLYLFGGPVLEGFSLTMLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPSI 321
Cdd:PRK13024  688 TLLVLLALLIFGGSSLRNFSLALLVGLIVGTYSSIFIAAPLWLDLEKRRLKKKKKRKKVKKWEVEKI 754
SecD_SecF pfam02355
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ...
 114-302 1.14e-81

Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.


Pssm-ID: 280510 [Multi-domain]  Cd Length: 189  Bit Score: 245.59  E-value: 1.14e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 114 VLKVINESTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWRLAAGVVIALAHDVIITLGILSLFHI 193
Cdd:pfam02355   1 VVEALLKNVGPDAEIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEWRFALGAIIALAHDVIITVGVFSLFGI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 194 EIDLTIVASLMSVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGF 273
Cdd:pfam02355  81 EVDLATVAALLTIIGYSVNDTVVVFDRVRENLRKKTRATLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLKDF 160

                         170       180
                  ....*....|....*....|....*....
gi 1304690525 274 SLTMLIGVSIGTASSIYVASALALKLGMK 302
Cdd:pfam02355 161 SLALLVGVIVGTYSSIFIASPILLDLGER 189
RND_1 NF037998
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ...
 147-224 1.61e-05

protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.


Pssm-ID: 468306  Cd Length: 1237  Bit Score: 46.69  E-value: 1.61e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1304690525  147 AMALMAALLSILVYVGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIREN 224
Cdd:NF037998   960 AISFAIILLALIVYILIRFKWTYYVALALAIVFAPAITVSIVIIFRVPITFEILIAFVSIIGFAIASAIIILGKAKSL 1037
RND_1 NF037998
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ...
 128-305 2.29e-04

protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.


Pssm-ID: 468306  Cd Length: 1237  Bit Score: 42.84  E-value: 2.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  128 VKRIEFVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWRLAAGVVIALAhDVIITLGILSLFHIEIDLTIVASLMSVI 207
Cdd:NF037998   429 VNGISEFNPVVTLLMLIASIIFLLILAIAIMIYLLFAYRLLGLFAIIIALT-SISLTLYSPTWFGLAIGPESITAIFIAI 507

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  208 GYSLNDSIVVSDRIRENFRKIRRGTPyEIFNVSLTQTLhrTLITSGTTLMVILMLYLF--GGPVLEGFSLTMLIGVSIGT 285
Cdd:NF037998   508 GLVLESCSLLFEAFKKHLYKNKRSIE-ESFKIANKETI--GIIVDALVVLLIPNLSLFwiGSNSIKSFATILLVGVIISL 584

                          170       180
                   ....*....|....*....|...
gi 1304690525  286 ASSIYVA---SALALKLGMKREH 305
Cdd:NF037998   585 VLVIIVArlmIWLTIKLQWFKKY 607
 
Name Accession Description Interval E-value
SecF COG0341
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ...
 9-302 1.04e-138

Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440110 [Multi-domain]  Cd Length: 291  Bit Score: 394.03  E-value: 1.04e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525   9 QLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVRGFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNF 88
Cdd:COG0341     1 RLFPGNTNIDFMKKRKIWFAISAVLILASIVSLFTRGLNLGIDFTGGTLIEVSFEQPVDLEEVREALEEAGLGDASVQTF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  89 GSSHDIMVRMPPAEGETGGQVlgSQVLKVINESTNqNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWR 168
Cdd:COG0341    81 GSDNDVLIRTPPLDGESAEEV--EKVRAALKEAFG-DVEIVRVEFVGPTVGKELTRKALLALLVALIGILIYIAFRFEWR 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 169 LAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVSLTQTLHRT 248
Cdd:COG0341   158 FAVGAVVALLHDVLITLGIFSLFGLEFDLTFIAALLTIIGYSLNDTVVVFDRIRENLRKYRKMTLAEIINLSINQTLSRT 237

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1304690525 249 LITSGTTLMVILMLYLFGGPVLEGFSLTMLIGVSIGTASSIYVASALALKLGMK 302
Cdd:COG0341   238 INTSLTTLLVVLALLFFGGETLRDFALALLIGIIVGTYSSIFIASPLLLWLGKR 291
3a0501s07 TIGR00966
protein-export membrane protein SecF; This bacterial protein is always found with the ...
 45-292 9.75e-116

protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273368 [Multi-domain]  Cd Length: 246  Bit Score: 334.24  E-value: 9.75e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  45 GFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNFGSSHDIMVRMPPAEGETGGQVlGSQVLKVINEsTNQ 124
Cdd:TIGR00966   1 GFNFGIDFTGGTVIETRLEQAADVAEVRDVLEKAGIEGVVIQEFGSSHTIMIRIPTLDTEQSEEL-REALEEALKN-VDP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 125 NAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLM 204
Cdd:TIGR00966  79 DAEIRSIDAVGPSVGGELARKAVLALLAALVLILIYITVRFEWRFALGAIVALVHDVIITVGVYSLFGIEVNLTTVAALL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 205 SVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLTMLIGVSIG 284
Cdd:TIGR00966 159 TIIGYSINDTVVVFDRIRENLRKYTRKTFTEVINLSINQTLSRTINTSLTTLLAVLALYVFGGGVIKDFSLALLVGVIVG 238


                  ....*...
gi 1304690525 285 TASSIYVA 292
Cdd:TIGR00966 239 TYSSIFIA 246
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 17-321 1.06e-93

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 294.06  E-value: 1.06e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  17 YDFMRWDYWAFGISGLLLIAAIVIMGVRGFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNFGS-SHDIM 95
Cdd:PRK13024  449 IDFVKKRKWFLIFSIVLVIAGIIIFFIFGLNLGIDFTGGTRYEIRTDQPVDLEQVRADLKELGLGEVNIVTFGSdNNQVL 528

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  96 VRMPPAEgETGGQVLGSQVLKVINESTNQ-NAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWRLAAGVV 174
Cdd:PRK13024  529 VRTYGIL-SDDEEADTEIVAKLKNALKNDkGGTIPSSETVGPTVGKELARNAIIAVLIALIGILLYILIRFEWTFSLGAI 607

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 175 IALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGT 254
Cdd:PRK13024  608 LALLHDVLIVIGFFSLFRLEVDLTFIAAILTIIGYSINDTVVVFDRIRENLRLYKKKDLREIVNKSINQTLSRTINTSLT 687

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1304690525 255 TLMVILMLYLFGGPVLEGFSLTMLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPSI 321
Cdd:PRK13024  688 TLLVLLALLIFGGSSLRNFSLALLVGLIVGTYSSIFIAAPLWLDLEKRRLKKKKKRKKVKKWEVEKI 754
SecD_SecF pfam02355
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ...
 114-302 1.14e-81

Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.


Pssm-ID: 280510 [Multi-domain]  Cd Length: 189  Bit Score: 245.59  E-value: 1.14e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 114 VLKVINESTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWRLAAGVVIALAHDVIITLGILSLFHI 193
Cdd:pfam02355   1 VVEALLKNVGPDAEIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEWRFALGAIIALAHDVIITVGVFSLFGI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 194 EIDLTIVASLMSVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGF 273
Cdd:pfam02355  81 EVDLATVAALLTIIGYSVNDTVVVFDRVRENLRKKTRATLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLKDF 160

                         170       180
                  ....*....|....*....|....*....
gi 1304690525 274 SLTMLIGVSIGTASSIYVASALALKLGMK 302
Cdd:pfam02355 161 SLALLVGVIVGTYSSIFIASPILLDLGER 189
PRK14726 PRK14726
protein translocase subunit SecDF;
19-295 6.58e-76

protein translocase subunit SecDF;


Pssm-ID: 237805 [Multi-domain]  Cd Length: 855  Bit Score: 248.87  E-value: 6.58e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  19 FMRWDYWAFGISGLLLIAAIVIMGVRGFNWGLDFTGGTVIEITLEK-PAEIDVMRDALQKAGFEEPMLQNFGSSHDIMVR 97
Cdd:PRK14726  549 FMGIRRYVFTLSAALSLASLVLFATVGLNLGIDFTGGSLIEVRAKQgNADIADIRARLNELNLGEVQVERFGSPRDALIR 628

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  98 MP-PAEGETGGQvlgSQVLKVINESTNQnAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWRLAAGVVIA 176
Cdd:PRK14726  629 IAsQDGGENAEQ---SAVTLVRGELEDD-YDFRRVEVVGPAVSGELTMAATLGVLAALAAILIYIWIRFEWQFAVGAIIA 704

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 177 LAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTL 256
Cdd:PRK14726  705 TLHDVILTLGLFVLTGIEFNLTSIAAILTIVGYSLNDTVVVYDRVRENLRRYKKMPLPILIDASINQTLSRTVLTSATTL 784

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1304690525 257 MVILMLYLFGGPVLEGFSLTMLIGVSIGTASSIYVASAL 295
Cdd:PRK14726  785 LALLALYLFGGEVIRSFTFAMLFGVAVGTFSSIYIAAPV 823
secF PRK13021
preprotein translocase subunit SecF; Reviewed
 21-305 5.16e-73

preprotein translocase subunit SecF; Reviewed


Pssm-ID: 237274 [Multi-domain]  Cd Length: 297  Bit Score: 227.43  E-value: 5.16e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  21 RWDYWAFGISGLLLIAAIVIMGVRGFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNFGSSHDIMVRMPP 100
Cdd:PRK13021    8 KWRYISSAISIVLMLLSLTIIGVKGFNWGLDFTGGVVTEVQLDRKITSSELQPLLNAAYQQEVSVISASEPGRWVLRYAP 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 101 AEGETGGQVLGSQVLKVINESTNQNAAVkriefVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWRLAAGVVIALAHD 180
Cdd:PRK13021   88 ADTAQSNVDIQQALAPLGTEVQVLNSSI-----VGPQVGQELAEQGGLALLVAMLCILGYLSYRFEWRLASGALFALVHD 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 181 VIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLMVIL 260
Cdd:PRK13021  163 VIFVLAFFALTQMEFNLTVLAAVLAILGYSLNDSIIIADRIRELLIAKPKLAIQEINNQAIVATFSRTMVTSGTTLMTVG 242

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1304690525 261 MLYLFGGPVLEGFSLTMLIGVSIGTASSIYVASALALKLGMKREH 305
Cdd:PRK13021  243 ALWIMGGGPLEGFSIAMFIGILTGTFSSISVGTSLPELLGLSPEH 287
2A0604s01 TIGR00916
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ...
 131-289 1.04e-59

protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273336 [Multi-domain]  Cd Length: 192  Bit Score: 189.78  E-value: 1.04e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 131 IEFVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYS 210
Cdd:TIGR00916  34 VGTVGPTLGGELIKAGIIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHDVILILGVLSLFGATLTLPGIAGLLTIIGYS 113

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1304690525 211 LNDSIVVSDRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLTMLIGVSIGTASSI 289
Cdd:TIGR00916 114 VDDTVVIFDRIREELRKYKGRTFREAINLGINQTLSRIIDTNVTTLLAVLALYVFGGGAIKGFALTLGIGVIAGTYSSI 192
PRK13023 PRK13023
protein translocase subunit SecDF;
19-302 2.35e-44

protein translocase subunit SecDF;


Pssm-ID: 171842 [Multi-domain]  Cd Length: 758  Bit Score: 161.32  E-value: 2.35e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  19 FMRWDYWAFGISGLLLIAAIVIMGVRGFNWGLDFTGGTVIEITLEK-PAEIDVMRDALQKAGFEEPMLQNFGSSHDIMVR 97
Cdd:PRK13023  455 FMRLQFVTLGISVLACAIVVALFVNIGFNYGIDFRGGSMVELQARNgDANLEDINERLAELNIDSARVLPAKSPRSALVI 534

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  98 MppAEGETGGQVLGSQVLKVINEsTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWRLAAGVVIAL 177
Cdd:PRK13023  535 I--GSQEVGDDAEQTVAVKLRGE-FEQDYSFQRVDVVGPTVSEQLSRAGVLAVILSLIGIFIYVWFRFRWQLALGAVLST 611

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 178 AHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLM 257
Cdd:PRK13023  612 LHDVVILSGMFIVFRMEFNLWSVAAILTIIGYSLNDTVVIYDRVRENLRRYKSAPLPAIIDASINQTLSRTLLTSFVTFL 691

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1304690525 258 VILMLYLFGGPVLEGFSLTMLIGVSIGTASSIYVASALALKLGMK 302
Cdd:PRK13023  692 AHVPLYAFGGSEIRMFALALSVGIIVASYSSIFIAAPLLVQFGLK 736
PRK12911 PRK12911
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 17-304 3.51e-41

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 171815 [Multi-domain]  Cd Length: 1403  Bit Score: 153.09  E-value: 3.51e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525   17 YDFMRWDYWAFGISGLLLIAAIVIMGVRGFN--WGLDFTGGTVIEITLEKPAEIDV------MRDALQKAGF--EEPMLQ 86
Cdd:PRK12911  1081 HDFLKECKRLWVVSGSVLVLGCVALGFGAWNsvLGMDFKGGYALTLDPSDVCEYDVeqmrskLRKKFQQIGLssRDFRIR 1160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525   87 NFGSSHDI--------MVRMPPAEG---ETGGQVLgSQVLKVINES----------TNQNAAVKriefVGPSVGADLAQT 145
Cdd:PRK12911  1161 TFDSSEKIkiyfsqnaLDRVEAIEGagsEQSDHHL-ALVLGVLSDTgsdtssevfdATQNFWFK----VSGQLSNKMRTQ 1235

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  146 GAMALMAALLSILVYVGFRFEWRLAAGVVIALAHDVIITLGILSLFH-----IEIDLTIVASLMSVIGYSLNDSIVVSDR 220
Cdd:PRK12911  1236 AVIALFGALGIILLYVSLRFEWRYAFSAICALIHDLLATCAVLVALHfflqkIQIDLQAIGALMTVLGYSLNNTLIIFDR 1315

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  221 IRENfRKIRRGTPYEIF-NVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLTMLIGVSIGTASSIYVASALALKL 299
Cdd:PRK12911  1316 IRED-RQEKLFTPMPILiNDALQKTLGRTVMTTATTLSVLLILLFVGGGSIFNFAFIMTIGILLGTLSSLYIAPPLLLFM 1394


                   ....*
gi 1304690525  300 GMKRE 304
Cdd:PRK12911  1395 VRKEE 1399
PRK08578 PRK08578
preprotein translocase subunit SecF; Reviewed
 32-280 8.67e-19

preprotein translocase subunit SecF; Reviewed


Pssm-ID: 236302 [Multi-domain]  Cd Length: 292  Bit Score: 84.60  E-value: 8.67e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  32 LLLIAAIVIMGVRGFNWGLDFTGGTVIEITLekpaeIDVMRDALQKAGFEEPML-QNFGSSHDIMVRMPPAEGETGGQVl 110
Cdd:PRK08578   28 LLLLGGTFATTGSPVKLGIDFTGGTEITIQT-----NDASPDELESALSGEPGVdVRKGSGNGYIITFGSGDDTDVDKL- 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 111 gSQVLKVINESTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALL--SILVYVGFRfEWRLAAGVVIALAHDVIITLGIL 188
Cdd:PRK08578  102 -ADAVKEFFNVDSISELNYSEKQIGPTFGSQFQEQALKAVGFAFIgmAVVVFLIFR-TPVPSLAVILSAFSDIIIALALM 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 189 SLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIREnfrkiRRGTPYEifnvSLTQTLHRTLITSGTTLMVILMLYL---- 264
Cdd:PRK08578  180 NLFGIELSLATVAALLMLIGYSVDSDILLTTRVLK-----RRGTFDE----SIKRAMRTGITMTLTTIAAMAVLYIvsti 250

                         250
                  ....*....|....*.
gi 1304690525 265 FGGPVLEGFSLTMLIG 280
Cdd:PRK08578  251 PQAEVLANIAAVLIFG 266
secD TIGR01129
protein-export membrane protein SecD; Members of this family are highly variable in length ...
 134-295 8.74e-14

protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273456 [Multi-domain]  Cd Length: 397  Bit Score: 71.16  E-value: 8.74e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 134 VGPSVGADLAQTGAMALMAALLSILVYVGFRFEWrlaAGVV--IALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSL 211
Cdd:TIGR01129 238 IGPSLGADSIEAGIKAGLIGLVLVLVFMILYYRL---FGLIaaIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAV 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 212 NDSIVVSDRIRENFRKIRrgTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLTMLIGVSIGTASSIYV 291
Cdd:TIGR01129 315 DANVLIYERIKEELRLGK--SVRQAIEAGFERAFSTIFDANITTLIAALILYVFGTGPVKGFAVTLAIGIIASLFTALVF 392


                  ....
gi 1304690525 292 ASAL 295
Cdd:TIGR01129 393 TRLL 396
SecD COG0342
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ...
 134-291 1.80e-12

Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440111 [Multi-domain]  Cd Length: 434  Bit Score: 67.45  E-value: 1.80e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 134 VGPSVGADLAQTGAMALMAALLSILVYVGFRF-EWRLAAgvVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLN 212
Cdd:COG0342   261 VGPTLGADSIEKGLIAGLIGLLLVALFMLLYYrLPGLVA--NIALALNVVLLLGVLSLLGATLTLPGIAGIILTIGMAVD 338

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 213 DSIVVSDRIREnfrKIRRGtpyeifnVSLTQTLH-------RTLITS-GTTLMVILMLYLFG-GPVlEGFSLTMLIGVSI 283
Cdd:COG0342   339 ANVLIFERIRE---ELRAG-------RSLRAAIEagfkrafSTILDAnVTTLIAAVVLFVLGtGPV-KGFAVTLILGILI 407


                  ....*...
gi 1304690525 284 GTASSIYV 291
Cdd:COG0342   408 SMFTAVPV 415
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 132-292 8.91e-12

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 66.02  E-value: 8.91e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 132 EFVGPSVGADLAQTGAMA--LMAALLSILVYVGFRFewrlaAGVV--IALAHDVIITLGILSLFHIEIDLTIVASLMSVI 207
Cdd:PRK13024  254 RSVGPTLGQDAIDAGIIAgiIGFALIFLFMLVYYGL-----PGLIanIALLLYIFLTLGALSSLGAVLTLPGIAGLVLGI 328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 208 GYSLNDSIVVSDRIRENFRK-------IRRGtpyeiFNVSLtqtlhRTLITSG-TTLMVILMLYLFG-GPVLeGFSLTML 278
Cdd:PRK13024  329 GMAVDANVLIFERIKEELRKgkslkkaFKKG-----FKNAF-----STILDSNiTTLIAAAILFFFGtGPVK-GFATTLI 397

                         170
                  ....*....|....
gi 1304690525 279 IGVSIGTASSIYVA 292
Cdd:PRK13024  398 IGILASLFTAVFLT 411
secD PRK05812
preprotein translocase subunit SecD; Reviewed
 126-292 3.69e-11

preprotein translocase subunit SecD; Reviewed


Pssm-ID: 235615 [Multi-domain]  Cd Length: 462  Bit Score: 63.71  E-value: 3.69e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 126 AAVKRIE--FVGPSVGADLAQTGAMALMAALLSILVYVGFRFewRLaAGVV--IALAHDVIITLGILSLFHIEIDLTIVA 201
Cdd:PRK05812  277 APLEIVEerTIGPSLGADSIRAGLIAGLIGLALVLLFMILYY--RL-FGLIanIALVANLVLILAVLSLLGATLTLPGIA 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 202 SLMSVIGYSLNDSIVVSDRIREnfrKIRRGtpyeifnVSLTQTLH-------RTLITS-GTTLMVILMLYLFG-GPVlEG 272
Cdd:PRK05812  354 GIVLTIGMAVDANVLIFERIRE---ELREG-------RSLRSAIEagfkrafSTILDSnITTLIAAIILYALGtGPV-KG 422

                         170       180
                  ....*....|....*....|
gi 1304690525 273 FSLTMligvSIGTASSIYVA 292
Cdd:PRK05812  423 FAVTL----GIGILTSMFTA 438
MMPL COG1033
Predicted exporter protein, RND superfamily [General function prediction only];
51-304 3.22e-10

Predicted exporter protein, RND superfamily [General function prediction only];


Pssm-ID: 440656 [Multi-domain]  Cd Length: 767  Bit Score: 61.03  E-value: 3.22e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  51 DFTGGTVIEITLEK-PAEIDVMRDALQKagfeEPMLQNFGSSHD-----IMVRM--PPAEGETGGQVLGSQVLKVINEST 122
Cdd:COG1033   119 GLTVEPLIPDELPAsPEELAELREKVLS----SPLYVGRLVSPDgkatlIVVTLdpDPLSSDLDRKEVVAEIRAIIAKYE 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 123 NQNAavkRIEFVG-PSVGADLAQ------TGAMALMAALLSILVYVGFR-FEWRLAAGVVIALAhdVIITLGILSLFHIE 194
Cdd:COG1033   195 DPGV---EVYLTGfPVLRGDIAEaiqsdlAIFFPLALLLILLLLFLFFRsLRGVLLPLLVVLLA--VIWTLGLMGLLGIP 269

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 195 IDL--TIVASLMSVIGysLNDSIVVSDRIRENFRkiRRGTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEG 272
Cdd:COG1033   270 LSPltILVPPLLLAIG--IDYGIHLLNRYREERR--KGLDKREALREALRKLGPPVLLTSLTTAIGFLSLLFSDIPPIRD 345

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1304690525 273 FSLTMLIGVSIGTASSIYVASALALKLGMKRE 304
Cdd:COG1033   346 FGIVAAIGVLLAFLTSLTLLPALLSLLPRPKP 377
secD PRK08343
preprotein translocase subunit SecD; Reviewed
 128-284 5.18e-10

preprotein translocase subunit SecD; Reviewed


Pssm-ID: 236245 [Multi-domain]  Cd Length: 417  Bit Score: 59.89  E-value: 5.18e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 128 VKRIEFVGPSVGADLAQTGAMALMAALLSILVYVGFRF-EWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSV 206
Cdd:PRK08343  245 IEGSGSVSPSLGEQFKKGSLIAGLLALLAVALVVFLRYrEPRIALPMVITSLSEVIIILGFAALIGWQLDLASIAGIIAV 324

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1304690525 207 IGYSLNDSIVVSDRIRENFRKIRRGtpyeIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLTMLIGVSIG 284
Cdd:PRK08343  325 IGTGVDDLIIITDEVLHEGKVPSRK----VFLSRIKRAFFIIFAAAATTIAAMSPLAVMGLGDLKGFAITTILGVLIG 398
PRK14726 PRK14726
protein translocase subunit SecDF;
134-281 2.34e-09

protein translocase subunit SecDF;


Pssm-ID: 237805 [Multi-domain]  Cd Length: 855  Bit Score: 58.58  E-value: 2.34e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 134 VGPSVGADLAQTGAMA--LMAALLSILVYVGFRFEWRLAagvVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSL 211
Cdd:PRK14726  362 VGPGLGADSIAAGLVAglIAAILVAALMIGFYGFLGVIA---VIALIVNVVLIIAVLSLLGATLTLPGIAGIVLTIGMAV 438

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1304690525 212 NDSIVVSDRIRENFRKIRrgTPYEIFNVSLTQTLhRTLITSGTTLMV--ILMLYLFGGPVlEGFSLTMLIGV 281
Cdd:PRK14726  439 DSNVLIYERIREEEKTGH--SLIQALDRGFSRAL-ATIVDANVTILIaaVILFFLGSGAV-RGFAVTLAVGI 506
PRK13023 PRK13023
protein translocase subunit SecDF;
124-281 1.16e-08

protein translocase subunit SecDF;


Pssm-ID: 171842 [Multi-domain]  Cd Length: 758  Bit Score: 56.16  E-value: 1.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 124 QNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWrLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASL 203
Cdd:PRK13023  258 QAVTVLEERTIASALGEDYASAAVLAALLAALVVGLFMVLSYGI-LGVIALVALVVNIIILTAVLSLIGASISLASIAGL 336

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 204 MSVIGYSLNDSIVVSDRIRENFRKirrgtPYEIFNvSLTQTLHRTLIT----SGTTLMVILMLYLFGGPVLEGFSLTMLI 279
Cdd:PRK13023  337 VLTIGLAVDAHILIYERVREDRRK-----GYSVVQ-AMESGFYRALSTivdaNLTTLIAALVLFLLGSGTVHGFALTVAI 410


                  ..
gi 1304690525 280 GV 281
Cdd:PRK13023  411 GI 412
Sec_GG pfam07549
SecD/SecF GG Motif; This family consists of various prokaryotic SecD and SecF protein export ...
 40-66 9.63e-08

SecD/SecF GG Motif; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force. This alignment encompasses a -GG- motif typically found in N-terminal half of the SecD/SecF proteins.


Pssm-ID: 462205 [Multi-domain]  Cd Length: 27  Bit Score: 47.28  E-value: 9.63e-08
                          10        20
                  ....*....|....*....|....*..
gi 1304690525  40 IMGVRGFNWGLDFTGGTVIEITLEKPA 66
Cdd:pfam07549   1 SLFTRGLNLGLDFTGGTVIELQFDQPV 27
COG4258 COG4258
Predicted exporter [General function prediction only];
150-281 1.20e-07

Predicted exporter [General function prediction only];


Pssm-ID: 443400 [Multi-domain]  Cd Length: 783  Bit Score: 52.93  E-value: 1.20e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 150 LMAALLSILVYVGFR-FEWRLAAGVVIALAHDVIITLGILSLFHIEIDL-TIVASLMsVIGYSLNDSIvvsdrirenFrk 227
Cdd:COG4258   645 LLLALLLILLLLLLRlRSLRRALRVLLPPLLAVLLTLAILGLLGIPLNLfHLIALLL-VLGIGIDYAL---------F-- 712

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1304690525 228 IRRGTPYEifnVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLTMLIGV 281
Cdd:COG4258   713 FTEGLLDK---GELARTLLSILLAALTTLLGFGLLAFSSTPALRSFGLTVLLGI 763
2A067 TIGR00921
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ...
 138-315 1.93e-07

The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273340 [Multi-domain]  Cd Length: 719  Bit Score: 52.53  E-value: 1.93e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 138 VGADLAQTgaMALMAALLSILVYVGFRFEWRLAAGVVIALAhDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVV 217
Cdd:TIGR00921 191 FGKDMGTT--MAISGILVVLVLLLDFKRWWRPLLPLVIILF-GVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQT 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 218 SDRIRENFRKIRrgTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLTMLIGVSIGTASSIYVASALAL 297
Cdd:TIGR00921 268 LNRYEEERDIGR--AKGEAIVTAVRRTGRAVLIALLTTSAGFAALALSEFPMVSEFGLGLVAGLITAYLLTLLVLPALLQ 345

                         170
                  ....*....|....*...
gi 1304690525 298 KLGMKREHMLQQKVEKEG 315
Cdd:TIGR00921 346 SIDIGREKVKKEIIAIGG 363
RND_1 NF037998
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ...
 147-224 1.61e-05

protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.


Pssm-ID: 468306  Cd Length: 1237  Bit Score: 46.69  E-value: 1.61e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1304690525  147 AMALMAALLSILVYVGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIREN 224
Cdd:NF037998   960 AISFAIILLALIVYILIRFKWTYYVALALAIVFAPAITVSIVIIFRVPITFEILIAFVSIIGFAIASAIIILGKAKSL 1037
RND_1 NF037998
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ...
 128-305 2.29e-04

protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.


Pssm-ID: 468306  Cd Length: 1237  Bit Score: 42.84  E-value: 2.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  128 VKRIEFVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWRLAAGVVIALAhDVIITLGILSLFHIEIDLTIVASLMSVI 207
Cdd:NF037998   429 VNGISEFNPVVTLLMLIASIIFLLILAIAIMIYLLFAYRLLGLFAIIIALT-SISLTLYSPTWFGLAIGPESITAIFIAI 507

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  208 GYSLNDSIVVSDRIRENFRKIRRGTPyEIFNVSLTQTLhrTLITSGTTLMVILMLYLF--GGPVLEGFSLTMLIGVSIGT 285
Cdd:NF037998   508 GLVLESCSLLFEAFKKHLYKNKRSIE-ESFKIANKETI--GIIVDALVVLLIPNLSLFwiGSNSIKSFATILLVGVIISL 584

                          170       180
                   ....*....|....*....|...
gi 1304690525  286 ASSIYVA---SALALKLGMKREH 305
Cdd:NF037998   585 VLVIIVArlmIWLTIKLQWFKKY 607
PRK12911 PRK12911
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 132-292 2.42e-04

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 171815 [Multi-domain]  Cd Length: 1403  Bit Score: 42.92  E-value: 2.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  132 EFVGPSVGADLAQTGAMA--LMAALLSILVYVGFRFEWRLAAGVVIAlahDVIITLGILSLFHIEIDLTIVASLMSVIGY 209
Cdd:PRK12911   897 EVISPELGKSQRTQGIISvcLGLAVLIVLMSVYYRFGGVIASGAVLL---NLLLIWAALQYLDAPLTLSGLAGIVLAMGM 973

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525  210 SLNDSIVVSDRIRENFRKIRRGTP-----YE-----IFNVSLTqtlhrtlitsgTTLMVILMLYLFGGPVlEGFSLTMLI 279
Cdd:PRK12911   974 AVDANVLVFERIREEYLLSRSLSEsveagYKkafsaIFDSNLT-----------TILASALLLMLDTGPI-KGFALTLII 1041

                          170
                   ....*....|...
gi 1304690525  280 GVsigtASSIYVA 292
Cdd:PRK12911  1042 GI----FSSMFTA 1050
secD PRK12933
protein translocase subunit SecD;
134-295 7.80e-04

protein translocase subunit SecD;


Pssm-ID: 183831 [Multi-domain]  Cd Length: 604  Bit Score: 41.21  E-value: 7.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 134 VGPSVGADLAQTGAMALMAALLSILVYVGFrfeW--RLAAGVVIALAHDVIITLGILSLFHIEIdLTI--VASLMSVIGY 209
Cdd:PRK12933  430 IGPSLGAENIENGFAALALGMGITLLFMAL---WyrRLGWVANVALIANMVCLFGLLALIPGAV-LTLpgIAGLVLTVGM 505

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1304690525 210 SLNDSIVVSDRIREnfrKIRRGTpyeifnvSLTQTLHR-------TLITSG-TTLMVILMLYLFG-GPVlEGFSLTMLIG 280
Cdd:PRK12933  506 AVDTNVLIFERIKD---KLKEGR-------SFAQAIDTgfdsafsTIFDANfTTMITAVVLYSIGnGPI-QGFALTLGLG 574

                         170
                  ....*....|....*
gi 1304690525 281 VSIGTASSIYVASAL 295
Cdd:PRK12933  575 LLTSMFTGIFASRAL 589
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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