|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
47-654 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 755.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 47 AVPQTSVFYANDDTVIGQNNEmQKRYNVSLNEISPYVKEATLSIEDQRFYKHHGFDMKRIAGAIVADLKAMAKVQGASTI 126
Cdd:COG0744 51 ALPQTSTIYDRDGTLIATLGD-ENREWVPLDQIPPHLKDAVVAIEDRRFYEHGGVDPKGIARALVANLTAGGVVQGGSTI 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 127 TQQYARNLYLDHDKTWKRKLLEAMYTVRLEVNYNKNHILEGYLNTIYYGHGAYGIEAASRLYFDKTAKELTLAEASMLAG 206
Cdd:COG0744 130 TQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAG 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 207 IPKGPSVYSPFLKEDRAKGRQALILDEMVEQGYITKQQAALAKKEPLTFASLDTKKVAEVAPYFQDAVQASLLRDVGldE 286
Cdd:COG0744 210 LVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEADAAKAEPLTLVPPPNGAAAGKYPYFVDYVRRELEELLG--E 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 287 QALQRGGLRIYTTLDPKLQAVAEQAVKDYIPDTT--NIQTALVSMNPTTGEVAALVGGTDYNMSQFNRATQAVRQPGSTF 364
Cdd:COG0744 288 DDLYRGGLKIYTTLDPKLQKAAEKAVKNVLPEGKpgGLQAALVVVDPKTGEVLAMVGGRDYGKSQFNRATQAKRQPGSTF 367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 365 KPFLYYAALERGFTPATRLKSEYTVFTLGDgvskYKPKNYKDYYADDfVTMAQALAVSDNIYAVKTNLFLGDDALAKTAK 444
Cdd:COG0744 368 KPFVYAAALEQGYTPATTVDDEPVTFPGGG----WSPKNYDGRYRGP-VTLREALANSLNTPAVRLAQEVGLDKVVDTAR 442
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 445 QFGIKSALKDVPSLALGTSPVKPIEMVNAYSMFANGGKEVKPTFIRRIMDHEGNILYDAHLESKQVLDKSKAFVMEEMMT 524
Cdd:COG0744 443 RLGITSPLDPNPSLALGTSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYLMTDMLQ 522
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 525 GMFNKKLSSYAAVTGqsmlsklsRTYAGKSGSTE--TDSWMIGFTPQIVTGVWVGYDQPKSISNVAEQGYAKKIWTDTME 602
Cdd:COG0744 523 DVVTSGTGRAARLPG--------RPVAGKTGTTNdnRDAWFVGYTPQLVTAVWVGNDDNSPMGYVTGGSLPAPIWRDFME 594
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|..
gi 1264778634 603 KGLDGQPKKEFKQPSDVVAVNINPENgkiatkncpisvkmyfAKGTEPTEYC 654
Cdd:COG0744 595 AALEGLPVEDFPKPSGVVRIDEPSPT----------------PSGTEPTETS 630
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
70-605 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 630.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 70 KRYNVSLNEISPYVKEATLSIEDQRFYKHHGFDMKRIAGAIVADLKAMAKVQGASTITQQYARNLYLDHDKTWKRKLLEA 149
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 150 MYTVRLEVNYNKNHILEGYLNTIYYGHGAYGIEAASRLYFDKTAKELTLAEASMLAGIPKGPSVYSPFLKEDRAKGRQAL 229
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 230 ILDEMVEQGYITKQQAALAKKEPLTfASLDTKKVAEV-APYFQDAVQASLLRDVGLDeqaLQRGGLRIYTTLDPKLQAVA 308
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQ-LYLQTKKSEQYkAPYFVDYVIQELEEEYGEE---LYTGGLKIYTTLDLDAQKAA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 309 EQAVKD--YIPDT---TNIQTALVSMNPTTGEVAALVGGTDYNMSQFNRATQAVRQPGSTFKPFLYYAALERGFTPATRL 383
Cdd:TIGR02074 237 EKVLNTglRVAGRrdgDDLQAALVAIDPDTGAVRALVGGRDYGKSQFNRATQAKRQPGSTFKPFVYAAALEKGLTPATIV 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 384 KSEYTVFtlgDGVSKYKPKNYKDYYAdDFVTMAQALAVSDNIYAVKTNLFLGDDALAKTAKQFGIKSALKDVPSLALGTS 463
Cdd:TIGR02074 317 NDEPITY---NGNGPWSPKNYGGGYR-GNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITSPLDPVLSLALGTV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 464 PVKPIEMVNAYSMFANGGKEVKPTFIRRIMDHEGNILYDAHLESKQVLDKSKAFVMEEMMTGMFNKKLSSYAAVTGqsml 543
Cdd:TIGR02074 393 EVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGRSARLPG---- 468
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1264778634 544 sklsRTYAGKSGSTET--DSWMIGFTPQIVTGVWVGYDQPKSISN-VAEQGYAKKIWTDTMEKGL 605
Cdd:TIGR02074 469 ----RPVAGKTGTTQNwrDAWFVGYTPYYVTAVWVGYDDKKTLGKsGTGGGLAAPIWRDFMAEAL 529
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
55-653 |
1.64e-107 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 345.58 E-value: 1.64e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 55 YANDDTVIGQNNEmQKRYNVSLNEISPYVKEATLSIEDQRFYKHHGFDMKRIAGAIVADLKAMAKVQGASTITQQYARNL 134
Cdd:PRK11636 51 YSADGELIAQYGE-KRRIPLTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNF 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 135 YLDHDKTWKRKLLEAMYTVRLEVNYNKNHILEGYLNTIYYGHGAYGIEAASRLYFDKTAKELTLAEASMLAGIPKGPSVY 214
Cdd:PRK11636 130 FLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTF 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 215 SPFLKEDRAKGRQALILDEMVEQGYITKQQAALAKKEPLTfASLDTKKVAEVAPYFQDAVQASLLRDVGldEQALQrGGL 294
Cdd:PRK11636 210 NPLYSMDRAVARRNVVLSRMLDEGYITQAQYDQARSEPIV-ANYHAPEIAFSAPYLSEMVRQEMYNRYG--ENAYE-DGY 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 295 RIYTTLDPKLQAVAEQAVKD------------------------------------------------------------ 314
Cdd:PRK11636 286 RVYTTITRKVQQAAQQAVRNnvldydmrhgyrgpanvlwkvgesawdnkkitdtlkalptygpllpavvtsanpqeatam 365
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 315 -------------------YIPDTT---------------------------------NIQTALVSMNPTTGEVAALVGG 342
Cdd:PRK11636 366 ladgssvalpmegvrwarpYRSDTQqgptprkvtdvvqtgqqiwvrqvddawwlaqvpDVNSALVSINPQNGAVMALVGG 445
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 343 TDYNMSQFNRATQAVRQPGSTFKPFLYYAALERGFTPATRLKS-EYTVFTLGDGvSKYKPKNYKDYYADDfVTMAQALAV 421
Cdd:PRK11636 446 FDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGLTLASMLNDvPISRWDAGAG-SDWRPKNSPPQYAGP-IRLRQGLGQ 523
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 422 SDNIYAVKTNLFLGDDALAKTAKQFGIKSA-LKDVPSLALGTSPVKPIEMVNAYSMFANGGKEVKPTFIRRIMDHEGNIL 500
Cdd:PRK11636 524 SKNVVMVRAMRAMGVDYAAEYLQRFGFPAQnIVHTESLALGSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVI 603
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 501 YDAHleSKQVL----------DKSKAFVMEEmmTGMFNKKLSSYAAVTGQSM--LSKLSRT---------YA-------- 551
Cdd:PRK11636 604 FEAK--PKVACpecdipviygDTQKSNVLEN--DDVENVATSQEQQNSSVPMpqLEQANQAlvaqngaqeYAphvintpl 679
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 552 -----------------------------------GKSGSTET--DSWMIGFTPQIVTGVWVGYDQ-------------- 580
Cdd:PRK11636 680 afliksalntnifgepgwmgtgwragrdlkrrdigGKTGTTNSskDAWFSGYGPGVVTSVWIGFDDhrrdlgrttasgai 759
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1264778634 581 PKSISNvAEQG--YAKKIWTDTMEKGLDGQPKKEFKQPSDVVAVNINPENGKIAtkNCPISVKMYFAKGTEPTEY 653
Cdd:PRK11636 760 KDQISG-YEGGakSAQPAWDDYMKAALEGVPEQPLTPPPGIVTVNIDRSTGKLA--NGGNSREEYFIEGTQPTQQ 831
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
58-235 |
1.01e-83 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 261.69 E-value: 1.01e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 58 DDTVIGQNNEmQKRYNVSLNEISPYVKEATLSIEDQRFYKHHGFDMKRIAGAIVADLKAMAKVQGASTITQQYARNLYLD 137
Cdd:pfam00912 1 DGTLLAELGE-ENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 138 HDKTWKRKLLEAMYTVRLEVNYNKNHILEGYLNTIYYGHGAYGIEAASRLYFDKTAKELTLAEASMLAGIPKGPSVYSPF 217
Cdd:pfam00912 80 PERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPL 159
|
170
....*....|....*...
gi 1264778634 218 LKEDRAKGRQALILDEMV 235
Cdd:pfam00912 160 RNPERAKRRRNLVLDRMV 177
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
47-654 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 755.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 47 AVPQTSVFYANDDTVIGQNNEmQKRYNVSLNEISPYVKEATLSIEDQRFYKHHGFDMKRIAGAIVADLKAMAKVQGASTI 126
Cdd:COG0744 51 ALPQTSTIYDRDGTLIATLGD-ENREWVPLDQIPPHLKDAVVAIEDRRFYEHGGVDPKGIARALVANLTAGGVVQGGSTI 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 127 TQQYARNLYLDHDKTWKRKLLEAMYTVRLEVNYNKNHILEGYLNTIYYGHGAYGIEAASRLYFDKTAKELTLAEASMLAG 206
Cdd:COG0744 130 TQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAG 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 207 IPKGPSVYSPFLKEDRAKGRQALILDEMVEQGYITKQQAALAKKEPLTFASLDTKKVAEVAPYFQDAVQASLLRDVGldE 286
Cdd:COG0744 210 LVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEADAAKAEPLTLVPPPNGAAAGKYPYFVDYVRRELEELLG--E 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 287 QALQRGGLRIYTTLDPKLQAVAEQAVKDYIPDTT--NIQTALVSMNPTTGEVAALVGGTDYNMSQFNRATQAVRQPGSTF 364
Cdd:COG0744 288 DDLYRGGLKIYTTLDPKLQKAAEKAVKNVLPEGKpgGLQAALVVVDPKTGEVLAMVGGRDYGKSQFNRATQAKRQPGSTF 367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 365 KPFLYYAALERGFTPATRLKSEYTVFTLGDgvskYKPKNYKDYYADDfVTMAQALAVSDNIYAVKTNLFLGDDALAKTAK 444
Cdd:COG0744 368 KPFVYAAALEQGYTPATTVDDEPVTFPGGG----WSPKNYDGRYRGP-VTLREALANSLNTPAVRLAQEVGLDKVVDTAR 442
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 445 QFGIKSALKDVPSLALGTSPVKPIEMVNAYSMFANGGKEVKPTFIRRIMDHEGNILYDAHLESKQVLDKSKAFVMEEMMT 524
Cdd:COG0744 443 RLGITSPLDPNPSLALGTSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYLMTDMLQ 522
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 525 GMFNKKLSSYAAVTGqsmlsklsRTYAGKSGSTE--TDSWMIGFTPQIVTGVWVGYDQPKSISNVAEQGYAKKIWTDTME 602
Cdd:COG0744 523 DVVTSGTGRAARLPG--------RPVAGKTGTTNdnRDAWFVGYTPQLVTAVWVGNDDNSPMGYVTGGSLPAPIWRDFME 594
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|..
gi 1264778634 603 KGLDGQPKKEFKQPSDVVAVNINPENgkiatkncpisvkmyfAKGTEPTEYC 654
Cdd:COG0744 595 AALEGLPVEDFPKPSGVVRIDEPSPT----------------PSGTEPTETS 630
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
49-654 |
0e+00 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 662.63 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 49 PQTSVFYANDDTVIGQNNEmQKRYNVSLNEISPYVKEATLSIEDQRFYKHHGFDMKRIAGAIVADLKAMAKVQGASTITQ 128
Cdd:COG5009 45 PTPSRVYSADGKLIAEFGE-ERRIPVPIEEIPPLLINAFLAAEDKRFYEHPGVDPIGIARAAVVNLRTGRRVQGGSTITQ 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 129 QYARNLYLDHDKTWKRKLLEAMYTVRLEVNYNKNHILEGYLNTIYYGHGAYGIEAASRLYFDKTAKELTLAEASMLAGIP 208
Cdd:COG5009 124 QVAKNFLLSPERTLTRKIKEAILALRIEQELSKDEILELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLP 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 209 KGPSVYSPFLKEDRAKGRQALILDEMVEQGYITKQQAALAKKEPLTfASLDTKKVAEVAPYFQDAVQASLLRDVGldEQA 288
Cdd:COG5009 204 KAPSRYNPIRNPERALERRNYVLGRMLELGYITQAEYEAAKAEPLT-ARYHGASAEVDAPYFAEMVRRELVERYG--EDA 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 289 LQRGGLRIYTTLDPKLQAVAEQAVKD------------------------------------------------------ 314
Cdd:COG5009 281 LYTGGLKVYTTLDPRLQEAAEKALRDgllaydrrhgyrgpeahldlaeedwdealaevpdvgdlrpavvlevddksarvg 360
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 315 -------------------YIPDTTN----------------------------------IQTALVSMNPTTGEVAALVG 341
Cdd:COG5009 361 lrdgetgtlpleglkwarpYINDNRRgpapksasdvlkpgdvirvrpvadggwrlrqipeVQGALVALDPHTGAVLALVG 440
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 342 GTDYNMSQFNRATQAVRQPGSTFKPFLYYAALERGFTPATRLKSEYTVFTLGDGVSKYKPKNY-KDYYAddFVTMAQALA 420
Cdd:COG5009 441 GFDFEQSKFNRATQAKRQPGSSFKPFVYAAALDNGYTPATIINDAPIVFDDGGGGGVWRPKNYsGKFYG--PTTLREALE 518
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 421 VSDNIYAVKTNLFLGDDALAKTAKQFGIKSALKDVPSLALGTSPVKPIEMVNAYSMFANGGKEVKPTFIRRIMDHEGNIL 500
Cdd:COG5009 519 KSRNLVTVRLLQDVGIDYVIDYAERFGIYSKLPPNLSLALGSGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVI 598
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 501 YDA---------------------HLESKQVLDKSKAFVMEEMMTGmfnkklssyaAV---TGQSMLSkLSRTYAGKSGS 556
Cdd:COG5009 599 YRAdparacedcdaaewdgaeprlPDPAEQVIDPRTAYQMTSMLRG----------VVqrgTGRRARA-LGRDIAGKTGT 667
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 557 T--ETDSWMIGFTPQIVTGVWVGYDQPKSISNvAEQG--YAKKIWTDTMEKGLDGQPKKEFKQPSDVVAVNINPENGKIA 632
Cdd:COG5009 668 TndSKDAWFVGFTPDLVAGVWVGFDDPRSLGR-GETGgrAALPIWIDFMKAALKDKPEKPFPVPEGIVTVRIDPKTGLLA 746
|
730 740
....*....|....*....|..
gi 1264778634 633 TKNCPISVKMYFAKGTEPTEYC 654
Cdd:COG5009 747 SPGDPDAIFEAFKPGTEPTESA 768
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
70-605 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 630.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 70 KRYNVSLNEISPYVKEATLSIEDQRFYKHHGFDMKRIAGAIVADLKAMAKVQGASTITQQYARNLYLDHDKTWKRKLLEA 149
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 150 MYTVRLEVNYNKNHILEGYLNTIYYGHGAYGIEAASRLYFDKTAKELTLAEASMLAGIPKGPSVYSPFLKEDRAKGRQAL 229
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 230 ILDEMVEQGYITKQQAALAKKEPLTfASLDTKKVAEV-APYFQDAVQASLLRDVGLDeqaLQRGGLRIYTTLDPKLQAVA 308
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQ-LYLQTKKSEQYkAPYFVDYVIQELEEEYGEE---LYTGGLKIYTTLDLDAQKAA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 309 EQAVKD--YIPDT---TNIQTALVSMNPTTGEVAALVGGTDYNMSQFNRATQAVRQPGSTFKPFLYYAALERGFTPATRL 383
Cdd:TIGR02074 237 EKVLNTglRVAGRrdgDDLQAALVAIDPDTGAVRALVGGRDYGKSQFNRATQAKRQPGSTFKPFVYAAALEKGLTPATIV 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 384 KSEYTVFtlgDGVSKYKPKNYKDYYAdDFVTMAQALAVSDNIYAVKTNLFLGDDALAKTAKQFGIKSALKDVPSLALGTS 463
Cdd:TIGR02074 317 NDEPITY---NGNGPWSPKNYGGGYR-GNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITSPLDPVLSLALGTV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 464 PVKPIEMVNAYSMFANGGKEVKPTFIRRIMDHEGNILYDAHLESKQVLDKSKAFVMEEMMTGMFNKKLSSYAAVTGqsml 543
Cdd:TIGR02074 393 EVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGRSARLPG---- 468
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1264778634 544 sklsRTYAGKSGSTET--DSWMIGFTPQIVTGVWVGYDQPKSISN-VAEQGYAKKIWTDTMEKGL 605
Cdd:TIGR02074 469 ----RPVAGKTGTTQNwrDAWFVGYTPYYVTAVWVGYDDKKTLGKsGTGGGLAAPIWRDFMAEAL 529
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
5-657 |
1.51e-115 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 364.54 E-value: 1.51e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 5 MNPKLKKYKRLFFTAMFSCVLFFVFSFFIIIIvakimgPPPV--AVPQTSVFYANDDTVIGQ--NNEMQKRYNVSLNEIS 80
Cdd:COG4953 1 MKRARLRRRRLLALLLALLLLALALWALDRLF------PLPLlfAVPYSTVVLDRDGTLLRAflAADGQWRLPVPLDEVS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 81 PYVKEATLSIEDQRFYKHHGFDMKRIAGAIVADLKAMAKVQGASTITQQYARNLYlDHDKTWKRKLLEAMYTVRLEVNYN 160
Cdd:COG4953 75 PRYLQALLAYEDRRFYYHPGVNPLALLRAAWQNLRSGRIVSGGSTLTMQVARLLE-PRPRTLSGKLRQILRALQLERRYS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 161 KNHILEGYLNTIYYGHGAYGIEAASRLYFDKTAKELTLAEASMLAGIPKGPSVYSPFLKEDRAKGRQALILDEMVEQGYI 240
Cdd:COG4953 154 KDEILELYLNLAPYGGNIEGVEAASLAYFGKPPSRLSLAEAALLAVLPQAPSRRRPDRNPERARAARDRVLARLAEAGVI 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 241 TKQQAALAKKEPLTFASLDTKKvaeVAPYFQDAVQASllrdvgldeqalQRGGLRIYTTLDPKLQAVAEQAVKDYI---- 316
Cdd:COG4953 234 DAEEAALALLEPVPARRRPLPQ---LAPHLARRLLRQ------------LPGGTRIRTTLDAGLQRRLERLVRRYVrrlk 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 317 -PDTTNIqtALVSMNPTTGEVAALVGGTDYnmsqFNRA-------TQAVRQPGSTFKPFLYYAALERGF-TPATRLKSEY 387
Cdd:COG4953 299 qNGIHNA--AVLVVDNRTGEVLAYVGSADF----FDASrqgqvdmVRALRSPGSTLKPFLYGLALDQGLiHPETLLADVP 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 388 TVFtlGDgvskYKPKNY-KDYYADdfVTMAQALAVSDNIYAVKTNLFLGDDALAKTAKQFGIKSALK--DVP--SLALGT 462
Cdd:COG4953 373 TSF--GG----YRPENFdGTFQGP--VSAREALARSLNIPAVRLLEALGPARFYARLRRAGLRLLLPpaEHYglSLILGG 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 463 SPVKPIEMVNAYSMFANGGKEVKPTFIRRimdhegnilyDAHLESKQVLDKSKAFVMEEMMTG------MFNKKLSSyaa 536
Cdd:COG4953 445 AEVTLEELVGLYAALARGGEARPLRLLAG----------EPASPGRRLLSPGAAWLVRDILSDvprpdgAFGWRALD--- 511
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 537 vtgqsmlskLSRTYAGKSGsteT-----DSWMIGFTPQIVTGVWVGydQPKSISNVAEQGY--AKKIWTDTMEKGLDGQP 609
Cdd:COG4953 512 ---------SPPPIAWKTG---TsygfrDAWAVGFTGRYTVGVWVG--NPDGTPVPGLTGAeaAAPLLFDIFDLLPASRW 577
|
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 1264778634 610 KKEFKQPSDVVAVNINPENGKIATKNCPISVKMYFAKGTEPTEYCMDH 657
Cdd:COG4953 578 PLPFPPPAGLLRVEVCAPSGLLAGPNCPQRVTEWFIPGTSPPTLCPYH 625
|
|
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
63-650 |
7.22e-113 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 356.34 E-value: 7.22e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 63 GQNNEmqKRYNVSLNEISPYVKEATLSIEDQRFYKHHGFDMKRIAGAIVADLKAMAKVQGASTITQQYARNLYLDHDKTW 142
Cdd:TIGR02071 141 SPNGE--QRLFVPRDQFPELLVDTLLATEDRDFYEHDGISLYSIGRAVWVNLTAGRTVQGGSTLTQQLVKNLFLSNERSL 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 143 KRKLLEAMYTVRLEVNYNKNHILEGYLNTIYYGH-GA---YGIEAASRLYFDKTAKELTLAEASMLAGIPKGPSVYSPFL 218
Cdd:TIGR02071 219 WRKANEAYMALILDARYSKDRILELYLNEVYLGQsGDdaiHGFPLASQYYFGRPLGELSLDQVALLVGMVKGPSYYNPWR 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 219 KEDRAKGRQALILDEMVEQGYITKQQAALAKKEPltfasLDTKKVAEVA---PYFQDAVQASLLRDVGldEQALQRGGLR 295
Cdd:TIGR02071 299 NPDRALERRNLVLRLLQEQKIIDDEEYDMLSARP-----LGVQKKGGIIsrqPAFLQLVRRELRQKLG--DKVKDLSGLR 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 296 IYTTLDPKLQAVAEQAVKDYIP------DTTNIQTALVSMNPTTGEVAALVGGTDYNMSQFNRATQAVRQPGSTFKPFLY 369
Cdd:TIGR02071 372 IFTTLDPVSQSAAEQAVQETIPalkkkkKLPDLEAAMVVTDRFTGEVRAMVGGSDPQFAGFNRALQARRQIGSLVKPAVY 451
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 370 YAALER--GFTPATRLkSEYTVFTLGDGVSKYKPKNYKDYYADDfVTMAQALAVSDNIYAVKTNLFLGDDALAKTAKQFG 447
Cdd:TIGR02071 452 LTALSQpdKYRLNTWI-EDQPLSIKLSNGQVWSPQNYDRRYSGT-VMLYDALAHSLNIPTVNLGMKVGLPKVSQTWNKLG 529
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 448 I-KSALKDVPSLALGTSPVKPIEMVNAYSMFANGGKEVKPTFIRRIMDHEGNILYDAHLESKQVLDKSKAFVMEEMMTGM 526
Cdd:TIGR02071 530 InKDEIPPVPSMLLGAINLTPYEVAQLYQTIASGGNRAPLSAVRSVLDEDGKVLYQSDPQAEQAVPSQAAYLTLYAMQQV 609
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 527 FNKKlssyaavTGQSMLSKLSR-TYAGKSGSTET--DSWMIGFTPQIVTGVWVGYDQPKSISNVAEQGyAKKIWTDTMEK 603
Cdd:TIGR02071 610 VQRG-------TARSLGADFPSlSLAGKTGTTNDnrDSWFAGIDGKEVTIIWLGRDDNGPTKLTGASG-ALQVYARYLSY 681
|
570 580 590 600
....*....|....*....|....*....|....*....|....*...
gi 1264778634 604 gldGQPKK-EFKQPSDVVAVNINPENGKIATKNCPISVKMYFAKGTEP 650
Cdd:TIGR02071 682 ---QTPEPlLLVPPEGIDWFGVDPQGNGGCKANCPGARRLPIWTGNPQ 726
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
55-653 |
1.64e-107 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 345.58 E-value: 1.64e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 55 YANDDTVIGQNNEmQKRYNVSLNEISPYVKEATLSIEDQRFYKHHGFDMKRIAGAIVADLKAMAKVQGASTITQQYARNL 134
Cdd:PRK11636 51 YSADGELIAQYGE-KRRIPLTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNF 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 135 YLDHDKTWKRKLLEAMYTVRLEVNYNKNHILEGYLNTIYYGHGAYGIEAASRLYFDKTAKELTLAEASMLAGIPKGPSVY 214
Cdd:PRK11636 130 FLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTF 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 215 SPFLKEDRAKGRQALILDEMVEQGYITKQQAALAKKEPLTfASLDTKKVAEVAPYFQDAVQASLLRDVGldEQALQrGGL 294
Cdd:PRK11636 210 NPLYSMDRAVARRNVVLSRMLDEGYITQAQYDQARSEPIV-ANYHAPEIAFSAPYLSEMVRQEMYNRYG--ENAYE-DGY 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 295 RIYTTLDPKLQAVAEQAVKD------------------------------------------------------------ 314
Cdd:PRK11636 286 RVYTTITRKVQQAAQQAVRNnvldydmrhgyrgpanvlwkvgesawdnkkitdtlkalptygpllpavvtsanpqeatam 365
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 315 -------------------YIPDTT---------------------------------NIQTALVSMNPTTGEVAALVGG 342
Cdd:PRK11636 366 ladgssvalpmegvrwarpYRSDTQqgptprkvtdvvqtgqqiwvrqvddawwlaqvpDVNSALVSINPQNGAVMALVGG 445
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 343 TDYNMSQFNRATQAVRQPGSTFKPFLYYAALERGFTPATRLKS-EYTVFTLGDGvSKYKPKNYKDYYADDfVTMAQALAV 421
Cdd:PRK11636 446 FDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGLTLASMLNDvPISRWDAGAG-SDWRPKNSPPQYAGP-IRLRQGLGQ 523
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 422 SDNIYAVKTNLFLGDDALAKTAKQFGIKSA-LKDVPSLALGTSPVKPIEMVNAYSMFANGGKEVKPTFIRRIMDHEGNIL 500
Cdd:PRK11636 524 SKNVVMVRAMRAMGVDYAAEYLQRFGFPAQnIVHTESLALGSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVI 603
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 501 YDAHleSKQVL----------DKSKAFVMEEmmTGMFNKKLSSYAAVTGQSM--LSKLSRT---------YA-------- 551
Cdd:PRK11636 604 FEAK--PKVACpecdipviygDTQKSNVLEN--DDVENVATSQEQQNSSVPMpqLEQANQAlvaqngaqeYAphvintpl 679
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 552 -----------------------------------GKSGSTET--DSWMIGFTPQIVTGVWVGYDQ-------------- 580
Cdd:PRK11636 680 afliksalntnifgepgwmgtgwragrdlkrrdigGKTGTTNSskDAWFSGYGPGVVTSVWIGFDDhrrdlgrttasgai 759
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1264778634 581 PKSISNvAEQG--YAKKIWTDTMEKGLDGQPKKEFKQPSDVVAVNINPENGKIAtkNCPISVKMYFAKGTEPTEY 653
Cdd:PRK11636 760 KDQISG-YEGGakSAQPAWDDYMKAALEGVPEQPLTPPPGIVTVNIDRSTGKLA--NGGNSREEYFIEGTQPTQQ 831
|
|
| PBP_1c |
TIGR02073 |
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ... |
43-657 |
8.84e-93 |
|
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273954 [Multi-domain] Cd Length: 727 Bit Score: 303.19 E-value: 8.84e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 43 PPPV--AVPQTSVFYANDDTVIGQ--NNEMQKRYNVSLNEISPYVKEATLSIEDQRFYKHHGFDMKRIAGAIVADLKAMA 118
Cdd:TIGR02073 1 PPPLlfHRPSSTVVLDRHGTLLRAllANDGQWRLPVPLEDISPKFLQALLLYEDKRFYWHPGVNPLALLRAAWQNLTNGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 119 KVQGASTITQQYARNLYLDHDKTWKRKLLEAMYTVRLEVNYNKNHILEGYLNTIYYGHGAYGIEAASRLYFDKTAKELTL 198
Cdd:TIGR02073 81 RVSGGSTLTMQLARLLDPELSRTLTGKLRQMWRAIQLEARYSKREILEAYLNLAPYGGNLEGLRAASLIYFGKEPSSLSL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 199 AEASMLAGIPKGPSVYSPFLKEDRAKGRQALILDEMVEQGYITKQQAALAKKEPLtfasLDTKKVAEV-APYFQDAVQas 277
Cdd:TIGR02073 161 AEAALLAALPQAPSARRLDRLPKAAKAARDRLLDRMVEQGPDDSEQVALAALEPL----PALPEPLPQlAPHFALKLL-- 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 278 llrdvgldeQALQRGGLRIYTTLDPKLQAVAEQAVKDYI---PDTTNIQTALVSMNPTTGEVAALVGGTDY-NMSQFNR- 352
Cdd:TIGR02073 235 ---------RARPEIASVIVSTLDADLQRRLEELARRYLsalRPRGISNLAILVVDNRSGAVLAYVGSADFfDDSNSGQv 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 353 -ATQAVRQPGSTFKPFLYYAALERGF-TPATRLKSEYTVFtlgdgvSKYKPKNYKDYYADDfVTMAQALAVSDNIYAVKT 430
Cdd:TIGR02073 306 dGVRAPRSPGSTLKPFLYALALDDGLlHPDSLLKDVPLRF------GDYAPENFDKTFHGP-VPAREALARSLNIPAVRL 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 431 NLFLGDDALAKTAKQFGIKSALK--DVP--SLALGTSPVKPIEMVNAYSMFANGGKEVKPTFIRRImdhegnilyDAHLE 506
Cdd:TIGR02073 379 LERVGPPRFADFLRQAGLNLLKPksDYYglSLALGGAEITLQDLANLYAMLANQGLSGPLRFLQTD---------AKRPE 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 507 SKQVLDKSKAFVMEEMMTGMFNKKLSSYAAVTGQSMlsklsrTYAGKSGSTE--TDSWMIGFTPQIVTGVWVGYDQPKSI 584
Cdd:TIGR02073 450 RERLLSPGAAWIVLDILKDRPRPDDTLPLSALPTRL------PLAWKTGTSYgfRDAWAAGVSGRYTIGVWVGNFDGKPN 523
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1264778634 585 SNVAEQGYAKKIWTDTMEKGLDGQPkkeFKQPSDVVAVNINPENGKIATKNCPISVKMYFAKGTEPTEYCMDH 657
Cdd:TIGR02073 524 PGFFGAAAAAPLLFDILDALQASEA---STLPRPLKEVPGCLVLGNLPILPCPEQISTWFLPGGSPPTLSEPH 593
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
58-235 |
1.01e-83 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 261.69 E-value: 1.01e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 58 DDTVIGQNNEmQKRYNVSLNEISPYVKEATLSIEDQRFYKHHGFDMKRIAGAIVADLKAMAKVQGASTITQQYARNLYLD 137
Cdd:pfam00912 1 DGTLLAELGE-ENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 138 HDKTWKRKLLEAMYTVRLEVNYNKNHILEGYLNTIYYGHGAYGIEAASRLYFDKTAKELTLAEASMLAGIPKGPSVYSPF 217
Cdd:pfam00912 80 PERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPL 159
|
170
....*....|....*...
gi 1264778634 218 LKEDRAKGRQALILDEMV 235
Cdd:pfam00912 160 RNPERAKRRRNLVLDRMV 177
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
88-579 |
5.14e-71 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 246.99 E-value: 5.14e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 88 LSIEDQRFYKHHGFDMKRIAGAIVADLKAMAKVQGASTITQQYARNLYLDHDKTWKRKLLEAMYTVRLEVNYNKNHILEG 167
Cdd:PRK09506 228 LATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALIMDARYSKDRILEL 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 168 YLNTIYYGHGA----YGIEAASRLYFDKTAKELTLAEASMLAGIPKGPSVYSPFLKEDRAKGRQALILDEMVEQGYITKQ 243
Cdd:PRK09506 308 YLNEVYLGQSGddqiRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNPKLALERRNLVLRLLQQQQIIDQE 387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 244 QAALAKKEPltfasLDTKKVAEV---APYFQDAVQASLLRDVGLDEQALQrgGLRIYTTLDPKLQAVAEQAVKDYIP--- 317
Cdd:PRK09506 388 LYDMLSARP-----LGVQPKGGVispQPAFMQMVRQELQAKLGDKVKDLS--GVKIFTTLDPVSQDAAEKAVEEGIPalk 460
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 318 ---DTTNIQTALVSMNPTTGEVAALVGGTDYNMSQFNRATQAVRQPGSTFKPFLYYAALER--GFTPATRLKSEYTVFTL 392
Cdd:PRK09506 461 kqrKLSDLETAMVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSIGSLAKPATYLTALSQpdKYRLNTWIADAPISLRQ 540
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 393 GDGVSkYKPKNYKDYYADDfVTMAQALAVSDNIYAVKTNLFLGDDALAKTAKQFGI-KSALKDVPSLALGTSPVKPIEMV 471
Cdd:PRK09506 541 PNGQV-WSPQNDDRRFSGR-VMLVDALTRSMNVPTVNLGMALGLPAVTDTWIKLGVpKDQLNPVPAMLLGALNLTPIEVA 618
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 472 NAYSMFANGGKEVKPTFIRRIMDHEGNILYDAHLESKQVLDKSKAFVMEEMMTGMFNKKlssyaavTGQSMLSKLSRTY- 550
Cdd:PRK09506 619 QAFQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLYTMQQVVQRG-------TGRQLGAKYPNLHl 691
|
490 500 510
....*....|....*....|....*....|.
gi 1264778634 551 AGKSGSTET--DSWMIGFTPQIVTGVWVGYD 579
Cdd:PRK09506 692 AGKTGTTNDlvDSWFAGIDGKEVTITWVGRD 722
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
67-625 |
4.26e-67 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 234.74 E-value: 4.26e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 67 EMQKRYNVSLNEISPYVKEATLSIEDQRFYKHHGFDMKRIAGAIVADLKAMAKVQGASTITQQYARNLYLDHDKTWKRKL 146
Cdd:PRK14850 153 EGKKRLFIPRNQYPEMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMSGHTIQGGSTLTQQLVKNLFLTNTRSLWRKI 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 147 LEAMYTVRLEVNYNKNHILEGYLNTIYYGHGA----YGIEAASRLYFDKTAKELTLAEASMLAGIPKGPSVYSPFLKEDR 222
Cdd:PRK14850 233 NEIYMALILDRFYSKDRILELYLNEVYLGQDGneqiRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNPWTNPNL 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 223 AKGRQALILDEMVEQGYITKQQAALAKKEPLTFASLDtkKVAEVAPYFQDAVQASLLRDVGLDEQALQrgGLRIYTTLDP 302
Cdd:PRK14850 313 TLKRRNLVLFLLYKQKVITRKLYKDLCSRPLNVQSKG--NIISSHPAFIQLVCEEFHKKIHYPFKNFS--GTKIFTTLDY 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 303 KLQAVAEQAVKDYIP------DTTNIQTALVSMNPTTGEVAALVGGTDYNMSQFNRATQAVRQPGSTFKPFLYYAALER- 375
Cdd:PRK14850 389 ISQNAAEQAVKIGIPilkrkkRLKDLEVAMVIIDRFSGEVRALIGSSKPEFNGYNRALKARRSIGSLSKPITYLTALSQp 468
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 376 -GFTPATRLkSEYTVFTLGDGVSKYKPKNYkDYYADDFVTMAQALAVSDNIYAVKTNLFLGDDALAKTAKQFGIKS-ALK 453
Cdd:PRK14850 469 eKYHLNTWI-SDTPISIKLDNGQYWTPKNN-NFSFSGKVMLIDALIHSINIPTVHLSINLGLKKLVDSWILLGISSnYIT 546
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 454 DVPSLALGTSPVKPIEMVNAYSMFANGGKEVKPTFIRRIMDHEGNILYDAHLESKQVLDKSKAFVMEEMMTGMFNKKLSS 533
Cdd:PRK14850 547 PLPSISLGAINLTPMEVAQVFQIIGSGGYKSSLSSIRSIISDDNKVLYQNFPQSKHVESSQASYLTLYAMQQVVKSGTAK 626
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 534 YAAVTGQSMlsklsrTYAGKSGSTE--TDSWMIGFTPQIVTGVWVGYDQPKSISNVAEQGyAKKIWTDTMEkgLDGQPKK 611
Cdd:PRK14850 627 SLGTIFKEF------SLAGKTGTTNnlVDSWFVGIDGKQVVITWIGRDNNHTTKLYGSSG-AMKIYKRYLQ--YQNPVPL 697
|
570
....*....|....
gi 1264778634 612 EFKQPSDVVAVNIN 625
Cdd:PRK14850 698 VLKAPNNINMFYIN 711
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
71-596 |
2.03e-52 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 193.76 E-value: 2.03e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 71 RYNVSLNEISPYVKEATLSIEDQRFYKHHGFDMKRIAGAIVADLKAMAKVQGASTITQQYARnlYLD-HDKTWKRKLLEA 149
Cdd:PRK11240 62 RYPVTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARAAWQDLTSGRVISGGSTLTMQVAR--LLDpHPRTFGGKIRQL 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 150 MYTVRLEVNYNKNHILEGYLNTIYYGHGAYGIEAASRLYFDKTAKELTLAEASMLAGIPKGPSVYSPFLKEDRAKGRQAL 229
Cdd:PRK11240 140 WRALQLEWHLSKREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEAARNK 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 230 ILDEMVEQGYITKQQAALAKKEPLTFASldtKKVAEVAPYFQDavqasllRDVGLDEQALqrgglrIYTTLDPKLQAVAE 309
Cdd:PRK11240 220 VLERMAEQGVWSAEQVKESREEPVWLAP---RQMPQLAPLFAR-------MMLGKSKSDK------IVTTLDAGLQRRLE 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 310 QAV---KDYIPDTTNIqtALVSMNPTTGEVAALVGGTDYN-MSQFNRA--TQAVRQPGSTFKPFLYYAALERGFTPATRL 383
Cdd:PRK11240 284 DLAlnwKGRLPPRSSL--AMIVVDHTDMAVRGWVGSVDLNdDSRFGHVdmVNAIRSPGSVLKPFVYGLALDDGLIHPASL 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 384 kseytvftLGDgvskyKPKNYKDYYADDF-------VTMAQALAVSDNIYAVKTNLFLGDDALAKTAKQFGIKSALKDV- 455
Cdd:PRK11240 362 --------LQD-----VPRRTGDYRPGNFdsgfhgpVSMSEALVRSLNLPAVQVLEAYGPKRFAAKLRNVGLPLYLPAGa 428
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 456 -PSLA--LGTSPVKPIEMVNAYSMFANGGKEVKPTF-------------------IRRIMDHEGNILYDAHLESKQVLdk 513
Cdd:PRK11240 429 ePNLSliLGGAGARLEDMVAAYSAFARHGKAAKLRLqpddpllerplmspgaawiIRRIMADEAQPLPDAALPRVVPL-- 506
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 514 skafvmeemmtgmfnkklssyAAVTGQSmlsklsrtYAGKsgstetDSWMIGFTPQIVTGVWVGydQPKSISNVAEQGYA 593
Cdd:PRK11240 507 ---------------------AWKTGTS--------YGYR------DAWAIGVNARYVIGIWTG--RPDGTPVVGQFGFA 549
|
...
gi 1264778634 594 KKI 596
Cdd:PRK11240 550 SAV 552
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
279-583 |
4.88e-42 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 160.76 E-value: 4.88e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 279 LRDVGLDEQALQrgGLRIYTTLDPKLQAVAEQAVKDYIPDTTNIQTALVSMNPTTGEVAALVGGTDYNMSQF-------- 350
Cdd:COG0768 206 IRDLGEEKPPVP--GKDLVLTIDSDLQKIAEEALKKAVEEYKAKSGAVVVMDPKTGEILAMASYPSFDPNLFvggpdepl 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 351 -NRATQAVRQPGSTFKPFLYYAALERG-FTPATRLKSEYTvFTLGDG-VSKYKPKNYKDyyaddfVTMAQALAVSDNIYA 427
Cdd:COG0768 284 rNRAVQGTYEPGSTFKPFTAAAALEEGvITPDTTFDCPGY-YRVGGRtIRDWDRGGHGT------LTLTEALAKSSNVGF 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 428 VKTNLFLGDDALAKTAKQFGI--KSALkDVPSLALGTSP--------------------VKPIEMVNAYSMFANGGKEVK 485
Cdd:COG0768 357 YKLALRLGIDKLYDYLKKFGLgqKTGI-DLPGEASGLLPspkrwypgetatmsigqglsVTPLQLAQAYAAIANGGVLVK 435
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 486 PTFIRRIMDHEGNILYDAHLESKQVLDKSKAFVMEEMMTGMFNKKL--SSYAAVTGQSMlsklsrtyAGKSGSTET---- 559
Cdd:COG0768 436 PHLVKEIVDPDGEVVKEEPEVLRRVISPETAETVREGMEGVVNEPGgtARRAAIPGYRV--------AGKTGTAQVvdig 507
|
330 340 350
....*....|....*....|....*....|....*..
gi 1264778634 560 ---------DSWMIGFTP----QIVTGVWVgyDQPKS 583
Cdd:COG0768 508 nggyykgrhIASFVGFAPadnpRYAVAVVV--ENPGG 542
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
67-234 |
5.50e-42 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 151.85 E-value: 5.50e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 67 EMQKRYnVSLNEISPYVKEATLSIEDQRFYKHHGFDMKRIAGAIVADLKAMAKVQGASTITQQYARNLYLDHDKTWKRKL 146
Cdd:TIGR02070 52 GIQHRW-RPYDQISPNLKRAVIASEDAKFVEHHGFDWEAIQDALEKNEKSGKVVRGGSTISQQLAKNLFLWSGRSYLRKG 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 147 LEAMYTVRLEVNYNKNHILEGYLNTIYYGHGAYGIEAASRLYFDKTAKELTLAEASMLAGIPKGPSVYSPFLKEDRAKGR 226
Cdd:TIGR02070 131 LEAWATWMLETWWSKQRILEVYLNSVEWGNGVFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYYDENRPGPYVRRK 210
|
....*...
gi 1264778634 227 QALILDEM 234
Cdd:TIGR02070 211 ATWILKQM 218
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
69-244 |
2.79e-38 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 141.86 E-value: 2.79e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 69 QKRYNVSLNEISPYVKEATLSIEDQRFYKHHGFDMKRIAGAIVADLKAmAKVQGASTITQQYARNLYLDHDKTWKRKLLE 148
Cdd:PRK13481 43 NKSSFVSADNMPEYVKGAFISMEDERFYKHHGFDLKGTTRALFSTISD-RDVQGGSTITQQVVKNYFYDNERSFTRKVKE 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 149 AMYTVRLEVNYNKNHILEGYLNTIYYGHGAYGIEAASRLYFDKTA-------KELTLAEASMLAGIPKGPSVYSPFLKED 221
Cdd:PRK13481 122 LFVAHRVEKQYSKNEILSFYLNNIYFGDNQYTLEGAANHYFGTTVnknsttmSHITVLQSAILASKVNAPSVYNINDMSE 201
|
170 180
....*....|....*....|...
gi 1264778634 222 RAKGRQALILDEMVEQGYITKQQ 244
Cdd:PRK13481 202 NFTQRVSTNLEKMKQQNYINETQ 224
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
325-602 |
3.35e-33 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 129.46 E-value: 3.35e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 325 ALVSMNPTTGEVAALVGGTDYNMSQF-----NRATQAVRQPGSTFKPFLYYAALERGFTpatrlkSEYTVFTLGDGVsKY 399
Cdd:pfam00905 2 SAVVLDPKTGEVLAMVGKPSYDPNGFigplrNRAVTSRYEPGSTFKPFTALAALDNGVL------KPDETIFDWPGK-QQ 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 400 KPKNYKDYYADDF--VTMAQALAVSDNIYAVKTNLFLGDDALAKTAKQFGI------------------KSALKDVPSLA 459
Cdd:pfam00905 75 GGKSIGDWNQDQVgiGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYgnktgiglpgenagyltpYWLEGATASFG 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 460 LGTSpVKPIEMVNAYSMFANGGKEVKPTFIRRIMDHEgnilyDAHLESKQVLDKSKAFVMEEMMTGMFNKKlssyaavTG 539
Cdd:pfam00905 155 IGLT-ITPLQQAQAYAAIANGGKLVPPHLVKSIEDKV-----DPKVLNKLPISKSTAEKVKDMLRLVVNDG-------TG 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 540 QSMLSKLSRTYAGKSGSTET-------------DSWMIGFT----PQIVtgVWVGYDQPKsisNVAEQGYAKKIWTDTME 602
Cdd:pfam00905 222 TGTAAVPGYKVAGKTGTAQVagpkgggyydgaqIGWFVGYApadnPKYA--FAVLIDDPK---RYYGGKVAAPIFKDILE 296
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
293-591 |
5.85e-30 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 125.33 E-value: 5.85e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 293 GLRIYTTLDPKLQAVAEQAVKDYIpdttniqTALVSMNPTTGEVAALVGGTDYNMSQF---------------------N 351
Cdd:TIGR03423 225 GKDLVLTIDARLQQAAEKALGGRR-------GAVVVMDPRTGEILAMVSTPSFDPNLFvdgisskdykallndpdrpllN 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 352 RATQAVRQPGSTFKPFLYYAALERG-FTPatrlksEYTVFTLGdgvsKYKPKNYKdyYADD------FVTMAQALAVSDN 424
Cdd:TIGR03423 298 RAIQGVYPPGSTFKPVVALAALEEGvITP------ETRIYCPG----YFQLGGRR--FRCWkrgghgRVDLRKAIEESCD 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 425 IYAVKTNLFLGDDALAKTAKQFGIKSALK-DVPSLALGTSP-----------------------------VKPIEMVNAY 474
Cdd:TIGR03423 366 VYFYQLALRLGIDKIAEYAKRFGFGQKTGiDLPGEKSGLVPsrewkrkrfgqpwypgdtlnvsigqgyvlVTPLQLAVAT 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 475 SMFANGGKEVKPTFIRRIMDHEGNILYDAHLESKQVLDKSKAF--VMEEMMTGMFNKKLSsyaavTGQSMLSKLSRTYAG 552
Cdd:TIGR03423 446 AALANGGKLYKPHLVKSIEDPDGGVVRRTEPEVLRPLPISPENldVVREGMRDVVNGPGG-----TARRARLGLPYKMAG 520
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 553 KSGSTET-------------------D-SWMIGFTPqivtgvwvgYDQPK-SISNVAEQG 591
Cdd:TIGR03423 521 KTGTAQVvslkqgekydaeqiperlrDhALFVAFAP---------YDNPKiAVAVIVEHG 571
|
|
| PRK10795 |
PRK10795 |
penicillin-binding protein 2; Provisional |
284-383 |
1.07e-06 |
|
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain] Cd Length: 634 Bit Score: 52.08 E-value: 1.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 284 LDEQALQrGGLRIYTTLDPKLQAVAEQAVkdyipdtTNIQTALVSMNPTTGEVAALVGGTDYNMSQF------------- 350
Cdd:PRK10795 240 LHEQPPQ-AGHDIYLTLDLKLQQYIETLL-------AGSRAAVVVTDPRTGGILALVSTPSYDPNLFvdgisskdysgll 311
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1264778634 351 --------NRATQAVRQPGSTFKPFLYYAALERG-FTPATRL 383
Cdd:PRK10795 312 ndpnrpliNRATQGVYPPASTVKPYVAVSALSAGvITRNTSL 353
|
|
| PRK15105 |
PRK15105 |
peptidoglycan synthase FtsI; Provisional |
299-451 |
3.34e-04 |
|
peptidoglycan synthase FtsI; Provisional
Pssm-ID: 185060 [Multi-domain] Cd Length: 578 Bit Score: 43.66 E-value: 3.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 299 TLDPKLQAVAEQAVKDYIP-DTTNIQTA-LVSMNptTGEVAALVGGTDYNMSQF---------NRATQAVRQPGSTFKPF 367
Cdd:PRK15105 234 SIDERLQALVYRELNNAVAfNKAESGSAvLVDVN--TGEVLAMANSPSYNPNNLsgtpkdamrNRAITDVFEPGSTVKPM 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264778634 368 LYYAALERGFTpatrlkSEYTVF-TLGDGVSKYKPKNYKDYYAddfVTMAQALAVSDNIYAVKTNLFLGDDALAKTAKQF 446
Cdd:PRK15105 312 VVMTALQRGVV------KENSVLnTVPYRINGHEIKDVARYSE---LTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRF 382
|
....*
gi 1264778634 447 GIKSA 451
Cdd:PRK15105 383 GLGKA 387
|
|
| |
