|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1314-1694 |
2.39e-21 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 102.91 E-value: 2.39e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1314 EHILTPDSSFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEvvEPKDTAIYQKDEA 1393
Cdd:PTZ00121 1299 EEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAE--EKAEAAEKKKEEA 1376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1394 lhvKNEAVKQQDKALEQKGRDlEQKDTALEQKDKALEPKDKDlEEKDKALEQKDKiPEEKDKALEQKDTAlEQKDKALEP 1473
Cdd:PTZ00121 1377 ---KKKADAAKKKAEEKKKAD-EAKKKAEEDKKKADELKKAA-AAKKKADEAKKK-AEEKKKADEAKKKA-EEAKKADEA 1449
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1474 KDKDLEQKDRvlEQKEKIPEEKDKALDQKVRSVEHKAPEDT--VAEMKDRDLEQTDKAPEQKHQAQEQKDkvSEKKDQAL 1551
Cdd:PTZ00121 1450 KKKAEEAKKA--EEAKKKAEEAKKADEAKKKAEEAKKADEAkkKAEEAKKKADEAKKAAEAKKKADEAKK--AEEAKKAD 1525
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1552 EQKYWALGQKDEALEQ--------NIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKleaLLEKTKALGL 1623
Cdd:PTZ00121 1526 EAKKAEEAKKADEAKKaeekkkadELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEA---RIEEVMKLYE 1602
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 313104325 1624 EESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQD 1694
Cdd:PTZ00121 1603 EEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1352-1681 |
1.00e-19 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 97.90 E-value: 1.00e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1352 RTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEP 1431
Cdd:PTZ00121 1290 KKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAA 1369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1432 KDKDLEEKDKALEQKDKiPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRvlEQKEKIPEEKDKALDQKvrsveHKAP 1511
Cdd:PTZ00121 1370 EKKKEEAKKKADAAKKK-AEEKKKADEAKKKAEEDKKKADELKKAAAAKKKA--DEAKKKAEEKKKADEAK-----KKAE 1441
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1512 EDTVAEMKDRDLEQTDKAPEQKHQAQEQK-----DKVSEKKDQALEQKYWALGQKDEAlEQNIQALEENHQTQEQESLVQ 1586
Cdd:PTZ00121 1442 EAKKADEAKKKAEEAKKAEEAKKKAEEAKkadeaKKKAEEAKKADEAKKKAEEAKKKA-DEAKKAAEAKKKADEAKKAEE 1520
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1587 EDKTRKPKMLEE--KSPEKVKAMEEKLEALLEKTKAL-GLEESLVQEGRAREQEEKYW--------------RGQDVVQE 1649
Cdd:PTZ00121 1521 AKKADEAKKAEEakKADEAKKAEEKKKADELKKAEELkKAEEKKKAEEAKKAEEDKNMalrkaeeakkaeeaRIEEVMKL 1600
|
330 340 350
....*....|....*....|....*....|..
gi 313104325 1650 WQETSPTREEPAGEQKELAPAWEDTSPEQDNR 1681
Cdd:PTZ00121 1601 YEEEKKMKAEEAKKAEEAKIKAEELKKAEEEK 1632
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1350-1666 |
3.34e-19 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 95.98 E-value: 3.34e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1350 KDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAI-YQKDEALHVKNEAVKQQD---KALEQKGRDLEQKDTALEQK 1425
Cdd:PTZ00121 1417 KKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEeAKKAEEAKKKAEEAKKADeakKKAEEAKKADEAKKKAEEAK 1496
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1426 DKALEPKDKDlEEKDKALEQKD----------KIPEEKDKALEQKDTalEQKDKALE-PKDKDLEQKDRVLEQKEKIPEE 1494
Cdd:PTZ00121 1497 KKADEAKKAA-EAKKKADEAKKaeeakkadeaKKAEEAKKADEAKKA--EEKKKADElKKAEELKKAEEKKKAEEAKKAE 1573
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1495 KDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEA-----LEQNI 1569
Cdd:PTZ00121 1574 EDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAeekkkAEELK 1653
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1570 QALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQ-----EEKYWRGQ 1644
Cdd:PTZ00121 1654 KAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEElkkaeEENKIKAE 1733
|
330 340
....*....|....*....|..
gi 313104325 1645 DVVQEWQETSPTREEPAGEQKE 1666
Cdd:PTZ00121 1734 EAKKEAEEDKKKAEEAKKDEEE 1755
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1334-1668 |
3.51e-19 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 95.98 E-value: 3.51e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1334 ALEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVlQQKDKTLEHKEVVEPKdtaiyQKDEALHVKNEAVKQQDKALEQKGR 1413
Cdd:PTZ00121 1266 ARRQAAIKAEEARKADELKKAEEKKKADEAKKA-EEKKKADEAKKKAEEA-----KKADEAKKKAEEAKKKADAAKKKAE 1339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1414 DLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKipEEKDKALEQKDTAlEQKDKALEPKDKDLEQKDRVLEQKEKiPE 1493
Cdd:PTZ00121 1340 EAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKE--EAKKKADAAKKKA-EEKKKADEAKKKAEEDKKKADELKKA-AA 1415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1494 EKDKALDQKvrsveHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKdKVSEKKDQALEQKywalgQKDEALEQniqaLE 1573
Cdd:PTZ00121 1416 AKKKADEAK-----KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAK-KAEEAKKKAEEAK-----KADEAKKK----AE 1480
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1574 ENHQTQEQESLVQEDKtRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKywRGQDVVQEWQET 1653
Cdd:PTZ00121 1481 EAKKADEAKKKAEEAK-KKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEK--KKADELKKAEEL 1557
|
330
....*....|....*
gi 313104325 1654 SPTREEPAGEQKELA 1668
Cdd:PTZ00121 1558 KKAEEKKKAEEAKKA 1572
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1345-1744 |
3.99e-19 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 95.59 E-value: 3.99e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1345 KVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVK--NEAVK--QQDKALEQKGRDLEQKDT 1420
Cdd:PTZ00121 1379 KADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKkaDEAKKkaEEAKKADEAKKKAEEAKK 1458
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1421 ALEQKDKALEPKD-----KDLEEKDKALEQKDKIPEEKDKALEQKDTAlEQKDKALEPKDKDLEQKDRVLEQKE--KIPE 1493
Cdd:PTZ00121 1459 AEEAKKKAEEAKKadeakKKAEEAKKADEAKKKAEEAKKKADEAKKAA-EAKKKADEAKKAEEAKKADEAKKAEeaKKAD 1537
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1494 EKDKALDQKVRSVEHKAPEDTVAEMKdRDLEQTDKAPEQKHQA--------QEQKDKVSEKKDQALEQKYWALGQKDEAL 1565
Cdd:PTZ00121 1538 EAKKAEEKKKADELKKAEELKKAEEK-KKAEEAKKAEEDKNMAlrkaeeakKAEEARIEEVMKLYEEEKKMKAEEAKKAE 1616
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1566 EQNIQA-----LEENHQTQEQESLVQEDKTRKPKML-EEKSPEKVKAMEEKLEALLEKTKAlglEESLVQEGRAREQEEK 1639
Cdd:PTZ00121 1617 EAKIKAeelkkAEEEKKKVEQLKKKEAEEKKKAEELkKAEEENKIKAAEEAKKAEEDKKKA---EEAKKAEEDEKKAAEA 1693
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1640 YWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWRElscERKVWFPHELDGQGARP 1719
Cdd:PTZ00121 1694 LKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDE---EEKKKIAHLKKEEEKKA 1770
|
410 420
....*....|....*....|....*
gi 313104325 1720 HYTEERESTFLDEGPDDEQEVPLRE 1744
Cdd:PTZ00121 1771 EEIRKEKEAVIEEELDEEDEKRRME 1795
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1343-1668 |
1.81e-17 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 90.20 E-value: 1.81e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1343 EDKVPGLKDRTSEQKKEPEPKDevlQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQD--KALEQK----GRDLE 1416
Cdd:PTZ00121 1223 AKKAEAVKKAEEAKKDAEEAKK---AEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADElkKAEEKKkadeAKKAE 1299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1417 QKDTALEQKDKALEPKDKDlEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKD 1496
Cdd:PTZ00121 1300 EKKKADEAKKKAEEAKKAD-EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKK 1378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1497 KALDQKVRSVEHKAPEDTV--AEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKdQALEQKYWAlGQKDEALEQNIQAlEE 1574
Cdd:PTZ00121 1379 KADAAKKKAEEKKKADEAKkkAEEDKKKADELKKAAAAKKKADEAKKKAEEKK-KADEAKKKA-EEAKKADEAKKKA-EE 1455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1575 NHQTQEQESLVQEdkTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGL---EESLVQEGRAREQEEKywRGQDVVQEWQ 1651
Cdd:PTZ00121 1456 AKKAEEAKKKAEE--AKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAkkaAEAKKKADEAKKAEEA--KKADEAKKAE 1531
|
330
....*....|....*..
gi 313104325 1652 ETSPTREEPAGEQKELA 1668
Cdd:PTZ00121 1532 EAKKADEAKKAEEKKKA 1548
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1352-1681 |
1.06e-14 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 81.34 E-value: 1.06e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1352 RTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVK-QQDKALEQKGRDLEQKDTALEQKDKALE 1430
Cdd:PTZ00121 1558 KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKaEEAKKAEEAKIKAEELKKAEEEKKKVEQ 1637
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1431 PKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKdKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKA 1510
Cdd:PTZ00121 1638 LKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAK-KAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKK 1716
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1511 PEDtvaEMKDRDLEQTDKAPEQKHQAQEQKDKVSE-KKDQALEQKYWALGQKDEALEQNIQaleenhqtQEQESLVQEDK 1589
Cdd:PTZ00121 1717 KAE---ELKKAEEENKIKAEEAKKEAEEDKKKAEEaKKDEEEKKKIAHLKKEEEKKAEEIR--------KEKEAVIEEEL 1785
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1590 TRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAP 1669
Cdd:PTZ00121 1786 DEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGN 1865
|
330
....*....|..
gi 313104325 1670 AWEDTSPEQDNR 1681
Cdd:PTZ00121 1866 KEADFNKEKDLK 1877
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1349-1630 |
9.16e-13 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 74.29 E-value: 9.16e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1349 LKDRTSEQKKEPEPKDEVLQ--QKDKTLEHKEVVEPKDTAIYQKDEAlhvkneavkqqdkaleqkgRDLEQKDTALEQKD 1426
Cdd:TIGR04523 396 LESKIQNQEKLNQQKDEQIKklQQEKELLEKEIERLKETIIKNNSEI-------------------KDLTNQDSVKELII 456
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1427 KALEPKDKDLEEKDKALEqkDKIPEEKDKaLEQKDTALEQKDK---ALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKV 1503
Cdd:TIGR04523 457 KNLDNTRESLETQLKVLS--RSINKIKQN-LEQKQKELKSKEKelkKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEK 533
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1504 RSVEHKAPEdtvaemKDRDLEqTDKAPEQKHQAQEQKDKVSEKKDQaLEQKYWALGQKDEALEQNIQALEENHQTQEQEs 1583
Cdd:TIGR04523 534 KEKESKISD------LEDELN-KDDFELKKENLEKEIDEKNKEIEE-LKQTQKSLKKKQEEKQELIDQKEKEKKDLIKE- 604
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 313104325 1584 lvQEDKTRKPKMLEEKSpEKVKAMEEKLEalLEKTKALGLEESLVQE 1630
Cdd:TIGR04523 605 --IEEKEKKISSLEKEL-EKAKKENEKLS--SIIKNIKSKKNKLKQE 646
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1335-1554 |
1.05e-12 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 74.41 E-value: 1.05e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1335 LEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKalEQKGRD 1414
Cdd:PTZ00121 1586 AKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEE--ENKIKA 1663
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1415 LEQKDTALEQKDKALEPKdKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEE 1494
Cdd:PTZ00121 1664 AEEAKKAEEDKKKAEEAK-KAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED 1742
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 313104325 1495 KDKALDQKVRSVEHKapedTVAEMKDRDLEQTDKAPEQKHQA-QEQKDKVSEKKDQALEQK 1554
Cdd:PTZ00121 1743 KKKAEEAKKDEEEKK----KIAHLKKEEEKKAEEIRKEKEAViEEELDEEDEKRRMEVDKK 1799
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
2041-2667 |
3.43e-12 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 73.05 E-value: 3.43e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2041 PTVPPRP-EPGPSMEPSLTP-PAVPPR-----------APILSKGPSPPLNGNILSCSPDRRSPSPKESGRShwddstsd 2107
Cdd:PHA03247 2506 PDAPPAPsRLAPAILPDEPVgEPVHPRmltwirgleelASDDAGDPPPPLPPAAPPAAPDRSVPPPRPAPRP-------- 2577
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2108 SELEKGARE-QPEKEAQSPSPPHPI-PMGSPtlwPETEAHVSPPLDSHlgPARPSLDFPASAfGFSSLQPAPPQLPSPAE 2185
Cdd:PHA03247 2578 SEPAVTSRArRPDAPPQSARPRAPVdDRGDP---RGPAPPSPLPPDTH--APDPPPPSPSPA-ANEPDPHPPPTVPPPER 2651
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2186 PRSAPCGSLAFSGDRALALA----PGPPTRTRHDEYLEVTKAPSLDSSLP--QLPSPSSPGAPLLSNLPRPASPALSEGS 2259
Cdd:PHA03247 2652 PRDDPAPGRVSRPRRARRLGraaqASSPPQRPRRRAARPTVGSLTSLADPppPPPTPEPAPHALVSATPLPPGPAAARQA 2731
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2260 SSEATTPVISSvaerfsPSLEAAEQESGELDPGMEPAAHslwdlTPLSPAPPAslDLALAPAPSLPgdmgdgiLPCHLEC 2339
Cdd:PHA03247 2732 SPALPAAPAPP------AVPAGPATPGGPARPARPPTTA-----GPPAPAPPA--APAAGPPRRLT-------RPAVASL 2791
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2340 SEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAeneeaaacpawergawPEGAERSSRPDTLLSPEQPVCPAGGS 2419
Cdd:PHA03247 2792 SESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLP----------------PPTSAQPTAPPPPPGPPPPSLPLGGS 2855
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2420 GGP--PSSASPEVEAGPQGCATEPRPHRGELSpsflNPPLPPSIDDRDLSteevrlvgrggrrrvggpgttggpcPVTDE 2497
Cdd:PHA03247 2856 VAPggDVRRRPPSRSPAAKPAAPARPPVRRLA----RPAVSRSTESFALP-------------------------PDQPE 2906
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2498 TPPTSASDSGSSQSDSDVPPETEECPsitaeaaldsdedgdflpvdkaggvsgthhprpghdppplpqPDPRPSPPRPDV 2577
Cdd:PHA03247 2907 RPPQPQAPPPPQPQPQPPPPPQPQPP------------------------------------------PPPPPRPQPPLA 2944
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2578 CMADPEGLSSESGRVERLREKEKVQGRVgrrapgkakpASPARRLDLRGKRSPTPGKGPADRASRAPPRPRSTTSQVTPA 2657
Cdd:PHA03247 2945 PTTDPAGAGEPSGAVPQPWLGALVPGRV----------AVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLALH 3014
|
650
....*....|
gi 313104325 2658 EEKDgHSPMS 2667
Cdd:PHA03247 3015 EETD-PPPVS 3023
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1334-1667 |
6.95e-12 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 71.63 E-value: 6.95e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1334 ALEDIAIKWEDkvpgLKDRTSEQKKEPEPKDEVLQQKDKTLE---------HKEVVEPKDTAiyQKDEALHVKNEAVKQQ 1404
Cdd:PRK03918 180 RLEKFIKRTEN----IEELIKEKEKELEEVLREINEISSELPelreeleklEKEVKELEELK--EEIEELEKELESLEGS 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1405 DKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKD------TALEQKDKALEPKDKDL 1478
Cdd:PRK03918 254 KRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELReiekrlSRLEEEINGIEERIKEL 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1479 EQKDRVLEQ-KEKIPEEKDK--ALDQKVRSVEH-KAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQK 1554
Cdd:PRK03918 334 EEKEERLEElKKKLKELEKRleELEERHELYEEaKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITAR 413
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1555 YWALGQKDEALEQNIQALEENHQ---------TQEQESLVQEDKTRKPKMLEEKSPE------KVKAMEEKLEALLEKTK 1619
Cdd:PRK03918 414 IGELKKEIKELKKAIEELKKAKGkcpvcgrelTEEHRKELLEEYTAELKRIEKELKEieekerKLRKELRELEKVLKKES 493
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 313104325 1620 ALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKEL 1667
Cdd:PRK03918 494 ELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEI 541
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1357-1693 |
2.97e-11 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 69.62 E-value: 2.97e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1357 KKEPEPKDEVLQQK------DKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKA-----LEQKGRDLEQKDTALEQK 1425
Cdd:pfam02463 172 KEALKKLIEETENLaeliidLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYldylkLNEERIDLLQELLRDEQE 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1426 DKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKvrs 1505
Cdd:pfam02463 252 EIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEK--- 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1506 vehkapedtvaemkdrdleQTDKAPEQKHQAQEQKDKVSEKKDQALEQK--YWALGQKDEALEQNIQALEENHQTQEQES 1583
Cdd:pfam02463 329 -------------------ELKKEKEEIEELEKELKELEIKREAEEEEEeeLEKLQEKLEQLEEELLAKKKLESERLSSA 389
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1584 LVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDvvqEWQETSPTREEPAGE 1663
Cdd:pfam02463 390 AKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKE---ELEKQELKLLKDELE 466
|
330 340 350
....*....|....*....|....*....|
gi 313104325 1664 QKELAPAWEDTSPEQDNRYWRGREDVALEQ 1693
Cdd:pfam02463 467 LKKSEDLLKETQLVKLQEQLELLLSRQKLE 496
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1349-1621 |
3.92e-11 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 68.89 E-value: 3.92e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1349 LKDRTSEQKKEPEPKDEVLQQKDKTLEHKEvvepkdtaiyQKDEALHVKNEAVKQQDKaleqkgrDLEQKDTALEQKDKA 1428
Cdd:TIGR04523 340 LNEQISQLKKELTNSESENSEKQRELEEKQ----------NEIEKLKKENQSYKQEIK-------NLESQINDLESKIQN 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1429 LEPKDKDLEEKDKALEQ-KDKIPEEKD-------------KALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIP-- 1492
Cdd:TIGR04523 403 QEKLNQQKDEQIKKLQQeKELLEKEIErlketiiknnseiKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIkq 482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1493 --EEKDKALDQKVRSV-----EHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYwalGQKDEAL 1565
Cdd:TIGR04523 483 nlEQKQKELKSKEKELkklneEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDF---ELKKENL 559
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1566 EQNI----QALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKAL 1621
Cdd:TIGR04523 560 EKEIdeknKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKEL 619
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1386-1692 |
5.69e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 68.42 E-value: 5.69e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1386 AIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKAL---------EQKDKIPEEKDK- 1455
Cdd:COG1196 233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEyellaelarLEQDIARLEERRr 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1456 -ALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIpEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKH 1534
Cdd:COG1196 313 eLEERLEELEEELAELEEELEELEEELEELEEELEEA-EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1535 QAQEQKDKVSEKKDQALEQkywALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRkpKMLEEKSPEKVKAMEEKLEAL 1614
Cdd:COG1196 392 LRAAAELAAQLEELEEAEE---ALLERLERLEEELEELEEALAELEEEEEEEEEALE--EAAEEEAELEEEEEALLELLA 466
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 313104325 1615 LEKTKALGLEESLVQEGRAREQEE-KYWRGQDVVQEWQEtsptREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALE 1692
Cdd:COG1196 467 ELLEEAALLEAALAELLEELAEAAaRLLLLLEAEADYEG----FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE 541
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1981-2564 |
6.05e-11 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 68.81 E-value: 6.05e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1981 PACPTREPPLGAAGDWPPclstkEAAAGRNTSAEKELSSPISPKSLqsdTPTFSYAALAGPTVPPR-------------- 2046
Cdd:PHA03247 2475 PGAPVYRRPAEARFPFAA-----GAAPDPGGGGPPDPDAPPAPSRL---APAILPDEPVGEPVHPRmltwirgleelasd 2546
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2047 --PEPGPSMEPSLTPPAVPPRAPILSKGPSPPlngNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQS 2124
Cdd:PHA03247 2547 daGDPPPPLPPAAPPAAPDRSVPPPRPAPRPS---EPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHA 2623
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2125 PSPPHPIPMGSPTLWPETEAHVSPPL---DSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPRsAPCGSLAFSGDRA 2201
Cdd:PHA03247 2624 PDPPPPSPSPAANEPDPHPPPTVPPPerpRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAAR-PTVGSLTSLADPP 2702
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2202 lalAPGPPTRTRHDEYLEVTKAPSLDSSLPQlPSPSSPGAPLLSnlPRPASPALSEGSSSEATTPVISSVAERFSPSLEA 2281
Cdd:PHA03247 2703 ---PPPPTPEPAPHALVSATPLPPGPAAARQ-ASPALPAAPAPP--AVPAGPATPGGPARPARPPTTAGPPAPAPPAAPA 2776
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2282 AEQESGELDPGMEPAAHSLWDLtPLSPAPPASLDLALAPAPSLPGDMG-DGILPCHLECSEAATEKPSPFQVPSE----- 2355
Cdd:PHA03247 2777 AGPPRRLTRPAVASLSESRESL-PSPWDPADPPAAVLAPAAALPPAASpAGPLPPPTSAQPTAPPPPPGPPPPSLplggs 2855
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2356 -----DCAANGPTETSPNPPG------------PAPAKAENEEAAACPAWERGAWPEGAERSSRPDTLLSPEQPVCPAGG 2418
Cdd:PHA03247 2856 vapggDVRRRPPSRSPAAKPAaparppvrrlarPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP 2935
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2419 SGGPPSSASPEVEAGPQGCAT--EPRPHRGELSPSFLNPP---LPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCP 2493
Cdd:PHA03247 2936 PPRPQPPLAPTTDPAGAGEPSgaVPQPWLGALVPGRVAVPrfrVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLALHE 3015
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 313104325 2494 VTDETPPTSASDSGssqsdsdVPPETEECpsiTAEAALDSD-EDGDFLPVDkaggvsgthhPRPGhdppplP 2564
Cdd:PHA03247 3016 ETDPPPVSLKQTLW-------PPDDTEDS---DADSLFDSDsERSDLEALD----------PLPP------E 3061
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1357-1726 |
1.85e-10 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 66.92 E-value: 1.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1357 KKEPEPKDEVLQQkdktLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQkgrDLEQKDTALEQKDKALEPKDKDL 1436
Cdd:TIGR00618 159 KAKSKEKKELLMN----LFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTL---CTPCMPDTYHERKQVLEKELKHL 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1437 EEKDKALEQKDKIPEEKDKALEQKDtaleQKDKALepkdKDLEQKDRVLEQKEKIPEEKDKALDQKvrsvEHKAPedtVA 1516
Cdd:TIGR00618 232 REALQQTQQSHAYLTQKREAQEEQL----KKQQLL----KQLRARIEELRAQEAVLEETQERINRA----RKAAP---LA 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1517 EMKDRdLEQTDKAPEQKHQA-QEQKDKVSE--KKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKP 1593
Cdd:TIGR00618 297 AHIKA-VTQIEQQAQRIHTElQSKMRSRAKllMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQH 375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1594 KMLeekspEKVKAMEEKLEALLEKTKALGLEESLVQEGRA----REQEEKYWRGQDVVQEWQETSptrEEPAGEQKELAP 1669
Cdd:TIGR00618 376 TLT-----QHIHTLQQQKTTLTQKLQSLCKELDILQREQAtidtRTSAFRDLQGQLAHAKKQQEL---QQRYAELCAAAI 447
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 313104325 1670 AWEDTS-----PEQDNRYWRGREDVALEQDTYWRELSCERKvwfpHELDGQGARPHYTEERE 1726
Cdd:TIGR00618 448 TCTAQCeklekIHLQESAQSLKEREQQLQTKEQIHLQETRK----KAVVLARLLELQEEPCP 505
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1349-1626 |
3.63e-10 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 65.81 E-value: 3.63e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1349 LKDRTSE-QKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQ-KDEALHVKNEavkqqdkaLEQKGRDLEQKDTALEQKD 1426
Cdd:TIGR04523 216 LESQISElKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQlKDEQNKIKKQ--------LSEKQKELEQNNKKIKELE 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1427 KALEPKDKDLEEKDKALEQ------KDKIpEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALD 1500
Cdd:TIGR04523 288 KQLNQLKSEISDLNNQKEQdwnkelKSEL-KNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELE 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1501 QKVRSVE-------HKAPEDTVAEMKDRDLEQTDKAPEQK--------HQAQEQKDKVS--------------------E 1545
Cdd:TIGR04523 367 EKQNEIEklkkenqSYKQEIKNLESQINDLESKIQNQEKLnqqkdeqiKKLQQEKELLEkeierlketiiknnseikdlT 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1546 KKDQALEQKYWALGQKDEALEQNIQALEE--NHQTQEQESLVQE--DKTRKPKML-EEKS--PEKVKAMEEKLEALLEKT 1618
Cdd:TIGR04523 447 NQDSVKELIIKNLDNTRESLETQLKVLSRsiNKIKQNLEQKQKElkSKEKELKKLnEEKKelEEKVKDLTKKISSLKEKI 526
|
....*...
gi 313104325 1619 KALGLEES 1626
Cdd:TIGR04523 527 EKLESEKK 534
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1798-2372 |
5.36e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 65.73 E-value: 5.36e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1798 PPASPPEMVGQRVPsaPGQESPIP-DPKL--------MPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSPAPGPPtpap 1868
Cdd:PHA03247 2556 PPAAPPAAPDRSVP--PPRPAPRPsEPAVtsrarrpdAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPP---- 2629
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1869 eSHTPAPFSWGTAEydsvvAAVQEGAAELEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEPeq 1948
Cdd:PHA03247 2630 -SPSPAANEPDPHP-----PPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADP-- 2701
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1949 tEPEQREPTPYPdersfqyadiyeqmmlTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAekelsSPISPKSLQS 2028
Cdd:PHA03247 2702 -PPPPPTPEPAP----------------HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA-----TPGGPARPAR 2759
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2029 DTPTFSYAALAGPTVPPRPEPgpsmePSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPKESGRShwddstsds 2108
Cdd:PHA03247 2760 PPTTAGPPAPAPPAAPAAGPP-----RRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPA--------- 2825
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2109 elekgAREQPEKEAQSPSPPHPIPMGSPTLwpETEAHVSPPLD-SHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPR 2187
Cdd:PHA03247 2826 -----GPLPPPTSAQPTAPPPPPGPPPPSL--PLGGSVAPGGDvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESF 2898
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2188 SAPCGSlafsgdraLALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLL----SNLPRPASPALSEGSSSEA 2263
Cdd:PHA03247 2899 ALPPDQ--------PERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTdpagAGEPSGAVPQPWLGALVPG 2970
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2264 TTPVISSVAERFSPSLEAAEQES----GELDPGMEPAAHSLwDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLEC 2339
Cdd:PHA03247 2971 RVAVPRFRVPQPAPSREAPASSTppltGHSLSRVSSWASSL-ALHEETDPPPVSLKQTLWPPDDTEDSDADSLFDSDSER 3049
|
570 580 590
....*....|....*....|....*....|...
gi 313104325 2340 SEAATEKPSPFQvpsedcaANGPTETSPNPPGP 2372
Cdd:PHA03247 3050 SDLEALDPLPPE-------PHDPFAHEPDPATP 3075
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
1320-1646 |
1.13e-09 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 64.01 E-value: 1.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1320 DSSFSKSPESLPGPALEDIaikwEDKVPGLKDRTSEQKKEPEPKDEVlQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNE 1399
Cdd:pfam09731 69 PSVVSAVTGESKEPKEEKK----QVKIPRQSGVSSEVAEEEKEATKD-AAEAKAQLPKSEQEKEKALEEVLKEAISKAES 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1400 AVKQqdkALEQKGRDLEQKDTALEQKDKALEP-KDKDLEEKDKALEQKDKIPEEKDKALE-----QKDTALEQKDKALEP 1473
Cdd:pfam09731 144 ATAV---AKEAKDDAIQAVKAHTDSLKEASDTaEISREKATDSALQKAEALAEKLKEVINlakqsEEEAAPPLLDAAPET 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1474 KDKDLEQKDRVLEQKEKIPEEKdkALDQKVRSVEHKAPEDTVAEMK------------DRDLEQTD------KAPEQKHQ 1535
Cdd:pfam09731 221 PPKLPEHLDNVEEKVEKAQSLA--KLVDQYKELVASERIVFQQELVsifpdiipvlkeDNLLSNDDlnsliaHAHREIDQ 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1536 A----QEQKDKVSEKKDQALEQKYWALGQKDEALEQNIqaleENHQTQEQESLVQEdktrkpkmLEEKSPEKVKAMEEKL 1611
Cdd:pfam09731 299 LskklAELKKREEKHIERALEKQKEELDKLAEELSARL----EEVRAADEAQLRLE--------FEREREEIRESYEEKL 366
|
330 340 350
....*....|....*....|....*....|....*
gi 313104325 1612 EALLEKTKALgLEESLVQEGRAREQEEKYWRGQDV 1646
Cdd:pfam09731 367 RTELERQAEA-HEEHLKDVLVEQEIELQREFLQDI 400
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
309-762 |
1.67e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 64.01 E-value: 1.67e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 309 KPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEArselAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEAL 388
Cdd:PTZ00121 1316 KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAA----ADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKK 1391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 389 KAE--KRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPE-LKKISKP--- 462
Cdd:PTZ00121 1392 KADeaKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEeAKKKAEEakk 1471
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 463 --DLKPFTPEVRKT--LYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHR--ELVLSSPE----DLT 532
Cdd:PTZ00121 1472 adEAKKKAEEAKKAdeAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKkaDEAKKAEEkkkaDEL 1551
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 533 QDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGppSTAIQGTPPSVPGLGQEEHVMKEKEL---------VPEVPEEQ 603
Cdd:PTZ00121 1552 KKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEA--KKAEEARIEEVMKLYEEEKKMKAEEAkkaeeakikAEELKKAE 1629
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 604 GSKDRGLDSGAETEEEKDTWEE-KKQREAERLPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQ 682
Cdd:PTZ00121 1630 EEKKKVEQLKKKEAEEKKKAEElKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKK 1709
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 683 KHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLSSLTTPAGATEHVSYIQDETIPGYSET---EQTISDEEIHDEP 759
Cdd:PTZ00121 1710 KEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIrkeKEAVIEEELDEED 1789
|
...
gi 313104325 760 EER 762
Cdd:PTZ00121 1790 EKR 1792
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1402-1668 |
2.66e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.03 E-value: 2.66e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1402 KQQDKAL-------EQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPK 1474
Cdd:COG1196 207 RQAEKAEryrelkeELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEA 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1475 DKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQK 1554
Cdd:COG1196 287 QAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1555 YWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAR 1634
Cdd:COG1196 367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446
|
250 260 270
....*....|....*....|....*....|....
gi 313104325 1635 EQEEKYWRGQDVVQEWQETSPTREEPAGEQKELA 1668
Cdd:COG1196 447 AAEEEAELEEEEEALLELLAELLEEAALLEAALA 480
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
1399-1550 |
3.05e-09 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 62.49 E-value: 3.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1399 EAVKQQDKALEQKGRDLE--QKDTALEQKDKALEPK---DKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEP 1473
Cdd:PRK12704 35 EAEEEAKRILEEAKKEAEaiKKEALLEAKEEIHKLRnefEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEK 114
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 313104325 1474 KDKDLEQKDRVLEQKEkipEEKDKALDQKVRSVEHKApEDTVAEMKDRDLEQTDKapEQKHQAQEQ-KDKVSEKKDQA 1550
Cdd:PRK12704 115 KEKELEQKQQELEKKE---EELEELIEEQLQELERIS-GLTAEEAKEILLEKVEE--EARHEAAVLiKEIEEEAKEEA 186
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1349-1745 |
9.30e-09 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 61.52 E-value: 9.30e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1349 LKDRTSEQKKEPEPKDEVLQQKdkTLEHKEVVEPKDTAIYQKDEALHVKneaVKQQDKALEQKGRDLEQKDTALEQKDKA 1428
Cdd:TIGR00618 417 SAFRDLQGQLAHAKKQQELQQR--YAELCAAAITCTAQCEKLEKIHLQE---SAQSLKEREQQLQTKEQIHLQETRKKAV 491
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1429 LEPKDKDLEEKDKALEQKDKIPEEK--DKALEQKDT----ALEQKDKALEPKDKDLE-QKDRVLEQ----KEKIPEEKD- 1496
Cdd:TIGR00618 492 VLARLLELQEEPCPLCGSCIHPNPArqDIDNPGPLTrrmqRGEQTYAQLETSEEDVYhQLTSERKQraslKEQMQEIQQs 571
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1497 -KALDQKVRSVEHKAP-----EDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQkywalGQKDEAleqniQ 1570
Cdd:TIGR00618 572 fSILTQCDNRSKEDIPnlqniTVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHL-----QQCSQE-----L 641
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1571 ALEENHQTQEQESLVQED---KTRKPKMLEEKSPEKVKAMEEKLEALLEKTKAL--GLEESLVQEGRAREQEEKYWRgqd 1645
Cdd:TIGR00618 642 ALKLTALHALQLTLTQERvreHALSIRVLPKELLASRQLALQKMQSEKEQLTYWkeMLAQCQTLLRELETHIEEYDR--- 718
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1646 VVQEWQETSPT-------REEPAGE-QKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWRELSCERKVWFPHELdgQGA 1717
Cdd:TIGR00618 719 EFNEIENASSSlgsdlaaREDALNQsLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRL--REE 796
|
410 420
....*....|....*....|....*...
gi 313104325 1718 RPHYTEERESTFLDEGPDDEQEVPLREH 1745
Cdd:TIGR00618 797 DTHLLKTLEAEIGQEIPSDEDILNLQCE 824
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1423-1639 |
9.67e-09 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 61.53 E-value: 9.67e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1423 EQKDKALEPKDkdlEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQK 1502
Cdd:pfam02463 169 RKKKEALKKLI---EETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1503 VRSVEH-----KAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQ 1577
Cdd:pfam02463 246 LRDEQEeiessKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 313104325 1578 TQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQE-GRAREQEEK 1639
Cdd:pfam02463 326 AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKkKLESERLSS 388
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1347-1639 |
9.82e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 61.31 E-value: 9.82e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1347 PGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKD 1426
Cdd:PTZ00121 1074 PSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKR 1153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1427 KALEPKDKD---------------LEEKDKAL-----------------------EQKDKIPE----EKDKALEQKDTAL 1464
Cdd:PTZ00121 1154 VEIARKAEDarkaeearkaedakkAEAARKAEevrkaeelrkaedarkaeaarkaEEERKAEEarkaEDAKKAEAVKKAE 1233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1465 EQKDKALEPKDKDLEQKDRVLEQKEKIP-------------EEKDKALD----QKVRSVEH--KAPEDTVAEMKDRDLEQ 1525
Cdd:PTZ00121 1234 EAKKDAEEAKKAEEERNNEEIRKFEEARmahfarrqaaikaEEARKADElkkaEEKKKADEakKAEEKKKADEAKKKAEE 1313
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1526 TDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEAlEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVK 1605
Cdd:PTZ00121 1314 AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEA-EAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK 1392
|
330 340 350
....*....|....*....|....*....|....
gi 313104325 1606 AMEEKLEALLEKTKALGLEESLVQEGRAREQEEK 1639
Cdd:PTZ00121 1393 ADEAKKKAEEDKKKADELKKAAAAKKKADEAKKK 1426
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1369-1667 |
1.14e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 61.24 E-value: 1.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1369 QKDKTLEHKEVVEpkdtaiyQKDEALHVKNEAVKQQDKALEqkgrdlEQKDTALEQKDKALEPKDKDLEEKDKALEQKDK 1448
Cdd:TIGR02169 171 KKEKALEELEEVE-------ENIERLDLIIDEKRQQLERLR------REREKAERYQALLKEKREYEGYELLKEKEALER 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1449 IPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQK----EKIPEEKDKALDQKVRSVEHKAP--EDTVAEMKDRd 1522
Cdd:TIGR02169 238 QKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELnkkiKDLGEEEQLRVKEKIGELEAEIAslERSIAEKERE- 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1523 LEQTDkapEQKHQAQEQKDKVSEKKDQ-------------ALEQKYWALGQKDEALEQNIQALEENHQT--QEQESLVQ- 1586
Cdd:TIGR02169 317 LEDAE---ERLAKLEAEIDKLLAEIEElereieeerkrrdKLTEEYAELKEELEDLRAELEEVDKEFAEtrDELKDYREk 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1587 -EDKTRK--------PKMLEEKS--PEKVKAMEEKLEALLEKTKALGLE-ESLVQEGRAREQEEKYWRgQDVVQEWQETS 1654
Cdd:TIGR02169 394 lEKLKREinelkrelDRLQEELQrlSEELADLNAAIAGIEAKINELEEEkEDKALEIKKQEWKLEQLA-ADLSKYEQELY 472
|
330
....*....|...
gi 313104325 1655 PTREEPAGEQKEL 1667
Cdd:TIGR02169 473 DLKEEYDRVEKEL 485
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1397-1587 |
2.02e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 59.78 E-value: 2.02e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1397 KNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDtaLEQKDKALEPKDK 1476
Cdd:COG4717 65 KPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLP--LYQELEALEAELA 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1477 DLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKApEDTVAEMKDRDLEqtdkAPEQKHQAQEQKDKVSEKKdQALEQKYW 1556
Cdd:COG4717 143 ELPERLEELEERLEELRELEEELEELEAELAELQ-EELEELLEQLSLA----TEEELQDLAEELEELQQRL-AELEEELE 216
|
170 180 190
....*....|....*....|....*....|.
gi 313104325 1557 ALGQKDEALEQNIQALEENHQTQEQESLVQE 1587
Cdd:COG4717 217 EAQEELEELEEELEQLENELEAAALEERLKE 247
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1292-1629 |
2.16e-08 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 59.98 E-value: 2.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1292 SFSHSTPSGNGKYLPGAITSPDEHILTPDSSFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSEQK-------------K 1358
Cdd:TIGR00618 509 SCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSIltqcdnrskedipN 588
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1359 EPEPKDEVLQQKDKTLEHKEvvepkdtaiyQKDEALHV----KNEAVKQQDKALE--QKGRDLEQKDTALEQ-------- 1424
Cdd:TIGR00618 589 LQNITVRLQDLTEKLSEAED----------MLACEQHAllrkLQPEQDLQDVRLHlqQCSQELALKLTALHAlqltltqe 658
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1425 ----------------------KDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKD 1482
Cdd:TIGR00618 659 rvrehalsirvlpkellasrqlALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAARE 738
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1483 RVLEQ-KEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPE-QKHQAQEQKDKVSEKKDQALEQKYWALGQ 1560
Cdd:TIGR00618 739 DALNQsLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQfFNRLREEDTHLLKTLEAEIGQEIPSDEDI 818
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 313104325 1561 KDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQ 1629
Cdd:TIGR00618 819 LNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQ 887
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1401-1640 |
2.17e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.07 E-value: 2.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1401 VKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQ 1480
Cdd:TIGR02168 234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1481 KDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEmKDRDLEQtDKAPEQKHQAQEQKDKVSEKKDQALEQ--KYWAL 1558
Cdd:TIGR02168 314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELK-EELESLE-AELEELEAELEELESRLEELEEQLETLrsKVAQL 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1559 GQKDEA-------LEQNIQALEENHQ--TQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQ 1629
Cdd:TIGR02168 392 ELQIASlnneierLEARLERLEDRRErlQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELE 471
|
250
....*....|.
gi 313104325 1630 EGRAREQEEKY 1640
Cdd:TIGR02168 472 EAEQALDAAER 482
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1389-1584 |
2.77e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 59.40 E-value: 2.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1389 QKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDkiPEEKDKALEQKDTALEQKD 1468
Cdd:COG4717 71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLP--LYQELEALEAELAELPERL 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1469 KALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVehkaPEDTVAEMKDrDLEQTDKAPEQKHQAQEQKDKVSEKKD 1548
Cdd:COG4717 149 EELEERLEELRELEEELEELEAELAELQEELEELLEQL----SLATEEELQD-LAEELEELQQRLAELEEELEEAQEELE 223
|
170 180 190
....*....|....*....|....*....|....*.
gi 313104325 1549 QALEQKywalgqkdEALEQNIQALEENHQTQEQESL 1584
Cdd:COG4717 224 ELEEEL--------EQLENELEAAALEERLKEARLL 251
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
1335-1794 |
3.76e-08 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 59.35 E-value: 3.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1335 LEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLE--------HKEVVEPKDTAIYQKDEALHVKNEAVKQQDK 1406
Cdd:pfam05483 298 LEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEelnkakaaHSFVVTEFEATTCSLEELLRTEQQRLEKNED 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1407 ALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKdKALEQKDTALEQKDKAL-------EPKDKDLE 1479
Cdd:pfam05483 378 QLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEK-KQFEKIAEELKGKEQELifllqarEKEIHDLE 456
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1480 QKDRVLEQKE-----KIPEEKDKALDQKVRSVEHKAPEDTVA-EMKDRDLEQTDKAPEQKHQAQE-------------QK 1540
Cdd:pfam05483 457 IQLTAIKTSEehylkEVEDLKTELEKEKLKNIELTAHCDKLLlENKELTQEASDMTLELKKHQEDiinckkqeermlkQI 536
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1541 DKVSEKKDQ---ALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEdktRKPKMLEEKSPEKVKAMEEK---LEAL 1614
Cdd:pfam05483 537 ENLEEKEMNlrdELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKE---KQMKILENKCNNLKKQIENKnknIEEL 613
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1615 LEKTKALGLEESL------VQEGRAREQE-------EKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDtspeqdnr 1681
Cdd:pfam05483 614 HQENKALKKKGSAenkqlnAYEIKVNKLElelasakQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIAD-------- 685
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1682 ywrgrEDVALEQDTywrELSCERKVW--------FPHELDgqgarpHYTEERESTfLDEGPDDEQEvplrEHATRSPWAS 1753
Cdd:pfam05483 686 -----EAVKLQKEI---DKRCQHKIAemvalmekHKHQYD------KIIEERDSE-LGLYKNKEQE----QSSAKAALEI 746
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 313104325 1754 DFKDFQES--SPQKGLEVERwlaespvglppEEEDKLTRSPFE 1794
Cdd:pfam05483 747 ELSNIKAEllSLKKQLEIEK-----------EEKEKLKMEAKE 778
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1352-1640 |
7.05e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 58.54 E-value: 7.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1352 RTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQ-KDEALHVKNEAVKQQDKALEQKGRDLEQkdtaLEQKDKALE 1430
Cdd:PRK03918 463 RIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKElAEQLKELEEKLKKYNLEELEKKAEEYEK----LKEKLIKLK 538
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1431 PKDKDLE---EKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKD-KDLEQKDRVLEQKEKIPEEKDKALDQKVRSV 1506
Cdd:PRK03918 539 GEIKSLKkelEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESvEELEERLKELEPFYNEYLELKDAEKELEREE 618
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1507 EHKAPEDTVAEMKDRDLEQTDKAPEQ-KHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQ--ES 1583
Cdd:PRK03918 619 KELKKLEEELDKAFEELAETEKRLEElRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKtlEK 698
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 313104325 1584 LVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGR-ARE-----QEEKY 1640
Cdd:PRK03918 699 LKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGEiASEifeelTEGKY 761
|
|
| tolA |
PRK09510 |
cell envelope integrity inner membrane protein TolA; Provisional |
1400-1564 |
8.11e-08 |
|
cell envelope integrity inner membrane protein TolA; Provisional
Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 57.12 E-value: 8.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1400 AVKQQDKALEQKGRDLEQKDTALEQKDKALEpkdkdlEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALE-PKDKDL 1478
Cdd:PRK09510 77 AEEQRKKKEQQQAEELQQKQAAEQERLKQLE------KERLAAQEQKKQAEEAAKQAALKQKQAEEAAAKAAAaAKAKAE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1479 EQKDRVLEQKEKIPEEKDK-ALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEqkhQAQEQKDKVSEKKDQALEQKYWA 1557
Cdd:PRK09510 151 AEAKRAAAAAKKAAAEAKKkAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKKKAE---AEAKKKAAAEAKKKAAAEAKAAA 227
|
....*..
gi 313104325 1558 LGQKDEA 1564
Cdd:PRK09510 228 AKAAAEA 234
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1777-2149 |
8.69e-08 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 58.26 E-value: 8.69e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1777 PVGLPPEEEDKLTRSPFEIISPPASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAP 1856
Cdd:PHA03307 72 PPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAAS 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1857 LSPAPGPPTPAPESH-TPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDY---RKAEGEREEEGRAEAPDKSSHSS 1932
Cdd:PHA03307 152 PPAAGASPAAVASDAaSSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRpprRSSPISASASSPAPAPGRSAADD 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1933 KVPEASKShATTEPEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTS 2012
Cdd:PHA03307 232 AGASSSDS-SSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPS 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2013 AEKELSSPISPKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSP-PLNGNILSCSPDRRSP 2091
Cdd:PHA03307 311 SPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRaPSSPAASAGRPTRRRA 390
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2092 SPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPT--LWPETEahvSPP 2149
Cdd:PHA03307 391 RAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYARYPLLTPSgePWPGSP---PPP 447
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1343-1639 |
1.13e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 57.77 E-value: 1.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1343 EDKVPGLKDRTSEQKKEPE----PKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQK 1418
Cdd:TIGR02169 673 PAELQRLRERLEGLKRELSslqsELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQE 752
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1419 DTALEQKDKALEPKDKDLEEK-------DKALEQK------DKIPEEKDK-------------ALEQKDTALEQKDKALE 1472
Cdd:TIGR02169 753 IENVKSELKELEARIEELEEDlhkleeaLNDLEARlshsriPEIQAELSKleeevsriearlrEIEQKLNRLTLEKEYLE 832
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1473 PKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEdtvAEMKDRDLE--------QTDKAPEQKHQAQ----EQK 1540
Cdd:TIGR02169 833 KEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEE---LEAALRDLEsrlgdlkkERDELEAQLRELErkieELE 909
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1541 DKVSEKKDQALEQKywalgQKDEALEQNIQALEENHQTQEQESlvqedktrKPKMLEEKSPEKVKAMEEKLEAlLEKTKA 1620
Cdd:TIGR02169 910 AQIEKKRKRLSELK-----AKLEALEEELSEIEDPKGEDEEIP--------EEELSLEDVQAELQRVEEEIRA-LEPVNM 975
|
330
....*....|....*....
gi 313104325 1621 LGLEESLVQEGRAREQEEK 1639
Cdd:TIGR02169 976 LAIQEYEEVLKRLDELKEK 994
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1320-1639 |
1.47e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 57.46 E-value: 1.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1320 DSSFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSEQKKEPEPK---------DEVLQQKD--KTLEHKEVVEPKDTAIY 1388
Cdd:PTZ00121 1078 DFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKkkaedarkaEEARKAEDarKAEEARKAEDAKRVEIA 1157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1389 QKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKdKALEPKDkdLEEKDKAlEQKDKIpEEKDKALEQKDTALEQKD 1468
Cdd:PTZ00121 1158 RKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELR-KAEDARK--AEAARKA-EEERKA-EEARKAEDAKKAEAVKKA 1232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1469 KALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEmKDRDLEQTDKAPEQKhqAQEQKDKVSEKKD 1548
Cdd:PTZ00121 1233 EEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKAD-ELKKAEEKKKADEAK--KAEEKKKADEAKK 1309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1549 QALE-QKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEAllEKTKALGLEESL 1627
Cdd:PTZ00121 1310 KAEEaKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE--AKKKADAAKKKA 1387
|
330
....*....|..
gi 313104325 1628 VQEGRAREQEEK 1639
Cdd:PTZ00121 1388 EEKKKADEAKKK 1399
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1402-1682 |
1.74e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.37 E-value: 1.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1402 KQQDKALEQKgrdlEQKDtALEQKDKAL-----EPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDK 1476
Cdd:TIGR02168 207 RQAEKAERYK----ELKA-ELRELELALlvlrlEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEE 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1477 DL-EQKDRVLEQKEKIpeekdKALDQKVRsvEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQaLEQKY 1555
Cdd:TIGR02168 282 EIeELQKELYALANEI-----SRLEQQKQ--ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE-LKEEL 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1556 WALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEAL-------LEKTKALGLEESLV 1628
Cdd:TIGR02168 354 ESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLedrrerlQQEIEELLKKLEEA 433
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 313104325 1629 QEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRY 1682
Cdd:TIGR02168 434 ELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1381-1639 |
2.51e-07 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 55.68 E-value: 2.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1381 EPKDTAIYQKDEA---LHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKdkipEEKDKAL 1457
Cdd:COG4372 31 EQLRKALFELDKLqeeLEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQA----QEELESL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1458 EQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPE----EKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTD---KAP 1530
Cdd:COG4372 107 QEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQseiaEREEELKELEEQLESLQEELAALEQELQALSEAEaeqALD 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1531 EQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIqalEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEK 1610
Cdd:COG4372 187 ELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKD---SLEAKLGLALSALLDALELEEDKEELLEEVILKEIEEL 263
|
250 260
....*....|....*....|....*....
gi 313104325 1611 LEALLEKTKALGLEESLVQEGRAREQEEK 1639
Cdd:COG4372 264 ELAILVEKDTEEEELEIAALELEALEEAA 292
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
1355-1519 |
2.78e-07 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 55.94 E-value: 2.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1355 EQKKEPEP--KDEVLQQKDKTLEHKEVVEpkdtaiyqKDeaLHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPK 1432
Cdd:PRK12704 46 EAKKEAEAikKEALLEAKEEIHKLRNEFE--------KE--LRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKK 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1433 DKDLEEKDKALEQKDkipEEKDKALEQKDTALEQ-----KDKAlepkdkdleqKDRVLEQ-KEKIPEEKDKaldqKVRSV 1506
Cdd:PRK12704 116 EKELEQKQQELEKKE---EELEELIEEQLQELERisgltAEEA----------KEILLEKvEEEARHEAAV----LIKEI 178
|
170
....*....|...
gi 313104325 1507 EHKAPEDtvAEMK 1519
Cdd:PRK12704 179 EEEAKEE--ADKK 189
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
2036-2441 |
4.20e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 55.95 E-value: 4.20e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2036 AALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPilskgpsPPLNGNILSCSPDRRSPSPKESGRShwddstsdselekgar 2115
Cdd:PHA03307 56 VAGAAACDRFEPPTGPPPGPGTEAPANESRST-------PTWSLSTLAPASPAREGSPTPPGPS---------------- 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2116 eQPEKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFPASAFGFSSlqPAPPQLPSPAEPRSAPCGSLA 2195
Cdd:PHA03307 113 -SPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAAS--SRQAALPLSSPEETARAPSSP 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2196 fSGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPqLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAeRF 2275
Cdd:PHA03307 190 -PAEPPPSTPPAAASPRPPRRSSPISASASSPAPAP-GRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPIT-LP 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2276 SPSLEAAEQESGELDPGMEPAAHSLWDLTPlSPAPPASLDLALAPAPSLPGDMGDGilpchlecSEAATEKPSPFQVPSE 2355
Cdd:PHA03307 267 TRIWEASGWNGPSSRPGPASSSSSPRERSP-SPSPSSPGSGPAPSSPRASSSSSSS--------RESSSSSTSSSSESSR 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2356 DCA-------ANGPTETSPNPPGPAPAKAENEEAAACPAWERGAWPEGAERSSRPDTL-LSPEQPVCPAGGSGGPPSSAS 2427
Cdd:PHA03307 338 GAAvspgpspSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAgRARRRDATGRFPAGRPRPSPL 417
|
410
....*....|....
gi 313104325 2428 PEVEAGPQGCATEP 2441
Cdd:PHA03307 418 DAGAASGAFYARYP 431
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
1336-1566 |
5.28e-07 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 55.35 E-value: 5.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1336 EDIAIKWEDKVPGLKDRTSEQkkEPEPKDEVLQQKDKTLEH--KEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGR 1413
Cdd:COG5185 350 ESLTENLEAIKEEIENIVGEV--ELSKSSEELDSFKDTIEStkESLDEIPQNQRGYAQEILATLEDTLKAADRQIEELQR 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1414 DLEQKDTALEQKDKALEPKDKDLEEKDKaleqkdKIPEEKDKALEQKDTALEQKDKA-LEPKDKDLEQ-KDRVLEQKEKI 1491
Cdd:COG5185 428 QIEQATSSNEEVSKLLNELISELNKVMR------EADEESQSRLEEAYDEINRSVRSkKEDLNEELTQiESRVSTLKATL 501
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1492 PEEKDKALDQ--KVRSVEHKAPEDTVAEMKDRDLEQtDKAPEQKHQAQEQKDKVSEKKDQALEQKYWA----LGQKDEAL 1565
Cdd:COG5185 502 EKLRAKLERQleGVRSKLDQVAESLKDFMRARGYAH-ILALENLIPASELIQASNAKTDGQAANLRTAvideLTQYLSTI 580
|
.
gi 313104325 1566 E 1566
Cdd:COG5185 581 E 581
|
|
| RNase_Y_N |
pfam12072 |
RNase Y N-terminal region; |
1392-1550 |
5.46e-07 |
|
RNase Y N-terminal region;
Pssm-ID: 463456 [Multi-domain] Cd Length: 201 Bit Score: 52.58 E-value: 5.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1392 EALHVKNEAVKQQDKAleQKGRDLEQKDTALEQKDKAlepkDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKAL 1471
Cdd:pfam12072 35 LAKRIIEEAKKEAETK--KKEALLEAKEEIHKLRAEA----ERELKERRNELQRQERRLLQKEETLDRKDESLEKKEESL 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1472 EPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEhkapEDTVAEMKDRDLEQTDKapEQKHQAQEQ-KDKVSEKKDQA 1550
Cdd:pfam12072 109 EKKEKELEAQQQQLEEKEEELEELIEEQRQELERIS----GLTSEEAKEILLDEVEE--ELRHEAAVMiKEIEEEAKEEA 182
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1994-2323 |
7.68e-07 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 54.92 E-value: 7.68e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1994 GDWPPCLSTKEAAAGRNTSAEKELSSPiSPKSlQSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGP 2073
Cdd:pfam05109 397 GTAPKTLIITRTATNATTTTHKVIFSK-APES-TTTSPTLNTTGFAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTADVT 474
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2074 SPPLNGNILSCSPDRRSPSPKESG-RSHWDDSTSDSElekgAREQPEKEAQSPSPPHPIPmgSPTLWPETEAHVSPplDS 2152
Cdd:pfam05109 475 SPTPAGTTSGASPVTPSPSPRDNGtESKAPDMTSPTS----AVTTPTPNATSPTPAVTTP--TPNATSPTLGKTSP--TS 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2153 HLGPARPSLDFPASAfgfssLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPG---PPTRTRHDEYLEVTKAPSLDSS 2229
Cdd:pfam05109 547 AVTTPTPNATSPTPA-----VTTPTPNATIPTLGKTSPTSAVTTPTPNATSPTVGetsPQANTTNHTLGGTSSTPVVTSP 621
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2230 LPQLPSPSSPGAPLLSNlPRPASPALSEGSSSEATTPVISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPA 2309
Cdd:pfam05109 622 PKNATSAVTTGQHNITS-SSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSSPA 700
|
330
....*....|....*
gi 313104325 2310 P-PASLDLALAPAPS 2323
Cdd:pfam05109 701 PrPGTTSQASGPGNS 715
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1385-1649 |
7.97e-07 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 54.14 E-value: 7.97e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1385 TAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTAL 1464
Cdd:COG4372 24 ILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEEL 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1465 EQKDKALEPKDKDLEQkdrvLEQKEKIPEEKDKALDQKVRSVEHKAPEdtvaemKDRDLEQ-TDKAPEQKHQAQEQKDKV 1543
Cdd:COG4372 104 ESLQEEAEELQEELEE----LQKERQDLEQQRKQLEAQIAELQSEIAE------REEELKElEEQLESLQEELAALEQEL 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1544 SEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVkamEEKLEALLEKTKALGL 1623
Cdd:COG4372 174 QALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLA---LSALLDALELEEDKEE 250
|
250 260
....*....|....*....|....*.
gi 313104325 1624 EESLVQEGRAREQEEKYWRGQDVVQE 1649
Cdd:COG4372 251 LLEEVILKEIEELELAILVEKDTEEE 276
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1350-1661 |
1.07e-06 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 54.36 E-value: 1.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1350 KDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVK----------------NEAVKQQDKALE-QKG 1412
Cdd:pfam17380 298 QERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMErerelerirqeerkreLERIRQEEIAMEiSRM 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1413 RDLEQKDTALEQKDKALEP------KDKDLEEKDKALEQKDKIPEEKDKAlEQKDTALEQKDKALEPKDKDLEQ-KDRVL 1485
Cdd:pfam17380 378 RELERLQMERQQKNERVRQeleaarKVKILEEERQRKIQQQKVEMEQIRA-EQEEARQREVRRLEEERAREMERvRLEEQ 456
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1486 EQKEKIPEEKDKALDQKVRSVE---HKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKD 1562
Cdd:pfam17380 457 ERQQQVERLRQQEEERKRKKLElekEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRR 536
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1563 EALEQ--NIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESL----VQEGRAREQ 1636
Cdd:pfam17380 537 EAEEErrKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYEATTPITTIKPIyrprISEYQPPDV 616
|
330 340
....*....|....*....|....*
gi 313104325 1637 EEKYWRGQDVVQEWQETSPTREEPA 1661
Cdd:pfam17380 617 ESHMIRFTTQSPEWATPSPATWNPE 641
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1430-1693 |
1.23e-06 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 53.37 E-value: 1.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1430 EPKDKDLEEKDKALEQKDKIPEEKDKA---LEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEkipeEKDKALDQKVRSV 1506
Cdd:COG4372 31 EQLRKALFELDKLQEELEQLREELEQAreeLEQLEEELEQARSELEQLEEELEELNEQLQAAQ----AELAQAQEELESL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1507 EHKApEDTVAEMKDRDLEQTDKApEQKHQAQEQKDKVSEK---KDQALEQkywaLGQKDEALEQNIQALEENHQTQEQES 1583
Cdd:COG4372 107 QEEA-EELQEELEELQKERQDLE-QQRKQLEAQIAELQSEiaeREEELKE----LEEQLESLQEELAALEQELQALSEAE 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1584 LVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQE-WQETSPTREEPAG 1662
Cdd:COG4372 181 AEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEdKEELLEEVILKEI 260
|
250 260 270
....*....|....*....|....*....|.
gi 313104325 1663 EQKELAPAWEDTSPEQDNRYWRGREDVALEQ 1693
Cdd:COG4372 261 EELELAILVEKDTEEEELEIAALELEALEEA 291
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1419-1663 |
1.62e-06 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 53.30 E-value: 1.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1419 DTALEQKDKALepkDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKAlepkDKDLEQKDRVLEQKEKIPEEKDKA 1498
Cdd:COG3883 15 DPQIQAKQKEL---SELQAELEAAQAELDALQAELEELNEEYNELQAELEAL----QAEIDKLQAEIAEAEAEIEERREE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1499 LDQKVRS--------------VEHKAPED------TVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWAL 1558
Cdd:COG3883 88 LGERARAlyrsggsvsyldvlLGSESFSDfldrlsALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELE 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1559 GQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEE 1638
Cdd:COG3883 168 AAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAA 247
|
250 260
....*....|....*....|....*
gi 313104325 1639 KYWRGQDVVQEWQETSPTREEPAGE 1663
Cdd:COG3883 248 GAGAAGAAGAAAGSAGAAGAAAGAA 272
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1408-1640 |
1.68e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.91 E-value: 1.68e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1408 LEQKGRDLEQKDTALEQKDKALEpkdKDLEEKDKALEQKDKIPEEKD----------KALEQKDTALEQKDKALEPKDKD 1477
Cdd:TIGR02168 682 LEEKIEELEEKIAELEKALAELR---KELEELEEELEQLRKELEELSrqisalrkdlARLEAEVEQLEERIAQLSKELTE 758
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1478 LEQKDRVLEQKEKIPEEKDKALDQKVRSVehkapEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEK--KDQALEQKY 1555
Cdd:TIGR02168 759 LEAEIEELEERLEEAEEELAEAEAEIEEL-----EAQIEQLKEELKALREALDELRAELTLLNEEAANLreRLESLERRI 833
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1556 WALGQKDEALEQNIQALEENhqtQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRARE 1635
Cdd:TIGR02168 834 AATERRLEDLEEQIEELSED---IESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKR 910
|
....*
gi 313104325 1636 QEEKY 1640
Cdd:TIGR02168 911 SELRR 915
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
1356-1619 |
1.78e-06 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 53.67 E-value: 1.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1356 QKKePEPKDEVLQQKDKTLEH-KEVVEPKDTAIYQKDEALHVKNEAVKQQDKALE----QKGRDLEQKDTALEQKDKALe 1430
Cdd:pfam10174 400 QKK-IENLQEQLRDKDKQLAGlKERVKSLQTDSSNTDTALTTLEEALSEKERIIErlkeQREREDRERLEELESLKKEN- 477
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1431 pkdKDLEEKDKALeQKDKIPEEKdKALEQKDTALEQKDKALEpKDKDLEQKDRVLEQKEkipEEKDKALDQKVRSVEHKA 1510
Cdd:pfam10174 478 ---KDLKEKVSAL-QPELTEKES-SLIDLKEHASSLASSGLK-KDSKLKSLEIAVEQKK---EECSKLENQLKKAHNAEE 548
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1511 PEDTVAEMKDR--DLEQ-TDKAPEQKHQAQEQKDKV--------SEKKDQAleqkywalgQKDEALEQNI--QALEENHQ 1577
Cdd:pfam10174 549 AVRTNPEINDRirLLEQeVARYKEESGKAQAEVERLlgilreveNEKNDKD---------KKIAELESLTlrQMKEQNKK 619
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 313104325 1578 TQEQESLVQEDKTRKPKMLEEKSPEKVKAME-------EKLEALLEKTK 1619
Cdd:pfam10174 620 VANIKHGQQEMKKKGAQLLEEARRREDNLADnsqqlqlEELMGALEKTR 668
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1302-1652 |
2.06e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.52 E-value: 2.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1302 GKYLPGA-ITSPDEHILTPDSSFSKSPESLPGPALE-DIAIKwedkvpglkdRTSEQKKEPEPKDEVLQQKDKTLEHK-- 1377
Cdd:TIGR02168 639 KKLRPGYrIVTLDGDLVRPGGVITGGSAKTNSSILErRREIE----------ELEEKIEELEEKIAELEKALAELRKEle 708
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1378 ---EVVEPKDTAIYQKDEALHvkneAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEK-----DKALEQKDKI 1449
Cdd:TIGR02168 709 eleEELEQLRKELEELSRQIS----ALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERleeaeEELAEAEAEI 784
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1450 PEEKDKALEQKDtALEQKDKALEPKDKDL-EQKDRVLEQKEKIPEEKDKALDQKVRSvehkapEDTVAEMKDRDLEQTDK 1528
Cdd:TIGR02168 785 EELEAQIEQLKE-ELKALREALDELRAELtLLNEEAANLRERLESLERRIAATERRL------EDLEEQIEELSEDIESL 857
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1529 APEQKHQaQEQKDKVSEKKDQALEQKywalgqkdEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAME 1608
Cdd:TIGR02168 858 AAEIEEL-EELIEELESELEALLNER--------ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 313104325 1609 EKLEALleKTKALGLEESLVQEGR--AREQEEKYWRGQDVVQEWQE 1652
Cdd:TIGR02168 929 LRLEGL--EVRIDNLQERLSEEYSltLEEAEALENKIEDDEEEARR 972
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1407-1617 |
2.32e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.46 E-value: 2.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1407 ALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLE 1486
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1487 QKEkipEEKDKALDQKVRSVEHKAPEDTVAE-MKDRDLEQTDK--------APEQKHQAQEQKDKVSE--KKDQALEQKY 1555
Cdd:COG4942 97 AEL---EAQKEELAELLRALYRLGRQPPLALlLSPEDFLDAVRrlqylkylAPARREQAEELRADLAElaALRAELEAER 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 313104325 1556 WALGQKDEALEQNIQALEEnhQTQEQESLVQEDKTRKPKmlEEKSPEKVKAMEEKLEALLEK 1617
Cdd:COG4942 174 AELEALLAELEEERAALEA--LKAERQKLLARLEKELAE--LAAELAELQQEAEELEALIAR 231
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
1977-2268 |
2.35e-06 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 53.62 E-value: 2.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1977 TGLGPACPTREPP---LGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPTFSYAALAGPTVP----PRPEP 2049
Cdd:pfam03154 178 SGAASPPSPPPPGttqAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPlqpmTQPPP 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2050 GPSMEPSLTPPAV-----PPRAPILSKGPS------PPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQP 2118
Cdd:pfam03154 258 PSQVSPQPLPQPSlhgqmPPMPHSLQTGPShmqhpvPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQ 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2119 EKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFPasaFGFSSLQPAPP------QLPSPAEPRSAPCG 2192
Cdd:pfam03154 338 QPPREQPLPPAPLSMPHIKPPPTTPIPQLPNPQSHKHPPHLSGPSP---FQMNSNLPPPPalkplsSLSTHHPPSAHPPP 414
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 313104325 2193 SLAFSGDRALALAPGPPTRTRHDEYLEVTKA--PSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVI 2268
Cdd:pfam03154 415 LQLMPQSQQLPPPPAQPPVLTQSQSLPPPAAshPPTSGLHQVPSQSPFPQHPFVPGGPPPITPPSGPPTSTSSAMPGI 492
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
1415-1640 |
2.51e-06 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 53.21 E-value: 2.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1415 LEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKdlEQKDRVlEQKEKIPEE 1494
Cdd:pfam05557 11 LSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALR--EQAELN-RLKKKYLEA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1495 KDKALDQKvrsvehkapEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEK----------------KDQALEQKYWAL 1558
Cdd:pfam05557 88 LNKKLNEK---------ESQLADAREVISCLKNELSELRRQIQRAELELQSTnseleelqerldllkaKASEAEQLRQNL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1559 GQKDEAL---EQNIQALEENHQTQEQESLV----QEDKTRKPKMLEEKspEKVKAMEEKLEALLEkTKALgLEESLVQEG 1631
Cdd:pfam05557 159 EKQQSSLaeaEQRIKELEFEIQSQEQDSEIvknsKSELARIPELEKEL--ERLREHNKHLNENIE-NKLL-LKEEVEDLK 234
|
....*....
gi 313104325 1632 RAREQEEKY 1640
Cdd:pfam05557 235 RKLEREEKY 243
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1349-1618 |
2.81e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.15 E-value: 2.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1349 LKDRTSEQKKEPEPKDEVLQQKDKTLEHKEV----VEPKDTAIYQKDeaLHVKNEAVKQQDKALEQKGRDLEQKDTALEQ 1424
Cdd:TIGR02169 742 LEEDLSSLEQEIENVKSELKELEARIEELEEdlhkLEEALNDLEARL--SHSRIPEIQAELSKLEEEVSRIEARLREIEQ 819
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1425 KDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLE-QKEKIPEEKDKaLDQKV 1503
Cdd:TIGR02169 820 KLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLEsRLGDLKKERDE-LEAQL 898
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1504 RSVEHKAPE--DTVAEMKDRDLEQTDKAPEQKHQAQE-QKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQE 1580
Cdd:TIGR02169 899 RELERKIEEleAQIEKKRKRLSELKAKLEALEEELSEiEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAI 978
|
250 260 270
....*....|....*....|....*....|....*...
gi 313104325 1581 QEslvQEDKTRKPKMLEEKspeKVKAMEEKlEALLEKT 1618
Cdd:TIGR02169 979 QE---YEEVLKRLDELKEK---RAKLEEER-KAILERI 1009
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
1352-1639 |
3.36e-06 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 52.65 E-value: 3.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1352 RTSEQKKEPEPKDEVLQQKDKTLEHKEVVEP----KDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKdTALEQKDK 1427
Cdd:COG5185 231 IEEALKGFQDPESELEDLAQTSDKLEKLVEQntdlRLEKLGENAESSKRLNENANNLIKQFENTKEKIAEY-TKSIDIKK 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1428 ALEpkdkDLEEKDKALEQKDKIPEEKdkaleqkdtaleqkdkalEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVE 1507
Cdd:COG5185 310 ATE----SLEEQLAAAEAEQELEESK------------------RETETGIQNLTAEIEQGQESLTENLEAIKEEIENIV 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1508 HKAPEDTVAE----MKDRdLEQTDKAPEQKHQAQEQKDKVSEKkdqALEQKYWALGQKDEALEQNI-QALEENHQTQEQ- 1581
Cdd:COG5185 368 GEVELSKSSEeldsFKDT-IESTKESLDEIPQNQRGYAQEILA---TLEDTLKAADRQIEELQRQIeQATSSNEEVSKLl 443
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 313104325 1582 ----ESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEK 1639
Cdd:COG5185 444 neliSELNKVMREADEESQSRLEEAYDEINRSVRSKKEDLNEELTQIESRVSTLKATLEKLR 505
|
|
| RNase_Y_N |
pfam12072 |
RNase Y N-terminal region; |
1488-1640 |
3.42e-06 |
|
RNase Y N-terminal region;
Pssm-ID: 463456 [Multi-domain] Cd Length: 201 Bit Score: 50.27 E-value: 3.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1488 KEKIPEEKDKAldqkvrsveHKAPEDTVAEMKDRDLEqtdkapeqkHQAQE----QKDKVSEKKDQALEQKYWALGQKDE 1563
Cdd:pfam12072 52 KEALLEAKEEI---------HKLRAEAERELKERRNE---------LQRQErrllQKEETLDRKDESLEKKEESLEKKEK 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1564 ALEQNIQALEEnhQTQEQESLVQEDKTRkpkmLEEKS---PEKVKAME-EKLEALLEKTKALGLEESlvqEGRAREQEEK 1639
Cdd:pfam12072 114 ELEAQQQQLEE--KEEELEELIEEQRQE----LERISgltSEEAKEILlDEVEEELRHEAAVMIKEI---EEEAKEEADK 184
|
.
gi 313104325 1640 Y 1640
Cdd:pfam12072 185 K 185
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
1378-1643 |
3.67e-06 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 51.45 E-value: 3.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1378 EVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDL-EEKDKALEQKDKIPEEKDKA 1456
Cdd:COG1340 4 DELSSSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELrEKRDELNEKVKELKEERDEL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1457 LEQKDTALEQKDKaLEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEH-KAPEDTVAEMKDRdLEQTDKAPEQKHQ 1535
Cdd:COG1340 84 NEKLNELREELDE-LRKELAELNKAGGSIDKLRKEIERLEWRQQTEVLSPEEeKELVEKIKELEKE-LEKAKKALEKNEK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1536 AQEQKDKVSEKKDQA--LEQKYWALGQK-DEALEQNIQALEENHQTQEQ-ESLVQE--DKTRKPKMLEEK---SPEKVKA 1606
Cdd:COG1340 162 LKELRAELKELRKEAeeIHKKIKELAEEaQELHEEMIELYKEADELRKEaDELHKEivEAQEKADELHEEiieLQKELRE 241
|
250 260 270
....*....|....*....|....*....|....*...
gi 313104325 1607 MEEKLEALLEKTKALGLEESL-VQEGRAREQEEKYWRG 1643
Cdd:COG1340 242 LRKELKKLRKKQRALKREKEKeELEEKAEEIFEKLKKG 279
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1777-2327 |
3.70e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 53.02 E-value: 3.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1777 PVGLPPEEedklTRSPFEIISPPASPPEMVGQRVPSAPGQESPIPDP---KLMPHMKNEPTTPSWLADIPPWVPKDRPLP 1853
Cdd:PHA03247 2614 PSPLPPDT----HAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPapgRVSRPRRARRLGRAAQASSPPQRPRRRAAR 2689
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1854 PAPLSPAPGPPTPAPESH-TPAPFSWGTAEYDSVVAAVQEGAAeleggPYSPLgkdyrkaegereeegraeapdksshsS 1932
Cdd:PHA03247 2690 PTVGSLTSLADPPPPPPTpEPAPHALVSATPLPPGPAAARQAS-----PALPA--------------------------A 2738
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1933 KVPEASKShATTEPEQTEPEQREPTPYpdersfqyadiyeqmmltglGPACPTrePPLGAAGDwPPCLSTKEAAAGRNTS 2012
Cdd:PHA03247 2739 PAPPAVPA-GPATPGGPARPARPPTTA--------------------GPPAPA--PPAAPAAG-PPRRLTRPAVASLSES 2794
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2013 AEkELSSPISPkslqsdTPTFSYAALAGPTVPPRPEPGPsmePSLTPPAVPPRAPILSKGPSPP---LNGNILSCSPDRR 2089
Cdd:PHA03247 2795 RE-SLPSPWDP------ADPPAAVLAPAAALPPAASPAG---PLPPPTSAQPTAPPPPPGPPPPslpLGGSVAPGGDVRR 2864
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2090 -----SPSPKESGRSHwddstsdSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPsldfp 2164
Cdd:PHA03247 2865 rppsrSPAAKPAAPAR-------PPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPP----- 2932
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2165 asafgfsslQPAPPQLPSPAEPRSAPCGSLAFSG----DRALALAPGPPTRTRhdeylevTKAPsldSSLPQLPSPSSPG 2240
Cdd:PHA03247 2933 ---------PPPPPRPQPPLAPTTDPAGAGEPSGavpqPWLGALVPGRVAVPR-------FRVP---QPAPSREAPASST 2993
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2241 APLLSN-LPRPASPALSEGSSSEATTPVISSVAERFSPS-LEAAEQESGEL-DPGMepaahslWDLTPLSPAPPASLD-L 2316
Cdd:PHA03247 2994 PPLTGHsLSRVSSWASSLALHEETDPPPVSLKQTLWPPDdTEDSDADSLFDsDSER-------SDLEALDPLPPEPHDpF 3066
|
570
....*....|.
gi 313104325 2317 ALAPAPSLPGD 2327
Cdd:PHA03247 3067 AHEPDPATPEA 3077
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
1455-1613 |
4.13e-06 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 52.09 E-value: 4.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1455 KALEQKDTALEQK-DKALEPKDKDLE--QKDRVLEQKEKIPEEKDKaLDQKVRSvehkapedtvaemKDRDLEQTDKAPE 1531
Cdd:PRK12704 27 KIAEAKIKEAEEEaKRILEEAKKEAEaiKKEALLEAKEEIHKLRNE-FEKELRE-------------RRNELQKLEKRLL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1532 QKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQE-----SLVQED-KTRKPKMLEEKSPEK-- 1603
Cdd:PRK12704 93 QKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQElerisGLTAEEaKEILLEKVEEEARHEaa 172
|
170
....*....|....
gi 313104325 1604 --VKAMEE--KLEA 1613
Cdd:PRK12704 173 vlIKEIEEeaKEEA 186
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1412-1616 |
4.56e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 52.35 E-value: 4.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1412 GRDLEQKDTALEQKDKALEPK-DKDLEEKDKALEQK-DKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKE 1489
Cdd:PRK02224 179 ERVLSDQRGSLDQLKAQIEEKeEKDLHERLNGLESElAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEA 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1490 KIPE-EKDKALDQKVR---SVEHKAPEDTVAEMKDR------DLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALG 1559
Cdd:PRK02224 259 EIEDlRETIAETEREReelAEEVRDLRERLEELEEErddllaEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQ 338
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1560 QKD---EALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLE 1616
Cdd:PRK02224 339 AHNeeaESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRE 398
|
|
| Tropomyosin_1 |
pfam12718 |
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and ... |
1397-1540 |
4.65e-06 |
|
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and Tpm2, biochemical and sequence analyses indicate that Tpm2p spans four actin monomers along a filament, whereas Tpm1p spans five. Despite its shorter length, Tpm2p can compete with Tpm1p for binding to F-actin. Over-expression of Tpm2p in vivo alters the axial budding of haploids to a bipolar pattern, and this can be partially suppressed by co-over-expression of Tpm1p. This suggests distinct functions for the two tropomyosins, and indicates that the ratio between them is important for correct morphogenesis. The family also contains higher eukaryote Tpm3 members.
Pssm-ID: 403808 [Multi-domain] Cd Length: 142 Bit Score: 48.45 E-value: 4.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1397 KNEAVKQQDKA--LEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKipEEKDKAlEQKDTALEQKDkalepk 1474
Cdd:pfam12718 6 KLEAENAQERAeeLEEKVKELEQENLEKEQEIKSLTHKNQQLEEEVEKLEEQLK--EAKEKA-EESEKLKTNNE------ 76
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 313104325 1475 dkDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEdtvAEMKDRDLEQTDKAPEQKHQAQEQK 1540
Cdd:pfam12718 77 --NLTRKIQLLEEELEESDKRLKETTEKLRETDVKAEH---LERKVQALEQERDEWEKKYEELEEK 137
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1434-1632 |
5.01e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 52.08 E-value: 5.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1434 KDLEEKDKALE----QKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHK 1509
Cdd:COG4717 49 ERLEKEADELFkpqgRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1510 APEDTVAEMK------DRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQEs 1583
Cdd:COG4717 129 PLYQELEALEaelaelPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQR- 207
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 313104325 1584 lVQEDKTRKpkmleEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGR 1632
Cdd:COG4717 208 -LAELEEEL-----EEAQEELEELEEELEQLENELEAAALEERLKEARL 250
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1397-1598 |
5.10e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 52.08 E-value: 5.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1397 KNEAVK---QQ------DKALEQKGRDLE----QKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTA 1463
Cdd:COG4717 31 PNEAGKstlLAfiramlLERLEKEADELFkpqgRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAE 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1464 LEQKDKALEPKDKDLEQKDRVLEQKEKipEEKDKALDQKVRSVEHKapEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKV 1543
Cdd:COG4717 111 LEELREELEKLEKLLQLLPLYQELEAL--EAELAELPERLEELEER--LEELRELEEELEELEAELAELQEELEELLEQL 186
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 313104325 1544 SEKKDQALEQ---KYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEE 1598
Cdd:COG4717 187 SLATEEELQDlaeELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEER 244
|
|
| tolA |
PRK09510 |
cell envelope integrity inner membrane protein TolA; Provisional |
1348-1550 |
5.65e-06 |
|
cell envelope integrity inner membrane protein TolA; Provisional
Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 51.35 E-value: 5.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1348 GLKDRTSEQKKEPEPKDEVLQQKDKTLEH--KEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQK 1425
Cdd:PRK09510 73 SAKRAEEQRKKKEQQQAEELQQKQAAEQErlKQLEKERLAAQEQKKQAEEAAKQAALKQKQAEEAAAKAAAAAKAKAEAE 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1426 DKALEPKDKDLEEKDKALEQKDKipEEKDKALEQKDTALEQKDKALEpkdkdleqkdrvlEQKEKIPEEKDKALDQkvrs 1505
Cdd:PRK09510 153 AKRAAAAAKKAAAEAKKKAEAEA--AKKAAAEAKKKAEAEAAAKAAA-------------EAKKKAEAEAKKKAAA---- 213
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 313104325 1506 vEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQA 1550
Cdd:PRK09510 214 -EAKKKAAAEAKAAAAKAAAEAKAAAEKAAAAKAAEKAAAAKAAA 257
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
2229-2659 |
6.70e-06 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 52.10 E-value: 6.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2229 SLPQLPSPSSPGAPLlsnlPRPASPALSEGSSSEATTP--VISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPL 2306
Cdd:PHA03307 20 FFPRPPATPGDAADD----LLSGSQGQLVSDSAELAAVtvVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2307 SPAPPASLDLALAPAPSlpgdmgdgilpchlecseaaTEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAACP 2386
Cdd:PHA03307 96 APASPAREGSPTPPGPS--------------------SPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2387 AWERGAWPEGAERSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPqgcATEPRPHRGELSPSFLNPPLPPSIDDRDL 2466
Cdd:PHA03307 156 GASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAAS---PRPPRRSSPISASASSPAPAPGRSAADDA 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2467 STEevrLVGRGGRRRVGGPGTTGGPCPVTDETPPTSasdsgssqsdsdvppeteecPSITAEAALDSDEDGDFLPVDKAG 2546
Cdd:PHA03307 233 GAS---SSDSSSSESSGCGWGPENECPLPRPAPITL--------------------PTRIWEASGWNGPSSRPGPASSSS 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2547 GVSGTH-HPRPGHDPPPLPQPDPRPspprpdvcmADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARrldlr 2625
Cdd:PHA03307 290 SPRERSpSPSPSSPGSGPAPSSPRA---------SSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSR----- 355
|
410 420 430
....*....|....*....|....*....|....*..
gi 313104325 2626 gkrsptpGKGPAD---RASRAPPRPRSTTSQVTPAEE 2659
Cdd:PHA03307 356 -------PPPPADpssPRKRPRPSRAPSSPAASAGRP 385
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
1384-1577 |
6.91e-06 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 52.15 E-value: 6.91e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1384 DTAIYQKDEALHVKNEAVKQ-QDKALEQKGRDLEQKDT------ALEQKDKALEPKDKDLEEKDKALEQK---------- 1446
Cdd:pfam12128 314 DAAVAKDRSELEALEDQHGAfLDADIETAAADQEQLPSwqseleNLEERLKALTGKHQDVTAKYNRRRSKikeqnnrdia 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1447 ------DKIPEEKDKALEQKDTALEQKDKALepKDKDLEQKDRVLEQKEKIpeeKDKALDQKVRSVEHKAPEDTVA--EM 1518
Cdd:pfam12128 394 gikdklAKIREARDRQLAVAEDDLQALESEL--REQLEAGKLEFNEEEYRL---KSRLGELKLRLNQATATPELLLqlEN 468
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 313104325 1519 KDRDLEQTDKAPEQKHQ----AQEQKDKVSEKKDQALEqkywALGQKDEALEQNIQALEENHQ 1577
Cdd:pfam12128 469 FDERIERAREEQEAANAeverLQSELRQARKRRDQASE----ALRQASRRLEERQSALDELEL 527
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
1343-1637 |
7.80e-06 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 51.71 E-value: 7.80e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1343 EDKVPGLKDRTSEQKKEPEPKDEvLQQKDKTLEHKEVVEPK---------DTAIYQKDEALHVKNEAVKQQdkaLEQKGR 1413
Cdd:pfam01576 3 QEEEMQAKEEELQKVKERQQKAE-SELKELEKKHQQLCEEKnalqeqlqaETELCAEAEEMRARLAARKQE---LEEILH 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1414 DLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPE 1493
Cdd:pfam01576 79 ELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1494 EKDKALDQKVRSVEHKAP---------EDTVAEMKDR---------DLEQTDKAPEQkhQAQEQKDKVSEKKDQALEQKY 1555
Cdd:pfam01576 159 ERISEFTSNLAEEEEKAKslsklknkhEAMISDLEERlkkeekgrqELEKAKRKLEG--ESTDLQEQIAELQAQIAELRA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1556 wALGQKDEALE-----------QNIQALEENHQTQEQESLVQEDKTRKpKMLEEKSPEKVKAMEEKLEALleKTKalgLE 1624
Cdd:pfam01576 237 -QLAKKEEELQaalarleeetaQKNNALKKIRELEAQISELQEDLESE-RAARNKAEKQRRDLGEELEAL--KTE---LE 309
|
330
....*....|....*....
gi 313104325 1625 ESL-----VQEGRA-REQE 1637
Cdd:pfam01576 310 DTLdttaaQQELRSkREQE 328
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1336-1649 |
8.31e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 51.58 E-value: 8.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1336 EDIAiKWEDKVPGLKDRTSEQKkepEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALhvkneavkqqDKALEQKGRDL 1415
Cdd:PRK02224 265 ETIA-ETEREREELAEEVRDLR---ERLEELEEERDDLLAEAGLDDADAEAVEARREEL----------EDRDEELRDRL 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1416 EQKDTALEQKDK---ALEPKDKDLEEKDKALEQKdkiPEEKDKALEQKDTALEQKDKALEPKDKDLE-----------QK 1481
Cdd:PRK02224 331 EECRVAAQAHNEeaeSLREDADDLEERAEELREE---AAELESELEEAREAVEDRREEIEELEEEIEelrerfgdapvDL 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1482 DRVLEQKEKIPEEKDkALDQKVRSVEH--KAPEDTVAEmkDRDLEQTDKAPE--QKHQAQEQKDKVSEKKDQA--LEQKY 1555
Cdd:PRK02224 408 GNAEDFLEELREERD-ELREREAELEAtlRTARERVEE--AEALLEAGKCPEcgQPVEGSPHVETIEEDRERVeeLEAEL 484
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1556 WALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSpEKVKAMEEKLEALLEKTKALGlEESLVQEGRARE 1635
Cdd:PRK02224 485 EDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERR-ETIEEKRERAEELRERAAELE-AEAEEKREAAAE 562
|
330
....*....|....
gi 313104325 1636 QEEkywRGQDVVQE 1649
Cdd:PRK02224 563 AEE---EAEEAREE 573
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1349-1645 |
8.64e-06 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 50.67 E-value: 8.64e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1349 LKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVvepKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKA 1428
Cdd:COG4372 50 LREELEQAREELEQLEEELEQARSELEQLEE---ELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQD 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1429 LEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQkdrvleqkEKIPEEKDKALDQKVRSVEH 1508
Cdd:COG4372 127 LEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSE--------AEAEQALDELLKEANRNAEK 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1509 KAPedtvaemKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWalgqkdEALEQNIQALEENHQTQEQESLVQED 1588
Cdd:COG4372 199 EEE-------LAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALL------DALELEEDKEELLEEVILKEIEELEL 265
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 313104325 1589 KTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQD 1645
Cdd:COG4372 266 AILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALL 322
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
274-762 |
9.46e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 51.68 E-value: 9.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 274 NKILEGLEKLRHLDFLRYPVATQKDLASGAvpTNLKPSKIKQRADskESLKATTKTAVSKLAKREEVVE--EGAKEARSE 351
Cdd:PTZ00121 1251 NEEIRKFEEARMAHFARRQAAIKAEEARKA--DELKKAEEKKKAD--EAKKAEEKKKADEAKKKAEEAKkaDEAKKKAEE 1326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 352 LAKELAKTEKKAKESSEKPPEKPAKPERVKTEsseaLKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELK 431
Cdd:PTZ00121 1327 AKKKADAAKKKAEEAKKAAEAAKAEAEAAADE----AEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEE 1402
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 432 KDEGRKEEKKDAKKEEKRKDTKPELKKISKPD-LKPFTPEVRKT-LYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQK 509
Cdd:PTZ00121 1403 DKKKADELKKAAAAKKKADEAKKKAEEKKKADeAKKKAEEAKKAdEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEA 1482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 510 GTVplPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRdtglgDKPFPLDTAEEGPPSTAIQGTPP--SVPGLGQEE 587
Cdd:PTZ00121 1483 KKA--DEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEA-----KKADEAKKAEEAKKADEAKKAEEkkKADELKKAE 1555
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 588 HVMK--EKELVPEVPEEQGSKDRGLDSGAETE--EEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEEMEE 663
Cdd:PTZ00121 1556 ELKKaeEKKKAEEAKKAEEDKNMALRKAEEAKkaEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKV 1635
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 664 VHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLSSLTTPAGATEHVSYIQDEtipgy 743
Cdd:PTZ00121 1636 EQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKK----- 1710
|
490
....*....|....*....
gi 313104325 744 sETEQTISDEEIHDEPEER 762
Cdd:PTZ00121 1711 -EAEEKKKAEELKKAEEEN 1728
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
1435-1611 |
1.10e-05 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 50.98 E-value: 1.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1435 DLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKdrvLEQK-EKIPEEKDKALDQKVRSVEHKAPED 1513
Cdd:PRK00409 524 SLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEE---AEKEaQQAIKEAKKEADEIIKELRQLQKGG 600
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1514 TvAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQAL----EQKYWALGQKDEALEqniqaLEENHQTQEQESL----V 1585
Cdd:PRK00409 601 Y-ASVKAHELIEARKRLNKANEKKEKKKKKQKEKQEELkvgdEVKYLSLGQKGEVLS-----IPDDKEAIVQAGImkmkV 674
|
170 180
....*....|....*....|....*.
gi 313104325 1586 QEDKTRKPKMLEEKSPEKVKAMEEKL 1611
Cdd:PRK00409 675 PLSDLEKIQKPKKKKKKKPKTVKPKP 700
|
|
| GBP_C |
cd16269 |
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ... |
1364-1488 |
1.25e-05 |
|
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.
Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 49.88 E-value: 1.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1364 DEVLQQKdktLEHKEVVEpkdTAIYQKDEAL----------HVKNEAVKQQDKALEQKGRDLEQKdtaLEQKDKALEPKD 1433
Cdd:cd16269 169 EEVLQEF---LQSKEAEA---EAILQADQALtekekeieaeRAKAEAAEQERKLLEEQQRELEQK---LEDQERSYEEHL 239
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 313104325 1434 KDLEEKDKalEQKDKIPEEKDKALEQKdtaLEQKDKALEpkdKDLEQKDRVLEQK 1488
Cdd:cd16269 240 RQLKEKME--EERENLLKEQERALESK---LKEQEALLE---EGFKEQAELLQEE 286
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1343-1668 |
1.36e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.83 E-value: 1.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1343 EDKVPGLKDRTSEQKKEpepkDEVLQQKDKTLEH-KEVVEPKDTAIYQKDEALHVKNEAVK------QQDKALEQKGRDL 1415
Cdd:PRK03918 258 EEKIRELEERIEELKKE----IEELEEKVKELKElKEKAEEYIKLSEFYEEYLDELREIEKrlsrleEEINGIEERIKEL 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1416 EQKDTALEQ---KDKALEPKDKDLEEKDKALE------------QKDKIPEEKDKaLEQKDTALEQKDKALEPKDKDLEQ 1480
Cdd:PRK03918 334 EEKEERLEElkkKLKELEKRLEELEERHELYEeakakkeelerlKKRLTGLTPEK-LEKELEELEKAKEEIEEEISKITA 412
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1481 KDRVLEQKEKipeEKDKALdQKVRSVEHKAP---------------EDTVAEMKdRDLEQTDKAPEQKHQAQEQKDKV-- 1543
Cdd:PRK03918 413 RIGELKKEIK---ELKKAI-EELKKAKGKCPvcgrelteehrkellEEYTAELK-RIEKELKEIEEKERKLRKELRELek 487
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1544 ---SEKKDQALEQKYWALGQKDEALEQ-NIQALEENHQTQEQ----------ESLVQEDKTRKPKMLEEKSPE---KVKA 1606
Cdd:PRK03918 488 vlkKESELIKLKELAEQLKELEEKLKKyNLEELEKKAEEYEKlkekliklkgEIKSLKKELEKLEELKKKLAElekKLDE 567
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 313104325 1607 MEEKLEALLEKTKALGLEESLVQEGRAREQEEKYwrgqdvvQEWQETSPTREEPAGEQKELA 1668
Cdd:PRK03918 568 LEEELAELLKELEELGFESVEELEERLKELEPFY-------NEYLELKDAEKELEREEKELK 622
|
|
| PRK00106 |
PRK00106 |
ribonuclease Y; |
1394-1553 |
1.39e-05 |
|
ribonuclease Y;
Pssm-ID: 178867 [Multi-domain] Cd Length: 535 Bit Score: 50.64 E-value: 1.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1394 LHVKNEAVKQQDKAleqkGRDLEQKDTALEQKDKALEpKDKDLEEKDKALEQKDKIPEE---KDKALEQKDTALEQKDKA 1470
Cdd:PRK00106 38 LNAEQEAVNLRGKA----ERDAEHIKKTAKRESKALK-KELLLEAKEEARKYREEIEQEfksERQELKQIESRLTERATS 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1471 LEPKDKDLEQKDRVLEQKEKIPEEKDKALD---QKVRSVEHKAPED-------TVAEMKDRDLEQTDK------APEQKH 1534
Cdd:PRK00106 113 LDRKDENLSSKEKTLESKEQSLTDKSKHIDereEQVEKLEEQKKAElervaalSQAEAREIILAETENkltheiATRIRE 192
|
170
....*....|....*....
gi 313104325 1535 QAQEQKDKVSEKKDQALEQ 1553
Cdd:PRK00106 193 AEREVKDRSDKMAKDLLAQ 211
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
1365-1659 |
1.41e-05 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 50.88 E-value: 1.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1365 EVLQQKDKTLEHKEVVEPKDTAIyqkdEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALE 1444
Cdd:pfam05483 100 ELKQKENKLQENRKIIEAQRKAI----QELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYE 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1445 ----QKDKIPEEKDKALEQKDTALEQKdkALEPKDKDLEQKDRVLEQKEKI---PEEKDKALDQKVRSVEHKAPEDTVAE 1517
Cdd:pfam05483 176 yereETRQVYMDLNNNIEKMILAFEEL--RVQAENARLEMHFKLKEDHEKIqhlEEEYKKEINDKEKQVSLLLIQITEKE 253
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1518 MKDRDLeqtdkapeqKHQAQEQKDKVSEkkdqaLEQKywaLGQKDEALEQNIQalEENHQTQEQESLvqedktrkpKMLE 1597
Cdd:pfam05483 254 NKMKDL---------TFLLEESRDKANQ-----LEEK---TKLQDENLKELIE--KKDHLTKELEDI---------KMSL 305
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 313104325 1598 EKSPEKVKAMEEKLEAlleKTKALgleESLVQEGRAREQEEKYWRGQD--VVQEWQETSPTREE 1659
Cdd:pfam05483 306 QRSMSTQKALEEDLQI---ATKTI---CQLTEEKEAQMEELNKAKAAHsfVVTEFEATTCSLEE 363
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1413-1612 |
1.52e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.83 E-value: 1.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1413 RDLEQKDTALEQKDKALEPKDKDLEEKDKALEQK--------DKIPE------------EKDKALEQKDTALEQKDKALE 1472
Cdd:PRK03918 172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVlreineisSELPElreeleklekevKELEELKEEIEELEKELESLE 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1473 PKDKDLEQKDRVLEQKEKIPEEKDKALDQKVR---SVEHKAPE-DTVAEMKD------RDLEQTDKAPEQKHQA-QEQKD 1541
Cdd:PRK03918 252 GSKRKLEEKIRELEERIEELKKEIEELEEKVKelkELKEKAEEyIKLSEFYEeyldelREIEKRLSRLEEEINGiEERIK 331
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 313104325 1542 KVSEKKDQALEqkywaLGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLE 1612
Cdd:PRK03918 332 ELEEKEERLEE-----LKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELE 397
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1977-2213 |
1.57e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 50.94 E-value: 1.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1977 TGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPK--SLQSDTPTFSYAALAGPTVPPRPEPGpsME 2054
Cdd:PHA03307 200 AAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCgwGPENECPLPRPAPITLPTRIWEASGW--NG 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2055 PSLTPPAVPPRAPILSKGPSPPlngnilSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMG 2134
Cdd:PHA03307 278 PSSRPGPASSSSSPRERSPSPS------PSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSP 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2135 SPtlwPETEAHVSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSA----PCGSLAFSGDRALALAPGPPT 2210
Cdd:PHA03307 352 SP---SRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDAtgrfPAGRPRPSPLDAGAASGAFYA 428
|
...
gi 313104325 2211 RTR 2213
Cdd:PHA03307 429 RYP 431
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
2030-2267 |
1.74e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 50.26 E-value: 1.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2030 TPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGnilscsPDRRSPSPkesgrshwddstsdsE 2109
Cdd:PRK12323 373 GPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAA------PARRSPAP---------------E 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2110 LEKGAREQPEKEAQSPSPPHPIPMGSPTlwpeteAHVSPPLDSHLGPARPSLDFPASAfgfsslQPAPPQLPSPAEPRSA 2189
Cdd:PRK12323 432 ALAAARQASARGPGGAPAPAPAPAAAPA------AAARPAAAGPRPVAAAAAAAPARA------APAAAPAPADDDPPPW 499
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 313104325 2190 PCGSLAFSGDRALALAPGPPTRTRHDEYLEVTKAPSlDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPV 2267
Cdd:PRK12323 500 EELPPEFASPAPAQPDAAPAGWVAESIPDPATADPD-DAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDM 576
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
1368-1652 |
1.88e-05 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 49.53 E-value: 1.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1368 QQKDKTLEHKEvvepkDTAIYQKDEALHVKNEAvKQQDKALEQKGRDLEQKDTALEQ----KDKALEPKDKDLEEKDKAL 1443
Cdd:pfam13868 31 KKRIKAEEKEE-----ERRLDEMMEEERERALE-EEEEKEEERKEERKRYRQELEEQieerEQKRQEEYEEKLQEREQMD 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1444 EQKDKIPEEKDKALEQKdtaLEQKDKALEPKDKDLEQKDRvLEQKEKipeEKDKALDQKV---------RSVEHKAPEDT 1514
Cdd:pfam13868 105 EIVERIQEEDQAEAEEK---LEKQRQLREEIDEFNEEQAE-WKELEK---EEEREEDERIleylkekaeREEEREAEREE 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1515 VAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEAlEQNIQALEENHQTQEQESL---------V 1585
Cdd:pfam13868 178 IEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEA-EKKARQRQELQQAREEQIElkerrlaeeA 256
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 313104325 1586 QEDKTRKPKMLeekspEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRG-QDVVQEWQE 1652
Cdd:pfam13868 257 EREEEEFERML-----RKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAErEEELEEGER 319
|
|
| PRK15374 |
PRK15374 |
type III secretion system needle tip complex protein SipB; |
1393-1592 |
1.88e-05 |
|
type III secretion system needle tip complex protein SipB;
Pssm-ID: 185272 [Multi-domain] Cd Length: 593 Bit Score: 50.35 E-value: 1.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1393 ALHVKNEAVKQQDKALEQKGRDLEQK-DTALEQKDKALEPKDKDLEEKDKAleqkdkipEEKDKALEQKDTALEQKDKAL 1471
Cdd:PRK15374 103 QLESRLAVWQAMIESQKEMGIQVSKEfQTALGEAQEATDLYEASIKKTDTA--------KSVYDAAEKKLTQAQNKLQSL 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1472 EPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVeHKAPEDTVAEMKDRD-----LEQTDKAPEQKHQAQEQKDKVSE- 1545
Cdd:PRK15374 175 DPADPGYAQAEAAVEQAGKEATEAKEALDKATDAT-VKAGTDAKAKAEKADniltkFQGTANAASQNQVSQGEQDNLSNv 253
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 313104325 1546 -KKDQALEQKYWALGQKDEALEQN----IQALEENHQTQ-EQESLVQEDKTRK 1592
Cdd:PRK15374 254 aRLTMLMAMFIEIVGKNTEESLQNdlalFNALQEGRQAEmEKKSAEFQEETRK 306
|
|
| tolA_full |
TIGR02794 |
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ... |
1321-1572 |
2.52e-05 |
|
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 49.07 E-value: 2.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1321 SSFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKdtaiyQKDEALHVKNEA 1400
Cdd:TIGR02794 21 GSLYHSVKPEPGGGAEIIQAVLVDPGAVAQQANRIQQQKKPAAKKEQERQKKLEQQAEEAEKQ-----RAAEQARQKELE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1401 VKQQDKALEQKGRdlEQKDTALEQKDKALEPKDKDLEEKDKALEQ---KDKIPEEKDKALEQ--KDTALEQKDKALEPKD 1475
Cdd:TIGR02794 96 QRAAAEKAAKQAE--QAAKQAEEKQKQAEEAKAKQAAEAKAKAEAeaeRKAKEEAAKQAEEEakAKAAAEAKKKAEEAKK 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1476 K-DLEQKDRVL-EQKEKIPEEKDKALDQKVRS-VEHKAPEDTVAEMKDRdleqtdKAPEQKHQAQEQKDKVSEKKDQALE 1552
Cdd:TIGR02794 174 KaEAEAKAKAEaEAKAKAEEAKAKAEAAKAKAaAEAAAKAEAEAAAAAA------AEAERKADEAELGDIFGLASGSNAE 247
|
250 260
....*....|....*....|
gi 313104325 1553 QKYWALGQKDEALEQNIQAL 1572
Cdd:TIGR02794 248 KQGGARGAAAGSEVDKYAAI 267
|
|
| tolA |
PRK09510 |
cell envelope integrity inner membrane protein TolA; Provisional |
1393-1567 |
2.74e-05 |
|
cell envelope integrity inner membrane protein TolA; Provisional
Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 49.42 E-value: 2.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1393 ALHVKNEAVKQQDKALEQKGRDleQKDtALEQKDKALEPKDKDLEEKDKALEQKDK-IPEEKDKALEQKDTALEQKDKAL 1471
Cdd:PRK09510 52 AVMVDPGAVVEQYNRQQQQQKS--AKR-AEEQRKKKEQQQAEELQQKQAAEQERLKqLEKERLAAQEQKKQAEEAAKQAA 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1472 EPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQ-----EQKDKVSEK 1546
Cdd:PRK09510 129 LKQKQAEEAAAKAAAAAKAKAEAEAKRAAAAAKKAAAEAKKKAEAEAAKKAAAEAKKKAEAEAAAKaaaeaKKKAEAEAK 208
|
170 180
....*....|....*....|.
gi 313104325 1547 KDQALEQKYWALGQKDEALEQ 1567
Cdd:PRK09510 209 KKAAAEAKKKAAAEAKAAAAK 229
|
|
| GBP_C |
pfam02841 |
Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral ... |
1364-1472 |
3.02e-05 |
|
Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral guanylate-binding protein (GBP) is induced by interferon-gamma during macrophage induction. This family contains GBP1 and GPB2, both GTPases capable of binding GTP, GDP and GMP.
Pssm-ID: 460721 [Multi-domain] Cd Length: 297 Bit Score: 48.44 E-value: 3.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1364 DEVLQQkdkTLEHKEVVEpkdTAIYQKDEAL----------HVKNEAVKQQDKALEQKGRDLEQKdtaLEQKDKALEPKD 1433
Cdd:pfam02841 175 EEVLQE---FLQSKEAVE---EAILQTDQALtakekaieaeRAKAEAAEAEQELLREKQKEEEQM---MEAQERSYQEHV 245
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 313104325 1434 KDLEEKdkaLEQ-KDKIPEEKDKALEQKdtALEQKDKALE 1472
Cdd:pfam02841 246 KQLIEK---MEAeREQLLAEQERMLEHK--LQEQEELLKE 280
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1350-1667 |
3.04e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.77 E-value: 3.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1350 KDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPkdtaIYQKDEALhvkneavKQQDKALEQKGRDLEQKDTALEQKDKAL 1429
Cdd:COG4717 97 LEELEEELEELEAELEELREELEKLEKLLQLLP----LYQELEAL-------EAELAELPERLEELEERLEELRELEEEL 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1430 EPKDKDLEEKDKALEqkdkipEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHK 1509
Cdd:COG4717 166 EELEAELAELQEELE------ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAA 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1510 APEDTVAEMK---------------------------------------------------DRDLEQTDKAPEQKHQAQE 1538
Cdd:COG4717 240 ALEERLKEARlllliaaallallglggsllsliltiagvlflvlgllallflllarekaslGKEAEELQALPALEELEEE 319
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1539 QKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKpKMLEEKSPEKVKAMEEKLEALLEKT 1618
Cdd:COG4717 320 ELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIA-ALLAEAGVEDEEELRAALEQAEEYQ 398
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 313104325 1619 KALG----LEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKEL 1667
Cdd:COG4717 399 ELKEeleeLEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEEL 451
|
|
| GBP_C |
cd16269 |
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ... |
1434-1614 |
3.37e-05 |
|
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.
Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 48.34 E-value: 3.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1434 KDLEEKdkALEQKDKIPEEKDKALEQK-DTALEQKDKALEPKDKD------------LEQKDRVLEQKEKIPEEKDKA-- 1498
Cdd:cd16269 93 KKLMEQ--LEEKKEEFCKQNEEASSKRcQALLQELSAPLEEKISQgsysvpggyqlyLEDREKLVEKYRQVPRKGVKAee 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1499 -LDQKVRSVEHKApedtvaemkdRDLEQTDKA---PEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEA----LEQNIQ 1570
Cdd:cd16269 171 vLQEFLQSKEAEA----------EAILQADQAlteKEKEIEAERAKAEAAEQERKLLEEQQRELEQKLEDqersYEEHLR 240
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 313104325 1571 ALEE------NHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEAL 1614
Cdd:cd16269 241 QLKEkmeeerENLLKEQERALESKLKEQEALLEEGFKEQAELLQEEIRSL 290
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
2122-2461 |
4.07e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 49.46 E-value: 4.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2122 AQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEprsapcgslafSGDRA 2201
Cdd:PRK07003 371 GVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPA-----------TADRG 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2202 LALAPGPPTRTRHDEylevtkAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFS-PSLE 2280
Cdd:PRK07003 440 DDAADGDAPVPAKAN------ARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPdARAP 513
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2281 AAEQESGELDPGMEPAAHSLwDLTPLSPAPP-------ASLDLALAPAPSLPGDMGDgilpchlecSEAATEKPSPFQVP 2353
Cdd:PRK07003 514 AAASREDAPAAAAPPAPEAR-PPTPAAAAPAaraggaaAALDVLRNAGMRVSSDRGA---------RAAAAAKPAAAPAA 583
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2354 SEDCAANGPTETSPNPPGPAPAKAENEEAAAcpaweRGAWPEGAERSSRPDTLLSPEQ--PVCPAGGSGGPPSSASPEVE 2431
Cdd:PRK07003 584 APKPAAPRVAVQVPTPRARAATGDAPPNGAA-----RAEQAAESRGAPPPWEDIPPDDyvPLSADEGFGGPDDGFVPVFD 658
|
330 340 350
....*....|....*....|....*....|
gi 313104325 2432 AGPQGCATEPRPHRGElSPSFLNPPLPPSI 2461
Cdd:PRK07003 659 SGPDDVRVAPKPADAP-APPVDTRPLPPAI 687
|
|
| PRK05901 |
PRK05901 |
RNA polymerase sigma factor; Provisional |
1318-1529 |
4.22e-05 |
|
RNA polymerase sigma factor; Provisional
Pssm-ID: 235640 [Multi-domain] Cd Length: 509 Bit Score: 48.84 E-value: 4.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1318 TPDSSFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSEQKKEPepKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVK 1397
Cdd:PRK05901 3 TASTKAELAAEEEAKKKLKKLAAKSKSKGFITKEEIKEALESK--KKTPEQIDQVLIFLSGMVKDTDDATESDIPKKKTK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1398 NEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKD 1477
Cdd:PRK05901 81 TAAKAAAAKAPAKKKLKDELDSSKKAEKKNALDKDDDLNYVKDIDVLNQADDDDDDDDDDDLDDDDIDDDDDDEDDDEDD 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 313104325 1478 LEQKDRVLEQKEKIPEEKDKALDQKvrSVEHKAPEDTVAEMKDRDLEQTDKA 1529
Cdd:PRK05901 161 DDDDVDDEDEEKKEAKELEKLSDDD--DFVWDEDDSEALRQARKDAKLTATA 210
|
|
| tolA |
PRK09510 |
cell envelope integrity inner membrane protein TolA; Provisional |
1367-1564 |
5.03e-05 |
|
cell envelope integrity inner membrane protein TolA; Provisional
Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 48.26 E-value: 5.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1367 LQQKDKTLEHKEVVEPKDTAiyQKDEALHVKNEAVKQQDKALEQkgrdleQKDTALEQKDKALEPKDKDLEEKDKALEQK 1446
Cdd:PRK09510 67 QQQQQKSAKRAEEQRKKKEQ--QQAEELQQKQAAEQERLKQLEK------ERLAAQEQKKQAEEAAKQAALKQKQAEEAA 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1447 DKIPEE-KDKALEQKDTALEQKDKALEPKDKdLEQKDRVLEQKEKIPEEKDKALDQKVRSvEHKAPEDTVAEMKDRDLEQ 1525
Cdd:PRK09510 139 AKAAAAaKAKAEAEAKRAAAAAKKAAAEAKK-KAEAEAAKKAAAEAKKKAEAEAAAKAAA-EAKKKAEAEAKKKAAAEAK 216
|
170 180 190
....*....|....*....|....*....|....*....
gi 313104325 1526 TDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEA 1564
Cdd:PRK09510 217 KKAAAEAKAAAAKAAAEAKAAAEKAAAAKAAEKAAAAKA 255
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
1363-1634 |
5.24e-05 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 47.99 E-value: 5.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1363 KDEVLQQKDKTLEHKEVVEPKDTAIYQKDEalhvkNEAVKQQDKALEQKGRD-LEQKDTALEQKDKA-----LEPKDKDL 1436
Cdd:pfam13868 55 RALEEEEEKEEERKEERKRYRQELEEQIEE-----REQKRQEEYEEKLQEREqMDEIVERIQEEDQAeaeekLEKQRQLR 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1437 EEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRvlEQKEKIPEEKDKALDQKVRSVEHKAPEDTV- 1515
Cdd:pfam13868 130 EEIDEFNEEQAEWKELEKEEEREEDERILEYLKEKAEREEEREAERE--EIEEEKEREIARLRAQQEKAQDEKAERDELr 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1516 ----AEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALgQKDEALEQNIQALEENHQTQEQESLVQEDKTR 1591
Cdd:pfam13868 208 aklyQEEQERKERQKEREEAEKKARQRQELQQAREEQIELKERRLAE-EAEREEEEFERMLRKQAEDEEIEQEEAEKRRM 286
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 313104325 1592 K--------PKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAR 1634
Cdd:pfam13868 287 KrlehrrelEKQIEEREEQRAAEREEELEEGERLREEEAERRERIEEERQK 337
|
|
| Borrelia_P83 |
pfam05262 |
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins. |
1426-1613 |
5.76e-05 |
|
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
Pssm-ID: 114011 [Multi-domain] Cd Length: 489 Bit Score: 48.46 E-value: 5.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1426 DKALEPKDKDLEEKDKALEQKDKipeEKDKALEQKDTALEQKDKALEPKDKDLEQKDRvleqkekipeeKDKALDQKVRS 1505
Cdd:pfam05262 184 EALREDNEKGVNFRRDMTDLKER---ESQEDAKRAQQLKEELDKKQIDADKAQQKADF-----------AQDNADKQRDE 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1506 VEHKAPEDTVAEMKDRdleqTDKAPEQKHQAQEQKdKVSEKKDQALEQK-YWALGQKDEALEQNIQALEENHQTQEQESL 1584
Cdd:pfam05262 250 VRQKQQEAKNLPKPAD----TSSPKEDKQVAENQK-REIEKAQIEIKKNdEEALKAKDHKAFDLKQESKASEKEAEDKEL 324
|
170 180 190
....*....|....*....|....*....|....*
gi 313104325 1585 vQEDKTRKP------KMLEEKSPEKVKAMEEKLEA 1613
Cdd:pfam05262 325 -EAQKKREPvaedlqKTKPQVEAQPTSLNEDAIDS 358
|
|
| tolA_full |
TIGR02794 |
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ... |
1380-1594 |
7.26e-05 |
|
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 47.92 E-value: 7.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1380 VEPKDTAIYQKDEALHVKNEAVKQQDKALEQkgrdlEQKDTAleqkdKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQ 1459
Cdd:TIGR02794 27 VKPEPGGGAEIIQAVLVDPGAVAQQANRIQQ-----QKKPAA-----KKEQERQKKLEQQAEEAEKQRAAEQARQKELEQ 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1460 KDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVrsvEHKAPEDtvAEMKDRDLEQTDKAPEQKHQAQEQ 1539
Cdd:TIGR02794 97 RAAAEKAAKQAEQAAKQAEEKQKQAEEAKAKQAAEAKAKAEAEA---ERKAKEE--AAKQAEEEAKAKAAAEAKKKAEEA 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 313104325 1540 KDKV-SEKKDQAL-EQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPK 1594
Cdd:TIGR02794 172 KKKAeAEAKAKAEaEAKAKAEEAKAKAEAAKAKAAAEAAAKAEAEAAAAAAAEAERK 228
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
1399-1671 |
7.52e-05 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 48.41 E-value: 7.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1399 EAVKQQDKALEQkgrDLEQKD-------TALEQKDKaLEPKDKDLEEKDKALEQKDKIPEEKDkalEQKDTALEQKDKAL 1471
Cdd:PRK04863 317 AELNEAESDLEQ---DYQAASdhlnlvqTALRQQEK-IERYQADLEELEERLEEQNEVVEEAD---EQQEENEARAEAAE 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1472 EPKDK------DLEQKDRVLeQKEKIPEEKDKALDQKVRSVEHKAP------EDTVAEMKDRDLEQTDKAPEQKHQ---- 1535
Cdd:PRK04863 390 EEVDElksqlaDYQQALDVQ-QTRAIQYQQAVQALERAKQLCGLPDltadnaEDWLEEFQAKEQEATEELLSLEQKlsva 468
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1536 --AQEQKDKV-------------SEKKDQALE-----QKYWALGQKDEALEQNIQALEENHQTQ-EQESLVQEDKTRKPK 1594
Cdd:PRK04863 469 qaAHSQFEQAyqlvrkiagevsrSEAWDVAREllrrlREQRHLAEQLQQLRMRLSELEQRLRQQqRAERLLAEFCKRLGK 548
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 313104325 1595 MLEekSPEKVKAMEEKLEALLEktkalGLEESLVQEGRAREQEEkywrgqdvvQEWQETSPTREEPAgeqkELAPAW 1671
Cdd:PRK04863 549 NLD--DEDELEQLQEELEARLE-----SLSESVSEARERRMALR---------QQLEQLQARIQRLA----ARAPAW 605
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
2036-2327 |
9.50e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 48.06 E-value: 9.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2036 AALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRsPSPKESGRSHWDDSTSDSELEKGAR 2115
Cdd:PRK07764 412 PAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQ-PAPAPAAAPEPTAAPAPAPPAAPAP 490
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2116 EQPEKEAQSPSPPHPiPMGSPTL---WPE-----------------TEAHVSPPLDSHL--------------------- 2154
Cdd:PRK07764 491 AAAPAAPAAPAAPAG-ADDAATLrerWPEilaavpkrsrktwaillPEATVLGVRGDTLvlgfstgglarrfaspgnaev 569
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2155 -------------------GPARPSLDFPASAFGFSSL----QPAPPQLPSPAEP-RSAPCGSLAFSGDRALALAPGPPT 2210
Cdd:PRK07764 570 lvtalaeelggdwqveavvGPAPGAAGGEGPPAPASSGppeeAARPAAPAAPAAPaAPAPAGAAAAPAEASAAPAPGVAA 649
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2211 RTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPSLEAAEQESGeld 2290
Cdd:PRK07764 650 PEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQ--- 726
|
330 340 350
....*....|....*....|....*....|....*..
gi 313104325 2291 pGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGD 2327
Cdd:PRK07764 727 -GASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPP 762
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
1256-1626 |
1.03e-04 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 47.97 E-value: 1.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1256 PEPHAATASPPTDGTTRYSAQTDITDDSLDRKSPASSFSHSTPSGNGKYLP--------GAITSPDEHILTPDSSFSKsp 1327
Cdd:PLN02939 76 ENTSLRTVMELPQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSKDGEQLSdfqledlvGMIQNAEKNILLLNQARLQ-- 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1328 eslpgpALEDIaikweDKVpgLKDRtseqkkepepkdEVLQQKDKTLEHKevvepkdtaIYQKDEALHVKNEA---VKQQ 1404
Cdd:PLN02939 154 ------ALEDL-----EKI--LTEK------------EALQGKINILEMR---------LSETDARIKLAAQEkihVEIL 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1405 DKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALeqKDKIPEEKDKALEQKDT-----ALEQKDKALEPKDKDLE 1479
Cdd:PLN02939 200 EEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLL--KDDIQFLKAELIEVAETeervfKLEKERSLLDASLRELE 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1480 QKDRVL-EQKEKIPEEKDKALDQKVRSVEHkapedtvaeMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWAL 1558
Cdd:PLN02939 278 SKFIVAqEDVSKLSPLQYDCWWEKVENLQD---------LLDRATNQVEKAALVLDQNQDLRDKVDKLEASLKEANVSKF 348
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 313104325 1559 G-QKDEALEQNIQALEENHQTQEQESLVQEDktrkpkmLEEKSpekVKAMEEKLEALLEKTKALGLEES 1626
Cdd:PLN02939 349 SsYKVELLQQKLKLLEERLQASDHEIHSYIQ-------LYQES---IKEFQDTLSKLKEESKKRSLEHP 407
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1429-1652 |
1.15e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.99 E-value: 1.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1429 LEPKDkdLEEK-DKALEQKDKIpeekDKALEQKDTALEQKDkALEPKDKDLEQKDRVLEQKEKIpeekdKALDQKVRSVE 1507
Cdd:COG4913 218 LEEPD--TFEAaDALVEHFDDL----ERAHEALEDAREQIE-LLEPIRELAERYAAARERLAEL-----EYLRAALRLWF 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1508 HKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQaLEQKYWALGQKD-EALEQNIQALEENHQTQEQESLVQ 1586
Cdd:COG4913 286 AQRRLELLEAELEELRAELARLEAELERLEARLDALREELDE-LEAQIRGNGGDRlEQLEREIERLERELEERERRRARL 364
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 313104325 1587 EDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKAlglEESLVQEgRAREQEEKYWRGQDVVQEWQE 1652
Cdd:COG4913 365 EALLAALGLPLPASAEEFAALRAEAAALLEALEE---ELEALEE-ALAEAEAALRDLRRELRELEA 426
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1398-1498 |
1.51e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.68 E-value: 1.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1398 NEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKD 1477
Cdd:COG4942 145 APARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
|
90 100
....*....|....*....|.
gi 313104325 1478 LEQKDRVLEQKEKIPEEKDKA 1498
Cdd:COG4942 225 LEALIARLEAEAAAAAERTPA 245
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
1925-2208 |
1.57e-04 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 47.37 E-value: 1.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1925 PDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTR------EPPLGAAGDWPP 1998
Cdd:PHA03378 576 PLTSPTTSQLASSAPSYAQTPWPVPHPSQTPEPPTTQSHIPETSAPRQWPMPLRPIPMRPLRmqpitfNVLVFPTPHQPP 655
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1999 clstKEAAAGRNTSAEKELSSPISPkslqsdTPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPP---RAPILSKGPSP 2075
Cdd:PHA03378 656 ----QVEITPYKPTWTQIGHIPYQP------SPTGANTMLPIQWAPGTMQPPPRAPTPMRPPAAPPgraQRPAAATGRAR 725
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2076 PLNGNILSCSPDRRSPSPKESGRShwDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLG 2155
Cdd:PHA03378 726 PPAAAPGRARPPAAAPGRARPPAA--APGRARPPAAAPGRARPPAAAPGAPTPQPPPQAPPAPQQRPRGAPTPQPPPQAG 803
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 313104325 2156 PARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPGP 2208
Cdd:PHA03378 804 PTSMQLMPRAAPGQQGPTKQILRQLLTGGVKRGRPSLKKPAALERQAAAGPTP 856
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1365-1576 |
1.62e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.60 E-value: 1.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1365 EVLQQ-KDKTLEHKEVVEPKDTAIYQKDEALHVKNEavkQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKAL 1443
Cdd:COG4913 252 ELLEPiRELAERYAAARERLAELEYLRAALRLWFAQ---RRLELLEAELEELRAELARLEAELERLEARLDALREELDEL 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1444 EQkdKIPEEKDKALEQkdtaLEQKDKALEpkdKDLEQKDRVLEQkekipeekdkaLDQKVRSVEHKAP--EDTVAEMKDR 1521
Cdd:COG4913 329 EA--QIRGNGGDRLEQ----LEREIERLE---RELEERERRRAR-----------LEALLAALGLPLPasAEEFAALRAE 388
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 313104325 1522 DLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKywalgqkdEALEQNIQALEENH 1576
Cdd:COG4913 389 AAALLEALEEELEALEEALAEAEAALRDLRREL--------RELEAEIASLERRK 435
|
|
| DUF4659 |
pfam15558 |
Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins ... |
1390-1658 |
1.66e-04 |
|
Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins in this family are typically between 427 and 674 amino acids in length. There are two completely conserved residues (D and I) that may be functionally important.
Pssm-ID: 464768 [Multi-domain] Cd Length: 374 Bit Score: 46.57 E-value: 1.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1390 KDEALHVKNEAVKQQD--KALEQKGRDLEQKDTAL--EQKDKALEPKDKDLEEKDKALEQkdkiPEEKDKALEQKdtaLE 1465
Cdd:pfam15558 40 RDQKRQETLERERRLLlqQSQEQWQAEKEQRKARLgrEERRRADRREKQVIEKESRWREQ----AEDQENQRQEK---LE 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1466 QKdkALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKD-RDLEQTDKAPEQKHQAQEQKDKVS 1544
Cdd:pfam15558 113 RA--RQEAEQRKQCQEQRLKEKEEELQALREQNSLQLQERLEEACHKRQLKEREEqKKVQENNLSELLNHQARKVLVDCQ 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1545 EKKDQALEQKywalgqkdeALEQNIQALEENHQTQEQESLvQEDKTRKPKmlEEKSPEKVK-AMEEKLEALLEKTKALGL 1623
Cdd:pfam15558 191 AKAEELLRRL---------SLEQSLQRSQENYEQLVEERH-RELREKAQK--EEEQFQRAKwRAEEKEEERQEHKEALAE 258
|
250 260 270
....*....|....*....|....*....|....*
gi 313104325 1624 EESLVQEgRAREQEEKywRGQDVVQEWQETSPTRE 1658
Cdd:pfam15558 259 LADRKIQ-QARQVAHK--TVQDKAQRARELNLERE 290
|
|
| tolA |
PRK09510 |
cell envelope integrity inner membrane protein TolA; Provisional |
1466-1639 |
2.14e-04 |
|
cell envelope integrity inner membrane protein TolA; Provisional
Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 46.34 E-value: 2.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1466 QKDKALEPKDKDlEQKDRVLEQKEKIPEEKDKALDQKVRSVEhkapedtvaemKDRDLEQtdkapEQKHQAQEQKDKVSE 1545
Cdd:PRK09510 67 QQQQQKSAKRAE-EQRKKKEQQQAEELQQKQAAEQERLKQLE-----------KERLAAQ-----EQKKQAEEAAKQAAL 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1546 KKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKtKAlgleE 1625
Cdd:PRK09510 130 KQKQAEEAAAKAAAAAKAKAEAEAKRAAAAAKKAAAEAKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKK-KA----E 204
|
170
....*....|....
gi 313104325 1626 SLVQEGRAREQEEK 1639
Cdd:PRK09510 205 AEAKKKAAAEAKKK 218
|
|
| DUF4686 |
pfam15742 |
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ... |
1343-1598 |
2.30e-04 |
|
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.
Pssm-ID: 464838 [Multi-domain] Cd Length: 384 Bit Score: 46.21 E-value: 2.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1343 EDKVPGLKDRTSE-QKKEPEpkdevLQQKdktLEHKEVVEPKDTAIYQKD-------EALhvKNEA-VKQQDKALEQKGR 1413
Cdd:pfam15742 113 QEKLAQEKSRVADaEEKILE-----LQQK---LEHAHKVCLTDTCILEKKqleerikEAS--ENEAkLKQQYQEEQQKRK 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1414 DLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKAlepkDKDLEQKDRVLEQ-KEKIP 1492
Cdd:pfam15742 183 LLDQNVNELQQQVRSLQDKEAQLEMTNSQQQLRIQQQEAQLKQLENEKRKSDEHLKS----NQELSEKLSSLQQeKEALQ 258
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1493 EEKDKAL---DQKVRS-----VEHKAPEDTVAEMKDRDLEQTDKAPEQ-KHQ---AQEQKDKVSEKKDQALEQKYWALGQ 1560
Cdd:pfam15742 259 EELQQVLkqlDVHVRKynekhHHHKAKLRRAKDRLVHEVEQRDERIKQlENEigiLQQQSEKEKAFQKQVTAQNEILLLE 338
|
250 260 270
....*....|....*....|....*....|....*...
gi 313104325 1561 KDEALEQNIQALEENHQTQEQESLVQedktRKPKMLEE 1598
Cdd:pfam15742 339 KRKLLEQLTEQEELIKNNKRTISSVQ----NRVNFLDE 372
|
|
| GAS |
pfam13851 |
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
1335-1487 |
2.36e-04 |
|
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.
Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 44.90 E-value: 2.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1335 LEDIAiKWEDKVPGLKDRTSEQKKEpepKDEVLQQKD---KTLEH--KEVVE-PKDTAIYQKD-EALhvknEAVKQQDKA 1407
Cdd:pfam13851 25 LELIK-SLKEEIAELKKKEERNEKL---MSEIQQENKrltEPLQKaqEEVEElRKQLENYEKDkQSL----KNLKARLKV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1408 LEQKGRDLEQKDTALEQKDKALEpkdkdlEEKDKALE-QKDKIPEEKDKAlEQKDTALEQKDKALepkDKDLEQKDRVLE 1486
Cdd:pfam13851 97 LEKELKDLKWEHEVLEQRFEKVE------RERDELYDkFEAAIQDVQQKT-GLKNLLLEKKLQAL---GETLEKKEAQLN 166
|
.
gi 313104325 1487 Q 1487
Cdd:pfam13851 167 E 167
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1414-1667 |
2.62e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 46.60 E-value: 2.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1414 DLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPE 1493
Cdd:PRK03918 159 DYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKE 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1494 EKDKaLDQKVRSVEHKAPEdtvAEMKDRDLEqtDKAPEQKHQAQEQKDKVSE-KKDQALEQKYWALGQKDEALEQNIQAL 1572
Cdd:PRK03918 239 EIEE-LEKELESLEGSKRK---LEEKIRELE--ERIEELKKEIEELEEKVKElKELKEKAEEYIKLSEFYEEYLDELREI 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1573 EENHQTQEQESLVQEdktRKPKMLEEKSpEKVKAMEEKLEALLE-----KTKALGLEESLVQEGRAR--EQEEKYWRGQD 1645
Cdd:PRK03918 313 EKRLSRLEEEINGIE---ERIKELEEKE-ERLEELKKKLKELEKrleelEERHELYEEAKAKKEELErlKKRLTGLTPEK 388
|
250 260
....*....|....*....|..
gi 313104325 1646 VVQEWQETSPTREEPAGEQKEL 1667
Cdd:PRK03918 389 LEKELEELEKAKEEIEEEISKI 410
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
2165-2462 |
2.96e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 46.70 E-value: 2.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2165 ASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAfSGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSS-PGAPL 2243
Cdd:PHA03307 14 AAEGGEFFPRPPATPGDAADDLLSGSQGQLV-SDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRStPTWSL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2244 LSNLPRPASPALSEGSSSEATTPVISSVAERFSPSLEAAEQESGELDPGME--PAAHSLWDLTPLSPAPPASlDLALAPA 2321
Cdd:PHA03307 93 STLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSpgPPPAASPPAAGASPAAVAS-DAASSRQ 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2322 PSLPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWERGAWPEGAERSS 2401
Cdd:PHA03307 172 AALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGP 251
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 313104325 2402 RPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSF-LNPPLPPSID 2462
Cdd:PHA03307 252 ENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSpGSGPAPSSPR 313
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
1365-1614 |
3.25e-04 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 46.75 E-value: 3.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1365 EVLQQKDKTL---EHKEVVEPKDTAIYQKDEALhvkNEAVKQQDKALEQKGRDLEQKDTALEQK---DKALEPKDKDLEE 1438
Cdd:PTZ00440 1008 NILNKKIDDLikkQHDDIIELIDKLIKEKGKEI---EEKVDQYISLLEKMKTKLSSFHFNIDIKkykNPKIKEEIKLLEE 1084
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1439 KDKAL-----EQKDKIPEEKDKALEQKDTALEQKDKALEP---KDKDLEqkdRVLEQKEKIPEEKDKALDQKVRSVEhka 1510
Cdd:PTZ00440 1085 KVEALlkkidENKNKLIEIKNKSHEHVVNADKEKNKQTEHynkKKKSLE---KIYKQMEKTLKELENMNLEDITLNE--- 1158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1511 pedtVAEMK--------DRDLEQ-TDKAPEQKHQAQE-----------QKDKVSEKKDQALEQKYWALGQKDEALEQNIQ 1570
Cdd:PTZ00440 1159 ----VNEIEieyeriliDHIVEQiNNEAKKSKTIMEEiesykkdidqvKKNMSKERNDHLTTFEYNAYYDKATASYENIE 1234
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 313104325 1571 ALEENHQTQEQESL----VQEDKTRKPKMLE--EKSPEKVKAMEEKLEAL 1614
Cdd:PTZ00440 1235 ELTTEAKGLKGEANrstnVDELKEIKLQVFSylQQVIKENNKMENALHEI 1284
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1335-1507 |
3.29e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 46.21 E-value: 3.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1335 LEDIAIKWEDKVPGLKDRTsEQKKEPEPKDEVLQQKDKTLEHK-------------EVVEPKDTAIyQKDEALHVKNEAV 1401
Cdd:PRK03918 530 LKEKLIKLKGEIKSLKKEL-EKLEELKKKLAELEKKLDELEEElaellkeleelgfESVEELEERL-KELEPFYNEYLEL 607
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1402 KQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKI-PEEKDKALEQKDTALEQKDKALEPKDKDLE- 1479
Cdd:PRK03918 608 KDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKySEEEYEELREEYLELSRELAGLRAELEELEk 687
|
170 180
....*....|....*....|....*...
gi 313104325 1480 QKDRVLEQKEKIPEEKDKaLDQKVRSVE 1507
Cdd:PRK03918 688 RREEIKKTLEKLKEELEE-REKAKKELE 714
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
1345-1625 |
3.34e-04 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 45.29 E-value: 3.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1345 KVPGLKDRTSEQKKEpepKDEVLQQ----KDKTLEHKEVVEpkdtAIYQKDEALhvkneavKQQDKALEQKGRDLEQKDT 1420
Cdd:COG1340 51 QVKELREEAQELREK---RDELNEKvkelKEERDELNEKLN----ELREELDEL-------RKELAELNKAGGSIDKLRK 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1421 ALEQKDKALEPKDKDLE-EKD--KALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDK 1497
Cdd:COG1340 117 EIERLEWRQQTEVLSPEeEKElvEKIKELEKELEKAKKALEKNEKLKELRAELKELRKEAEEIHKKIKELAEEAQELHEE 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1498 ALDQKvrsvehkapedtvaemKDRDlEQTDKAPEQKHQAQEQKDKVSEkkdqaLEQKYWALGQKDEALEQNIQALEEnhq 1577
Cdd:COG1340 197 MIELY----------------KEAD-ELRKEADELHKEIVEAQEKADE-----LHEEIIELQKELRELRKELKKLRK--- 251
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 313104325 1578 tqeqeslvQEDKTRKPKMLEEKSPEKVKAMEEklealLEKTKALGLEE 1625
Cdd:COG1340 252 --------KQRALKREKEKEELEEKAEEIFEK-----LKKGEKLTTEE 286
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
2176-2367 |
3.52e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 46.38 E-value: 3.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2176 APPQLPSPAEPRSAPCGSLAFSGDRALALAPGpptrtrhdeylevTKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPAL 2255
Cdd:PRK07003 367 APGGGVPARVAGAVPAPGARAAAAVGASAVPA-------------VTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPP 433
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2256 SEGSSSEATTPVISSVAerfSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPC 2335
Cdd:PRK07003 434 ATADRGDDAADGDAPVP---AKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDA 510
|
170 180 190
....*....|....*....|....*....|..
gi 313104325 2336 HLECSEAATEKPSPFQVPSEDCAANGPTETSP 2367
Cdd:PRK07003 511 RAPAAASREDAPAAAAPPAPEARPPTPAAAAP 542
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
1362-1621 |
3.66e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 46.37 E-value: 3.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1362 PKDEVLQQKDKTLE---------HKEVVEPK---DTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALeqkDKAL 1429
Cdd:pfam12128 241 PEFTKLQQEFNTLEsaelrlshlHFGYKSDEtliASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAA---DAAV 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1430 EPKDKDLEEKDKALEQKDKIPEEKDKA-LEQKDT------ALEQKDKALEPKDKDLEQKDRVLEQK---------EKIPE 1493
Cdd:pfam12128 318 AKDRSELEALEDQHGAFLDADIETAAAdQEQLPSwqseleNLEERLKALTGKHQDVTAKYNRRRSKikeqnnrdiAGIKD 397
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1494 EKDKALDQKVRsvEHKAPEDtvaemkdrDLEQTDKapEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEA--------- 1564
Cdd:pfam12128 398 KLAKIREARDR--QLAVAED--------DLQALES--ELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQAtatpelllq 465
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 313104325 1565 LEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKAL 1621
Cdd:pfam12128 466 LENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSAL 522
|
|
| OmpH |
smart00935 |
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ... |
1399-1501 |
3.95e-04 |
|
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.
Pssm-ID: 214922 [Multi-domain] Cd Length: 140 Bit Score: 42.96 E-value: 3.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1399 EAVKQQDKALEQKgrdLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKipEEKDKALEQKDTALEQKDKALEpkdKDL 1478
Cdd:smart00935 14 PAGKAAQKQLEKE---FKKRQAELEKLEKELQKLKEKLQKDAATLSEAAR--EKKEKELQKKVQEFQRKQQKLQ---QDL 85
|
90 100
....*....|....*....|....*
gi 313104325 1479 EQKDRVLEQK--EKIpeekDKALDQ 1501
Cdd:smart00935 86 QKRQQEELQKilDKI----NKAIKE 106
|
|
| DUF4515 |
pfam14988 |
Domain of unknown function (DUF4515); This family of proteins is found in bacteria and ... |
1403-1588 |
3.97e-04 |
|
Domain of unknown function (DUF4515); This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 198 and 469 amino acids in length. There are two completely conserved L residues that may be functionally important.
Pssm-ID: 405647 [Multi-domain] Cd Length: 206 Bit Score: 44.37 E-value: 3.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1403 QQDKALEQKGRDLEQK--------DTALEQKDKalepKDKDLEEKDKALEQKDKIPEEKDKalEQKDTALEQKDKALEPK 1474
Cdd:pfam14988 29 QECEEIERRRQELASRytqqtaelQTQLLQKEK----EQASLKKELQALRPFAKLKESQER--EIQDLEEEKEKVRAETA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1475 DKDLEQKDRVLEQKekipeekdkaldqkvRSVEHKAPEDTVAEMKDRDL-EQTDKAPEQKHQAQEQKDKVSE---KKDQA 1550
Cdd:pfam14988 103 EKDREAHLQFLKEK---------------ALLEKQLQELRILELGERATrELKRKAQALKLAAKQALSEFCRsikRENRQ 167
|
170 180 190
....*....|....*....|....*....|....*...
gi 313104325 1551 LEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQED 1588
Cdd:pfam14988 168 LQKELLQLIQETQALEAIKSKLENRKQRLKEEQWYLEA 205
|
|
| PRK00106 |
PRK00106 |
ribonuclease Y; |
1352-1497 |
4.04e-04 |
|
ribonuclease Y;
Pssm-ID: 178867 [Multi-domain] Cd Length: 535 Bit Score: 45.63 E-value: 4.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1352 RTSEQKKEPEPKDEVLQQKDKTLEHKEVVEpkdtaiyqkdEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEP 1431
Cdd:PRK00106 60 KTAKRESKALKKELLLEAKEEARKYREEIE----------QEFKSERQELKQIESRLTERATSLDRKDENLSSKEKTLES 129
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 313104325 1432 KDKDLEEKDKALEQKDKIPE--EKDKALEQKDTAL----EQKDKALEPKDKDL--EQKDRVLEQKEKIPEEKDK 1497
Cdd:PRK00106 130 KEQSLTDKSKHIDEREEQVEklEEQKKAELERVAAlsqaEAREIILAETENKLthEIATRIREAEREVKDRSDK 203
|
|
| GAS |
pfam13851 |
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
1399-1617 |
4.04e-04 |
|
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.
Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 44.13 E-value: 4.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1399 EAVKQQDKALEQKGRDLEQKDTALEQKDKALEpkdKDLEEKDKALEQkdkipEEKDKaleQKDTALEQKDKALEPKDKDL 1478
Cdd:pfam13851 36 AELKKKEERNEKLMSEIQQENKRLTEPLQKAQ---EEVEELRKQLEN-----YEKDK---QSLKNLKARLKVLEKELKDL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1479 EQKDRVLEQK-EKIPEEKDKALDQKVRSVehkapedtvaemkdrdleqtdkapeqkHQAQeQKdkvSEKKDQALEQKywa 1557
Cdd:pfam13851 105 KWEHEVLEQRfEKVERERDELYDKFEAAI---------------------------QDVQ-QK---TGLKNLLLEKK--- 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 313104325 1558 LGQKDEALEQNIQALEEnhqtqeqeslvqedktrkpkMLEEKS--PEKVKAMEEKLEALLEK 1617
Cdd:pfam13851 151 LQALGETLEKKEAQLNE--------------------VLAAANldPDALQAVTEKLEDVLES 192
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1399-1577 |
4.57e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.91 E-value: 4.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1399 EAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIpEEKDKALEQKDTALEQKDKALE-----P 1473
Cdd:COG4717 347 EELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEY-QELKEELEELEEQLEELLGELEelleaL 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1474 KDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEhkapedtvAEMKdrDLEQTDKAPEQKHQAQEQKDKVSEkkdqaLEQ 1553
Cdd:COG4717 426 DEEELEEELEELEEELEELEEELEELREELAELE--------AELE--QLEEDGELAELLQELEELKAELRE-----LAE 490
|
170 180
....*....|....*....|....
gi 313104325 1554 KYWALGQKDEALEQNIQALEENHQ 1577
Cdd:COG4717 491 EWAALKLALELLEEAREEYREERL 514
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
2040-2277 |
5.04e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.08 E-value: 5.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2040 GPTVPPRPEPGPSMEPSLTPPAVPPRAPilskgpsPPLNGNILSCSPDRRSPSPKESgrshwdDSTSDSELEKGAREQPE 2119
Cdd:PHA03247 267 RAPETARGATGPPPPPEAAAPNGAAAPP-------DGVWGAALAGAPLALPAPPDPP------PPAPAGDAEEEDDEDGA 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2120 KEAQSPSPPHpipmgsptlwpetEAHVSPPLDSHlgpARPSLDFPASAFGFSSLQPAPPQLPSP-AEPRSAPCGSLAFS- 2197
Cdd:PHA03247 334 MEVVSPLPRP-------------RQHYPLGFPKR---RRPTWTPPSSLEDLSAGRHHPKRASLPtRKRRSARHAATPFAr 397
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2198 ----GDRALALAPGP---PTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPAlSEGSSSEATTPVISS 2270
Cdd:PHA03247 398 gpggDDQTRPAAPVPasvPTPAPTPVPASAPPPPATPLPSAEPGSDDGPAPPPERQPPAPATEP-APDDPDDATRKALDA 476
|
....*..
gi 313104325 2271 VAERFSP 2277
Cdd:PHA03247 477 LRERRPP 483
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
1452-1640 |
5.34e-04 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 44.90 E-value: 5.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1452 EKDKALEQKDTALEQKDKALEPKDKDLEQK-DRVLEQKEKIPEEKDKaLDQKVRSVEHKApeDTVAEMKDRDLEQTDKAP 1530
Cdd:COG1340 1 SKTDELSSSLEELEEKIEELREEIEELKEKrDELNEELKELAEKRDE-LNAQVKELREEA--QELREKRDELNEKVKELK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1531 EQKHQAQEQKDKVSEKKDQALEQ--KYWALGQKDEALEQNIQALEENHQTqeqESLVQEDktrkpkmlEEKSPEKVKAME 1608
Cdd:COG1340 78 EERDELNEKLNELREELDELRKElaELNKAGGSIDKLRKEIERLEWRQQT---EVLSPEE--------EKELVEKIKELE 146
|
170 180 190
....*....|....*....|....*....|....*.
gi 313104325 1609 EKLEALLE----KTKALGLEESLVQegrAREQEEKY 1640
Cdd:COG1340 147 KELEKAKKalekNEKLKELRAELKE---LRKEAEEI 179
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
1393-1638 |
7.48e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 45.33 E-value: 7.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1393 ALHVKN-----EAVKQQDKALEQKGRDLEQK----DTALEQKDKALEPKDK---DLEEKDKALEQKDKIPE-EKDKALEQ 1459
Cdd:PRK04863 434 DLTADNaedwlEEFQAKEQEATEELLSLEQKlsvaQAAHSQFEQAYQLVRKiagEVSRSEAWDVARELLRRlREQRHLAE 513
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1460 KDTALEQKDKALEpkdKDLEQKDRVleqkEKIPEEKDKALDQkvrsvehkaPEDTVAEMkdrdleqtdkapEQKHQAQEQ 1539
Cdd:PRK04863 514 QLQQLRMRLSELE---QRLRQQQRA----ERLLAEFCKRLGK---------NLDDEDEL------------EQLQEELEA 565
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1540 K-DKVSEKKDQALEQkYWALGQKDEALEQNIQALEenhqTQEQESLVQEDKTRKpkmLEEKSPEKVK---AMEEKLEALL 1615
Cdd:PRK04863 566 RlESLSESVSEARER-RMALRQQLEQLQARIQRLA----ARAPAWLAAQDALAR---LREQSGEEFEdsqDVTEYMQQLL 637
|
250 260
....*....|....*....|...
gi 313104325 1616 EKTKALGLEESLVQEGRAREQEE 1638
Cdd:PRK04863 638 ERERELTVERDELAARKQALDEE 660
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1401-1610 |
8.33e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.01 E-value: 8.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1401 VKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEE-----KDKALEQKDKI-----------PEEKDKAlEQKDTAL 1464
Cdd:TIGR04523 45 IKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQqikdlNDKLKKNKDKInklnsdlskinSEIKNDK-EQKNKLE 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1465 EQKDKALEPKDKDLEQKDRVLEQ---KEKIPEE---KDKALDQKVRSVEHKapEDTVAEMKDrDLEQTDKAPEQKHQAQE 1538
Cdd:TIGR04523 124 VELNKLEKQKKENKKNIDKFLTEikkKEKELEKlnnKYNDLKKQKEELENE--LNLLEKEKL-NIQKNIDKIKNKLLKLE 200
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 313104325 1539 QKDKVSEKKDQ---ALEQKYWALGQKDEALEQNIQalEENHQTQEQESLVQEDKTrKPKMLEEKSPEKVKAMEEK 1610
Cdd:TIGR04523 201 LLLSNLKKKIQknkSLESQISELKKQNNQLKDNIE--KKQQEINEKTTEISNTQT-QLNQLKDEQNKIKKQLSEK 272
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
1389-1638 |
8.35e-04 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 44.89 E-value: 8.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1389 QKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKD---KALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALE 1465
Cdd:pfam07888 35 RLEECLQERAELLQAQEAANRQREKEKERYKRDREQWErqrRELESRVAELKEELRQSREKHEELEEKYKELSASSEELS 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1466 QKDKALEPKDKDLEQKDRVLeqkekipEEKDKALDQKVRSVEhkapedtvAEMkDRDLEQTDKAPEQKHQAQEQKdKVSE 1545
Cdd:pfam07888 115 EEKDALLAQRAAHEARIREL-------EEDIKTLTQRVLERE--------TEL-ERMKERAKKAGAQRKEEEAER-KQLQ 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1546 KKDQALEQKYWALGQKDEALeQNIQALEENHQTQEQES---LVQEDKTRKPKMLE-EKSPEKVKAMEEKLEALLEKTKAL 1621
Cdd:pfam07888 178 AKLQQTEEELRSLSKEFQEL-RNSLAQRDTQVLQLQDTittLTQKLTTAHRKEAEnEALLEELRSLQERLNASERKVEGL 256
|
250
....*....|....*..
gi 313104325 1622 GLEESLVQEGRAREQEE 1638
Cdd:pfam07888 257 GEELSSMAAQRDRTQAE 273
|
|
| Caldesmon |
pfam02029 |
Caldesmon; |
1402-1659 |
8.51e-04 |
|
Caldesmon;
Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 44.86 E-value: 8.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1402 KQQDKALEQKGRDLEQKDTALEQKDKALEPK-DKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQ 1480
Cdd:pfam02029 23 KEEEEPSGQVTESVEPNEHNSYEEDSELKPSgQGGLDEEEAFLDRTAKREERRQKRLQEALERQKEFDPTIADEKESVAE 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1481 KDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDqalEQKYWALGQ 1560
Cdd:pfam02029 103 RKENNEEEENSSWEKEEKRDSRLGRYKEEETEIREKEYQENKWSTEVRQAEEEGEEEEDKSEEAEEVP---TENFAKEEV 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1561 KDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAM----------EEKLEALLEKTKALGLEESLVQE 1630
Cdd:pfam02029 180 KDEKIKKEKKVKYESKVFLDQKRGHPEVKSQNGEEEVTKLKVTTKRRqgglsqsqerEEEAEVFLEAEQKLEELRRRRQE 259
|
250 260
....*....|....*....|....*....
gi 313104325 1631 GRAREQEEKYWRGQDVVQEWQETSPTREE 1659
Cdd:pfam02029 260 KESEEFEKLRQKQQEAELELEELKKKREE 288
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
1981-2167 |
8.54e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 44.87 E-value: 8.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1981 PACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTPP 2060
Cdd:PRK12323 394 AAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVA 473
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2061 AV-----PPRAPILSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPhPIPMGS 2135
Cdd:PRK12323 474 AAaaaapARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPA-AAPAPR 552
|
170 180 190
....*....|....*....|....*....|...
gi 313104325 2136 PTLWPETEAHVSPPLDSHLG-PARPSLDFPASA 2167
Cdd:PRK12323 553 AAAATEPVVAPRPPRASASGlPDMFDGDWPALA 585
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
1365-1700 |
8.62e-04 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 44.89 E-value: 8.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1365 EVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALE 1444
Cdd:PRK01156 371 SIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLN 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1445 QKDKIP------------------EEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEqKEKIpeEKDKALDQKVRSV 1506
Cdd:PRK01156 451 GQSVCPvcgttlgeeksnhiinhyNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLE-SEEI--NKSINEYNKIESA 527
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1507 EH--KAPEDTVAEMKDRDLeqtdkapeqkhQAQEQKDKVSEKKDQALEQKY--W--ALGQKDEALEQNIQAL--EENHQT 1578
Cdd:PRK01156 528 RAdlEDIKIKINELKDKHD-----------KYEEIKNRYKSLKLEDLDSKRtsWlnALAVISLIDIETNRSRsnEIKKQL 596
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1579 QEQESLVQEDKTRKPKmLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAReqeekywrgqdvVQEWQETSPTRE 1658
Cdd:PRK01156 597 NDLESRLQEIEIGFPD-DKSYIDKSIREIENEANNLNNKYNEIQENKILIEKLRGK------------IDNYKKQIAEID 663
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 313104325 1659 EPAGEQKELAPAWEDTspEQDNRYWRGREDVALEQDTYWREL 1700
Cdd:PRK01156 664 SIIPDLKEITSRINDI--EDNLKKSRKALDDAKANRARLEST 703
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1335-1510 |
8.74e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.05 E-value: 8.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1335 LEDIAIKWEDKVPGLK-DRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGR 1413
Cdd:TIGR02168 335 LAEELAELEEKLEELKeELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLED 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1414 DLEQKDTALEQKDKALEPKDKD-----LEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQK 1488
Cdd:TIGR02168 415 RRERLQQEIEELLKKLEEAELKelqaeLEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL 494
|
170 180
....*....|....*....|..
gi 313104325 1489 EKIPEEKDKaLDQKVRSVEHKA 1510
Cdd:TIGR02168 495 ERLQENLEG-FSEGVKALLKNQ 515
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1345-1577 |
9.11e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 45.13 E-value: 9.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1345 KVPGLKDRTSEQKK--------EPEPKDEVLQQKDKTLEHK---EVVEPKDTAIYQKDEALHVKNE---AVKQQDKALEQ 1410
Cdd:PTZ00121 1634 KVEQLKKKEAEEKKkaeelkkaEEENKIKAAEEAKKAEEDKkkaEEAKKAEEDEKKAAEALKKEAEeakKAEELKKKEAE 1713
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1411 KGRDLEQ-KDTALEQKDKALEPKDKDLEEKDKALEQKdKIPEEKDKAleQKDTALEQKDKALEPKDKDLEQKDRVLEQKE 1489
Cdd:PTZ00121 1714 EKKKAEElKKAEEENKIKAEEAKKEAEEDKKKAEEAK-KDEEEKKKI--AHLKKEEEKKAEEIRKEKEAVIEEELDEEDE 1790
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1490 KIPEEKDKAL-DQKVRSV--------------EHKAPEDT----VAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQA 1550
Cdd:PTZ00121 1791 KRRMEVDKKIkDIFDNFAniieggkegnlvinDSKEMEDSaikeVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADF 1870
|
250 260
....*....|....*....|....*..
gi 313104325 1551 LEQKYwalgqKDEALEQNIQALEENHQ 1577
Cdd:PTZ00121 1871 NKEKD-----LKEDDEEEIEEADEIEK 1892
|
|
| ComEC |
COG2333 |
DNA uptake channel protein ComEC C-terminal domain, metallo-beta-lactamase superfamily ... |
46-149 |
1.08e-03 |
|
DNA uptake channel protein ComEC C-terminal domain, metallo-beta-lactamase superfamily [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 441904 [Multi-domain] Cd Length: 253 Bit Score: 43.31 E-value: 1.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 46 GRGDSALF-AVNGFNILVDGGSDRKSCFWKLV-------RHLDRIDSVLLTHIGADNLPGINGLLQR-KVAELEE-EQSQ 115
Cdd:COG2333 9 GQGDAILIrTPDGKTILIDTGPRPSFDAGERVvlpylraLGIRRLDLLVLTHPDADHIGGLAAVLEAfPVGRVLVsGPPD 88
|
90 100 110
....*....|....*....|....*....|....
gi 313104325 116 GSSSYSDWVKNLISPELGVVFFNVPEKLRLPDAS 149
Cdd:COG2333 89 TSETYERLLEALKEKGIPVRPCRAGDTWQLGGVR 122
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
1433-1640 |
1.14e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 44.56 E-value: 1.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1433 DKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQkdkaLEPK----DKDLEQKDRVLEQKEKIPEEKDK------ALDQK 1502
Cdd:COG3096 888 DETLADRLEELREELDAAQEAQAFIQQHGKALAQ----LEPLvavlQSDPEQFEQLQADYLQAKEQQRRlkqqifALSEV 963
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1503 VRSVEHKAPEDTVAEM-KDRDLeqTDKAPEQKHQAQEQKdkvsEKKDQALEQkywALGQKDEALeQNIQALEENHQT--- 1578
Cdd:COG3096 964 VQRRPHFSYEDAVGLLgENSDL--NEKLRARLEQAEEAR----REAREQLRQ---AQAQYSQYN-QVLASLKSSRDAkqq 1033
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1579 --QEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEAL------LEKTKALGLEESLVQEGRAREQEEKY 1640
Cdd:COG3096 1034 tlQELEQELEELGVQADAEAEERARIRRDELHEELSQNrsrrsqLEKQLTRCEAEMDSLQKRLRKAERDY 1103
|
|
| YqiK |
COG2268 |
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]; |
1401-1614 |
1.31e-03 |
|
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 44.09 E-value: 1.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1401 VKQQDKALEQKGRDL-------EQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIpEEKDKALEQKDTALEQKDKALEP 1473
Cdd:COG2268 179 LEDENNYLDALGRRKiaeiirdARIAEAEAERETEIAIAQANREAEEAELEQEREI-ETARIAEAEAELAKKKAEERREA 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1474 KDKDLEQKDRVLEQKekipEEKDKALDQKVRSVEhKAPEDTVAEM-KDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQAle 1552
Cdd:COG2268 258 ETARAEAEAAYEIAE----ANAEREVQRQLEIAE-REREIELQEKeAEREEAELEADVRKPAEAEKQAAEAEAEAEAE-- 330
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 313104325 1553 qkywALGQKDEALEQNIQALEENHQTQEQESLVQedktrkpkMLEEKSPEKVKAMEEKLEAL 1614
Cdd:COG2268 331 ----AIRAKGLAEAEGKRALAEAWNKLGDAAILL--------MLIEKLPEIAEAAAKPLEKI 380
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
2190-2452 |
1.45e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 44.10 E-value: 1.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2190 PCGSLAFSGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPALsegsssEATTPVIS 2269
Cdd:PRK12323 365 PGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAP------EALAAARQ 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2270 SVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPslpgdmgdgilpchlecseaATEKPSP 2349
Cdd:PRK12323 439 ASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAP--------------------ADDDPPP 498
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2350 FQVPSEDCAANGPTETSPNPPGpapakaeneeaaacpaWERGAWPEGAERSSRPDTLLSPEQPVcpaggsggPPSSASPE 2429
Cdd:PRK12323 499 WEELPPEFASPAPAQPDAAPAG----------------WVAESIPDPATADPDDAFETLAPAPA--------AAPAPRAA 554
|
250 260
....*....|....*....|...
gi 313104325 2430 VEAGPQGCATEPRPHRGELSPSF 2452
Cdd:PRK12323 555 AATEPVVAPRPPRASASGLPDMF 577
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1509-1667 |
1.50e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.99 E-value: 1.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1509 KAPEDTVAEMKD--RDLEQTDKAPEQKHQAQEQKDKVSEKKdQALEQKYWALGQKDEALEQNIQALEenhQTQEQESLVQ 1586
Cdd:COG4717 64 RKPELNLKELKEleEELKEAEEKEEEYAELQEELEELEEEL-EELEAELEELREELEKLEKLLQLLP---LYQELEALEA 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1587 EdktrkpkmLEEKsPEKVKAMEEKLEALLEKTKAL-GLEESLVQEGRAREQEEKYWRgQDVVQEWQETSPTREEPAGEQK 1665
Cdd:COG4717 140 E--------LAEL-PERLEELEERLEELRELEEELeELEAELAELQEELEELLEQLS-LATEEELQDLAEELEELQQRLA 209
|
..
gi 313104325 1666 EL 1667
Cdd:COG4717 210 EL 211
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1335-1574 |
1.74e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 43.88 E-value: 1.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1335 LEDIaikwEDKVPGLKDR--TSEQKKEPEPKDEVLQQKDKTLEhkEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKG 1412
Cdd:PRK02224 484 LEDL----EEEVEEVEERleRAEDLVEAEDRIERLEERREDLE--ELIAERRETIEEKRERAEELRERAAELEAEAEEKR 557
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1413 rdlEQKDTALEQKDKALEPK---DKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKE 1489
Cdd:PRK02224 558 ---EAAAEAEEEAEEAREEVaelNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRE 634
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1490 KIPEekdkaLDQKVrsvehkapedtvaemkdrDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYwALGQKDEALEQNI 1569
Cdd:PRK02224 635 RKRE-----LEAEF------------------DEARIEEAREDKERAEEYLEQVEEKLDELREERD-DLQAEIGAVENEL 690
|
....*
gi 313104325 1570 QALEE 1574
Cdd:PRK02224 691 EELEE 695
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1378-1634 |
1.81e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.85 E-value: 1.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1378 EVVEPKDTAIYQ-------KDEALHVKNEAVKQ-QDKALEQKGRDLEQKDTALEQKDKALEpkdKDLEEKDKALE---QK 1446
Cdd:COG3206 128 TVEPVKGSNVIEisytspdPELAAAVANALAEAyLEQNLELRREEARKALEFLEEQLPELR---KELEEAEAALEefrQK 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1447 DKI--PEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQK-----EKIPEEKDKALDQKVRSVEHKApEDTVAEMK 1519
Cdd:COG3206 205 NGLvdLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQlgsgpDALPELLQSPVIQQLRAQLAEL-EAELAELS 283
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1520 DRdleQTDKAPEQKhQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEek 1599
Cdd:COG3206 284 AR---YTPNHPDVI-ALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLE-- 357
|
250 260 270
....*....|....*....|....*....|....*
gi 313104325 1600 spEKVKAMEEKLEALLEKTKALGLEESLvQEGRAR 1634
Cdd:COG3206 358 --REVEVARELYESLLQRLEEARLAEAL-TVGNVR 389
|
|
| PRK12727 |
PRK12727 |
flagellar biosynthesis protein FlhF; |
2099-2322 |
2.08e-03 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 237182 [Multi-domain] Cd Length: 559 Bit Score: 43.44 E-value: 2.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2099 SHWDDSTSDSELEKGAREQPEKEAQSPSPPHPipmgsPTLWPETEAHVSPPLDSHLGPARPSLDFPASAFGFSSLQPAPP 2178
Cdd:PRK12727 44 SNYDEELVQRALETARSDTPATAAAPAPAPQA-----PTKPAAPVHAPLKLSANANMSQRQRVASAAEDMIAAMALRQPV 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2179 QLPSPAePRSAPCGSLAFSGDRALALAPGPPTRTrhdeylevtkAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEG 2258
Cdd:PRK12727 119 SVPRQA-PAAAPVRAASIPSPAAQALAHAAAVRT----------APRQEHALSAVPEQLFADFLTTAPVPRAPVQAPVVA 187
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 313104325 2259 SSSE-----ATTPVISSVAERFSPSLEAAEQESGE-LDPGMEPAAhslwdLTPLSPAPPASLDLA----LAPAP 2322
Cdd:PRK12727 188 APAPvpaiaAALAAHAAYAQDDDEQLDDDGFDLDDaLPQILPPAA-----LPPIVVAPAAPAALAavaaAAPAP 256
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
1355-1683 |
2.10e-03 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 43.46 E-value: 2.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1355 EQKKEPEPKDEVLQQKDKTLEHK-EVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKAL-EPK 1432
Cdd:NF033838 195 EEAKEPRDEEKIKQAKAKVESKKaEATRLEKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKRGVLgEPA 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1433 DKDLEEKDKalEQKDKIPEEK-----DKALEQKDTALEQKDKALEPKDKDLEQKDRvleqkEKIPEEKDKALDQKVRSVE 1507
Cdd:NF033838 275 TPDKKENDA--KSSDSSVGEEtlpspSLKPEKKVAEAEKKVEEAKKKAKDQKEEDR-----RNYPTNTYKTLELEIAESD 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1508 HKAPEdtvAEMKdrDLEQTDKAPEQKHQAQEQKDKVSEKKDQALeqkywalgQKDEALEQNIQALEENHQTQEQESLVQE 1587
Cdd:NF033838 348 VKVKE---AELE--LVKEEAKEPRNEEKIKQAKAKVESKKAEAT--------RLEKIKTDRKKAEEEAKRKAAEEDKVKE 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1588 DKTRKPKMLEEKSPEKVKAMEEKLEallEKTKALGLEESLVQEGRAREQEEKYWRgqdvvqewqetsPTREEPAGEQKEL 1667
Cdd:NF033838 415 KPAEQPQPAPAPQPEKPAPKPEKPA---EQPKAEKPADQQAEEDYARRSEEEYNR------------LTQQQPPKTEKPA 479
|
330
....*....|....*.
gi 313104325 1668 APAWEDTSPEQDNRYW 1683
Cdd:NF033838 480 QPSTPKTGWKQENGMW 495
|
|
| rplD |
PRK14907 |
50S ribosomal protein L4; Provisional |
320-408 |
2.14e-03 |
|
50S ribosomal protein L4; Provisional
Pssm-ID: 184900 [Multi-domain] Cd Length: 295 Bit Score: 43.01 E-value: 2.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 320 KESLKATT--KTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIK 397
Cdd:PRK14907 6 KTTKKKTTeeKKPAAKKATTSKETAKTKKTAKTTSTKAAKKAAKVKKTKSVKTTTKKVTVKFEKTESVKKESVAKKTVKK 85
|
90
....*....|.
gi 313104325 398 DKVGKKHLKEK 408
Cdd:PRK14907 86 EAVSAEVFEAS 96
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1354-1595 |
2.17e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.21 E-value: 2.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1354 SEQKKEPEPKDEVLQQKDKTLEhkevvepkdtaiyQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKD 1433
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELE-------------KELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAEL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1434 KDLEEKDKALEQKDkipEEKDKALEQKDTALEQKDKALEPK----DKDLEQKDRVLE-QKEKIPEEKDKALDQKVRSVEH 1508
Cdd:COG4942 86 AELEKEIAELRAEL---EAQKEELAELLRALYRLGRQPPLAlllsPEDFLDAVRRLQyLKYLAPARREQAEELRADLAEL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1509 KAPEDTVAEMKDR------DLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQE 1582
Cdd:COG4942 163 AALRAELEAERAEleallaELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
250
....*....|...
gi 313104325 1583 SLVQEDKTRKPKM 1595
Cdd:COG4942 243 TPAAGFAALKGKL 255
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1430-1621 |
2.23e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 43.47 E-value: 2.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1430 EPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKvrSVEHK 1509
Cdd:TIGR04523 32 DTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSD--LSKIN 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1510 APEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSE---KKDQALEQkywaLGQKDEALEQNIQALE-ENHQTQEQESLV 1585
Cdd:TIGR04523 110 SEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTeikKKEKELEK----LNNKYNDLKKQKEELEnELNLLEKEKLNI 185
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 313104325 1586 QE--DKTRKPKM--------LEEKSpEKVKAMEEKLEALLEKTKAL 1621
Cdd:TIGR04523 186 QKniDKIKNKLLklelllsnLKKKI-QKNKSLESQISELKKQNNQL 230
|
|
| RNase_Y_N |
pfam12072 |
RNase Y N-terminal region; |
1355-1445 |
2.63e-03 |
|
RNase Y N-terminal region;
Pssm-ID: 463456 [Multi-domain] Cd Length: 201 Bit Score: 41.80 E-value: 2.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1355 EQKKEP--EPKDEVLQQKDKTleHKEVVEPK------DTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKD 1426
Cdd:pfam12072 49 TKKKEAllEAKEEIHKLRAEA--ERELKERRnelqrqERRLLQKEETLDRKDESLEKKEESLEKKEKELEAQQQQLEEKE 126
|
90
....*....|....*....
gi 313104325 1427 KALEPKdkdLEEKDKALEQ 1445
Cdd:pfam12072 127 EELEEL---IEEQRQELER 142
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
1403-1533 |
2.65e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 43.28 E-value: 2.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1403 QQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEE-KDKALEQ-----KDKIPEEKDKALE--------QKDTALEQKD 1468
Cdd:PRK00409 527 ELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEeEDKLLEEaekeaQQAIKEAKKEADEiikelrqlQKGGYASVKA 606
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1469 KALEPKDKDLEQKDRVLEQKEKIPEEKDKAL---DQ-KVRSVEHKApedTVAEMKD-----------------RDLEQTD 1527
Cdd:PRK00409 607 HELIEARKRLNKANEKKEKKKKKQKEKQEELkvgDEvKYLSLGQKG---EVLSIPDdkeaivqagimkmkvplSDLEKIQ 683
|
....*.
gi 313104325 1528 KAPEQK 1533
Cdd:PRK00409 684 KPKKKK 689
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
1363-1490 |
2.69e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 43.28 E-value: 2.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1363 KDEVLQQKDKTLEHKEVVEpkdtaIYQKDEAlhvkNEAVKQQDKALEQKGRDLEQKdtaleQKDKALEPKDKDLEEKDKA 1442
Cdd:PRK00409 550 KEELEEKKEKLQEEEDKLL-----EEAEKEA----QQAIKEAKKEADEIIKELRQL-----QKGGYASVKAHELIEARKR 615
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 313104325 1443 LEQKDKIPEEKDKALEQKDTALEQKDKALEPKdkdLEQKDRVLEQKEK 1490
Cdd:PRK00409 616 LNKANEKKEKKKKKQKEKQEELKVGDEVKYLS---LGQKGEVLSIPDD 660
|
|
| CCDC34 |
pfam13904 |
Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several ... |
1531-1661 |
2.81e-03 |
|
Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several conserved tryptophan residues. The function is not known.
Pssm-ID: 464032 [Multi-domain] Cd Length: 221 Bit Score: 42.00 E-value: 2.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1531 EQKHQAQ----EQKDKVSEKKDQALEQKY--WAlgqKDEALEQNIQAlEENHQTQEQESLVQEDKTRKPKMLEEKSPEKV 1604
Cdd:pfam13904 69 QKELQAQkeerEKEEQEAELRKRLAKEKYqeWL---QRKARQQTKKR-EESHKQKAAESASKSLAKPERKVSQEEAKEVL 144
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 313104325 1605 KAMEEKLEALLEKTKalgLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPA 1661
Cdd:pfam13904 145 QEWERKKLEQQQRKR---EEEQREQLKKEEEEQERKQLAEKAWQKWMKNVKNKPKPV 198
|
|
| Borrelia_P83 |
pfam05262 |
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins. |
1349-1495 |
3.08e-03 |
|
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
Pssm-ID: 114011 [Multi-domain] Cd Length: 489 Bit Score: 43.07 E-value: 3.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1349 LKDRTSE---QKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEAlhvknEAVKQQDKALEQKGRDLEQKdtaleQK 1425
Cdd:pfam05262 203 LKERESQedaKRAQQLKEELDKKQIDADKAQQKADFAQDNADKQRDEV-----RQKQQEAKNLPKPADTSSPK-----ED 272
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 313104325 1426 DKALEPKDKDLEEKDKALEQKDkipEEKDKALEQK--DTALEQKDKALEPKDKDLE-QKDR--VLEQKEKIPEEK 1495
Cdd:pfam05262 273 KQVAENQKREIEKAQIEIKKND---EEALKAKDHKafDLKQESKASEKEAEDKELEaQKKRepVAEDLQKTKPQV 344
|
|
| Tropomyosin_1 |
pfam12718 |
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and ... |
1438-1620 |
3.46e-03 |
|
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and Tpm2, biochemical and sequence analyses indicate that Tpm2p spans four actin monomers along a filament, whereas Tpm1p spans five. Despite its shorter length, Tpm2p can compete with Tpm1p for binding to F-actin. Over-expression of Tpm2p in vivo alters the axial budding of haploids to a bipolar pattern, and this can be partially suppressed by co-over-expression of Tpm1p. This suggests distinct functions for the two tropomyosins, and indicates that the ratio between them is important for correct morphogenesis. The family also contains higher eukaryote Tpm3 members.
Pssm-ID: 403808 [Multi-domain] Cd Length: 142 Bit Score: 40.37 E-value: 3.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1438 EKDKALEQKDKIpEEKDKALEQKDTALEQKDKALEPKDKDLEqkdrvleqkekipEEKDKAldqkvrsvehkapEDTVAE 1517
Cdd:pfam12718 8 EAENAQERAEEL-EEKVKELEQENLEKEQEIKSLTHKNQQLE-------------EEVEKL-------------EEQLKE 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1518 MKDrdleqtdkAPEQKHQAQEQKDKVSeKKDQALEqkywalgqkdEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLE 1597
Cdd:pfam12718 61 AKE--------KAEESEKLKTNNENLT-RKIQLLE----------EELEESDKRLKETTEKLRETDVKAEHLERKVQALE 121
|
170 180
....*....|....*....|...
gi 313104325 1598 EKSPEkvkaMEEKLEALLEKTKA 1620
Cdd:pfam12718 122 QERDE----WEKKYEELEEKYKE 140
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
1478-1617 |
3.77e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 42.77 E-value: 3.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1478 LEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKH------QAQEQKDKVSEKKDQAL 1551
Cdd:PRK12705 25 LKKRQRLAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQReeerlvQKEEQLDARAEKLDNLE 104
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 313104325 1552 EQkywaLGQKDEALEQNIQALEE-NHQ---------TQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEK 1617
Cdd:PRK12705 105 NQ----LEEREKALSARELELEElEKQldnelyrvaGLTPEQARKLLLKLLDAELEEEKAQRVKKIEEEADLEAER 176
|
|
| GBP_C |
pfam02841 |
Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral ... |
1478-1637 |
4.04e-03 |
|
Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral guanylate-binding protein (GBP) is induced by interferon-gamma during macrophage induction. This family contains GBP1 and GPB2, both GTPases capable of binding GTP, GDP and GMP.
Pssm-ID: 460721 [Multi-domain] Cd Length: 297 Bit Score: 41.89 E-value: 4.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1478 LEQKDRVLEQKEKIPEEKDKALD--QKVRSvEHKAPEDTvaemkdrdLEQTDKAPEqkhqAQEQKDKVSEKKDQALEQKY 1555
Cdd:pfam02841 154 LEERDKLEAKYNQVPRKGVKAEEvlQEFLQ-SKEAVEEA--------ILQTDQALT----AKEKAIEAERAKAEAAEAEQ 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1556 WALGQKDEALEQNIQALEEnhQTQEQESLVQEdktrkpKMLEEKspEKVKAMEEKLEALLEKTKALGLEESLVQEGRARE 1635
Cdd:pfam02841 221 ELLREKQKEEEQMMEAQER--SYQEHVKQLIE------KMEAER--EQLLAEQERMLEHKLQEQEELLKEGFKTEAESLQ 290
|
..
gi 313104325 1636 QE 1637
Cdd:pfam02841 291 KE 292
|
|
| TolA |
COG3064 |
Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis]; |
1363-1698 |
4.37e-03 |
|
Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442298 [Multi-domain] Cd Length: 485 Bit Score: 42.33 E-value: 4.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1363 KDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKdtALEQKDKALEPKDKDLEEKDKA 1442
Cdd:COG3064 1 AQEALEEKAAEAAAQERLEQAEAEKRAAAEAEQKAKEEAEEERLAELEAKRQAEEE--AREAKAEAEQRAAELAAEAAKK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1443 LEQKdkipeEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRD 1522
Cdd:COG3064 79 LAEA-----EKAAAEAEKKAAAEKAKAAKEAEAAAAAEKAAAAAEKEKAEEAKRKAEEEAKRKAEEERKAAEAEAAAKAE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1523 LEQTDKAPE-QKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSP 1601
Cdd:COG3064 154 AEAARAAAAaAAAAAAAAARAAAGAAAALVAAAAAAVEAADTAAAAAAALAAAAAAAAADAALLALAVAARAAAASREAA 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1602 EKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNR 1681
Cdd:COG3064 234 LAAVEATEEAALGGAEEAADLAAVGVLGAALAAAAAGAAALSSGLVVVAAALAGLAAAAAGLVLDDSAALAAELLGAVAA 313
|
330
....*....|....*..
gi 313104325 1682 YWRGREDVALEQDTYWR 1698
Cdd:COG3064 314 EEAVLAAAAAAGALVVR 330
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
1363-1617 |
5.04e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 42.22 E-value: 5.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1363 KDEVL---QQKDKTLE--HKE-VVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQ----KDTALEQKDKALEPK 1432
Cdd:PRK05771 8 KVLIVtlkSYKDEVLEalHELgVVHIEDLKEELSNERLRKLRSLLTKLSEALDKLRSYLPKlnplREEKKKVSVKSLEEL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1433 DKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEP------KDKDLEQKDRVLEQKEKIPEEKDKALDQKVRS- 1505
Cdd:PRK05771 88 IKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEPwgnfdlDLSLLLGFKYVSVFVGTVPEDKLEELKLESDVe 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1506 -----------------VEHKAPEDTVAEMKDRDLE----QTDKAP-EQKHQAQEQKDKVSEKKDQALEQkywaLGQKDE 1563
Cdd:PRK05771 168 nveyistdkgyvyvvvvVLKELSDEVEEELKKLGFErlelEEEGTPsELIREIKEELEEIEKERESLLEE----LKELAK 243
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 313104325 1564 ALEQNIQALEE--NHQTQEQESLVQEDKTRKPKMLEEKSPEKvkaMEEKLEALLEK 1617
Cdd:PRK05771 244 KYLEELLALYEylEIELERAEALSKFLKTDKTFAIEGWVPED---RVKKLKELIDK 296
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1367-1517 |
5.56e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.06 E-value: 5.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1367 LQQKDKTL--------EHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALE----PKD- 1433
Cdd:COG1579 12 LQELDSELdrlehrlkELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGnvrnNKEy 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1434 ----KDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHK 1509
Cdd:COG1579 92 ealqKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAK 171
|
....*...
gi 313104325 1510 APEDTVAE 1517
Cdd:COG1579 172 IPPELLAL 179
|
|
| PRK13808 |
PRK13808 |
adenylate kinase; Provisional |
292-408 |
6.25e-03 |
|
adenylate kinase; Provisional
Pssm-ID: 172341 [Multi-domain] Cd Length: 333 Bit Score: 41.41 E-value: 6.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 292 PVATQKDLASGAVPTNLKPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEArselAKELAKTEKKAKESSEKPP 371
Cdd:PRK13808 207 AAKSGAKKASAKAKSAAKKVSKKKAAKTAVSAKKAAKTAAKAAKKAKKTAKKALKKA----AKAVKKAAKKAAKAAAKAA 282
|
90 100 110
....*....|....*....|....*....|....*..
gi 313104325 372 EKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEK 408
Cdd:PRK13808 283 KGAAKATKGKAKAKKKAGKKAAAGSKAKATAKAPKRG 319
|
|
| Tropomyosin_1 |
pfam12718 |
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and ... |
1522-1640 |
6.49e-03 |
|
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and Tpm2, biochemical and sequence analyses indicate that Tpm2p spans four actin monomers along a filament, whereas Tpm1p spans five. Despite its shorter length, Tpm2p can compete with Tpm1p for binding to F-actin. Over-expression of Tpm2p in vivo alters the axial budding of haploids to a bipolar pattern, and this can be partially suppressed by co-over-expression of Tpm1p. This suggests distinct functions for the two tropomyosins, and indicates that the ratio between them is important for correct morphogenesis. The family also contains higher eukaryote Tpm3 members.
Pssm-ID: 403808 [Multi-domain] Cd Length: 142 Bit Score: 39.60 E-value: 6.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1522 DLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKywaLGQKDEALEQNIQALEENHQTQEQ-ESLvqedkTRKPKMLEEKS 1600
Cdd:pfam12718 18 ELEEKVKELEQENLEKEQEIKSLTHKNQQLEEE---VEKLEEQLKEAKEKAEESEKLKTNnENL-----TRKIQLLEEEL 89
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 313104325 1601 PEKVKAMEEKLEALLEKTKALGLEESLVQ--EGRAREQEEKY 1640
Cdd:pfam12718 90 EESDKRLKETTEKLRETDVKAEHLERKVQalEQERDEWEKKY 131
|
|
| PspA_IM30 |
pfam04012 |
PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent ... |
1436-1639 |
6.81e-03 |
|
PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent transcription. The PspA protein, a negative regulator of the Escherichia coli phage shock psp operon, is produced when virulence factors are exported through secretins in many Gram-negative pathogenic bacteria and its homolog in plants, VIPP1, plays a critical role in thylakoid biogenesis, essential for photosynthesis. Activation of transcription by the enhancer-dependent bacterial sigma(54) containing RNA polymerase occurs through ATP hydrolysis-driven protein conformational changes enabled by activator proteins that belong to the large AAA(+) mechanochemical protein family. It has been shown that PspA directly and specifically acts upon and binds to the AAA(+) domain of the PspF transcription activator.
Pssm-ID: 461130 [Multi-domain] Cd Length: 215 Bit Score: 40.43 E-value: 6.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1436 LEEKDKALEQkdkIPEEKDKALEQKDTALEQKdKALEpkdKDLEQK-DRVLEQKEKIPEEKDKALDQKvrsvEHKAPEDT 1514
Cdd:pfam04012 20 AEDPEKMLEQ---AIRDMQSELVKARQALAQT-IARQ---KQLERRlEQQTEQAKKLEEKAQAALTKG----NEELAREA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1515 VAEMKDrdLEQTDKAPEQKH-QAQEQKDKVsEKKDQALEQKYWALGQKDEALEQNIQAleENHQTQEQESLVQEDKTRKP 1593
Cdd:pfam04012 89 LAEKKS--LEKQAEALETQLaQQRSAVEQL-RKQLAALETKIQQLKAKKNLLKARLKA--AKAQEAVQTSLGSLSTSSAT 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 313104325 1594 KMLEEKSpEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEK 1639
Cdd:pfam04012 164 DSFERIE-EKIEEREARADAAAELASAVDLDAKLEQAGIQMEVSED 208
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
1350-1446 |
6.91e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 41.69 E-value: 6.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1350 KDRTSEQKKEPEPKDEVLQQKDKTLEHKEvvepkdtaiyqkdealhvknEAVKQQDKALEQKGRDLEQKDTALEQKDKAL 1429
Cdd:PRK12704 67 HKLRNEFEKELRERRNELQKLEKRLLQKE--------------------ENLDRKLELLEKREEELEKKEKELEQKQQEL 126
|
90
....*....|....*..
gi 313104325 1430 EPKDKDLEEKDKALEQK 1446
Cdd:PRK12704 127 EKKEEELEELIEEQLQE 143
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
1355-1636 |
8.05e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 41.75 E-value: 8.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1355 EQKKEPEPKDEVLQQKDKTLEHKEVVEP--KDTAIYQKDEALHVKNEAVKQQDKalEQKGRDLEQKDTALEQKDKALEPK 1432
Cdd:pfam12128 636 KASREETFARTALKNARLDLRRLFDEKQseKDKKNKALAERKDSANERLNSLEA--QLKQLDKKHQAWLEEQKEQKREAR 713
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1433 DKDLeEKDKALEqkdkipEEKDKALEQKDTALEQKDKALEPKDKDLE-QKDRVLEQKEkIPEEKDKALDQKVRSVEHKAP 1511
Cdd:pfam12128 714 TEKQ-AYWQVVE------GALDAQLALLKAAIAARRSGAKAELKALEtWYKRDLASLG-VDPDVIAKLKREIRTLERKIE 785
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1512 EDTVAEMKDRDLEQTdkapeQKHQAQEQKDKVSEKKDQaleqkywaLGQKDEALEQNIQALEENHQTQEQESLVQEDKTR 1591
Cdd:pfam12128 786 RIAVRRQEVLRYFDW-----YQETWLQRRPRLATQLSN--------IERAISELQQQLARLIADTKLRRAKLEMERKASE 852
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 313104325 1592 KPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQ 1636
Cdd:pfam12128 853 KQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIGERLAQLED 897
|
|
| GBP_C |
pfam02841 |
Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral ... |
1396-1504 |
8.29e-03 |
|
Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral guanylate-binding protein (GBP) is induced by interferon-gamma during macrophage induction. This family contains GBP1 and GPB2, both GTPases capable of binding GTP, GDP and GMP.
Pssm-ID: 460721 [Multi-domain] Cd Length: 297 Bit Score: 41.12 E-value: 8.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1396 VKNEAVKQQD-KALEQKGRDLEQKDTALEQKDKALEPKdkdlEEKDKALEQKDKIPEEKDKALEQKdtaLEQKDKALEPK 1474
Cdd:pfam02841 172 VKAEEVLQEFlQSKEAVEEAILQTDQALTAKEKAIEAE----RAKAEAAEAEQELLREKQKEEEQM---MEAQERSYQEH 244
|
90 100 110
....*....|....*....|....*....|.
gi 313104325 1475 DKDLEQKdrvLEQ-KEKIPEEKDKALDQKVR 1504
Cdd:pfam02841 245 VKQLIEK---MEAeREQLLAEQERMLEHKLQ 272
|
|
| TACC_C |
pfam05010 |
Transforming acidic coiled-coil-containing protein (TACC), C-terminal; This entry represents a ... |
1459-1612 |
8.74e-03 |
|
Transforming acidic coiled-coil-containing protein (TACC), C-terminal; This entry represents a C-terminal domain found in the the proteins TACC 1, 2 and 3 (TACC1-3). TACC1 is found concentrated in the centrosomes of eukaryotes which may play a conserved role in organizing centrosomal microtubules. The human TACC proteins have been linked to cancer and TACC2 has been identified as a possible tumour suppressor (AZU-1). TACC 3 from Xenopus laevis, also known as maskin, associates XMAP215 and promotes efficient microtubule elongation during mitosis. Maskin is also found to bind CPEB and elF-4E. Interestingly, the functional homolog (Alp7) in Schizosaccharomyces pombe (not included in this entry) has been shown to be required for organization of bipolar spindles.
Pssm-ID: 461517 [Multi-domain] Cd Length: 201 Bit Score: 40.04 E-value: 8.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1459 QKDtaleqKDKALEPKDKDLEQKDR-VLEQKEKIpEEKDKALDQKVRSVEhkAPEDTVAEMkdrdleqTDKAPEQKHQAQ 1537
Cdd:pfam05010 3 QKD-----MDAALEKARNEIEEKELeINELKAKY-EELRRENLEMRKIVA--EFEKTIAQM-------IEEKQKQKELEH 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1538 EQKDKVSEKKDQAL------EQKYWALGQKDEALEQNIQALEENHQTQEQEslVQEDKTRKPKmlEEKSPEKVKA-MEEK 1610
Cdd:pfam05010 68 AEIQKVLEEKDQALadlnsvEKSFSDLFKRYEKQKEVISGYKKNEESLKKC--AQDYLARIKK--EEQRYQALKAhAEEK 143
|
..
gi 313104325 1611 LE 1612
Cdd:pfam05010 144 LD 145
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
1403-1638 |
8.84e-03 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 40.95 E-value: 8.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1403 QQDK---ALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQ-----KDKIPEEKDKA--------LEQKDTALEQ 1466
Cdd:pfam15905 91 EQDKrlqALEEELEKVEAKLNAAVREKTSLSASVASLEKQLLELTRvnellKAKFSEDGTQKkmsslsmeLMKLRNKLEA 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1467 KDKALEPKDKDLEQKDRVLEQ-----KEKIPEEKDKALDQKVRSVEHKApedtvaemkdrDLEQTDKAPEQKHQAQEQKD 1541
Cdd:pfam15905 171 KMKEVMAKQEGMEGKLQVTQKnlehsKGKVAQLEEKLVSTEKEKIEEKS-----------ETEKLLEYITELSCVSEQVE 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1542 KVSEKKDQALEqkywALGQKDEALEQNIQALEENhqTQEQESLVqEDKTRKPKMLEEKSPEKVKAMEEKLEALleKTKAL 1621
Cdd:pfam15905 240 KYKLDIAQLEE----LLKEKNDEIESLKQSLEEK--EQELSKQI-KDLNEKCKLLESEKEELLREYEEKEQTL--NAELE 310
|
250
....*....|....*..
gi 313104325 1622 GLEESLVQEgrarEQEE 1638
Cdd:pfam15905 311 ELKEKLTLE----EQEH 323
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
2041-2257 |
9.76e-03 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 41.58 E-value: 9.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2041 PTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSpplngniLSCSPDRRSPSPKESgrshwdDSTSDSELEKGAREQPEK 2120
Cdd:PHA03379 485 PGVVQDGRPACAPVPAPAGPIVRPWEASLSQVPG-------VAFAPVMPQPMPVEP------VPVPTVALERPVCPAPPL 551
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 2121 EA-QSPSPPHPIPMGS----PTLWPETEAHVSPPLDSHLGPARPSldfPASAFGFSSLQPAPPQLPS---------PAEP 2186
Cdd:PHA03379 552 IAmQGPGETSGIVRVRerwrPAPWTPNPPRSPSQMSVRDRLARLR---AEAQPYQASVEVQPPQLTQvspqqpmeyPLEP 628
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 313104325 2187 RSAPCGSLAFSGDRALALAPGPPtrtrhdeyleVTKAPSLDSSLPQLPSPSSPGAPLLSN-LPRPASPALSE 2257
Cdd:PHA03379 629 EQQMFPGSPFSQVADVMRAGGVP----------AMQPQYFDLPLQQPISQGAPLAPLRASmGPVPPVPATQP 690
|
|
| tolA |
PRK09510 |
cell envelope integrity inner membrane protein TolA; Provisional |
1458-1620 |
9.80e-03 |
|
cell envelope integrity inner membrane protein TolA; Provisional
Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 40.95 E-value: 9.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1458 EQKDT--ALEQKDKALEPKDKDLEQKDRVLEQKEK-IPEEKDKALDQKvrsvehKAPEdtvaemkdrdlEQTDKAPEQKH 1534
Cdd:PRK09510 70 QQKSAkrAEEQRKKKEQQQAEELQQKQAAEQERLKqLEKERLAAQEQK------KQAE-----------EAAKQAALKQK 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104325 1535 QAQEQKDKVSE--KKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEkSPEKVKAMEEKLE 1612
Cdd:PRK09510 133 QAEEAAAKAAAaaKAKAEAEAKRAAAAAKKAAAEAKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAE-AKKKAEAEAKKKA 211
|
....*...
gi 313104325 1613 ALLEKTKA 1620
Cdd:PRK09510 212 AAEAKKKA 219
|
|
| |
