|
Name |
Accession |
Description |
Interval |
E-value |
| LeuS |
COG0495 |
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA ... |
1-841 |
0e+00 |
|
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440261 [Multi-domain] Cd Length: 826 Bit Score: 1173.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 1 MEKEYSPKKIENYVQEFWKKNKTFEVKEDPKKEKYYCLPMLPYPSGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMGWD 80
Cdd:COG0495 1 MQERYNPKEIEKKWQKYWEENGTFKADEDSSKPKYYVLDMFPYPSGRLHMGHVRNYTIGDVVARYKRMQGYNVLHPMGWD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 81 AFGLPAEEAAIRNNTDPFSWTQKNIKYMKKQLQSLGFSYDWSREITTCHPEYYHWEQWFFTKLYEKKLVYKKNSLVNWCS 160
Cdd:COG0495 81 AFGLPAENAAIKNGVHPAEWTYENIANMRRQLKRLGLSYDWSREIATCDPEYYKWTQWIFLQLYEKGLAYRKEAPVNWCP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 161 YDKTVLANEQVIDGCCWRCQNKIRIKQIPQWFIKIRNYAESLYQDLKKLTHWPENVKNMQRNWIGRIKGFEITLNVFNTC 240
Cdd:COG0495 161 VDQTVLANEQVIDGRCWRCGAPVEKKELPQWFLKITDYADELLDDLDKLDGWPEKVKTMQRNWIGRSEGAEVDFPVEGSD 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 241 QKLKVFTQRLDLLMGVTYISISSCHKLSINL--SKKNELIKKFIKKYRYIS----QEEQyKVKyTGINTNLFVVHPITKK 314
Cdd:COG0495 241 EKITVFTTRPDTLFGATFMVLAPEHPLVKELatPEQNAAVAAFIEEAKKKSeierTSET-KEK-TGVFTGLYAINPLTGE 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 315 TIPIWISNATHIEYGTNAVLSIPGHNENDWNFAVKNNLKIKYVIFNPDHQEPKLYTSFLDIKGTLFNSQEFNGLNLKDGT 394
Cdd:COG0495 319 KIPIWIADYVLMDYGTGAVMAVPAHDQRDFEFAKKYGLPIKQVIAPEDGDDPDILEEAYTGDGVLINSGEFDGLDSEEAK 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 395 EKIKKILYKKKILKEKINYKLQDWCISRQRYWGTPIPMAKFKNGKMIPIPENQLPVVLPKI----RKNTNLLQQAinfnS 470
Cdd:COG0495 399 EAIIEWLEEKGLGKRKVNYRLRDWLISRQRYWGEPIPIIHCEDCGVVPVPEDQLPVELPEDvdfdPTGGSPLARA----P 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 471 KWAEIF--IHGKHAIREIDTFDTFMESSWYYARYTCPNFNTGMIDSIASKYWLPVDQYIGGIEHAIMHLMYFRFYHKLLR 548
Cdd:COG0495 475 EWVNVTcpKCGGPARRETDTMDTFVDSSWYYLRYTDPHNDEAPFDPEAANYWLPVDQYIGGIEHAILHLLYARFFTKVLR 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 549 DFKLVDFDEPVKNLLCQGMVLseafykidsnsqrkwfnsssvlikrntkgEIIESHtqkgekLIYAGMIKMSKSKNNGIE 628
Cdd:COG0495 555 DLGLVSFDEPFKRLLTQGMVL-----------------------------EVGKDG------VVIGGIEKMSKSKGNVVD 599
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 629 PELIIQRYGADTIRLFIMFSAPVESDLEWKESGLKGIYRFLKKLWMLIFNYIDikntHKKINFDFLNHQQSELRYQLHKT 708
Cdd:COG0495 600 PDEIIEKYGADTLRLFEMFAGPPERDLEWSDSGVEGAYRFLNRVWRLVVDEAE----ALKLDVADLSEADKELRRALHKT 675
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 709 IAKVSDDIGrRQTFNTAISEIMKLVNQLSKAPIKEEQDKSIMRESLICIIKMLYPFTPHFCFFVWNYFNNHSSIDNEKWP 788
Cdd:COG0495 676 IKKVTEDIE-RLRFNTAIAALMELVNALYKAKDSGEADRAVLREALETLVLLLAPFAPHIAEELWERLGHEGSVADAPWP 754
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|...
gi 11134968 789 IFQKDILSKKYSTIVAQINGKKRCATKISDSLTKEEIFLYIQNQPIIKKYLED 841
Cdd:COG0495 755 EADEAALVEDEVTIVVQVNGKVRGKIEVPADASKEELEAAALADEKVQKFLEG 807
|
|
| leuS_bact |
TIGR00396 |
leucyl-tRNA synthetase, eubacterial and mitochondrial family; The leucyl-tRNA synthetases ... |
5-842 |
0e+00 |
|
leucyl-tRNA synthetase, eubacterial and mitochondrial family; The leucyl-tRNA synthetases belong to two families so broadly different that they are represented by separate models. This model includes both eubacterial and mitochondrial leucyl-tRNA synthetases. It generates higher scores for some valyl-tRNA synthetases than for any archaeal or eukaryotic cytosolic leucyl-tRNA synthetase. Note that the enzyme from Aquifex aeolicus is split into alpha and beta chains; neither chain is long enough to score above the trusted cutoff, but the alpha chain scores well above the noise cutoff. The beta chain must be found by a model and search designed for partial length matches. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273057 [Multi-domain] Cd Length: 842 Bit Score: 966.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 5 YSPKKIENYVQEFWKKNKTFEVKEDPKKEKYYCLPMLPYPSGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMGWDAFGL 84
Cdd:TIGR00396 1 YNHIEIEEKWQQKWDENKTFKVTDDSSKPKYYILSMFPYPSGALHMGHVRNYTITDVLSRYYRMKGYNVLHPIGWDAFGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 85 PAEEAAIRNNTDPFSWTQKNIKYMKKQLQSLGFSYDWSREITTCHPEYYHWEQWFFTKLYEKKLVYKKNSLVNWCSYDKT 164
Cdd:TIGR00396 81 PAENAAIKRGIHPAKWTYENIANMKKQLQALGFSYDWDREIATCDPEYYKWTQWIFLELFEKGLAYVKEADVNWCPNDGT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 165 VLANEQVI-DGCCWRCQNKIRIKQIPQWFIKIRNYAESLYQDLKKLTHWPENVKNMQRNWIGRIKGFEITLNVFNTCQKL 243
Cdd:TIGR00396 161 VLANEQVDsDGRSWRGDTPVEKKELKQWFLKITAYAEELLNDLEELDHWPESVKEMQRNWIGKSEGVEITFKIADHDEKI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 244 KVFTQRLDLLMGVTYISISSCHKLSINLSKKNELIKKFIKKYRYISQEEQYKVK--YTGINTNLFVVHPITKKTIPIWIS 321
Cdd:TIGR00396 241 TVFTTRPDTIFGVTYLALAPEHPLVEKAAENNPKVAAFIKKILNKTVAERTKATkeKKGVDTGIKAIHPLTGEKIPIWVA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 322 NATHIEYGTNAVLSIPGHNENDWNFAVKNNLKIKYVIFNPDHQEPKlyTSFLDIKGTLFNSQEFNGLNLKDGTEKIKKIL 401
Cdd:TIGR00396 321 NYVLMEYGTGAVMGVPAHDERDFEFAQKYGLPIKPVIDPAEKDLSL--TAAYTEDGVLVNSGEFNGLNSSEARNAIIDML 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 402 YKKKILKEKINYKLQDWCISRQRYWGTPIPMAKFKNGKMIPIPENQLPVVLPKIRKNTNLLQQAINFNSKWAEIFI--HG 479
Cdd:TIGR00396 399 EKEGKGKRKVNYRLRDWGFSRQRYWGEPIPIIHCEDGGVVPVPEEDLPVILPEDVVYDGDGGSPLSRIPEWVNVTCpsCG 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 480 KHAIREIDTFDTFMESSWYYARYTCPNFNTGMIDSIASKYWLPVDQYIGGIEHAIMHLMYFRFYHKLLRDFKLVDFDEPV 559
Cdd:TIGR00396 479 KPALRETDTMDTFAGSSWYYLRYLDPKNTDGPFDKEKAEYWLPVDLYIGGIEHAILHLLYARFFHKFLRDIGYVNTKEPF 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 560 KNLLCQGMVLseAFYKIDSNSQRkwfnsSSVLIKRNTKGEIIESHtqkgeKLIYAGMIKMSKSKNNGIEPELIIQRYGAD 639
Cdd:TIGR00396 559 KKLINQGMVL--GFYYPPNGKVP-----ADVLTERDEKGKDKAGG-----ELVYVGYEKMSKSKGNGIDPQEIVESYGAD 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 640 TIRLFIMFSAPVESDLEWKESGLKGIYRFLKKLWMLIFNYIDIKNTHKKINFDfLNHQQSELRYQLHKTIAKVSDDIGRR 719
Cdd:TIGR00396 627 ALRLFIMFMGPIAASLEWNESGLEGARRFLDRVWNLVYEITGELDAASLTVTA-LEEAQKELRRDVHKFLKKVTEDLEKR 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 720 QTFNTAISEIMKLVNQLSKAPikeeqDKSIMRESLICIIKMLYPFTPHFCFFVWNYFN-NHSSIDNEKWPIFQKDILSKK 798
Cdd:TIGR00396 706 ESFNTAISAMMELLNKLYKAK-----KEALMLEYLKGFVTVLSPFAPHLAEELWEKLGsEPFIIDNAKWPVVDETALVED 780
|
810 820 830 840
....*....|....*....|....*....|....*....|....
gi 11134968 799 YSTIVAQINGKKRCATKISDSLTKEEIFLYIQNQPIIKKYLEDV 842
Cdd:TIGR00396 781 KTLIVVQVNGKFRAKITVPKDADEEQVEELAKQDPEVKKYLENK 824
|
|
| PLN02563 |
PLN02563 |
aminoacyl-tRNA ligase |
5-841 |
0e+00 |
|
aminoacyl-tRNA ligase
Pssm-ID: 178177 [Multi-domain] Cd Length: 963 Bit Score: 651.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 5 YSPKKIENYVQEFWKKNKTFEVKE--DPKKEKYYCLPMLPYPSGK-LHMGHVRNYTISDVISRYQRMLGKNVLQPMGWDA 81
Cdd:PLN02563 80 YPFHEIEPKWQRYWEENRTFRTPDdvDTSKPKFYVLDMFPYPSGAgLHVGHPEGYTATDILARYKRMQGYNVLHPMGWDA 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 82 FGLPAEEAAIRNNTDPFSWTQKNIKYMKKQLQSLGFSYDWSREITTCHPEYYHWEQWFFTKLYEKKLVYKKNSLVNWCSY 161
Cdd:PLN02563 160 FGLPAEQYAIETGTHPKITTLKNIARFRSQLKSLGFSYDWDREISTTEPEYYKWTQWIFLQLLKRGLAYQAEVPVNWCPA 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 162 DKTVLANEQVIDGCCWRCQNKIRIKQIPQWFIKIRNYAESLYQDLKKLtHWPENVKNMQRNWIGRIKGFEITLNVFN--- 238
Cdd:PLN02563 240 LGTVLANEEVVDGLSERGGHPVIRKPMRQWMLKITAYADRLLEDLDDL-DWPESIKEMQRNWIGRSEGAELDFSVLDgeg 318
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 239 --TCQKLKVFTQRLDLLMGVTYISISSCHKLSINLSKKNEliKKFIKKYRYIS-------QEEQYKVKyTGINTNLFVVH 309
Cdd:PLN02563 319 keRDEKITVYTTRPDTLFGATYLVVAPEHPLLSSLTTAEQ--KEAVEEYVDAAsrksdleRTELQKEK-TGVFTGSYAIN 395
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 310 PITKKTIPIWISNATHIEYGTNAVLSIPGHNENDWNFAVKNNLKIKYVIFNPDHQEP---KLYTSfldiKGTLFNSQE-- 384
Cdd:PLN02563 396 PATGEAIPIWVADYVLGSYGTGAIMAVPAHDTRDFEFAQKFDLPIKWVVKPADGNEDdaeKAYTG----EGVIVNSSSsg 471
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 385 --FNGLNLKDGTEKIKKILYKKKILKEKINYKLQDWCISRQRYWGTPIPMAKFKN-GKMIPIPENQLPVVLPKIRKNT-- 459
Cdd:PLN02563 472 ldINGLSSKEAAKKVIEWLEETGNGKKKVNYKLRDWLFARQRYWGEPIPVVFLEDsGEPVPVPESDLPLTLPELDDFTpt 551
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 460 ----NLLQQAINfnskWAEIF--IHGKHAIREIDTFDTFMESSWYYARYTCPNFNTGMIDSIASKYWLPVDQYIGGIEHA 533
Cdd:PLN02563 552 gtgePPLAKAVS----WVNTVdpSSGKPARRETNTMPQWAGSCWYYLRFMDPKNSNALVDKEKEKYWMPVDLYVGGAEHA 627
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 534 IMHLMYFRFYHKLLRDFKLVDFDEPVKNLLCQGMVLSEAFYKIDSNSQRKWFNSSSVLIKRNTKGEII--ESHTQKGEKL 611
Cdd:PLN02563 628 VLHLLYARFWHKVLYDIGVVSTKEPFQCLVNQGMILGEVEYTAFKDSDGEYVSADTADRLGELQQEKIpeEKVIKSGDSF 707
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 612 I---------YAGMIKMSKSKNNGIEPELIIQRYGADTIRLFIMFSAPVESDLEWKESGLKGIYRFLKKLWMLIFNYIDI 682
Cdd:PLN02563 708 VlkddpsirlIARAHKMSKSRGNVVNPDDVVSEYGADSLRLYEMFMGPLRDSKTWSTSGVEGVHRFLGRTWRLVVGAPLP 787
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 683 KNTHKKINFDFLNHQQSELRYQLHKTIAKVSDDI-GRRqtFNTAISEIMKLVNQLSKapiKEEQDKSIMREslicIIKML 761
Cdd:PLN02563 788 DGSFRDGTVVTDEEPSLEQLRLLHKCIAKVTEEIeSTR--FNTAISAMMEFTNAAYK---WDKVPREAIEP----FVLLL 858
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 762 YPFTPHFCFFVWNYFNNHSSIDNEKWPIFQKDILSKKYSTIVAQINGKKRCATKISDSLTKEEIFLYIQNQPIIKKYLED 841
Cdd:PLN02563 859 SPYAPHLAEELWFRLGHSNSLAYEPWPEANPSYLVDDTVVLPVQINGKTRGTIEVEEGCSEDDAFALASQDEKLSKYLDG 938
|
|
| LeuRS_core |
cd00812 |
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic ... |
34-657 |
5.55e-108 |
|
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. In Aquifex aeolicus, the gene encoding LeuRS is split in two, just before the KMSKS motif. Consequently, LeuRS is a heterodimer, which likely superimposes with the LeuRS monomer found in most other organisms. LeuRS has an insertion in the core domain, which is subject to both deletions and rearrangements and thus differs between prokaryotic LeuRS and archaeal/eukaryotic LeuRS. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173906 [Multi-domain] Cd Length: 314 Bit Score: 334.60 E-value: 5.55e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 34 KYYCLPMLPYPSGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMGWDAFGLPAEEAAIRNNTDPFSWTQKNIKYMKKQLQ 113
Cdd:cd00812 1 KFYILVMFPYPSGALHVGHVRTYTIGDIIARYKRMQGYNVLFPMGFDAFGLPAENAAIKIGRDPEDWTEYNIKKMKEQLK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 114 SLGFSYDWSREITTCHPEYYHWEQWFFTKLYEKKLVYKKNSLVNWCsydktvlaneqvidgccwrcqnkiriKQIPQWFI 193
Cdd:cd00812 81 RMGFSYDWRREFTTCDPEYYKFTQWLFLKLYEKGLAYKKEAPVNWC--------------------------KLLDQWFL 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 194 KIRN--YAESLYQDLKKLTHWPenvknmqrnwigrikgfEITLNVFNTcqklkvftqrldllmgvtyisisschklsinl 271
Cdd:cd00812 135 KYSEteWKEKLLKDLEKLDGWP-----------------EEVRAMQEN-------------------------------- 165
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 272 skknelikkfikkyryisqeeqykvkytgintnlfvvhpitkktipiWISnathieygtnavlsipghnendwnfavknn 351
Cdd:cd00812 166 -----------------------------------------------WIG------------------------------ 168
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 352 lkikyvifnpdhqepklytsfldikgtlfnsqefnglnlkdgtekikkilykkkilkekinyklqdwcISRQRYWGTPIP 431
Cdd:cd00812 169 --------------------------------------------------------------------CSRQRYWGTPIP 180
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 432 MAkfkngkmipipenqlpvvlpkirkntnllqqainfnskwaeifihgkhaireiDTFDTFMESSWYYARYTCPNFNTGM 511
Cdd:cd00812 181 WT-----------------------------------------------------DTMESLSDSTWYYARYTDAHNLEQP 207
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 512 IDSIAS------KYWLPVDQYIGGIEHAIMHLMYFRFYHKLLRDFKLVdFDEPVKNLLCQGMVLSEafykidsnsqrkwf 585
Cdd:cd00812 208 YEGDLEfdreefEYWYPVDIYIGGKEHAPNHLLYSRFNHKALFDEGLV-TDEPPKGLIVQGMVLLE-------------- 272
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 11134968 586 nsssvlikrntkGEiieshtqkgekliyagmiKMSKSKNNGIEPELIIQRYGADTIRLFIMFSAPVESDLEW 657
Cdd:cd00812 273 ------------GE------------------KMSKSKGNVVTPDEAIKKYGADAARLYILFAAPPDADFDW 314
|
|
| tRNA-synt_1_2 |
pfam13603 |
Leucyl-tRNA synthetase, Domain 2; This is a family of the conserved region of Leucine-tRNA ... |
221-395 |
7.62e-74 |
|
Leucyl-tRNA synthetase, Domain 2; This is a family of the conserved region of Leucine-tRNA ligase or Leucyl-tRNA synthetase, EC:6.1.1.4.
Pssm-ID: 433342 [Multi-domain] Cd Length: 185 Bit Score: 239.37 E-value: 7.62e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 221 RNWIGRIKGFEITLNVFNTCQKLKVFTQRLDLLMGVTYISISSCHKLSINLSKKNELIKKFIKKYRYISQEEQYKVK--Y 298
Cdd:pfam13603 1 RNWIGRSEGAEITFPVEGTDEKIEVFTTRPDTLMGVTFVALAPEHPLVEKLAEKNPEVAAFIEECKNTSEIERTSETkeK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 299 TGINTNLFVVHPITKKTIPIWISNATHIEYGTNAVLSIPGHNENDWNFAVKNNLKIKYVIFNPDHQE-PKLYTSFLDIKG 377
Cdd:pfam13603 81 EGVFTGLYAIHPITGEKIPIWIANFVLMEYGTGAVMAVPAHDQRDFEFAKKYNLPIKPVIQPEDGDLdLDIMTEAYTEEG 160
|
170
....*....|....*...
gi 11134968 378 TLFNSQEFNGLNLKDGTE 395
Cdd:pfam13603 161 ILVNSGEFDGLDSEEAKE 178
|
|
| valS |
TIGR00422 |
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase ... |
1-842 |
1.59e-65 |
|
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase and is particularly closely related to the isoleucyl tRNA synthetase. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273070 [Multi-domain] Cd Length: 861 Bit Score: 235.72 E-value: 1.59e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 1 MEKEYSPKKIENYVQEFWKKNKTFEVKEDPKKEKYyCLPMLP-YPSGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMGW 79
Cdd:TIGR00422 1 MPKDYDPHEVEKKWYKKWEKSGFFKPDGNSNKPPF-CIDIPPpNVTGSLHIGHALNWSIQDIIARYKRMKGYNVLWLPGT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 80 DAFGLPAE-----EAAIRNNT------DPFS-----WTQKNIKYMKKQLQSLGFSYDWSREITTCHPEYYHWEQWFFTKL 143
Cdd:TIGR00422 80 DHAGIATQvkvekKLGAEGKTkhdlgrEEFRekiweWKEESGGTIKNQIKRLGASLDWSRERFTMDEGLSKAVKEAFVRL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 144 YEKKLVYKKNSLVNWCSYDKTVLANEQVIdgccwrcqnkirikqipqwfikirnyaeslYQDLK-KLTHWPENVKNmqrn 222
Cdd:TIGR00422 160 YEKGLIYRGEYLVNWDPKLNTAISDIEVE------------------------------YKEVKgKLYYIRYPLAN---- 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 223 wigrikgfeitlnvfNTCQKLKVFTQRLDLLMGVTYISISSchklsinlskKNELIKKFIKKyryisqeeqykvkytgin 302
Cdd:TIGR00422 206 ---------------GSKDYLVVATTRPETMFGDTAVAVHP----------EDERYKHLIGK------------------ 242
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 303 tnlFVVHPITKKTIPIWISNATHIEYGTNAVLSIPGHNENDWNFAVKNNLKIKYVI-----FN----------------- 360
Cdd:TIGR00422 243 ---KVILPLTGRKIPIIADEYVDMEFGTGAVKVTPAHDFNDYEWGKRHNLEFINILdedglLNenagkyqgltrfearkk 319
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 361 --PDHQEPKLYTSFLDIKGTL------------------FNSQEFNGLNLKDGTEKIKKILYKKKILKEKINY--KLQDW 418
Cdd:TIGR00422 320 ivEDLKEEGLLVKIEPHTHNVgtcwrsgtvvepllskqwFVKVEKLADKALEAAEEGEIKFVPKRMEKRYLNWlrNIKDW 399
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 419 CISRQRYWGTPIPMAKFKNGKMIPIPENQLPVVLPKIRKNTNLLQQainfnskwaeifihgkhairEIDTFDTFMESS-W 497
Cdd:TIGR00422 400 CISRQLIWGHRIPVWYCKECGEVYVAKEEPLPDDKTNTGPSVELEQ--------------------DTDVLDTWFSSSlW 459
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 498 YYARYTCPNFNTGMidsiasKYWLPVDQYIGGieHAIMHLMYFRFyhkLLRDFKLVDfDEPVKNLLCQGMVlseafykid 577
Cdd:TIGR00422 460 PFSTLGWPDETKDL------KKFYPTDLLVTG--YDIIFFWVARM---IFRSLALTG-QVPFKEVYIHGLV--------- 518
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 578 snsqrkwfnsssvlikRNTKGEiieshtqkgekliyagmiKMSKSKNNGIEPELIIQRYGADTIRLFIMFSAPVESDLEW 657
Cdd:TIGR00422 519 ----------------RDEQGR------------------KMSKSLGNVIDPLDVIEKYGADALRFTLASLVTPGDDINF 564
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 658 KESGLKGIYRFLKKLW-------MLIFNYIDIKNTHKKINFdflnhqqSElRYQLHK---TIAKVSDDIGRRQtFNTAIS 727
Cdd:TIGR00422 565 DWKRVESARNFLNKLWnasrfvlMNLSDDLELSGGEEKLSL-------AD-RWILSKlnrTIKEVRKALDKYR-FAEAAK 635
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 728 ---------------EIMKLVNQlSKAPIKEEQDKSIMRESLICIIKMLYPFTPHFCFFVWNYFNN-HSSIDNEKWPIFQ 791
Cdd:TIGR00422 636 alyefiwndfcdwyiELVKYRLY-NGNEAEKKAARDTLYYVLDKALRLLHPFMPFITEEIWQHFKEgADSIMLQSYPVVD 714
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*....
gi 11134968 792 KDILSKK--------YSTIVAQINGKKRCATKISDSLTKEEIFLYIQNQPIIKKYLEDV 842
Cdd:TIGR00422 715 AEFVDEEaekafellKEIIVSIRNLKAESNIPPNAPLKVLLIYTEAETAERLKLNAVDI 773
|
|
| valS |
PRK13208 |
valyl-tRNA synthetase; Reviewed |
1-842 |
1.67e-49 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 237306 [Multi-domain] Cd Length: 800 Bit Score: 188.09 E-value: 1.67e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 1 MEKEYSPKKIENYVQEFWKKNKTFEVKEDPKKEKYYCLPMLPYPSGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMGWD 80
Cdd:PRK13208 6 LPKKYDPEELEEKWQKIWEEEGTYKFDPDERKPVYSIDTPPPTVSGSLHIGHVFSYTHTDFIARYQRMRGYNVFFPQGWD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 81 AFGLPAE-----EAAIRnnTDPFS----------WTQKNIKYMKKQLQSLGFSYDWSREITTCHPEYYHWEQWFFTKLYE 145
Cdd:PRK13208 86 DNGLPTErkvekYYGIR--KDDISreefielcreLTDEDEKKFRELWRRLGLSVDWSLEYQTISPEYRRISQKSFLDLYK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 146 KKLVYKKNSLVNWCSYDKTVLAneqvidgccwrcqnkirikqipqwfikirnYAESLYQDLKKLTHwpenvknmqrnwig 225
Cdd:PRK13208 164 KGLIYRAEAPVLWCPRCETAIA------------------------------QAEVEYREREGKLN-------------- 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 226 RIKgFEITLNvfntcQKLKVFTQRLDLLmgvtyisiSSCHKLSINlskknelikkfikkyryiSQEEQYKvKYTGintnL 305
Cdd:PRK13208 200 YIK-FPVEDG-----EEIEIATTRPELL--------PACVAVVVH------------------PDDERYK-HLVG----K 242
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 306 FVVHPITKKTIPIWISNATHIEYGTNAVLSIPGHNEND---WNfavKNNLKIKYVIfnpdhqepklytsflDIKGTLF-N 381
Cdd:PRK13208 243 TAIVPLFGVEVPILADPLVDPDFGTGAVMICTFGDKTDvtwWR---ELNLPTRIII---------------DEDGRMTeA 304
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 382 SQEFNGLNLKDGTEK------------------------------------------IKKILYKKKILKEKIN------- 412
Cdd:PRK13208 305 AGKLAGLTIEEARKKivedlksggllgkqepikhnvkfcercdtpleilvtrqwfikVLDLKEELLERGKEINwypehmr 384
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 413 YKLQ--------DWCISRQRYWGTPIPMAKFKN-GKMIPIPENQLPVV----LPKI-----RKNTNLlqqainfnskwae 474
Cdd:PRK13208 385 VRLEnwieglnwDWCISRQRYFGTPIPVWYCKDcGHPILPDEEDLPVDptkdEPPGykcpqCGSPGF------------- 451
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 475 ifihgkhaIREIDTFDTFMESSwyyaryTCPNFNTG-MIDSIASKYWLPVD---QyiGgieHAIMhlmyfRF--YHKLLR 548
Cdd:PRK13208 452 --------EGETDVMDTWATSS------ITPLIVTGwERDEDLFEKVFPMDlrpQ--G---HDII-----RTwlFYTILR 507
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 549 DFKLVDfDEPVKNLLCQGMVLSEafykidsnsqrkwfnsssvlikrntKGEiieshtqkgekliyagmiKMSKSKNNGIE 628
Cdd:PRK13208 508 AYLLTG-KLPWKNIMISGMVLDP-------------------------DGK------------------KMSKSKGNVVT 543
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 629 PELIIQRYGADTIRLFIMfSAPVESDLEWKESGLKGIYRFLKKLW-----MLIFNYIDIKNTHKKIN-FD--FLNhqqse 700
Cdd:PRK13208 544 PEELLEKYGADAVRYWAA-SARLGSDTPFDEKQVKIGRRLLTKLWnasrfVLHFSADPEPDKAEVLEpLDrwILA----- 617
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 701 lryQLHKTIAKVSDDIGRRQtFNTAISEIMK------------LVNQLSKAPIKEEQDKS-------IMRESLiciiKML 761
Cdd:PRK13208 618 ---KLAKVVEKATEALENYD-FAKALEEIESffwhvfcddyleLVKSRAYGEDEEEEQKSarytlytVLDTLL----RLL 689
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 762 YPFTPHFCFFVWNYFNNhSSIDNEKWPIFQKDILSKKYST---IVAQING-----KKRCATKISDSLTKEEIfLYIQNQP 833
Cdd:PRK13208 690 APFLPFITEEVWSWLYG-GSVHRASWPEPDEELIDEEDEElgeLAKEILSavrkyKSEAGLSLNAPLKKVEV-YGPADLE 767
|
....*....
gi 11134968 834 IIKKYLEDV 842
Cdd:PRK13208 768 LLEAAEEDL 776
|
|
| tRNA-synt_1 |
pfam00133 |
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too ... |
14-658 |
1.10e-48 |
|
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too dissimilar to be included.
Pssm-ID: 459685 [Multi-domain] Cd Length: 602 Bit Score: 182.61 E-value: 1.10e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 14 VQEFWKKNKTFE-VKEDPKKEKYYCLPM-LPYPSGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMGWDAFGLPAE---- 87
Cdd:pfam00133 2 IYEFWDEQGYFKpELEKRKGKPSFTIHDgPPNATGSLHIGHALAKTLKDIVIRYKRMKGYYVLWVPGWDHHGLPTEqvve 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 88 -EAAIRNNTDPF------------SWTQKNIKYMKKQLQSLGFSYDWSREITTCHPEYYHWEQWFFTKLYEKKLVYKKNS 154
Cdd:pfam00133 82 kKLGIKEKKTRHkygreefrekcrEWKMEYADEIRKQFRRLGRSIDWDREYFTMDPELEAAVWEVFVRLHDKGLIYRGKK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 155 LVNWCSYDKTVLANeqvidgccwrcqnkirikqipqwfikirnyAESLYQDLKK-LTHWPENVKNmqrnwigrikgfeit 233
Cdd:pfam00133 162 LVNWSPALNTALSN------------------------------LEVEYKDVKGpSIHVAFPLAD--------------- 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 234 lnvfNTCQKLKVFTQRLDLLMGVTYISISSCHKLSIN---LSKKNELIKKFIKKYRYISQEEQYKVKYTginTNLFVVHP 310
Cdd:pfam00133 197 ----DEGASLVIWTTTPWTLPGNTAVAVNPEFDYVITgegYILAEALLKSLYKKGTDKKILEDFRGKEL---EGKEAIHP 269
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 311 ITKKTIPIWISNATHIEYGTNAVLSIPGHNENDWNFAVKNNLKIKYVI-----FNPDHQE---------PKLYTSFLDIK 376
Cdd:pfam00133 270 FVNREIPIITDDYVDMEFGTGAVHIAPAHGENDYEVGQRHNLEVINPVdddgtFTEEAPDfqgvyrfdaRKKIVELLTEK 349
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 377 GTLFNSQEFN---GLNLKDGTE-----------KIKKILYKKKILKEKINYK--------------LQDWCISRQRYWGT 428
Cdd:pfam00133 350 GLLLKIEPFThsyPFCWRSGTPiipratpqwfvRMDELADQALEAVEKVQFVpksgekryfnwlanIQDWCISRQRWWGH 429
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 429 PIPMAKFKNGK-MIPIPENQLPVVLP--KIRKNTNLLQQAInfnskwaEIFIHGKHAIREI-DTFDTFMES-SWYYARYT 503
Cdd:pfam00133 430 PIPAWVSKDTEeVVCRGELFELVAGRfeEEGSIKWLHREAK-------DKLGYGKGTLEQDeDVLDTWFSSgSWPFSTLG 502
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 504 CPNFNTGmidsiASKYWLPVDQYIGGIEhaimhLMYFRFYHKLLRDFKLVDfDEPVKNLLCQGMVLseafykiDSNSQrk 583
Cdd:pfam00133 503 WPFVNTE-----EFKKFFPADMLLEGSD-----QTRGWFYRMIMLSTALTG-SVPFKNVLVHGLVR-------DEQGR-- 562
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 11134968 584 wfnsssvlikrntkgeiieshtqkgekliyagmiKMSKSKNNGIEPELIIQRYGADTIRLFIMfSAPVESDLEWK 658
Cdd:pfam00133 563 ----------------------------------KMSKSLGNVIDPLDVIDKYGADALRLWLA-NSDYGRDINLS 602
|
|
| ValRS_core |
cd00817 |
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) ... |
42-228 |
2.51e-46 |
|
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) catalytic core domain. This enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. ValRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 185677 [Multi-domain] Cd Length: 382 Bit Score: 170.51 E-value: 2.51e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 42 PYPSGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMGWDAFGLPAE---------EAAIRNNTDP-------FSWTQKNI 105
Cdd:cd00817 10 PNVTGSLHMGHALNNTIQDIIARYKRMKGYNVLWPPGTDHAGIATQvvvekklgiEGKTRHDLGReeflekcWEWKEESG 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 106 KYMKKQLQSLGFSYDWSREITTCHPEYYHWEQWFFTKLYEKKLVYKKNSLVNWCSYDKTVLANEQVidgcCWRCQNKIRI 185
Cdd:cd00817 90 GKIREQLKRLGASVDWSREYFTMDPGLSRAVQEAFVRLYEKGLIYRDNRLVNWCPKLRTAISDIEV----CSRSGDVIEP 165
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 11134968 186 KQIPQWFIKIRNYAESLYQDLKK--LTHWPENVKNMQRNWIGRIK 228
Cdd:cd00817 166 LLKPQWFVKVKDLAKKALEAVKEgdIKFVPERMEKRYENWLENIR 210
|
|
| Anticodon_Ia_Leu_BEm |
cd07958 |
Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; ... |
657-774 |
2.32e-40 |
|
Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; This domain is found in leucyl tRNA synthetases (LeuRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain. In contrast to other class Ia enzymes, the anticodon is not used as an identity element in LeuRS (with exceptions such as Saccharomyces cerevisiae and some other eukaryotes). No anticodon-binding site can be defined for this family, which includes bacterial and eukaryotic mitochondrial members, as well as LeuRS from the archaeal Halobacteria. LeuRS catalyzes the transfer of leucine to the 3'-end of its tRNA.
Pssm-ID: 153412 [Multi-domain] Cd Length: 117 Bit Score: 144.28 E-value: 2.32e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 657 WKESGLKGIYRFLKKLWMLIFNYIDIKNTHKkiNFDFLNHQQSELRYQLHKTIAKVSDDIGRRQtFNTAISEIMKLVNQL 736
Cdd:cd07958 1 WSDSGVEGAYRFLNRVWRLVTELAEALAAPA--AAAELSEEDKELRRKLHKTIKKVTEDIERLR-FNTAIAALMELVNAL 77
|
90 100 110
....*....|....*....|....*....|....*...
gi 11134968 737 SKAPIKEEQDKSIMRESLICIIKMLYPFTPHFCFFVWN 774
Cdd:cd07958 78 YKYKKKDAQHAAVLREALETLVLLLAPFAPHIAEELWE 115
|
|
| ileS |
TIGR00392 |
isoleucyl-tRNA synthetase; The isoleucyl tRNA synthetase (IleS) is a class I amino acyl-tRNA ... |
2-822 |
7.76e-40 |
|
isoleucyl-tRNA synthetase; The isoleucyl tRNA synthetase (IleS) is a class I amino acyl-tRNA ligase and is particularly closely related to the valyl tRNA synthetase. This model may recognize IleS from every species, including eukaryotic cytosolic and mitochondrial forms. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273054 [Multi-domain] Cd Length: 861 Bit Score: 158.69 E-value: 7.76e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 2 EKEYSPKKIENYVQEFWKKNKTFE-VKEDPKKEKYYCL---PmlPYPSGKLHMGHVRNYTISDVISRYQRMLGKNVLQPM 77
Cdd:TIGR00392 3 PMRGNLSKREEKILAFWQENDIFEkVKKLNKGKPEFIFhdgP--PYANGSIHLGHALNKILKDIILRYKTMQGFNVTRKP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 78 GWDAFGLPAEEAA-----IRNNTDPFSWT------------QKNIKYMKKQLQSLGFSYDWSREITTCHPEYYHWEQWFF 140
Cdd:TIGR00392 81 GWDTHGLPIEHKVekklgISGKKEISSLEieefrekcrefaLKQIEEQREQFQRLGVWGDWENPYKTMDPSYEESQWWLF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 141 TKLYEKKLVYKKNSLVNWCSYDKTVLANEQVIDGCCWRCQNKIRIkqipqwFIKIRNYAESLYQDLKKL--------THW 212
Cdd:TIGR00392 161 KEAHEKGLLYRGLKPVYWSPRCRTALAEAEVEYKENYKDVKDPSI------YVKFPVKKDKKTYLKVKLsslliwttTPW 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 213 --PENVKnmqrnwigrikgfeITLNVFNTCQKLKVFTQRLDLLMGVtyisiSSCHKLSINLSKKNELIKKFikkyryiSQ 290
Cdd:TIGR00392 235 tlPSNLA--------------IAVHPDFEYALVQDNTKVEYFILAK-----KLVEKLYNKAGSDYEIIKTF-------KG 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 291 EEQYKVKYTGIntnLFVVHPITKKTIPIWISnATHI--EYGTNAVLSIPGHNENDWNFAVKNNLKIkyviFNPDHQEPKL 368
Cdd:TIGR00392 289 SDLEGLEYEHP---LYDFVSQLKEGAPVVIG-GDHVttEDGTGIVHTAPGHGEEDYEIGKKYGLEV----LSPVDEKGVY 360
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 369 YTSFLDIKGTLFnsqEFNGLNLKDGTEKIKKILYKKKI------------------------------------------ 406
Cdd:TIGR00392 361 TEGVNDFQGRFV---KDADKDIIKANKIIIEQLKDKGLllkaekithsyphcwrtktpviyrateqwfiktkdikdqmle 437
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 407 LKEKINYK--------------LQDWCISRQRYWGTPIPMAKFKNGkmipiPEnqlPVVLPKIRKNTNLLQQAiNFNSKW 472
Cdd:TIGR00392 438 QIKKVNWVpewgegrfgnwlenRPDWCISRQRYWGIPIPIWYCEDT-----GE---PIVVGSIEELIELIELK-GIDAWF 508
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 473 A--------EIFIH---GKHAIREIDTFDTFMES-SWYYARYTCPNFNtgmidsIASKYWLPVDQYIGGIEHaimhlmyF 540
Cdd:TIGR00392 509 EdlhrdfldKITLKsgdGGEYRRVPDVLDVWFDSgSMPYASIHYPFEN------EKFKEVFPADFILEGSDQ-------T 575
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 541 R--FYHKLLrdFKLVDFDE-PVKNLLCQGMVLSEafykidsnsqrkwfnsssvlikrntKGEiieshtqkgekliyagmi 617
Cdd:TIGR00392 576 RgwFYSSLA--IGTALFGQaPYKNVITHGFTLDE-------------------------KGR------------------ 610
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 618 KMSKSKNNGIEPELIIQRYGADTIRLFIMFSAPVEsDLEWKESGLKGIYRFLKKLWMLIFNYIDIKNTHKKINFDFLN-- 695
Cdd:TIGR00392 611 KMSKSLGNVVDPLKVINKYGADILRLYVASSDPWE-DLRFSDEILKQVVEKYRKIRWNTYRFLLTYANLDKFDPLFNSva 689
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 696 -HQQSEL-RYQLHKT---IAKVSDDIGRRQtFNTAISEIM-KLVNQLS-------KAPIKEEQDKS-------IMRESLI 755
Cdd:TIGR00392 690 vEKFPEEdRWILSRLnslVEEVNEALEKYN-FHKVLRALQdFIVEELSnwyiriiRDRLYCEAKDNdkraaqtTLYYALL 768
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 11134968 756 CIIKMLYPFTPHFCFFVWnyfnNHSSIDNEKWPIFQKDILSKKYSTIVAQINGKKRCATKISDSLTK 822
Cdd:TIGR00392 769 TLVRLLAPFLPHTAEEIY----QNLPGGEEEESVHLNLWPEVDEEFIDEALEANMAIVREIVEAFLA 831
|
|
| Ile_Leu_Val_MetRS_core |
cd00668 |
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic ... |
34-224 |
2.02e-33 |
|
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases. These class I enzymes are all monomers. However, in some species, MetRS functions as a homodimer, as a result of an additional C-terminal domain. These enzymes aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. Enzymes in this subfamily share an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids. MetRS has a significantly shorter insertion, which lacks the editing function.
Pssm-ID: 185674 [Multi-domain] Cd Length: 312 Bit Score: 131.00 E-value: 2.02e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 34 KYYCLPMLPYPSGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMGWDAFGLPAEEAA-------------IRNNTDPFSW 100
Cdd:cd00668 1 KFYVTTPPPYANGSLHLGHALTHIIADFIARYKRMRGYEVPFLPGWDTHGLPIELKAerkggrkkktiwiEEFREDPKEF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 101 TQKNIKYMKKQLQSLGFSYDWSREITTCHPEYYHWEQWFFTKLYEKKLVYKknslvnwcsydktvlaneqvidgccwrcq 180
Cdd:cd00668 81 VEEMSGEHKEDFRRLGISYDWSDEYITTEPEYSKAVELIFSRLYEKGLIYR----------------------------- 131
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 11134968 181 NKIRIKQIPQWFIKIRNYAESLYQDLKKLTHWPENVKNMQRNWI 224
Cdd:cd00668 132 GTHPVRITEQWFFDMPKFKEKLLKALRRGKIVPEHVKNRMEAWL 175
|
|
| IleS |
COG0060 |
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA ... |
5-788 |
7.66e-31 |
|
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439830 [Multi-domain] Cd Length: 931 Bit Score: 130.59 E-value: 7.66e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 5 YSPKKIENYVQEFWKKNKTFE--VKEDPKKEKYYcL---PmlPYPSGKLHMGHVRNYTISDVISRYQRMLGKNVL-QPmG 78
Cdd:COG0060 16 ANLPKREPEILKFWEENDIYEksREARAGRPKFV-LhdgP--PYANGDIHIGHALNKILKDIIVRYKTMRGFDVPyVP-G 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 79 WDAFGLPAEEAAIRNN-----------TDPF-----SWTQKNIKYMKKQLQSLGFSYDWSREITTCHPEYyhwEQ---WF 139
Cdd:COG0060 92 WDCHGLPIELKVEKELgikkkdiekvgIAEFrekcrEYALKYVDEQREDFKRLGVWGDWDNPYLTMDPEY---EEsiwWA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 140 FTKLYEKKLVYKKNSLVNWCSYDKTVLANeqvidgccwrcqnkirikqipqwfikirnyAESLYQDLK------------ 207
Cdd:COG0060 169 LKKLYEKGLLYKGLKPVPWCPRCGTALAE------------------------------AEVEYKDVTspsiyvkfpvkd 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 208 -KLTHWPENVKnmqrnwigrikgFEI------TL--NV---FN---TCQKLKVFTqrldllmGVTYIsisschklsinLS 272
Cdd:COG0060 219 eKALLLLEDAY------------LVIwtttpwTLpaNLavaVHpdiDYVLVEVTG-------GERLI-----------LA 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 273 KknELIKKFIKKYRYisqeEQYKVKYT-------GIN-TNLFVVHPITKKTIPIWIsnATHI--EYGTNAVLSIPGHNEN 342
Cdd:COG0060 269 E--ALVEAVLKELGI----EDYEVLATfkgaeleGLRyEHPFYYVVGYDRAHPVIL--GDYVttEDGTGIVHTAPGHGED 340
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 343 DWNFAVKNNLKI--------KYV----------IFNPDhqepKLYTSFLDIKGTLFNSQEF-----------NGL----- 388
Cdd:COG0060 341 DFEVGKKYGLPVlnpvdddgRFTeeaplfaglfVKDAN----PAIIEDLKERGALLAREKIthsyphcwrckTPLiyrat 416
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 389 --------NLKDgtekikkilyKKKILKEKINYK--------------LQDWCISRQRYWGTPIPMakFKNgkmipipen 446
Cdd:COG0060 417 pqwfismdKLRD----------RALEAIEKVNWIpewgegrfgnmlenRPDWCISRQRYWGVPIPI--WVC--------- 475
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 447 qlpvvlpkirKNTNLLQQAINFNSKWAEIFI-HGKHAIREIDTFDTFMEsswyyARYTCPNFNTGM----------IDSI 515
Cdd:COG0060 476 ----------EDCGELHRTEEVIGSVAELLEeEGADAWFELDLHRPFLD-----ETLKCPKCGGTMrrvpdvldvwFDSG 540
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 516 ASKY---------WLPVDQYIGGI-EHaimhlmyfR--FYHKLL-----RDfklvdfDEPVKNLLCQGMVLSEafykids 578
Cdd:COG0060 541 SMHFavlenreelHFPADFYLEGSdQT--------RgwFYSSLLtstalFG------RAPYKNVLTHGFVLDE------- 599
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 579 nsqrkwfnsssvlikrntKGEiieshtqkgekliyagmiKMSKSKNNGIEPELIIQRYGADTIRLFIMfSAPVESDLEWK 658
Cdd:COG0060 600 ------------------DGR------------------KMSKSLGNVVDPQEVIDKYGADILRLWVA-SSDYWGDLRFS 642
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 659 ESGLKGIYRFLKKLWmlifnyidikNTHKKI-----NFDFLNH-----QQSEL-RYQLHKT---IAKVSDDIGRRQtFNT 724
Cdd:COG0060 643 DEILKEVRDVYRRLR----------NTYRFLlanldDFDPAEDavpyeDLPELdRWILSRLnelIKEVTEAYDNYD-FHR 711
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 725 AISEIMKLVN--------QLSKAPIKEEQDKSIMRES--------LICIIKMLYPFTPHFCFFVWNYF--NNHSSIDNEK 786
Cdd:COG0060 712 AYRALHNFCVedlsnwylDISKDRLYTEAADSLDRRAaqttlyevLETLVRLLAPILPFTAEEIWQNLpgEAEESVHLAD 791
|
..
gi 11134968 787 WP 788
Cdd:COG0060 792 WP 793
|
|
| leuS |
PRK12300 |
leucyl-tRNA synthetase; Reviewed |
48-793 |
2.74e-30 |
|
leucyl-tRNA synthetase; Reviewed
Pssm-ID: 237049 [Multi-domain] Cd Length: 897 Bit Score: 128.83 E-value: 2.74e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 48 LHMGHVRNYTISDVISRYQRMLGKNVLQPMGWDAFGLP----AEeaAIRNN----------------------TDPFSWT 101
Cdd:PRK12300 1 LHVGHGRTYTIGDVIARYKRMRGYNVLFPMAFHVTGTPilgiAE--RIARGdpetielykslygipeeelekfKDPEYIV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 102 QKNIKYMKKQLQSLGFSYDWSREITTCHPEYYHWEQWFFTKLYEKKLVYKKNSLVNWCSYDKTVLANEQVIDGccwrcqn 181
Cdd:PRK12300 79 EYFSEEAKEDMKRIGYSIDWRREFTTTDPEYSKFIEWQFRKLKEKGLIVKGSHPVRYCPNDNNPVGDHDLLDG------- 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 182 kiRIKQIPQW-FIKIRNYaESLYqdlkklthwpenvknmqrnwigrikgfeitlnvfntcqkLKVFTQRLDLLMGVTYIS 260
Cdd:PRK12300 152 --EEPEIVEYtLIKFEES-EDLI---------------------------------------LPAATLRPETIFGVTNLW 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 261 ISSCHKLSInlSKKNEliKKFIkkyryISQEEQYKVKYTGIN------------TNLFVVHPITKKTIPIWISNATHIEY 328
Cdd:PRK12300 190 VNPDATYVK--AEVDG--EKWI-----VSKEAAEKLSFQDRDveiieeikgselIGKKVKNPVTGKEVPILPADFVDPDN 260
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 329 GTNAVLSIPGHNENDW--------NFAVKNNLKIKYVI----------------FNPDHQE-PKL--YTSflDI------ 375
Cdd:PRK12300 261 GTGVVMSVPAHAPYDYvalrdlkkNKELLDVIEPIPLIevegygefpakevvekLGIKSQEdPELeeATK--EVyraefh 338
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 376 KGTLF-NSQEFNGLNLKDGTEKIKKILYKKKI------LKEK--------------------INYK-------------- 414
Cdd:PRK12300 339 KGVLKeNTGEYAGKPVREAREKITKDLIEKGIadimyeFSNRpvycrcgtecvvkvvkdqwfIDYSdpewkelahkaldn 418
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 415 ------------------LQDWCISRQRYWGTPIP----------------MA------KFKNGKMipIPENQLP----- 449
Cdd:PRK12300 419 meiipeeyrkefentidwLKDRACARRRGLGTRLPwdeewiieslsdstiyMAyytiahKIREYGI--KPEQLTPeffdy 496
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 450 VVLPK-----IRKNTNLLQQAInfnskwaeifihgkHAIREidtfdtfmesswyyarytcpNFNtgmidsiaskYWLPVD 524
Cdd:PRK12300 497 VFLGKgdpeeVSKKTGIPKEIL--------------EEMRE--------------------EFL----------YWYPVD 532
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 525 QYIGGIEHAIMHLMYFRFYHKLLrdfklvdFDE---PvKNLLCQGMVLSEafykidsnsqrkwfnsssvlikrntkGEii 601
Cdd:PRK12300 533 WRHSGKDLIPNHLTFFIFNHVAI-------FPEekwP-RGIVVNGFVLLE--------------------------GK-- 576
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 602 eshtqkgekliyagmiKMSKSKNNGIEPELIIQRYGADTIRLFIMFSAPVESDLEWKESGLKGIYRFLKKLWMLIFNYID 681
Cdd:PRK12300 577 ----------------KMSKSKGNVIPLRKAIEEYGADVVRLYLTSSAELLQDADWREKEVESVRRQLERFYELAKELIE 640
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 682 IKnthKKINFDFLNHQqseLRYQLHKTIAKVSDDIGR---RQTFNTAISEIMKLVNQLSKapIKEEQDKSIMRESLICII 758
Cdd:PRK12300 641 IG---GEEELRFIDKW---LLSRLNRIIKETTEAMESfqtRDAVQEAFYELLNDLRWYLR--RVGEANNKVLREVLEIWI 712
|
890 900 910
....*....|....*....|....*....|....*
gi 11134968 759 KMLYPFTPHFCFFVWNYFNNHSSIDNEKWPIFQKD 793
Cdd:PRK12300 713 RLLAPFTPHLAEELWHKLGGEGFVSLEKWPEPDES 747
|
|
| valS |
PRK05729 |
valyl-tRNA synthetase; Reviewed |
1-792 |
2.89e-29 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 235582 [Multi-domain] Cd Length: 874 Bit Score: 125.22 E-value: 2.89e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 1 MEKEYSPKKIENYVQEFWKKNKTFevKEDPKKEKYYCLpMLPYP--SGKLHMGHVRNYTISDVISRYQRMLGKNVL-QP- 76
Cdd:PRK05729 5 LPKTYDPKEVEAKWYQKWEEKGYF--KPDDNSKKPFSI-VIPPPnvTGSLHMGHALNNTLQDILIRYKRMQGYNTLwLPg 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 77 -------------------------MGWDAFglpAEEAairnntdpFSWTQKNIKYMKKQLQSLGFSYDWSREITTCHPE 131
Cdd:PRK05729 82 tdhagiatqmvverqlaaegksrhdLGREKF---LEKV--------WEWKEESGGTITNQLRRLGASCDWSRERFTMDEG 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 132 YYHWEQWFFTKLYEKKLVYKKNSLVNWCSYDKTVLANEQVIDgccwrcqnkiriKQIPQWFIKIRnY--AESlyqdlkkl 209
Cdd:PRK05729 151 LSKAVREVFVRLYEKGLIYRGKRLVNWDPKLQTALSDLEVEY------------KEVKGKLWHIR-YplADG-------- 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 210 thwpenvknmqrnwigriKGFeitlnvfntcqkLKVFTQRLDLLMGVTYISISSchklsinlskKNELIKKFIKKyryis 289
Cdd:PRK05729 210 ------------------SDY------------LVVATTRPETMLGDTAVAVNP----------EDERYKHLIGK----- 244
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 290 qeeqykvkytgintnlFVVHPITKKTIPIwISNaTH--IEYGTNAVLSIPGHNENDWNFAVKNNLKIkYVIFNPD----- 362
Cdd:PRK05729 245 ----------------TVILPLVGREIPI-IAD-EYvdPEFGTGAVKITPAHDPNDFEVGKRHNLPM-INIMDEDgtine 305
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 363 ----------------------------------HQ-----------EPKLYTS-FLDIKG-------------TLFNSQ 383
Cdd:PRK05729 306 npgeyqgldrfearkaivadleelgllvkiephtHSvghsdrsgvviEPYLSDQwFVKMKPlakpaleavengeIKFVPE 385
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 384 EFnglnlkdgtekikkilykkkilkEKINY----KLQDWCISRQRYWGTPIPMAKFKNGKMIPIPENqlpvvlPKIRKNT 459
Cdd:PRK05729 386 RW-----------------------EKTYFhwmeNIQDWCISRQLWWGHRIPAWYDEDGEVYVGREE------PEAREKA 436
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 460 NLlqqainfnskwaeifihgkhaIREIDTFDT-FmeSS---------WyyarytcPNFNTGMidsiasKYWLPVDQYIGG 529
Cdd:PRK05729 437 LL---------------------TQDEDVLDTwF--SSalwpfstlgW-------PEKTEDL------KRFYPTSVLVTG 480
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 530 ieHAIMHL----MYFRFYHkllrdfklvdF--DEPVKNLLCQGMVlseafykidsnsqrkwfnsssvlikRNTKGEiies 603
Cdd:PRK05729 481 --FDIIFFwvarMIMMGLH----------FtgQVPFKDVYIHGLV-------------------------RDEQGR---- 519
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 604 htqkgekliyagmiKMSKSKNNGIEPELIIQRYGADTIRLFIMFSAPVESDLEWKESGLKGiYR-FLKKLWMlIFNYIDI 682
Cdd:PRK05729 520 --------------KMSKSKGNVIDPLDLIDKYGADALRFTLAALASPGRDIRFDEERVEG-YRnFANKLWN-ASRFVLM 583
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 683 KNTHKKINFDFLNHQQSEL-RY---QLHKTIAKVSDDIGRRQtFNTAISEIMKLV-NQ-------LSKAPIKEEQD---K 747
Cdd:PRK05729 584 NLEGADVGELPDPEELSLAdRWilsRLNRTVAEVTEALDKYR-FDEAARALYEFIwNEfcdwyleLAKPVLQEAAKratR 662
|
890 900 910 920
....*....|....*....|....*....|....*....|....*...
gi 11134968 748 SIMRESLICIIKMLYPFTPHFCFFVWNYFNNHS---SIDNEKWPIFQK 792
Cdd:PRK05729 663 ATLAYVLEQILRLLHPFMPFITEELWQKLAPLGieeSIMLAPWPEADE 710
|
|
| ValS |
COG0525 |
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase ... |
1-172 |
2.08e-26 |
|
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440291 [Multi-domain] Cd Length: 877 Bit Score: 116.30 E-value: 2.08e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 1 MEKEYSPKKIENYVQEFWKKNKTFEVKEDPKKEKYyCLpMLPYP--SGKLHMGHVRNYTISDVISRYQRMLGKNVL-QP- 76
Cdd:COG0525 3 LPKTYDPKEVEAKWYQYWEENGYFKADPDSDKEPF-TI-VIPPPnvTGSLHMGHALNNTLQDILIRYKRMQGYNTLwQPg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 77 -------------------------MGWDAFgLpaEEAairnntdpFSWTQKNIKYMKKQLQSLGFSYDWSRE------- 124
Cdd:COG0525 81 tdhagiatqavverqlaeegksrhdLGREKF-L--ERV--------WEWKEESGGTITNQLRRLGASCDWSRErftmdeg 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 11134968 125 -----ITTchpeyyhweqwfFTKLYEKKLVYKKNSLVNWCSYDKTVLANEQVI 172
Cdd:COG0525 150 lskavREV------------FVRLYEKGLIYRGKRLVNWDPKLKTALSDLEVE 190
|
|
| PTZ00419 |
PTZ00419 |
valyl-tRNA synthetase-like protein; Provisional |
1-362 |
9.74e-26 |
|
valyl-tRNA synthetase-like protein; Provisional
Pssm-ID: 240411 [Multi-domain] Cd Length: 995 Bit Score: 114.33 E-value: 9.74e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 1 MEKEYSPKKIENYVQEFWKKNKTFEVKEDPK----KEKYYCLpmLPYP--SGKLHMGHVRNYTISDVISRYQRMLGKNVL 74
Cdd:PTZ00419 24 MAASYDPKEVESGWYEWWEKSGFFKPAEDAKslnsGKKFVIV--LPPPnvTGYLHIGHALTGAIQDSLIRYHRMKGDETL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 75 QPMGWDAFG----------LPAEEAAIRNN-------TDPFSWTQKNIKYMKKQLQSLGFSYDWSREITTCHPEYYHWEQ 137
Cdd:PTZ00419 102 WVPGTDHAGiatqvvvekkLMKEENKTRHDlgreeflKKVWEWKDKHGNNICNQLRRLGSSLDWSREVFTMDEQRSKAVK 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 138 WFFTKLYEKKLVYKKNSLVNWCSYDKTVLANEQVidgccwrcqNKIRIKQiPQwFIKIRNYAESLyqDLKKLTHWPENVK 217
Cdd:PTZ00419 182 EAFVRLYEDGLIYRDTRLVNWCCYLKTAISDIEV---------EFEEIEK-PT-KITIPGYDKKV--EVGVLWHFAYPLE 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 218 NMQRnwigrikgfeitlnvfntcQKLKVFTQRLDLLMGVTYISISSchklsinlskKNELIKKFIKKyryisqeeqykvk 297
Cdd:PTZ00419 249 DSGQ-------------------EEIVVATTRIETMLGDVAVAVHP----------KDERYKKLHGK------------- 286
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 11134968 298 ytgintnlFVVHP-ITKKTIPIwISNATHI--EYGTNAVLSIPGHNENDWNFAVKNNLKIkYVIFNPD 362
Cdd:PTZ00419 287 --------ELIHPfIPDRKIPI-IADDELVdmEFGTGAVKITPAHDPNDYEIAKRHNLPF-INIFTLD 344
|
|
| MetRS_core |
cd00814 |
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) ... |
41-224 |
6.15e-25 |
|
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) catalytic core domain. This class I enzyme aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. MetRS, which consists of the core domain and an anti-codon binding domain, functions as a monomer. However, in some species the anti-codon binding domain is followed by an EMAP domain. In this case, MetRS functions as a homodimer. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. As a result of a deletion event, MetRS has a significantly shorter core domain insertion than IleRS, ValRS, and LeuR. Consequently, the MetRS insertion lacks the editing function.
Pssm-ID: 173907 [Multi-domain] Cd Length: 319 Bit Score: 106.46 E-value: 6.15e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 41 LPYPSGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMGWDAFGLPAEEAAIRNNTDPFSWTQKNIKYMKKQLQSLGFSYD 120
Cdd:cd00814 8 LPYVNGVPHLGHLYGTVLADVFARYQRLRGYDVLFVTGTDEHGTKIEQKAEEEGVTPQELCDKYHEIFKDLFKWLNISFD 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 121 wsREITTCHPEYYHWEQWFFTKLYEKKLVYKKNSLVNWCSYDKTVLAneqvidgccwrcqnkiRIKQIPQWFIKIRNYAE 200
Cdd:cd00814 88 --YFIRTTSPRHKEIVQEFFKKLYENGYIYEGEYEGLYCVSCERFLP----------------EWREEEHYFFRLSKFQD 149
|
170 180
....*....|....*....|....*.
gi 11134968 201 SLYQDLKK--LTHWPENVKNMQRNWI 224
Cdd:cd00814 150 RLLEWLEKnpDFIWPENARNEVLSWL 175
|
|
| MetG |
COG0143 |
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA ... |
41-224 |
5.45e-24 |
|
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439913 [Multi-domain] Cd Length: 544 Bit Score: 107.12 E-value: 5.45e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 41 LPYPSGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMGWDAFGLPAEEAAIRNNTDPFSWTQKNIKYMKKQLQSLGFSYD 120
Cdd:COG0143 9 IPYANGPPHIGHLYTYIPADILARYQRLRGHDVLFVTGTDEHGTKIELAAEKEGITPQELVDRIHAEFKELFEKLGISFD 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 121 -WSReiTTChPEYYHWEQWFFTKLYEKKLVYKKN---------------SLVN----WCSYDK----------TVLANEQ 170
Cdd:COG0143 89 nFIR--TTS-PEHKELVQEIFQRLYDNGDIYKGEyegwycpecerflpdRYVEgtcpKCGAEDaygdqcencgATLEPTE 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 11134968 171 VIDGCCWRCQNKIRIKQIPQWFIKIRNYAESLYQDLKKLTHWPENVKNMQRNWI 224
Cdd:COG0143 166 LINPRSAISGAPPELREEEHYFFRLSKYQDRLLEWIEENPDIQPEVRNEVLSWL 219
|
|
| tRNA-synt_1g |
pfam09334 |
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases. |
41-224 |
3.53e-23 |
|
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases.
Pssm-ID: 401322 [Multi-domain] Cd Length: 387 Bit Score: 102.75 E-value: 3.53e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 41 LPYPSGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMGWDAFGLPAEEAAIRNNTDPFSWTQKNIKYMKKQLQSLGFSYD 120
Cdd:pfam09334 7 LPYANGPPHLGHLYSYIPADIFARYLRLRGYDVLFVCGTDEHGTPIELKAEKEGITPEELVDRYHEIHREDFKKFNISFD 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 121 WSreITTCHPEYYHWEQWFFTKLYEKKLVYKKNSLVNWCSYDKTVLANEQVIDGC------------------------- 175
Cdd:pfam09334 87 DY--GRTTSERHHELVQEFFLKLYENGYIYEKEIEQFYCPSDERFLPDRYVEGTCphcgsedargdqcencgrhleptel 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 11134968 176 ----CWRCQNKIRIKQIPQWFIKIRNYAESLYQDLKK-LTHWPENVKNMQRNWI 224
Cdd:pfam09334 165 inpkCVICGTTPEVKETEHYFFDLSKFQDKLREWIEEnNPEWPENVKNMVLEWL 218
|
|
| IleRS_core |
cd00818 |
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases ... |
42-224 |
6.37e-22 |
|
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases (IleRS) catalytic core domain . This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. IleRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173909 [Multi-domain] Cd Length: 338 Bit Score: 98.07 E-value: 6.37e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 42 PYPSGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMGWDAFGLPAE-----EAAIRNNTDPFSWT------------QKN 104
Cdd:cd00818 10 PYANGLPHYGHALNKILKDIINRYKTMQGYYVPRRPGWDCHGLPIElkvekELGISGKKDIEKMGiaefnakcrefaLRY 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 105 IKYMKKQLQSLGFSYDWSREITTCHPEYYHWEQWFFTKLYEKKLVYKKNSLVNWcsydktvlaneQVIdgccwrcqnkir 184
Cdd:cd00818 90 VDEQEEQFQRLGVWVDWENPYKTMDPEYMESVWWVFKQLHEKGLLYRGYKVVPW-----------PLI------------ 146
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 11134968 185 IKQIPQWFIKIRNYAESLYQDLKKlTHW-PENVKNMQRNWI 224
Cdd:cd00818 147 YRATPQWFIRVTKIKDRLLEANDK-VNWiPEWVKNRFGNWL 186
|
|
| PRK11893 |
PRK11893 |
methionyl-tRNA synthetase; Reviewed |
33-218 |
1.29e-21 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237012 [Multi-domain] Cd Length: 511 Bit Score: 99.57 E-value: 1.29e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 33 EKYYCLPMLPYPSGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMGWDAFGLPAEEAAIRNNTDPFSWTQKNIKYMKKQL 112
Cdd:PRK11893 1 KKFYITTPIYYPNGKPHIGHAYTTLAADVLARFKRLRGYDVFFLTGTDEHGQKIQRKAEEAGISPQELADRNSAAFKRLW 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 113 QSLGFSYD-WSReiTTcHPEYYHWEQWFFTKLYEKKLVYKKNSLVNWCSYDKTVLANEQVIDG--CCWRCQNKIRIKQIP 189
Cdd:PRK11893 81 EALNISYDdFIR--TT-DPRHKEAVQEIFQRLLANGDIYLGKYEGWYCVRCEEFYTESELIEDgyRCPPTGAPVEWVEEE 157
|
170 180 190
....*....|....*....|....*....|.
gi 11134968 190 QWFIKIRNYAESLYQDLKKLTHW--PENVKN 218
Cdd:PRK11893 158 SYFFRLSKYQDKLLELYEANPDFiqPASRRN 188
|
|
| valS |
PRK14900 |
valyl-tRNA synthetase; Provisional |
1-799 |
4.25e-20 |
|
valyl-tRNA synthetase; Provisional
Pssm-ID: 237855 [Multi-domain] Cd Length: 1052 Bit Score: 96.21 E-value: 4.25e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 1 MEKEYSPKKIENYVQEFWKKNKTFEVKEDPKKEKYYCLpMLPYP--SGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMG 78
Cdd:PRK14900 15 LAKGYEHREVEARWYPFWQERGYFHGDEHDRTRPPFSI-VLPPPnvTGSLHLGHALTATLQDVLIRWKRMSGFNTLWLPG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 79 WDAFGLPAE----------EAAIRNN--TDPF-----SWTQKNIKYMKKQLQSLGFSYDWSREITTCHPEYYHWEQWFFT 141
Cdd:PRK14900 94 TDHAGIATQmivekelkktEKKSRHDlgREAFlervwAWKEQYGSRIGEQHKALGASLDWQRERFTMDEGLSRAVREVFV 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 142 KLYEKKLVYKKNSLVNWCSYDKTVLANEQVidgccwrcqnkirikqipqwfikirnyaesLYQDLKKLTHWpenvknmqr 221
Cdd:PRK14900 174 RLHEEGLIYREKKLINWCPDCRTALSDLEV------------------------------EHEEAHQGELW--------- 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 222 nwigrikgfEITLNVFNTCQKLKVFTQRLDLLMGVTYISIsscHKLSinlskknelikkfiKKYRYISQEEqykvkytgi 301
Cdd:PRK14900 215 ---------SFAYPLADGSGEIVVATTRPETMLGDTAVAV---HPLD--------------PRYMALHGKK--------- 259
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 302 ntnlfVVHPITKKTIPIwISNATHIE--YGTNAVLSIPGHNENDWNFAVKNNLKIKYVIfNPDHQEPK------------ 367
Cdd:PRK14900 260 -----VRHPITGRTFPI-VADAILVDpkFGTGAVKVTPAHDFNDFEVGKRHGLEMITVI-GPDGRMTAeagplagldrfe 332
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 368 --------LYTSFLDIK--------GTLFNSQEFNGLNLKD------------GTEKIKKILYKKKILKEKINY-----K 414
Cdd:PRK14900 333 arkevkrlLAEQGLDRGakphvlplGRCQRSATILEPLLSDqwyvrieplarpAIEAVEQGRTRFIPEQWTNTYmawmrN 412
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 415 LQDWCISRQRYWGTPIPMAKFKNGKmiPIPENQLPVVLPKIRKNTnllqqainfnskwaeifihgkhAIREIDTFDTFME 494
Cdd:PRK14900 413 IHDWCISRQLWWGHQIPAWYCPDGH--VTVARETPEACSTCGKAE----------------------LRQDEDVLDTWFS 468
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 495 SS-WYYARYTCPNfNTGMIDSIASKYWLPVDQYIGGIEHAIMHLMYFRFYHkllrdfklvdfDEPVKNLLCQGMVlseaf 573
Cdd:PRK14900 469 SGlWPFSTMGWPE-QTDTLRTFYPTSVMETGHDIIFFWVARMMMMGLHFMG-----------EVPFRTVYLHPMV----- 531
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 574 ykidsnsqrkwfnsssvlikRNTKGEiieshtqkgekliyagmiKMSKSKNNGIEPELIIQRYGADTIRLFIMFSAPVES 653
Cdd:PRK14900 532 --------------------RDEKGQ------------------KMSKTKGNVIDPLVITEQYGADALRFTLAALTAQGR 573
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 654 DLEWKESGLKGIYRFLKKLWmlifnyidikNTHK--KINFDFLNHQQSEL---------RYQLHKTIAKVSDDIGRRQT- 721
Cdd:PRK14900 574 DIKLAKERIEGYRAFANKLW----------NASRfaLMNLSGYQERGEDParlartpadRWILARLQRAVNETVEALEAf 643
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 722 -FNTAISEIMKLV--------NQLSKA------PIKEEQDKSIMRESLICIIKMLYPFTPHFCFFVWNYFnnHSSIDNEK 786
Cdd:PRK14900 644 rFNDAANAVYAFVwhelcdwyIELAKEalasedPEARRSVQAVLVHCLQTSYRLLHPFMPFITEELWHVL--RAQVGASA 721
|
890
....*....|...
gi 11134968 787 WPifqKDILSKKY 799
Cdd:PRK14900 722 WA---DSVLAAEY 731
|
|
| PLN02381 |
PLN02381 |
valyl-tRNA synthetase |
1-362 |
4.26e-16 |
|
valyl-tRNA synthetase
Pssm-ID: 215214 [Multi-domain] Cd Length: 1066 Bit Score: 83.02 E-value: 4.26e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 1 MEKEYSPKKIENYVQEFWKKNKTFevKEDPKKEKYYCLPMLPYP--SGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMG 78
Cdd:PLN02381 96 MAKQYSPSAVEKSWYAWWEKSGYF--GADAKSSKPPFVIVLPPPnvTGALHIGHALTAAIEDTIIRWKRMSGYNALWVPG 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 79 WDAFGLPA----EEAAIRNN-------------TDPFSWTQKNIKYMKKQLQSLGFSYDWSREITTCHPEYYHWEQWFFT 141
Cdd:PLN02381 174 VDHAGIATqvvvEKKLMRERhltrhdigreefvSEVWKWKDEYGGTILNQLRRLGASLDWSRECFTMDEQRSKAVTEAFV 253
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 142 KLYEKKLVYKKNSLVNWCSYDKTVLANEQVidgccwrcqNKIRIKQipqwfikirnyaeslyqdlKKLTHWPENVKNMQr 221
Cdd:PLN02381 254 RLYKEGLIYRDIRLVNWDCTLRTAISDVEV---------DYIDIKE-------------------RTLLKVPGYDKPVE- 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 222 nwIGRIKGFEITLNvfNTCQKLKVFTQRLDLLMGVTYISISschklsinlskknelikkfikkyryiSQEEQYKVKYtgi 301
Cdd:PLN02381 305 --FGVLTSFAYPLE--GGLGEIVVATTRIETMLGDTAIAIH--------------------------PDDERYKHLH--- 351
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 11134968 302 ntNLFVVHPITKKTIPIwISNATHIE--YGTNAVLSIPGHNENDWNFAVKNNLKIkYVIFNPD 362
Cdd:PLN02381 352 --GKFAVHPFNGRKLPI-ICDAILVDpnFGTGAVKITPAHDPNDFEVGKRHNLEF-INIFTDD 410
|
|
| PLN02882 |
PLN02882 |
aminoacyl-tRNA ligase |
3-168 |
3.43e-15 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215477 [Multi-domain] Cd Length: 1159 Bit Score: 80.15 E-value: 3.43e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 3 KEYSPKKIENYVQEFWKKNKTFE--VKEDPKKEKY--YCLPmlPYPSGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMG 78
Cdd:PLN02882 6 KDFSFPKQEEKILSLWSEIDAFKtqLKRTEGLPEYifYDGP--PFATGLPHYGHILAGTIKDIVTRYQSMTGHHVTRRFG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 79 WDAFGLPAE------------EAAIRNNTDPFSWTQKNI--KYMK---KQLQSLGFSYDWSREITTCHPEYYHWEQWFFT 141
Cdd:PLN02882 84 WDCHGLPVEyeidkklgikrrDDVLKMGIDKYNEECRSIvtRYSKeweKTVTRTGRWIDFENDYKTMDPKFMESVWWVFK 163
|
170 180
....*....|....*....|....*..
gi 11134968 142 KLYEKKLVYKKNSLVNWCSYDKTVLAN 168
Cdd:PLN02882 164 QLFEKGLVYKGFKVMPYSTACKTPLSN 190
|
|
| PLN02843 |
PLN02843 |
isoleucyl-tRNA synthetase |
11-167 |
1.33e-14 |
|
isoleucyl-tRNA synthetase
Pssm-ID: 215452 [Multi-domain] Cd Length: 974 Bit Score: 78.27 E-value: 1.33e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 11 ENYVQEFWKKNKTFE-VKEDPKKEKYYCLPMLPYPSGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMGWDAFGLPAE-- 87
Cdd:PLN02843 9 EPEIQKLWEENQVYKrVSDRNNGESFTLHDGPPYANGDLHIGHALNKILKDFINRYQLLQGKKVHYVPGWDCHGLPIElk 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 88 -----EAAIRNNTDPFSWTQKNIKYMKK-------QLQSLGFSYDWSREITTCHPEYYHWEQWFFTKLYEKKLVYKKNSL 155
Cdd:PLN02843 89 vlqslDQEARKELTPIKLRAKAAKFAKKtvdtqreSFKRYGVWGDWENPYLTLDPEYEAAQIEVFGQMFLNGYIYRGRKP 168
|
170
....*....|..
gi 11134968 156 VNWCSYDKTVLA 167
Cdd:PLN02843 169 VHWSPSSRTALA 180
|
|
| metG |
PRK00133 |
methionyl-tRNA synthetase; Reviewed |
41-224 |
1.06e-13 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 234655 [Multi-domain] Cd Length: 673 Bit Score: 75.19 E-value: 1.06e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 41 LPYPSGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMGWDAFGLPAEEAAIRNNTDPfswtQKNIKYMKKQ----LQSLG 116
Cdd:PRK00133 10 LPYANGPIHLGHLVEYIQADIWVRYQRMRGHEVLFVCADDAHGTPIMLKAEKEGITP----EELIARYHAEhkrdFAGFG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 117 FSYD-WSReitTCHPEYYHWEQWFFTKLYEKKLVYKKNSLVNWCSYDKTVLANEQVIDGC------------CWRCQ--- 180
Cdd:PRK00133 86 ISFDnYGS---THSEENRELAQEIYLKLKENGYIYEKTIEQLYDPEKGMFLPDRFVKGTCpkcgaedqygdnCEVCGaty 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 11134968 181 --------------NKIRIKQIPQWFIKIRNYAESLYQDLKKLTHWPENVKNMQRNWI 224
Cdd:PRK00133 163 sptelinpksaisgATPVLKESEHFFFKLPRFEEFLKEWITRSGELQPNVANKMKEWL 220
|
|
| PLN02943 |
PLN02943 |
aminoacyl-tRNA ligase |
6-788 |
5.63e-13 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215509 [Multi-domain] Cd Length: 958 Bit Score: 73.05 E-value: 5.63e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 6 SPKKIENY--VQEFWKKNktFEVKEDPkkekyYCLPMLPyP--SGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMGWDA 81
Cdd:PLN02943 65 SEERIYNWweSQGYFKPN--FDRGGDP-----FVIPMPP-PnvTGSLHMGHAMFVTLEDIMVRYNRMKGRPTLWIPGTDH 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 82 FGLP---------AEEAAIRNNT--DPFS-----WTQKNIKYMKKQLQSLGFSYDWSREITTCHPEYYHWEQWFFTKLYE 145
Cdd:PLN02943 137 AGIAtqlvvekmlASEGIKRTDLgrDEFTkrvweWKEKYGGTITNQIKRLGASCDWSRERFTLDEQLSRAVVEAFVRLHE 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 146 KKLVYKKNSLVNWCSYDKTVLANEQVidgccwrcqnkirikqipqwfikirNYAESlyqdlkklthwPENVKNMQRNWIG 225
Cdd:PLN02943 217 KGLIYQGSYMVNWSPNLQTAVSDLEV-------------------------EYSEE-----------PGTLYYIKYRVAG 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 226 RIKGFeitlnvfntcqkLKVFTQRLDLLMGVTYISIsschklsinlskknelikkfikkyryISQEEQYKvKYTGintNL 305
Cdd:PLN02943 261 GSEDF------------LTIATTRPETLFGDVAIAV--------------------------NPEDDRYS-KYIG---KM 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 306 FVVHPITKKTIPIWISNATHIEYGTNAVLSIPGHNENDWNFAVKNNLKIKYViFNPD---HQEPKLYtsFLDIKGTLFNS 382
Cdd:PLN02943 299 AIVPMTYGRHVPIIADRYVDKDFGTGVLKISPGHDHNDYLLARKLGLPILNV-MNKDgtlNEVAGLY--WFEAREKLWSD 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 383 QEFNGLNLKD------------GTE------------------------KIKKILYKKKILKEKI-NYKL---QDWCISR 422
Cdd:PLN02943 376 LEETGLAVKKephtlrvprsqrGGEvieplvskqwfvtmeplaekalkaVENGELTIIPERFEKIyNHWLsniKDWCISR 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 423 QRYWGTPIPMAkFKNGKMIpipENQLPVVlpkiRKNTNLLQQAINFNSKWAEIFihgkhaiREIDTFDTFMESS-WYYAR 501
Cdd:PLN02943 456 QLWWGHRIPVW-YIVGKDC---EEDYIVA----RSAEEALEKAREKYGKDVEIY-------QDPDVLDTWFSSAlWPFST 520
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 502 YTCPNFNTGMIDSIASKYWLPVDQYIGGIEHAIMHLMYFRFYHKLlrdfklvdfdePVKNLLCQGMVlseafykidsnsq 581
Cdd:PLN02943 521 LGWPDVSAEDFKKFYPTTVLETGHDILFFWVARMVMMGIEFTGTV-----------PFSYVYLHGLI------------- 576
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 582 rkwfnsssvlikRNTKGEiieshtqkgekliyagmiKMSKSKNNGIEPELIIQRYGADTIRlFIMFSAPVESDLEWKESG 661
Cdd:PLN02943 577 ------------RDSQGR------------------KMSKTLGNVIDPLDTIKEFGTDALR-FTLALGTAGQDLNLSTER 625
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 662 LKGIYRFLKKLW----MLIFNYIDIKNTH--KKINFDFLNHQQSELRY---------QLHKTIAKVS--------DDIGr 718
Cdd:PLN02943 626 LTSNKAFTNKLWnagkFVLQNLPSQSDTSawEHILACKFDKEESLLSLplpecwvvsKLHELIDSVTtsydkyffGDVG- 704
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 11134968 719 RQTFNTAISEIMKLVNQLSKAPIKEEQDKSIMRESLIC-------IIKMLYPFTPHFCFFVWNYF-NNHSSIDNEKWP 788
Cdd:PLN02943 705 REIYDFFWSDFADWYIEASKTRLYHSGDNSALSRAQAVllyvfenILKLLHPFMPFVTEELWQALpYRKEALIVSPWP 782
|
|
| PRK12267 |
PRK12267 |
methionyl-tRNA synthetase; Reviewed |
43-202 |
2.39e-11 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237028 [Multi-domain] Cd Length: 648 Bit Score: 67.52 E-value: 2.39e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 43 YPSGKLHMGHVrnYT--ISDVISRYQRMLGKNVLQPMGWDAFGLPAEEAAIRNNTDPFSWTQKNIKYMKKQLQSLGFSYD 120
Cdd:PRK12267 14 YPNGKPHIGHA--YTtiAADALARYKRLQGYDVFFLTGTDEHGQKIQQAAEKAGKTPQEYVDEISAGFKELWKKLDISYD 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 121 wsREI-TTchpEYYHWE--QWFFTKLYEKKLVYKKNSLVNWCSYDKTVLANEQVIDGC-CWRCQNKIRIKQIPQWFIKIR 196
Cdd:PRK12267 92 --KFIrTT---DERHKKvvQKIFEKLYEQGDIYKGEYEGWYCVSCETFFTESQLVDGGkCPDCGREVELVKEESYFFRMS 166
|
....*.
gi 11134968 197 NYAESL 202
Cdd:PRK12267 167 KYQDRL 172
|
|
| Anticodon_1 |
pfam08264 |
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA ... |
700-825 |
3.59e-11 |
|
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA synthetases. The domain binds to the anticodon of the tRNA ligase.
Pssm-ID: 400523 [Multi-domain] Cd Length: 141 Bit Score: 61.65 E-value: 3.59e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 700 ELRYQLHKTIAKVSDDIGRRQtFNTAISEIMKLVN--------QLSKAPIKEEQDKS----IMRESLICIIKMLYPFTPH 767
Cdd:pfam08264 3 WILSRLNKLIKEVTEAYENYR-FNTAAQALYEFFWndlsdwylELIKDRLYGEEPDSraqtTLYEVLETLLRLLAPFMPF 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 11134968 768 FCFFVWnyfnNHSSIDNEKWPIFQKDILSKKYSTI-----VAQINGKKRCATKISDSLTKEEI 825
Cdd:pfam08264 82 ITEELW----QKESIHLAPWPEDAELEEAELEEAFelrqeIVQAIRKLRSELKIKKSLPLEVV 140
|
|
| MetG |
COG0143 |
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA ... |
618-789 |
9.96e-11 |
|
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439913 [Multi-domain] Cd Length: 544 Bit Score: 65.13 E-value: 9.96e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 618 KMSKSKNNGIEPELIIQRYGADTIRLFIMFSAPVESDLE--WKE------SGLKGIY-----RFLKklwmLIFNYID--I 682
Cdd:COG0143 327 KMSKSRGNVIDPDDLLDRYGPDALRYYLLREVPFGQDGDfsWEDfvarvnSDLANDLgnlasRTLS----MIHKYFDgkV 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 683 KNTHKKINFDflnhqqSELRYQLHKTIAKVSDDIGRRQtFNTAISEIMKLV---NQL--SKAP---IKEEQD---KSIMR 751
Cdd:COG0143 403 PEPGELTEAD------EELLAEAEAALEEVAEAMEAFE-FRKALEEIMALAraaNKYidETAPwklAKDEDPerlATVLY 475
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 11134968 752 ---ESLICIIKMLYPFTPHFCFFVWNYFN---NHSSIDNEKWPI 789
Cdd:COG0143 476 tllEALRILAILLKPFLPETAEKILEQLGlegDELTWEDAGWPL 519
|
|
| PRK11893 |
PRK11893 |
methionyl-tRNA synthetase; Reviewed |
618-766 |
2.00e-09 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237012 [Multi-domain] Cd Length: 511 Bit Score: 61.05 E-value: 2.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 618 KMSKSKNNGIEPELIIQRYGADTIRLFIMFSAPVESDLEWKESGLKGIYR-----FLKKL----WMLIFNYIDIKNTHKK 688
Cdd:PRK11893 299 KMSKSLGNVIDPFDLVDEYGVDAVRYFLLREIPFGQDGDFSREAFINRINadlanDLGNLaqrtLSMIAKNFDGKVPEPG 378
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 689 InfdfLNHQQSELRYQLHKTIAKVSDDIGRRQtFNTAISEIMKLVNQLSK--------APIKEEQDK-----SIMRESLI 755
Cdd:PRK11893 379 A----LTEADEALLEAAAALLERVRAAMDNLA-FDKALEAILALVRAANKyideqapwSLAKTDPERlatvlYTLLEVLR 453
|
170
....*....|.
gi 11134968 756 CIIKMLYPFTP 766
Cdd:PRK11893 454 GIAVLLQPVMP 464
|
|
| PLN02959 |
PLN02959 |
aminoacyl-tRNA ligase |
9-90 |
1.15e-08 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215518 [Multi-domain] Cd Length: 1084 Bit Score: 58.93 E-value: 1.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 9 KIENYVQEFWKKNKTFEV---KEDPKK-EKYYCLPMLPYPSGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMGWDAFGL 84
Cdd:PLN02959 17 EIEVAVQKWWEEEKVFEAeagDEPPKPgEKFFGNFPYPYMNGLLHLGHAFSLSKLEFAAAYHRLRGANVLLPFAFHCTGM 96
|
....*.
gi 11134968 85 PAEEAA 90
Cdd:PLN02959 97 PIKASA 102
|
|
| PRK12267 |
PRK12267 |
methionyl-tRNA synthetase; Reviewed |
618-767 |
6.06e-08 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237028 [Multi-domain] Cd Length: 648 Bit Score: 56.35 E-value: 6.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 618 KMSKSKNNGIEPELIIQRYGADTIRLFIMFSAPVESDLEWKESGLkgIYRF-----------LKKLWMLIFNYID--IKN 684
Cdd:PRK12267 299 KMSKSKGNVVDPEELVDRYGLDALRYYLLREVPFGSDGDFSPEAL--VERInsdlandlgnlLNRTVAMINKYFDgeIPA 376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 685 THKKINFDflnhqqSELRYQLHKTIAKVSDDIGRRQtFNTAISEIMKLVNQLSK-----AP---IKEEQDK----SIMR- 751
Cdd:PRK12267 377 PGNVTEFD------EELIALAEETLKNYEELMEELQ-FSRALEEVWKLISRANKyidetAPwvlAKDEGKKerlaTVMYh 449
|
170
....*....|....*...
gi 11134968 752 --ESLICIIKMLYPFTPH 767
Cdd:PRK12267 450 laESLRKVAVLLSPFMPE 467
|
|
| PTZ00427 |
PTZ00427 |
isoleucine-tRNA ligase, putative; Provisional |
11-151 |
1.47e-07 |
|
isoleucine-tRNA ligase, putative; Provisional
Pssm-ID: 173617 [Multi-domain] Cd Length: 1205 Bit Score: 55.36 E-value: 1.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 11 ENYVQEFWKK----NKTFEVKEDPKKEKYYCLPmlPYPSGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMGWDAFGLPA 86
Cdd:PTZ00427 78 EEKVLKYWKSidafNTSNKLAKNKKAYIFYDGP--PFATGLPHYGHLLAGIIKDCVTRYFYQCGFSVERKFGWDCHGLPI 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 87 E------------EAAIRNNTDPFSWTQKNI--KYMK---KQLQSLGFSYDWSREITTCHPEYYHWEQWFFTKLYEKKLV 149
Cdd:PTZ00427 156 EyeiekenninkkEDILKMGIDVYNEKCRGIvlKYSNewvKTVERIGRWIDFKNDYKTMDKTFMESVWWVFSELYKNNYV 235
|
..
gi 11134968 150 YK 151
Cdd:PTZ00427 236 YK 237
|
|
| CysS |
COG0215 |
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA ... |
615-761 |
2.31e-07 |
|
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439985 [Multi-domain] Cd Length: 465 Bit Score: 54.34 E-value: 2.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 615 GMI-----KMSKSKNNGIEPELIIQRYGADTIRLFIM---------FSapvESDLEWKESGLKGIYRFLKKLWMLIFNYI 680
Cdd:COG0215 257 GFLtvngeKMSKSLGNFFTVRDLLKKYDPEVLRFFLLsahyrspldFS---EEALEEAEKALERLYNALRRLEEALGAAD 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 681 DIKNTHKKINFDFlnhqqselryqlhktIAKVSDDigrrqtFNT--AISEIMKLVNQLSKApIKEEQDKSIMRESLICII 758
Cdd:COG0215 334 SSAEEIEELREEF---------------IAAMDDD------FNTpeALAVLFELVREINKA-LDEGEDKAALAALAALLR 391
|
...
gi 11134968 759 KML 761
Cdd:COG0215 392 ALG 394
|
|
| PTZ00427 |
PTZ00427 |
isoleucine-tRNA ligase, putative; Provisional |
416-667 |
1.04e-06 |
|
isoleucine-tRNA ligase, putative; Provisional
Pssm-ID: 173617 [Multi-domain] Cd Length: 1205 Bit Score: 52.66 E-value: 1.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 416 QDWCISRQRYWGTPIPM-AKFKNGKMIPIPENQLPVVLPKIRKNTNLLQQAINF----NSKWAEifiHGKHAiREIDTFD 490
Cdd:PTZ00427 569 KDWCISRNRYWGTPIPIwADEKMETVICVESIKHLEELSGVKNINDLHRHFIDHieikNPKGKT---YPKLK-RIPEVFD 644
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 491 TFMES-SWYYARYTCPnFNTGMIDsiaSKYWLPVDQYIGGIEHAimhlmyFRFYHKLLRDFKLVDFDEPVKNLLCQGMVL 569
Cdd:PTZ00427 645 CWFESgSMPYAKVHYP-FSTEKED---FHKIFPADFIAEGLDQT------RGWFYTLLVISTLLFDKAPFKNLICNGLVL 714
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 570 SeafykidsnSQRKwfnsssvlikrntkgeiieshtqkgekliyagmiKMSKSKNNGIEPELIIQRYGADTIRLFIMFSA 649
Cdd:PTZ00427 715 A---------SDGK----------------------------------KMSKRLKNYPDPLYILDKYGADSLRLYLINSV 751
|
250
....*....|....*....
gi 11134968 650 PVESD-LEWKESGLKGIYR 667
Cdd:PTZ00427 752 AVRAEnLKFQEKGVNEVVK 770
|
|
| PLN02224 |
PLN02224 |
methionine-tRNA ligase |
41-233 |
5.88e-04 |
|
methionine-tRNA ligase
Pssm-ID: 177869 [Multi-domain] Cd Length: 616 Bit Score: 43.55 E-value: 5.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 41 LPYPSGKLHMGHVRNYTISDVISRYQRMLGKNVLQPMGWDAFGLPAEEAAIRNNTDPFSWTQKNIKYMKKQLQSLGFSYD 120
Cdd:PLN02224 77 LYYVNAPPHMGSAYTTIAADSIARFQRLLGKKVIFITGTDEHGEKIATSAAANGRNPPEHCDIISQSYRTLWKDLDIAYD 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11134968 121 wsREITTCHPEYYHWEQWFFTKLYEKKLVYKKNSLVNWC-SYDKTVLANEQVIDGCCWRCQNKIRIKQIPQWFIKIRNYA 199
Cdd:PLN02224 157 --KFIRTTDPKHEAIVKEFYARVFANGDIYRADYEGLYCvNCEEYKDEKELLENNCCPVHQMPCVARKEDNYFFALSKYQ 234
|
170 180 190
....*....|....*....|....*....|....*..
gi 11134968 200 ESLYQDLKKLTHW--PENVKNMQRNWIGR-IKGFEIT 233
Cdd:PLN02224 235 KPLEDILAQNPRFvqPSYRLNEVQSWIKSgLRDFSIS 271
|
|
| |
