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Conserved domains on  [gi|2828196|sp|P30990|]
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RecName: Full=Neurotensin/neuromedin N; Contains: RecName: Full=Large neuromedin N; AltName: Full=NmN-125; Contains: RecName: Full=Neuromedin N; Short=NN; Short=NmN; Contains: RecName: Full=Neurotensin; Short=NT; Contains: RecName: Full=Tail peptide; Flags: Precursor

Protein Classification

Pro-NT_NN domain-containing protein( domain architecture ID 10538427)

Pro-NT_NN domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Pro-NT_NN pfam07421
Neurotensin/neuromedin N precursor; This family contains the precursor of bacterial ...
 7-169 1.34e-89

Neurotensin/neuromedin N precursor; This family contains the precursor of bacterial neurotensin/neuromedin N (approximately 170 residues long). This the common precursor of two biologically active related peptides, neurotensin and neuromedin N. It undergoes tissue-specific processing leading to the formation in some tissues and cancer cell lines of large peptides ending with the neurotensin or neuromedin N sequence.


:

Pssm-ID: 462161  Cd Length: 161  Bit Score: 258.59  E-value: 1.34e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2828196      7 IQLVCMLLLAFSSWSLCSDSEEEMKALEADFLTNMHTSKISKAHVPSWKMTLLNVCSLVNNLNSPAEETGEVHEEELVAR 86
Cdd:pfam07421   1 IQLVCMLLLAFTSWSLCSDSDEEMKALEAELLTSLYTSKVNKASAPSWKMTLLNVCRLINNLNSQAEETGGNEEEDLITR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2828196     87 RKLPTALDGFSLEAMLTIYQLHKIChsRAFQHWELIQEDILDTGNDKNGKEEVIKRKIPYILKRQLYENKPRRPYILKRD 166
Cdd:pfam07421  81 RQLPTFLDGFSLEALLTIYQLQKLC--RAFQQWELIQQDVQDYLNLKQNKDEPLKRKSPYILKRQLHTNKPRRPYILKRS 158


                  ...
gi 2828196    167 SYY 169
Cdd:pfam07421 159 SYY 161
 
Name Accession Description Interval E-value
Pro-NT_NN pfam07421
Neurotensin/neuromedin N precursor; This family contains the precursor of bacterial ...
 7-169 1.34e-89

Neurotensin/neuromedin N precursor; This family contains the precursor of bacterial neurotensin/neuromedin N (approximately 170 residues long). This the common precursor of two biologically active related peptides, neurotensin and neuromedin N. It undergoes tissue-specific processing leading to the formation in some tissues and cancer cell lines of large peptides ending with the neurotensin or neuromedin N sequence.


Pssm-ID: 462161  Cd Length: 161  Bit Score: 258.59  E-value: 1.34e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2828196      7 IQLVCMLLLAFSSWSLCSDSEEEMKALEADFLTNMHTSKISKAHVPSWKMTLLNVCSLVNNLNSPAEETGEVHEEELVAR 86
Cdd:pfam07421   1 IQLVCMLLLAFTSWSLCSDSDEEMKALEAELLTSLYTSKVNKASAPSWKMTLLNVCRLINNLNSQAEETGGNEEEDLITR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2828196     87 RKLPTALDGFSLEAMLTIYQLHKIChsRAFQHWELIQEDILDTGNDKNGKEEVIKRKIPYILKRQLYENKPRRPYILKRD 166
Cdd:pfam07421  81 RQLPTFLDGFSLEALLTIYQLQKLC--RAFQQWELIQQDVQDYLNLKQNKDEPLKRKSPYILKRQLHTNKPRRPYILKRS 158


                  ...
gi 2828196    167 SYY 169
Cdd:pfam07421 159 SYY 161
 
Name Accession Description Interval E-value
Pro-NT_NN pfam07421
Neurotensin/neuromedin N precursor; This family contains the precursor of bacterial ...
 7-169 1.34e-89

Neurotensin/neuromedin N precursor; This family contains the precursor of bacterial neurotensin/neuromedin N (approximately 170 residues long). This the common precursor of two biologically active related peptides, neurotensin and neuromedin N. It undergoes tissue-specific processing leading to the formation in some tissues and cancer cell lines of large peptides ending with the neurotensin or neuromedin N sequence.


Pssm-ID: 462161  Cd Length: 161  Bit Score: 258.59  E-value: 1.34e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2828196      7 IQLVCMLLLAFSSWSLCSDSEEEMKALEADFLTNMHTSKISKAHVPSWKMTLLNVCSLVNNLNSPAEETGEVHEEELVAR 86
Cdd:pfam07421   1 IQLVCMLLLAFTSWSLCSDSDEEMKALEAELLTSLYTSKVNKASAPSWKMTLLNVCRLINNLNSQAEETGGNEEEDLITR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2828196     87 RKLPTALDGFSLEAMLTIYQLHKIChsRAFQHWELIQEDILDTGNDKNGKEEVIKRKIPYILKRQLYENKPRRPYILKRD 166
Cdd:pfam07421  81 RQLPTFLDGFSLEALLTIYQLQKLC--RAFQQWELIQQDVQDYLNLKQNKDEPLKRKSPYILKRQLHTNKPRRPYILKRS 158


                  ...
gi 2828196    167 SYY 169
Cdd:pfam07421 159 SYY 161
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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