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Conserved domains on  [gi|55584090|sp|P27398|]
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RecName: Full=Calpain-D; AltName: Full=Calcium-activated neutral proteinase D; Short=CANP D; AltName: Full=Small optic lobes protein

Protein Classification

zinc finger Ran-binding domain-containing protein( domain architecture ID 11101795)

zinc finger Ran-binding domain-containing protein similar to Arabidopsis thaliana chloroplastic zinc finger protein VAR3, which is involved in C-to-U editing of chloroplastic RNA

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CysPc smart00230
Calpain-like thiol protease family; Calpain-like thiol protease family (peptidase family C2). ...
1001-1328 1.08e-140

Calpain-like thiol protease family; Calpain-like thiol protease family (peptidase family C2). Calcium activated neutral protease (large subunit).


:

Pssm-ID: 128526  Cd Length: 318  Bit Score: 435.60  E-value: 1.08e-140
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090    1001 WQNIIQYCRDNSELFVDDSFPPAPKSLYYNPASGagegnPVVQWRRPHEINCDggayPPWAVFRTPlPSDICQGVLGNCW 1080
Cdd:smart00230    1 YEALRQYCKESGTLFEDPLFPANNGSLFFSQRQR-----KFVVWKRPHEIFEN----PPFIVGGAS-RTDICQGVLGDCW 70
                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090    1081 LLSALAVLAEREDLVKEVLV-TKEIC--GQGAYQVRLCKDGKWTTVLVDDLLPCDKRGHLVYSQAKRKQLWVPLIEKAVA 1157
Cdd:smart00230   71 LLAALASLTLREKLLDRVIPhDQEFSenYAGIFHFRFWRFGKWVDVVIDDRLPTYNGELVFMHSNSRNEFWSALLEKAYA 150
                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090    1158 KIHGCYEALVSGRAIEGLATLTGAPCESIPLQAsslPMPSEDELDKDLIWAQLLSsrcvrFLMGASCGGGNmKVDEEEYQ 1237
Cdd:smart00230  151 KLNGCYEALKGGSTTEALEDLTGGVAESIDLKE---ASKDPDNLFEDLFKAFERG-----SLMGCSIGAGT-AVEEEEQK 221
                           250       260       270       280       290       300       310       320
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090    1238 QKGLRPRHAYSVLDVKDIQGHR--LLKLRNPWGHYSWRGDWSDDSSLWT---DDLRDALMPHGASEGVFWISFEDVLNYF 1312
Cdd:smart00230  222 DCGLVKGHAYSVTDVREVQGRRqeLLRLRNPWGQVEWNGPWSDDSPEWRsvsASEKKNLGLTFDDDGEFWMSFEDFLRHF 301
                           330
                    ....*....|....*.
gi 55584090    1313 DCIDICKVRSGWNEVR 1328
Cdd:smart00230  302 DKVEICNLNPDSLEER 317
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
927-954 3.11e-06

Zn-finger in Ran binding protein and others;


:

Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 45.04  E-value: 3.11e-06
                           10        20
                   ....*....|....*....|....*...
gi 55584090    927 STKKWQCPACTYDNCAASVVCDICSSPR 954
Cdd:pfam00641    1 REGDWDCSKCLVQNFATSTKCVACQAPK 28
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
6-34 5.45e-06

Zn-finger in Ran binding protein and others;


:

Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 44.27  E-value: 5.45e-06
                           10        20
                   ....*....|....*....|....*....
gi 55584090      6 SVLQWSCTKCNTINPTESLKCFNCGTVRK 34
Cdd:pfam00641    1 REGDWDCSKCLVQNFATSTKCVACQAPKP 29
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
704-731 1.49e-05

Zn-finger in Ran binding protein and others;


:

Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 43.11  E-value: 1.49e-05
                           10        20
                   ....*....|....*....|....*...
gi 55584090    704 RDEPWTCKKCTLVNYSTAMACVVCGGSK 731
Cdd:pfam00641    1 REGDWDCSKCLVQNFATSTKCVACQAPK 28
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
747-774 1.73e-05

Zn-finger in Ran binding protein and others;


:

Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 43.11  E-value: 1.73e-05
                           10        20
                   ....*....|....*....|....*...
gi 55584090    747 EFWTCSHCTLKNSLHSPVCSACKSHRQP 774
Cdd:pfam00641    3 GDWDCSKCLVQNFATSTKCVACQAPKPD 30
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
135-164 3.91e-05

Zn-finger in Ran binding protein and others;


:

Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 41.95  E-value: 3.91e-05
                           10        20        30
                   ....*....|....*....|....*....|
gi 55584090    135 LNRRWVCHACGTDNSSVTWHCLICDTVSYL 164
Cdd:pfam00641    1 REGDWDCSKCLVQNFATSTKCVACQAPKPD 30
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
643-672 4.97e-04

Zn-finger in Ran binding protein and others;


:

Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 38.87  E-value: 4.97e-04
                           10        20        30
                   ....*....|....*....|....*....|
gi 55584090    643 RSKMWICIKCSYaYNRLWLQTCEMCEAKAE 672
Cdd:pfam00641    1 REGDWDCSKCLV-QNFATSTKCVACQAPKP 29
 
Name Accession Description Interval E-value
CysPc smart00230
Calpain-like thiol protease family; Calpain-like thiol protease family (peptidase family C2). ...
1001-1328 1.08e-140

Calpain-like thiol protease family; Calpain-like thiol protease family (peptidase family C2). Calcium activated neutral protease (large subunit).


Pssm-ID: 128526  Cd Length: 318  Bit Score: 435.60  E-value: 1.08e-140
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090    1001 WQNIIQYCRDNSELFVDDSFPPAPKSLYYNPASGagegnPVVQWRRPHEINCDggayPPWAVFRTPlPSDICQGVLGNCW 1080
Cdd:smart00230    1 YEALRQYCKESGTLFEDPLFPANNGSLFFSQRQR-----KFVVWKRPHEIFEN----PPFIVGGAS-RTDICQGVLGDCW 70
                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090    1081 LLSALAVLAEREDLVKEVLV-TKEIC--GQGAYQVRLCKDGKWTTVLVDDLLPCDKRGHLVYSQAKRKQLWVPLIEKAVA 1157
Cdd:smart00230   71 LLAALASLTLREKLLDRVIPhDQEFSenYAGIFHFRFWRFGKWVDVVIDDRLPTYNGELVFMHSNSRNEFWSALLEKAYA 150
                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090    1158 KIHGCYEALVSGRAIEGLATLTGAPCESIPLQAsslPMPSEDELDKDLIWAQLLSsrcvrFLMGASCGGGNmKVDEEEYQ 1237
Cdd:smart00230  151 KLNGCYEALKGGSTTEALEDLTGGVAESIDLKE---ASKDPDNLFEDLFKAFERG-----SLMGCSIGAGT-AVEEEEQK 221
                           250       260       270       280       290       300       310       320
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090    1238 QKGLRPRHAYSVLDVKDIQGHR--LLKLRNPWGHYSWRGDWSDDSSLWT---DDLRDALMPHGASEGVFWISFEDVLNYF 1312
Cdd:smart00230  222 DCGLVKGHAYSVTDVREVQGRRqeLLRLRNPWGQVEWNGPWSDDSPEWRsvsASEKKNLGLTFDDDGEFWMSFEDFLRHF 301
                           330
                    ....*....|....*.
gi 55584090    1313 DCIDICKVRSGWNEVR 1328
Cdd:smart00230  302 DKVEICNLNPDSLEER 317
CysPc cd00044
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. ...
1003-1319 8.91e-130

Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.


Pssm-ID: 238004 [Multi-domain]  Cd Length: 315  Bit Score: 405.95  E-value: 8.91e-130
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090 1003 NIIQYCRDNSELFVDDSFPPAPKSLYYNPASGAGEGNPVVQWRRPHEINCDGGAYPPWAVFRTPLPSDICQGVLGNCWLL 1082
Cdd:cd00044    1 TLLQICLLSGVLFEDPDFPPNDSSLGFDDSLSNGQPKKVIEWKRPSEIFADDGNSNPRLFVNGASPSDVCQGILGDCWFL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090 1083 SALAVLAEREDLVKEVLVTK---EICGQGAYQVRLCKDGKWTTVLVDDLLPCDKRGHLVYSQAKRKQLWVPLIEKAVAKI 1159
Cdd:cd00044   81 AALAALAERPELLKRVIPPDqsfEENYAGIYHFRFWKNGEWVEVVIDDRLPTSNGGLLFMHSRDRNELWVALLEKAYAKL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090 1160 HGCYEALVSGRAIEGLATLTGAPCESIPLQASSLPmpsedeLDKDLIWAQLLSSRCVRFLMGASCGGGNMkvdEEEYQQK 1239
Cdd:cd00044  161 HGSYEALVGGNTAEALEDLTGGPTERIDLKSADAS------SGDNDLFALLLSFLQGGSLIGCSTGSRSE---EEARTAN 231
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090 1240 GLRPRHAYSVLDVKDIQ--GHRLLKLRNPWGHYSWRGDWSDDSSLW--TDDLRDALMPHGASEGVFWISFEDVLNYFDCI 1315
Cdd:cd00044  232 GLVKGHAYSVLDVREVQeeGLRLLRLRNPWGVGEWWGGWSDDSSEWwvIDAERKKLLLSGKDDGEFWMSFEDFLRNFDGL 311

                 ....
gi 55584090 1316 DICK 1319
Cdd:cd00044  312 YVCN 315
Peptidase_C2 pfam00648
Calpain family cysteine protease;
1015-1319 1.53e-117

Calpain family cysteine protease;


Pssm-ID: 459889 [Multi-domain]  Cd Length: 295  Bit Score: 371.83  E-value: 1.53e-117
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090   1015 FVDDSFPPAPKSLYYNPASgagEGNPVVQWRRPHEINCDggayppwAVFRT--PLPSDICQGVLGNCWLLSALAVLAERE 1092
Cdd:pfam00648    1 FEDPEFPADDSSLGYPPSP---PPPRGVEWKRPKEICSN-------PQFIVdgASRFDICQGELGDCWLLAAIASLTLNP 70
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090   1093 DLVKEVLVTK---EICGQGAYQVRLCKDGKWTTVLVDDLLPCdKRGHLVYSQ-AKRKQLWVPLIEKAVAKIHGCYEALVS 1168
Cdd:pfam00648   71 KLLERVVPPDqsfEENYAGIFHFRFWRFGEWVDVVIDDRLPT-RNGKLLFVHsRDKNEFWSALLEKAYAKLHGSYEALKG 149
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090   1169 GRAIEGLATLTGAPCESIPLQasslpmpsedELDKDLiWAQLLSSRCVRFLMGASCGGGNMKvDEEEYQQKGLRPRHAYS 1248
Cdd:pfam00648  150 GSTSEALEDFTGGVAESYDLK----------EPPPNL-FEILLKALERGSLMGCSIDATSAA-EEEARTPNGLVKGHAYS 217
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 55584090   1249 VLDVKDI----QGHRLLKLRNPWGHYSWRGDWSDDSSLW---TDDLRDALMPHGASEGVFWISFEDVLNYFDCIDICK 1319
Cdd:pfam00648  218 VTGVRKVnlkgGKVRLIRLRNPWGEVEWNGAWSDGSPEWqtvSPEEKEELGLTKKDDGEFWMSFEDFLKYFTDLEICN 295
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
927-954 3.11e-06

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 45.04  E-value: 3.11e-06
                           10        20
                   ....*....|....*....|....*...
gi 55584090    927 STKKWQCPACTYDNCAASVVCDICSSPR 954
Cdd:pfam00641    1 REGDWDCSKCLVQNFATSTKCVACQAPK 28
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
6-34 5.45e-06

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 44.27  E-value: 5.45e-06
                           10        20
                   ....*....|....*....|....*....
gi 55584090      6 SVLQWSCTKCNTINPTESLKCFNCGTVRK 34
Cdd:pfam00641    1 REGDWDCSKCLVQNFATSTKCVACQAPKP 29
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
704-731 1.49e-05

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 43.11  E-value: 1.49e-05
                           10        20
                   ....*....|....*....|....*...
gi 55584090    704 RDEPWTCKKCTLVNYSTAMACVVCGGSK 731
Cdd:pfam00641    1 REGDWDCSKCLVQNFATSTKCVACQAPK 28
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
747-774 1.73e-05

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 43.11  E-value: 1.73e-05
                           10        20
                   ....*....|....*....|....*...
gi 55584090    747 EFWTCSHCTLKNSLHSPVCSACKSHRQP 774
Cdd:pfam00641    3 GDWDCSKCLVQNFATSTKCVACQAPKPD 30
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
135-164 3.91e-05

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 41.95  E-value: 3.91e-05
                           10        20        30
                   ....*....|....*....|....*....|
gi 55584090    135 LNRRWVCHACGTDNSSVTWHCLICDTVSYL 164
Cdd:pfam00641    1 REGDWDCSKCLVQNFATSTKCVACQAPKPD 30
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
643-672 4.97e-04

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 38.87  E-value: 4.97e-04
                           10        20        30
                   ....*....|....*....|....*....|
gi 55584090    643 RSKMWICIKCSYaYNRLWLQTCEMCEAKAE 672
Cdd:pfam00641    1 REGDWDCSKCLV-QNFATSTKCVACQAPKP 29
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
930-953 8.43e-04

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 38.07  E-value: 8.43e-04
                            10        20
                    ....*....|....*....|....
gi 55584090     930 KWQCPACTYDNCAASVVCDICSSP 953
Cdd:smart00547    2 DWECPACTFLNFASRSKCFACGAP 25
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
9-32 5.28e-03

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 35.76  E-value: 5.28e-03
                            10        20
                    ....*....|....*....|....
gi 55584090       9 QWSCTKCNTINPTESLKCFNCGTV 32
Cdd:smart00547    2 DWECPACTFLNFASRSKCFACGAP 25
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
708-730 7.24e-03

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 35.37  E-value: 7.24e-03
                            10        20
                    ....*....|....*....|...
gi 55584090     708 WTCKKCTLVNYSTAMACVVCGGS 730
Cdd:smart00547    3 WECPACTFLNFASRSKCFACGAP 25
 
Name Accession Description Interval E-value
CysPc smart00230
Calpain-like thiol protease family; Calpain-like thiol protease family (peptidase family C2). ...
1001-1328 1.08e-140

Calpain-like thiol protease family; Calpain-like thiol protease family (peptidase family C2). Calcium activated neutral protease (large subunit).


Pssm-ID: 128526  Cd Length: 318  Bit Score: 435.60  E-value: 1.08e-140
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090    1001 WQNIIQYCRDNSELFVDDSFPPAPKSLYYNPASGagegnPVVQWRRPHEINCDggayPPWAVFRTPlPSDICQGVLGNCW 1080
Cdd:smart00230    1 YEALRQYCKESGTLFEDPLFPANNGSLFFSQRQR-----KFVVWKRPHEIFEN----PPFIVGGAS-RTDICQGVLGDCW 70
                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090    1081 LLSALAVLAEREDLVKEVLV-TKEIC--GQGAYQVRLCKDGKWTTVLVDDLLPCDKRGHLVYSQAKRKQLWVPLIEKAVA 1157
Cdd:smart00230   71 LLAALASLTLREKLLDRVIPhDQEFSenYAGIFHFRFWRFGKWVDVVIDDRLPTYNGELVFMHSNSRNEFWSALLEKAYA 150
                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090    1158 KIHGCYEALVSGRAIEGLATLTGAPCESIPLQAsslPMPSEDELDKDLIWAQLLSsrcvrFLMGASCGGGNmKVDEEEYQ 1237
Cdd:smart00230  151 KLNGCYEALKGGSTTEALEDLTGGVAESIDLKE---ASKDPDNLFEDLFKAFERG-----SLMGCSIGAGT-AVEEEEQK 221
                           250       260       270       280       290       300       310       320
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090    1238 QKGLRPRHAYSVLDVKDIQGHR--LLKLRNPWGHYSWRGDWSDDSSLWT---DDLRDALMPHGASEGVFWISFEDVLNYF 1312
Cdd:smart00230  222 DCGLVKGHAYSVTDVREVQGRRqeLLRLRNPWGQVEWNGPWSDDSPEWRsvsASEKKNLGLTFDDDGEFWMSFEDFLRHF 301
                           330
                    ....*....|....*.
gi 55584090    1313 DCIDICKVRSGWNEVR 1328
Cdd:smart00230  302 DKVEICNLNPDSLEER 317
CysPc cd00044
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. ...
1003-1319 8.91e-130

Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.


Pssm-ID: 238004 [Multi-domain]  Cd Length: 315  Bit Score: 405.95  E-value: 8.91e-130
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090 1003 NIIQYCRDNSELFVDDSFPPAPKSLYYNPASGAGEGNPVVQWRRPHEINCDGGAYPPWAVFRTPLPSDICQGVLGNCWLL 1082
Cdd:cd00044    1 TLLQICLLSGVLFEDPDFPPNDSSLGFDDSLSNGQPKKVIEWKRPSEIFADDGNSNPRLFVNGASPSDVCQGILGDCWFL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090 1083 SALAVLAEREDLVKEVLVTK---EICGQGAYQVRLCKDGKWTTVLVDDLLPCDKRGHLVYSQAKRKQLWVPLIEKAVAKI 1159
Cdd:cd00044   81 AALAALAERPELLKRVIPPDqsfEENYAGIYHFRFWKNGEWVEVVIDDRLPTSNGGLLFMHSRDRNELWVALLEKAYAKL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090 1160 HGCYEALVSGRAIEGLATLTGAPCESIPLQASSLPmpsedeLDKDLIWAQLLSSRCVRFLMGASCGGGNMkvdEEEYQQK 1239
Cdd:cd00044  161 HGSYEALVGGNTAEALEDLTGGPTERIDLKSADAS------SGDNDLFALLLSFLQGGSLIGCSTGSRSE---EEARTAN 231
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090 1240 GLRPRHAYSVLDVKDIQ--GHRLLKLRNPWGHYSWRGDWSDDSSLW--TDDLRDALMPHGASEGVFWISFEDVLNYFDCI 1315
Cdd:cd00044  232 GLVKGHAYSVLDVREVQeeGLRLLRLRNPWGVGEWWGGWSDDSSEWwvIDAERKKLLLSGKDDGEFWMSFEDFLRNFDGL 311

                 ....
gi 55584090 1316 DICK 1319
Cdd:cd00044  312 YVCN 315
Peptidase_C2 pfam00648
Calpain family cysteine protease;
1015-1319 1.53e-117

Calpain family cysteine protease;


Pssm-ID: 459889 [Multi-domain]  Cd Length: 295  Bit Score: 371.83  E-value: 1.53e-117
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090   1015 FVDDSFPPAPKSLYYNPASgagEGNPVVQWRRPHEINCDggayppwAVFRT--PLPSDICQGVLGNCWLLSALAVLAERE 1092
Cdd:pfam00648    1 FEDPEFPADDSSLGYPPSP---PPPRGVEWKRPKEICSN-------PQFIVdgASRFDICQGELGDCWLLAAIASLTLNP 70
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090   1093 DLVKEVLVTK---EICGQGAYQVRLCKDGKWTTVLVDDLLPCdKRGHLVYSQ-AKRKQLWVPLIEKAVAKIHGCYEALVS 1168
Cdd:pfam00648   71 KLLERVVPPDqsfEENYAGIFHFRFWRFGEWVDVVIDDRLPT-RNGKLLFVHsRDKNEFWSALLEKAYAKLHGSYEALKG 149
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55584090   1169 GRAIEGLATLTGAPCESIPLQasslpmpsedELDKDLiWAQLLSSRCVRFLMGASCGGGNMKvDEEEYQQKGLRPRHAYS 1248
Cdd:pfam00648  150 GSTSEALEDFTGGVAESYDLK----------EPPPNL-FEILLKALERGSLMGCSIDATSAA-EEEARTPNGLVKGHAYS 217
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 55584090   1249 VLDVKDI----QGHRLLKLRNPWGHYSWRGDWSDDSSLW---TDDLRDALMPHGASEGVFWISFEDVLNYFDCIDICK 1319
Cdd:pfam00648  218 VTGVRKVnlkgGKVRLIRLRNPWGEVEWNGAWSDGSPEWqtvSPEEKEELGLTKKDDGEFWMSFEDFLKYFTDLEICN 295
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
927-954 3.11e-06

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 45.04  E-value: 3.11e-06
                           10        20
                   ....*....|....*....|....*...
gi 55584090    927 STKKWQCPACTYDNCAASVVCDICSSPR 954
Cdd:pfam00641    1 REGDWDCSKCLVQNFATSTKCVACQAPK 28
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
6-34 5.45e-06

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 44.27  E-value: 5.45e-06
                           10        20
                   ....*....|....*....|....*....
gi 55584090      6 SVLQWSCTKCNTINPTESLKCFNCGTVRK 34
Cdd:pfam00641    1 REGDWDCSKCLVQNFATSTKCVACQAPKP 29
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
704-731 1.49e-05

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 43.11  E-value: 1.49e-05
                           10        20
                   ....*....|....*....|....*...
gi 55584090    704 RDEPWTCKKCTLVNYSTAMACVVCGGSK 731
Cdd:pfam00641    1 REGDWDCSKCLVQNFATSTKCVACQAPK 28
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
747-774 1.73e-05

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 43.11  E-value: 1.73e-05
                           10        20
                   ....*....|....*....|....*...
gi 55584090    747 EFWTCSHCTLKNSLHSPVCSACKSHRQP 774
Cdd:pfam00641    3 GDWDCSKCLVQNFATSTKCVACQAPKPD 30
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
135-164 3.91e-05

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 41.95  E-value: 3.91e-05
                           10        20        30
                   ....*....|....*....|....*....|
gi 55584090    135 LNRRWVCHACGTDNSSVTWHCLICDTVSYL 164
Cdd:pfam00641    1 REGDWDCSKCLVQNFATSTKCVACQAPKPD 30
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
643-672 4.97e-04

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 38.87  E-value: 4.97e-04
                           10        20        30
                   ....*....|....*....|....*....|
gi 55584090    643 RSKMWICIKCSYaYNRLWLQTCEMCEAKAE 672
Cdd:pfam00641    1 REGDWDCSKCLV-QNFATSTKCVACQAPKP 29
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
930-953 8.43e-04

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 38.07  E-value: 8.43e-04
                            10        20
                    ....*....|....*....|....
gi 55584090     930 KWQCPACTYDNCAASVVCDICSSP 953
Cdd:smart00547    2 DWECPACTFLNFASRSKCFACGAP 25
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
9-32 5.28e-03

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 35.76  E-value: 5.28e-03
                            10        20
                    ....*....|....*....|....
gi 55584090       9 QWSCTKCNTINPTESLKCFNCGTV 32
Cdd:smart00547    2 DWECPACTFLNFASRSKCFACGAP 25
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
708-730 7.24e-03

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 35.37  E-value: 7.24e-03
                            10        20
                    ....*....|....*....|...
gi 55584090     708 WTCKKCTLVNYSTAMACVVCGGS 730
Cdd:smart00547    3 WECPACTFLNFASRSKCFACGAP 25
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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