|
Name |
Accession |
Description |
Interval |
E-value |
| 2A0125 |
TIGR00901 |
AmpG-like permease; [Cellular processes, Adaptations to atypical conditions] |
25-373 |
1.72e-141 |
|
AmpG-like permease; [Cellular processes, Adaptations to atypical conditions]
Pssm-ID: 273329 [Multi-domain] Cd Length: 356 Bit Score: 407.93 E-value: 1.72e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 25 GLPLFVLSQMLPVWLTDKHLSIELIGAVTGVMLPYGLKFLWAPLLDRYFPSFLGRRRSWMLLSQVALLILLYIISLFDPL 104
Cdd:TIGR00901 1 GLPLGLVGNTLPYWLRSKNVSLKTIGFFSLVGLPYSLKFLWSPLVDTVYLPFFGRRRSWLVLTQVLLLSLLLILSFLVPS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 105 TQLGTVANIALLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPGGLSLYLAAIYP--------WETVF 176
Cdd:TIGR00901 81 TDLPLLAGLAFLIAFFSATQDIALDAWRLEILSDEELGYGSTIYIVGYRAGMLLSGSLALVLASPEFantglitlWGYIF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 177 LWTALCMLAGIFMTLFLAKEPKIDMQQTNqPFYQAFWIPLQEFFQRKGVIQAIGFLLFLFLYKFGDSFATTLQTKFIYDM 256
Cdd:TIGR00901 161 FWTALLILPGLLVTLFLAKEPQEDASVPK-PLTQAVLKPIREFFQRKNMIQALLLLLLIVLYKLGDSAATVLTTLFLLDM 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 257 GFSKEDIAIVVKSTALWSSILSGLAGGMIMLKLGINRALWLFGLVQMVTIGGFIWLAAFGHFDVITSAELWKLGVVIAAE 336
Cdd:TIGR00901 240 GFSKEEIALVAKINGLLGAILGGLIGGIIMQPLNILYALLLFGIVQALTNAGFVWLASNGHHDGITFPHLLMLFLTITLE 319
|
330 340 350
....*....|....*....|....*....|....*..
gi 1175225 337 YIGVGLGTAAFVAFMARESNPLYTATQLALFTSLSAL 373
Cdd:TIGR00901 320 AVTGGLGTVAFVAFLSKLSNPKFGATQMALLSSLSAL 356
|
|
| MFS_AmpG_like |
cd17486 |
AmpG and similar transporters of the Major Facilitator Superfamily; AmpG acts as an inner ... |
19-412 |
2.45e-120 |
|
AmpG and similar transporters of the Major Facilitator Superfamily; AmpG acts as an inner membrane permease in the beta-lactamase induction system and in peptidoglycan recycling. It transports meuropeptide from the periplasm into the cytosol in gram-negative bacteria, which is essential for the induction of the ampC encoding beta-lactamase. The AmpG family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 341039 [Multi-domain] Cd Length: 387 Bit Score: 355.37 E-value: 2.45e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 19 FTGFNSGLPLFVLSQMLPVWLTDKHLSIELIGAVTGVMLPYGLKFLWAPLLDRYFPSFLGRRRSWMLLSQVALLILLYII 98
Cdd:cd17486 3 LLGFASGLPYLLTGTTLQAWLKEAGVDLDTIGLFSLVGLPYSLKFLWAPLVDRYSTPFLGRRRGWILLTQILLMAALIAL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 99 SLFDPLTQLGTVANIALLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPGGLSLYLAAIYPWETVFLW 178
Cdd:cd17486 83 AFLDPFTNLVLSALLFLLVAFFSATQDIAIDAYRIEALEDKEQGAGAGVRVNGYRIGMLVAGAGALYLADSLSWSAVYLI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 179 TALCMLAGIFMTLFLAKEPKIDmqQTNQPFYQAFWIPLQEFFQRKGVIQAIGFLLFLFLYKFGDSFATTLQTKFIYDMGF 258
Cdd:cd17486 163 MAALMGPGILATLFAPEPPRTD--PPANSLSETVVAFFAPFKDFFGQPGALLILAFILLYKLGDAMLGAMATPFLLDLGF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 259 SKEDIAIVVKSTALWSSILSGLAGGMIMLKLGINRALWLFGLVQMVTIGGFIWLAAFGHfdvitsaELWKLGVVIAAEYI 338
Cdd:cd17486 241 TKTEIGAVYKTVGLIATIVGGLLGGFLMSRLGLKRSLWLFGILQALSNLGFIYLAHAGP-------NLTLLVAAVAVENF 313
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1175225 339 GVGLGTAAFVAFMARESNPLYTATQLALFTSLSALPSKVLGILSGYVVGAVGYYQYFWFCLFLAIPGMLCLFWV 412
Cdd:cd17486 314 GGGLGTTAFVAYLMSLCNGEFTATQYALLSSLMALGRMVLGAPSGWLAEALGWTGFFLLTTLAAIPGLLLLLKV 387
|
|
| ampG |
PRK11010 |
muropeptide MFS transporter AmpG; |
1-410 |
8.04e-78 |
|
muropeptide MFS transporter AmpG;
Pssm-ID: 182898 [Multi-domain] Cd Length: 491 Bit Score: 249.56 E-value: 8.04e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 1 MSNSLSSQIFTRKMLICAFTGFNSGLPLFVLSQMLPVWLTDKHLSIELIGAVTGVMLPYGLKFLWAPLLDRYFPSFLGRR 80
Cdd:PRK11010 1 MSSQYLRIFQQPNSAILLILGFASGLPLALTSGTLQAWMTVENIDLKTIGFFSLVGQAYVFKFLWSPLMDRYTPPFLGRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 81 RSWMLLSQVALLILLYIISLFDPLTQLGTVANIALLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPG 160
Cdd:PRK11010 81 RGWLLATQLLLLVAIAAMGFLEPGTQLRWLAALAVVIAFCSASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLAMLVSG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 161 GLSLYLAAIY-PWETVFLWTALCMLAGIFMTLfLAKEPKIDmQQTNQPFYQAFWIPLQEFFQRKgviQAIGFLLFLFLYK 239
Cdd:PRK11010 161 GLALWLADRYlGWQGMYWLMAALLIPCIIATL-LAPEPTDT-IPVPKTLEQAVVAPLRDFFGRN---NAWLILLLIVLYK 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 240 FGDSFATTLQTKF-IYDMGFSKEDIAIVVKSTALWSSILSGLAGGMIMLKLGINRALWLFGLVQMVTIGGFiWLAAfghf 318
Cdd:PRK11010 236 LGDAFAMSLTTTFlIRGVGFDAGEVGLVNKTLGLLATIVGALYGGILMQRLSLFRALMIFGILQGVSNAGY-WLLS---- 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 319 dvITSAELWKLGVVIAAEYIGVGLGTAAFVAFMARESNPLYTATQLALFTSLSALPSKVLGILSGYVVGAVGYYQYFWFC 398
Cdd:PRK11010 311 --ITDKNLYSMGAAVFFENLCGGMGTAAFVALLMTLCNKSFSATQFALLSALSAVGRVYVGPVAGWFVEAHGWPTFYLFS 388
|
410
....*....|..
gi 1175225 399 LFLAIPGMLCLF 410
Cdd:PRK11010 389 VAAAVPGLLLLL 400
|
|
| MFS_1 |
pfam07690 |
Major Facilitator Superfamily; |
18-375 |
8.04e-07 |
|
Major Facilitator Superfamily;
Pssm-ID: 429598 [Multi-domain] Cd Length: 344 Bit Score: 50.49 E-value: 8.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 18 AFTGFNSGLPLFVLSQMLPVWLT-DKHLSIELIG-AVTGVMLPYGL-KFLWAPLLDRYfpsflgRRRSWMLLSQVALLIL 94
Cdd:pfam07690 2 FLAAFLAALGRSLLGPALPLLLAeDLGISPTEIGlLLTLFSLGYALaQPLAGRLSDRF------GRRRVLLIGLLLFALG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 95 LYIISLFDPLTQLGTVAniaLLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPGGLSLYLAAIYPWET 174
Cdd:pfam07690 76 LLLLLFASSLWLLLVLR---VLQGLGAGALFPAALALIADWFPPEERGRALGLVSAGFGLGAALGPLLGGLLASLFGWRA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 175 VFLWTALCMLAGIFMTLFLAKEPKIDMQQTNQPFYQAFWIPLQEFFQRKGVIQAIGFLLFLFLYkfgdSFATTLQTKFIY 254
Cdd:pfam07690 153 AFLILAILSLLAAVLLLLPRPPPESKRPKPAEEARLSLIVAWKALLRDPVLWLLLALLLFGFAF----FGLLTYLPLYQE 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 255 DMGFSKEDIAIVVKSTALwSSILSGLAGGMIMLKLGINRALWLFGLVQMVTIGGFIWLAAFGHFDVITsaelwklgVVIA 334
Cdd:pfam07690 229 VLGLSALLAGLLLGLGGL-LGAIGRLLLGRLSDRLGRRRRLLLALLLLILAALGLLLLSLTLSSLWLL--------LALL 299
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 1175225 335 AEYIGVGLGTAAFVAFMARESNPLYTATQLALFTSLSALPS 375
Cdd:pfam07690 300 LLGFGFGLVFPALNALVSDLAPKEERGTASGLYNTAGSLGG 340
|
|
| AraJ |
COG2814 |
Predicted arabinose efflux permease AraJ, MFS family [Carbohydrate transport and metabolism]; |
14-373 |
5.41e-05 |
|
Predicted arabinose efflux permease AraJ, MFS family [Carbohydrate transport and metabolism];
Pssm-ID: 442063 [Multi-domain] Cd Length: 348 Bit Score: 44.96 E-value: 5.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 14 MLICAFTGFNSGLPLFVLSQMLPVWLTDKHLSIELIGAVTGV-MLPYGL-KFLWAPLLDRYfpsflGRRRSwMLLSQVAL 91
Cdd:COG2814 12 LLALALGAFLSGLGIGIVLPALPLIAADLGASPAQAGLVVTAyLLGAALgAPLAGRLADRF-----GRRRV-LLLGLLLF 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 92 LILLYIISLFDPLTQLGTVAniaLLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPGGLSLYLAAIYP 171
Cdd:COG2814 86 ALGSLLCALAPSLWLLLAAR---FLQGLGAGALFPAALALIADLVPPERRGRALGLLGAGLGLGPALGPLLGGLLADLFG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 172 WETVFLWTALCMLAGIFMTLFLAKEPKIDMQqtnqpfyQAFWIPLQEFFQRKGVIQAIGFLLFLFLYKFGdsFATTLQTK 251
Cdd:COG2814 163 WRWVFLVNAVLALLALLLLLRLLPESRPAAR-------ARLRGSLRELLRRPRLLLLLLLAFLLGFGFFA--LFTYLPLY 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 252 FIYDMGFSKEDIAIVVKSTALwSSILSGLAGGMIMLKLGINRALWLFGLVQMVTIGGFIWLAAFghfdvitsaelWKLGV 331
Cdd:COG2814 234 LQEVLGLSASAAGLLLALFGL-GGVLGALLAGRLADRFGRRRLLLIGLLLLALGLLLLALAGSL-----------WLLLL 301
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1175225 332 VIAAEYIGVGLGTAAFVAFMARESNPLYTATQLALFTSLSAL 373
Cdd:COG2814 302 ALFLLGFGFGLLFPLLQALVAELAPPEARGRASGLYNSAFFL 343
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| 2A0125 |
TIGR00901 |
AmpG-like permease; [Cellular processes, Adaptations to atypical conditions] |
25-373 |
1.72e-141 |
|
AmpG-like permease; [Cellular processes, Adaptations to atypical conditions]
Pssm-ID: 273329 [Multi-domain] Cd Length: 356 Bit Score: 407.93 E-value: 1.72e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 25 GLPLFVLSQMLPVWLTDKHLSIELIGAVTGVMLPYGLKFLWAPLLDRYFPSFLGRRRSWMLLSQVALLILLYIISLFDPL 104
Cdd:TIGR00901 1 GLPLGLVGNTLPYWLRSKNVSLKTIGFFSLVGLPYSLKFLWSPLVDTVYLPFFGRRRSWLVLTQVLLLSLLLILSFLVPS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 105 TQLGTVANIALLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPGGLSLYLAAIYP--------WETVF 176
Cdd:TIGR00901 81 TDLPLLAGLAFLIAFFSATQDIALDAWRLEILSDEELGYGSTIYIVGYRAGMLLSGSLALVLASPEFantglitlWGYIF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 177 LWTALCMLAGIFMTLFLAKEPKIDMQQTNqPFYQAFWIPLQEFFQRKGVIQAIGFLLFLFLYKFGDSFATTLQTKFIYDM 256
Cdd:TIGR00901 161 FWTALLILPGLLVTLFLAKEPQEDASVPK-PLTQAVLKPIREFFQRKNMIQALLLLLLIVLYKLGDSAATVLTTLFLLDM 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 257 GFSKEDIAIVVKSTALWSSILSGLAGGMIMLKLGINRALWLFGLVQMVTIGGFIWLAAFGHFDVITSAELWKLGVVIAAE 336
Cdd:TIGR00901 240 GFSKEEIALVAKINGLLGAILGGLIGGIIMQPLNILYALLLFGIVQALTNAGFVWLASNGHHDGITFPHLLMLFLTITLE 319
|
330 340 350
....*....|....*....|....*....|....*..
gi 1175225 337 YIGVGLGTAAFVAFMARESNPLYTATQLALFTSLSAL 373
Cdd:TIGR00901 320 AVTGGLGTVAFVAFLSKLSNPKFGATQMALLSSLSAL 356
|
|
| MFS_AmpG_like |
cd17486 |
AmpG and similar transporters of the Major Facilitator Superfamily; AmpG acts as an inner ... |
19-412 |
2.45e-120 |
|
AmpG and similar transporters of the Major Facilitator Superfamily; AmpG acts as an inner membrane permease in the beta-lactamase induction system and in peptidoglycan recycling. It transports meuropeptide from the periplasm into the cytosol in gram-negative bacteria, which is essential for the induction of the ampC encoding beta-lactamase. The AmpG family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 341039 [Multi-domain] Cd Length: 387 Bit Score: 355.37 E-value: 2.45e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 19 FTGFNSGLPLFVLSQMLPVWLTDKHLSIELIGAVTGVMLPYGLKFLWAPLLDRYFPSFLGRRRSWMLLSQVALLILLYII 98
Cdd:cd17486 3 LLGFASGLPYLLTGTTLQAWLKEAGVDLDTIGLFSLVGLPYSLKFLWAPLVDRYSTPFLGRRRGWILLTQILLMAALIAL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 99 SLFDPLTQLGTVANIALLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPGGLSLYLAAIYPWETVFLW 178
Cdd:cd17486 83 AFLDPFTNLVLSALLFLLVAFFSATQDIAIDAYRIEALEDKEQGAGAGVRVNGYRIGMLVAGAGALYLADSLSWSAVYLI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 179 TALCMLAGIFMTLFLAKEPKIDmqQTNQPFYQAFWIPLQEFFQRKGVIQAIGFLLFLFLYKFGDSFATTLQTKFIYDMGF 258
Cdd:cd17486 163 MAALMGPGILATLFAPEPPRTD--PPANSLSETVVAFFAPFKDFFGQPGALLILAFILLYKLGDAMLGAMATPFLLDLGF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 259 SKEDIAIVVKSTALWSSILSGLAGGMIMLKLGINRALWLFGLVQMVTIGGFIWLAAFGHfdvitsaELWKLGVVIAAEYI 338
Cdd:cd17486 241 TKTEIGAVYKTVGLIATIVGGLLGGFLMSRLGLKRSLWLFGILQALSNLGFIYLAHAGP-------NLTLLVAAVAVENF 313
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1175225 339 GVGLGTAAFVAFMARESNPLYTATQLALFTSLSALPSKVLGILSGYVVGAVGYYQYFWFCLFLAIPGMLCLFWV 412
Cdd:cd17486 314 GGGLGTTAFVAYLMSLCNGEFTATQYALLSSLMALGRMVLGAPSGWLAEALGWTGFFLLTTLAAIPGLLLLLKV 387
|
|
| ampG |
PRK11010 |
muropeptide MFS transporter AmpG; |
1-410 |
8.04e-78 |
|
muropeptide MFS transporter AmpG;
Pssm-ID: 182898 [Multi-domain] Cd Length: 491 Bit Score: 249.56 E-value: 8.04e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 1 MSNSLSSQIFTRKMLICAFTGFNSGLPLFVLSQMLPVWLTDKHLSIELIGAVTGVMLPYGLKFLWAPLLDRYFPSFLGRR 80
Cdd:PRK11010 1 MSSQYLRIFQQPNSAILLILGFASGLPLALTSGTLQAWMTVENIDLKTIGFFSLVGQAYVFKFLWSPLMDRYTPPFLGRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 81 RSWMLLSQVALLILLYIISLFDPLTQLGTVANIALLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPG 160
Cdd:PRK11010 81 RGWLLATQLLLLVAIAAMGFLEPGTQLRWLAALAVVIAFCSASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLAMLVSG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 161 GLSLYLAAIY-PWETVFLWTALCMLAGIFMTLfLAKEPKIDmQQTNQPFYQAFWIPLQEFFQRKgviQAIGFLLFLFLYK 239
Cdd:PRK11010 161 GLALWLADRYlGWQGMYWLMAALLIPCIIATL-LAPEPTDT-IPVPKTLEQAVVAPLRDFFGRN---NAWLILLLIVLYK 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 240 FGDSFATTLQTKF-IYDMGFSKEDIAIVVKSTALWSSILSGLAGGMIMLKLGINRALWLFGLVQMVTIGGFiWLAAfghf 318
Cdd:PRK11010 236 LGDAFAMSLTTTFlIRGVGFDAGEVGLVNKTLGLLATIVGALYGGILMQRLSLFRALMIFGILQGVSNAGY-WLLS---- 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 319 dvITSAELWKLGVVIAAEYIGVGLGTAAFVAFMARESNPLYTATQLALFTSLSALPSKVLGILSGYVVGAVGYYQYFWFC 398
Cdd:PRK11010 311 --ITDKNLYSMGAAVFFENLCGGMGTAAFVALLMTLCNKSFSATQFALLSALSAVGRVYVGPVAGWFVEAHGWPTFYLFS 388
|
410
....*....|..
gi 1175225 399 LFLAIPGMLCLF 410
Cdd:PRK11010 389 VAAAVPGLLLLL 400
|
|
| ampG |
PRK11902 |
muropeptide transporter; Reviewed |
21-410 |
1.15e-74 |
|
muropeptide transporter; Reviewed
Pssm-ID: 183369 [Multi-domain] Cd Length: 402 Bit Score: 238.60 E-value: 1.15e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 21 GFNSGLPLFVLSQMLPVWLTDKHLSIELIGAVTGVMLPYGLKFLWAPLLDRYFPSFLGRRRSWMLLSQVALLILLYIISL 100
Cdd:PRK11902 8 GFASGLPLALTSGTLQAWMTVEGLDIQTIGFFSLVGQAYIFKFLWAPLMDRYTPPLLGRRRGWLLLTQVGLAASIAAMAF 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 101 FDPLTQLGTVANIALLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPGGLSLYLA-AIYPWETVFLWT 179
Cdd:PRK11902 88 CPPHAALWPLAGLAVLVAFLSASQDIVFDAYSTDVLHPEERGAGAAVKVLGYRLAMLVSGGLALWLAdRVLGWGNTYLLM 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 180 ALCMLAGIfMTLFLAKEPKIDmQQTNQPFYQAFWIPLQEFFQRKGviqAIGFLLFLFLYKFGDSFATTLQTKF-IYDMGF 258
Cdd:PRK11902 168 AGLMLAGA-LTTLWAPEPEVP-ARPPRSLGEAVVGPLRDFFSRRG---AWALLLLIVLYKLGDAFAGSLSTTFlIRGAGF 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 259 SKEDIAIVVKSTALWSSILSGLAGGMIMLKLGINRALWLFGLVQMVTIGGFiWLAAfghfdvITSAELWKLGVVIAAEYI 338
Cdd:PRK11902 243 SAGEVGIVNKTLGLAATIVGALAGGTLMVRLGLYRSLMLFGVLQAVSNLGY-WVLA------VTPKHLWTMALAIGIENL 315
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1175225 339 GVGLGTAAFVAFMARESNPLYTATQLALFTSLSALPSKVLGILSGYVVGAVGYYQYFWFCLFLAIPGMLCLF 410
Cdd:PRK11902 316 CGGMGTAAFVALLMALCNRSFSATQYALLSALASVGRVYVGPTSGYLVEAYGWPGFYLMTVVIALPGLALLW 387
|
|
| MFS_MFSD3 |
cd17485 |
Major facilitator superfamily domain containing 3 protein; Major facilitator superfamily ... |
25-407 |
5.70e-51 |
|
Major facilitator superfamily domain containing 3 protein; Major facilitator superfamily domain containing 3 protein (MFSD3) is a predicted acetyl-CoA transporter. As an atypical putative membrane-bound solute carrier (SLC), MFSD3 is most likely to be functionally active in the plasma membrane and not in any intracellular organelles. MFSD3 belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 341038 [Multi-domain] Cd Length: 386 Bit Score: 176.26 E-value: 5.70e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 25 GLPLFVLSQMLPVWLTDKHLSIELIGAVTGVMLPYGLKFLWAPLLDRYFPSFLGRRRSWMLLSQVALLILLYIISLFDPL 104
Cdd:cd17485 10 GLPYGFQSQALPVLLRSAGVSLTAIGLLKLLYLPWVLKFLWAPLVDRYGLPRLGRRRSWLLPTQLGLALLLLALAFLPPT 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 105 TQLGTVANIALLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPGGLSLYLAAIYPWETVFLWTALCML 184
Cdd:cd17485 90 TNLLAFLGLLFLLNLFSATQDIATDGLAVELLTPEERGLGNAAQVVGYKLGSLLGGGGLLWLYDLIGWQSLLLSLAALYL 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 185 AGIfMTLFLAKEPKIDMQQTNQPFYQAFWIPLQEFFQRKGVIQAIGfllFLFLYKFGDSFATTLQTKFIYDMGFSKEDIA 264
Cdd:cd17485 170 LLL-LPVLFLRELELPQQPPASERGAALKASLRAFLRRPGTRWLLL---FLLLYKLGEQGALAMLPPFLVDRGFSLSQIG 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 265 IVVKSTALWSSILSGLAGGMIMLKLGINRALWLFGLVQMVTIGGFIWLAAfghfdVITSAELWKLGVVIAAEYIGVGLGT 344
Cdd:cd17485 246 LLSGVGGSLVSIAGSLLGGYLLKRRGRRRLLLLGGLLRLLLLGLYTLLAL-----GGSGLNWVLLLASLALLHLVGGMIT 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1175225 345 AAFVAFMARESNPLYTATQLALFTSLSALPSKVLGILSGYVVGAVGYYQYFWFCLFLAIPGML 407
Cdd:cd17485 321 TALFTLMMDCSQQAQAGTDYTLLATVEVLGKLLFGSLAGFLADHLGYAAAFLLFAILSALSVL 383
|
|
| sider_RhtX_FptX |
TIGR02718 |
siderophore transporter, RhtX/FptX family; RhtX from Sinorhizobium meliloti 2011 and FptX from ... |
25-412 |
4.26e-21 |
|
siderophore transporter, RhtX/FptX family; RhtX from Sinorhizobium meliloti 2011 and FptX from Pseudomonas aeruginosa appear to be single polypeptide transporters, from the major facilitator family (see pfam07690) for import of siderophores as a means to import iron. This function was suggested by proximity to siderophore biosynthesis genes and then confirmed by study of knockout and heterologous expression phenotypes. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131765 Cd Length: 390 Bit Score: 94.19 E-value: 4.26e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 25 GLPLFVLSQMLPVWLTDKHLSIELIGAVTGVMLPYGLKFLWAPLLDRYFPSFLGRRRSWMLLSQVALLILLYIISLFDP- 103
Cdd:TIGR02718 14 GIPIGLAMDALPTLLREDGAPLTALAFLPLVGLPWVVKFLWAPLVDNWWSWRLGRRRSWVLPMQCLVSACLASLALVGPd 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 104 LTQLGTVANIALLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPGGLSLYLAAIYPWETVFLWTALCM 183
Cdd:TIGR02718 94 VAGAGWAVGLLACASLASATQDIATDGMAAEHFNGRTLAKGNAVQIAGVMIGFFGGGAGTLVLFGKFGQRPAFLLVACVP 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 184 LAGIFMTLFLAkepkiDMQQTNQPFYQAFWIPLQEFFQRKgviQAIGFLLFLFLYKFGDSFATTLQTKFIYDMGFSKEDI 263
Cdd:TIGR02718 174 LASLVCVLWLK-----DRAVASPEAPLARRASLFRFFRRP---LAWSLLALALLSAMTAVSGFGLSKLYLVDAGWPLEWI 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 264 AIVVKSTALWSSILSGLAGGMIMLKLGINRALWLfgLVQMVTIGGFIWLAAFGHFdvITSAELWKLGVVIAAEYIGVGLG 343
Cdd:TIGR02718 246 GRLGMAGGAVTVLLGCGGGAWLVRRAGLWRTFIL--GVGLAGSLALLWFAQAAFW--LAPGIAVAWSCSAFGSLITGITS 321
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1175225 344 TAAFVAFMARESNPLYTATQLALFTSLSALPSKVLGILSGYVVGAVGYYQYFWFCLFLAIPGMLCLFWV 412
Cdd:TIGR02718 322 VAIYTAFMRFAGDGDQAGTDVTAVQSTRDLGELIASSIAGYLTDRFGYAGGFLSGTVLAVLAILLAVRL 390
|
|
| MFS |
cd06174 |
Major Facilitator Superfamily; The Major Facilitator Superfamily (MFS) is a large and diverse ... |
18-410 |
4.84e-08 |
|
Major Facilitator Superfamily; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.
Pssm-ID: 349949 [Multi-domain] Cd Length: 378 Bit Score: 54.74 E-value: 4.84e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 18 AFTGFNSGLPLFVLSQMLPVWLTDKHLSIELIGAVTGV--MLPYGLKFLWAPLLDRYfpsflgRRRSWMLLSQVALLILL 95
Cdd:cd06174 2 LLGFFLTGLARGLISPLLPALLQSFGLSASQLGLLFALfsLGYALLQPLAGLLADRF------GRRPVLLLGLLLFALGA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 96 YIISLfdpLTQLGTVANIALLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPGGLSLYLAAI--YPWE 173
Cdd:cd06174 76 LLFAF---APSFWLLLLGRFLLGLGSGLIDPAVLALIADLFPERERGRALGLLQAFGSVGGILGPLLGGILASSlgFGWR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 174 TVFLWTALCMLAGIFMTLFLAKEPKIDMQQTNQPFYQA-FWIPLQEFFQRKGVIQAIGfllFLFLYKFGDSFATTLQTKF 252
Cdd:cd06174 153 AVFLIAAALALLAAILLLLVVPDPPESARAKNEEASSKsVLKLLKRVLKNPGLWLLLL---AIFLVNLAYYSFSTLLPLF 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 253 IYDMGFSKEDIAIVVKSTALWSSILSGLAGGMIMLKLGINRALWLFGLVQMVTIGGFIWLAAFGHFDVITSAELWklgvv 332
Cdd:cd06174 230 LLDLGGLSVAVAGLLLSLFGLAGALGSLLLGLLSDRLIGRKPLLLIGLLLMALGLALLLLAPSLLLLLLLLLLLG----- 304
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1175225 333 iaaeyIGVGLGTAAFVAFMARESNPLYTATQLALFTSLSALPSKVLGILSGYV-VGAVGYYQYFWFCLFLAIPGMLCLF 410
Cdd:cd06174 305 -----FGLGGLLPLSFALIAELFPPEIRGTAFGLLNTFGFLGGAIGPLLAGFLlAATFGLTGAFLVLAVLLLLAAILLL 378
|
|
| MFS_1 |
pfam07690 |
Major Facilitator Superfamily; |
18-375 |
8.04e-07 |
|
Major Facilitator Superfamily;
Pssm-ID: 429598 [Multi-domain] Cd Length: 344 Bit Score: 50.49 E-value: 8.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 18 AFTGFNSGLPLFVLSQMLPVWLT-DKHLSIELIG-AVTGVMLPYGL-KFLWAPLLDRYfpsflgRRRSWMLLSQVALLIL 94
Cdd:pfam07690 2 FLAAFLAALGRSLLGPALPLLLAeDLGISPTEIGlLLTLFSLGYALaQPLAGRLSDRF------GRRRVLLIGLLLFALG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 95 LYIISLFDPLTQLGTVAniaLLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPGGLSLYLAAIYPWET 174
Cdd:pfam07690 76 LLLLLFASSLWLLLVLR---VLQGLGAGALFPAALALIADWFPPEERGRALGLVSAGFGLGAALGPLLGGLLASLFGWRA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 175 VFLWTALCMLAGIFMTLFLAKEPKIDMQQTNQPFYQAFWIPLQEFFQRKGVIQAIGFLLFLFLYkfgdSFATTLQTKFIY 254
Cdd:pfam07690 153 AFLILAILSLLAAVLLLLPRPPPESKRPKPAEEARLSLIVAWKALLRDPVLWLLLALLLFGFAF----FGLLTYLPLYQE 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 255 DMGFSKEDIAIVVKSTALwSSILSGLAGGMIMLKLGINRALWLFGLVQMVTIGGFIWLAAFGHFDVITsaelwklgVVIA 334
Cdd:pfam07690 229 VLGLSALLAGLLLGLGGL-LGAIGRLLLGRLSDRLGRRRRLLLALLLLILAALGLLLLSLTLSSLWLL--------LALL 299
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 1175225 335 AEYIGVGLGTAAFVAFMARESNPLYTATQLALFTSLSALPS 375
Cdd:pfam07690 300 LLGFGFGLVFPALNALVSDLAPKEERGTASGLYNTAGSLGG 340
|
|
| Acatn |
pfam13000 |
Acetyl-coenzyme A transporter 1; The mouse Acatn is a 61 kDa hydrophobic protein with six to ... |
42-146 |
2.64e-05 |
|
Acetyl-coenzyme A transporter 1; The mouse Acatn is a 61 kDa hydrophobic protein with six to 10 transmembrane domains. It appears to promote 9-O-acetylation in gangliosides.
Pssm-ID: 372424 [Multi-domain] Cd Length: 543 Bit Score: 46.20 E-value: 2.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 42 KHLSIELIGAVTGVMLPYGLKFLWAPLLDRYFPSFLGRRRSWMLLSQVALLILLYII---------------SLFDPLTQ 106
Cdd:pfam13000 31 KETSFTSLGIFSMATYPYSLKILWSPIVDSIYSKKIGRRRSWIIPVQLVSGIMLIILgyciskglifpgvddAFHGRLSK 110
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1175225 107 LGTVANIALLIAFFS------ATQDIVLDAYRREILSDHELGLGNT 146
Cdd:pfam13000 111 GVLNVNITTLTWYFGilvflcATQDIAVDGWALTILSKQSLSYAST 156
|
|
| AraJ |
COG2814 |
Predicted arabinose efflux permease AraJ, MFS family [Carbohydrate transport and metabolism]; |
14-373 |
5.41e-05 |
|
Predicted arabinose efflux permease AraJ, MFS family [Carbohydrate transport and metabolism];
Pssm-ID: 442063 [Multi-domain] Cd Length: 348 Bit Score: 44.96 E-value: 5.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 14 MLICAFTGFNSGLPLFVLSQMLPVWLTDKHLSIELIGAVTGV-MLPYGL-KFLWAPLLDRYfpsflGRRRSwMLLSQVAL 91
Cdd:COG2814 12 LLALALGAFLSGLGIGIVLPALPLIAADLGASPAQAGLVVTAyLLGAALgAPLAGRLADRF-----GRRRV-LLLGLLLF 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 92 LILLYIISLFDPLTQLGTVAniaLLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPGGLSLYLAAIYP 171
Cdd:COG2814 86 ALGSLLCALAPSLWLLLAAR---FLQGLGAGALFPAALALIADLVPPERRGRALGLLGAGLGLGPALGPLLGGLLADLFG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 172 WETVFLWTALCMLAGIFMTLFLAKEPKIDMQqtnqpfyQAFWIPLQEFFQRKGVIQAIGFLLFLFLYKFGdsFATTLQTK 251
Cdd:COG2814 163 WRWVFLVNAVLALLALLLLLRLLPESRPAAR-------ARLRGSLRELLRRPRLLLLLLLAFLLGFGFFA--LFTYLPLY 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 252 FIYDMGFSKEDIAIVVKSTALwSSILSGLAGGMIMLKLGINRALWLFGLVQMVTIGGFIWLAAFghfdvitsaelWKLGV 331
Cdd:COG2814 234 LQEVLGLSASAAGLLLALFGL-GGVLGALLAGRLADRFGRRRLLLIGLLLLALGLLLLALAGSL-----------WLLLL 301
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1175225 332 VIAAEYIGVGLGTAAFVAFMARESNPLYTATQLALFTSLSAL 373
Cdd:COG2814 302 ALFLLGFGFGLLFPLLQALVAELAPPEARGRASGLYNSAFFL 343
|
|
| MFS_MefA_like |
cd06173 |
Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of ... |
35-411 |
6.18e-04 |
|
Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters; This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 340863 [Multi-domain] Cd Length: 383 Bit Score: 41.83 E-value: 6.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 35 LPVWLTDKHLSIELIGAVTGV-MLPYGLKFLWA-PLLDRYfpsflgRRRSWMLLSQV--ALLILLYIISLFDPLTQLGTV 110
Cdd:cd06173 22 LPWLVLQLTGSALLVGLVLAAfFLPFLLFSPFAgVLADRF------DRRRLLILADLlrALLAAVLALLALLGSLSLWLL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 111 ANIALLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPGGLSLYLAAIYPWETVFLWTALCMLAGIFMT 190
Cdd:cd06173 96 LVLAFLLGIASAFFGPARQALLPELVPKEQLVRANALNSLATQLARIIGPALGGLLVALLGPGGAFAINALSFLLSALLL 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 191 LFLAKEPKIDMQQTNQPFYQAFWIPLQEFFQRKGVIQAIGFLLFLFLykFGDSFATTLQTKFIYDMGFSKEDIAIVVKST 270
Cdd:cd06173 176 LFIRRPPPAAPGESSSLLLRDLREGLRYLRRSPLLRLLLLALALFAL--LGGALTVLLPLLAKEVLGGGAAGYGLLLAAF 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 271 AlwssiLSGLAGGMIMLKLGINRALWLFGLVQMVTIGGFIWLAAFghfdvitSAELWKLGVVIAAEYIGVGLGTAAFVAF 350
Cdd:cd06173 254 G-----VGALLGALLLGRLSKRRRRGRLLLIGALLLGLALLVLGL-------SPSLWLLLAALFLLGLAGGLFNVPLNTL 321
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1175225 351 MARESNPLYTATQLALFTSLSALPSKVLGILSGYVVGAVGYYQYFWFCLFLAIPGMLCLFW 411
Cdd:cd06173 322 LQLRVPDELRGRVFSVYNALNSGAMPLGALLAGLLADALGLSAVFLLAGALLLLAALLLLL 382
|
|
| UhpC |
COG2271 |
Sugar phosphate permease [Carbohydrate transport and metabolism]; |
14-414 |
9.95e-04 |
|
Sugar phosphate permease [Carbohydrate transport and metabolism];
Pssm-ID: 441872 [Multi-domain] Cd Length: 363 Bit Score: 41.01 E-value: 9.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 14 MLICAFTGFNSGLPLFVLSQMLPVWLTDKHLSIELIGAVTGV-MLPYGL-KFLWAPLLDRYfpsflGRRRsWMLLSQVAL 91
Cdd:COG2271 12 LALLFLAYFLNYLDRSNLSVAAPPLQADLGLSAAQLGLLASAfFLGYALgQIPAGLLADRF-----GRRR-VLAIGLLLW 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 92 LILLYIISLFDPLTQLGTvanIALLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPGGLSLYLAAIYP 171
Cdd:COG2271 86 GLATLLFGFATSFWQLLL---LRFLLGLGEAGFFPAALKLIAEWFPPKERGRALGIFNAGGPLGGALAPPLLGWLLAAFG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 172 WETVFLWTAL-CMLAGIFMTLFLAkepkidmqqtnqpfyqafwiplqeffqrkgviqAIGFLLFLFLYKFGDSFATTLQT 250
Cdd:COG2271 163 WRAAFLILGLpGLLLALLRFWLLA---------------------------------LAYFLVYFALYGFLTWLPTYLVE 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 251 KFiydmGFSKEDIAIVVkSTALWSSILSGLAGGMIMLKLGINRALWLFGLvqMVTIGGFIWLAAFGHfdvitsaELWKLG 330
Cdd:COG2271 210 VR----GLSLAQAGLLL-SLPFLAGIVGSLLGGWLSDRLGRRRKLVLAIG--LLLAALALLLLALLP-------SPALAI 275
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 331 VVIAAEYIGVGLGTAAFVAFMARESNPLYTATQLALFTSLSALPSKVLGILSGYVVGAVGYYQYFWFCLFLAIPGMLCLF 410
Cdd:COG2271 276 ALLFLAGFGLGGAFGLLWALAAELFPKKARGTASGLVNTFGFLGGALGPLLVGYLLDATGYQAAFLLLAALALLAALLAL 355
|
....
gi 1175225 411 WVAP 414
Cdd:COG2271 356 LLLR 359
|
|
| NarK |
COG2223 |
Nitrate/nitrite transporter NarK [Inorganic ion transport and metabolism]; |
139-412 |
1.65e-03 |
|
Nitrate/nitrite transporter NarK [Inorganic ion transport and metabolism];
Pssm-ID: 441825 [Multi-domain] Cd Length: 392 Bit Score: 40.25 E-value: 1.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 139 HELGLGNTIHINAYRIAGLIPGGLSLYLAAIYPWETVFLWTALCMLAGIFMTLFLAKEPKIDMQQTNQpfyQAFWIPLQE 218
Cdd:COG2223 125 DRRGLALGLAAGGGNLGAAVAAFLAPLLIAAFGWRNAFLILGILLLVVAVLAWLFLRDPPAGAAAAAK---ASLRDQLEA 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 219 FFQRKGVIQAIGFLLFLFLYKFGDSFATTLqtkFIYDMGFSKEDIAIVVkSTALWSSILSGLAGGMIMLKLGINRALWLF 298
Cdd:COG2223 202 LRDPRFWLLSLLYFGTFGSFIGFSSWLPPY---LVDQFGLSAATAGLLA-ALFALLGALGRPLGGWLSDRIGGRRVLLIV 277
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 299 GLVQMVTIGGFIWlaafghfdviTSAELWKLGVVIAAEYIGVGLGTAAFVAFMARESNPLYTATQLALFTSLSALPSKVL 378
Cdd:COG2223 278 FALMALGLLLLAL----------ALGSLWLFLVLFLLLGLALGGGNGAVFALVPDIFPTKNAGAVYGLVGAAGGLGGFLG 347
|
250 260 270
....*....|....*....|....*....|....*
gi 1175225 379 GILSGYVVGAVGYYQY-FWFCLFLAIPGMLCLFWV 412
Cdd:COG2223 348 PLLFGALLDATGSYTAaFLVFAVLALVALVLTLLL 382
|
|
| MFS_MdtG_SLC18_like |
cd17325 |
bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator ... |
17-411 |
2.00e-03 |
|
bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters; This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 340883 [Multi-domain] Cd Length: 375 Bit Score: 40.25 E-value: 2.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 17 CAFTGFNSGLPLFVLSQMLPVWLTDKHLSIELIGAVTGVmlpYGL-----KFLWAPLLDRYfpsflGRRRSwMLLSQVAL 91
Cdd:cd17325 1 LSLALFLDMLGYGIIIPILPLYAESLGASVAQIGLIVAA---YALaqllfSPPAGRLSDRF-----GRKRL-LLLGLLLL 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 92 LILLYIISLFDPLTQLGTVAniaLLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPGGLSLYLAAIYP 171
Cdd:cd17325 72 AVSTLLFAFATSYWQLLLAR---FLQGLASAAVWPAAMALIADIAPPEERGRAMGIFSSAIGLGFLIGPLLGGLLADALG 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 172 WETVFLWTALCMLAGIFMTLFLAKEPKidMQQTNQPFYQAFWIPLQEFFQRKGVIQAIGFLLFLFLYKFGdSFATTLQTK 251
Cdd:cd17325 149 YRAPFLVCAALALLALVLALLLLPEPR--PPPNKRAVSAARLRSGLRLLLRDRRLLALFLAIFVLAFAFG-ALEPFLPLY 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 252 FIYDMGFSKEDIAIVVKSTALWSSILSGLAGGMIMlklginralwLFGLVQMVTIGGFIWLAAFghFDVITSAELWKLGV 331
Cdd:cd17325 226 AAELGGLSPAQIGLLFGAQGLASALSQPPAGKLSD----------RIGRKPLILIGLLLSAVAL--LLLPLATSFWLLLL 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175225 332 VIAAEYIGVGLGTAAFVAFMARESNPLYTATQLALFTSLSALPSKVLGILSGYVVGAVGYYQYFWFCLFLAIPGMLCLFW 411
Cdd:cd17325 294 LLALLGLGLGLVFPATLALLADIVPPEGRGTAMGLFNTAFSLGMVLGPLLGGFLYDAFGFATPFLAAAALLLLAAVLFLL 373
|
|
| |
