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Conserved domains on  [gi|135834|sp|P06454|]
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RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha-1

Protein Classification

prothymosin alpha( domain architecture ID 10505379)

prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Prothymosin pfam03247
Prothymosin/parathymosin family; Prothymosin alpha and parathymosin are two ubiquitous small ...
 2-110 8.31e-13

Prothymosin/parathymosin family; Prothymosin alpha and parathymosin are two ubiquitous small acidic nuclear proteins that are thought to be involved in cell cycle progression, proliferation, and cell differentiation.


:

Pssm-ID: 460859 [Multi-domain]  Cd Length: 109  Bit Score: 59.53  E-value: 8.31e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 135834       2 SDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPANGNAENEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDE 81
Cdd:pfam03247   1 SDTAVDTASELSTKDLKEKKEVVEEAEKGKDAPANGNAENEENGAQEAEEEVEFEEEEDEEEEEEEEEEGEEEDGEEEEE 80

                          90       100
                  ....*....|....*....|....*....
gi 135834      82 EAESATGKRAAEDDEDDDVDTKKQKTDED 110
Cdd:pfam03247  81 EAEGAAVKRAAEDEEDDDVETKKQKTEEG 109
 
Name Accession Description Interval E-value
Prothymosin pfam03247
Prothymosin/parathymosin family; Prothymosin alpha and parathymosin are two ubiquitous small ...
 2-110 8.31e-13

Prothymosin/parathymosin family; Prothymosin alpha and parathymosin are two ubiquitous small acidic nuclear proteins that are thought to be involved in cell cycle progression, proliferation, and cell differentiation.


Pssm-ID: 460859 [Multi-domain]  Cd Length: 109  Bit Score: 59.53  E-value: 8.31e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 135834       2 SDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPANGNAENEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDE 81
Cdd:pfam03247   1 SDTAVDTASELSTKDLKEKKEVVEEAEKGKDAPANGNAENEENGAQEAEEEVEFEEEEDEEEEEEEEEEGEEEDGEEEEE 80

                          90       100
                  ....*....|....*....|....*....
gi 135834      82 EAESATGKRAAEDDEDDDVDTKKQKTDED 110
Cdd:pfam03247  81 EAEGAAVKRAAEDEEDDDVETKKQKTEEG 109
 
Name Accession Description Interval E-value
Prothymosin pfam03247
Prothymosin/parathymosin family; Prothymosin alpha and parathymosin are two ubiquitous small ...
 2-110 8.31e-13

Prothymosin/parathymosin family; Prothymosin alpha and parathymosin are two ubiquitous small acidic nuclear proteins that are thought to be involved in cell cycle progression, proliferation, and cell differentiation.


Pssm-ID: 460859 [Multi-domain]  Cd Length: 109  Bit Score: 59.53  E-value: 8.31e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 135834       2 SDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPANGNAENEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDE 81
Cdd:pfam03247   1 SDTAVDTASELSTKDLKEKKEVVEEAEKGKDAPANGNAENEENGAQEAEEEVEFEEEEDEEEEEEEEEEGEEEDGEEEEE 80

                          90       100
                  ....*....|....*....|....*....
gi 135834      82 EAESATGKRAAEDDEDDDVDTKKQKTDED 110
Cdd:pfam03247  81 EAEGAAVKRAAEDEEDDDVETKKQKTEEG 109
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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