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Conserved domains on  [gi|1232213786|gb|OYV12812|]
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MAG: transitional endoplasmic reticulum ATPase [Methanosaeta sp. NSM2]

Protein Classification

CDC48_N domain-containing protein( domain architecture ID 10492274)

CDC48_N domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CDC48_N pfam02359
Cell division protein 48 (CDC48), N-terminal domain; This domain has a double psi-beta barrel ...
 6-89 2.42e-37

Cell division protein 48 (CDC48), N-terminal domain; This domain has a double psi-beta barrel fold and includes VCP-like ATPase and N-ethylmaleimide sensitive fusion protein N-terminal domains. Both the VAT and NSF N-terminal functional domains consist of two structural domains of which this is at the N-terminus. The VAT-N domain found in AAA ATPases pfam00004 is a substrate 185-residue recognition domain.


:

Pssm-ID: 426738  Cd Length: 85  Bit Score: 121.15  E-value: 2.42e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232213786   6 LKVAKAYPNDSARGIARLDPNALLTLRLSPGDIIEIEGKRMTAAKVWRADRQDWSQDYIRIDGFIRQNAGVGIGDRVKIR 85
Cdd:pfam02359   2 LRVAEAPDRDVGRGIARLNPEDMEELGLFPGDVVEIKGKRKTVAIVWSAYPEDEGPGIIRMDGVTRKNAGVSIGDTVTVR 81


                  ....
gi 1232213786  86 KARF 89
Cdd:pfam02359  82 PAEV 85
 
Name Accession Description Interval E-value
CDC48_N pfam02359
Cell division protein 48 (CDC48), N-terminal domain; This domain has a double psi-beta barrel ...
 6-89 2.42e-37

Cell division protein 48 (CDC48), N-terminal domain; This domain has a double psi-beta barrel fold and includes VCP-like ATPase and N-ethylmaleimide sensitive fusion protein N-terminal domains. Both the VAT and NSF N-terminal functional domains consist of two structural domains of which this is at the N-terminus. The VAT-N domain found in AAA ATPases pfam00004 is a substrate 185-residue recognition domain.


Pssm-ID: 426738  Cd Length: 85  Bit Score: 121.15  E-value: 2.42e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232213786   6 LKVAKAYPNDSARGIARLDPNALLTLRLSPGDIIEIEGKRMTAAKVWRADRQDWSQDYIRIDGFIRQNAGVGIGDRVKIR 85
Cdd:pfam02359   2 LRVAEAPDRDVGRGIARLNPEDMEELGLFPGDVVEIKGKRKTVAIVWSAYPEDEGPGIIRMDGVTRKNAGVSIGDTVTVR 81


                  ....
gi 1232213786  86 KARF 89
Cdd:pfam02359  82 PAEV 85
CDC48_N smart01073
Cell division protein 48 (CDC48) N-terminal domain; This domain has a double psi-beta barrel ...
 6-87 1.09e-31

Cell division protein 48 (CDC48) N-terminal domain; This domain has a double psi-beta barrel fold and includes VCP-like ATPase and N-ethylmaleimide sensitive fusion protein N-terminal domains. Both the VAT and NSF N-terminal functional domains consist of two structural domains of which this is at the N-terminus. The VAT-N domain found in AAA ATPases is a substrate 185-residue recognition domain.


Pssm-ID: 215012 [Multi-domain]  Cd Length: 82  Bit Score: 106.54  E-value: 1.09e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232213786    6 LKVAKA-YPNDSARGIARLDPNALLTLRLSPGDIIEIEGKRMTAAKVWRADRQDWsQDYIRIDGFIRQNAGVGIGDRVKI 84
Cdd:smart01073   1 LRVAEApSDEDVGRGIARLSPEDMDELGLFPGDYVLITGKRRTVAIVWPAYPEDP-GGIIRIDGVQRKNAGVSIGDTVTV 79


                   ...
gi 1232213786   85 RKA 87
Cdd:smart01073  80 RKA 82
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
 4-99 3.23e-29

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 109.61  E-value: 3.23e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232213786   4 IHLKVAKAYPNDSARGIARLDPNALLTLRLSPGDIIEIE-GKRMTAAKVWRADRQDWSQDYIRIDGFIRQNAGVGIGDRV 82
Cdd:TIGR01243   2 VELRVAEAYPRDVGRGIVRIDRQTAARLGVEPGDFVEIEkGDRSVVAIVWPLRPDDEGRGIIRMDGYLRANAGVTIGDTV 81

                          90
                  ....*....|....*..
gi 1232213786  83 KIRKARFADAQKIILAP 99
Cdd:TIGR01243  82 TVERAEVKEAKKVVLAP 98
 
Name Accession Description Interval E-value
CDC48_N pfam02359
Cell division protein 48 (CDC48), N-terminal domain; This domain has a double psi-beta barrel ...
 6-89 2.42e-37

Cell division protein 48 (CDC48), N-terminal domain; This domain has a double psi-beta barrel fold and includes VCP-like ATPase and N-ethylmaleimide sensitive fusion protein N-terminal domains. Both the VAT and NSF N-terminal functional domains consist of two structural domains of which this is at the N-terminus. The VAT-N domain found in AAA ATPases pfam00004 is a substrate 185-residue recognition domain.


Pssm-ID: 426738  Cd Length: 85  Bit Score: 121.15  E-value: 2.42e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232213786   6 LKVAKAYPNDSARGIARLDPNALLTLRLSPGDIIEIEGKRMTAAKVWRADRQDWSQDYIRIDGFIRQNAGVGIGDRVKIR 85
Cdd:pfam02359   2 LRVAEAPDRDVGRGIARLNPEDMEELGLFPGDVVEIKGKRKTVAIVWSAYPEDEGPGIIRMDGVTRKNAGVSIGDTVTVR 81


                  ....
gi 1232213786  86 KARF 89
Cdd:pfam02359  82 PAEV 85
CDC48_N smart01073
Cell division protein 48 (CDC48) N-terminal domain; This domain has a double psi-beta barrel ...
 6-87 1.09e-31

Cell division protein 48 (CDC48) N-terminal domain; This domain has a double psi-beta barrel fold and includes VCP-like ATPase and N-ethylmaleimide sensitive fusion protein N-terminal domains. Both the VAT and NSF N-terminal functional domains consist of two structural domains of which this is at the N-terminus. The VAT-N domain found in AAA ATPases is a substrate 185-residue recognition domain.


Pssm-ID: 215012 [Multi-domain]  Cd Length: 82  Bit Score: 106.54  E-value: 1.09e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232213786    6 LKVAKA-YPNDSARGIARLDPNALLTLRLSPGDIIEIEGKRMTAAKVWRADRQDWsQDYIRIDGFIRQNAGVGIGDRVKI 84
Cdd:smart01073   1 LRVAEApSDEDVGRGIARLSPEDMDELGLFPGDYVLITGKRRTVAIVWPAYPEDP-GGIIRIDGVQRKNAGVSIGDTVTV 79


                   ...
gi 1232213786   85 RKA 87
Cdd:smart01073  80 RKA 82
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
 4-99 3.23e-29

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 109.61  E-value: 3.23e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232213786   4 IHLKVAKAYPNDSARGIARLDPNALLTLRLSPGDIIEIE-GKRMTAAKVWRADRQDWSQDYIRIDGFIRQNAGVGIGDRV 82
Cdd:TIGR01243   2 VELRVAEAYPRDVGRGIVRIDRQTAARLGVEPGDFVEIEkGDRSVVAIVWPLRPDDEGRGIIRMDGYLRANAGVTIGDTV 81

                          90
                  ....*....|....*..
gi 1232213786  83 KIRKARFADAQKIILAP 99
Cdd:TIGR01243  82 TVERAEVKEAKKVVLAP 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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