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Conserved domains on  [gi|1230355647|gb|OYJ31760|]
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6-phosphogluconolactonase [Escherichia coli]

Protein Classification

6-phosphogluconolactonase( domain architecture ID 11485154)

6-phosphogluconolactonase catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate, which is the the second step of the oxidative phase of the pentose phosphate pathway

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK11028 PRK11028
6-phosphogluconolactonase; Provisional
 2-331 0e+00

6-phosphogluconolactonase; Provisional


:

Pssm-ID: 182912 [Multi-domain]  Cd Length: 330  Bit Score: 667.82  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647   2 KQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIApDDGALTFAAESALP 81
Cdd:PRK11028    1 KQIVYIASPESQQIHVWNLNHEGALTLLQVVDVPGQVQPMVISPDKRHLYVGVRPEFRVLSYRIA-DDGALTFAAESPLP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647  82 GSPTHISTDHQGQFVFVGSYNAGNVSVTRL-EDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDG 160
Cdd:PRK11028   80 GSPTHISTDHQGRFLFSASYNANCVSVSPLdKDGIPVAPIQIIEGLEGCHSANIDPDNRTLWVPCLKEDRIRLFTLSDDG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647 161 HLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDG 240
Cdd:PRK11028  160 HLVAQEPAEVTTVEGAGPRHMVFHPNQQYAYCVNELNSSVDVWQLKDPHGEIECVQTLDMMPADFSDTRWAADIHITPDG 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647 241 RHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVG 320
Cdd:PRK11028  240 RHLYACDRTASLISVFSVSEDGSVLSFEGHQPTETQPRGFNIDHSGKYLIAAGQKSHHISVYEIDGETGLLTELGRYAVG 319

                         330
                  ....*....|.
gi 1230355647 321 QGPMWVVVNAH 331
Cdd:PRK11028  320 QGPMWVSVLAL 330
 
Name Accession Description Interval E-value
PRK11028 PRK11028
6-phosphogluconolactonase; Provisional
 2-331 0e+00

6-phosphogluconolactonase; Provisional


Pssm-ID: 182912 [Multi-domain]  Cd Length: 330  Bit Score: 667.82  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647   2 KQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIApDDGALTFAAESALP 81
Cdd:PRK11028    1 KQIVYIASPESQQIHVWNLNHEGALTLLQVVDVPGQVQPMVISPDKRHLYVGVRPEFRVLSYRIA-DDGALTFAAESPLP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647  82 GSPTHISTDHQGQFVFVGSYNAGNVSVTRL-EDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDG 160
Cdd:PRK11028   80 GSPTHISTDHQGRFLFSASYNANCVSVSPLdKDGIPVAPIQIIEGLEGCHSANIDPDNRTLWVPCLKEDRIRLFTLSDDG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647 161 HLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDG 240
Cdd:PRK11028  160 HLVAQEPAEVTTVEGAGPRHMVFHPNQQYAYCVNELNSSVDVWQLKDPHGEIECVQTLDMMPADFSDTRWAADIHITPDG 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647 241 RHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVG 320
Cdd:PRK11028  240 RHLYACDRTASLISVFSVSEDGSVLSFEGHQPTETQPRGFNIDHSGKYLIAAGQKSHHISVYEIDGETGLLTELGRYAVG 319

                         330
                  ....*....|.
gi 1230355647 321 QGPMWVVVNAH 331
Cdd:PRK11028  320 QGPMWVSVLAL 330
Pgl COG2706
6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];
2-328 8.76e-126

6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];


Pssm-ID: 442025 [Multi-domain]  Cd Length: 352  Bit Score: 364.23  E-value: 8.76e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647   2 KQTVYIAS---PESQQIHVWNLNHE-GALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRP-EFRVLAYRIAPDDGALTFAA 76
Cdd:COG2706     7 STFVYVGTytsGESEGIYVFRLDTAtGELTLLGLVAALGNPSFLALSPDGRFLYAVNEVdDGGVSAFRIDPADGTLTLLN 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647  77 ESALPG-SPTHISTDHQGQFVFVGSYNAGNVSVTRL-EDGLPVGVVDVVE-----------GLDGCHSANISPDNRTLWV 143
Cdd:COG2706    87 TVSSGGaSPCHLSVDPDGRFLFVANYGGGSVSVFPIdADGSLGEPVQVIQhegsgpnperqEGPHAHSVVFDPDGRFLYV 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647 144 PALKQDRICLFTVS-DDGHLvaQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMP 222
Cdd:COG2706   167 PDLGTDRIYVYRLDpATGKL--PEPPEVSLPPGSGPRHLAFHPNGRFAYVINELDSTVSVYAYDAATGTLTLIQTVSTLP 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647 223 ENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTE-TQPRGFNVDHSGKYLIAAGQKSHHISV 301
Cdd:COG2706   245 EDFTGENWAADIHISPDGRFLYVSNRGHNSIAVFAIDADGGKLTLVGHVPTGgKWPRDFAIDPDGRFLLVANQKSDNITV 324

                         330       340
                  ....*....|....*....|....*..
gi 1230355647 302 YEIVGEQGLLHEKGRYAVGQGPMWVVV 328
Cdd:COG2706   325 FRIDADTGKLTPTGRSVPVPSPVCVAF 351
Lactonase pfam10282
Lactonase, 7-bladed beta-propeller; This entry contains bacterial 6-phosphogluconolactonases ...
 4-324 5.14e-121

Lactonase, 7-bladed beta-propeller; This entry contains bacterial 6-phosphogluconolactonases (6PGL)YbhE-type (EC:3.1.1.31) which hydrolyse 6-phosphogluconolactone to 6-phosphogluconate. The entry also contains the fungal muconate lactonising enzyme carboxy-cis,cis-muconate cyclase (EC:5.5.1.5) and muconate cycloisomerase (EC:5.5.1.1), which convert cis,cis-muconates to muconolactones and vice versa as part of the microbial beta-ketoadipate pathway. Structures of proteins in this family have revealed a 7-bladed beta-propeller fold.


Pssm-ID: 431196 [Multi-domain]  Cd Length: 340  Bit Score: 351.52  E-value: 5.14e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647   4 TVYIAS---PESQQIHVWNLNHE-GALTLTQVVDVPGQVQPMVVSPDKRYLYVGVR--PEFRVLAYRIAPDDGALTFAAE 77
Cdd:pfam10282   1 TLYVGTytkGDSKGIYVLTLDTEtGALTLLGLVAEVGNPSYLALSPDGRTLYAVNEegDQGGVAAFRIDPDSGALTLLNQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647  78 -SALPGSPTHISTDHQGQFVFVGSYNAGNVSVTRL-EDGLPVGVVDVV--EGLDG---------CHSANISPDNRTLWVP 144
Cdd:pfam10282  81 vPTGGASPCHLSVDPDGRFLFVANYHGGSVSVFPLdADGSLGELSQVVqhEGSGPpperqesphPHSVDLTPDGKFLVVP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647 145 ALKQDRICLFTVSDD-GHLVAqdPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPE 223
Cdd:pfam10282 161 DLGTDRVRVYKLDAGgGKLTP--PASVQTPPGSGPRHLAFHPNGKYAYVVNELSSTVTVFEYDPATGTFEELQTVSTLPE 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647 224 NFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQ-PRGFNVDHSGKYLIAAGQKSHHISVY 302
Cdd:pfam10282 239 GFTGTNGAAAIRVSPDGKFLYVSNRGHDSIAVFAVDEAGGTLTLVERVSTEGDfPRDFNIDPDGKFLVVANQDSDNVTVF 318

                         330       340
                  ....*....|....*....|..
gi 1230355647 303 EIVGEQGLLHEKGRYAVGQGPM 324
Cdd:pfam10282 319 RRDPETGKLTLLGKDIEVPEPV 340
 
Name Accession Description Interval E-value
PRK11028 PRK11028
6-phosphogluconolactonase; Provisional
 2-331 0e+00

6-phosphogluconolactonase; Provisional


Pssm-ID: 182912 [Multi-domain]  Cd Length: 330  Bit Score: 667.82  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647   2 KQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIApDDGALTFAAESALP 81
Cdd:PRK11028    1 KQIVYIASPESQQIHVWNLNHEGALTLLQVVDVPGQVQPMVISPDKRHLYVGVRPEFRVLSYRIA-DDGALTFAAESPLP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647  82 GSPTHISTDHQGQFVFVGSYNAGNVSVTRL-EDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDG 160
Cdd:PRK11028   80 GSPTHISTDHQGRFLFSASYNANCVSVSPLdKDGIPVAPIQIIEGLEGCHSANIDPDNRTLWVPCLKEDRIRLFTLSDDG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647 161 HLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDG 240
Cdd:PRK11028  160 HLVAQEPAEVTTVEGAGPRHMVFHPNQQYAYCVNELNSSVDVWQLKDPHGEIECVQTLDMMPADFSDTRWAADIHITPDG 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647 241 RHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVG 320
Cdd:PRK11028  240 RHLYACDRTASLISVFSVSEDGSVLSFEGHQPTETQPRGFNIDHSGKYLIAAGQKSHHISVYEIDGETGLLTELGRYAVG 319

                         330
                  ....*....|.
gi 1230355647 321 QGPMWVVVNAH 331
Cdd:PRK11028  320 QGPMWVSVLAL 330
Pgl COG2706
6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];
2-328 8.76e-126

6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];


Pssm-ID: 442025 [Multi-domain]  Cd Length: 352  Bit Score: 364.23  E-value: 8.76e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647   2 KQTVYIAS---PESQQIHVWNLNHE-GALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRP-EFRVLAYRIAPDDGALTFAA 76
Cdd:COG2706     7 STFVYVGTytsGESEGIYVFRLDTAtGELTLLGLVAALGNPSFLALSPDGRFLYAVNEVdDGGVSAFRIDPADGTLTLLN 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647  77 ESALPG-SPTHISTDHQGQFVFVGSYNAGNVSVTRL-EDGLPVGVVDVVE-----------GLDGCHSANISPDNRTLWV 143
Cdd:COG2706    87 TVSSGGaSPCHLSVDPDGRFLFVANYGGGSVSVFPIdADGSLGEPVQVIQhegsgpnperqEGPHAHSVVFDPDGRFLYV 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647 144 PALKQDRICLFTVS-DDGHLvaQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMP 222
Cdd:COG2706   167 PDLGTDRIYVYRLDpATGKL--PEPPEVSLPPGSGPRHLAFHPNGRFAYVINELDSTVSVYAYDAATGTLTLIQTVSTLP 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647 223 ENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTE-TQPRGFNVDHSGKYLIAAGQKSHHISV 301
Cdd:COG2706   245 EDFTGENWAADIHISPDGRFLYVSNRGHNSIAVFAIDADGGKLTLVGHVPTGgKWPRDFAIDPDGRFLLVANQKSDNITV 324

                         330       340
                  ....*....|....*....|....*..
gi 1230355647 302 YEIVGEQGLLHEKGRYAVGQGPMWVVV 328
Cdd:COG2706   325 FRIDADTGKLTPTGRSVPVPSPVCVAF 351
Lactonase pfam10282
Lactonase, 7-bladed beta-propeller; This entry contains bacterial 6-phosphogluconolactonases ...
 4-324 5.14e-121

Lactonase, 7-bladed beta-propeller; This entry contains bacterial 6-phosphogluconolactonases (6PGL)YbhE-type (EC:3.1.1.31) which hydrolyse 6-phosphogluconolactone to 6-phosphogluconate. The entry also contains the fungal muconate lactonising enzyme carboxy-cis,cis-muconate cyclase (EC:5.5.1.5) and muconate cycloisomerase (EC:5.5.1.1), which convert cis,cis-muconates to muconolactones and vice versa as part of the microbial beta-ketoadipate pathway. Structures of proteins in this family have revealed a 7-bladed beta-propeller fold.


Pssm-ID: 431196 [Multi-domain]  Cd Length: 340  Bit Score: 351.52  E-value: 5.14e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647   4 TVYIAS---PESQQIHVWNLNHE-GALTLTQVVDVPGQVQPMVVSPDKRYLYVGVR--PEFRVLAYRIAPDDGALTFAAE 77
Cdd:pfam10282   1 TLYVGTytkGDSKGIYVLTLDTEtGALTLLGLVAEVGNPSYLALSPDGRTLYAVNEegDQGGVAAFRIDPDSGALTLLNQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647  78 -SALPGSPTHISTDHQGQFVFVGSYNAGNVSVTRL-EDGLPVGVVDVV--EGLDG---------CHSANISPDNRTLWVP 144
Cdd:pfam10282  81 vPTGGASPCHLSVDPDGRFLFVANYHGGSVSVFPLdADGSLGELSQVVqhEGSGPpperqesphPHSVDLTPDGKFLVVP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647 145 ALKQDRICLFTVSDD-GHLVAqdPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPE 223
Cdd:pfam10282 161 DLGTDRVRVYKLDAGgGKLTP--PASVQTPPGSGPRHLAFHPNGKYAYVVNELSSTVTVFEYDPATGTFEELQTVSTLPE 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647 224 NFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQ-PRGFNVDHSGKYLIAAGQKSHHISVY 302
Cdd:pfam10282 239 GFTGTNGAAAIRVSPDGKFLYVSNRGHDSIAVFAVDEAGGTLTLVERVSTEGDfPRDFNIDPDGKFLVVANQDSDNVTVF 318

                         330       340
                  ....*....|....*....|..
gi 1230355647 303 EIVGEQGLLHEKGRYAVGQGPM 324
Cdd:pfam10282 319 RRDPETGKLTLLGKDIEVPEPV 340
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
24-250 5.07e-10

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 58.94  E-value: 5.07e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647  24 GALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYNA 103
Cdd:COG3391    10 AVLLAVLALAALAVAVAALGLGGGGPLLAAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLYVANSGS 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647 104 GNVSVTRLEDGLPVGVVDVVeglDGCHSANISPDNRTLWVPALKQDRICLFTVSDDghlvaqdpAEVTTVE-GAGPRHMV 182
Cdd:COG3391    90 GRVSVIDLATGKVVATIPVG---GGPRGLAVDPDGGRLYVADSGNGRVSVIDTATG--------KVVATIPvGAGPHGIA 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1230355647 183 FHPNEQYAYCVNELNSSVDVWelkdphgniecVQTLDMMPENFSDT----RWAADIHITPDGRHLYACDRTA 250
Cdd:COG3391   159 VDPDGKRLYVANSGSNTVSVI-----------VSVIDTATGKVVATipvgGGPVGVAVSPDGRRLYVANRGS 219
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
45-201 9.14e-09

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 55.09  E-value: 9.14e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647  45 PDKRYLYVGVRPEFRVlaYRIAPDDGALTfaAESALPGSPTHISTDHQGQFVFVGSYNAGNVSVTRLEDGLPVGVVDVve 124
Cdd:COG3391    77 ADGRRLYVANSGSGRV--SVIDLATGKVV--ATIPVGGGPRGLAVDPDGGRLYVADSGNGRVSVIDTATGKVVATIPV-- 150

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1230355647 125 gLDGCHSANISPDNRTLWVPALKQDRI-CLFTVSDdghlvAQDPAEVTTVE-GAGPRHMVFHPNEQYAYCVNELNSSVD 201
Cdd:COG3391   151 -GAGPHGIAVDPDGKRLYVANSGSNTVsVIVSVID-----TATGKVVATIPvGGGPVGVAVSPDGRRLYVANRGSNTSN 223
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
66-298 5.69e-08

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 52.77  E-value: 5.69e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647  66 APDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYNAGNVSVTRLEDGLPVGVVDVVEGLDG-CHSANISPDNRTLWVP 144
Cdd:COG3391     6 SLLVAVLLAVLALAALAVAVAALGLGGGGPLLAAASGGVVGAAVGGGGVALLAGLGLGAAAVAdADGADAGADGRRLYVA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647 145 ALKQDRICLFTVsDDGHLVAqdpaevTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDphGNIECVQTLDMMPEn 224
Cdd:COG3391    86 NSGSGRVSVIDL-ATGKVVA------TIPVGGGPRGLAVDPDGGRLYVADSGNGRVSVIDTAT--GKVVATIPVGAGPH- 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1230355647 225 fsdtrwaaDIHITPDGRHLYACDRTASLITVFsVSE-DGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHH 298
Cdd:COG3391   156 --------GIAVDPDGKRLYVANSGSNTVSVI-VSViDTATGKVVATIPVGGGPVGVAVSPDGRRLYVANRGSNT 221
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 4-145 1.43e-06

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 48.73  E-value: 1.43e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647   4 TVYIASPESQQIH--VWNLNHEGalTLTQVVDvpGQVQP--MVVSPDKRYLYVGVRPEFRVLAYRIApDDGALT----FA 75
Cdd:COG3386   105 RLYFTDMGEYLPTgaLYRVDPDG--SLRVLAD--GLTFPngIAFSPDGRTLYVADTGAGRIYRFDLD-ADGTLGnrrvFA 179

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1230355647  76 AESALPGSPTHISTDHQGqFVFVGSYNAGnvSVTRL-EDGLPVGVVDvvegLDGCHSANIS---PDNRTLWVPA 145
Cdd:COG3386   180 DLPDGPGGPDGLAVDADG-NLWVALWGGG--GVVRFdPDGELLGRIE----LPERRPTNVAfggPDLRTLYVTT 246
WD40 COG2319
WD40 repeat [General function prediction only];
14-293 8.67e-06

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 47.21  E-value: 8.67e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647  14 QIHVWNLnhEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEfRVLAYRIApdDGAL--TFAAESalpGSPTHISTDH 91
Cdd:COG2319   101 TVRLWDL--ATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADG-TVRLWDLA--TGKLlrTLTGHS---GAVTSVAFSP 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647  92 QGQFVFVGSYNaGNVSVTRLEDGLPVGVVDVVEglDGCHSANISPDNRTLwvpalkqdriclFTVSDDGHLV---AQDPA 168
Cdd:COG2319   173 DGKLLASGSDD-GTVRLWDLATGKLLRTLTGHT--GAVRSVAFSPDGKLL------------ASGSADGTVRlwdLATGK 237

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647 169 EVTTVEG--AGPRHMVFHPNEQYAYCVNElNSSVDVWELKDPhgniECVQTLDmmpenfSDTRWAADIHITPDGRHLYAC 246
Cdd:COG2319   238 LLRTLTGhsGSVRSVAFSPDGRLLASGSA-DGTVRLWDLATG----ELLRTLT------GHSGGVNSVAFSPDGKLLASG 306

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1230355647 247 --DRTASLITVfsvsEDGSVLSkeGFQPTETQPRGFNVDHSGKYLIAAG 293
Cdd:COG2319   307 sdDGTVRLWDL----ATGKLLR--TLTGHTGAVRSVAFSPDGKTLASGS 349
WD40 COG2319
WD40 repeat [General function prediction only];
3-264 3.73e-05

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 44.90  E-value: 3.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647   3 QTVYIASpESQQIHVWNLnHEGALTLTqVVDVPGQVQPMVVSPDKRYLYVGVRPEfRVLAYRIAPDDGALTFAAESALPG 82
Cdd:COG2319   175 KLLASGS-DDGTVRLWDL-ATGKLLRT-LTGHTGAVRSVAFSPDGKLLASGSADG-TVRLWDLATGKLLRTLTGHSGSVR 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647  83 SPThISTDhqGQFVFVGSYNaGNVSVTRLEDGLPVGVVDvvEGLDGCHSANISPDNRTLwvpalkqdriclFTVSDDGHL 162
Cdd:COG2319   251 SVA-FSPD--GRLLASGSAD-GTVRLWDLATGELLRTLT--GHSGGVNSVAFSPDGKLL------------ASGSDDGTV 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647 163 V---AQDPAEVTTVEG--AGPRHMVFHPNEQYAYCVNElNSSVDVWELKDPhgniECVQTLDmmpenfSDTRWAADIHIT 237
Cdd:COG2319   313 RlwdLATGKLLRTLTGhtGAVRSVAFSPDGKTLASGSD-DGTVRLWDLATG----ELLRTLT------GHTGAVTSVAFS 381

                         250       260
                  ....*....|....*....|....*..
gi 1230355647 238 PDGRHLyacdrtaslitvFSVSEDGSV 264
Cdd:COG2319   382 PDGRTL------------ASGSADGTV 396
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 3-178 5.51e-05

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 44.11  E-value: 5.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647   3 QTVYIASPESQQIHVWnlnHEGALTLTQVVDVPGQVQPMVVSPDKRyLYVgVRPEFRVlaYRIAPDDGALT-FAAESALP 81
Cdd:COG3386    19 GRLYWVDIPGGRIHRY---DPDGGAVEVFAEPSGRPNGLAFDPDGR-LLV-ADHGRGL--VRFDPADGEVTvLADEYGKP 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647  82 G-SPTHISTDHQGQFVF--VGSYNAGNvSVTRLEDGlpvGVVDVVegLDGCHSAN---ISPDNRTLWVPALKQDRICLFT 155
Cdd:COG3386    92 LnRPNDGVVDPDGRLYFtdMGEYLPTG-ALYRVDPD---GSLRVL--ADGLTFPNgiaFSPDGRTLYVADTGAGRIYRFD 165

                         170       180
                  ....*....|....*....|...
gi 1230355647 156 VSDDGHLVAQDPAEVTTVEGAGP 178
Cdd:COG3386   166 LDADGTLGNRRVFADLPDGPGGP 188
WD40 COG2319
WD40 repeat [General function prediction only];
7-264 3.62e-04

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 41.82  E-value: 3.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647   7 IASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPeFRVLAYRIApddGALTFAAESALPGSPTH 86
Cdd:COG2319    50 RLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASAD-GTVRLWDLA---TGLLLRTLTGHTGAVRS 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647  87 ISTDHQGQFVFVGSYNaGNVSVTRLEDGLPVGVVDVVEGldGCHSANISPDNRTLwvpalkqdriclFTVSDDGHLV--- 163
Cdd:COG2319   126 VAFSPDGKTLASGSAD-GTVRLWDLATGKLLRTLTGHSG--AVTSVAFSPDGKLL------------ASGSDDGTVRlwd 190

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230355647 164 AQDPAEVTTVEG--AGPRHMVFHPNEQYAYCVNElNSSVDVWELKDPhgniECVQTLDmmpenfSDTRWAADIHITPDGR 241
Cdd:COG2319   191 LATGKLLRTLTGhtGAVRSVAFSPDGKLLASGSA-DGTVRLWDLATG----KLLRTLT------GHSGSVRSVAFSPDGR 259

                         250       260
                  ....*....|....*....|...
gi 1230355647 242 HLYacdrtaslitvfSVSEDGSV 264
Cdd:COG2319   260 LLA------------SGSADGTV 270
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 228-292 5.65e-04

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 41.03  E-value: 5.65e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1230355647 228 TRWAADIHI------TPDGRHLYACDRTASLITVFSVSEDGSVLSKEGF---QPTETQPRGFNVDHSGKYLIAA 292
Cdd:COG3386   130 RVLADGLTFpngiafSPDGRTLYVADTGAGRIYRFDLDADGTLGNRRVFadlPDGPGGPDGLAVDADGNLWVAL 203
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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