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Conserved domains on  [gi|1174754259|gb|OQV22263|]
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eIF-2-alpha kinase activator GCN1 [Hypsibius exemplaris]

Protein Classification

FKBP-type peptidyl-prolyl cis-trans isomerase( domain architecture ID 139723)

FKBP-type peptidyl-prolyl cis-trans isomerase acts as a PPIase that accelerates the folding of proteins

CATH:  3.10.50.40
EC:  5.2.1.8
Gene Ontology:  GO:0003755
SCOP:  4001062

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 1666-1806 5.36e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.08  E-value: 5.36e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1666 DQAEKLKSIPVLHEEGNHLYRKQKYVEAADRYTRALgiledlmgreqpesddwkKLDVLRVPILLNYTQCQLILGHYNEA 1745
Cdd:COG3914     70 AAAALLLLAALLELAALLLQALGRYEEALALYRRAL------------------ALNPDNAEALFNLGNLLLALGRLEEA 131

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1174754259 1746 IEHTTTIIEKDPTNVKAWYRRAKAHAMAWNPKEAREDFARAVELDASLS------GAVQRDLRKLDE 1806
Cdd:COG3914    132 LAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAealnnlGNALQDLGRLEE 198
FKBP_C super family cl19519
FKBP-type peptidyl-prolyl cis-trans isomerase;
1515-1582 7.26e-06

FKBP-type peptidyl-prolyl cis-trans isomerase;


The actual alignment was detected with superfamily member pfam00254:

Pssm-ID: 473184  Cd Length: 94  Bit Score: 46.04  E-value: 7.26e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1174754259 1515 IEAVDETKIKFFYrTVKTSDGTVLDDNFPGKEPLELIYGKQFKLEVWEECLKTMELHEVARFTVQREL 1582
Cdd:pfam00254    3 EKAKKGDRVTVHY-TGTLEDGTVFDSSYDRGKPFEFTLGSGQVIPGWDEGLVGMKVGEKRKLTIPPEL 69
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 1666-1806 5.36e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.08  E-value: 5.36e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1666 DQAEKLKSIPVLHEEGNHLYRKQKYVEAADRYTRALgiledlmgreqpesddwkKLDVLRVPILLNYTQCQLILGHYNEA 1745
Cdd:COG3914     70 AAAALLLLAALLELAALLLQALGRYEEALALYRRAL------------------ALNPDNAEALFNLGNLLLALGRLEEA 131

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1174754259 1746 IEHTTTIIEKDPTNVKAWYRRAKAHAMAWNPKEAREDFARAVELDASLS------GAVQRDLRKLDE 1806
Cdd:COG3914    132 LAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAealnnlGNALQDLGRLEE 198
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 1649-1817 2.61e-06

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 52.29  E-value: 2.61e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1649 IVEASEPGSYEKDSWA-MDQAEKLKSIPVLHEEGNHLYRKQKYVEAADRYTRALGILEDlmgreqpesddwkkldvlrvP 1727
Cdd:TIGR00990  101 VEPADELPEIDESSVAnLSEEERKKYAAKLKEKGNKAYRNKDFNKAIKLYSKAIECKPD--------------------P 160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1728 ILL-NYTQCQLILGHYNEAIEHTTTIIEKDPTNVKAWYRRAKAHAMAWNPKEAREDFARAVELD----ASLSGAVQRDLR 1802
Cdd:TIGR00990  161 VYYsNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLGKYADALLDLTASCIIDgfrnEQSAQAVERLLK 240

                          170
                   ....*....|....*
gi 1174754259 1803 KLDEVQRTRDLEDRE 1817
Cdd:TIGR00990  241 KFAESKAKEILETKP 255
FKBP_C pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase;
1515-1582 7.26e-06

FKBP-type peptidyl-prolyl cis-trans isomerase;


Pssm-ID: 459735  Cd Length: 94  Bit Score: 46.04  E-value: 7.26e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1174754259 1515 IEAVDETKIKFFYrTVKTSDGTVLDDNFPGKEPLELIYGKQFKLEVWEECLKTMELHEVARFTVQREL 1582
Cdd:pfam00254    3 EKAKKGDRVTVHY-TGTLEDGTVFDSSYDRGKPFEFTLGSGQVIPGWDEGLVGMKVGEKRKLTIPPEL 69
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 1741-1811 9.64e-04

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 43.62  E-value: 9.64e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1174754259 1741 HYNEAIEHTTTIIEKDPTNVKAWYRRAKAHAMAWNPKEAREDFARAVELDASLSGAVQRD---LRKLDEVQRTR 1811
Cdd:PLN03088    17 DFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKgtaCMKLEEYQTAK 90
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 1760-1790 1.54e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 37.50  E-value: 1.54e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1174754259 1760 VKAWYRRAKAHAMAWNPKEAREDFARAVELD 1790
Cdd:pfam07719    1 AEALYNLGLAYYKLGDYEEALEAYEKALELD 31
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 1666-1806 5.36e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.08  E-value: 5.36e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1666 DQAEKLKSIPVLHEEGNHLYRKQKYVEAADRYTRALgiledlmgreqpesddwkKLDVLRVPILLNYTQCQLILGHYNEA 1745
Cdd:COG3914     70 AAAALLLLAALLELAALLLQALGRYEEALALYRRAL------------------ALNPDNAEALFNLGNLLLALGRLEEA 131

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1174754259 1746 IEHTTTIIEKDPTNVKAWYRRAKAHAMAWNPKEAREDFARAVELDASLS------GAVQRDLRKLDE 1806
Cdd:COG3914    132 LAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAealnnlGNALQDLGRLEE 198
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
1681-1790 5.54e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 55.78  E-value: 5.54e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1681 GNHLYRKQKYVEAADRYTRALgiledlmgreqpesddwkKLDVLRVPILLNYTQCQLILGHYNEAIEHTTTIIEKDPTNV 1760
Cdd:COG0457     49 GLAYLRLGRYEEALADYEQAL------------------ELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDA 110

                           90       100       110
                   ....*....|....*....|....*....|
gi 1174754259 1761 KAWYRRAKAHAMAWNPKEAREDFARAVELD 1790
Cdd:COG0457    111 EALYNLGLALLELGRYDEAIEAYERALELD 140
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
1657-1790 5.63e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 55.31  E-value: 5.63e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1657 SYEKDSWAMDQAEklksipVLHEEGNHLYRKQKYVEAADRYTRALgiledlmgREQPESddwkkldvlrVPILLNYTQCQ 1736
Cdd:COG4785     62 RIDRALALPDLAQ------LYYERGVAYDSLGDYDLAIADFDQAL--------ELDPDL----------AEAYNNRGLAY 117

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1174754259 1737 LILGHYNEAIEHTTTIIEKDPTNVKAWYRRAKAHAMAWNPKEAREDFARAVELD 1790
Cdd:COG4785    118 LLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELD 171
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 1675-1792 7.72e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 57.31  E-value: 7.72e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1675 PVLHEEGNHLYRKQKYVEAADRYTRALGIledlmgreQPESddwkkldvlrVPILLNYTQCQLILGHYNEAIEHTTTIIE 1754
Cdd:COG3914    113 EALFNLGNLLLALGRLEEALAALRRALAL--------NPDF----------AEAYLNLGEALRRLGRLEEAIAALRRALE 174

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1174754259 1755 KDPTNVKAWYRRAKAHAMAWNPKEAREDFARAVELDAS 1792
Cdd:COG3914    175 LDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPD 212
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
1681-1796 1.18e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 55.01  E-value: 1.18e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1681 GNHLYRKQKYVEAADRYTRALGIledlmgreQPESDDwkkldvlrvpILLNYTQCQLILGHYNEAIEHTTTIIEKDPTNV 1760
Cdd:COG0457     15 GLAYRRLGRYEEAIEDYEKALEL--------DPDDAE----------ALYNLGLAYLRLGRYEEALADYEQALELDPDDA 76

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 1174754259 1761 KAWYRRAKAHAMAWNPKEAREDFARAVELDASLSGA 1796
Cdd:COG0457     77 EALNNLGLALQALGRYEEALEDYDKALELDPDDAEA 112
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 1681-1790 1.85e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.93  E-value: 1.85e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1681 GNHLYRKQKYVEAADRYTRALgiledlmgreqpesddwkKLDVLRVPILLNYTQCQLILGHYNEAIEHTTTIIEKDPTNV 1760
Cdd:COG4235     24 GRAYLRLGRYDEALAAYEKAL------------------RLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                           90       100       110
                   ....*....|....*....|....*....|
gi 1174754259 1761 KAWYRRAKAHAMAWNPKEAREDFARAVELD 1790
Cdd:COG4235     86 EALYLLGLAAFQQGDYAEAIAAWQKLLALL 115
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
1664-1817 7.13e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 52.32  E-value: 7.13e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1664 AMDQAEKLK--SIPVLHEEGNHLYRKQKYVEAADRYTRALGIledlmgreQPESddwkkldvlrVPILLNYTQCQLILGH 1741
Cdd:COG0457     64 DYEQALELDpdDAEALNNLGLALQALGRYEEALEDYDKALEL--------DPDD----------AEALYNLGLALLELGR 125

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1174754259 1742 YNEAIEHTTTIIEKDPTNVKAWYRRAKAHAMAWNPKEAREDFARAVELDASLSGAVQRDLRKLDEVQRTRDLEDRE 1817
Cdd:COG0457    126 YDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLL 201
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 1630-1790 8.09e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 50.73  E-value: 8.09e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1630 YADLDEFLKNPEPLIFTLEIVEASEPGSYEKDSWAMDQAEKLKSIPVLHEEGNHLYRKQKYVEAADRYTRALgiledlmg 1709
Cdd:COG5010     10 LPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQAL-------- 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1710 reqpesddwkKLDVLRVPILLNYTQCQLILGHYNEAIEHTTTIIEKDPTNVKAWYRRAKAHAMAWNPKEAREDFARAVEL 1789
Cdd:COG5010     82 ----------QLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGT 151


                   .
gi 1174754259 1790 D 1790
Cdd:COG5010    152 S 152
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 1633-1794 1.74e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 51.65  E-value: 1.74e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1633 LDEFLKNPEPLIFTLEIVEASepGSYEKdswAMDQAEKL-----KSIPVLHEEGNHLYRKQKYVEAADRYTRALgiledl 1707
Cdd:COG2956    103 LELDPDDAEALRLLAEIYEQE--GDWEK---AIEVLERLlklgpENAHAYCELAELYLEQGDYDEAIEALEKAL------ 171

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1708 mgreqpesddwkKLDVLRVPILLNYTQCQLILGHYNEAIEHTTTIIEKDPTNVKAWYRRAKAHAMAWNPKEAREDFARAV 1787
Cdd:COG2956    172 ------------KLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKAL 239


                   ....*..
gi 1174754259 1788 ELDASLS 1794
Cdd:COG2956    240 ELDPSDD 246
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 1649-1817 2.61e-06

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 52.29  E-value: 2.61e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1649 IVEASEPGSYEKDSWA-MDQAEKLKSIPVLHEEGNHLYRKQKYVEAADRYTRALGILEDlmgreqpesddwkkldvlrvP 1727
Cdd:TIGR00990  101 VEPADELPEIDESSVAnLSEEERKKYAAKLKEKGNKAYRNKDFNKAIKLYSKAIECKPD--------------------P 160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1728 ILL-NYTQCQLILGHYNEAIEHTTTIIEKDPTNVKAWYRRAKAHAMAWNPKEAREDFARAVELD----ASLSGAVQRDLR 1802
Cdd:TIGR00990  161 VYYsNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLGKYADALLDLTASCIIDgfrnEQSAQAVERLLK 240

                          170
                   ....*....|....*
gi 1174754259 1803 KLDEVQRTRDLEDRE 1817
Cdd:TIGR00990  241 KFAESKAKEILETKP 255
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 1664-1791 2.83e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 48.65  E-value: 2.83e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1664 AMDQAEKL--KSIPVLHEEGNHLYRKQKYVEAADRYTRALgiledlmgREQPESDDwkkldvlrvpILLNYTQCQLILGH 1741
Cdd:COG4783     26 LLEKALELdpDNPEAFALLGEILLQLGDLDEAIVLLHEAL--------ELDPDEPE----------ARLNLGLALLKAGD 87

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1742 YNEAIEHTTTIIEKDPTNVKAWYRRAKAHAMAWNPKEAREDFARAVELDA 1791
Cdd:COG4783     88 YDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
1684-1793 4.41e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 46.70  E-value: 4.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1684 LYRKQKYVEAADRYTRALgiledlmgreqpesddwkKLDVLRVPILLNYTQCQLILGHYNEAIEHTTTIiEKDPTNVKAW 1763
Cdd:COG3063      2 YLKLGDLEEAEEYYEKAL------------------ELDPDNADALNNLGLLLLEQGRYDEAIALEKAL-KLDPNNAEAL 62

                           90       100       110
                   ....*....|....*....|....*....|
gi 1174754259 1764 YRRAKAHAMAWNPKEAREDFARAVELDASL 1793
Cdd:COG3063     63 LNLAELLLELGDYDEALAYLERALELDPSA 92
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
1720-1806 6.45e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 49.62  E-value: 6.45e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1720 KLDVLRVPILLNYTQCQLILGHYNEAIEHTTTIIEKDPTNVKAWYRRAKAHAMAWNPKEAREDFARAVELDASLS----- 1794
Cdd:COG0457      2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAealnn 81

                           90
                   ....*....|...
gi 1174754259 1795 -GAVQRDLRKLDE 1806
Cdd:COG0457     82 lGLALQALGRYEE 94
FKBP_C pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase;
1515-1582 7.26e-06

FKBP-type peptidyl-prolyl cis-trans isomerase;


Pssm-ID: 459735  Cd Length: 94  Bit Score: 46.04  E-value: 7.26e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1174754259 1515 IEAVDETKIKFFYrTVKTSDGTVLDDNFPGKEPLELIYGKQFKLEVWEECLKTMELHEVARFTVQREL 1582
Cdd:pfam00254    3 EKAKKGDRVTVHY-TGTLEDGTVFDSSYDRGKPFEFTLGSGQVIPGWDEGLVGMKVGEKRKLTIPPEL 69
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 1684-1796 8.15e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.65  E-value: 8.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1684 LYRKQKYVEAADRYTRALGILEDLMGREQPESDDWKKLDVLRVPILLNYTQCQLILGHYNEAIEHTTTIIEKDPTNVKAW 1763
Cdd:COG5010     12 LYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELY 91

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1174754259 1764 YRRAKAHAMAWNPKEAREDFARAVELDASLSGA 1796
Cdd:COG5010     92 YNLALLYSRSGDKDEAKEYYEKALALSPDNPNA 124
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 1729-1790 2.40e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.87  E-value: 2.40e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1174754259 1729 LLNYTQCQLILGHYNEAIEHTTTIIEKDPTNVKAWYRRAKAHAMAWNPKEAREDFARAVELD 1790
Cdd:COG4783      7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELD 68
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 1684-1804 3.80e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.90  E-value: 3.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1684 LYRKQKYVEAADRYTRALgiledlmgREQPESDdwkkldvLRVPILLNYTQCQLILGHYNEAIEHTTTIIEKDPTNVK-- 1761
Cdd:COG1729      3 LLKAGDYDEAIAAFKAFL--------KRYPNSP-------LAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKap 67

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 1174754259 1762 -AWYRRAKAHAMAWNPKEAREDFARAVEL--DASLSGAVQRDLRKL 1804
Cdd:COG1729     68 dALLKLGLSYLELGDYDKARATLEELIKKypDSEAAKEARARLARL 113
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 1666-1815 4.51e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 44.33  E-value: 4.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1666 DQAEKL---------KSIPVLHEEGNHLYRKQKYVEAADRYTRALgiledlmgREQPESddwkkldvlrVPILLNYTQCQ 1736
Cdd:COG2956     93 DRAEELleklleldpDDAEALRLLAEIYEQEGDWEKAIEVLERLL--------KLGPEN----------AHAYCELAELY 154

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1174754259 1737 LILGHYNEAIEHTTTIIEKDPTNVKAWYRRAKAHAMAWNPKEAREDFARAVELDASLSGAVQRDLRKLDEVQRTRDLED 1815
Cdd:COG2956    155 LEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALE 233
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 1702-1790 9.48e-04

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 44.20  E-value: 9.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174754259 1702 GILEDLMGREQPESDDWKKLDVLRVPILLNYTQCQLI---LGHYNEAIEHTTTIIEKDPTNVKAWYRRAKAHAMAWNPKE 1778
Cdd:TIGR00990  338 GTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMnleLGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQ 417

                           90
                   ....*....|..
gi 1174754259 1779 AREDFARAVELD 1790
Cdd:TIGR00990  418 AGKDYQKSIDLD 429
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 1741-1811 9.64e-04

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 43.62  E-value: 9.64e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1174754259 1741 HYNEAIEHTTTIIEKDPTNVKAWYRRAKAHAMAWNPKEAREDFARAVELDASLSGAVQRD---LRKLDEVQRTR 1811
Cdd:PLN03088    17 DFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKgtaCMKLEEYQTAK 90
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 1760-1790 1.54e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 37.50  E-value: 1.54e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1174754259 1760 VKAWYRRAKAHAMAWNPKEAREDFARAVELD 1790
Cdd:pfam07719    1 AEALYNLGLAYYKLGDYEEALEAYEKALELD 31
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 1744-1790 2.03e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.99  E-value: 2.03e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 1174754259 1744 EAIEHTTTIIEKDPTNVKAWYRRAKAHAMAWNPKEAREDFARAVELD 1790
Cdd:COG4235      1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLD 47
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
1735-1796 5.59e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.84  E-value: 5.59e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1174754259 1735 CQLILGHYNEAIEHTTTIIEKDPTNVKAWYRRAKAHAMAWNPKEAREdFARAVELDASLSGA 1796
Cdd:COG3063      1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEA 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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