|
Name |
Accession |
Description |
Interval |
E-value |
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
1-1031 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 1131.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 1 MLNNIIKFSLNNKLFILLGAVLLIVGGTYTFQKMDVDVFPDLTAPTVVLMTDAHGMAPEEVERLVSFPIETAVNGATDVR 80
Cdd:COG3696 1 MLNRIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 81 RVRSASLQGYSFVWVEFEWGTNIFKARQIVSEKMGTLTSSLPVGIIPVLAPQSSLMGEILFVGLQADST--SMMELRTLA 158
Cdd:COG3696 81 EVRSISRFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPELGPISTGLGEIYQYTLESDPGkySLMELRTLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 159 DWIVKPAILATGGVSQVTIIGGDYKQYQILADPVKMNAYGVTLQELKSVGKTLSTNSTGGIIRDYGNEYALRGMARTNDL 238
Cdd:COG3696 161 DWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 239 EELGETYVKTRNGRPVVLSDVAEIVIGTPVKMGHASQNAK-PSVILAISKQPNINTLNVTERIEYNLAEIKKTFPADVRM 317
Cdd:COG3696 241 EDIENIVVKTRNGTPVLLRDVAEVRIGPAPRRGAATLNGEgEVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPEGVKI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 318 DTkIFRQADFIEASVNNVGIALMEGAIFVIIILFIFLASFRTTIISVIAIPLSLFGTLIVLYLLGMNINTMTLGGMCIAI 397
Cdd:COG3696 321 VP-FYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAIDF 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 398 GSLVDDAIIDVENVYKRLRQNhiKPKEERESVVSVIYKASVEIRASILNATFIIIVAFIPLFFLSGMEGRMLKPLGVAYI 477
Cdd:COG3696 400 GIIVDGAVVMVENILRRLEEN--RAAGTPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMALTVI 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 478 VSLFMSLVVAMTITPLLCRMMLSRDnyldKKTKDNWLTQKLSTLYERSLLWVLTNKKIVIYPTIALLLVAGVLFVTMGRS 557
Cdd:COG3696 478 FALLGALLLSLTLVPVLASLLLRGK----VPEKENPLVRWLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPRLGSE 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 558 FLPEFNEGSLTISAVTKPGVTLDESDRLGNLIETELLLLPEVTSTARRTGRGELDEHSLSTNSAEIDVNFTLGK-----R 632
Cdd:COG3696 554 FLPELDEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVESVVSRTGRAEDATDPMGVNMSETFVILKPRSewrsgR 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 633 GREEFMAEVREKLGAVPGLAFTVGQPLGHRIDHMLSGTRANIAIKLFGTDLSQMFMIANQIKGSIIGIDGLVDVAVEQQT 712
Cdd:COG3696 634 TKEELIAEMREALEQIPGVNFNFSQPIQMRVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVERVT 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 713 ETPQLQVRAKRSMLAQYGISIEDFNEFIELAFAGEKLSEIYEGQRSFDLVLKLNKSYTENIEQVKSALIDTQNGKKVPLE 792
Cdd:COG3696 714 GLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLS 793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 793 EVAEIVSVGGPNSISRENVQRKIVVSANVAGRDLNGVVGEIKANIESQINLPQGYRVEYGGQFESAKSASRTLLITSILA 872
Cdd:COG3696 794 QVADIEVVEGPNQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVAEQVKLPPGYYIEWGGQFENLQRATARLAIVVPLA 873
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 873 ICVIFLLLYSEFKNVSLSAIVLVNLPLALIGGVFAVWITSGIISIPSIIGFITLFGIATRNGILLISKYQHMEHTDDSLT 952
Cdd:COG3696 874 LLLIFLLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEGLDLR 953
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1082435988 953 KTIVAGSLDRLNPILMTALTAALALIPLVLNGDkSGNEIQSPMAVVVLGGLLTSTLLNIYIVPIAYEILQNRRLKKEQQ 1031
Cdd:COG3696 954 EAIIEGALERLRPVLMTALVAALGLLPMALSTG-PGSEVQRPLATVVIGGLITSTLLTLLVLPALYLLFGRRRLRRAAA 1031
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
5-1018 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 739.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 5 IIKFSLNNKLFILLGAVLLIVGGTYTFQKMDVDVFPDLTAPTVVLMTDAHGMAPEEVERLVSFPIETAVNGATDVRRVRS 84
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 85 ASLQGYSFVWVEFEWGTNIFKARQIVSEKMGTLTSSLPVGII-PVLAPQSSLMGEILFVGLQADSTSM--MELRTLADWI 161
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQrPGISVIKTSLGPIMVLAVTSPDGSYtqTDLRDYADTN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 162 VKPAILATGGVSQVTIIGGDYKQYQILADPVKMNAYGVTLQELKSVGKTLSTNSTGGIIRDYGNEYALRGMARTNDLEEL 241
Cdd:pfam00873 161 IKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAEDF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 242 GETYVKTRNGRPVVLSDVAEIVIGTPVKMGHASQNAKPSVILAISKQPNINTLNVTERIEYNLAEIKKTFPADVRMdTKI 321
Cdd:pfam00873 241 EKIIVKNQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGVEI-VVV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 322 FRQADFIEASVNNVGIALMEGAIFVIIILFIFLASFRTTIISVIAIPLSLFGTLIVLYLLGMNINTMTLGGMCIAIGSLV 401
Cdd:pfam00873 320 YDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 402 DDAIIDVENVYKRLRQNHIKPKEeresvvsVIYKASVEIRASILNATFIIIVAFIPLFFLSGMEGRMLKPLGVAYIVSLF 481
Cdd:pfam00873 400 DDAIVVVENIERVLEENGLKPLE-------AAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 482 MSLVVAMTITPLLCRMMLSRDNYLDKKTKDNWLTQ---KLSTLYERSLLWVLTNKKIVIypTIALLLVAG--VLFVTMGR 556
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRREPKHGGFFRWFNRmfdRLTRGYAKLLAKVLRHTAVVL--LVALLLVVGsvWLFVRIPT 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 557 SFLPEFNEGSLTISAVTKPGVTLDESDRLGNLIETELLLLPEVTSTARRTGRGElDEHSLSTNSAEIDVNF------TLG 630
Cdd:pfam00873 551 EFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAF-SGDNNGPNSGDAFISLkpwkerPGP 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 631 KRGREEFMAEVREKLGAVPGLAFTVGQPLGHRIDHMLSGTRANIAIKLFGTDLSQMFMIANQIKGSIIGIDGLVDVAVEQ 710
Cdd:pfam00873 630 EKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSDG 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 711 QTETPQLQVRAKRSMLAQYGISIEDFNEFIELAFAGEKLSEIYEGQRSFDLVLKLNKSYTENIEQVKSALIDTQNGKKVP 790
Cdd:pfam00873 710 QEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMIP 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 791 LEEVAEIVSVGGPNSISRENVQRKIVVSANVAGRDLNGVVGEIKANIESQINLPQGYRVEYGGQFESAKSASRTLLITSI 870
Cdd:pfam00873 790 LSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPILIA 869
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 871 LAICVIFLLLYSEFKNVSLSAIVLVNLPLALIGGVFAVWITSGIISIPSIIGFITLFGIATRNGILLISKY-QHMEHTDD 949
Cdd:pfam00873 870 LALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFAnELREQEGK 949
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 950 SLTKTIVAGSLDRLNPILMTALTAALALIPLVL-NGDksGNEIQSPMAVVVLGGLLTSTLLNIYIVPIAY 1018
Cdd:pfam00873 950 SLEEAILEACRLRLRPILMTALAAILGVLPLALsTGA--GSELQQPLGIVVFGGLVTSTVLTLLVVPVFY 1017
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
1-1029 |
0e+00 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 637.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 1 MLNNIIKFSLNNKLFILLGAVLLIVGGTYTFQKMDVDVFPDLTAPTVVLMTDAHGMAPEEVERLVSFPIETAVNGATDVR 80
Cdd:TIGR00914 1 MIERIISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 81 RVRSASLQGYSFVWVEFEWGTNIFKARQIVSEKMGTLTSSLPVGIIPVLAPQSSLMGEILFVGLQADSTS---------M 151
Cdd:TIGR00914 81 TTRSLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTGLGEIFLYTVEAEEGArkkdggaytL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 152 MELRTLADWIVKPAILATGGVSQVTIIGGDYKQYQILADPVKMNAYGVTLQELKSVGKTLSTNSTGGIIRDYGNEYALRG 231
Cdd:TIGR00914 161 TDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 232 MARTNDLEELGETYVKTRNGRPVVLSDVAEIVIGTPVKMGHASQNAKP----SVILAISKqpniNTLNVTERIEYNLAEI 307
Cdd:TIGR00914 241 PGQVQSMDDIRNIVIATGEGVPIRIRDVARVQIGKELRTGAATENGKEvvlgTVFMLIGE----NSRTVAQAVGDKLETI 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 308 KKTFPADVRMDTkIFRQADFIEASVNNVGIALMEGAIFVIIILFIFLASFRTTIISVIAIPLSLFGTLIVLYLLGMNINT 387
Cdd:TIGR00914 317 NKTLPEGVEIVT-TYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANL 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 388 MTLGGmcIAIGSLVDDAIIDVENVYKRL--RQNHIKPKEERESVVSVIYKASVEIRASILNATFIIIVAFIPLFFLSGME 465
Cdd:TIGR00914 396 MSLGA--LDFGLIVDGAVVIVENAHRRLaeAQHHHGRQLTLKERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVE 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 466 GRMLKPLGVAYIVSLFMSLVVAMTITPLLCRMMLSRDnyldKKTKDNWLTQKLSTLYERSLLWVLTNKKIVIYPTIALLL 545
Cdd:TIGR00914 474 GKMFHPMAFTVVLALAGAMILSLTFVPAAVALFIRGK----VAEKENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIV 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 546 VAGVLFVTMGRSFLPEFNEGSLTISAVTKPGVTLDESDRLGNLIETELLLLPEVTSTARRTGRGELDEHSLSTNSAEIDV 625
Cdd:TIGR00914 550 LVVWIASRVGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGTAEIATDPMPPNASDTYI 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 626 ------NFTLGKRGREEFMAEVREKLGAVPGLAFTVGQPLGHRIDHMLSGTRANIAIKLFGTDLSQMFMIANQIKGSIIG 699
Cdd:TIGR00914 630 ilkpesQWPEGKKTKEDLIEEIQEATVRIPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKG 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 700 IDGLVDVAVEQQTETPQLQVRAKRSMLAQYGISIEDFNEFIELAFAGEKLSEIYEGQRSFDLVLKLNKSYTENIEQVKSA 779
Cdd:TIGR00914 710 VPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQL 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 780 LIDTQNGK-----KVPLEEVAEIVSVGGPNSISRENVQRKIVVSANVAGRDLNGVVGEIKANIESQINLPQGYRVEYGGQ 854
Cdd:TIGR00914 790 PIPLPLSEdarkqFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQ 869
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 855 FESAKSASRTLLITSILAICVIFLLLYSEFKNVSLSAIVLVNLPLALIGGVFAVWITSGIISIPSIIGFITLFGIATRNG 934
Cdd:TIGR00914 870 FEQLQSATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNG 949
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 935 ILLISKYQHMEHTDDSLTKTIVAGSLDRLNPILMTALTAALALIPLVLnGDKSGNEIQSPMAVVVLGGLLTSTLLNIYIV 1014
Cdd:TIGR00914 950 LVMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAI-ATGTGAEVQRPLATVVIGGIITATLLTLFVL 1028
|
1050
....*....|....*
gi 1082435988 1015 PIAYEILQNRRLKKE 1029
Cdd:TIGR00914 1029 PALYRLVHRRRHKGR 1043
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
21-1021 |
8.50e-140 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 445.23 E-value: 8.50e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 21 VLLIVGGTYTFQKMDVDVFPDLTAPTVVLMTDAHGMAPEEVERLVSFPIETAVNGATDVRRVRSASLQGYSFVWVEFEWG 100
Cdd:NF033617 16 LLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSLGYSTITLQFRLG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 101 TNIFKARQIVSEKMGTLTSSLPVGI--IPVLAPQSSLMGEILFVGLQADSTSMMELRTLADWIVKPAILATGGVSQVTII 178
Cdd:NF033617 96 TDLDVALSEVQAAINAAQSLLPSEApdPPVYRKANSADTPIMYIGLTSEEMPRGQLTDYAERVLAPKLSQINGVGSVDVS 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 179 GGDYKQYQILADPVKMNAYGVTLQELKSVGKTLSTNSTGGIIRDYGNEYALRGMARTNDLEELGETYVK-TRNGRPVVLS 257
Cdd:NF033617 176 GGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYEDLVIKyADNGAPVRLG 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 258 DVAEIVIGTPVKMGHASQNAKPSVILAISKQPNINTLNVTERIEYNLAEIKKTFPADVRMDTkIFRQADFIEASVNNVGI 337
Cdd:NF033617 256 DVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIKVNV-LYDRTRFIRASIDEVES 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 338 ALMEGAIFVIIILFIFLASFRTTIISVIAIPLSLFGTLIVLYLLGMNINTMTLGGMCIAIGSLVDDAIIDVENVYKrlrq 417
Cdd:NF033617 335 TLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDDAIVVVENIHR---- 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 418 nHIkpkEERESVVSVIYKASVEIRASILNATFIIIVAFIPLFFLSGMEGRMLKPLGVAYIVSLFMSLVVAMTITPLLC-R 496
Cdd:NF033617 411 -HI---EEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLTPMMCsR 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 497 MMLSRDNYLDKKTKDNWLTQKLSTLYERSLLWVLTNKKIVIYPTIALLLVAGVLFVTMGRSFLPEFNEGSLTISAVTKPG 576
Cdd:NF033617 487 LLKANEKPGRFARAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVIFGMIQAPQS 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 577 VTLDESDRLGNLIETELLLLPEVTSTARRTGRGELDehslSTNSAEIDVNFT-LGKRGR--EEFMAEVREKLGAVPGLAF 653
Cdd:NF033617 567 ISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGGNP----GDNTGFGIINLKpWDERDVsaQEIIDRLRPKLAKVPGMDL 642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 654 TVGQplghrIDHMLSGTRANIAIKLF---GTDLSQMFMIANQIKGSIIGIDGLVDVAVEQQTETPQLQVRAKRSMLAQYG 730
Cdd:NF033617 643 FLFP-----LQDLPGGAGSSLPQYQVtltPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDIDRDKAARLG 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 731 ISIEDFNEFIELAFAGEKLSEIYEGQRSFDLVLKLNKSYTENIEQVKSALIDTQNGKKVPLEEVAEIVSVGGPNSISREN 810
Cdd:NF033617 718 ISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLSTLAKIEERAAPLSLNHFN 797
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 811 VQRKIVVSANVAGRDLNGVVGEIKANIESQInLPQGYRVEYGGQFESAKSASRTLLITSILAICVIFLLLYSEFKNVSLS 890
Cdd:NF033617 798 QFNSATLSFNLAPGVSLGEAIEALDQAAKEL-LPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAIQYESFVDP 876
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 891 AIVLVNLPLALIGGVFAVWITSGIISIPSIIGFITLFGIATRNGILLIS---KYQHmeHTDDSLTKTIVAGSLDRLNPIL 967
Cdd:NF033617 877 LTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEfanELQR--HQGLSRREAIYQAAALRLRPIL 954
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....
gi 1082435988 968 MTALTAALALIPLVLNGDkSGNEIQSPMAVVVLGGLLTSTLLNIYIVPIAYEIL 1021
Cdd:NF033617 955 MTTLAMLLGAIPLMLSTG-AGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLL 1007
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
14-1031 |
1.15e-65 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 240.40 E-value: 1.15e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 14 LFI------LLGAVLLIVGGTYTFQKMDVDVFPDLTAPTVVLMTDAHGMAPEEVERLVSFPIETAVNGATDVRRVRSASL 87
Cdd:PRK10614 6 LFIyrpvatILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 88 QGYSFVWVEFEWGTNIFKARQIVSEKMGTLTSSLPVGII---------PVLAPqsslmgeILFVGLQADSTSMMELRTLA 158
Cdd:PRK10614 86 LGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPsrptyrkanPSDAP-------IMILTLTSDTYSQGQLYDFA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 159 DWIVKPAILATGGVSQVTIIGGDYKQYQILADPVKMNAYGVTLQELKSVGKTLSTNSTGGIIRDYGNEYALRgmarTNDL 238
Cdd:PRK10614 159 STQLAQTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQ----TNDE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 239 EELGETY----VKTRNGRPVVLSDVAEIVIGTPVKMGHASQNAKPSVILAISKQPNINTLNVTERIEYNLAEIKKTFPAD 314
Cdd:PRK10614 235 LKTAAEYqpliIHYNNGAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPAA 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 315 VRMDTKIFRQADfIEASVNNVGIALMEGAIFVIIILFIFLASFRTTIISVIAIPLSLFGTLIVLYLLGMNINTMTLGGMC 394
Cdd:PRK10614 315 IDLQIAQDRSPT-IRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALT 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 395 IAIGSLVDDAIIDVENVYKRLrQNHIKPKEeresvvsVIYKASVEIRASILNATFIIIVAFIPLFFLSGMEGRMLKPLGV 474
Cdd:PRK10614 394 IATGFVVDDAIVVLENISRHL-EAGMKPLQ-------AALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAV 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 475 AYIVSLFMSLVVAMTITPLLCRMML--SRDNYLDKKTKDNWLTQKLSTLYERSLLWVLTNKKIVIYPTIALLLVAGVLFV 552
Cdd:PRK10614 466 TLSVAIGISLLVSLTLTPMMCAWLLksSKPREQKRLRGFGRMLVALQQGYGRSLKWVLNHTRWVGVVLLGTIALNVWLYI 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 553 TMGRSFLPEFNEGSLTisavtkPGVTLDES-------DRLGNLIETeLLLLPEVTSTARRTGRGEldehslsTNSAEIDV 625
Cdd:PRK10614 546 SIPKTFFPEQDTGRLM------GFIQADQSisfqamrGKLQDFMKI-IRDDPAVDNVTGFTGGSR-------VNSGMMFI 611
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 626 NFT-LGKRGR--EEFMAEVREKLGAVPG--LAFTVGQplghriDHMLSGTRANIAIK--LFGTDLSQMFMIANQIKGSII 698
Cdd:PRK10614 612 TLKpLSERSEtaQQVIDRLRVKLAKEPGanLFLMAVQ------DIRVGGRQSNASYQytLLSDDLAALREWEPKIRKALA 685
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 699 GIDGLVDVAVEQQTETPQLQVRAKRSMLAQYGISIEDFNEFIELAFAGEKLSEIYEGQRSFDLVLKLNKSYTENIEQVKS 778
Cdd:PRK10614 686 ALPELADVNSDQQDKGAEMALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEK 765
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 779 ALIDTQNGKKVPLEEVAEIVSVGGPNSISRENVQRKIVVSANVA-GRDLNGVVGEIKANIeSQINLPQGYRVEYGGQFES 857
Cdd:PRK10614 766 MFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPtGKSLSDASAAIERAM-TQLGVPSTVRGSFAGTAQV 844
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 858 AKSASRTLLITSILAICVIFLLLYSEFKNVSLSAIVLVNLPLALIGGVFAVWITSGIISIPSIIGFITLFGIATRNGILL 937
Cdd:PRK10614 845 FQETMNSQLILILAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMM 924
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 938 ISKYQHMEHTDD-SLTKTIVAGSLDRLNPILMTALTAALALIPLVL-NGDksGNEIQSPMAVVVLGGLLTSTLLNIYIVP 1015
Cdd:PRK10614 925 VDFALEAQRNGNlTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLsGGD--GAELRQPLGITIVGGLVMSQLLTLYTTP 1002
|
1050
....*....|....*.
gi 1082435988 1016 IAYEILQNRRLKKEQQ 1031
Cdd:PRK10614 1003 VVYLFFDRLRLRFSRK 1018
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
1-1031 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 1131.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 1 MLNNIIKFSLNNKLFILLGAVLLIVGGTYTFQKMDVDVFPDLTAPTVVLMTDAHGMAPEEVERLVSFPIETAVNGATDVR 80
Cdd:COG3696 1 MLNRIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 81 RVRSASLQGYSFVWVEFEWGTNIFKARQIVSEKMGTLTSSLPVGIIPVLAPQSSLMGEILFVGLQADST--SMMELRTLA 158
Cdd:COG3696 81 EVRSISRFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPELGPISTGLGEIYQYTLESDPGkySLMELRTLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 159 DWIVKPAILATGGVSQVTIIGGDYKQYQILADPVKMNAYGVTLQELKSVGKTLSTNSTGGIIRDYGNEYALRGMARTNDL 238
Cdd:COG3696 161 DWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 239 EELGETYVKTRNGRPVVLSDVAEIVIGTPVKMGHASQNAK-PSVILAISKQPNINTLNVTERIEYNLAEIKKTFPADVRM 317
Cdd:COG3696 241 EDIENIVVKTRNGTPVLLRDVAEVRIGPAPRRGAATLNGEgEVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPEGVKI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 318 DTkIFRQADFIEASVNNVGIALMEGAIFVIIILFIFLASFRTTIISVIAIPLSLFGTLIVLYLLGMNINTMTLGGMCIAI 397
Cdd:COG3696 321 VP-FYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAIDF 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 398 GSLVDDAIIDVENVYKRLRQNhiKPKEERESVVSVIYKASVEIRASILNATFIIIVAFIPLFFLSGMEGRMLKPLGVAYI 477
Cdd:COG3696 400 GIIVDGAVVMVENILRRLEEN--RAAGTPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMALTVI 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 478 VSLFMSLVVAMTITPLLCRMMLSRDnyldKKTKDNWLTQKLSTLYERSLLWVLTNKKIVIYPTIALLLVAGVLFVTMGRS 557
Cdd:COG3696 478 FALLGALLLSLTLVPVLASLLLRGK----VPEKENPLVRWLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPRLGSE 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 558 FLPEFNEGSLTISAVTKPGVTLDESDRLGNLIETELLLLPEVTSTARRTGRGELDEHSLSTNSAEIDVNFTLGK-----R 632
Cdd:COG3696 554 FLPELDEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVESVVSRTGRAEDATDPMGVNMSETFVILKPRSewrsgR 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 633 GREEFMAEVREKLGAVPGLAFTVGQPLGHRIDHMLSGTRANIAIKLFGTDLSQMFMIANQIKGSIIGIDGLVDVAVEQQT 712
Cdd:COG3696 634 TKEELIAEMREALEQIPGVNFNFSQPIQMRVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVERVT 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 713 ETPQLQVRAKRSMLAQYGISIEDFNEFIELAFAGEKLSEIYEGQRSFDLVLKLNKSYTENIEQVKSALIDTQNGKKVPLE 792
Cdd:COG3696 714 GLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLS 793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 793 EVAEIVSVGGPNSISRENVQRKIVVSANVAGRDLNGVVGEIKANIESQINLPQGYRVEYGGQFESAKSASRTLLITSILA 872
Cdd:COG3696 794 QVADIEVVEGPNQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVAEQVKLPPGYYIEWGGQFENLQRATARLAIVVPLA 873
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 873 ICVIFLLLYSEFKNVSLSAIVLVNLPLALIGGVFAVWITSGIISIPSIIGFITLFGIATRNGILLISKYQHMEHTDDSLT 952
Cdd:COG3696 874 LLLIFLLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEGLDLR 953
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1082435988 953 KTIVAGSLDRLNPILMTALTAALALIPLVLNGDkSGNEIQSPMAVVVLGGLLTSTLLNIYIVPIAYEILQNRRLKKEQQ 1031
Cdd:COG3696 954 EAIIEGALERLRPVLMTALVAALGLLPMALSTG-PGSEVQRPLATVVIGGLITSTLLTLLVLPALYLLFGRRRLRRAAA 1031
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
5-1018 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 739.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 5 IIKFSLNNKLFILLGAVLLIVGGTYTFQKMDVDVFPDLTAPTVVLMTDAHGMAPEEVERLVSFPIETAVNGATDVRRVRS 84
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 85 ASLQGYSFVWVEFEWGTNIFKARQIVSEKMGTLTSSLPVGII-PVLAPQSSLMGEILFVGLQADSTSM--MELRTLADWI 161
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQrPGISVIKTSLGPIMVLAVTSPDGSYtqTDLRDYADTN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 162 VKPAILATGGVSQVTIIGGDYKQYQILADPVKMNAYGVTLQELKSVGKTLSTNSTGGIIRDYGNEYALRGMARTNDLEEL 241
Cdd:pfam00873 161 IKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAEDF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 242 GETYVKTRNGRPVVLSDVAEIVIGTPVKMGHASQNAKPSVILAISKQPNINTLNVTERIEYNLAEIKKTFPADVRMdTKI 321
Cdd:pfam00873 241 EKIIVKNQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGVEI-VVV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 322 FRQADFIEASVNNVGIALMEGAIFVIIILFIFLASFRTTIISVIAIPLSLFGTLIVLYLLGMNINTMTLGGMCIAIGSLV 401
Cdd:pfam00873 320 YDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 402 DDAIIDVENVYKRLRQNHIKPKEeresvvsVIYKASVEIRASILNATFIIIVAFIPLFFLSGMEGRMLKPLGVAYIVSLF 481
Cdd:pfam00873 400 DDAIVVVENIERVLEENGLKPLE-------AAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 482 MSLVVAMTITPLLCRMMLSRDNYLDKKTKDNWLTQ---KLSTLYERSLLWVLTNKKIVIypTIALLLVAG--VLFVTMGR 556
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRREPKHGGFFRWFNRmfdRLTRGYAKLLAKVLRHTAVVL--LVALLLVVGsvWLFVRIPT 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 557 SFLPEFNEGSLTISAVTKPGVTLDESDRLGNLIETELLLLPEVTSTARRTGRGElDEHSLSTNSAEIDVNF------TLG 630
Cdd:pfam00873 551 EFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAF-SGDNNGPNSGDAFISLkpwkerPGP 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 631 KRGREEFMAEVREKLGAVPGLAFTVGQPLGHRIDHMLSGTRANIAIKLFGTDLSQMFMIANQIKGSIIGIDGLVDVAVEQ 710
Cdd:pfam00873 630 EKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSDG 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 711 QTETPQLQVRAKRSMLAQYGISIEDFNEFIELAFAGEKLSEIYEGQRSFDLVLKLNKSYTENIEQVKSALIDTQNGKKVP 790
Cdd:pfam00873 710 QEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMIP 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 791 LEEVAEIVSVGGPNSISRENVQRKIVVSANVAGRDLNGVVGEIKANIESQINLPQGYRVEYGGQFESAKSASRTLLITSI 870
Cdd:pfam00873 790 LSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPILIA 869
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 871 LAICVIFLLLYSEFKNVSLSAIVLVNLPLALIGGVFAVWITSGIISIPSIIGFITLFGIATRNGILLISKY-QHMEHTDD 949
Cdd:pfam00873 870 LALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFAnELREQEGK 949
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 950 SLTKTIVAGSLDRLNPILMTALTAALALIPLVL-NGDksGNEIQSPMAVVVLGGLLTSTLLNIYIVPIAY 1018
Cdd:pfam00873 950 SLEEAILEACRLRLRPILMTALAAILGVLPLALsTGA--GSELQQPLGIVVFGGLVTSTVLTLLVVPVFY 1017
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
4-1028 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 683.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 4 NIIKFSLNNKLFILLGAVLLIVGGTYTFQKMDVDVFPDLTAPTVVLMTDAHGMAPEEVERLVSFPIETAVNGATDVRRVR 83
Cdd:COG0841 2 NLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYIT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 84 SASLQGYSFVWVEFEWGTNIFKARQIVSEKMGTLTSSLPVGII-PVLAPQSSLMGEILFVGLQADSTSMMELRTLADWIV 162
Cdd:COG0841 82 STSSEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEpPGVTKVNPSDFPVMVLALSSDDLDELELSDYAERNI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 163 KPAILATGGVSQVTIIGGDYKQYQILADPVKMNAYGVTLQELKSVGKTLSTNSTGGIIRDYGNEYALRGMARTNDLEELG 242
Cdd:COG0841 162 KDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGRLKTPEEFE 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 243 ETYVKTRNGRPVVLSDVAEIVIGTPVKMGHASQNAKPSVILAISKQPNINTLNVTERIEYNLAEIKKTFPADVRMDTkIF 322
Cdd:COG0841 242 NIVIRTNDGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPEGVELTI-VY 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 323 RQADFIEASVNNVGIALMEGAIFVIIILFIFLASFRTTIISVIAIPLSLFGTLIVLYLLGMNINTMTLGGMCIAIGSLVD 402
Cdd:COG0841 321 DQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLAIGIVVD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 403 DAIIDVENVYkRLRQNHIKPKEeresvvsVIYKASVEIRASILNATFIIIVAFIPLFFLSGMEGRMLKPLGVAYIVSLFM 482
Cdd:COG0841 401 DAIVVVENIE-RHMEEGLSPLE-------AAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALLI 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 483 SLVVAMTITPLLCRMMLSRDNYLDKK---TKDNWLTQKLSTLYERSLLWVLTNKKIVIYPTIALLLVAGVLFVTMGRSFL 559
Cdd:COG0841 473 SLFVALTLTPALCARLLKPHPKGKKGrffRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFF 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 560 PEFNEGSLTISAVTKPGVTLDESDRLGNLIETELLLLPEVTSTARRTGRGEldeHSLSTNSAEIDVNFT-LGKRGR--EE 636
Cdd:COG0841 553 PEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSG---GGSGSNSGTIFVTLKpWDERDRsaDE 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 637 FMAEVREKLGAVPGLAFTVGQPlghriDHMLSGTRANIAIKLFGTDLSQMFMIANQIKGSIIGIDGLVDVAVEQQTETPQ 716
Cdd:COG0841 630 IIARLREKLAKIPGARVFVFQP-----PAGGLGSGAPIEVQLQGDDLEELAAAAEKLLAALRQIPGLVDVRSDLQLGKPE 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 717 LQVRAKRSMLAQYGISIEDFNEFIELAFAGEKLSEIYEGQRSFDLVLKLNKSYTENIEQVKSALIDTQNGKKVPLEEVAE 796
Cdd:COG0841 705 LQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMVPLSSVAT 784
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 797 IVSVGGPNSISRENVQRKIVVSANVA-GRDLNGVVGEIKANIeSQINLPQGYRVEYGGQFESAKSASRTLLITSILAICV 875
Cdd:COG0841 785 IEEGTGPSSINRYNGQRSVTVSANLApGVSLGEALAAIEELA-AELKLPPGVSIEFTGQAEEEQESFSSLGLAFLLALLL 863
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 876 IFLLLYSEFKNVSLSAIVLVNLPLALIGGVFAVWITSGIISIPSIIGFITLFGIATRNGILLISKYQHMEHTDDSLTKTI 955
Cdd:COG0841 864 VYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEGMSLREAI 943
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1082435988 956 VAGSLDRLNPILMTALTAALALIPLVLnGDKSGNEIQSPMAVVVLGGLLTSTLLNIYIVPIAYEILQNRRLKK 1028
Cdd:COG0841 944 LEAARLRLRPILMTSLATILGLLPLAL-GTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDRLRRRL 1015
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
1-1029 |
0e+00 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 637.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 1 MLNNIIKFSLNNKLFILLGAVLLIVGGTYTFQKMDVDVFPDLTAPTVVLMTDAHGMAPEEVERLVSFPIETAVNGATDVR 80
Cdd:TIGR00914 1 MIERIISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 81 RVRSASLQGYSFVWVEFEWGTNIFKARQIVSEKMGTLTSSLPVGIIPVLAPQSSLMGEILFVGLQADSTS---------M 151
Cdd:TIGR00914 81 TTRSLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTGLGEIFLYTVEAEEGArkkdggaytL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 152 MELRTLADWIVKPAILATGGVSQVTIIGGDYKQYQILADPVKMNAYGVTLQELKSVGKTLSTNSTGGIIRDYGNEYALRG 231
Cdd:TIGR00914 161 TDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 232 MARTNDLEELGETYVKTRNGRPVVLSDVAEIVIGTPVKMGHASQNAKP----SVILAISKqpniNTLNVTERIEYNLAEI 307
Cdd:TIGR00914 241 PGQVQSMDDIRNIVIATGEGVPIRIRDVARVQIGKELRTGAATENGKEvvlgTVFMLIGE----NSRTVAQAVGDKLETI 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 308 KKTFPADVRMDTkIFRQADFIEASVNNVGIALMEGAIFVIIILFIFLASFRTTIISVIAIPLSLFGTLIVLYLLGMNINT 387
Cdd:TIGR00914 317 NKTLPEGVEIVT-TYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANL 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 388 MTLGGmcIAIGSLVDDAIIDVENVYKRL--RQNHIKPKEERESVVSVIYKASVEIRASILNATFIIIVAFIPLFFLSGME 465
Cdd:TIGR00914 396 MSLGA--LDFGLIVDGAVVIVENAHRRLaeAQHHHGRQLTLKERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVE 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 466 GRMLKPLGVAYIVSLFMSLVVAMTITPLLCRMMLSRDnyldKKTKDNWLTQKLSTLYERSLLWVLTNKKIVIYPTIALLL 545
Cdd:TIGR00914 474 GKMFHPMAFTVVLALAGAMILSLTFVPAAVALFIRGK----VAEKENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIV 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 546 VAGVLFVTMGRSFLPEFNEGSLTISAVTKPGVTLDESDRLGNLIETELLLLPEVTSTARRTGRGELDEHSLSTNSAEIDV 625
Cdd:TIGR00914 550 LVVWIASRVGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGTAEIATDPMPPNASDTYI 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 626 ------NFTLGKRGREEFMAEVREKLGAVPGLAFTVGQPLGHRIDHMLSGTRANIAIKLFGTDLSQMFMIANQIKGSIIG 699
Cdd:TIGR00914 630 ilkpesQWPEGKKTKEDLIEEIQEATVRIPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKG 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 700 IDGLVDVAVEQQTETPQLQVRAKRSMLAQYGISIEDFNEFIELAFAGEKLSEIYEGQRSFDLVLKLNKSYTENIEQVKSA 779
Cdd:TIGR00914 710 VPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQL 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 780 LIDTQNGK-----KVPLEEVAEIVSVGGPNSISRENVQRKIVVSANVAGRDLNGVVGEIKANIESQINLPQGYRVEYGGQ 854
Cdd:TIGR00914 790 PIPLPLSEdarkqFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQ 869
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 855 FESAKSASRTLLITSILAICVIFLLLYSEFKNVSLSAIVLVNLPLALIGGVFAVWITSGIISIPSIIGFITLFGIATRNG 934
Cdd:TIGR00914 870 FEQLQSATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNG 949
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 935 ILLISKYQHMEHTDDSLTKTIVAGSLDRLNPILMTALTAALALIPLVLnGDKSGNEIQSPMAVVVLGGLLTSTLLNIYIV 1014
Cdd:TIGR00914 950 LVMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAI-ATGTGAEVQRPLATVVIGGIITATLLTLFVL 1028
|
1050
....*....|....*
gi 1082435988 1015 PIAYEILQNRRLKKE 1029
Cdd:TIGR00914 1029 PALYRLVHRRRHKGR 1043
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
21-1021 |
8.50e-140 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 445.23 E-value: 8.50e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 21 VLLIVGGTYTFQKMDVDVFPDLTAPTVVLMTDAHGMAPEEVERLVSFPIETAVNGATDVRRVRSASLQGYSFVWVEFEWG 100
Cdd:NF033617 16 LLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSLGYSTITLQFRLG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 101 TNIFKARQIVSEKMGTLTSSLPVGI--IPVLAPQSSLMGEILFVGLQADSTSMMELRTLADWIVKPAILATGGVSQVTII 178
Cdd:NF033617 96 TDLDVALSEVQAAINAAQSLLPSEApdPPVYRKANSADTPIMYIGLTSEEMPRGQLTDYAERVLAPKLSQINGVGSVDVS 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 179 GGDYKQYQILADPVKMNAYGVTLQELKSVGKTLSTNSTGGIIRDYGNEYALRGMARTNDLEELGETYVK-TRNGRPVVLS 257
Cdd:NF033617 176 GGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYEDLVIKyADNGAPVRLG 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 258 DVAEIVIGTPVKMGHASQNAKPSVILAISKQPNINTLNVTERIEYNLAEIKKTFPADVRMDTkIFRQADFIEASVNNVGI 337
Cdd:NF033617 256 DVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIKVNV-LYDRTRFIRASIDEVES 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 338 ALMEGAIFVIIILFIFLASFRTTIISVIAIPLSLFGTLIVLYLLGMNINTMTLGGMCIAIGSLVDDAIIDVENVYKrlrq 417
Cdd:NF033617 335 TLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDDAIVVVENIHR---- 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 418 nHIkpkEERESVVSVIYKASVEIRASILNATFIIIVAFIPLFFLSGMEGRMLKPLGVAYIVSLFMSLVVAMTITPLLC-R 496
Cdd:NF033617 411 -HI---EEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLTPMMCsR 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 497 MMLSRDNYLDKKTKDNWLTQKLSTLYERSLLWVLTNKKIVIYPTIALLLVAGVLFVTMGRSFLPEFNEGSLTISAVTKPG 576
Cdd:NF033617 487 LLKANEKPGRFARAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVIFGMIQAPQS 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 577 VTLDESDRLGNLIETELLLLPEVTSTARRTGRGELDehslSTNSAEIDVNFT-LGKRGR--EEFMAEVREKLGAVPGLAF 653
Cdd:NF033617 567 ISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGGNP----GDNTGFGIINLKpWDERDVsaQEIIDRLRPKLAKVPGMDL 642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 654 TVGQplghrIDHMLSGTRANIAIKLF---GTDLSQMFMIANQIKGSIIGIDGLVDVAVEQQTETPQLQVRAKRSMLAQYG 730
Cdd:NF033617 643 FLFP-----LQDLPGGAGSSLPQYQVtltPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDIDRDKAARLG 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 731 ISIEDFNEFIELAFAGEKLSEIYEGQRSFDLVLKLNKSYTENIEQVKSALIDTQNGKKVPLEEVAEIVSVGGPNSISREN 810
Cdd:NF033617 718 ISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLSTLAKIEERAAPLSLNHFN 797
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 811 VQRKIVVSANVAGRDLNGVVGEIKANIESQInLPQGYRVEYGGQFESAKSASRTLLITSILAICVIFLLLYSEFKNVSLS 890
Cdd:NF033617 798 QFNSATLSFNLAPGVSLGEAIEALDQAAKEL-LPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAIQYESFVDP 876
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 891 AIVLVNLPLALIGGVFAVWITSGIISIPSIIGFITLFGIATRNGILLIS---KYQHmeHTDDSLTKTIVAGSLDRLNPIL 967
Cdd:NF033617 877 LTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEfanELQR--HQGLSRREAIYQAAALRLRPIL 954
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....
gi 1082435988 968 MTALTAALALIPLVLNGDkSGNEIQSPMAVVVLGGLLTSTLLNIYIVPIAYEIL 1021
Cdd:NF033617 955 MTTLAMLLGAIPLMLSTG-AGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLL 1007
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
7-1029 |
3.09e-85 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 297.41 E-value: 3.09e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 7 KFSLNNKLFILLGAVLLIVGGTYTFQKMDVDVFPDLTAPTVVLMTDAHGMAPEEVERLVSFPIETAVNGATDVRRVRS-A 85
Cdd:TIGR00915 3 KFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSSsS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 86 SLQGYSFVWVEFEWGTNIFKARQIVSEKMGTLTSSLPVGI----IPVLAPQSSLmgeILFVGLQADSTSM--MELRTLAD 159
Cdd:TIGR00915 83 DSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVqrqgVRVEKASSNF---LMVIGLVSDDGSMtkEDLSDYAA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 160 WIVKPAILATGGVSQVTIIGGDYKQyQILADPVKMNAYGVTLQELKSVGKT----LSTNSTGGIIRDYGNEY--ALRGMA 233
Cdd:TIGR00915 160 SNMVDPLSRLEGVGDVQLFGSQYAM-RIWLDPAKLNSYQLTPADVISAISAqnaqISAGQLGGLPAVPGQQLnaTIIAQT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 234 RTNDLEELGETYVKT-RNGRPVVLSDVAEIVIGTPVKMGHASQNAKPSVILAISKQPNINTLNVTERIEYNLAEIKKTFP 312
Cdd:TIGR00915 239 RLQTPEQFENILLKVnTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFP 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 313 ADVRMDTKiFRQADFIEASVNNVGIALMEGAIFVIIILFIFLASFRTTIISVIAIPLSLFGTLIVLYLLGMNINTMTLGG 392
Cdd:TIGR00915 319 QGMKYVYP-YDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFA 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 393 MCIAIGSLVDDAIIDVENVYKRLRQNHIKPKEEREsvvsviyKASVEIRASILNATFIIIVAFIPLFFLSGMEGRMLKPL 472
Cdd:TIGR00915 398 MVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATR-------KSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQF 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 473 GVAYIVSLFMSLVVAMTITPLLCRMMLSRDNYLDKKTKD----NWLTQKLSTL---YERSLLWVLTNKK--IVIYptiAL 543
Cdd:TIGR00915 471 SITIVSAMALSVLVALILTPALCATMLKPIEKGEHHEKKggffGWFNRMFDSSthgYENGVGKILRRRGryLLVY---VL 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 544 LLVAGV-LFVTMGRSFLPEFNEGSLTISAVTKPGVTLDESDRLGNLIETELLL--LPEVTSTARRT-----GRGE----- 610
Cdd:TIGR00915 548 LVGGMVfLFVRLPTSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAkeKANVESVFTVNgfsfaGRGQnmgma 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 611 ------LDEHSLSTNSAeidvnFTLGKRGREEFMaEVREKLG--AVPGLAFTVGQPLG---HRIDHMlsgtraniaiklf 679
Cdd:TIGR00915 628 firlkdWEERTGKENSV-----FAIAGRATGHFM-QIKDAMViaFVPPAILELGNATGfdfFLQDRA------------- 688
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 680 GTDLSQMFMIANQIKGSIIGIDGLVDVAVEQQTETPQLQVRAKRSMLAQYGISIEDFNEFIELAFAGEKLSE-IYEGqRS 758
Cdd:TIGR00915 689 GLGHEALLQARNQLLGLAAQNPALTRVRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDfIDRG-RV 767
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 759 FDLVLKLNKSYTENIEQVKSALIDTQNGKKVPLEEVAEIVSVGGPNSISRENVQRKIVVSANVAGRDLNGVVGEIKANIE 838
Cdd:TIGR00915 768 KRVYVQAEEDARMSPEDINKWYVRNASGEMVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIA 847
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 839 SQinLPQGYRVEYGGQ-FESAKSASRTLLITSiLAICVIFLLLYSEFKNVSLSAIVLVNLPLALIGGVFAVWITSGIISI 917
Cdd:TIGR00915 848 QK--LPPGFGFSWTGMsYEERLSGSQAPALYA-LSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDV 924
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 918 PSIIGFITLFGIATRNGILLISKYQHMEHTDDSLTKTIVAGSLDRLNPILMTALTAALALIPLVL-NGDKSGNeiQSPMA 996
Cdd:TIGR00915 925 YFQVGLLTTIGLSAKNAILIVEFAKELMAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAIsTGAGSGS--QHAIG 1002
|
1050 1060 1070
....*....|....*....|....*....|...
gi 1082435988 997 VVVLGGLLTSTLLNIYIVPIAYeILQNRRLKKE 1029
Cdd:TIGR00915 1003 TGVFGGMVTATVLAIFFVPLFY-VVVRRLFKRK 1034
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
14-1031 |
1.15e-65 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 240.40 E-value: 1.15e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 14 LFI------LLGAVLLIVGGTYTFQKMDVDVFPDLTAPTVVLMTDAHGMAPEEVERLVSFPIETAVNGATDVRRVRSASL 87
Cdd:PRK10614 6 LFIyrpvatILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 88 QGYSFVWVEFEWGTNIFKARQIVSEKMGTLTSSLPVGII---------PVLAPqsslmgeILFVGLQADSTSMMELRTLA 158
Cdd:PRK10614 86 LGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPsrptyrkanPSDAP-------IMILTLTSDTYSQGQLYDFA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 159 DWIVKPAILATGGVSQVTIIGGDYKQYQILADPVKMNAYGVTLQELKSVGKTLSTNSTGGIIRDYGNEYALRgmarTNDL 238
Cdd:PRK10614 159 STQLAQTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQ----TNDE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 239 EELGETY----VKTRNGRPVVLSDVAEIVIGTPVKMGHASQNAKPSVILAISKQPNINTLNVTERIEYNLAEIKKTFPAD 314
Cdd:PRK10614 235 LKTAAEYqpliIHYNNGAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPAA 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 315 VRMDTKIFRQADfIEASVNNVGIALMEGAIFVIIILFIFLASFRTTIISVIAIPLSLFGTLIVLYLLGMNINTMTLGGMC 394
Cdd:PRK10614 315 IDLQIAQDRSPT-IRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALT 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 395 IAIGSLVDDAIIDVENVYKRLrQNHIKPKEeresvvsVIYKASVEIRASILNATFIIIVAFIPLFFLSGMEGRMLKPLGV 474
Cdd:PRK10614 394 IATGFVVDDAIVVLENISRHL-EAGMKPLQ-------AALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAV 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 475 AYIVSLFMSLVVAMTITPLLCRMML--SRDNYLDKKTKDNWLTQKLSTLYERSLLWVLTNKKIVIYPTIALLLVAGVLFV 552
Cdd:PRK10614 466 TLSVAIGISLLVSLTLTPMMCAWLLksSKPREQKRLRGFGRMLVALQQGYGRSLKWVLNHTRWVGVVLLGTIALNVWLYI 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 553 TMGRSFLPEFNEGSLTisavtkPGVTLDES-------DRLGNLIETeLLLLPEVTSTARRTGRGEldehslsTNSAEIDV 625
Cdd:PRK10614 546 SIPKTFFPEQDTGRLM------GFIQADQSisfqamrGKLQDFMKI-IRDDPAVDNVTGFTGGSR-------VNSGMMFI 611
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 626 NFT-LGKRGR--EEFMAEVREKLGAVPG--LAFTVGQplghriDHMLSGTRANIAIK--LFGTDLSQMFMIANQIKGSII 698
Cdd:PRK10614 612 TLKpLSERSEtaQQVIDRLRVKLAKEPGanLFLMAVQ------DIRVGGRQSNASYQytLLSDDLAALREWEPKIRKALA 685
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 699 GIDGLVDVAVEQQTETPQLQVRAKRSMLAQYGISIEDFNEFIELAFAGEKLSEIYEGQRSFDLVLKLNKSYTENIEQVKS 778
Cdd:PRK10614 686 ALPELADVNSDQQDKGAEMALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEK 765
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 779 ALIDTQNGKKVPLEEVAEIVSVGGPNSISRENVQRKIVVSANVA-GRDLNGVVGEIKANIeSQINLPQGYRVEYGGQFES 857
Cdd:PRK10614 766 MFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPtGKSLSDASAAIERAM-TQLGVPSTVRGSFAGTAQV 844
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 858 AKSASRTLLITSILAICVIFLLLYSEFKNVSLSAIVLVNLPLALIGGVFAVWITSGIISIPSIIGFITLFGIATRNGILL 937
Cdd:PRK10614 845 FQETMNSQLILILAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMM 924
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 938 ISKYQHMEHTDD-SLTKTIVAGSLDRLNPILMTALTAALALIPLVL-NGDksGNEIQSPMAVVVLGGLLTSTLLNIYIVP 1015
Cdd:PRK10614 925 VDFALEAQRNGNlTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLsGGD--GAELRQPLGITIVGGLVMSQLLTLYTTP 1002
|
1050
....*....|....*.
gi 1082435988 1016 IAYEILQNRRLKKEQQ 1031
Cdd:PRK10614 1003 VVYLFFDRLRLRFSRK 1018
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
7-1021 |
1.87e-65 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 239.75 E-value: 1.87e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 7 KFSLNNKLFILLGAVLLIVGGTYTFQKMDVDVFPDLTAPTVVLMTDAHGMAPEEVERLVSFPIETAVNGATDVRRVRSAS 86
Cdd:PRK09577 3 RFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 87 LQGYSFVWVEFEWGTNIFKARQIVSEKMGTLTSSLPVGI----IPVLAPQSSLMgeiLFVGLQADSTSM--MELRTLADW 160
Cdd:PRK09577 83 SAGQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVrrdgIQVEKAADNIQ---LIVSLTSDDGRLtgVELGEYASA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 161 IVKPAILATGGVSQVTIIGGDYKQyQILADPVKMNAYGVTLQELKSVGKTLSTNSTGGIIRDYG-NEYALRGMARTNDL- 238
Cdd:PRK09577 160 NVLQALRRVEGVGKVQFWGAEYAM-RIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAvPDSAPIAATVFADAp 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 239 ----EELGETYVKTR-NGRPVVLSDVAEIVIGTPVKMGHASQNAKPSVILAISKQPNINTLNVTERIEYNLAEIKKTFPA 313
Cdd:PRK09577 239 lktpEDFGAIALRARaDGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPP 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 314 DVRMDTKiFRQADFIEASVNNVGIALMEGAIFVIIILFIFLASFRTTIISVIAIPLSLFGTLIVLYLLGMNINTMTLGGM 393
Cdd:PRK09577 319 GVKYQIP-YETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGM 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 394 CIAIGSLVDDAIIDVENVYKRLRQNHIKPKEeresvvsVIYKASVEIRASILNATFIIIVAFIPLFFLSGMEGRMLKPLG 473
Cdd:PRK09577 398 VLAIGILVDDAIVVVENVERLMVEEGLSPYD-------ATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFA 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 474 VAYIVSLFMSLVVAMTITPLLCRMMLS--RDNYLDKKTKDNWL-----------TQKLSTLYERSLLWvltnkkIVIYPt 540
Cdd:PRK09577 471 LSLAVSIGFSAFLALSLTPALCATLLKpvDGDHHEKRGFFGWFnrfvarstqryATRVGAILKRPLRW------LVVYG- 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 541 iALLLVAGVLFVTMGRSFLPEFNEGSLTISAVTKPGVTLDESDRlgNLIETElLLLPEVTSTARRTGRGELDEHSLSTNS 620
Cdd:PRK09577 544 -ALTAAAALLFTRLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQ--SVREVE-SYLRRHEPVAYTFALGGFNLYGEGPNG 619
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 621 AEIDVNFTLGKRGREE------FMAEVREKLGAVPGLA-FTVGQP----LGHR--IDHMLSgTRANIAIKLFGTDLSQmf 687
Cdd:PRK09577 620 GMIFVTLKDWKERKAArdhvqaIVARINERFAGTPNTTvFAMNSPalpdLGSTsgFDFRLQ-DRGGLGYAAFVAAREQ-- 696
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 688 MIANQIKGSIigidgLVDVAVEQQTETPQLQVRAKRSMLAQYGISIEDFNEFIELAFAGEKLSEIYEGQRSFDLVLKLNK 767
Cdd:PRK09577 697 LLAEGAKDPA-----LTDLMFAGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADG 771
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 768 SYTENIEQVKSALIDTQNGKKVPLEEVAEIVSVGGPNSISRENVQRKIVVSANVA-GRDlngvVGEIKANIESQI-NLPQ 845
Cdd:PRK09577 772 RHRLDPDDVKKLRVRNAQGEMVPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAApGHS----SGEAMAAIERIAaTLPA 847
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 846 GYRVEYGGQ-FESAKSASRTLLITSiLAICVIFLLLYSEFKNVSLSAIVLVNLPLALIGGVFAVWITSGIISIPSIIGFI 924
Cdd:PRK09577 848 GIGYAWSGQsFEERLSGAQAPMLFA-LSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLI 926
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 925 TLFGIATRNGILLISKYQHMEHTDDSLTKTIVAGSLDRLNPILMTALTAALALIPLVL-NGDKSGneIQSPMAVVVLGGL 1003
Cdd:PRK09577 927 ATIGLSAKNAILIVEVAKDLVAQRMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFaSGAASG--AQIAIGTGVLGGV 1004
|
1050
....*....|....*...
gi 1082435988 1004 LTSTLLNIYIVPIAYEIL 1021
Cdd:PRK09577 1005 ITATVLAVFLVPLFFVVV 1022
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
20-1032 |
1.44e-62 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 231.26 E-value: 1.44e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 20 AVLLIVGGTYTFQKMDVDVFPDLTAPTVVLMTDAHGMAPEEVERLVSFPIETAVNGATDVRRVRSASLQGYSFVWVEFEW 99
Cdd:PRK09579 18 SLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRQNFSIISIYARI 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 100 GTNIFKARQIVSEKMGTLTSSLPVGI-IPVLAPQSSLMGEILFVGLQADSTSMMELRTLADWIVKPAILATGGVSQVTII 178
Cdd:PRK09579 98 GADSDRLFTELLAKANEVKNQLPQDAeDPVLSKEAADASALMYISFYSEEMSNPQITDYLSRVIQPKLATLPGMAEAEIL 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 179 GGDYKQYQILADPVKMNAYGVTLQELKSVGKTLSTNSTGGIIRdygNEYALRGMARTNDL---EELGETYVKTRNGRPVV 255
Cdd:PRK09579 178 GNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVK---GEYVVTSINASTELksaEAFAAIPVKTSGDSRVL 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 256 LSDVAEIVIGTPVKMGHASQNAKPSVILAISKQPNINTLNVTERIEYNLAEIKKTFPADVRMDTKiFRQADFIEASVNNV 335
Cdd:PRK09579 255 LGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLKVSIA-YDATLFIQASIDEV 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 336 GIALMEGAIFVIIILFIFLASFRTTIISVIAIPLSLFGTLIVLYLLGMNINTMTLGGMCIAIGSLVDDAIIDVENVYKrl 415
Cdd:PRK09579 334 VKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIGLVVDDAIVVVENIHR-- 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 416 rqnHIkpkEERESVVSVIYKASVEIRASILNATFIIIVAFIPLFFLSGMEGRMLKPLGVAYIVSLFMSLVVAMTITPLLC 495
Cdd:PRK09579 412 ---HI---EEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGIVALTLSPMMC 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 496 RMMLSRD-NYLDKKTKDNWLTQKLSTLYERSLLWVLTNKKIVIYPTIALLLVAGVLFVTMGRSFLPEFNEGSLTISAVTK 574
Cdd:PRK09579 486 ALLLRHEeNPSGLAHRLDRLFERLKQRYQRALHGTLNTRPVVLVFAVIVLALIPVLLKFTQSELAPEEDQGIIFMMSSSP 565
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 575 PGVTLDESDRLGNLIETELLLLPEVTSTARRTGrgeldehslsTNSAEIDVNFTLGK------RGREEFMAEVREKLGAV 648
Cdd:PRK09579 566 QPANLDYLNAYTDEFTPIFKSFPEYYSSFQING----------FNGVQSGIGGFLLKpwnereRTQMELLPLVQAKLEEI 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 649 PGLaftvgQPLGHRIDHmLSGTRANIAIKLF---GTDLSQMFMIANQIKGSIIGIDGLVDVAVEQQTETPQLQVRAKRSM 725
Cdd:PRK09579 636 PGL-----QIFGFNLPS-LPGTGEGLPFQFVintANDYESLLQVAQRVKQRAQESGKFAFLDIDLAFDKPEVVVDIDRAK 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 726 LAQYGISIEDFNEFIELAFAGEKLSEIYEGQRSFDLVLKLNKSYTENIEQVKSALIDTQNGKKVPLEEVAEIVSVGGPns 805
Cdd:PRK09579 710 AAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYYVKNEQGQLLPLSTLITLSDRARP-- 787
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 806 isRENVQRKIVVSANVAGRDLNGvVGEIKANIE--SQINLPQGYRVEYGG---QFESAKSAsrtLLITSILAICVIFLLL 880
Cdd:PRK09579 788 --RQLNQFQQLNSAIISGFPIVS-MGEAIETVQqiAREEAPEGFAFDYAGasrQYVQEGSA---LWVTFGLALAIIFLVL 861
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 881 YSEFKNVSLSAIVLVNLPLALIGGVFAVWITSGIISIPSIIGFITLFGIATRNGILLISKYQHMEHTDD-SLTKTIVAGS 959
Cdd:PRK09579 862 AAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLRHEQGlSRREAIEEAA 941
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1082435988 960 LDRLNPILMTALTAALALIPLVLnGDKSGNEIQSPMAVVVLGGLLTSTLLNIYIVPIAYEILQNRRLKKEQQI 1032
Cdd:PRK09579 942 AIRLRPVLMTTAAMVFGMVPLIL-ATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIYTLLAKPDAAPGVAQ 1013
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
7-1032 |
5.65e-62 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 229.41 E-value: 5.65e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 7 KFSLNNKLFILLGAVLLIVGGTYTFQKMDVDVFPDLTAPTVVLMTDAHGMAPEEVERLVSFPIETAVNGATDVRRVRSAS 86
Cdd:PRK15127 3 NFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 87 -LQGYSFVWVEFEWGTNIFKARQIVSEKMGTLTSSLPVGI----IPVLAPQSSLMgeiLFVGLQADSTSMMElRTLADWI 161
Cdd:PRK15127 83 dSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVqqqgVSVEKSSSSFL---MVVGVINTDGTMTQ-EDISDYV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 162 ---VKPAILATGGVSQVTIIGGDYKQyQILADPVKMNAYGVT----LQELKSVGKTLSTNSTGGIIRDYGNEYALRGMAR 234
Cdd:PRK15127 159 aanMKDPISRTSGVGDVQLFGSQYAM-RIWMNPNELNKFQLTpvdvINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQ 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 235 T--NDLEELGETYVKT-RNGRPVVLSDVAEIVIGTPVKMGHASQNAKPSVILAISKQPNINTLNVTERIEYNLAEIKKTF 311
Cdd:PRK15127 238 TrlTSTEEFGKILLKVnQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFF 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 312 PADVRMdTKIFRQADFIEASVNNVGIALMEGAIFVIIILFIFLASFRTTIISVIAIPLSLFGTLIVLYLLGMNINTMTLG 391
Cdd:PRK15127 318 PSGLKI-VYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMF 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 392 GMCIAIGSLVDDAIIDVENVYKRLRQNHIKPKEERESVVSVIYKASVEIrASILNATfiiivaFIPLFFLSGMEGRMLKP 471
Cdd:PRK15127 397 GMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGI-AMVLSAV------FVPMAFFGGSTGAIYRQ 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 472 LGVAYIVSLFMSLVVAMTITPLLCRMMLSR----DNYLDKKTKDNWLTQ---KLSTLYERSLLWVL--TNKKIVIYptia 542
Cdd:PRK15127 470 FSITIVSAMALSVLVALILTPALCATMLKPiakgDHGEGKKGFFGWFNRmfeKSTHHYTDSVGNILrsTGRYLVLY---- 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 543 LLLVAG--VLFVTMGRSFLPEFNEGSLTISAVTKPGVTLDESDRlgnlietellLLPEVTSTArrtgrgeLDEHSLSTNS 620
Cdd:PRK15127 546 LIIVVGmaYLFVRLPSSFLPDEDQGVFLTMVQLPAGATQERTQK----------VLNEVTDYY-------LTKEKNNVES 608
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 621 AEIDVNFTLGKRGREEFMAEVR-----EKLGA---VPGLAFTVGQPLGHRIDHMLS----------GTRANIAIKLF--- 679
Cdd:PRK15127 609 VFAVNGFGFAGRGQNTGIAFVSlkdwaDRPGEenkVEAITMRATRAFSQIKDAMVFafnlpaivelGTATGFDFELIdqa 688
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 680 GTDLSQMFMIANQIKGSIIG-IDGLVDVAVEQQTETPQLQVRAKRSMLAQYGISIEDFNEFIELAFAGEKLSEIYEGQRS 758
Cdd:PRK15127 689 GLGHEKLTQARNQLLGEAAKhPDMLVGVRPNGLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRV 768
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 759 FDLVLKLNKSYTENIEQVKSALIDTQNGKKVPLEEVAEIVSVGGPNSISRENVQRKIVVSANVAGRDLNGVVGEIKANIE 838
Cdd:PRK15127 769 KKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEELA 848
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 839 SQinLPQGYRVEYGG-QFESAKSASRTLLITSIlAICVIFLLLYSEFKNVSLSAIVLVNLPLALIGGVFAVWITSGIISI 917
Cdd:PRK15127 849 SK--LPTGVGYDWTGmSYQERLSGNQAPALYAI-SLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDV 925
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 918 PSIIGFITLFGIATRNGILLISKYQH-MEHTDDSLTKTIVAGSLDRLNPILMTALTAALALIPLVLNgDKSGNEIQSPMA 996
Cdd:PRK15127 926 YFQVGLLTTIGLSAKNAILIVEFAKDlMDKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVIS-SGAGSGAQNAVG 1004
|
1050 1060 1070
....*....|....*....|....*....|....*.
gi 1082435988 997 VVVLGGLLTSTLLNIYIVPIAYEILQNRRLKKEQQI 1032
Cdd:PRK15127 1005 TGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKNEDI 1040
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
7-1025 |
1.76e-61 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 227.79 E-value: 1.76e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 7 KFSLNNKLFILLGAVLLIVGGTYTFQKMDVDVFPDLTAPTVVLMTDAHGMAPEEVERLVSFPIETAVNGATDVRRVRS-A 85
Cdd:PRK10555 3 NFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSqS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 86 SLQGYSFVWVEFEWGTNIFKARQIVSEKMGTLTSSLPVGI----IPVLAPQSSLMGEILFVglqaDSTSMMELRTLADWI 161
Cdd:PRK10555 83 SGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVqnqgVTVRKTGDTNILTIAFV----STDGSMDKQDIADYV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 162 ---VKPAILATGGVSQVTIIGGDYKQyQILADPVKMNAYGVTLQE----LKSVGKTLSTNSTGGIirDYGNEYALRGMAR 234
Cdd:PRK10555 159 asnIQDPLSRVNGVGDIDAYGSQYSM-RIWLDPAKLNSFQMTTKDvtdaIESQNAQIAVGQLGGT--PSVDKQALNATIN 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 235 TNDLEELGE-----TYVKTRNGRPVVLSDVAEIVIGTPvKMGHASQ-NAKPSVILAISKQPNINTLNVTERIEYNLAEIK 308
Cdd:PRK10555 236 AQSLLQTPEqfrdiTLRVNQDGSEVTLGDVATVELGAE-KYDYLSRfNGKPASGLGVKLASGANEMATAKLVLNRLDELA 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 309 KTFPADvrMDTKI-FRQADFIEASVNNVGIALMEGAIFVIIILFIFLASFRTTIISVIAIPLSLFGTLIVLYLLGMNINT 387
Cdd:PRK10555 315 QYFPHG--LEYKVaYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINT 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 388 MTLGGMCIAIGSLVDDAIIDVENVYKRLRQNHIKPKEERESVVSVIYKASVEIrASILNATfiiivaFIPLFFLSGMEGR 467
Cdd:PRK10555 393 LTMFAMVLAIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGI-AMVLSAV------FVPMAFFGGTTGA 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 468 MLKPLGVAYIVSLFMSLVVAMTITPLLCRMML---SRDNYLDKKTKDNWLTQKL---STLYERSLLWVLTN--KKIVIYp 539
Cdd:PRK10555 466 IYRQFSITIVSAMVLSVLVAMILTPALCATLLkplKKGEHHGQKGFFGWFNRMFnrnAERYEKGVAKILHRslRWILIY- 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 540 tIALLLVAGVLFVTMGRSFLPEFNEGSLTISAVTKPGVTLDESDRLGNLIETELLLLPE--VTSTARRTGRG-------- 609
Cdd:PRK10555 545 -VLLLGGMVFLFLRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEKdnVMSVFATVGSGpggngqnv 623
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 610 --------ELDEHSLSTNSAeidvnFTLGKRGREEF--MAEVR---EKLGAVPGLAFTVGQPLGHRiDHMLSGTRANIAI 676
Cdd:PRK10555 624 armfirlkDWDERDSKTGTS-----FAIIERATKAFnkIKEARviaSSPPAISGLGSSAGFDMELQ-DHAGAGHDALMAA 697
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 677 KlfgtdlSQMFMIANQIKgsiigidGLVDVAVEQQTETPQLQVRAKRSMLAQYGISIEDFNEFIELAFAGEKLSEIYEGQ 756
Cdd:PRK10555 698 R------NQLLALAAKNP-------ELTRVRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRG 764
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 757 RSFDLVLKLNKSYTENIEQVKSALIDTQNGKKVPLEEVAEIVSVGGPNSISRENVQRKIVVSANVAGRDLNGVVGEIKAN 836
Cdd:PRK10555 765 RVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMES 844
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 837 IESQinLPQGYRVEYGG---QFESAKSASRTLLITSILaicVIFLLLYSEFKNVSLSAIVLVNLPLALIGGVFAVWITSG 913
Cdd:PRK10555 845 LVKQ--LPNGFGLEWTAmsyQERLSGAQAPALYAISLL---VVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGL 919
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 914 IISIPSIIGFITLFGIATRNGILLISKYQHMEHTDDSLTKTIVAGSLDRLNPILMTALTAALALIPLVL-NGDKSGNeiQ 992
Cdd:PRK10555 920 ENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATsTGAGSGS--Q 997
|
1050 1060 1070
....*....|....*....|....*....|...
gi 1082435988 993 SPMAVVVLGGLLTSTLLNIYIVPIAYeILQNRR 1025
Cdd:PRK10555 998 HAVGTGVMGGMISATILAIFFVPLFF-VLVRRR 1029
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
13-997 |
1.05e-60 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 225.76 E-value: 1.05e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 13 KLFIL------LGAVLLIVGGTYTFQKMDVDVFPDLTAPTVVLMTDAHGMAPEEVERLVSFPIETAVNGATDVRRVRSAS 86
Cdd:PRK10503 14 RLFILrpvattLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQS 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 87 LQGYSFVWVEFEWGTNIFKARQIVSEKMGTLTSSLPVGI--IPVLAPQSSLMGEILFVGLQADSTSMMELRTLADWIVKP 164
Cdd:PRK10503 94 SGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLpnPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQ 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 165 AILATGGVSQVTIIGGdykqyQILADPVKMNA-----YGVTLQELKSVGKTLSTNSTGGIIRDYGNEYALRGMARTNDLE 239
Cdd:PRK10503 174 KISQVSGVGLVTLSGG-----QRPAVRVKLNAqaiaaLGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSANDQMQSAE 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 240 ELGETYVKTRNGRPVVLSDVAEIVIGTPVKMGHASQNAKPSVILAISKQPNINTLNVTERIEYNLAEIKKTFPADVRMDT 319
Cdd:PRK10503 249 EYRQLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVKVTV 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 320 KIFRQADfIEASVNNVGIALMEGAIFVIIILFIFLASFRTTIISVIAIPLSLFGTLIVLYLLGMNINTMTLGGMCIAIGS 399
Cdd:PRK10503 329 LSDRTTN-IRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGF 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 400 LVDDAIIDVENVYKRLrqnhikpkEERESVVSVIYKASVEIRASILNATFIIIVAFIPLFFLSGMEGRMLKPLGVAYIVS 479
Cdd:PRK10503 408 VVDDAIVVIENISRYI--------EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 480 LFMSLVVAMTITPLLCRMMLSRDNyldkKTKDNWLTQKLSTLYERSLLW-------VLTNKKIVIYPTIALLLVAGVLFV 552
Cdd:PRK10503 480 ILISAVVSLTLTPMMCARMLSQES----LRKQNRFSRASERMFDRVIAAygrglakVLNHPWLTLSVALSTLLLTVLLWI 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 553 TMGRSFLPEFNEGSLTISAVTKPGVTLDESDRLGNLIETELLLLPEVTSTARRTGrgeLDEHSLSTNSAEIDVNFT-LGK 631
Cdd:PRK10503 556 FIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVG---VDGTNPSLNSARLQINLKpLDE 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 632 RGR--EEFMAEVREKLGAVPGLAFTVgQPLGH-RIDHMLSgtRANIAIKLFGTDLSQMFMIANQIKGSIIGIDGLVDVAV 708
Cdd:PRK10503 633 RDDrvQKVIARLQTAVAKVPGVDLYL-QPTQDlTIDTQVS--RTQYQFTLQATSLDALSTWVPKLMEKLQQLPQLSDVSS 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 709 EQQTETPQLQVRAKRSMLAQYGISIEDFNEFIELAFAGEKLSEIYEGQRSFDLVLKLNKSYTENIEQVKSALIDTQNGKK 788
Cdd:PRK10503 710 DWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGV 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 789 VPLEEVAEIVSVGGPNSISRENVQRKIVVSANVA-GRDLNGVVGEIKaNIESQINLPQGYRVEYGGQ---FESAKSASRT 864
Cdd:PRK10503 790 VPLSSIATIEQRFGPLSINHLDQFPSTTISFNVPdGYSLGDAVQAIM-DTEKTLNLPADITTQFQGStlaFQSALGSTVW 868
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 865 LLITSILAICVIFLLLYSEFKNvslSAIVLVNLPLALIGGVFAVWITSGIISIPSIIGFITLFGIATRNGILLI------ 938
Cdd:PRK10503 869 LIVAAVVAMYIVLGVLYESFIH---PITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIdfalaa 945
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*....
gi 1082435988 939 SKYQHMEHTDdsltkTIVAGSLDRLNPILMTALTAALALIPLVLNgDKSGNEIQSPMAV 997
Cdd:PRK10503 946 EREQGMSPRD-----AIYQACLLRFRPILMTTLAALLGALPLMLS-TGVGAELRRPLGI 998
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
356-498 |
4.34e-08 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 57.18 E-value: 4.34e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 356 SFRTTIISVIAIPLSLFGTLIVLYLLGMNINTMTLGGMCIAIGSLVDDAIidveNVYKRLRQNhikpKEERESVVSVIYK 435
Cdd:COG1033 628 SLRLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTI----HFLSRYREE----RRKGGDLEEAIRR 699
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1082435988 436 ASVEIRASILNATFIIIVAFIPLFFlSGMegRMLKPLGVAYIVSLFMSLVVAMTITPLLCRMM 498
Cdd:COG1033 700 ALRTTGKAILFTSLTLAAGFGVLLF-SSF--PPLADFGLLLALGLLVALLAALLLLPALLLLL 759
|
|
| actII |
TIGR00833 |
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ... |
258-555 |
3.13e-07 |
|
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 129913 [Multi-domain] Cd Length: 910 Bit Score: 54.59 E-value: 3.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 258 DVAEIV--IGTPVKMGHASQNAKPSVILAISKQPNINTLNVTERIEYNLAEIKKTFPAD---VRMDTKIFRQADFIEASV 332
Cdd:TIGR00833 93 HVISVVdfWGPPEAAEGLRSDDGKATIIIVNLAGEKGQKEAQEAINAVRRIVEQTNAPDgltVHVTGPLATIADILESGD 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 333 NNVGIALMEGAIFVIIILFIFLASFRTTIISVIAIPLSLFGTLIVLYLLGMN----INTMTLGGMC-IAIGSLVDDAIId 407
Cdd:TIGR00833 173 KDMNRITATTGIIVLIILLLVYRSPITMLVPLVSVGFSVVVAQGIVSLLGIPgligVNAQTTVLLTaLVIGAGTDYAVF- 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 408 VENVYKRLRQNHIKPKEeresvvsVIYKASVEIRASILNATFIIIVAFIPLFFlSGMEgrMLKPLGVAYIVSLFMSLVVA 487
Cdd:TIGR00833 252 LTGRYHEERRKGESLEE-------AAAEALRGTGKAILGSALTVAVAFLALSL-ARLP--SFKTLGVSCAVGVLVALLNA 321
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1082435988 488 MTITPLLCrMMLSRDNYLDKKTKDnwltqKLSTLYERSllwvltNKKIVIYPTIALLLVAGVLFVTMG 555
Cdd:TIGR00833 322 VTLTPALL-TLEGREGLMKPGRKS-----KIRFIWRRL------GTAVVRRPWPILVTTLIISGVSLL 377
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
680-1029 |
1.56e-04 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 45.75 E-value: 1.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 680 GTDLSQMfmIANQIKGSIIGIDGLVDVAVEQQTEtPQLQVRAKRSMLAQYGISIEDFNEFIELAFAGEKLSEIYEGQRSF 759
Cdd:pfam00873 150 QTDLRDY--ADTNIKPQLSRVPGVGDVQLFGGSE-YAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQA 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 760 dLVLKLNKSYTenIEQVKSALIDTQNGKKVPLEEVAEiVSVGGPNS--ISRENVQRKIVVSANVA-GRDLNGVVGEIKAN 836
Cdd:pfam00873 227 -LIRAQGQLQS--AEDFEKIIVKNQDGSPVRLRDVAT-VELGSELYrgFATFNGKPAVGLGVQKLpGANAIETADAVRAK 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 837 IES-QINLPQGYRVEYG---GQF--ESAKSASRTLLITSILAICVIFLLLysefKNVSLSAIVLVNLPLALIGGvFAVwi 910
Cdd:pfam00873 303 LAElKPTFPQGVEIVVVydtTPFirASIEEVVKTLLEAIVLVILVMFLFL----QNWRATLIPAIAIPLSLLGT-FAV-- 375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 911 tsgIISIPSIIGFITLFGIATRNGILLISK-------YQHMEHTDDSLTKTIVAGSLDRLNPILMTALTAALALIPLVLN 983
Cdd:pfam00873 376 ---MKAFGFSINTLTLGGLVLAIGLVVDDAivvveniERVLEENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFL 452
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 1082435988 984 GDKSGnEIQSPMAVVVLGGLLTSTLLNIYIVPIAYEI-LQNRRLKKE 1029
Cdd:pfam00873 453 GGLTG-RIFRQFAITIVLAILLSVLVALTLTPALCATlLKPRREPKH 498
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
819-982 |
2.12e-03 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 42.15 E-value: 2.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 819 ANVAGRDLNGVVGEIKANIESQINlPQGYRVEYGGQF----ESAKSASRTLLITSILAICVIFLLLYSEFKNVSLSAIVL 894
Cdd:COG1033 558 KDLDSEEIKALVEEVRAFLAENFP-PDGVEVTLTGSAvlfaAINESVIESQIRSLLLALLLIFLLLLLAFRSLRLGLISL 636
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 895 VnlPLAL-IGGVFAVWITSGIISIPSIIGFITL-FGIATRNGILLISKYQHMEHTDDSLTKTIVAGSLDRLNPILMTALT 972
Cdd:COG1033 637 I--PNLLpILLTFGLMGLLGIPLNIATAVVASIaLGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAILFTSLT 714
|
170
....*....|
gi 1082435988 973 AALALIPLVL 982
Cdd:COG1033 715 LAAGFGVLLF 724
|
|
| PLN02413 |
PLN02413 |
choline-phosphate cytidylyltransferase |
204-252 |
2.52e-03 |
|
choline-phosphate cytidylyltransferase
Pssm-ID: 215229 Cd Length: 294 Bit Score: 41.08 E-value: 2.52e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1082435988 204 LKSVGKTLSTNSTGG---------IIRDYgNEYALRGMARTNDLEELGETYVKTRNGR 252
Cdd:PLN02413 138 VKKIGKFKETKRTDGistsdiimrIVKDY-NQYVMRNLARGYSRKDLGVSYVKEKRLR 194
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
326-544 |
3.86e-03 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 41.36 E-value: 3.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 326 DFIEASVNNVGIALMEGAIFVIIILFIFlasFRTTIISVIAIPLSLFGTLIVL---YLLG--MNINTMTLGGMCIAIGSl 400
Cdd:TIGR00921 186 DIEREFGKDMGTTMAISGILVVLVLLLD---FKRWWRPLLPLVIILFGVAWVLgimGWLGipLYATTLLAVPMLIGVGI- 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 401 vdDAIIDVENVYKRLRQnhiKPKEERESVVSVIYKASveirASILNATFIIIVAFIPLfFLSGMegRMLKPLGVAYIVSL 480
Cdd:TIGR00921 262 --DYGIQTLNRYEEERD---IGRAKGEAIVTAVRRTG----RAVLIALLTTSAGFAAL-ALSEF--PMVSEFGLGLVAGL 329
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1082435988 481 FMSLVVAMTITPLLcrmMLSRDNYLDKKTKDNWLTQKLSTLYERSlLWVLTnKKIVIYPTIALL 544
Cdd:TIGR00921 330 ITAYLLTLLVLPAL---LQSIDIGREKVKKEIIAIGGKSSEIEEE-LSKVL-SITVRHPVPALV 388
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
361-577 |
4.41e-03 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 41.24 E-value: 4.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 361 IISVIAIPLSLFGTLIVLYLLGMNINTMTLGGMCIAIGSLVDDAIIdvenVYKRLRqnhikpkEERESVVSVIYKASVEI 440
Cdd:PRK14726 398 VIAVIALIVNVVLIIAVLSLLGATLTLPGIAGIVLTIGMAVDSNVL----IYERIR-------EEEKTGHSLIQALDRGF 466
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 441 R---ASILNATFIIIVAFIPLFFL-SGMegrmLKPLGVAYIVSLFMSLVVAMTITPLLCRMMLSRdnyldkkTKDNWLTQ 516
Cdd:PRK14726 467 SralATIVDANVTILIAAVILFFLgSGA----VRGFAVTLAVGILTTVFTAFTLTRSLVAVWLRR-------RRPKHLPK 535
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1082435988 517 KLST-LYERSLLWVLTNKKIVIYPTIALLLVAGVLFVTMGRSFLPEFNEGSLtISAVTKPGV 577
Cdd:PRK14726 536 GVRTgLFEGANIRFMGIRRYVFTLSAALSLASLVLFATVGLNLGIDFTGGSL-IEVRAKQGN 596
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
350-553 |
5.79e-03 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 40.61 E-value: 5.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 350 LFIFLASFRTTIISVIAIPLSLFGTLIVLYLLGMNIN--TMTLGGMCIAIGslVDDAIIdvenVYKRLRQNHIKPKEERE 427
Cdd:COG1033 235 LFLFFRSLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSplTILVPPLLLAIG--IDYGIH----LLNRYREERRKGLDKRE 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 428 SVVSVIykasVEIRASILNATFIIIVAFIPLFFlsgMEGRMLKPLGVAYIVSLFMSLVVAMTITPLLcrmmLSrdnYLDK 507
Cdd:COG1033 309 ALREAL----RKLGPPVLLTSLTTAIGFLSLLF---SDIPPIRDFGIVAAIGVLLAFLTSLTLLPAL----LS---LLPR 374
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1082435988 508 KTKDNWLTQKLSTLyERSLLWV---LTNKKIVIYPTIALLLVAGVLFVT 553
Cdd:COG1033 375 PKPKTRRLKKPPEL-GRLLAKLarfVLRRPKVILVVALVLAVVSLYGIS 422
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
325-508 |
8.08e-03 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 39.58 E-value: 8.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 325 ADFIEASVNNVGIALMEGAIFVIIILFIFLASFRTTIISVIAIPLSLF----GTLIVLYLLGMNINTMTLG-GMCIAIGS 399
Cdd:pfam03176 134 ADLRDAGDRDLGLIEAVTLVVIFIILLIVYRSVVAALLPLLTVGLSLGaaqgLVAILAHILGIGLSTFALNlLVVLLIAV 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082435988 400 LVDDAIIDVENvYKRLRQNHIKPKEeresvvsVIYKASVEIRASILNATFIIIVAFIPLFFLSgmeGRMLKPLGVAYIVS 479
Cdd:pfam03176 214 GTDYALFLVSR-YREELRAGEDREE-------AVIRAVRGTGKVVTAAGLTVAIAMLALSFAR---LPVFAQVGPTIAIG 282
|
170 180
....*....|....*....|....*....
gi 1082435988 480 LFMSLVVAMTITPLLCrMMLSRDNYLDKK 508
Cdd:pfam03176 283 VLVDVLAALTLLPALL-ALLGRWGLWPPK 310
|
|
| |
