|
Name |
Accession |
Description |
Interval |
E-value |
| SAICAR_synt_Ade5 |
cd01416 |
Ade5_like 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; ... |
7-258 |
0e+00 |
|
Ade5_like 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Eukaryotic group of SAICAR synthetases represented by the Drosophila melanogaster, N-terminal, SAICAR synthetase domain of bifunctional Ade5. The Ade5 gene product (CAIR-SAICARs) catalyzes the sixth and seventh steps of the de novo biosynthesis of purine nucleotides (also reported as seventh and eighth steps). SAICAR synthetase converts 5-aminoimidazole-4-carboxyribonucleotide (CAIR), ATP, and L-aspartate into 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR), ADP, and phosphate.
:
Pssm-ID: 133471 Cd Length: 252 Bit Score: 521.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 7 LKLGKKLNEGKTKEVYELPEHYGCVLMKSKDQITAGDAVRKDHMEGKASISNKTTSCVFKLLQEAGIKTAFVRKCGDTAF 86
Cdd:cd01416 1 LKLGKKLIEGKTKIVYELPDQPGLVLIQSKDRITAGDGARKDEIEGKAAISNKTTSNVFELLQEAGIKTHFVKQCSPTAF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 87 IATHCEMIPIEWVCRRIATGSFLKRNPGVKEGYKFLPPKVETFFKDDANHDPQWSEEQLISAKLSCGGLVIGQAEVDIMT 166
Cdd:cd01416 81 IARKCEMIPIEWVCRRIATGSFLKRNPGVKEGYRFSPPKLEFFYKDDANHDPQWSEEQLLEAKLNCGGLKIGKKEVDIMT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 167 HSTAAIFEILEKAWMSQECTLVDMKIEFGVDVTKKEIVLADVIDNDSWRLWPAGDKSQQKDKQTYRDLKEVTAEALQMVK 246
Cdd:cd01416 161 KSTIAIFEILEKAWATQDCTLVDMKIEFGVDVTTGEILLADVIDNDSWRLWPSGDKRLMKDKQVYRNLKEVTDEALQEVK 240
|
250
....*....|..
gi 1050394675 247 RNFEWVADRVEL 258
Cdd:cd01416 241 KNYEWVADKLEL 252
|
|
| purE |
TIGR01162 |
phosphoribosylaminoimidazole carboxylase, PurE protein; Phosphoribosylaminoimidazole ... |
268-421 |
2.86e-53 |
|
phosphoribosylaminoimidazole carboxylase, PurE protein; Phosphoribosylaminoimidazole carboxylase is a fusion protein in plants and fungi, but consists of two non-interacting proteins in bacteria, PurK and PurE. This model represents PurK, an N5-CAIR mutase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
:
Pssm-ID: 273474 Cd Length: 156 Bit Score: 174.73 E-value: 2.86e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 268 VVVLMGSISDLAHCEKIKKSCANYGLPCELRVTSAHKGPDETLRIKSEYEGDGmATVFIAVAGRSNGLGPVMSGNSAYPV 347
Cdd:TIGR01162 1 VGIIMGSDSDLPTMKKAADILEEFGIPYELRVVSAHRTPELMLEYAKTAEERG-IKVIIAGAGGAAHLPGMVAALTPLPV 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1050394675 348 INCP-PLTADWAAQDVWSSLRMPSGLGCSTVLSPEAAAQFAAQIF--GLNNHLVWSKLRSCTLNTWISLKQADMKLR 421
Cdd:TIGR01162 80 IGVPvPSKALSGLDSLLSIVQMPSGVPVATVAIGNAGNAALLAAQilGIKDPELAEKLKEYRENQKEEVLKKNKKLE 156
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SAICAR_synt_Ade5 |
cd01416 |
Ade5_like 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; ... |
7-258 |
0e+00 |
|
Ade5_like 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Eukaryotic group of SAICAR synthetases represented by the Drosophila melanogaster, N-terminal, SAICAR synthetase domain of bifunctional Ade5. The Ade5 gene product (CAIR-SAICARs) catalyzes the sixth and seventh steps of the de novo biosynthesis of purine nucleotides (also reported as seventh and eighth steps). SAICAR synthetase converts 5-aminoimidazole-4-carboxyribonucleotide (CAIR), ATP, and L-aspartate into 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR), ADP, and phosphate.
Pssm-ID: 133471 Cd Length: 252 Bit Score: 521.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 7 LKLGKKLNEGKTKEVYELPEHYGCVLMKSKDQITAGDAVRKDHMEGKASISNKTTSCVFKLLQEAGIKTAFVRKCGDTAF 86
Cdd:cd01416 1 LKLGKKLIEGKTKIVYELPDQPGLVLIQSKDRITAGDGARKDEIEGKAAISNKTTSNVFELLQEAGIKTHFVKQCSPTAF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 87 IATHCEMIPIEWVCRRIATGSFLKRNPGVKEGYKFLPPKVETFFKDDANHDPQWSEEQLISAKLSCGGLVIGQAEVDIMT 166
Cdd:cd01416 81 IARKCEMIPIEWVCRRIATGSFLKRNPGVKEGYRFSPPKLEFFYKDDANHDPQWSEEQLLEAKLNCGGLKIGKKEVDIMT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 167 HSTAAIFEILEKAWMSQECTLVDMKIEFGVDVTKKEIVLADVIDNDSWRLWPAGDKSQQKDKQTYRDLKEVTAEALQMVK 246
Cdd:cd01416 161 KSTIAIFEILEKAWATQDCTLVDMKIEFGVDVTTGEILLADVIDNDSWRLWPSGDKRLMKDKQVYRNLKEVTDEALQEVK 240
|
250
....*....|..
gi 1050394675 247 RNFEWVADRVEL 258
Cdd:cd01416 241 KNYEWVADKLEL 252
|
|
| SAICAR_synt |
pfam01259 |
SAICAR synthetase; Also known as Phosphoribosylaminoimidazole-succinocarboxamide synthase. |
12-240 |
6.84e-93 |
|
SAICAR synthetase; Also known as Phosphoribosylaminoimidazole-succinocarboxamide synthase.
Pssm-ID: 460140 Cd Length: 228 Bit Score: 279.25 E-value: 6.84e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 12 KLNEGKTKEVYELPEHyGCVLMKSKDQITAGDAVRKDHMEGKASISNKTTSCVFKLLQEAGIKTAFVRKCGDTAFIATHC 91
Cdd:pfam01259 1 LLYEGKVKDVYETDDP-DTLLVVAKDRISAFDGVKKGTIPGKGAVNNQISAFWFELLEIAGIPTHFIKSLSGREMLVKKV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 92 EMIPIEWVCRRIATGSFLKRNPGVKEGYKFLPPKVETFFKDDANHDPQWSEEQLISAKLscgglvIGQAEVDIMTHSTAA 171
Cdd:pfam01259 80 KIIPLEVVVRNYAAGSLGKRLPGLKEGTKLPEPIFEPSTKADALGDPNINEEHIVALGL------ATEEEAEEIRELALK 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1050394675 172 IFEILEKAWMSQECTLVDMKIEFGVDVTkKEIVLADVIDNDSWRLWPAGD--KSQQK-DKQTYRD----LKEVTAE 240
Cdd:pfam01259 154 INEILKEYAAERGIILVDTKLEFGLDSD-GEIVLADEITPDSSRFWDADTyeKSQESlDKDRFRDdlgdVEEAYQE 228
|
|
| PurC |
COG0152 |
Phosphoribosylaminoimidazole-succinocarboxamide synthase [Nucleotide transport and metabolism]; ... |
7-245 |
1.85e-65 |
|
Phosphoribosylaminoimidazole-succinocarboxamide synthase [Nucleotide transport and metabolism]; Phosphoribosylaminoimidazole-succinocarboxamide synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439922 Cd Length: 245 Bit Score: 209.55 E-value: 1.85e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 7 LKLGKKLNEGKTKEVYELPEHYgcVLMKSKDQITAGDAVRKDHMEGKASISNKTTSCVFKLLQEAGIKTAFVRKCGDTAF 86
Cdd:COG0152 1 MPKLELLYEGKVKDVYATDDDT--LLMVFKDRISAFDGVKPDPIPGKGEVLNQISAFWFELLEDIGIPTHFIETLSGREM 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 87 IATHCEMIPIEWVCRRIATGSFLKR-------NPGVKEGYKFLPPKVETFFKDDANHDPQWSEEQLISAKLscgglvIGQ 159
Cdd:COG0152 79 LVKKLEMIPVEVVVRNYAAGSLWKRyqagialPLGLEEGTKLPEPIFEPSTKADEGHDPNISEEHIVALGL------ATE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 160 AEVDIMTHSTAAIFEILEKAWMSQECTLVDMKIEFGVDvTKKEIVLADVIDNDSWRLWPAGDKsQQKDKQTYRD-LKEVT 238
Cdd:COG0152 153 EEAEELRELALKINERLSELAAERGIILVDTKLEFGRD-ADGEIVLADEITPDSSRLWDADTY-ESLDKDRFRDwLGGNT 230
|
....*..
gi 1050394675 239 AEALQMV 245
Cdd:COG0152 231 SEAYIEV 237
|
|
| PRK09362 |
PRK09362 |
phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed |
10-260 |
9.89e-62 |
|
phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed
Pssm-ID: 181800 Cd Length: 238 Bit Score: 199.56 E-value: 9.89e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 10 GKKLNEGKTKEVYELPEHyGCVLMKSKDQITAGDAVRKDHMEGKASISNKTTSCVFKLLQEAGIKTAFVRKCGDTAFIAT 89
Cdd:PRK09362 4 KELLYEGKAKIVYSTDDP-DLLIVEFKDDATAFNGEKKEQIDGKGVLNNQISSFIFKKLEEAGIPTHFIEKLSDREQLVK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 90 HCEMIPIEWVCRRIATGSFLKRNpGVKEGYKFLPPKVETFFKDDANHDPQWSEEQLISAKLscgglvIGQAEVDIMTHST 169
Cdd:PRK09362 83 KVEIIPLEVVVRNVAAGSLVKRL-GIEEGTVLPPPIVEFYYKNDALGDPMINEDHILALGW------ATPEELAEIKELA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 170 AAIFEILEKAWMSQECTLVDMKIEFGVDvTKKEIVLADVIDNDSWRLWpagDKSQQK--DKQTYR-DLKEVTaEAlqmvk 246
Cdd:PRK09362 156 LKINDVLKGLFAGAGIRLVDFKLEFGRD-KDGEIVLADEISPDTCRLW---DKETNEklDKDRFRrDLGGVI-EA----- 225
|
250
....*....|....
gi 1050394675 247 rnFEWVADRVELLL 260
Cdd:PRK09362 226 --YEEVLKRLGELL 237
|
|
| purE |
TIGR01162 |
phosphoribosylaminoimidazole carboxylase, PurE protein; Phosphoribosylaminoimidazole ... |
268-421 |
2.86e-53 |
|
phosphoribosylaminoimidazole carboxylase, PurE protein; Phosphoribosylaminoimidazole carboxylase is a fusion protein in plants and fungi, but consists of two non-interacting proteins in bacteria, PurK and PurE. This model represents PurK, an N5-CAIR mutase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273474 Cd Length: 156 Bit Score: 174.73 E-value: 2.86e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 268 VVVLMGSISDLAHCEKIKKSCANYGLPCELRVTSAHKGPDETLRIKSEYEGDGmATVFIAVAGRSNGLGPVMSGNSAYPV 347
Cdd:TIGR01162 1 VGIIMGSDSDLPTMKKAADILEEFGIPYELRVVSAHRTPELMLEYAKTAEERG-IKVIIAGAGGAAHLPGMVAALTPLPV 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1050394675 348 INCP-PLTADWAAQDVWSSLRMPSGLGCSTVLSPEAAAQFAAQIF--GLNNHLVWSKLRSCTLNTWISLKQADMKLR 421
Cdd:TIGR01162 80 IGVPvPSKALSGLDSLLSIVQMPSGVPVATVAIGNAGNAALLAAQilGIKDPELAEKLKEYRENQKEEVLKKNKKLE 156
|
|
| AIRC |
pfam00731 |
AIR carboxylase; Members of this family catalyze the decarboxylation of 1-(5-phosphoribosyl) ... |
268-378 |
1.42e-44 |
|
AIR carboxylase; Members of this family catalyze the decarboxylation of 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR). This family catalyze the sixth step of de novo purine biosynthesis. Some members of this family contain two copies of this domain.
Pssm-ID: 459917 Cd Length: 147 Bit Score: 151.75 E-value: 1.42e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 268 VVVLMGSISDLAHCEKIKKSCANYGLPCELRVTSAHKGPDETLRIKSEYEGDGmATVFIAVAGRSNGLGPVMSGNSAYPV 347
Cdd:pfam00731 1 VGIIMGSDSDLPVMKKAAKILKEFGIPYEVRVVSAHRTPERLLEYAKEAEERG-LKVIIAGAGGAAHLPGMVAALTTLPV 79
|
90 100 110
....*....|....*....|....*....|..
gi 1050394675 348 INCPPLTADWAAQD-VWSSLRMPSGLGCSTVL 378
Cdd:pfam00731 80 IGVPVKSSALDGLDsLLSIVQMPSGVPVATVA 111
|
|
| AIRC |
smart01001 |
AIR carboxylase; Members of this family catalyse the decarboxylation of 1-(5-phosphoribosyl) ... |
266-403 |
1.32e-39 |
|
AIR carboxylase; Members of this family catalyse the decarboxylation of 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR). This family catalyse the sixth step of de novo purine biosynthesis. Some members of this family contain two copies of this domain.
Pssm-ID: 214965 Cd Length: 152 Bit Score: 138.82 E-value: 1.32e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 266 GRVVVLMGSISDLAHCEKIKKSCANYGLPCELRVTSAHKGPDETLRIKSEYEGDGmATVFIAVAGRSNGLGPVMSGNSAY 345
Cdd:smart01001 1 PLVGIIMGSTSDLPVMEEAAKTLEEFGIPYEVGVASAHRTPDRLFEYAKEAEDRG-IKVIIAGAGGAAHLPGVVAALTTL 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1050394675 346 PVINCPPLTADWAAQD-VWSSLRMPSGLGCSTVL----SPEAAAQFAAQIFGLNNHLVWSKLR 403
Cdd:smart01001 80 PVIGVPVSSGYLGGLDsLLSIVQMPSGIPVATVAigidGAFNAALLAAQILALNDPELAAKLA 142
|
|
| PurE |
COG0041 |
Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; ... |
267-330 |
7.15e-10 |
|
Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439811 Cd Length: 161 Bit Score: 57.38 E-value: 7.15e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1050394675 267 RVVVLMGSISDLAHCEKIKKSCANYGLPCELRVTSAHKGPDETLRIKSEYEGDGMAtVFIAVAG 330
Cdd:COG0041 2 KVGIIMGSDSDWPTMKKAAKILDEFGIPYEVRVVSAHRTPDRLFEYAKTAEERGLK-VIIAGAG 64
|
|
| PLN02948 |
PLN02948 |
phosphoribosylaminoimidazole carboxylase |
267-377 |
9.64e-07 |
|
phosphoribosylaminoimidazole carboxylase
Pssm-ID: 178534 [Multi-domain] Cd Length: 577 Bit Score: 50.83 E-value: 9.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 267 RVVVLMGSISDLAHCEKIKKSCANYGLPCELRVTSAHKGPDETLRIKSEYEGDGMaTVFIAVAGRSNGLGPVMSGNSAYP 346
Cdd:PLN02948 412 LVGIIMGSDSDLPTMKDAAEILDSFGVPYEVTIVSAHRTPERMFSYARSAHSRGL-QVIIAGAGGAAHLPGMVASMTPLP 490
|
90 100 110
....*....|....*....|....*....|..
gi 1050394675 347 VINCPPLTADWAAQD-VWSSLRMPSGLGCSTV 377
Cdd:PLN02948 491 VIGVPVKTSHLDGLDsLLSIVQMPRGVPVATV 522
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SAICAR_synt_Ade5 |
cd01416 |
Ade5_like 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; ... |
7-258 |
0e+00 |
|
Ade5_like 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Eukaryotic group of SAICAR synthetases represented by the Drosophila melanogaster, N-terminal, SAICAR synthetase domain of bifunctional Ade5. The Ade5 gene product (CAIR-SAICARs) catalyzes the sixth and seventh steps of the de novo biosynthesis of purine nucleotides (also reported as seventh and eighth steps). SAICAR synthetase converts 5-aminoimidazole-4-carboxyribonucleotide (CAIR), ATP, and L-aspartate into 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR), ADP, and phosphate.
Pssm-ID: 133471 Cd Length: 252 Bit Score: 521.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 7 LKLGKKLNEGKTKEVYELPEHYGCVLMKSKDQITAGDAVRKDHMEGKASISNKTTSCVFKLLQEAGIKTAFVRKCGDTAF 86
Cdd:cd01416 1 LKLGKKLIEGKTKIVYELPDQPGLVLIQSKDRITAGDGARKDEIEGKAAISNKTTSNVFELLQEAGIKTHFVKQCSPTAF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 87 IATHCEMIPIEWVCRRIATGSFLKRNPGVKEGYKFLPPKVETFFKDDANHDPQWSEEQLISAKLSCGGLVIGQAEVDIMT 166
Cdd:cd01416 81 IARKCEMIPIEWVCRRIATGSFLKRNPGVKEGYRFSPPKLEFFYKDDANHDPQWSEEQLLEAKLNCGGLKIGKKEVDIMT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 167 HSTAAIFEILEKAWMSQECTLVDMKIEFGVDVTKKEIVLADVIDNDSWRLWPAGDKSQQKDKQTYRDLKEVTAEALQMVK 246
Cdd:cd01416 161 KSTIAIFEILEKAWATQDCTLVDMKIEFGVDVTTGEILLADVIDNDSWRLWPSGDKRLMKDKQVYRNLKEVTDEALQEVK 240
|
250
....*....|..
gi 1050394675 247 RNFEWVADRVEL 258
Cdd:cd01416 241 KNYEWVADKLEL 252
|
|
| SAICAR_synt |
cd00476 |
5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; SAICAR synthetase ... |
12-257 |
1.04e-95 |
|
5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; SAICAR synthetase (the PurC gene product) catalyzes the seventh step of the de novo biosynthesis of purine nucleotides (also reported as eighth step). It converts 5-aminoimidazole-4-carboxyribonucleotide (CAIR), ATP, and L-aspartate into 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR), ADP, and phosphate.
Pssm-ID: 133468 Cd Length: 230 Bit Score: 286.67 E-value: 1.04e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 12 KLNEGKTKEVYELPEHYgcVLMKSKDQITAGDAVRKDHMEGKASISNKTTSCVFKLLQEAGIKTAFVRKCGDTAFIATHC 91
Cdd:cd00476 1 TLYRGKTKIVYETKDGV--LLLEFKDDISAGDGARRNFLDEKGDITAKLTLFIFKYLSEAGIPTHFVERLGPRTLLVDKL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 92 EMIPIEWVCRRIATGSFLKRNPGVKEGYKFLPPKVETFFKDDANHDPQWSEEQLISAKlscgglVIGQAEVDIMTHSTAA 171
Cdd:cd00476 79 K*IPLEVVVRNRATGSFVKRYGGFKEGREFPPPLVEFFYKDDAEHDPIVSEDQLERLG------FIGKVDVER*KELAVK 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 172 IFEILEKAWMSQECTLVDMKIEFGVDVtKKEIVLADVIDNDSWRLWPAGDKSQQKDKQTYRDlkevtaeALQMVKRNFEW 251
Cdd:cd00476 153 INTVLKKLFSPAGLELWDFKLEFGLDE-EGEIVLGDEISPDSSRLWRKGGEPYDKDLFRRRA-------SLGQIIEKYEE 224
|
....*.
gi 1050394675 252 VADRVE 257
Cdd:cd00476 225 VAELVR 230
|
|
| SAICAR_synt |
pfam01259 |
SAICAR synthetase; Also known as Phosphoribosylaminoimidazole-succinocarboxamide synthase. |
12-240 |
6.84e-93 |
|
SAICAR synthetase; Also known as Phosphoribosylaminoimidazole-succinocarboxamide synthase.
Pssm-ID: 460140 Cd Length: 228 Bit Score: 279.25 E-value: 6.84e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 12 KLNEGKTKEVYELPEHyGCVLMKSKDQITAGDAVRKDHMEGKASISNKTTSCVFKLLQEAGIKTAFVRKCGDTAFIATHC 91
Cdd:pfam01259 1 LLYEGKVKDVYETDDP-DTLLVVAKDRISAFDGVKKGTIPGKGAVNNQISAFWFELLEIAGIPTHFIKSLSGREMLVKKV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 92 EMIPIEWVCRRIATGSFLKRNPGVKEGYKFLPPKVETFFKDDANHDPQWSEEQLISAKLscgglvIGQAEVDIMTHSTAA 171
Cdd:pfam01259 80 KIIPLEVVVRNYAAGSLGKRLPGLKEGTKLPEPIFEPSTKADALGDPNINEEHIVALGL------ATEEEAEEIRELALK 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1050394675 172 IFEILEKAWMSQECTLVDMKIEFGVDVTkKEIVLADVIDNDSWRLWPAGD--KSQQK-DKQTYRD----LKEVTAE 240
Cdd:pfam01259 154 INEILKEYAAERGIILVDTKLEFGLDSD-GEIVLADEITPDSSRFWDADTyeKSQESlDKDRFRDdlgdVEEAYQE 228
|
|
| PurC |
COG0152 |
Phosphoribosylaminoimidazole-succinocarboxamide synthase [Nucleotide transport and metabolism]; ... |
7-245 |
1.85e-65 |
|
Phosphoribosylaminoimidazole-succinocarboxamide synthase [Nucleotide transport and metabolism]; Phosphoribosylaminoimidazole-succinocarboxamide synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439922 Cd Length: 245 Bit Score: 209.55 E-value: 1.85e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 7 LKLGKKLNEGKTKEVYELPEHYgcVLMKSKDQITAGDAVRKDHMEGKASISNKTTSCVFKLLQEAGIKTAFVRKCGDTAF 86
Cdd:COG0152 1 MPKLELLYEGKVKDVYATDDDT--LLMVFKDRISAFDGVKPDPIPGKGEVLNQISAFWFELLEDIGIPTHFIETLSGREM 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 87 IATHCEMIPIEWVCRRIATGSFLKR-------NPGVKEGYKFLPPKVETFFKDDANHDPQWSEEQLISAKLscgglvIGQ 159
Cdd:COG0152 79 LVKKLEMIPVEVVVRNYAAGSLWKRyqagialPLGLEEGTKLPEPIFEPSTKADEGHDPNISEEHIVALGL------ATE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 160 AEVDIMTHSTAAIFEILEKAWMSQECTLVDMKIEFGVDvTKKEIVLADVIDNDSWRLWPAGDKsQQKDKQTYRD-LKEVT 238
Cdd:COG0152 153 EEAEELRELALKINERLSELAAERGIILVDTKLEFGRD-ADGEIVLADEITPDSSRLWDADTY-ESLDKDRFRDwLGGNT 230
|
....*..
gi 1050394675 239 AEALQMV 245
Cdd:COG0152 231 SEAYIEV 237
|
|
| PRK09362 |
PRK09362 |
phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed |
10-260 |
9.89e-62 |
|
phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed
Pssm-ID: 181800 Cd Length: 238 Bit Score: 199.56 E-value: 9.89e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 10 GKKLNEGKTKEVYELPEHyGCVLMKSKDQITAGDAVRKDHMEGKASISNKTTSCVFKLLQEAGIKTAFVRKCGDTAFIAT 89
Cdd:PRK09362 4 KELLYEGKAKIVYSTDDP-DLLIVEFKDDATAFNGEKKEQIDGKGVLNNQISSFIFKKLEEAGIPTHFIEKLSDREQLVK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 90 HCEMIPIEWVCRRIATGSFLKRNpGVKEGYKFLPPKVETFFKDDANHDPQWSEEQLISAKLscgglvIGQAEVDIMTHST 169
Cdd:PRK09362 83 KVEIIPLEVVVRNVAAGSLVKRL-GIEEGTVLPPPIVEFYYKNDALGDPMINEDHILALGW------ATPEELAEIKELA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 170 AAIFEILEKAWMSQECTLVDMKIEFGVDvTKKEIVLADVIDNDSWRLWpagDKSQQK--DKQTYR-DLKEVTaEAlqmvk 246
Cdd:PRK09362 156 LKINDVLKGLFAGAGIRLVDFKLEFGRD-KDGEIVLADEISPDTCRLW---DKETNEklDKDRFRrDLGGVI-EA----- 225
|
250
....*....|....
gi 1050394675 247 rnFEWVADRVELLL 260
Cdd:PRK09362 226 --YEEVLKRLGELL 237
|
|
| SAICAR_synt_PurC |
cd01415 |
bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) ... |
12-246 |
4.85e-60 |
|
bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; A subfamily of SAICAR synthetases represented by the Thermotoga maritima (Tm) enzyme and E. coli PurC. SAICAR synthetase catalyzes the seventh step of the de novo biosynthesis of purine nucleotides (also reported as eighth step). It converts 5-aminoimidazole-4-carboxyribonucleotide (CAIR), ATP, and L-aspartate into 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR), ADP, and phosphate.
Pssm-ID: 133470 Cd Length: 230 Bit Score: 194.98 E-value: 4.85e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 12 KLNEGKTKEVYELPEHyGCVLMKSKDQITAGDAVRKDHMEGKASISNKTTSCVFKLLQEAGIKTAFVRKCGDTAFIATHC 91
Cdd:cd01415 1 LLYEGKAKIVYATDDP-DVLIVEFKDDATAFNGKKKDTIEGKGVLNNEISALIFKYLEENGIKTHFIEKLSDREQLVKKV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 92 EMIPIEWVCRRIATGSFLKRNpGVKEGYKFLPPKVETFFKDDANHDPQWSEEQLISAKLscgglvIGQAEVDIMTHSTAA 171
Cdd:cd01415 80 EIIPLEVVVRNIAAGSLVKRL-GIEEGTVLDPPIVEFYYKNDELGDPLINEDHILALGL------ATEEELKEIKELALK 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 172 IFEILEKAWMSQECTLVDMKIEFGVDvTKKEIVLADVIDNDSWRLWpagDKSQQK--DKQTYR----DLKEVTAEALQMV 245
Cdd:cd01415 153 INEVLSEFFAEIGIILVDFKLEFGRD-KDGEIVLADEISPDTCRLW---DKETGEklDKDRFRrdlgDVIEAYEEVLKRL 228
|
.
gi 1050394675 246 K 246
Cdd:cd01415 229 G 229
|
|
| purE |
TIGR01162 |
phosphoribosylaminoimidazole carboxylase, PurE protein; Phosphoribosylaminoimidazole ... |
268-421 |
2.86e-53 |
|
phosphoribosylaminoimidazole carboxylase, PurE protein; Phosphoribosylaminoimidazole carboxylase is a fusion protein in plants and fungi, but consists of two non-interacting proteins in bacteria, PurK and PurE. This model represents PurK, an N5-CAIR mutase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273474 Cd Length: 156 Bit Score: 174.73 E-value: 2.86e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 268 VVVLMGSISDLAHCEKIKKSCANYGLPCELRVTSAHKGPDETLRIKSEYEGDGmATVFIAVAGRSNGLGPVMSGNSAYPV 347
Cdd:TIGR01162 1 VGIIMGSDSDLPTMKKAADILEEFGIPYELRVVSAHRTPELMLEYAKTAEERG-IKVIIAGAGGAAHLPGMVAALTPLPV 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1050394675 348 INCP-PLTADWAAQDVWSSLRMPSGLGCSTVLSPEAAAQFAAQIF--GLNNHLVWSKLRSCTLNTWISLKQADMKLR 421
Cdd:TIGR01162 80 IGVPvPSKALSGLDSLLSIVQMPSGVPVATVAIGNAGNAALLAAQilGIKDPELAEKLKEYRENQKEEVLKKNKKLE 156
|
|
| AIRC |
pfam00731 |
AIR carboxylase; Members of this family catalyze the decarboxylation of 1-(5-phosphoribosyl) ... |
268-378 |
1.42e-44 |
|
AIR carboxylase; Members of this family catalyze the decarboxylation of 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR). This family catalyze the sixth step of de novo purine biosynthesis. Some members of this family contain two copies of this domain.
Pssm-ID: 459917 Cd Length: 147 Bit Score: 151.75 E-value: 1.42e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 268 VVVLMGSISDLAHCEKIKKSCANYGLPCELRVTSAHKGPDETLRIKSEYEGDGmATVFIAVAGRSNGLGPVMSGNSAYPV 347
Cdd:pfam00731 1 VGIIMGSDSDLPVMKKAAKILKEFGIPYEVRVVSAHRTPERLLEYAKEAEERG-LKVIIAGAGGAAHLPGMVAALTTLPV 79
|
90 100 110
....*....|....*....|....*....|..
gi 1050394675 348 INCPPLTADWAAQD-VWSSLRMPSGLGCSTVL 378
Cdd:pfam00731 80 IGVPVKSSALDGLDsLLSIVQMPSGVPVATVA 111
|
|
| AIRC |
smart01001 |
AIR carboxylase; Members of this family catalyse the decarboxylation of 1-(5-phosphoribosyl) ... |
266-403 |
1.32e-39 |
|
AIR carboxylase; Members of this family catalyse the decarboxylation of 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR). This family catalyse the sixth step of de novo purine biosynthesis. Some members of this family contain two copies of this domain.
Pssm-ID: 214965 Cd Length: 152 Bit Score: 138.82 E-value: 1.32e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 266 GRVVVLMGSISDLAHCEKIKKSCANYGLPCELRVTSAHKGPDETLRIKSEYEGDGmATVFIAVAGRSNGLGPVMSGNSAY 345
Cdd:smart01001 1 PLVGIIMGSTSDLPVMEEAAKTLEEFGIPYEVGVASAHRTPDRLFEYAKEAEDRG-IKVIIAGAGGAAHLPGVVAALTTL 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1050394675 346 PVINCPPLTADWAAQD-VWSSLRMPSGLGCSTVL----SPEAAAQFAAQIFGLNNHLVWSKLR 403
Cdd:smart01001 80 PVIGVPVSSGYLGGLDsLLSIVQMPSGIPVATVAigidGAFNAALLAAQILALNDPELAAKLA 142
|
|
| SAICAR_synt_Sc |
cd01414 |
non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; ... |
12-233 |
2.88e-17 |
|
non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Eukaryotic, bacterial, and archaeal group of SAICAR synthetases represented by the Saccharomyces cerevisiae (Sc) enzyme, mostly absent in metazoans. SAICAR synthetase catalyzes the seventh step of the de novo biosynthesis of purine nucleotides (also reported as eighth step). It converts 5-aminoimidazole-4-carboxyribonucleotide (CAIR), ATP, and L-aspartate into 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR), ADP, and phosphate.
Pssm-ID: 133469 [Multi-domain] Cd Length: 279 Bit Score: 81.44 E-value: 2.88e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 12 KLNEGKTKEVYELPEhyGCVLMKSKDQITAGDAVRKDHMEGKASISNKTTSCVFKLLqEAGIKTAFV------------- 78
Cdd:cd01414 1 LIYSGKVRDVYDLGD--GRLLFVATDRISAFDVILPPDIPGKGEVLTQISAFWFELT-EDIIPNHLIstdvedlpeikep 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 79 RKCGDTAFIATHCEMIPIEWVCRRIATGSFLKR------------NPGVKEGYKFLPPKVETFFKDDANHDPQWSEEQLI 146
Cdd:cd01414 78 EDPDGRSMVVKKAKPIPIECIVRGYLTGSGWKEyqkggtvcgiklPEGLREAQKLPEPIFTPSTKAEEGHDENISFEEAV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 147 SaklscgglVIGQAEVDIMTHSTAAIFEILEKAWMSQECTLVDMKIEFGVDVtKKEIVLADVIDN-DSWRLWPAGDKSQQ 225
Cdd:cd01414 158 E--------IIGAELADELRELALALYERAAEYAAKRGLILADTKFEFGLDE-NGEIILIDEVLTpDSSRFWPADSYEPG 228
|
250
....*....|...
gi 1050394675 226 K-----DKQTYRD 233
Cdd:cd01414 229 KeqpsfDKQFVRD 241
|
|
| PurE |
COG0041 |
Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; ... |
267-330 |
7.15e-10 |
|
Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439811 Cd Length: 161 Bit Score: 57.38 E-value: 7.15e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1050394675 267 RVVVLMGSISDLAHCEKIKKSCANYGLPCELRVTSAHKGPDETLRIKSEYEGDGMAtVFIAVAG 330
Cdd:COG0041 2 KVGIIMGSDSDWPTMKKAAKILDEFGIPYEVRVVSAHRTPDRLFEYAKTAEERGLK-VIIAGAG 64
|
|
| PRK12607 |
PRK12607 |
phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional |
16-219 |
6.30e-08 |
|
phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional
Pssm-ID: 183621 [Multi-domain] Cd Length: 313 Bit Score: 53.74 E-value: 6.30e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 16 GKTKEVYELPEhyGCVLMKSKDQITAGDAVrkdhMEG---KASISNKTTSCVFKllQEAGIKTAFVRKCGD-TAFIATHC 91
Cdd:PRK12607 21 GKVRDNYDLPD--GRRVMVATDRISAFDRV----LPAipyKGQVLNQTAAFWFE--ATKDICPNHVLAVPDpNVVVGKRC 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 92 EMIPIEWVCRRIATGSFL------KRN------P-GVKEGYKFLPPKVETFFK-DDANHDPQWSEEQLISaklscGGLVi 157
Cdd:PRK12607 93 EPFPVEMVVRGYLAGSTWrlykagKREmygvtlPdGLRENQKLPEPIITPTTKaEEGGHDEPISPEEILA-----QGLL- 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1050394675 158 GQAEVDIMTHSTAAIFEILEKAWMSQECTLVDMKIEFGVDVTKKeIVLADVIDN-DSWRLWPA 219
Cdd:PRK12607 167 TPEDWDELSKYALALFARGQEMAAERGLILVDTKYEFGKDADGR-IVLIDEIHTpDSSRYWYA 228
|
|
| PLN02948 |
PLN02948 |
phosphoribosylaminoimidazole carboxylase |
267-377 |
9.64e-07 |
|
phosphoribosylaminoimidazole carboxylase
Pssm-ID: 178534 [Multi-domain] Cd Length: 577 Bit Score: 50.83 E-value: 9.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 267 RVVVLMGSISDLAHCEKIKKSCANYGLPCELRVTSAHKGPDETLRIKSEYEGDGMaTVFIAVAGRSNGLGPVMSGNSAYP 346
Cdd:PLN02948 412 LVGIIMGSDSDLPTMKDAAEILDSFGVPYEVTIVSAHRTPERMFSYARSAHSRGL-QVIIAGAGGAAHLPGMVASMTPLP 490
|
90 100 110
....*....|....*....|....*....|..
gi 1050394675 347 VINCPPLTADWAAQD-VWSSLRMPSGLGCSTV 377
Cdd:PLN02948 491 VIGVPVKTSHLDGLDsLLSIVQMPRGVPVATV 522
|
|
| PLN02544 |
PLN02544 |
phosphoribosylaminoimidazole-succinocarboxamide synthase |
2-220 |
1.73e-06 |
|
phosphoribosylaminoimidazole-succinocarboxamide synthase
Pssm-ID: 178159 [Multi-domain] Cd Length: 370 Bit Score: 49.82 E-value: 1.73e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 2 ESYLDLK---LGKKLnEGKTKEVYELPEHygcVLMKSKDQITAGDAVRKdHMEGKASISNKTTSCVFKLLQEAgIKTAFV 78
Cdd:PLN02544 65 ETNLDLTvpgLGSRR-RGKVRDIYDLGDY---LVLVTTDRQSAFDRVLA-SIPFKGQVLNQTSAWWFNNTKHI-TPNALV 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 79 RKCGDTAFIATHCEMIPIEWVCRRIATGS-----FLKRNPGVKE--GYKF---------LPPKVETFFKDDANHDPQWSE 142
Cdd:PLN02544 139 SSPDPNVTIAKKCSVFPVEFVVRGYMTGStstslWTVYNKGVRNycGNDLpdgmvknqkLPANILTPTTKAADHDVPISP 218
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1050394675 143 EQLISAKLscgglvIGQAEVDIMTHSTAAIFEILEKAWMSQECTLVDMKIEFGVDvTKKEIVLADVIDN-DSWRLWPAG 220
Cdd:PLN02544 219 EEIVEEGL------MTQEDFDEVSSKALALFAFGQEVAAEHGLILVDTKYEFGKD-ADGTILLIDEVHTpDSSRYWLAD 290
|
|
| PRK13961 |
PRK13961 |
phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional |
11-233 |
7.26e-06 |
|
phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional
Pssm-ID: 237571 Cd Length: 296 Bit Score: 47.50 E-value: 7.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 11 KKLNEGKTKEVYELPEHYgcVLMKSKDQITAGDAVRKDHMEGKASISNKTTSCVFKLLQ------------EAGIKTAFV 78
Cdd:PRK13961 13 PLLGRGKVRDIYAVDDDR--LLMVATDRISAFDVILPEPIPDKGRVLTQMSNFWFDKLAhivpnhltgidvDDVVPADEA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 79 RKCGDTAFIATHCEMIPIEWVCRRIATGSFLK---RN---------PGVKEGYKFLPP------KVETffkddANHDPQW 140
Cdd:PRK13961 91 DQVLGRAVVVKKLKPLPVECVVRGYLTGSGWKdyqATgtvcgiklpAGLVEASKLPEPiftpatKAEL-----GDHDENI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1050394675 141 SEEQLISAklsCGGLVIGQA-EVDIMTHSTAAifEI-LEKAWMsqectLVDMKIEFGVDvTKKEIVLAD-VIDNDSWRLW 217
Cdd:PRK13961 166 SFEEVVEL---VGAELAAQLrDATLAIYKEAA--DYaATRGII-----IADTKFEFGLD-EDGTLTLMDeVLTPDSSRFW 234
|
250 260
....*....|....*....|.
gi 1050394675 218 PAGD----KSQQK-DKQTYRD 233
Cdd:PRK13961 235 PADSyqpgTSQPSfDKQFVRD 255
|
|
| |
