NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1032282631|gb|OAO96958|]
View 

TMP-C [Arabidopsis thaliana]

Protein Classification

MIP/aquaporin family protein( domain architecture ID 11088534)

MIP (Major Intrinsic Protein)/aquaporin family protein similar to aquaporin that permits osmotically driven movement of water in both directions, and glycerol uptake facilitator protein that mediates glycerol diffusion across the cytoplasmic membrane via a pore-type mechanism

CATH:  1.20.1080.10
Gene Ontology:  GO:0055085|GO:0015267
PubMed:  11473620|8849412|11964478
SCOP:  3000508
TCDB:  1.A.8

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
 45-274 5.52e-101

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


:

Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 294.61  E-value: 5.52e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631  45 ELSSWSFYRAGIAEFIATFLFLYITVLTVMGVKRAPNMCASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFL 124
Cdd:pfam00230   1 ELRSVSFLRAVIAEFLATLLFVFFGVGSALGVKKLVSSLAVSGLLAVALAFGLALATLVYCAGHISGAHLNPAVTLALLV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 125 ARKLSLTRAVFYMIMQCLGAICGAGVVKGFQPtPYQTLGGGANTVAHGYTKGSGLGAEIIGTFVLVYTVFSATDAKRSAR 204
Cdd:pfam00230  81 GRRFSLLRAIFYIVAQLLGAIAGAALLYGVTV-GLQRAGLFANTLAPGVNAGQAFVVEIILTFQLVYCVFATTDDRRNGS 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 205 DSHVpilAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKdhsWDDHWIFWVGPFIGAALAALYH 274
Cdd:pfam00230 160 LGTV---APLAIGFAVFLNHLAGGPYTGASMNPARSFGPAVVLWK---WDDHWVYWVGPFIGAALGALVY 223
 
Name Accession Description Interval E-value
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
 45-274 5.52e-101

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 294.61  E-value: 5.52e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631  45 ELSSWSFYRAGIAEFIATFLFLYITVLTVMGVKRAPNMCASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFL 124
Cdd:pfam00230   1 ELRSVSFLRAVIAEFLATLLFVFFGVGSALGVKKLVSSLAVSGLLAVALAFGLALATLVYCAGHISGAHLNPAVTLALLV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 125 ARKLSLTRAVFYMIMQCLGAICGAGVVKGFQPtPYQTLGGGANTVAHGYTKGSGLGAEIIGTFVLVYTVFSATDAKRSAR 204
Cdd:pfam00230  81 GRRFSLLRAIFYIVAQLLGAIAGAALLYGVTV-GLQRAGLFANTLAPGVNAGQAFVVEIILTFQLVYCVFATTDDRRNGS 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 205 DSHVpilAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKdhsWDDHWIFWVGPFIGAALAALYH 274
Cdd:pfam00230 160 LGTV---APLAIGFAVFLNHLAGGPYTGASMNPARSFGPAVVLWK---WDDHWVYWVGPFIGAALGALVY 223
MIP cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane ...
 53-277 1.85e-81

Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal cytosolic portion followed by six transmembrane helices, which might have arisen through gene duplication. On the basis of sequence similarity and functional characteristics, the superfamily can be subdivided into two major groups: water-selective channels called aquaporins (AQPs) and glycerol uptake facilitators (GlpFs). AQPs are found in all three kingdoms of life, while GlpFs have been characterized only within microorganisms.


Pssm-ID: 238204  Cd Length: 228  Bit Score: 245.24  E-value: 1.85e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631  53 RAGIAEFIATFLFLYITVLTVMGVKRAPNmcASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTR 132
Cdd:cd00333     1 RKYLAEFLGTFLLVFFGCGSVLAVKLAGG--ASGGLLGIALAWGFAIFVLVYAVGHISGGHINPAVTLALAVGGRFPLIR 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 133 AVFYMIMQCLGAICGAGVVKGFQPTPYQTLGGGANTVAH--------GYTKGSGLGAEIIGTFVLVYTVFSATDAKRSAr 204
Cdd:cd00333    79 VIPYIIAQLLGAILGAALLYGLYYGLYLEFLGANNIVAGifgtypspGVSNGNAFFVEFIGTFILVLVVFATTDDPNGP- 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1032282631 205 dsHVPILAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKDHSWDDHWIFWVGPFIGAALAALYHQIV 277
Cdd:cd00333   158 --PPGGLAPLAIGLLVAAIGLAGGPITGASMNPARSLGPALFTGLARHWHYFWVYWVGPLIGAIAGALVYDYV 228
MIP TIGR00861
MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is ...
 57-274 1.05e-71

MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is large and diverse, possessing over 100 members that all form transmembrane channels. These channel proteins function in water, smallcarbohydrate (e.g., glycerol), urea, NH3, CO2 and possibly ion transport by an energy independent mechanism. They are found ubiquitously in bacteria, archaeaand eukaryotes. The MIP family contains two major groups of channels: aquaporins and glycerol facilitators.The known aquaporins cluster loosely together as do the known glycerol facilitators. MIP family proteins are believed to form aqueous pores that selectively allow passive transport of their solute(s) across the membrane with minimal apparent recognition. Aquaporins selectively transport water (but not glycerol) while glycerol facilitators selectively transport glycerol but not water. Some aquaporins can transport NH3 and CO2. Glycerol facilitators function as solute nonspecific channels, and may transport glycerol, dihydroxyacetone, propanediol, urea and other small neutral molecules in physiologically importantprocesses. Some members of the family, including the yeast FPS protein (TC #1.A.8.5.1) and tobacco NtTIPA may transport both water and small solutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273306 [Multi-domain]  Cd Length: 216  Bit Score: 219.86  E-value: 1.05e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631  57 AEFIATFLFLYITVLTVMGVKRApNMCASVGIQ---GIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTRA 133
Cdd:TIGR00861   1 AEFLGTFLLVFFGVGSALGVNVA-GAYGAVGGGqflGVALAFGLAVATLVYCVGGISGAHLNPAVTIALLLGRRFPLKRV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 134 VFYMIMQCLGAICGAGVVKGFQPTPYQTLGGGANTVAHGYTKGSGLGAEIIGTFVLVYTVFSATDaKRSARDSHvpILAP 213
Cdd:TIGR00861  80 PVYIVAQLIGAILGAALLYGLTSGLFPGNLAVNGSASAGVSSGQAFFVEFIGTAILVLVIFATTD-DRNRVPRG--GFAP 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1032282631 214 LPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKdHSWDDHWIFWVGPFIGAALAALYH 274
Cdd:TIGR00861 157 LAIGLLVFLIHLSMGPYTGTGMNPARSLGPALFAGL-AGWGNHWVYWVGPIIGAILGALVY 216
GlpF COG0580
Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) ...
 56-279 8.35e-58

Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) [Carbohydrate transport and metabolism];


Pssm-ID: 440345 [Multi-domain]  Cd Length: 232  Bit Score: 184.95  E-value: 8.35e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631  56 IAEFIATFLFLYITVLTVMGVKRAPnmcASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTRAVF 135
Cdd:COG0580     7 LAEFLGTFILVLLGCGVVAVLAGTK---GGIGWLGIALAWGLAVLAGVYAFGHISGAHLNPAVTLALAVAGRFPWKDVLP 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 136 YMIMQCLGAICGAGVVKG-FQPTPYQTLGGGA-NTV-----AHGYTKGSGLGAEIIGTFVLVYTVFSATDAKRSARDshv 208
Cdd:COG0580    84 YIIAQLLGAFLGAALVYLiYGGHFDATEDGGAkLGVfatspAIGYSLGAAFLTEIIGTFVLVFVILGITDKRAAPGG--- 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1032282631 209 piLAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIY--NKDHS-WDDHWIFWVGPFIGAALAALYHQIVIR 279
Cdd:COG0580   161 --LAPLAIGLLVAAIGLSLGPLTGYAINPARDLGPRLFHalGKGGSdWGYLWVPIVAPILGAALAALLYRALFG 232
PLN00027 PLN00027
aquaporin TIP; Provisional
 43-277 3.82e-34

aquaporin TIP; Provisional


Pssm-ID: 177664  Cd Length: 252  Bit Score: 124.51  E-value: 3.82e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631  43 PGELSSWSFYRAGIAEFIATFLFLYITVLTVMGVKR----APNMCASVGIQGIAWAFGgmIFALVYCTAGISGGHINPAV 118
Cdd:PLN00027   11 PGEASHPDALKAALAEFISTLIFVFAGEGSGMAFNKltdnGSTTPAGLVAAALAHAFA--LFVAVSVGANISGGHVNPAV 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 119 TFGLFLARKLSLTRAVFYMIMQCLGAICGAGVVKgfqptpYQTlgGGANTVAHGYTKGSG----LGAEIIGTFVLVYTVF 194
Cdd:PLN00027   89 TFGAFIGGNITLLRGILYWIAQLLGSVVACLLLK------FST--GGLETSAFSLSSGVGvwnaFVFEIVMTFGLVYTVY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 195 -SATDAKRsardSHVPILAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIynkDHSWDDHWIFWVGPFIGAALAALY 273
Cdd:PLN00027  161 aTAVDPKK----GDLGIIAPIAIGFIVGANILAGGAFDGASMNPAVSFGPAVV---SWTWTNHWVYWAGPLIGGGIAGLV 233


                  ....
gi 1032282631 274 HQIV 277
Cdd:PLN00027  234 YELI 237
 
Name Accession Description Interval E-value
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
 45-274 5.52e-101

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 294.61  E-value: 5.52e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631  45 ELSSWSFYRAGIAEFIATFLFLYITVLTVMGVKRAPNMCASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFL 124
Cdd:pfam00230   1 ELRSVSFLRAVIAEFLATLLFVFFGVGSALGVKKLVSSLAVSGLLAVALAFGLALATLVYCAGHISGAHLNPAVTLALLV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 125 ARKLSLTRAVFYMIMQCLGAICGAGVVKGFQPtPYQTLGGGANTVAHGYTKGSGLGAEIIGTFVLVYTVFSATDAKRSAR 204
Cdd:pfam00230  81 GRRFSLLRAIFYIVAQLLGAIAGAALLYGVTV-GLQRAGLFANTLAPGVNAGQAFVVEIILTFQLVYCVFATTDDRRNGS 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 205 DSHVpilAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKdhsWDDHWIFWVGPFIGAALAALYH 274
Cdd:pfam00230 160 LGTV---APLAIGFAVFLNHLAGGPYTGASMNPARSFGPAVVLWK---WDDHWVYWVGPFIGAALGALVY 223
MIP cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane ...
 53-277 1.85e-81

Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal cytosolic portion followed by six transmembrane helices, which might have arisen through gene duplication. On the basis of sequence similarity and functional characteristics, the superfamily can be subdivided into two major groups: water-selective channels called aquaporins (AQPs) and glycerol uptake facilitators (GlpFs). AQPs are found in all three kingdoms of life, while GlpFs have been characterized only within microorganisms.


Pssm-ID: 238204  Cd Length: 228  Bit Score: 245.24  E-value: 1.85e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631  53 RAGIAEFIATFLFLYITVLTVMGVKRAPNmcASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTR 132
Cdd:cd00333     1 RKYLAEFLGTFLLVFFGCGSVLAVKLAGG--ASGGLLGIALAWGFAIFVLVYAVGHISGGHINPAVTLALAVGGRFPLIR 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 133 AVFYMIMQCLGAICGAGVVKGFQPTPYQTLGGGANTVAH--------GYTKGSGLGAEIIGTFVLVYTVFSATDAKRSAr 204
Cdd:cd00333    79 VIPYIIAQLLGAILGAALLYGLYYGLYLEFLGANNIVAGifgtypspGVSNGNAFFVEFIGTFILVLVVFATTDDPNGP- 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1032282631 205 dsHVPILAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKDHSWDDHWIFWVGPFIGAALAALYHQIV 277
Cdd:cd00333   158 --PPGGLAPLAIGLLVAAIGLAGGPITGASMNPARSLGPALFTGLARHWHYFWVYWVGPLIGAIAGALVYDYV 228
MIP TIGR00861
MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is ...
 57-274 1.05e-71

MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is large and diverse, possessing over 100 members that all form transmembrane channels. These channel proteins function in water, smallcarbohydrate (e.g., glycerol), urea, NH3, CO2 and possibly ion transport by an energy independent mechanism. They are found ubiquitously in bacteria, archaeaand eukaryotes. The MIP family contains two major groups of channels: aquaporins and glycerol facilitators.The known aquaporins cluster loosely together as do the known glycerol facilitators. MIP family proteins are believed to form aqueous pores that selectively allow passive transport of their solute(s) across the membrane with minimal apparent recognition. Aquaporins selectively transport water (but not glycerol) while glycerol facilitators selectively transport glycerol but not water. Some aquaporins can transport NH3 and CO2. Glycerol facilitators function as solute nonspecific channels, and may transport glycerol, dihydroxyacetone, propanediol, urea and other small neutral molecules in physiologically importantprocesses. Some members of the family, including the yeast FPS protein (TC #1.A.8.5.1) and tobacco NtTIPA may transport both water and small solutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273306 [Multi-domain]  Cd Length: 216  Bit Score: 219.86  E-value: 1.05e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631  57 AEFIATFLFLYITVLTVMGVKRApNMCASVGIQ---GIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTRA 133
Cdd:TIGR00861   1 AEFLGTFLLVFFGVGSALGVNVA-GAYGAVGGGqflGVALAFGLAVATLVYCVGGISGAHLNPAVTIALLLGRRFPLKRV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 134 VFYMIMQCLGAICGAGVVKGFQPTPYQTLGGGANTVAHGYTKGSGLGAEIIGTFVLVYTVFSATDaKRSARDSHvpILAP 213
Cdd:TIGR00861  80 PVYIVAQLIGAILGAALLYGLTSGLFPGNLAVNGSASAGVSSGQAFFVEFIGTAILVLVIFATTD-DRNRVPRG--GFAP 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1032282631 214 LPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKdHSWDDHWIFWVGPFIGAALAALYH 274
Cdd:TIGR00861 157 LAIGLLVFLIHLSMGPYTGTGMNPARSLGPALFAGL-AGWGNHWVYWVGPIIGAILGALVY 216
GlpF COG0580
Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) ...
 56-279 8.35e-58

Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) [Carbohydrate transport and metabolism];


Pssm-ID: 440345 [Multi-domain]  Cd Length: 232  Bit Score: 184.95  E-value: 8.35e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631  56 IAEFIATFLFLYITVLTVMGVKRAPnmcASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTRAVF 135
Cdd:COG0580     7 LAEFLGTFILVLLGCGVVAVLAGTK---GGIGWLGIALAWGLAVLAGVYAFGHISGAHLNPAVTLALAVAGRFPWKDVLP 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 136 YMIMQCLGAICGAGVVKG-FQPTPYQTLGGGA-NTV-----AHGYTKGSGLGAEIIGTFVLVYTVFSATDAKRSARDshv 208
Cdd:COG0580    84 YIIAQLLGAFLGAALVYLiYGGHFDATEDGGAkLGVfatspAIGYSLGAAFLTEIIGTFVLVFVILGITDKRAAPGG--- 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1032282631 209 piLAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIY--NKDHS-WDDHWIFWVGPFIGAALAALYHQIVIR 279
Cdd:COG0580   161 --LAPLAIGLLVAAIGLSLGPLTGYAINPARDLGPRLFHalGKGGSdWGYLWVPIVAPILGAALAALLYRALFG 232
PLN00027 PLN00027
aquaporin TIP; Provisional
 43-277 3.82e-34

aquaporin TIP; Provisional


Pssm-ID: 177664  Cd Length: 252  Bit Score: 124.51  E-value: 3.82e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631  43 PGELSSWSFYRAGIAEFIATFLFLYITVLTVMGVKR----APNMCASVGIQGIAWAFGgmIFALVYCTAGISGGHINPAV 118
Cdd:PLN00027   11 PGEASHPDALKAALAEFISTLIFVFAGEGSGMAFNKltdnGSTTPAGLVAAALAHAFA--LFVAVSVGANISGGHVNPAV 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 119 TFGLFLARKLSLTRAVFYMIMQCLGAICGAGVVKgfqptpYQTlgGGANTVAHGYTKGSG----LGAEIIGTFVLVYTVF 194
Cdd:PLN00027   89 TFGAFIGGNITLLRGILYWIAQLLGSVVACLLLK------FST--GGLETSAFSLSSGVGvwnaFVFEIVMTFGLVYTVY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 195 -SATDAKRsardSHVPILAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIynkDHSWDDHWIFWVGPFIGAALAALY 273
Cdd:PLN00027  161 aTAVDPKK----GDLGIIAPIAIGFIVGANILAGGAFDGASMNPAVSFGPAVV---SWTWTNHWVYWAGPLIGGGIAGLV 233


                  ....
gi 1032282631 274 HQIV 277
Cdd:PLN00027  234 YELI 237
PLN00166 PLN00166
aquaporin TIP2; Provisional
 44-274 1.04e-32

aquaporin TIP2; Provisional


Pssm-ID: 165733  Cd Length: 250  Bit Score: 120.43  E-value: 1.04e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631  44 GELSSWSFYRAGIAEFIATFLFLYITVLTVMGVKRAPNMCA--SVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFG 121
Cdd:PLN00166   10 GDSFSVASLKAYLSEFIATLLFVFAGVGSAIAFAKLTSDAAldPAGLVAVAVAHAFALFVGVSIAANISGGHLNPAVTLG 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 122 LFLARKLSLTRAVFYMIMQCLGAICGAGVVKgfqptpYQTLGGGANT--VAHGYTKGSGLGAEIIGTFVLVYTVF-SATD 198
Cdd:PLN00166   90 LAIGGNITIITGFFYWIAQCLGSIVACLLLV------FVTNGESVPThgVAAGLGAIEGVVMEIVVTFALVYTVYaTAAD 163

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1032282631 199 AKRSArdshVPILAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNkdhSWDDHWIFWVGPFIGAALAALYH 274
Cdd:PLN00166  164 PKKGS----LGTIAPIAIGFIVGANILAAGPFSGGSMNPARSFGPAVVSG---DFSQIWIYWVGPLVGGALAGLIY 232
PRK05420 PRK05420
aquaporin Z; Provisional
 56-272 6.83e-32

aquaporin Z; Provisional


Pssm-ID: 235453 [Multi-domain]  Cd Length: 231  Bit Score: 117.76  E-value: 6.83e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631  56 IAEFIATFlflyitVLTVMGVKRA------PNMcaSVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLS 129
Cdd:PRK05420    6 AAEFFGTF------WLVFGGCGSAvlaaafPEL--GIGFLGVALAFGLTVLTMAYAVGHISGGHFNPAVSVGLWAGGRFP 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 130 LTRAVFYMIMQCLGAICGAGVV-------KGFQPTpyqTLGGGANTVAH----GYTKGSGLGAEIIGTFVLVYTVFSATD 198
Cdd:PRK05420   78 AKELVPYIIAQVVGGIAAAAVLyliasgkAGFDLA---GSGFASNGYGEhspgGYSLLAALVCEVVLTAFFLLVILGATD 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1032282631 199 AKRSARdshvpiLAPLPIGFAVFLVHLATIPITGTGINPARSLGAAiIYNKDHSWDDHWIFWVGPFIGAALAAL 272
Cdd:PRK05420  155 KRAPAG------FAPIAIGLALTLIHLISIPVTNTSVNPARSTGVA-LFVGGWALEQLWLFWVAPIVGAIIGGL 221
PLN00167 PLN00167
aquaporin TIP5; Provisional
 53-278 1.16e-29

aquaporin TIP5; Provisional


Pssm-ID: 215085  Cd Length: 256  Bit Score: 112.69  E-value: 1.16e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631  53 RAGIAEFIATFLFLYITVLTVMGVKR----APNMCASVGIQGIAWAFGgmIFALVYCTAGISGGHINPAVTFGLFLARKL 128
Cdd:PLN00167   23 RSYLAEFISTFFFVFAAVGSAMSSRKlmpdAASDPSSLLIVAIANAFA--LSSAVYIAANISGGHVNPAVTFGMAVGGHI 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 129 SLTRAVFYMIMQCLGAICGAGVVKGF---QPTPYQTLGGgantvahgytKGSGLGAEIIG---TFVLVYTVFSATDAKRS 202
Cdd:PLN00167  101 SVPTAMFYWISQMLASVMACLFLKVTtvgQHVPTYKIAE----------EMTGFGASVLEgvlTFGLVYTVYAAGDPRRG 170

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1032282631 203 ARDShvpiLAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKdhsWDDHWIFWVGPFIGAALAALYHQIVI 278
Cdd:PLN00167  171 LLGA----IGPLAIGLVAGANVLAAGPFSGGSMNPACAFGSAVVAGS---FKNQAVYWVGPLLGGAVAGLLYDNVV 239
PLN00184 PLN00184
aquaporin NIP1; Provisional
 37-277 3.90e-20

aquaporin NIP1; Provisional


Pssm-ID: 177778  Cd Length: 296  Bit Score: 87.77  E-value: 3.90e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631  37 PAPLFEPGELSSWS--FYRAGIAEFIATFLFLYITVLTVMGVKRAPNmcaSVGIQGIAWAFGGMIFALVYCTAGISGGHI 114
Cdd:PLN00184   37 PKPLKKQDSLLSVSvpFLQKLIAEVLGTYFLVFTGCASVVVNMQNDN---VVTLPGIAIVWGLTIMVLIYSLGHISGAHI 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 115 NPAVTFGLFLARKLSLTRAVFYMIMQCLGAICGAGVVKGFQPTPYQTLGGGANTVAHGYTKGSGLGA---EIIGTFVLVY 191
Cdd:PLN00184  114 NPAVTIAFASCGRFPLKQVPAYVISQVIGSTLAAATLRLLFGLDHDVCSGKHDVFIGSSPVGSDLQAfvmEFIVTFYLMF 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 192 TVFSATDAKRSARDshvpiLAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNkdhSWDDHWIFWVGPFIGAALAA 271
Cdd:PLN00184  194 IISGVATDNRAIGE-----LAGLAIGSTVLLNVLIAAPVSSASMNPGRSLGPAMVYG---CYKGIWIYIVAPTLGAIAGA 265


                  ....*.
gi 1032282631 272 LYHQIV 277
Cdd:PLN00184  266 WVYNTV 271
PTZ00016 PTZ00016
aquaglyceroporin; Provisional
 33-278 5.10e-19

aquaglyceroporin; Provisional


Pssm-ID: 240230 [Multi-domain]  Cd Length: 294  Bit Score: 84.79  E-value: 5.10e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631  33 KEPPPAPLF-EPGELSSWsfYRAGIAEFIATFLFLYITVLTVMGVKRAPNMCASVGIQgIAWAFGgmIFALVYCTAGISG 111
Cdd:PTZ00016   32 KRPPGGQNFwAPREYRPN--VREYVAEFLGTFVLLFFGEGVVATTHTVGNNGDYLAIT-IGWGLG--VTFGLLVSAGISG 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 112 GHINPAVTFGLFLARKLSLTRAVFYMIMQCLGAICGA----GVVKGF---QPTPYQTLGGGANTVAHGYTKGSGLGA--- 181
Cdd:PTZ00016  107 GHLNPAVTLGNAVFGKFPWKKLPGYFVAQLLGAFVGAacvyGLYYGFfkdHGIPELPWETMANGFAGVFATYPREGNfya 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 182 ---EIIGTFVLVYTVFSATDAKRSARDSHVpilaPLPIGFAVFLVHLATIPITGTGINPARSLGA----AIIYNKDHSWD 254
Cdd:PTZ00016  187 ifsELILTAILLLVILAITDPNNCPAFNYL----PVAVGLLVFVIGISFGGNTGYALNPARDLGPrlfsAILWGSEVFTK 262

                         250       260
                  ....*....|....*....|....*...
gi 1032282631 255 DHWIFW---VGPFIGAALAA-LYHQIVI 278
Cdd:PTZ00016  263 DNYYFWvplVAPFVGAVLGMfLYDKFIP 290
PLN00182 PLN00182
putative aquaporin NIP4; Provisional
 56-267 1.18e-18

putative aquaporin NIP4; Provisional


Pssm-ID: 165748  Cd Length: 283  Bit Score: 83.42  E-value: 1.18e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631  56 IAEFIATflflYITVLTVMGVKRAPNM-CASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTRAV 134
Cdd:PLN00182   46 IAEMIGT----YFIIFSGCGVVVVNVLyGGTITFPGICVTWGLIVMVMIYSTGHISGAHFNPAVTVTFAIFRRFPWYQVP 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 135 FYMIMQCLGAICGAGVVK-GFQPTPYQTLGgganTVAHGyTKGSGLGAEIIGTFVLVYTVFSATDAKRSARDshvpiLAP 213
Cdd:PLN00182  122 LYIGAQLTGSLLASLTLRlMFNVTPEAFFG----TTPTD-SSGQALVAEIIISFLLMFVISGVATDSRAVGE-----LAG 191

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1032282631 214 LPIGFAVFLVHLATIPITGTGINPARSLGAAIIYnkdHSWDDHWIFWVGPFIGA 267
Cdd:PLN00182  192 IAVGMTIILNVFVAGPISGASMNPARSLGPAIVM---GRYKGIWVYIVGPFVGI 242
PLN00183 PLN00183
putative aquaporin NIP7; Provisional
 53-287 1.45e-17

putative aquaporin NIP7; Provisional


Pssm-ID: 215092  Cd Length: 274  Bit Score: 80.29  E-value: 1.45e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631  53 RAGIAEFIATFLFLYiTVLTVMGVKRApnMCASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTR 132
Cdd:PLN00183   46 RMVLAEMVGTFILMF-CVCGIIASTQL--SGGEVGLLEYAATAGLTVVVVVFSIGSISGAHVNPSVTIAFATFGHFPWSK 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 133 AVFYMIMQCLGAICGAGVVKgfqptpyQTLGGGANTVAHGYTKG--SGLGAEIIGTFVLVYTVFSATDAKRSARDshvpi 210
Cdd:PLN00183  123 VPLYITAQTVGSVLATYVGV-------SVYGVKADLMTTKPAQGcsSAFWVEFIATFIVMFLAASLTSQPQSLGH----- 190

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 211 LAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIynkdhSWD--DHWIFWVGPFIGAALAAL-YHQIVIRAIPFKSKS 287
Cdd:PLN00183  191 LSGFVIGIAIGLAVLITGPVSGGSMNPARSLGPAIV-----SWDfkDIWIYITAPTIGAVAGALmFHLLRLRTQPCSPNS 265
PLN00026 PLN00026
aquaporin NIP; Provisional
 50-277 1.56e-14

aquaporin NIP; Provisional


Pssm-ID: 177663 [Multi-domain]  Cd Length: 298  Bit Score: 72.20  E-value: 1.56e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631  50 SFYRAGIAEFIATFLFLYITVLTVMGVKRAPNmcaSVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLS 129
Cdd:PLN00026   69 SLTRKLGAEFVGTFILIFAATAGPIVNQKYDG---AETLIGNAACAGLAVMIVILSTGHISGAHLNPSLTIAFAALRHFP 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 130 LTRAVFYMIMQCLGAICGAGVVKG-FQPtpyqTLGGGANTVAHGYtkGSGLGAEIIGTFVLVYTVFS-ATDAKRsardsh 207
Cdd:PLN00026  146 WKHVPAYIAAQVSASICASFALKGvFHP----FMSGGVTVPSVST--GQAFALEFIITFNLLFVVTAvATDTRA------ 213

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282631 208 VPILAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNkdhSWDDHWIFWVGPFIGAALAALYHQIV 277
Cdd:PLN00026  214 VGELAGIAVGATVMLNILVAGPSTGGSMNPVRTLGPAVAAG---NYRAIWIYLVAPTLGALAGAGTYTAV 280
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH