|
Name |
Accession |
Description |
Interval |
E-value |
| pgi |
PRK14096 |
glucose-6-phosphate isomerase; Provisional |
70-604 |
0e+00 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 237609 [Multi-domain] Cd Length: 528 Bit Score: 968.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 70 DPDALWKRYLDWFYQQKELGLYLDISRVGFTDEFVAEMEPRFQAAFKAMEDLEKGSIANPDEGRMVGHYWLRNSKLAPKP 149
Cdd:PRK14096 2 DALQLWQRYCDWLYYHPELGLWLDISRMNFDDAFLESLEPKFQKAFAAMAALEAGAIANPDEGRMVGHYWLRNPELAPTP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 150 TLKTLIENTLDSICAFSDDIISGKIKPPSSpeGRFTQILSVGIGGSALGPQFVAEALAPDNPPLKIRFIDNTDPAGIDHQ 229
Cdd:PRK14096 82 EIRAEITETLAQIEAFAAKVHSGTIKPPNG--EKFTDVLWIGIGGSALGPQFVAEALQPNSDGLNIHFIDNTDPDGIDRV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 230 IAQLGPELASTLVVVISKSGGTPETRNGLLEVQKAFREAGLNFAKQGVAITQENSLLDNTARIEGWLARFPMYDWVGGRT 309
Cdd:PRK14096 160 LAELGDRLATTLVVVISKSGGTPETRNGMLEAKAAYEAAGLDFASHAVAITMKGSKLDQLAQSEGWLARFPMWDWVGGRT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 310 SIMSAVGLLPAALQGINVREMLTGAALMDEATRTTSIKNNPAALLAMCWYWASNGVGSKDMVVLPYKDSLLLFSRYLQQL 389
Cdd:PRK14096 240 SETSAVGLLPAALQGIDIRAFLAGAKQMDEATRVPDLKNNPAALLALAWYYAGDGKGKKDMVVLPYKDRLLLFSRYLQQL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 390 VMESLGKEFDLDGNTVNQGLTVYGNKGSTDQHAYIQQLRDGVHNFFATFIEVLRDRpPGHDWELEPGVTCGDYLFGMLQG 469
Cdd:PRK14096 320 VMESLGKELDLDGNVVHQGIAVYGNKGSTDQHAYVQQLRDGVDNFFVTFIEVLEDR-QGSSIEVEPGVTSGDYLSGFLQG 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 470 TRSALYANGRESISVTIQEVTPTSVGAIIALYERAVGLYASIVNINAYHQPGVEAGKKAAAEVLALQKRVLSVLneatcK 549
Cdd:PRK14096 399 TRQALYENGRQSITITIPEVNPRTLGALIALFERAVGLYASLVNINAYHQPGVEAGKKAAAAILDLQKKVEELL-----K 473
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*
gi 1032282607 550 DPVEPLTLEEIADRCHAPEEIEMIYKIIAHMSANDRVLIAEGNCGSPRSIKVYLG 604
Cdd:PRK14096 474 EDGGELSIEEIAAALGAPEQVETIYKILRHLAANNRGVVLEGDWSNPASLRISKG 528
|
|
| Pgi |
COG0166 |
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate ... |
70-537 |
0e+00 |
|
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439936 Cd Length: 484 Bit Score: 537.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 70 DPDALW---KRYLDWFYQqkELGLYLDISRVGFTDEFVAEMEPrFQAAFKAMEDLEKGSIANPDEGRMVGHYWLRNskLA 146
Cdd:COG0166 2 TQTPAWqhlRRFERFSLE--AAGLLLDYSKNRITDETLELLLE-LAEEEEAREALFAGEKINPTEGRAVLHGALRL--PE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 147 PKPTLKTLIENTLDSICAFSDDIISGKikppsspegRFTQILSVGIGGSALGPQFVAEALAPD-NPPLKIRFIDNTDPAG 225
Cdd:COG0166 77 AGEDVMPEVREELARIKAFAEKVRTGK---------RITDVVNIGIGGSDLGPRAVIEALKPYfRDGPRVHFVSNVDPDY 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 226 IDHQIAQLGPElaSTLVVVISKSGGTPETRNGLLEVQKAFREAGL-NFAKQGVAITQENSLLDNTARIEGWLArFPMYDW 304
Cdd:COG0166 148 LAELLAGLDPE--TTLFIVISKSGTTQETLTNARVAREWLEKAGGeDAAKHFVAVTDNAGALRAFGIDEGYNT-FPFPDW 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 305 VGGRTSIMSAVGLLPAALQGINVREMLTGAALMDEATRTTSIKNNPAALLAMCWYWASNGVGSKDMVVLPYKDSLLLFSR 384
Cdd:COG0166 225 VGGRYSVLSAVGLLPAAAIGIDFEELLAGAHAMDEHFRTAPLEENPPVLLALLGIWYRNFKGAETEAVLPYDQRLERFPA 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 385 YLQQLVMESLGKEFDLDGNTVNQGLTVYGNKGSTDQHAYIQQLRDGVHNFFATFIEVLRDRPPGHDW--------ELEPG 456
Cdd:COG0166 305 WLQQLWMESNGKSVDRDGNPVGYGTGPVGEPGTTDQHSFGQLLHQGTRDIPVTFIAVAEPHHDIPDLllanlqglALLAG 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 457 VTCGDYLFGMLQGTRSALYANGRESISVTIQEVTPTSVGAIIALYERAVGLYASIVNINAYHQPGVEAGKKAAAEVLALQ 536
Cdd:COG0166 385 KTLDEVLALAAEATPHALFPGNRPSNTILLPKLTPYTLGALIALYEHAVFVQGVLWGINPFDQPGVELGKKLAFALLGKL 464
|
.
gi 1032282607 537 K 537
Cdd:COG0166 465 G 465
|
|
| PGI |
pfam00342 |
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of ... |
93-533 |
3.64e-66 |
|
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate.
Pssm-ID: 395271 Cd Length: 487 Bit Score: 224.28 E-value: 3.64e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 93 DISRVGFTDE----FVAEMEPR-FQAAFKAMEDLEKgsiANPDEGRMVGHYWLRNSKLAP----KPTLKTLIENTLDSIC 163
Cdd:pfam00342 1 DYSKNHINDEiltaLVKLAEERgVDAAREAMFNGEK---INSTENRAVLHVALRNRSNTPiyvdGKDVMPEVNAVLAKMK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 164 AFSDDIISGKIKPPSSpeGRFTQILSVGIGGSALGPQFVAEALAPD-NPPLKIRFIDNTDPAGIDHQIAQLGPElaSTLV 242
Cdd:pfam00342 78 SFSERVRSGEWKGYTG--KAITDVVNIGIGGSDLGPVMVTEALKPYsGRDLDVHFVSNVDGTHIAEVLKKLNPE--TTLF 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 243 VVISKSGGTPETRNGLLEVQKAFREAGLN---FAKQGVAITQENSLLD----NTARIegwlarFPMYDWVGGRTSIMSAV 315
Cdd:pfam00342 154 IVASKTFTTAETMTNAESAKEWLLKALKDdsaVAKHFIALSTNAEKVEefgiDTKNM------FEFWDWVGGRYSLWSAI 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 316 GLlPAALQ-GI-NVREMLTGAALMDEATRTTSIKNNPAALLAMCWYWASNGVGSKDMVVLPYKDSLLLFSRYLQQLVMES 393
Cdd:pfam00342 228 GL-PIALSiGFeNFQQLLEGAHAMDKHFLSAPPEKNIPVLLALLGVWYNNFFGAQTHAILPYDQYLHRFPAYLQQLDMES 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 394 LGKEFDLDGNTVN--QGLTVYGNKGSTDQHAYIQ--------------------QLRDGVH------NFFATFIEVLRDR 445
Cdd:pfam00342 307 NGKYVTRDGVLVDhqTGPIIFGEPGTNGQHAFYQlihqgtrlipcdfigavqsqNPENGDHhkillsNFFAQTEALMVGK 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 446 PPGH-DWELEPGVTCGDYLFGMLQGtrsalyanGRESISVTIQEVTPTSVGAIIALYERAVGLYASIVNINAYHQPGVEA 524
Cdd:pfam00342 387 SPEEvRKELAAADVEHLIPHKTFTG--------NRPSNSILVQKLTPATLGALIAMYEHKIFVQGAIWGINSFDQWGVEL 458
|
....*....
gi 1032282607 525 GKKAAAEVL 533
Cdd:pfam00342 459 GKVLAKSIL 467
|
|
| SIS_PGI_2 |
cd05016 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
368-532 |
9.45e-57 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240147 Cd Length: 164 Bit Score: 188.58 E-value: 9.45e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 368 KDMVVLPYKDSLLLFSRYLQQLVMESLGKEFDLDGNTVNQGLTVYGNKGSTDQHAYIQQLRDGVHNFFATFIEVLrdRPP 447
Cdd:cd05016 1 KTHALLPYSQRLERFPAWLQQLDMESNGKSVTRDGEDYPTGPIPWGAPGTNDQHSFFQLIHQGTKDKPVDFIAVK--KPQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 448 GHDWELEPGVTCGDYLFGMLQGTRSAL-YANGRESISVTIQEVTPTSVGAIIALYERAVGLYASIVNINAYHQPGVEAGK 526
Cdd:cd05016 79 NDVLDYLAGKTLHDLLLANCLATREALmFPGGRPSNTIVLPELTPYTLGALLALYEHKTAVQGALLGINPFDQPGVELGK 158
|
....*.
gi 1032282607 527 KAAAEV 532
Cdd:cd05016 159 KLAKKI 164
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pgi |
PRK14096 |
glucose-6-phosphate isomerase; Provisional |
70-604 |
0e+00 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 237609 [Multi-domain] Cd Length: 528 Bit Score: 968.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 70 DPDALWKRYLDWFYQQKELGLYLDISRVGFTDEFVAEMEPRFQAAFKAMEDLEKGSIANPDEGRMVGHYWLRNSKLAPKP 149
Cdd:PRK14096 2 DALQLWQRYCDWLYYHPELGLWLDISRMNFDDAFLESLEPKFQKAFAAMAALEAGAIANPDEGRMVGHYWLRNPELAPTP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 150 TLKTLIENTLDSICAFSDDIISGKIKPPSSpeGRFTQILSVGIGGSALGPQFVAEALAPDNPPLKIRFIDNTDPAGIDHQ 229
Cdd:PRK14096 82 EIRAEITETLAQIEAFAAKVHSGTIKPPNG--EKFTDVLWIGIGGSALGPQFVAEALQPNSDGLNIHFIDNTDPDGIDRV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 230 IAQLGPELASTLVVVISKSGGTPETRNGLLEVQKAFREAGLNFAKQGVAITQENSLLDNTARIEGWLARFPMYDWVGGRT 309
Cdd:PRK14096 160 LAELGDRLATTLVVVISKSGGTPETRNGMLEAKAAYEAAGLDFASHAVAITMKGSKLDQLAQSEGWLARFPMWDWVGGRT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 310 SIMSAVGLLPAALQGINVREMLTGAALMDEATRTTSIKNNPAALLAMCWYWASNGVGSKDMVVLPYKDSLLLFSRYLQQL 389
Cdd:PRK14096 240 SETSAVGLLPAALQGIDIRAFLAGAKQMDEATRVPDLKNNPAALLALAWYYAGDGKGKKDMVVLPYKDRLLLFSRYLQQL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 390 VMESLGKEFDLDGNTVNQGLTVYGNKGSTDQHAYIQQLRDGVHNFFATFIEVLRDRpPGHDWELEPGVTCGDYLFGMLQG 469
Cdd:PRK14096 320 VMESLGKELDLDGNVVHQGIAVYGNKGSTDQHAYVQQLRDGVDNFFVTFIEVLEDR-QGSSIEVEPGVTSGDYLSGFLQG 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 470 TRSALYANGRESISVTIQEVTPTSVGAIIALYERAVGLYASIVNINAYHQPGVEAGKKAAAEVLALQKRVLSVLneatcK 549
Cdd:PRK14096 399 TRQALYENGRQSITITIPEVNPRTLGALIALFERAVGLYASLVNINAYHQPGVEAGKKAAAAILDLQKKVEELL-----K 473
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*
gi 1032282607 550 DPVEPLTLEEIADRCHAPEEIEMIYKIIAHMSANDRVLIAEGNCGSPRSIKVYLG 604
Cdd:PRK14096 474 EDGGELSIEEIAAALGAPEQVETIYKILRHLAANNRGVVLEGDWSNPASLRISKG 528
|
|
| PLN02649 |
PLN02649 |
glucose-6-phosphate isomerase |
62-588 |
0e+00 |
|
glucose-6-phosphate isomerase
Pssm-ID: 215351 [Multi-domain] Cd Length: 560 Bit Score: 738.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 62 DSKKELLKDPDALWKRYLDWFYQ-----QKEL---------------GLYLDISRVGFTDEFVAEMEPRFQAA--FKAME 119
Cdd:PLN02649 1 TTKKTLLISDTPAWKRLVAHVYQikkthLRELlndaercqsmiaefdGIYLDYSRQRVTDETMELLFPLAEAAnlFEKIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 120 DLEKGSIANPDEGRMVGHYWLRNSKLAP----KPTLKTLIENTLDSICAFSDDIISGKIKppSSPEGRFTQILSVGIGGS 195
Cdd:PLN02649 81 AMFSGEIINSTEDRAVLHVALRAPRLAPilvdGKNVVPEVWEVLDKIKAFSEDVRSGKWK--GATGKRFTNVVSIGIGGS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 196 ALGPQFVAEALAPDNPPL------KIRFIDNTDPAGIDHQIAQLGPElaSTLVVVISKSGGTPETRNGLLEVQKAFREA- 268
Cdd:PLN02649 159 FLGPLFVHEALATDPEALksakgrKLRFLANVDPVDIARQIAQLDPE--TTLVVVVSKTFTTAETMLNARTVRKWLRDAl 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 269 -GLNFAKQGVAITqENSLLDNTARIEGWLArFPMYDWVGGRTSIMSAVGLLPAALQ-GI-NVREMLTGAALMDEATRTTS 345
Cdd:PLN02649 237 gGLAVAKHMVAVS-TNLLLVNKFGIDPWNA-FPFWDWVGGRYSVCSAVGLLPLSLQyGFdVVEEFLEGAASMDEHFRTAP 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 346 IKNNPAALLAMCWYWASNGVGSKDMVVLPYKDSLLLFSRYLQQLVMESLGKEFDLDGN--TVNQGLTVYGNKGSTDQHAY 423
Cdd:PLN02649 315 LKENIPVLLGLLSVWNSSFLGYPARAILPYSQALLKFAPHIQQLDMESNGKGVDLDGNplPVNTGEIDFGEPGTNGQHSF 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 424 IQQLRDGvHNFFATFIEVLRDRPPGHDWElEPGVTCGDYLFGMLQGTRSAL-----------------------YANGRE 480
Cdd:PLN02649 395 YQLIHQG-RNIPCDFIGVVRSQQPVHLWL-GEGVSNHDELMSNFFAQPDALaygktpeqlraegvpeeliphkvFAGNRP 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 481 SISVTIQEVTPTSVGAIIALYERAVGLYASIVNINAYHQPGVEAGKkaaaevlALQKRVLSVLNEATCK-DPVEPLTLEE 559
Cdd:PLN02649 473 SLSILLPELTAYTVGQLLALYEHRVAVQGFIWNINSFDQWGVELGK-------ALAKRVRAVLNEARTKgEPVEGFNSST 545
|
570 580
....*....|....*....|....*....
gi 1032282607 560 IAdrchapeeiemiykIIAHMSANDRVLI 588
Cdd:PLN02649 546 TA--------------LLNHYLANKRALI 560
|
|
| Pgi |
COG0166 |
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate ... |
70-537 |
0e+00 |
|
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439936 Cd Length: 484 Bit Score: 537.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 70 DPDALW---KRYLDWFYQqkELGLYLDISRVGFTDEFVAEMEPrFQAAFKAMEDLEKGSIANPDEGRMVGHYWLRNskLA 146
Cdd:COG0166 2 TQTPAWqhlRRFERFSLE--AAGLLLDYSKNRITDETLELLLE-LAEEEEAREALFAGEKINPTEGRAVLHGALRL--PE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 147 PKPTLKTLIENTLDSICAFSDDIISGKikppsspegRFTQILSVGIGGSALGPQFVAEALAPD-NPPLKIRFIDNTDPAG 225
Cdd:COG0166 77 AGEDVMPEVREELARIKAFAEKVRTGK---------RITDVVNIGIGGSDLGPRAVIEALKPYfRDGPRVHFVSNVDPDY 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 226 IDHQIAQLGPElaSTLVVVISKSGGTPETRNGLLEVQKAFREAGL-NFAKQGVAITQENSLLDNTARIEGWLArFPMYDW 304
Cdd:COG0166 148 LAELLAGLDPE--TTLFIVISKSGTTQETLTNARVAREWLEKAGGeDAAKHFVAVTDNAGALRAFGIDEGYNT-FPFPDW 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 305 VGGRTSIMSAVGLLPAALQGINVREMLTGAALMDEATRTTSIKNNPAALLAMCWYWASNGVGSKDMVVLPYKDSLLLFSR 384
Cdd:COG0166 225 VGGRYSVLSAVGLLPAAAIGIDFEELLAGAHAMDEHFRTAPLEENPPVLLALLGIWYRNFKGAETEAVLPYDQRLERFPA 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 385 YLQQLVMESLGKEFDLDGNTVNQGLTVYGNKGSTDQHAYIQQLRDGVHNFFATFIEVLRDRPPGHDW--------ELEPG 456
Cdd:COG0166 305 WLQQLWMESNGKSVDRDGNPVGYGTGPVGEPGTTDQHSFGQLLHQGTRDIPVTFIAVAEPHHDIPDLllanlqglALLAG 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 457 VTCGDYLFGMLQGTRSALYANGRESISVTIQEVTPTSVGAIIALYERAVGLYASIVNINAYHQPGVEAGKKAAAEVLALQ 536
Cdd:COG0166 385 KTLDEVLALAAEATPHALFPGNRPSNTILLPKLTPYTLGALIALYEHAVFVQGVLWGINPFDQPGVELGKKLAFALLGKL 464
|
.
gi 1032282607 537 K 537
Cdd:COG0166 465 G 465
|
|
| pgi |
PRK00179 |
glucose-6-phosphate isomerase; Reviewed |
89-534 |
4.93e-75 |
|
glucose-6-phosphate isomerase; Reviewed
Pssm-ID: 234679 Cd Length: 548 Bit Score: 249.32 E-value: 4.93e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 89 GLYLDISRVGFTDEFVAEM-----EPRFQAAFKAMEDlekGSIANPDEGRMVGHYWLRNSKLAP-----KPTLKTlIENT 158
Cdd:PRK00179 46 GLLLDYSKNRITDETLALLldlarEAGLEGARDAMFA---GEKINTTEDRAVLHTALRNPSNTPilvdgQDVMPE-VHAV 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 159 LDSICAFSDDIISGKIKPPSspEGRFTQILSVGIGGSALGPQFVAEALAPD-NPPLKIRFIDNTDPAGIDHQIAQLGPEl 237
Cdd:PRK00179 122 LARMKAFAEAVRSGEWKGYT--GKAITDVVNIGIGGSDLGPVMVTEALRPYaDPGLRVHFVSNVDGAHLAETLKKLDPE- 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 238 aSTLVVVISKSGGTPET-------RNGLLEvqKAFREAGLnfAKQGVAITQenslldNTARIEGW---LAR-FPMYDWVG 306
Cdd:PRK00179 199 -TTLFIVASKTFTTQETltnahsaRDWFLA--AGGDEAAV--AKHFVAVST------NAEAVAEFgidPDNmFGFWDWVG 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 307 GRTSIMSAVGLlPAALQ-GI-NVREMLTGAALMDEATRTTSIKNNPAALLAMCWYWASNGVGSKDMVVLPYKDSLLLFSR 384
Cdd:PRK00179 268 GRYSLWSAIGL-SIALAiGPdNFEELLAGAHAMDEHFRTAPLEKNLPVLLALIGVWYRNFFGAQSHAVLPYDQYLHRFPA 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 385 YLQQLVMESLGKEFDLDGNTVNQ--GLTVYGNKGSTDQHAYIQQLRDGVHNFFATFIEVLR-DRPPG--HDWEL------ 453
Cdd:PRK00179 347 YLQQLEMESNGKSVDRDGTPVDYqtGPIIWGEPGTNGQHAFFQLLHQGTKLVPADFIAPAQpHNPLGdhHDLLLancfaq 426
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 454 ---------EPGVTCGDYLFGMLQGTRSAL-----YANGRESISVTIQEVTPTSVGAIIALYERAVGLYASIVNINAYHQ 519
Cdd:PRK00179 427 tealmfgktAEEVRAELRAKGLDEAEAEELaphkvFPGNRPSTTILLDRLTPFTLGALIALYEHKVFVQGVIWGINSFDQ 506
|
490
....*....|....*
gi 1032282607 520 PGVEAGKKAAAEVLA 534
Cdd:PRK00179 507 WGVELGKQLAKRILP 521
|
|
| PRK00973 |
PRK00973 |
glucose-6-phosphate isomerase; Provisional |
148-533 |
1.93e-68 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 179193 [Multi-domain] Cd Length: 446 Bit Score: 229.11 E-value: 1.93e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 148 KPTLKTLIENTLDSICAFSDDIISGKIKPPSSPEGR---FTQILSVGIGGSALGPQFVAEALAPDN---------PPLKI 215
Cdd:PRK00973 32 TSAVENLMEKEPNGELGFLELPYDRSLDSYEELKEWsknFDNVVVLGIGGSALGNLALHYALNPLNwnelskeerNGPRV 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 216 RFIDNTDPAGIDHQIAQLGPElaSTLVVVISKSGGTPETRNGLLEVQKAFREAGLNFAKQGVAIT-QENSLLDNTARIEG 294
Cdd:PRK00973 112 FVLDNVDPEKTASILDVIDLE--KTLFNVISKSGNTAETLANYLIIRGILEKLGLDPKKHLVFTTdPEKGKLKKIAEKEG 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 295 wlarFPMYDW---VGGRTSIMSAVGLLPAALQGINVREMLTGAALMDEATRTTSIKNNPAALLAMCWYWASNGvGSKDMV 371
Cdd:PRK00973 190 ----YRTLEIpenVGGRFSVLTPVGLAPAAALGIDIEELLEGAKEMDKICEKEDIFKNPALLNALIHYLYYNR-GKNISV 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 372 VLPYKDSLLLFSRYLQQLVMESLGKEfdldgntvNQGLTVYGNKGSTDQHAYIQQLRDGVHNFFATFIEVLRDR-----P 446
Cdd:PRK00973 265 MMPYSERLKYFGDWYRQLWAESLGKK--------GVGQTPVKALGATDQHSQLQLYMEGPKDKIITFLKVEKYRrdveiP 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 447 PGHDWELEP----GVTCGDYLFGMLQGTRSALYANGRESISVTIQEVTPTSVGAIIALYERAVGLYASIVNINAYHQPGV 522
Cdd:PRK00973 337 YEYEDIEELsylgGHKLSELINSEQKGTEIALTENGRPNVKITLDELNEYTVGQLFYMYEMQTAFMGELLNINAFDQPGV 416
|
410
....*....|.
gi 1032282607 523 EAGKKAAAEVL 533
Cdd:PRK00973 417 ELGKKITYALL 427
|
|
| pgi |
PRK14095 |
glucose-6-phosphate isomerase; Provisional |
118-537 |
3.51e-68 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 237608 Cd Length: 533 Bit Score: 231.06 E-value: 3.51e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 118 MEDLEKGSIAN-----PDEGRMVGHY----WLRNSKLAPK-PTLKTLIENTLDSICAFSDDIISGKIKppSSPEGRFTQI 187
Cdd:PRK14095 77 MKAMQNGAVINriegfPSENRPVLHTatrgQVGDSVLTDEaEDMAEFSKRELERLAEFLKKVRSGEIK--NSNGKKFTTV 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 188 LSVGIGGSALGPQFVAEALA----PDNpplKIRFIDNTDP---AGIDHQIaqlgpELASTLVVVISKSGGTPETRNGLLE 260
Cdd:PRK14095 155 VQIGIGGSDLGPKALYLALKnyakKDK---RVHFISNVDPddaAEVLSEI-----DLAKTLFIVVSKSGTTLETAANEEF 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 261 VQKAFREAGLNFAKQGVAITQENSLLDNTariEGWLARFPMYDWVGGRTSIMSAVGLLPAALQ-GINV-REMLTGAALMD 338
Cdd:PRK14095 227 VRDALKKAGLDYKKHFIAVTSEGSPMDDE---SGYLEVFHMWDSIGGRFSSTSMVGGVVLGFAfGFEVfKEFLKGAAAMD 303
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 339 EATRTTSIKNNPAALLAMCWYWASNGVGSKDMVVLPYKDSLLLFSRYLQQLVMESLGKEFDLDGNTVN--QGLTVYGNKG 416
Cdd:PRK14095 304 KAALNPNIRENLPLLAALIGIWNRNFLGYPTTAVIPYSQALERFPAHLQQLDMESNGKSVNRFGEPINfkTGPIIWGEPG 383
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 417 STDQHAYIQQLRDG---VHNFFATFIEVLRdrppGHDWELEpGVTCGDYLFGMLQGTRSALyANGRESI----------- 482
Cdd:PRK14095 384 TNGQHSFFQLLHQGtdiVPVEFIGFKESQL----GQDIVIQ-GSTSQQKLFANLIAQIIAL-ACGKENTnpnknfkgnrp 457
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 1032282607 483 -SVTI-QEVTPTSVGAIIALYERAVGLYASIVNINAYHQPGVEAGKKAAAEVLALQK 537
Cdd:PRK14095 458 sSLLVaKQLTPYTLGALLAHYENKVMFQGFCWNINSFDQEGVQLGKVLANQILGIMK 514
|
|
| PTZ00430 |
PTZ00430 |
glucose-6-phosphate isomerase; Provisional |
89-532 |
7.17e-67 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 185612 Cd Length: 552 Bit Score: 227.98 E-value: 7.17e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 89 GLYLDISRVGFTDEfvaEMEPRFQAA-----FKAMEDLEKGSIANPDEGRMVGHYWLRnsklAPKPTL-----KTLIEN- 157
Cdd:PTZ00430 43 GVTLDLSRQRLDEE---TLKLLIELAeeaklKEKIKDMFNGEKINTTENRAVLHTALR----APRGEKvvvdgKNVLEDv 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 158 --TLDSICAFSDDIISGKIKppSSPEGRFTQILSVGIGGSALGPQFVAEALAPDNPPL------KIRFIDNTDPAGIDHQ 229
Cdd:PTZ00430 116 heVLDRIKKFSDKIRSGEIL--GSTGKKLKNVICIGIGGSYLGTEFVYEALRTYGEAReaskgrKLRFLANVDPIDVRRA 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 230 IAQLGPElaSTLVVVISKSGGTPET-------RNGLLEVQKAFREaglnFAKQGVAITQENSLLD----NTARIegwlar 298
Cdd:PTZ00430 194 TEGLDPE--ETLVVIISKTFTTAETmlnaktvRQWLLDNIKSKEA----LSKHLCAVSTNLKLTSefgiPDENV------ 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 299 FPMYDWVGGRTSIMSAVGLLPAALQ-GIN-VREMLTGAALMDEATRTTSIKNNPAALLAMCWYWASNGVGSKDMVVLPYK 376
Cdd:PTZ00430 262 FGFWDWVGGRFSVTSAVGILPLSIQfGYDiVQQFLNGCHDMDEHFRTAPLEENLPVLLGLTSFYNSTFLGYNCVAILPYC 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 377 DSLLLFSRYLQQLVMESLGKEFDLDGNTVNQ--GLTVYGNKGSTDQHAYIQQLRDG--VHNFFATFIEVLRDrppghDWE 452
Cdd:PTZ00430 342 QALLKFPAHVQQLLMESNGKSVTLDGNTLDYntGEIYFGEPGTNGQHSFYQLLHQGrvVPSEFIGFAKSQNP-----IKL 416
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 453 LEPGVTCGDYL----FGMLQG-----TRSALYANG--------------RESISVTIQEVTPTSVGAIIALYERAVGLYA 509
Cdd:PTZ00430 417 LGEPVSNHDELmsnfFAQPDAlafgkTYEELEKEGvpeeliphkvfpgnRPSLLLLFPELNPYTIGQLLALYEHRTVVEG 496
|
490 500
....*....|....*....|...
gi 1032282607 510 SIVNINAYHQPGVEAGKKAAAEV 532
Cdd:PTZ00430 497 FLWNINSFDQWGVELGKVLAKDV 519
|
|
| PGI |
pfam00342 |
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of ... |
93-533 |
3.64e-66 |
|
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate.
Pssm-ID: 395271 Cd Length: 487 Bit Score: 224.28 E-value: 3.64e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 93 DISRVGFTDE----FVAEMEPR-FQAAFKAMEDLEKgsiANPDEGRMVGHYWLRNSKLAP----KPTLKTLIENTLDSIC 163
Cdd:pfam00342 1 DYSKNHINDEiltaLVKLAEERgVDAAREAMFNGEK---INSTENRAVLHVALRNRSNTPiyvdGKDVMPEVNAVLAKMK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 164 AFSDDIISGKIKPPSSpeGRFTQILSVGIGGSALGPQFVAEALAPD-NPPLKIRFIDNTDPAGIDHQIAQLGPElaSTLV 242
Cdd:pfam00342 78 SFSERVRSGEWKGYTG--KAITDVVNIGIGGSDLGPVMVTEALKPYsGRDLDVHFVSNVDGTHIAEVLKKLNPE--TTLF 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 243 VVISKSGGTPETRNGLLEVQKAFREAGLN---FAKQGVAITQENSLLD----NTARIegwlarFPMYDWVGGRTSIMSAV 315
Cdd:pfam00342 154 IVASKTFTTAETMTNAESAKEWLLKALKDdsaVAKHFIALSTNAEKVEefgiDTKNM------FEFWDWVGGRYSLWSAI 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 316 GLlPAALQ-GI-NVREMLTGAALMDEATRTTSIKNNPAALLAMCWYWASNGVGSKDMVVLPYKDSLLLFSRYLQQLVMES 393
Cdd:pfam00342 228 GL-PIALSiGFeNFQQLLEGAHAMDKHFLSAPPEKNIPVLLALLGVWYNNFFGAQTHAILPYDQYLHRFPAYLQQLDMES 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 394 LGKEFDLDGNTVN--QGLTVYGNKGSTDQHAYIQ--------------------QLRDGVH------NFFATFIEVLRDR 445
Cdd:pfam00342 307 NGKYVTRDGVLVDhqTGPIIFGEPGTNGQHAFYQlihqgtrlipcdfigavqsqNPENGDHhkillsNFFAQTEALMVGK 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 446 PPGH-DWELEPGVTCGDYLFGMLQGtrsalyanGRESISVTIQEVTPTSVGAIIALYERAVGLYASIVNINAYHQPGVEA 524
Cdd:pfam00342 387 SPEEvRKELAAADVEHLIPHKTFTG--------NRPSNSILVQKLTPATLGALIAMYEHKIFVQGAIWGINSFDQWGVEL 458
|
....*....
gi 1032282607 525 GKKAAAEVL 533
Cdd:pfam00342 459 GKVLAKSIL 467
|
|
| SIS_PGI_2 |
cd05016 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
368-532 |
9.45e-57 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240147 Cd Length: 164 Bit Score: 188.58 E-value: 9.45e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 368 KDMVVLPYKDSLLLFSRYLQQLVMESLGKEFDLDGNTVNQGLTVYGNKGSTDQHAYIQQLRDGVHNFFATFIEVLrdRPP 447
Cdd:cd05016 1 KTHALLPYSQRLERFPAWLQQLDMESNGKSVTRDGEDYPTGPIPWGAPGTNDQHSFFQLIHQGTKDKPVDFIAVK--KPQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 448 GHDWELEPGVTCGDYLFGMLQGTRSAL-YANGRESISVTIQEVTPTSVGAIIALYERAVGLYASIVNINAYHQPGVEAGK 526
Cdd:cd05016 79 NDVLDYLAGKTLHDLLLANCLATREALmFPGGRPSNTIVLPELTPYTLGALLALYEHKTAVQGALLGINPFDQPGVELGK 158
|
....*.
gi 1032282607 527 KAAAEV 532
Cdd:cd05016 159 KLAKKI 164
|
|
| SIS_PGI_1 |
cd05015 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
156-322 |
9.05e-56 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240146 Cd Length: 158 Bit Score: 185.81 E-value: 9.05e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 156 ENTLDSICAFSDDIISGKikppsspegRFTQILSVGIGGSALGPQFVAEALAP-DNPPLKIRFIDNTDPAGIDHQIAQLG 234
Cdd:cd05015 1 RAELERIKEFAEKVRSGK---------KITDVVVIGIGGSDLGPRAVYEALKPyFKGGLRLHFVSNVDPDDLAELLKKLD 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 235 PElaSTLVVVISKSGGTPETRNGLLEVQKAFREAGLN-FAKQGVAITQENSLLDNTARIEgWLARFPMYDWVGGRTSIMS 313
Cdd:cd05015 72 PE--TTLFIVISKSGTTLETLANARLAREWLEEAGGDdLAKHFVAITDNGSGLLKKAGIE-GLNTFEIPDWVGGRFSVLS 148
|
....*....
gi 1032282607 314 AVGLLPAAL 322
Cdd:cd05015 149 SVGGLPLAL 157
|
|
| PRK03868 |
PRK03868 |
glucose-6-phosphate isomerase; Provisional |
183-527 |
9.82e-47 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 235168 Cd Length: 410 Bit Score: 169.73 E-value: 9.82e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 183 RFTQILSVGIGGSALGPQFVAEALAPD-NPPLKIRFIDNTDPAGIDHQIAQLGPElaSTLVVVISKSGGTPETRN---GL 258
Cdd:PRK03868 57 SIKNIVVIGIGGSSLGVKAIYSFLKNEkNNKKELHFLENTDPISINKTLSKINLE--NTLFIVISKSGTTIETISifkYL 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 259 LEVQKAFREAGLNFakqgVAITQENSLLDNTARIEGwLARFPMYDWVGGRTSIMSAVGLLPAALQGINVREMLTGAAlmd 338
Cdd:PRK03868 135 LSHFKLDQELKKNF----LFITDPDSKLEQFAKENN-IKCFNIPKNVGGRFSVLSAVGIVPLALCGYDIKALLEGAK--- 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 339 eATRTTSIKNNPAALLAMCWYWASNGVGSKDMVVLPYKDSLLLFSRYLQQLVMESLGKefdLDGNTVNQGLTVYGNKGST 418
Cdd:PRK03868 207 -ACKDSFFEQKEDHILKKAYFYATHKNAYNINVLFSYSDALKGFNDWYVQLWGESLGK---KQGYKTRVGLTPIGLIGSR 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 419 DQHAYIQQLRDGVHNFFATFIEV--LRDRPPGHDWELEPGVTCgDYLFGM-------LQ--GTRSALYANGresISV--- 484
Cdd:PRK03868 283 DQHSFLQLIMEGPRDKTVTFIKIkdFQNAPKIPNISLKGLESL-DFVNGVsfnelinAQcdATMEALIAED---IPVdvi 358
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 1032282607 485 TIQEVTPTSVGAIIALYEravgLYASIV----NINAYHQPGVEAGKK 527
Cdd:PRK03868 359 TLEKLDEFSIGYLIYYYE----LLTSAVgkmlGINTYDQPGVEVGKR 401
|
|
| pgi |
PRK14097 |
glucose-6-phosphate isomerase; Provisional |
190-527 |
1.07e-34 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 184504 Cd Length: 448 Bit Score: 136.89 E-value: 1.07e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 190 VGIGGSALGPQFVAEALapdNPPLKIRFIDNTDPAgidHQIAQLGPELASTL--------------VVVISKSGGTPET- 254
Cdd:PRK14097 79 IGIGGSYLGARAAIEFL---NHSFYNLLPKEQRKA---PQIIFAGNSISSTYladlleylkdkdfsINVISKSGTTTEPa 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 255 ------RNgLLEVQKAFREAglnfAKQGVAITQENS-LLDNTARIEGWlARFPMYDWVGGRTSIMSAVGLLPAALQGINV 327
Cdd:PRK14097 153 iafrifKE-LLEKKYGKEEA----KKRIYATTDKAKgALKTLADAEGY-ETFVIPDDVGGRFSVLTAVGLLPIAVAGIDI 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 328 REMLTGAALMDEATRTTSIKNNPAALLAMCWYWASNGvGSKDMVVLPYKDSLLLFSRYLQQLVMESLGKEfdldgntvNQ 407
Cdd:PRK14097 227 DALMKGAADARKDYSSSDLSENPAYQYAAVRNILYRK-GYTTEILVNYEPSLQYFSEWWKQLFGESEGKD--------QK 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 408 GLTVYGNKGSTDQHA---YIQqlrDGVHNFFATFIEVLRdrpPGHDWELEPGVTCGD---YLFG---------MLQGTRS 472
Cdd:PRK14097 298 GIFPASANFSTDLHSlgqYIQ---EGRRNLFETVIKVEK---PRKDLTIPEDEEDLDglnYLAGktvdfvnkkAFEGTLL 371
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 1032282607 473 ALYANGRESISVTIQEVTPTSVGAIIALYERAVGLYASIVNINAYHQPGVEAGKK 527
Cdd:PRK14097 372 AHTDGGVPNIVVNIPELDEYTFGYLVYFFEKACAISGYLLGVNPFDQPGVEAYKK 426
|
|
| PRK09533 |
PRK09533 |
bifunctional transaldolase/phosoglucose isomerase; Validated |
181-534 |
1.10e-25 |
|
bifunctional transaldolase/phosoglucose isomerase; Validated
Pssm-ID: 236551 [Multi-domain] Cd Length: 948 Bit Score: 112.76 E-value: 1.10e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 181 EGRFTQILSVGIGGSALGPQFVAEALAPDNPPLKIRFIDNTDPAGIDHQIAQLgpELASTLVVVISKSGGTPETrNGLL- 259
Cdd:PRK09533 452 AEGFTDAVVLGMGGSSLGPEVLAETFGQRDGFPKLHVLDSTDPAQVRALEAAV--DLARTLFIVSSKSGGTLEP-NIFKd 528
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 260 ----EVQKAFRE-AGLNFakqgVAITQENSLLDNTARIEGWLARFPMYDWVGGRTSIMSAVGLLPAALQGINVREMLTGA 334
Cdd:PRK09533 529 yffaRVKEVLGAkAGRHF----VAVTDPGSSLEKVAKEDGFRKIFHGDPDIGGRYSVLSPFGLVPAAAAGIDVRALLDSA 604
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 335 ALMDEATRT-TSIKNNPAALL--AMcwywasnGVGS---KDMVVLPYKDSLLLFSRYLQQLVMESLGKE----FDLDGNT 404
Cdd:PRK09533 605 LAMVRSCGPsVPPADNPGVQLglAL-------GVAAtqgRDKVTIVASPAIADFGAWAEQLIAESTGKEgkglIPIDGEP 677
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 405 VNqGLTVYGNkgstDQhayiqqlrdgvhnFFATfIEVLRDRPPGHDWELepgvtcgdylfgmlqgtrSALYANGRESISV 484
Cdd:PRK09533 678 LG-DPAVYGN----DR-------------VFVY-LRLAGEADAAQDAAL------------------AALEAAGHPVVRI 720
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 1032282607 485 TIQEvtPTSVGAIIALYERAVGLYASIVNINAYHQPGVEAGKKAAAEVLA 534
Cdd:PRK09533 721 VLDS--AEQLGQEFFRWEMATAVAGAVLGINPFDQPDVEASKIKTRELTA 768
|
|
| SIS_PGI_PMI_1 |
cd05017 |
The members of this protein family contain the SIS (Sugar ISomerase) domain and have both the ... |
191-295 |
2.96e-03 |
|
The members of this protein family contain the SIS (Sugar ISomerase) domain and have both the phosphoglucose isomerase (PGI) and the phosphomannose isomerase (PMI) functions. These functions catalyze the reversible reactions of glucose 6-phosphate to fructose 6-phosphate, and mannose 6-phosphate to fructose 6-phosphate, respectively at an equal rate. This protein contains two SIS domains. This alignment is based on the first SIS domain.
Pssm-ID: 240148 [Multi-domain] Cd Length: 119 Bit Score: 38.01 E-value: 2.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032282607 191 GIGGSALGPQFVAEALAPDNPPLKIRFIDNTDPAGIDhqiaqlgpelASTLVVVISKSGGTPETRNGLLEVQKAfreagl 270
Cdd:cd05017 6 GMGGSGIGGDLLESLLLDEAKIPVYVVKDYTLPAFVD----------RKTLVIAVSYSGNTEETLSAVEQAKER------ 69
|
90 100
....*....|....*....|....*
gi 1032282607 271 nfAKQGVAITQeNSLLDNTARIEGW 295
Cdd:cd05017 70 --GAKIVAITS-GGKLLEMAREHGV 91
|
|
| |
