|
Name |
Accession |
Description |
Interval |
E-value |
| PBP1_ABC_LIVBP-like |
cd06342 |
type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active ... |
15-345 |
9.18e-99 |
|
type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); This subgroup includes the type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine). This subgroup also includes a leucine-specific binding protein (or LivK), which is very similar in sequence and structure to leucine-isoleucine-valine binding protein (LIVBP). ABC-type active transport systems are transmembrane proteins that function in the transport of diverse sets of substrates across extra- and intracellular membranes, including carbohydrates, amino acids, inorganic ions, dipeptides and oligopeptides, metabolic products, lipids and sterols, and heme, to name a few.
Pssm-ID: 380565 [Multi-domain] Cd Length: 334 Bit Score: 295.59 E-value: 9.18e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 15 VIALAAPLAGES-ILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMVKNGISAVIGHACSGASV 93
Cdd:cd06342 1 KIGVAGPLTGPNaALGQDIRNGAELAVDEINAKGGGLGFKIELVAQDDACDPAQAVAAAQKLVADGVVAVIGHYNSGAAI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 94 PASLVYQEDGVLMLSPSSSVPKLTERGLDLVFRLFGRDDRLADAMANHVARKYADKQIAVIHDKRSYGKGLADGFKDGLN 173
Cdd:cd06342 81 AAAPIYAEAGIPMISPSATNPKLTEQGYKNFFRVVGTDDQQGPAAADYAAKTLKAKRVAVIHDGTAYGKGLADAFKKALK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 174 KRKLREAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAASPAAFWQAAGPAAEG 253
Cdd:cd06342 161 ALGGTVVGREGITPGTTDFSALLTKIKAANPDAVYFGGYYPEAGLLLRQLREAGLKAPFMGGDGIVSPDFIKAAGDAAEG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 254 VVFASIAADPT-FEGLDAIGKALIEA-GRPVTIYGLSAYAAVTVFAQAVRHAKSAEPKAVAAALHANEFATPLGNVRFSH 331
Cdd:cd06342 241 VYATTPGAPPEkLPAAKAFLKAYKAKfGEPPGAYAAYAYDAAQVLLAAIEKAGSTDRAAVAAALRATDFDGVTGTISFDA 320
|
330
....*....|....
gi 1032077502 332 SGDALGIRYQISRW 345
Cdd:cd06342 321 KGDLTGPAFTVYQV 334
|
|
| PRK15404 |
PRK15404 |
high-affinity branched-chain amino acid ABC transporter substrate-binding protein; |
1-345 |
1.08e-75 |
|
high-affinity branched-chain amino acid ABC transporter substrate-binding protein;
Pssm-ID: 237959 [Multi-domain] Cd Length: 369 Bit Score: 238.00 E-value: 1.08e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 1 MILVAPTTPALAEVV-IALAAPLAGE-SILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMVKN 78
Cdd:PRK15404 12 CIALALSHAALADDIkIAIVGPMSGPvAQYGDMEFTGARQAIEDINAKGGIKGDKLEGVEYDDACDPKQAVAVANKVVND 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 79 GISAVIGHACSGASVPASLVYQEDGVLMLSPSSSVPKLTERGLDLVFRLFGRDDRLADAMANHVARKYADKQIAVIHDKR 158
Cdd:PRK15404 92 GIKYVIGHLCSSSTQPASDIYEDEGILMITPAATAPELTARGYQLIFRTIGLDSDQGPTAAKYILEKVKPKRIAVLHDKQ 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 159 SYGKGLADGFKDGLNKRKLREAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAA 238
Cdd:PRK15404 172 QYGEGLARSVKDGLKKAGANVVFFEGITAGDKDFSALIAKLKKENVDFVYYGGYHPEMGQILRQAREAGLKTQFMGPEGV 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 239 SPAAFWQAAGPAAEGVVF---ASIAADPTFEgldAIGKALIEAGR-PVTIYGLSAYAAVTVFAQAVRHAKSAEPKAVAAA 314
Cdd:PRK15404 252 GNKSLSNIAGPASEGMLVtlpKRYDQDPANK---AIVDAFKAKKQdPSGPFVWTTYAAVQSLAAGINRAGSDDPAKVAKY 328
|
330 340 350
....*....|....*....|....*....|.
gi 1032077502 315 LHANEFATPLGNVRFSHSGDALGIRYQISRW 345
Cdd:PRK15404 329 LKANTFDTVIGPLSWDEKGDLKGFEFGVFEW 359
|
|
| LivK |
COG0683 |
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid ... |
12-348 |
2.59e-54 |
|
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid transport and metabolism];
Pssm-ID: 440447 [Multi-domain] Cd Length: 314 Bit Score: 180.90 E-value: 2.59e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 12 AEVVIALAAPLAG-ESILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMV-KNGISAVIGHACS 89
Cdd:COG0683 2 DPIKIGVLLPLTGpYAALGQPIKNGAELAVEEINAAGGVLGRKIELVVEDDASDPDTAVAAARKLIdQDKVDAIVGPLSS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 90 GASVPASLVYQEDGVLMLSPSSSVPKLTER-GLDLVFRLFGRDDRLADAMANHVARKYADKQIAVIHDKRSYGKGLADGF 168
Cdd:COG0683 82 GVALAVAPVAEEAGVPLISPSATAPALTGPeCSPYVFRTAPSDAQQAEALADYLAKKLGAKKVALLYDDYAYGQGLAAAF 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 169 KDGLNKRKLREAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFftgeaaspaafwqaag 248
Cdd:COG0683 162 KAALKAAGGEVVGEEYYPPGTTDFSAQLTKIKAAGPDAVFLAGYGGDAALFIKQAREAGLKGPL---------------- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 249 paaegvvfasiaadptfegldaiGKALIEA-----GRPVTIYGLSAYAAVTVFAQAVRHAKSAEPKAVAAALHANEFATP 323
Cdd:COG0683 226 -----------------------NKAFVKAykakyGREPSSYAAAGYDAALLLAEAIEKAGSTDREAVRDALEGLKFDGV 282
|
330 340
....*....|....*....|....*
gi 1032077502 324 LGNVRFSHSGDALGiRYQISRWSNG 348
Cdd:COG0683 283 TGPITFDPDGQGVQ-PVYIVQVKAD 306
|
|
| PBP1_ABC_transporter_LIVBP-like |
cd06268 |
periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the ... |
16-297 |
4.18e-50 |
|
periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily; Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. They are mostly present in archaea and eubacteria, and are primarily involved in scavenging solutes from the environment. ABC-type transporters couple ATP hydrolysis with the uptake and efflux of a wide range of substrates across bacterial membranes, including amino acids, peptides, lipids and sterols, and various drugs. These systems are comprised of transmembrane domains, nucleotide binding domains, and in most bacterial uptake systems, periplasmic binding proteins (PBPs) which transfer the ligand to the extracellular gate of the transmembrane domains. These PBPs bind their substrates selectively and with high affinity. Members of this group include ABC-type Leucine-Isoleucine-Valine-Binding Proteins (LIVBP), which are homologous to the aliphatic amidase transcriptional repressor, AmiC, of Pseudomonas aeruginosa. The uncharacterized periplasmic components of various ABC-type transport systems are included in this group.
Pssm-ID: 380492 [Multi-domain] Cd Length: 298 Bit Score: 169.43 E-value: 4.18e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 16 IALAAPLAGE-SILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMVKN-GISAVIGHACSGASV 93
Cdd:cd06268 2 IGVVVPLTGPyADYGEEILRGVALAVEEINAAGGINGRKLELVIADDQGDPETAVAVARKLVDDdKVLAVVGHYSSSVTL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 94 PASLVYQEDGVLMLSPSSSVPKLTERGLDLVFRLFGRDDRLADAMANHVARKYADKQIAVIHDKRSYGKGLADGFKDGLN 173
Cdd:cd06268 82 AAAPIYQEAGIPLISPGSTAPELTEGGGPYVFRTVPSDAMQAAALADYLAKKLKGKKVAILYDDYDYGKSLADAFKKALK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 174 KRKLREAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAASPAAFWQAAGPAAEG 253
Cdd:cd06268 162 ALGGEIVAEEDFPLGTTDFSAQLTKIKAAGPDVLFLAGYGADAANALKQARELGLKLPILGGDGLYSPELLKLGGEAAEG 241
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 1032077502 254 VVFAS--IAADPTFEGLDAIGKALIEAGRPVTIYGLSAYAAVTVFA 297
Cdd:cd06268 242 VVVAVpwHPDSPDPPKQAFVKAYKKKYGGPPSWRAATAYDATQALA 287
|
|
| PBP1_ABC_HAAT-like |
cd06344 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
13-337 |
2.26e-49 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380567 [Multi-domain] Cd Length: 332 Bit Score: 168.56 E-value: 2.26e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 13 EVVIALAAPLAGEsilGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMVKN-GISAVIGHACSGA 91
Cdd:cd06344 1 DIVIGVAWPFAPD---GDLFLEGVELAVEEINAAGGVLGRKIRLVEYDDEASVDKGLAIAQRFADNpDVVAVIGHRSSYV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 92 SVPASLVYQEDGVLMLSPSSSVPKLTERGLDLVFRLFGRDDRLADAMANHVAR-KYadKQIAVIHDKRSYGKGLADGFKD 170
Cdd:cd06344 78 AIPASIIYERAGLLMLSPGATAPKLTQHGFKYIFRNIPSDEDIARQLARYAARqGY--KRIVIYYDDDSYGKGLANAFEE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 171 GLNKRKLREAVYDALSGDSTAVLPLVRRLKD-RGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAASPAAFWQAAGP 249
Cdd:cd06344 156 EARELGITIVDRRSYSSDEEDFRRLLSKWKAlDFFDAIFLAGSMPEGAEFIKQARELGIKVPIIGGDGLDSPELIEIAGK 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 250 AAEGVVFASI--AADPTFEgldaiGKALIEA-----GRPVTIYGLSAYAAVTVFAQAVRHAKSAEPKAVAAALHA-NEFA 321
Cdd:cd06344 236 AAEGVVVATVfdPDDPRPE-----VRAFVEAfrkkyGREPDVWAAQGYDAVKLLAEAIEKAGSTVPAKIASALRFlENWE 310
|
330
....*....|....*.
gi 1032077502 322 TPLGNVRFSHSGDALG 337
Cdd:cd06344 311 GVTGTYSFDANGDVVG 326
|
|
| PBP1_ABC_HAAT-like |
cd06349 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
15-336 |
6.10e-44 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380572 [Multi-domain] Cd Length: 338 Bit Score: 154.65 E-value: 6.10e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 15 VIALAAPLAGES-ILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMVKN-GISAVIGHACSGAS 92
Cdd:cd06349 1 KIGVSGPLTGDNaEYGQQFKNGVELAVDEINAAGGVNGRKLELVVYDDQGDPKEAVNIAQKFVSDdKVVAVIGDFSSSCS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 93 VPASLVYQEDGVLMLSPSSSVPKLTERGlDLVFRLFGRDDRLADAMANHVARKYADKQIAVIHDKRSYGKGLADGFKDGL 172
Cdd:cd06349 81 MAAAPIYEEAGLVQISPTASHPDFTKGG-DYVFRNSPTQAVEAPFLADYAVKKLGAKKIAIIYLNTDWGVSAADAFKKAA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 173 NKRKLREAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAASPAAFWQAAGPAAE 252
Cdd:cd06349 160 KALGGEIVATEAYLPGTKDFSAQITKIKNANPDAIYLAAYYNDAALIAKQARQLGWDVQIFGSSSLYSPEFIELAGDAAE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 253 GVVFASIaadPTFEGLDAIGKALIEA-----GRPVTIYGLSAYAAVTVFAQAVRHAKSaEPKAVAAALHANEFATPL-GN 326
Cdd:cd06349 240 GVYLSSP---FFPESPDPEVKEFVKAykakyGEDPDDFAARAYDAVNILAEAIEKAGT-DREAIRDALANIKDFSGLtGT 315
|
330
....*....|
gi 1032077502 327 VRFSHSGDAL 336
Cdd:cd06349 316 ITFDENGDVL 325
|
|
| PBP1_ABC_ligand_binding-like |
cd06340 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
14-334 |
3.58e-43 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380563 [Multi-domain] Cd Length: 352 Bit Score: 152.71 E-value: 3.58e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 14 VVIALAAPLAGesiLGQDLKAGAEAAVKAINLGGGLLG---EPLRLELVDDHCDARQGALVATQMV-KNGISAVIGHACS 89
Cdd:cd06340 4 VLYPLSGPLAL---IGQEAKRGAELAVDEINAAGGIKSlggAKIELVVADTQSDPEVAASEAERLItQEGVVAIIGAYSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 90 GASVPASLVYQEDGVLMLSPSSSVPKLTERGLDLVFRLFGRDDRLADAMA-----NHVARKYADKQIAVIHDKRSYGKGL 164
Cdd:cd06340 81 SVTLAASQVAERYGVPFVTASAVADEITERGFKYVFRTAPTASQFAEDAVdflkeLAKKKGKKIKKVAIIYEDSAFGTSV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 165 ADGFKDGLNKRKLREAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAA--SPAA 242
Cdd:cd06340 161 AKGLKKAAKKAGLEVVLDEPYPAGATDLSSEVLKLKAAKPDVVFATSYTNDAILLLRTMKELGFKPKAIIGVGGgySDPE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 243 FWQAAGPAAEGVVFASIAADPTFEGLDAIgKALIEA-----GRPVTIYGLSAYAAVTVFAQAVRHAKSAEPKAV--AAAL 315
Cdd:cd06340 241 FLKALGKDAEGVFSVVPWSPDLAKKKPGA-KEVNERykkkyGEDMTGHAARAYTAAWVLADALERAGSTDPEAIraAAAL 319
|
330 340
....*....|....*....|..
gi 1032077502 316 HANEFA---TPLGNVRFSHSGD 334
Cdd:cd06340 320 TLDIPEgliMPGGGVKFDEKGQ 341
|
|
| PBP1_ABC_ligand_binding-like |
cd19984 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
20-291 |
2.05e-41 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380639 [Multi-domain] Cd Length: 296 Bit Score: 146.59 E-value: 2.05e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 20 APLAGE-SILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQ-MVKNGISAVIGHACSGASVPASL 97
Cdd:cd19984 6 LPLTGDaASYGEDMKNGIELAVEEINAAGGINGKKIELIYEDSKCDPKKAVSAANKlINVDKVKAIIGGVCSSETLAIAP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 98 VYQEDGVLMLSPSSSVPKLTERGlDLVFRLFGRDDRLADAMANHVARKYAdKQIAVIHDKRSYGKGLADGFKDGLNKRKL 177
Cdd:cd19984 86 IAEQNKVVLISPGASSPEITKAG-DYIFRNYPSDAYQGKVLAEFAYNKLY-KKVAILYENNDYGVGLKDVFKKEFEELGG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 178 REAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAASPAAFWQAAGPAAEGVVFA 257
Cdd:cd19984 164 KIVASESFEQGETDFRTQLTKIKAANPDAIFLPGYPKEGGLILKQAKELGIKAPILGSDGFEDPELLEIAGEAAEGVIFT 243
|
250 260 270
....*....|....*....|....*....|....
gi 1032077502 258 SIAADPTFEGLDAIGKALIEAGRPVTIYGLSAYA 291
Cdd:cd19984 244 YPAFDDSSEKKQKFFFYRYKEKYGKEPDIYAALA 277
|
|
| PBP1_ABC_ligand_binding-like |
cd06338 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
14-348 |
7.58e-40 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380561 [Multi-domain] Cd Length: 347 Bit Score: 143.88 E-value: 7.58e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 14 VVIALAAPLAGEsilGQDLKAGAEAAVKAINLGGGLLG--EPLRLELV--DDHCDARQGA-LVATQMVKNGISAVIGHAC 88
Cdd:cd06338 4 ASLSLTGPFAGE---GKAQKRGYELWVEDVNAAGGVKGggKKRPVELVyyDDQSDPATAVrLYEKLITEDKVDLLLGPYS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 89 SGASVPASLVYQEDGVLMLSPSSSVPKLTERGLDLVFRLFGRDDRLADAMANhVARKYAD--KQIAVIHDKRSYGKGLAD 166
Cdd:cd06338 81 SGLTLAAAPVAEKYGIPMIAGGAASDSIFERGYKYVFGVLPPASDYAKGLLD-LLAELGPkpKTVAIVYEDDPFGKEVAE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 167 GFKDGLNKRKLREAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHP-TFFTGEAASPAAFWQ 245
Cdd:cd06338 160 GAREAAKKAGLEVVYDESYPPGTTDFSPLLTKVKAANPDILLVGGYPPDAITLVRQMKELGYNPkAFFLTVGPAFPAFRE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 246 AAGPAAEGVVFASI----AADPTFEGLDAIGKALIE-AGRPVTIYGLSAYAAVTVFAQAVRHAKSAEPKAVAAALHANEF 320
Cdd:cd06338 240 ALGKDAEGVLGPSQwepsLPYKVFPGAKEFVKAYKEkFGEEPSYHAAAAYAAGQVLQQAIEKAGSLDPEKVRDALASLDF 319
|
330 340
....*....|....*....|....*...
gi 1032077502 321 ATPLGNVRFSHSGDALGIRYQISRWSNG 348
Cdd:cd06338 320 DTVYGPIKFDETGLQIGKPMVVVQWQGG 347
|
|
| PBP1_ABC_LivK_ligand_binding-like |
cd06347 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
15-337 |
1.06e-39 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380570 [Multi-domain] Cd Length: 334 Bit Score: 143.07 E-value: 1.06e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 15 VIALAAPLAGE-SILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMV-KNGISAVIGHACSGAS 92
Cdd:cd06347 1 KIGVIGPLTGEaAAYGQPALNGAELAVDEINAAGGILGKKIELIVYDNKSDPTEAANAAQKLIdEDKVVAIIGPVTSSIA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 93 VPASLVYQEDGVLMLSPSSSVPKLTErGLDLVFRL-FGrDDRLADAMANHVARKYADKQIAVIHDKRS-YGKGLADGFKD 170
Cdd:cd06347 81 LAAAPIAQKAKIPMITPSATNPLVTK-GGDYIFRAcFT-DPFQGAALAKFAYEELGAKKAAVLYDVSSdYSKGLAKAFKE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 171 GLNKRKLREAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAASPAAFWQAAGPA 250
Cdd:cd06347 159 AFEKLGGEIVAEETYTSGDTDFSAQLTKIKAANPDVIFLPGYYEEAALIIKQARELGITAPILGGDGWDSPELLELGGDA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 251 AEGVVFAS-IAADPTfeglDAIGKALIEA-----GRPVTIYGLSAYAAVTVFAQAVRHAKSAEPKAVAAALHAN-EFATP 323
Cdd:cd06347 239 VEGVYFTThFSPDDP----SPEVQEFVKAykakyGEPPNAFAALGYDAVMLLADAIKRAGSTDPEAIRDALAKTkDFEGV 314
|
330
....*....|....
gi 1032077502 324 LGNVRFSHSGDALG 337
Cdd:cd06347 315 TGTITFDPNGNPIK 328
|
|
| PBP1_ABC_ligand_binding-like |
cd06335 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
15-315 |
1.97e-39 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380558 [Multi-domain] Cd Length: 348 Bit Score: 142.75 E-value: 1.97e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 15 VIALAAPLAGESI-LGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMV-KNGISAVIGHACSGAS 92
Cdd:cd06335 1 KIGVIGPLTGPSAeLGESARRGVELAVEEINAAGGILGRKIELVERDDEANPTKAVQNAQELIdKEKVVAIIGPTNSGVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 93 VPASLVYQEDGVLMLSPSSSVPKLT---ERGLDLVFRLFGRDDRLADAMANHVARKYADKqIAVIHDKRSYGKGLADGFK 169
Cdd:cd06335 81 LATIPILQEAKIPLIIPVATGTAITkppAKPRNYIFRVAASDTLQADFLVDYAVKKGFKK-IAILHDTTGYGQGGLKDVE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 170 DGLNKRKLrEAVYDAL--SGDsTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAASPAAFWQAA 247
Cdd:cd06335 160 AALKKRGI-TPVATESfkIGD-TDMTPQLLKAKDAGADVILVYGLGPDLAQILKAMEKLGWKVPLVGSWGLSMPNFIELA 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1032077502 248 GPAAEGVVFASIAadpTFEGLDAIGKALIEAGRPvtIYGL----------SAYAAVTVFAQAVRHAKSAEPKAVAAAL 315
Cdd:cd06335 238 GPLAEGTIMTQTF---IEDYLTPRAKKFIDAYKK--KYGTdripspvsaaQGYDAVYLLAAAIKQAGSTDGKKIRAAL 310
|
|
| PBP1_ABC_ligand_binding-like |
cd19980 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
16-342 |
2.77e-39 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380635 [Multi-domain] Cd Length: 334 Bit Score: 141.98 E-value: 2.77e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 16 IALAAPLAGES-ILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMV-KNGISAVIGHACSGASV 93
Cdd:cd19980 2 IGVIAPLSGPVaALGQQVLNGAKLAVEEINAKGGVLGRKLELVVEDDKCPPAEGVAAAKKLItDDKVPAIIGAWCSSVTL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 94 PASLVYQEDGVLMLSPSSSVPKLTERGLDLVFRLFGRDDRLADAMANHVARKYADKQIAVIHDKRSYGKGLADGFKDGLN 173
Cdd:cd19980 82 AVMPVAERAKVPLVVEISSAPKITEGGNPYVFRLNPTNSMLAKAFAKYLADKGKPKKVAFLAENDDYGRGAAEAFKKALK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 174 KRKLREAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAASPAAFWQAAGPAAEG 253
Cdd:cd19980 162 AKGVKVVATEYFDQGQTDFTTQLTKLKAANPDAIFVVAETEDGALILKQARELGLKQQLVGTGGTTSPDLIKLAGDAAEG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 254 VVFASIAAdPTFEglDAIGKALIEA-----GRPVTIYGLSAYAAVTVFAQAVRHAKSAEPKAV-AAALHANEFATPLGNV 327
Cdd:cd19980 242 VYGASIYA-PTAD--NPANKAFVAAykkkyGEPPDKFAALGYDAVMVIAEAIKKAGSTDPEKIrAAALKKVDYKGPGGTI 318
|
330
....*....|....*
gi 1032077502 328 RFSHSGDALGIRYQI 342
Cdd:cd19980 319 KFDEKGQAHKNVVLV 333
|
|
| PBP1_ABC_ligand_binding-like |
cd06346 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
28-299 |
2.02e-34 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380569 [Multi-domain] Cd Length: 314 Bit Score: 128.45 E-value: 2.02e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 28 LGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMV-KNGISAVIGHACSGASVPASLVYQEDGVLM 106
Cdd:cd06346 15 LGPPMLAAAELAVEEINAAGGVLGKKVELVVEDSQTDPTAAVDAARKLVdVEGVPAIVGAASSGVTLAVASVAVPNGVVQ 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 107 LSPSSSVPKLTE-RGLDLVFRLFGRDDRLADAMANhVARKYADKQIAVIHDKRSYGKGLADGFKDGLNKRK---LREAVY 182
Cdd:cd06346 95 ISPSSTSPALTTlEDKGYVFRTAPSDALQGVVLAQ-LAAERGFKKVAVIYVNNDYGQGLADAFKKAFEALGgtvTASVPY 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 183 DALSGDSTAVlplVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPT--FFTGEAASPAAFWQAAGPAAEGVVFASIA 260
Cdd:cd06346 174 EPGQTSYRAE---LAQAAAGGPDALVLIGYPEDGATILREALELGLDFTpwIGTDGLKSDDLVEAAGAEALEGMLGTAPG 250
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 1032077502 261 ADPTfEGLDAIGKALIEA-GRPVTIYGLSAYAAVTVFAQA 299
Cdd:cd06346 251 SPGS-PAYEAFAAAYKAEyGDDPGPFAANAYDAVMLLALA 289
|
|
| Peripla_BP_6 |
pfam13458 |
Periplasmic binding protein; This family includes a diverse range of periplasmic binding ... |
13-348 |
6.05e-32 |
|
Periplasmic binding protein; This family includes a diverse range of periplasmic binding proteins.
Pssm-ID: 433225 [Multi-domain] Cd Length: 342 Bit Score: 122.77 E-value: 6.05e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 13 EVVIALAAPLAGE-SILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMV-KNGISAVIGHACSG 90
Cdd:pfam13458 1 PIKIGVLTPLSGPyASSGKSSRAGARAAIEEINAAGGVNGRKIELVVADDQGDPDVAAAAARRLVdQDGVDAIVGGVSSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 91 ASVPASLVYQEDGVLMLSPSSSVPKLTERGldlVFRLFGRDDRLADAMANHVARKYADKQIAVIHDKRSYGKGLADGFKD 170
Cdd:pfam13458 81 VALAVAEVLAKKGVPVIGPAALTGEKCSPY---VFSLGPTYSAQATALGRYLAKELGGKKVALIGADYAFGRALAAAAKA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 171 GLNKRKLREAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFT--GEAASPAAFWQAAG 248
Cdd:pfam13458 158 AAKAAGGEVVGEVRYPLGTTDFSSQVLQIKASGADAVLLANAGADTVNLLKQAREAGLDAKGIKlvGLGGDEPDLKALGG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 249 PAAEGVVFA-SIAADPTFEGLDAIGKALIEA--GRPVTIYGLSAYAAVTVFAQAVRHAKSAEPKAVAAALHANEFATPLG 325
Cdd:pfam13458 238 DAAEGVYATvPFFPDLDNPATRAFVAAFAAKygEAPPTQFAAGGYIAADLLLAALEAAGSPTREAVIAALRALPYDGPFG 317
|
330 340
....*....|....*....|...
gi 1032077502 326 NVRFSHSGDALGIRYQISRWSNG 348
Cdd:pfam13458 318 PVGFRAEDHQAVHCMYLVQVKAD 340
|
|
| PBP1_ABC_ligand_binding-like |
cd06345 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
15-330 |
6.38e-29 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380568 [Multi-domain] Cd Length: 356 Bit Score: 114.67 E-value: 6.38e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 15 VIALAAPLagESILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMV-KNGISAVIGHACSGASV 93
Cdd:cd06345 1 KIGVLGPL--SAPAGEAMERGAELAVEEINAAGGILGRKVELVVADTQGKPEDGVAAAERLItEDKVDAIVGGFRSEVVL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 94 PASLVYQEDGVLMLSPSSSVPKLTER------GLDLVFRLFGRDDRLA----DAMANHVARKYADKQIAVIHDKRSYGKG 163
Cdd:cd06345 79 AAMEVAAEYKVPFIVTGAASPAITKKvkkdyeKYKYVFRVGPNNSYLGatvaEFLKDLLVEKLGFKKVAILAEDAAWGRG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 164 LADGFKDGLNKRKLREAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFT--GEAASPA 241
Cdd:cd06345 159 IAEALKKLLPEAGLEVVGVERFPTGTTDFTPILSKIKASGADVIVTIFSGPGGILLVKQWAELGVPAPLVGinVPAQDPE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 242 aFWQAAGPAAEGVVFASIAADPTfeGLDAIGKALIEA-----GRPVTIYGLSAYAAVTVFAQAVRHAKSAEPKAVAAALH 316
Cdd:cd06345 239 -FWENTGGAGEYEITLAFAAPKA--KVTPKTKPFVDAykkkyGEAPNYTAYTAYDAIYILAEAIERAGSTDPDALVKALE 315
|
330
....*....|....
gi 1032077502 317 ANEFATPLGNVRFS 330
Cdd:cd06345 316 KTDYEGVRGRIKFD 329
|
|
| PBP1_ABC_HAAT-like |
cd19988 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
15-256 |
7.01e-29 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380643 [Multi-domain] Cd Length: 302 Bit Score: 113.53 E-value: 7.01e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 15 VIALAAPLAG-ESILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMV-KNGISAVIGHACSGAS 92
Cdd:cd19988 1 KIGVFGPLSGdAAPYGQAMLQGAELAVEEINAAGGILGIPIELVVEDDEGLPAASVSAAKKLIyQDKVWAIIGSINSSCT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 93 VPASLVYQEDGVLMLSPSSSVPKLTERGLDLVFRLFGRDDRLADAMANHVARKYADKQIAVIHDKRSYGKGLADGFKDGL 172
Cdd:cd19988 81 LAAIRVALKAGVPQINPGSSAPTITESGNPWVFRCTPDDRQQAYALVDYAFEKLKVTKIAVLYVNDDYGRGGIDAFKDAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 173 NKRKLREAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAASPAAFWQAAGPAAE 252
Cdd:cd19988 161 KKYGIEVVVEESYNRGDKDFSPQLEKIKDSGAQAIVMWGQYTEGALIAKQARELGLKQPLFGSDGLVTPKFIELAGDAAE 240
|
....
gi 1032077502 253 GVVF 256
Cdd:cd19988 241 GAIA 244
|
|
| PBP1_ABC_ligand_binding-like |
cd06343 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
13-348 |
8.04e-28 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however its ligand specificity has not been determined experimentally.
Pssm-ID: 380566 [Multi-domain] Cd Length: 355 Bit Score: 111.51 E-value: 8.04e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 13 EVVIALAAPLAGE-SILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMV-KNGISAVIGHACSg 90
Cdd:cd06343 6 EIKIGTSLPLSGPaAAYGKPVRAGAAAYFDEVNAAGGINGRKIELIVEDDGYDPARAVAAVRKLVeQDKVFAIVGGLGT- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 91 ASVPASLVYQED-GVLMLSPSSSVPKLTERGLDLVFRLFGRDDRLADAMANHVARKYADKQIAVIHDKRSYGKGLADGFK 169
Cdd:cd06343 85 PTNLAVRPYLNEaGVPQLFPATGASALSPPPKPYTFGVQPSYEDEGRILADYIVETLPAAKVAVLYQNDDFGKDGLEGLK 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 170 DGLNKRKLR---EAVYDALSGD-STAVLplvrRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFF-TGEAASPAAFW 244
Cdd:cd06343 165 EALKAYGLEvvaEETYEPGDTDfSSQVL----KLKAAGADVVVLGTLPKEAAAALKEAAKLGWKPTFLgSSVSADPTTLA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 245 QAAGPAAEGVVFASIAADPTFEGLDAIgKALIEA------GRPVTIYGLSAYAAVTVFAQAVRHA-KSAEPKAVAAALHA 317
Cdd:cd06343 241 KAGGDAAEGVYSASYLKDPTDADDPAV-KEFREAykkyfpDDPPNAYALYGYAAAQVFVEALKRAgKDLTREGLIKALES 319
|
330 340 350
....*....|....*....|....*....|....*
gi 1032077502 318 --NEFATPLG-NVRFShSGDALGIR-YQISRWSNG 348
Cdd:cd06343 320 lkDFDDGGPGpPVTFS-PDDHRGIEsMYLVQVDGG 353
|
|
| PBP1_ABC_HAAT-like |
cd19981 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
16-301 |
7.36e-27 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380636 [Multi-domain] Cd Length: 297 Bit Score: 107.76 E-value: 7.36e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 16 IALAAPLAG-ESILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMV-KNGISAVIGHACSGASV 93
Cdd:cd19981 2 IGFFAPLTGpAAADGKSALHGAELAVEQINAAGGINGKKVELVVYDDQASPKQAVNIAQKLIeQDKVVAVVSGSYSGPTR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 94 PASLVYQEDGVLMLSPSSSVPKLTERGlDLVFRLFGRDDRLADAMANHVARKYADKQIAVIHDKRSYGKGLADGFKDGLN 173
Cdd:cd19981 82 AAAPIFQEAKVPMVSAYAVHPDITKAG-DYVFRVAFLGPVQGRAGAEYAVKDLGAKKVAILTIDNDFGKSLAAGFKEEAK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 174 KRKLREAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAASPAAFWQAAGPAAEG 253
Cdd:cd19981 161 KLGAEIVSEYAYALGDRDFRPILTKIKSANPDAIYASGYYAEAAPIVKQARELGIKVPIIGQEGYDSPKFIEIAGSAAEG 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1032077502 254 VVFA-SIAADPTfeglDAIGKALIE-----AGRPVTIYGLSAYAAVTVFAQAVR 301
Cdd:cd19981 241 VIITtSLNRDSD----RPITQKFIKeyrkrYGIDPDMVAASTYDAVMVLAGEVQ 290
|
|
| PBP1_ABC_transporter_GPCR_C-like |
cd04509 |
Family C of G-protein coupled receptors and their close homologs, the type 1 ... |
35-255 |
8.41e-24 |
|
Family C of G-protein coupled receptors and their close homologs, the type 1 periplasmic-binding proteins of ATP-binding cassette transporter-like systems; This CD includes members of the family C of G-protein coupled receptors and their close homologs, the type 1 periplasmic-binding proteins of ATP-binding cassette transporter-like systems. The family C GPCR includes glutamate/glycine-gated ion channels such as the NMDA receptor, G-protein-coupled receptors, metabotropic glutamate, GABA-B, calcium sensing, pheromone receptors, and atrial natriuretic peptide-guanylate cyclase receptors. The glutamate receptors that form cation-selective ion channels, iGluR, can be classified into three different subgroups according to their binding-affinity for the agonists NMDA (N-methyl-D-asparate), AMPA (alpha-amino-3-dihydro-5-methyl-3-oxo-4-isoxazolepropionic acid), and kainate. L-glutamate is a major neurotransmitter in the brain of vertebrates and acts through either mGluRs or iGluRs. mGluRs subunits possess seven transmembrane segments and a large N-terminal extracellular domain. ABC-type leucine-isoleucine-valine binding protein (LIVBP) is a bacterial periplasmic binding protein that has homology with the amino-terminal domain of the glutamate-receptor ion channels (iGluRs). The extracellular regions of iGluRs are made of two PBP-like domains in tandem, a LIVBP-like domain that constitutes the N terminus (included in this model) followed by a domain related to lysine-arginine-ornithine-binding protein (LAOBP) that belongs to the type 2 periplasmic binding fold protein superfamily. The uncharacterized periplasmic components of various ABC-type transport systems are also included in this family.
Pssm-ID: 380490 Cd Length: 306 Bit Score: 99.69 E-value: 8.41e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 35 GAEAAVKAINLGGGLLGE-PLRLELVDDHCDARQGALVATQMV-----------------------KNGISAVIGHACSG 90
Cdd:cd04509 32 AMEQALDDINADPNLLPNnTLGIVIYDDCCDPKQALEQSNKFVndliqkdtsdvrctngeppvfvkPEGIKGVIGHLCSS 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 91 ASVPASLVYQEDGVLMLSPSSSVPKLT-ERGLDLVFRLFGRDDRLADAMANHVARkYADKQIAVIHDKRSYGKGLADGFK 169
Cdd:cd04509 112 VTIPVSNILELFGIPQITYAATAPELSdDRGYQLFLRVVPLDSDQAPAMADIVKE-KVWQYVSIVHDEGQYGEGGARAFQ 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 170 DGLNKRKLREAVYDAL-SGDSTAVLP-LVRRLKDR-GVDVVFFGGYFDDMVQLVRVS--AEQDYHPTFFTGEA-ASPAAF 243
Cdd:cd04509 191 DGLKKGGLCIAFSDGItAGEKTKDFDrLVARLKKEnNIRFVVYFGYHPEMGQILRAArrAGLVGKFQFMGSDGwANVSLS 270
|
250
....*....|..
gi 1032077502 244 WQAAGPAAEGVV 255
Cdd:cd04509 271 LNIAEESAEGLI 282
|
|
| PBP1_ABC_ligand_binding-like |
cd19982 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
21-298 |
5.66e-23 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380637 [Multi-domain] Cd Length: 302 Bit Score: 97.35 E-value: 5.66e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 21 PLAG-ESILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMV-KNGISAVIGHACSGASVPASLV 98
Cdd:cd19982 7 SLTGpFAPFGEMFKNGYEMALEEINAAGGIKGKKLELVIEDDQSKPQTALAAAEKLVsQDKVPLIVGGYSSGITLPVAAV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 99 YQEDGVLMLSPSSSVPKLTERGLDLVFRLfgrddrladamaNHVARKYAD------------KQIAVIHDKRSYGKGLAD 166
Cdd:cd19982 87 AERQKIPLLVPTAADDDITKPGYKYVFRL------------NPPASIYAKalfdffkelvkpKTIAILYENTAFGTSVAK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 167 GFKDGLNKRKLREAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAA--SPAAFW 244
Cdd:cd19982 155 AARRFAKKRGIEVVADESYDKGATDFKPLLNKVKAANPDVVYMVSYLNDAILLMRQAKELGLNPKLFAGGGAgfTIPEFL 234
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1032077502 245 QAAGPAAEGVVFA-SIAADPTFEGLDAIGKALIE-AGRPVTIYGLSAYAAVTVFAQ 298
Cdd:cd19982 235 KQAGPLAEYVVTAtLWSPDVKYPGAKEFYEKYKAkYGVEPSYHEAEAYAALYVAAN 290
|
|
| PBP1_ABC_HAAT-like |
cd19986 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
16-297 |
1.89e-22 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380641 [Multi-domain] Cd Length: 297 Bit Score: 95.77 E-value: 1.89e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 16 IALAAPLAGE-SILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDArQGALVATQ--MVKNGISAVIGHACSGAS 92
Cdd:cd19986 2 IGVVAPLTGPaALNGEYQKNGAQLALEEINAAGGVLGRPLELVVEDDQGTN-TGAVNAVNklISDDKVVAVIGPHYSTQV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 93 VPASLVYQEDGVLMLSPSSSvPKLTERGLDLVFRLFGRDDRLADAMANHVARKYADKQIAVIHDKRSYGKGLADGFKDGL 172
Cdd:cd19986 81 LAVSPLVKEAKIPVITGGTS-PKLTEQGNPYMFRIRPSDSVSAKALAKYAVEELGAKKIAILYDNDDFGTGGADVVTAAL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 173 NKRKLREAV---YDALSGDSTAVLplvRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAASPAAFWQAAGP 249
Cdd:cd19986 160 KALGLEPVAvesYNTGDKDFTAQL---LKLKNSGADVIIAWGHDAEAALIARQIRQLGLDVPVIGSSSFATPTVLLLAGE 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 1032077502 250 AAEGVVfasIAADPTFEGLDAIGKALIEA-----GRPVTIYGLSAYAAVTVFA 297
Cdd:cd19986 237 ALEGIY---SVTDFVPSDPDPKVQAFVKKykakyGEDPDLYSAWYYDAMYLLA 286
|
|
| PBP1_ABC_RPA1789-like |
cd06333 |
type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, ... |
14-333 |
2.49e-22 |
|
type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, RPA1791-1793), involved in active transport of lignin-derived aromatic substrates, and its close homologs; This group includes RPA1789 (CouP) from Rhodopseudomonas palustris and its close homologs in other bacteria. RPA1789 (CouP) is the periplasmic binding-protein component of an ABC system (CouPSTU; RPA1789, RPA1791-1793) that is involved in the active transport of lignin-derived aromatic substrates. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380556 [Multi-domain] Cd Length: 342 Bit Score: 96.08 E-value: 2.49e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 14 VVIALAAPLAGesiLGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMVKN-GISAVIGHACSGAS 92
Cdd:cd06333 4 AILSLTGPAAS---LGIPERNAVELLVEQINAAGGINGRKLELIVYDDESDPTKAVTNARKLIEEdKVDAIIGPSTTGES 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 93 VPASLVYQEDGVLMLSPSSSVPkLTERGLDLVFRLFGRDDRLADAMANHVARKYAdKQIAVIHDKRSYGKGLADGFKDGL 172
Cdd:cd06333 81 LAVAPIAEEAKVPLISLAGAAA-IVEPVRKWVFKTPQSDSLVAEAILDYMKKKGI-KKVALLGDSDAYGQSGRAALKKLA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 173 NKRKL---REAVYDAlsGDsTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYH-PTFFTGEAASPaAFWQAAG 248
Cdd:cd06333 159 PEYGIeivADERFAR--TD-TDMTAQLTKIRAAKPDAVLVWASGPPAALVAKNLRQLGYKgPIYQSHGAANQ-DFIKLAG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 249 PAAEGVVFAS---------IAADPTFEGLDAIGKALIEA-GRPVTIYGLSAYAAVTVFAQAVRHAKSAEPKAVAAAL-HA 317
Cdd:cd06333 235 KAAEGVILPAgkllvadqlPDSDPQKKVLLEFVKAYEAKyGEGPSTFAGHAYDALLLLVEAIEPAGGTDRAALRDALeNT 314
|
330
....*....|....*....
gi 1032077502 318 NEFATPLGNVRFS---HSG 333
Cdd:cd06333 315 KGLVGVTGVYNFSptdHNG 333
|
|
| PBP1_ABC_HAAT-like |
cd19985 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
16-169 |
8.63e-21 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380640 [Multi-domain] Cd Length: 321 Bit Score: 91.57 E-value: 8.63e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 16 IALAAPLAGES-ILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMVKNGISAVIGHACSGASVP 94
Cdd:cd19985 2 IAVVGPMSGKSaSKGKSMLRGAELYIDQINAAGGINGKKVKLDVFDDQNDPDAARKAAQIIVSDKALAVIGHYYSSASIA 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1032077502 95 ASLVYQEDGVLMLSPSSSVPKLTERGlDLVFRLFGRDDRLADAMANHVARKYADKQIAVIHDKRSYGKGLADGFK 169
Cdd:cd19985 82 AGKIYKKAGIPAITPSATADAVTRDN-PWYFRVIFNDSLQGRFLANYAKKVLKKDKVSIIYEEDSYGKSLASVFE 155
|
|
| ANF_receptor |
pfam01094 |
Receptor family ligand binding region; This family includes extracellular ligand binding ... |
33-342 |
1.03e-19 |
|
Receptor family ligand binding region; This family includes extracellular ligand binding domains of a wide range of receptors. This family also includes the bacterial amino acid binding proteins of known structure.
Pssm-ID: 460062 [Multi-domain] Cd Length: 347 Bit Score: 88.98 E-value: 1.03e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 33 KAGAEAAVKAINLGGGLLGEP-LRLELVDDHCDARQGALVATQMVKNGISAVIGHACSGASVPASLVYQEDGVLMLSPSS 111
Cdd:pfam01094 3 LLAVRLAVEDINADPGLLPGTkLEYIILDTCCDPSLALAAALDLLKGEVVAIIGPSCSSVASAVASLANEWKVPLISYGS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 112 SVPKLTERG-LDLVFRLFGRDDRLADAMAnHVARKYADKQIAVIHDKRSYGKGLADGFKDGLNKRKLREAVYDAL--SGD 188
Cdd:pfam01094 83 TSPALSDLNrYPTFLRTTPSDTSQADAIV-DILKHFGWKRVALIYSDDDYGESGLQALEDALRERGIRVAYKAVIppAQD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 189 STAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQD-----YHPTFFTGEAASPAAFWQAAGPAAEGVVFASIaADP 263
Cdd:pfam01094 162 DDEIARKLLKEVKSRARVIVVCCSSETARRLLKAARELGmmgegYVWIATDGLTTSLVILNPSTLEAAGGVLGFRL-HPP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 264 TFEGL-DAIGKALIEAGRPVT-------IYGLSAYAAVTVFAQAVRHAKSAEPKAVAAALHAN--------------EFA 321
Cdd:pfam01094 241 DSPEFsEFFWEKLSDEKELYEnlgglpvSYGALAYDAVYLLAHALHNLLRDDKPGRACGALGPwnggqkllrylknvNFT 320
|
330 340
....*....|....*....|.
gi 1032077502 322 TPLGNVRFSHSGDALGIRYQI 342
Cdd:pfam01094 321 GLTGNVQFDENGDRINPDYDI 341
|
|
| PBP1_ABC_HAAT-like |
cd06348 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
16-337 |
1.41e-19 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380571 [Multi-domain] Cd Length: 342 Bit Score: 88.44 E-value: 1.41e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 16 IALAAPLAGESIL-GQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMV-KNGISAVIGHACSGASV 93
Cdd:cd06348 2 IGVALSLTGPGALyGQSQKNGAQLAVEEINAAGGVGGVKIELIVEDTAGDPEQAINAFQKLInQDKVLAILGPTLSSEAF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 94 PASLVYQEDGVLMLSPSSSVPKLTERGlDLVFRLFGRDDRLADAMANHVARKYADKQIAVIHD-KRSYGKGLADGFKDGL 172
Cdd:cd06348 82 AADPIAQQAKVPVVGISNTAPGITDIG-PYIFRNSLPEDKVIPPTVKAAKKKYGIKKVAVLYDqDDAFTVSGTKVFPAAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 173 NKRKLREAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAASPAAFWQAAGPAAE 252
Cdd:cd06348 161 KKNGVEVLDTETFQTGDTDFSAQLTKIKALNPDAIVISALAQEGALIVKQARELGLKGPIVGGNGFNSPDLIKLAGKAAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 253 GVVFASI--AADPTFEGLDAIGKALIEAGRPVTIYGLSAYAAVTVFAQAVRHAKS-AEPKAVAAAL----HANEFATPLG 325
Cdd:cd06348 241 GVIVGSAwsPDNPDPKNQAFVAAYKEKYGKEPDQFAAQAYDAAYILAEAIKKAGStTDRADLRDALarilIAKDFEGPLG 320
|
330
....*....|..
gi 1032077502 326 NVRFSHSGDALG 337
Cdd:cd06348 321 PFSFDADRDGIQ 332
|
|
| PBP1_As_SBP-like |
cd06330 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
16-329 |
4.76e-19 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea that is predicted to be involved in the efflux of toxic compounds. Members of this subgroup include proteins from Herminiimonas arsenicoxydans, which is resistant to arsenic (As) and various heavy metals such as cadmium and zinc. Moreover, they show significant sequence similarity to the cluster of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa.
Pssm-ID: 380553 [Multi-domain] Cd Length: 342 Bit Score: 86.85 E-value: 4.76e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 16 IALAAPLAGE-SILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMV-KNGISAVIGHACSGASV 93
Cdd:cd06330 2 IGVITPLSGAaAVYGEPARNGAELAVEEINAAGGILGRKIELVVRDDKGKPDEAVRAARELVlQEGVDFLIGTISSGVAL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 94 PASLVYQEDGVLMLSPSSSVPKLT-ERGLDLVFRLFGRDDRLADAMANHVARKYAD-KQIAVIHDKRSYGKGLADGFKDG 171
Cdd:cd06330 82 AVAPVAEELKVLFIATDAATDRLTeENFNPYVFRTSPNTYMDAVAAALYAAKKPPDvKRWAGIGPDYEYGRDSWAAFKAA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 172 LNKRKLREAVYDAL-----SGDSTAVlplVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYH--PTFFTGEAASPAAFW 244
Cdd:cd06330 162 LKKLKPDVEVVGELwpklgATDYTAY---ITALLAAKPDGVFSSLWGGDLVTFVKQAKPYGLFdkTKVVSGLGGGSEVLQ 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 245 QAAGPAAEGVVfasIAADPTFEGLD-AIGKALIEA-----GRPVTIYGLSAYAAVTVFAQAVRHAKSAEPKAVAAALHAN 318
Cdd:cd06330 239 ALGKEMPEGLI---GGGRYPFGWPDtPLNKAFVEAyrakyGEYPTYWAYEAYAAVMALKAAIEKAGSTDTDKVIAALEGL 315
|
330
....*....|.
gi 1032077502 319 EFATPLGNVRF 329
Cdd:cd06330 316 TFDTPGGKITI 326
|
|
| PBP1_ABC_ligand_binding-like |
cd06326 |
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to ... |
14-316 |
1.13e-18 |
|
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.
Pssm-ID: 380549 [Multi-domain] Cd Length: 339 Bit Score: 85.67 E-value: 1.13e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 14 VVIALAAPLAGESI-LGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMVKN-GISAVIGHAcSGA 91
Cdd:cd06326 1 IVIGQSAPLSGPLAeLGREYLAGAKAYFDQVNAAGGINGRKIRLVTLDDGYDPARTVENTRQLIEQdKVVALFGYV-GTA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 92 SVPASL-VYQEDGVLMLSPSSSVPKLTERGLDLVFRLFGRDDRLADAMANHVARKYAdKQIAVIHDKRSYGKGLADGFKD 170
Cdd:cd06326 80 NVEAVLpLLEEAGVPLVGPLTGADSLREPGNPYVFHVRASYADEVEKIVRHLATLGL-KRIAVVYQDDPFGKEGLAAAEA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 171 GLNKRKLREAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAASPAAFWQAAGPA 250
Cdd:cd06326 159 ALAARGLEPVATAAVARNAADVAAAAAALAAAKPQAVVLIAAGKAAAAFIKALRAAGGAAQFYGLSVVGAAALAKALGDA 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1032077502 251 AEGVVFASIAADPTFEGLDAIG---KALIEAG-RPVTIYGLSAYAAVTVFAQAVRHAKSAEPKA-VAAALH 316
Cdd:cd06326 239 ARGVVVSQVVPNPWSTTLPLVReyqAAMKAAGpKEPSYASLEGYIAARVLVEALRRAGRNPTREsLVAALE 309
|
|
| PBP1_ABC_ligand_binding-like |
cd19978 |
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to ... |
14-305 |
2.33e-18 |
|
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.
Pssm-ID: 380633 [Multi-domain] Cd Length: 341 Bit Score: 84.93 E-value: 2.33e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 14 VVIALAAPLAGES-ILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQgALVATQ--MVKNGISAVIGH---A 87
Cdd:cd19978 1 IRLGMSAALSGPAaELGNEMKRGIEAAFNEVNAQGGVNGRKIKLIALDDGYEPDR-TVKNTKklIEEDKVFALIGYvgtP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 88 CSGASVPaslVYQEDGVLMLSPSSSVPKLTERGLDLVFRLFGRDDRLADAMANHVARKYADKQIAVIHDKRSYGKGLADG 167
Cdd:cd19978 80 TALAALP---LANEKKIPLFGPFTGAEFLRTPFLPYVFNLRASYADETEALVDYLVKTLGPKRIAIFYQNDAFGLAGLEG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 168 FKDGLNKRKLR---EAVYDAlsgDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAASPAAFW 244
Cdd:cd19978 157 AKKALKKRGLTpvaEGSYTR---NTLDVEEALAKILKAKPEAIILVGTYAPAAEFIRLARAAGLNPLFANVSFVGSEALA 233
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1032077502 245 QAAGPAAEGVVFASIAADPTFEGL-------DAIGKALIEAgrPVTIYGLSAYAAVTVFAQAVRHAKS 305
Cdd:cd19978 234 LELGDYGEGVIVSQVVPDPNDSSLpivkeyrEAMKKYGPNA--PPDFVSLEGYLAARLLVEALKKAGP 299
|
|
| PBP1_ABC_HAAT-like |
cd19983 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
16-297 |
4.42e-18 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380638 [Multi-domain] Cd Length: 303 Bit Score: 83.40 E-value: 4.42e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 16 IALAAPLAGE-SILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMVKNGISAVIGHACSGASVP 94
Cdd:cd19983 2 IGFVGGLTGRySDLGVQGRNGAQLAVEEINAAGGINGRPVELIIRDDQQDPEAAKAADRELIAGGVVAIIGHMTSAMTVA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 95 ASLVYQEDGVLMLSPSSSVPKLTERGlDLVFRLFGRDDRLADAMANHVARKYADKQIAVIHDK--RSYGKGLADGFKDGL 172
Cdd:cd19983 82 VLPVINEAKVLMISPTVSTPELSGKD-DYFFRVTPTTRESAQALARYAYNRGGLRRVAVIYDLsnRAYSESWLDNFRSEF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 173 NKRK---LREAVYDalSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAASPAAFWQAAGP 249
Cdd:cd19983 161 EALGgriVAEIPFS--SGADVDFSDLARRLLASKPDGLLLVASAVDTAMLAQQIRKLGSKIPLFSSAWAATEELLELGGK 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1032077502 250 AAEGVVFA-SIAADPTFEGLDAIGKALIEA-GRPVTIYGLSAYAAVTVFA 297
Cdd:cd19983 239 AVEGMLFSqAYDRNSSNPRYLAFKEAYEERfGREPSFAAAYAYEAAMVLA 288
|
|
| PBP1_ABC_ligand_binding-like |
cd06336 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
15-315 |
2.25e-17 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380559 [Multi-domain] Cd Length: 345 Bit Score: 81.90 E-value: 2.25e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 15 VIALAAPLAGESIL-GQDLKAGAEAAVKAINLG--GGLLGEPLRLELV--DDHCDARQGALVATQMV-KNGISAVIGHAC 88
Cdd:cd06336 1 KIGFLGPLSGPAAAwGLPMLRGLELAADEINAAggIKVGGKKYKVEVVsyDDKYTPAEAVAAARRLVsQDGVKFIFGPGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 89 SGASVPASLVYQEDGVLMLSPSSSVPkLTERGLDLVFRLFGRDDRLADAMANHVARKYADKQIAVIHDKRSYGKGLADGF 168
Cdd:cd06336 81 SAIAAAVQPVTERNKVLLLTAAFSDP-ILGPDNPLLFRIPPTPYEYAPPFIKWLKKNGPIKTVALIAPNDATGKDWAAAF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 169 KDGLNKRKLrEAVYDAL-SGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMV-QLVRVSAEQDYHPTFFTGEAASPAAFWQA 246
Cdd:cd06336 160 VAAWKAAGG-EVVAEEFyDRGTTDFYPVLTKILALKPDALDLGGSSPGPAgLIIKQARELGFKGPFVSEGGAKADEILKE 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1032077502 247 AGP-AAEGVVFasIAADPTFEGLDAIGKALIEA-----GRPVTIYGLSAYAAVTVFAQAVRHAKSAEPKAVAAAL 315
Cdd:cd06336 239 VGGeAAEGFIG--VLPADDDPIASPGAKAFVERykkkyGEPPNSESALFYDAAYILVKAMEKAGTVDDTKKIRAA 311
|
|
| PBP1_AmiC-like |
cd06331 |
type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system ... |
16-331 |
4.18e-13 |
|
type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF); This group includes the type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF), found in bacteria and Archaea. AmiC controls expression of the amidase operon by a ligand-triggered conformational switch. In the absence of ligand or presence of butyramide (repressor), AmiC (the ligand sensor and negative regulator) adopts an open conformation and inhibits the transcription antitermination function of AmiR by direct protein-protein interaction. In the presence of inducing ligands such as acetamide, AmiC adopts a closed conformation which disrupts a silencing AmiC-AmiR complex and the expression of amidase and other genes of the operon is induced. FmdDEF is predicted to be an ATP-dependent transporter and closely resembles the periplasmic binding protein and the two transmembrane proteins present in various hydrophobic amino acid-binding transport systems.
Pssm-ID: 380554 [Multi-domain] Cd Length: 333 Bit Score: 69.17 E-value: 4.18e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 16 IALAAPLAG-ESILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMVKN-GISAVIGHACSGASV 93
Cdd:cd06331 2 IGLLTPLSGpASVYGRAIANGAELAVEEINAAGGVLGRPVELVVEDDASDPATAVAAARRLIQQdKVDAIVGPITSATRN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 94 PASLVYQEDGVLMLSPSSSVPKLTERgldLVFRLFGRDDRLADAMANHVARKYAdKQIAVIHDKRSYGKGLADGFKdgln 173
Cdd:cd06331 82 AVAPVAERAKVPLLYPTFYEGGECSP---YLFCFGEVPNQQLDPLIPWLMEEYG-KKFYLIGSDYVWPRTMNDAAR---- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 174 krklreAVYDALSG----------DSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAASPAAF 243
Cdd:cd06331 154 ------RVIEAHGGevvgeeylplGTTDFSSVIEKIKASGADVVLSTLVGADAVTFLKQFAAAGLRRKVRIAALLFDENT 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 244 WQAAGP-AAEGVvfasIAADPTFEGLD-AIGKALIEA--------GRPVTIYGLSAYAAVTVFAQAVRHAKSAEPKAVAA 313
Cdd:cd06331 228 LAGLGAeAAEGI----YSVLSYFQSLDtPENKAFVAAyrkkfgedAPPITSLSEAAYEAVHLYAAAVEKAGSTDPEAVIA 303
|
330
....*....|....*...
gi 1032077502 314 ALHANEFATPLGNVRFSH 331
Cdd:cd06331 304 ALPGVSFDGPQGPVTMDP 321
|
|
| PBP1_RPA0668_benzoate-like |
cd20014 |
type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the ... |
55-330 |
6.93e-12 |
|
type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the active transport of lignin-derived benzoate derivative compounds, and its close homologs; This group includes RPA0668 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0668 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380667 [Multi-domain] Cd Length: 346 Bit Score: 65.72 E-value: 6.93e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 55 RLELV--DDHCDARQGALVATQMVKN-GISAVIGHACSGASVPASLVYQEDGVLMLSPSSSVPKLT-ERGLDLVFRLFGR 130
Cdd:cd20014 38 PIELVkeDDEADPDVALQKARKLIEQdKVDVLVGPVSSGVALAIRDVVEQAKVPLIVANAGANALTrAACSPYIFRTSFS 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 131 DDRLADAMANHVARKYaDKQIAVIHDKRSYGKGLADGFKDGLNKR--KLREAVYDALsGDSTAVLPLVRRLKDRGVDVV- 207
Cdd:cd20014 118 NWQLGYALGKYAAENV-GKTVVTIASDYAAGREVVAGFKEGFEAAggKVVGEIWTPL-GTTTDFSPYLTQIAASGPDAVy 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 208 -FFGGyfDDMVQLVRVSAEQDYH-------PTFFTGEAaspaaFWQAAGPAAEGVVFASIAADptfeGLD-AIGKALIEA 278
Cdd:cd20014 196 aFFAG--ADAVRFVKQYAEFGLKgkiplygPGFLTDED-----VLPALGEAAEGIITVLHYAP----TLDnPANRAFVAA 264
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1032077502 279 -----GRPVTIYGLSAYAAVTVFAQAVRHAKS--AEPKAVAAALHANEFATPLGNVRFS 330
Cdd:cd20014 265 yqakyGRLPDVYAVQGYDAAQVIDAALEAVGGdtSDKDILAAALELGSIDSPRGPFRFD 323
|
|
| PBP1_SBP-like |
cd06329 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
16-327 |
9.49e-12 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380552 [Multi-domain] Cd Length: 343 Bit Score: 65.37 E-value: 9.49e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 16 IALAAPLAGE-SILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMVKNGISAVIGhaCSGASVP 94
Cdd:cd06329 2 IAFIDPLSGPfASVGEIYLKGLQFAIEEINAGGGLLGRKIELVPFDNKGSPQEALIQLKKAIDQGIRFVLQ--GNSSAVA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 95 ASLVYQEDGVLMLSPSSSVPKLTERGLDLV----------FRLFGRDDRLADAMANHVARKYADKQIAVIHDKRSYGKGL 164
Cdd:cd06329 80 GALIDAIEKHNQRNPDKRVLFLNYGAEAPEltgakcsfwhFRFDANADMKMAALADYMKKDGSIKKVYLINQDYSFGRDV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 165 ADGFKDGLNKRKlreavYDA-LSGDSTAVL-------PLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGE 236
Cdd:cd06329 160 AAAAKKNLKKKR-----PDIeIVGEDLHPLgkvkdfsPYIAKIKASGADTVITGNWGNDLTLLMKAARDSGLKAPFYTYY 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 237 AASPAAFwQAAGPAAEGVVFASiaadptFEGLDAIGKALIEA---------GRPVTIYGLSAYAAVTVFAQAVRHAKSAE 307
Cdd:cd06329 235 ADGPGAP-AAIGEAGVGRLVAV------AYWHPNPKTPELEKfaeafrakyGRYPDFNIGRTYMGVEMLAAAIKKAGSTD 307
|
330 340
....*....|....*....|
gi 1032077502 308 PKAVAAALHANEFATPLGNV 327
Cdd:cd06329 308 PEKVAKALEGLSFDTPGGPV 327
|
|
| PBP1_aromatic_compounds-like |
cd06332 |
type 1 periplasmic binding proteins of active transport systems predicted to be involved in ... |
16-335 |
6.66e-11 |
|
type 1 periplasmic binding proteins of active transport systems predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; This group includes the type 1 periplasmic binding proteins of active transport systems that are predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; their substrate specificities are not well characterized, however. Members also exhibit close similarity to active transport systems for short chain amides and/or urea found in bacteria and archaea.
Pssm-ID: 380555 [Multi-domain] Cd Length: 336 Bit Score: 62.62 E-value: 6.66e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 16 IALAAPLAGE-SILGQDLKAGAEAAVKAINLGGGLLgePLRLELVDDHCDARQGALVATQMVKN-GISAVIGHACSGASV 93
Cdd:cd06332 2 IGLLAPLTGPfAALGEDMVRGFELALEEVGGEVAGR--KVELVVEDDAGDPDTAVTKARKLVEQdKVDVLIGPLSGDEGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 94 PASLVYQEDGVLMLSPSSSVPKLTERGLD-LVFRLFGRDDRLADAMANHVARKYADKQIAVIHDKRSYGKGLADGFKDGl 172
Cdd:cd06332 80 AVAPYAKEPGVPFINPVAGADDLTQRAKApNFFRTSFTGSQWSAPLGDYAYKELGYKKVATIGSDYAFGYEQAAGFKRG- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 173 nkrklreavYDALSGDSTAVL----------PLVRRLKDrGVDVVFFGGYFDDMVQLVRVSAE---QDYHPTFFTGEAAS 239
Cdd:cd06332 159 ---------FEAAGGEVVQEIwvplgttdfsPYIAQIPS-ADDAVFAFLGGADAVRFLKQYREfglKDKIPLIGGGTTVD 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 240 PAAFwQAAGPAAEGVvfasIAADPTFEGLD-AIGKALIEA-----GRPVTIYGLSAYAAVTVFAQAVRHAK-SAEPK-AV 311
Cdd:cd06332 229 ESVL-PAMGDAALGI----ISASHYAEGLDnPENKKFVAAykkkfGKLPSLYAAGGYDGAQAILEALEAVGgDVSDKqAL 303
|
330 340
....*....|....*....|....
gi 1032077502 312 AAALHANEFATPLGNVRFSHSGDA 335
Cdd:cd06332 304 AAALRKVKFDSPRGPFSFDENRNP 327
|
|
| PBP1_SBP-like |
cd19989 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
14-302 |
1.26e-10 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380644 [Multi-domain] Cd Length: 299 Bit Score: 61.52 E-value: 1.26e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 14 VVIALAAPLAGesiLGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMV-KNGISAVIGHACSGAS 92
Cdd:cd19989 4 VLTPLSGPYAA---LGEEARRGAQLAVEEINAAGGILGRPVELVVEDTEGKPATAVQKARKLVeQDGVDFLTGAVSSAVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 93 VPASLVYQEDGVLMLSPSSSVPKLT-ERGLDLVFRLFGRDDRLADAMANHVARKYADKQIAVIHDkRSYGKGLADGFKDG 171
Cdd:cd19989 81 LAVAPKAAELKVPYLVTVAADDELTgENCNRYTFRVNTSDRMIARALAPWLAENGGKKWYIVYAD-YAWGQSSAEAFKEA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 172 LNKRKLREAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAE----QDYhPTFFTGEAASPAAFwQAA 247
Cdd:cd19989 160 IEELGGEVVGTLFAPLGTTDFSSYITQISDSGADGLLLALAGSDAVNFLKQAGQfglgKKY-KIVGGILSIEPLAL-PAL 237
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1032077502 248 GPAAEGVVFaSIAADPTFEGLDAigKALIEA-----GRPVTIYGLSAYAAVTVFA-QAVRH 302
Cdd:cd19989 238 GDAAEGVYG-GVRYPPTLDTPAN--RAFVEAyekeyGEAPDNFAGEAYEAMQALAhQAVQP 295
|
|
| PBP1_ABC_ligand_binding-like |
cd19979 |
amino acid amide ABC transporter substrate binding protein haat family; This subgroup includes ... |
19-316 |
1.77e-10 |
|
amino acid amide ABC transporter substrate binding protein haat family; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380634 [Multi-domain] Cd Length: 350 Bit Score: 61.47 E-value: 1.77e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 19 AAPLAGESIlgqdlKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMVKNG-ISAVIGhacsGASVPASL 97
Cdd:cd19979 11 GSAASGEAI-----KRGIQLAIDEINAAGGLLGRKLELVAKDHRGNPARGVDNLREFAADPdVLAVFG----GLHSPVLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 98 VYQED----GVLMLSPSSSVPKLTERGLDL--VFRLFGRDDRLADAMANHVARKYAdKQIAVIHDKRSYGKGLADGFKDG 171
Cdd:cd19979 82 AELDFihelKIPYLVPWAAATPITRNGYSPnyIFRLSVDDSLAGPFLVEYALKKGC-KRPALLLENTGWGRSNLKAMTKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 172 LNKRKLREAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAASPAAFWQAAGPAA 251
Cdd:cd19979 161 LAKKGLQPVGVEWFNWGDTDAKPQLRALKAAGADAILLVANAPEGAAIVKALAALPERLPIISHWGITGGDFPELPREAL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 252 EGV---VFASIAADPTFEGldAIGKALIEAGR---PVTIYGLS---------AYAAVTVFAQAVRHAKSAEPKAVAAALH 316
Cdd:cd19979 241 SKIdlrFIQTFSFFDANQS--PRGKQVLARYKrryPVEDPESDipapvgfahAYDLTHLLALAIEQAGSTDRAAVRAALE 318
|
|
| PBP1_ABC_ligand_binding-like |
cd06341 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
34-301 |
2.28e-09 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380564 [Multi-domain] Cd Length: 340 Bit Score: 58.09 E-value: 2.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 34 AGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGALVATQMVKN-GISAVIGhACSGASVPASLVYQEDGVLMLSPSSS 112
Cdd:cd06341 21 AGAEARFGLANAAGGINGRKVEYVWCDDQSDPATNLQAARQLVEDeKVFALVG-SSSAASGSANDYLAQAGIPVVGGAGV 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 113 VPklTERGLDLVFRLFGRDDRLADAMANHVARKYADKQIAVIHDKRSYGKGLADGFKDGLNKRKLREAVYDALSGDSTAV 192
Cdd:cd06341 100 SV--WCFRNMFSNFFSLGGGGSTTTYGQYAAALGGTKAAVVVTDIPAASQQLAQQLAASLRAAGVEVVGTAPYAAAAPDY 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 193 LPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAEQDYHPTFFTGEAASPAAFWQAAGPAAEGVVFASIAAdpTFEG----- 267
Cdd:cd06341 178 TAVAQAAKAAGADAVVGVLDPDVAARVLKAARAQGLDLKVALSPSGYDPSVLAAYGAALAGVSVASTFL--PFEAdtpav 255
|
250 260 270
....*....|....*....|....*....|....*..
gi 1032077502 268 ---LDAIGKALIEAGRPVTIYGLSAYAAVTVFAQAVR 301
Cdd:cd06341 256 kayRAAMAKYAPELQDPLQQFALSGYIAADLFVRGLE 292
|
|
| PBP1_AmiC |
cd06357 |
periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding ... |
188-330 |
1.85e-08 |
|
periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding fold protein family; This group includes the periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding fold protein family. AmiC controls expression of the amidase operon by the ligand-triggered conformational switch. In the absence of ligand or presence of butyramide (repressor), AmiC (the ligand sensor and negative regulator) adopts an open conformation and inhibits the transcription antitermination function of AmiR by direct protein-protein interaction. In the presence of inducing ligands such as acetamide, AmiC adopts a closed conformation which disrupts a silencing AmiC-AmiR complex and the expression of amidase and other genes of the operon are induced.
Pssm-ID: 380580 [Multi-domain] Cd Length: 357 Bit Score: 55.28 E-value: 1.85e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 188 DSTAVLPLVRRLKDRGVDVVF---FGgyfDDMVQLVRVSAEQDYHPT------FFTGEAASPAAfwqaAGPAAEGvvfaS 258
Cdd:cd06357 172 GDTDFAEIIEEIKSLKPDVVFstlVG---DSIYAFYRAYAEAGLDPAdmpiasLTTSEAEVAAI----GAEAAAG----H 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 259 IAADPTFEGLD-AIGKALIEA-------GRPVTIYGLSAYAAVTVFAQAVRHAKSAEPKAVAAALHANEFATPLGNVRFS 330
Cdd:cd06357 241 YTSAPYFQSIDtPENRAFVEAyrarfgdDAVTSAVAEAAYFQVHLLARAIERAGSDDPEAIRAALYGQEFDAPQGPVRID 320
|
|
| PBP1_SBP-like |
cd06328 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
60-329 |
2.84e-08 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in gram-negative and gram-positive bacteria. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380551 [Multi-domain] Cd Length: 336 Bit Score: 54.61 E-value: 2.84e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 60 DDHCDARQGALVATQMVKN-GISAVIGHACSGASVPASLVYQEDGVLMLSPSSSVPKLTERGLDL-VFRLfGRDDrLADA 137
Cdd:cd06328 48 DDQGDPDTAKAAATELIGDdGVDILVGTVSSAVALALAPVAEQNKKILIVGPAAADSITGENWNKyTFRT-SRNS-WQDA 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 138 MAN-HVARKYADKQIAVIHDKRSYGKGLADGFKDGLNKRKLREAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDM 216
Cdd:cd06328 126 IAGaKALADPLGKSVAFLAQDYAFGQDGVAAFKKALEAKGGKIVGEELVPVTTTDFTPYLQRILDAKPDVLFVAWAGTGA 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 217 VQLVRVSAEQDYHPTFFTGEAASPAAFWQAAGPAAEGVVFASIaadpTFEGL------DAIGKALIEA-GRPVTIYGLSA 289
Cdd:cd06328 206 LTLWQQLADQGVLDDIKVVTGGPDIATLAALGDALPGIEGLTY----YYYGLpknpvnDWLVKAHKERyNAPPDLFTAGG 281
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1032077502 290 YAAVTVFAQAVRHAKS-AEPKAVAAALHANEFATPLGNVRF 329
Cdd:cd06328 282 FAAAQAVVRALEKAGGdTDVEKLIAALEGLTFETPKGKMTI 322
|
|
| PBP1_SBP-like |
cd19987 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
15-329 |
2.28e-07 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380642 [Multi-domain] Cd Length: 353 Bit Score: 51.95 E-value: 2.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 15 VIALAAPLAGE-SILGQDLKAGAEAAVKAINLGGGLLGEPLRL----------ELV--DDHCDARQGALVATQMV-KNGI 80
Cdd:cd19987 1 TIGLNVPLSGPyAPQGEDQRRGFELAVDHLNNGGGLVDKDSRLsgdgilgkkvELVtaDTETKADTAVDNAKRLIeQDGA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 81 SAVIGHACSGASVPASLVYQEDGVLMLSPSSSVPKLT-ERGLDLVFRLFGRDDRLADAMANHVARKYA-DKQIAVIHDKR 158
Cdd:cd19987 81 VMITGGSSSAVAVAAQKLAQKEGVLYFAGLSHSNDTTgKDCHRYGFRECFNAHMSAKALAPYLVEKFGkDRKYFYLTADY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 159 SYGKGLADGFKDGLNKRKLREAVYDALSGDSTAVLPLVRRLKDRGVDVVFFGGYFDDMV----QLVRVSAEQDY-----H 229
Cdd:cd19987 161 TWGHSTEQSMREYTEAHGWKTVGNPATPLGETDFSAALLNAADSGADVLVLVLFGRDMVnalkQAKQFGLLKKMdivvpL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 230 PTFFTGEaaspaafwQAAGPAAEGvVFASIAADPTFEGLDAIGKALIEA-----GRPVTIYGLSAYAAVTVFAQAVRHAK 304
Cdd:cd19987 241 LTAFMAE--------SVGPEIMEG-VLGTVNWHWSLPDDYSYAFGKAEAfekeyGAYPSQAAASAYVQVLQYAAAVERAG 311
|
330 340
....*....|....*....|....*
gi 1032077502 305 SAEPKAVAAALHANEFATPLGNVRF 329
Cdd:cd19987 312 SFDPPAVIRALEGHEYTLLKGEQYW 336
|
|
| PBP1_glutamate_receptors-like |
cd06269 |
ligand-binding domain of family C G-protein couples receptors (GPCRs), membrane bound guanylyl ... |
54-254 |
7.05e-06 |
|
ligand-binding domain of family C G-protein couples receptors (GPCRs), membrane bound guanylyl cyclases such as natriuretic peptide receptors (NPRs), and N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of ionotropic glutamate rece; This CD represents the ligand-binding domain of the family C G-protein couples receptors (GPCRs), membrane bound guanylyl cyclases such as the family of natriuretic peptide receptors (NPRs), and the N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the ionotropic glutamate receptors, all of which are structurally similar and related to the periplasmic-binding fold type 1 family. The family C GPCRs consists of metabotropic glutamate receptor (mGluR), a calcium-sensing receptor (CaSR), gamma-aminobutyric acid receptor (GABAbR), the promiscuous L-alpha-amino acid receptor GPR6A, families of taste and pheromone receptors, and orphan receptors. Truncated splicing variants of the orphan receptors are not included in this CD. The family C GPCRs are activated by endogenous agonists such as amino acids, ions, and sugar based molecules. Their amino terminal ligand-binding region is homologous to the bacterial leucine-isoleucine-valine binding protein (LIVBP) and a leucine binding protein (LBP). The ionotropic glutamate receptors (iGluRs) have an integral ion channel and are subdivided into three major groups based on their pharmacology and structural similarities: NMDA receptors, AMPA receptors, and kainate receptors. The family of membrane bound guanylyl cyclases is further divided into three subfamilies: the ANP receptor (GC-A)/C-type natriuretic peptide receptor (GC-B), the heat-stable enterotoxin receptor (GC-C)/sensory organ specific membrane GCs such as retinal receptors (GC-E, GC-F), and olfactory receptors (GC-D and GC-G).
Pssm-ID: 380493 [Multi-domain] Cd Length: 332 Bit Score: 47.41 E-value: 7.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 54 LRLELVDDHCDARQGALVATQMVKN-GISAVIGHACSGASVPASLVYQEDGVLMLSPSSSVPKLTER-GLDLVFRLFGRD 131
Cdd:cd06269 41 LGLAIRDSECNPTQALLSACDLLAAaKVVAILGPGCSASAAPVANLARHWDIPVLSYGATAPGLSDKsRYAYFLRTVPPD 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 132 DRLADAMANHVaRKYADKQIAVIHDKRSYGKGLADGFKDGLNKRKLREAVYDAL-SGDSTAVLPLVRRLKDRGVDVVFFG 210
Cdd:cd06269 121 SKQADAMLALV-RRLGWNKVVLIYSDDEYGEFGLEGLEELFQEKGGLITSRQSFdENKDDDLTKLLRNLRDTEARVIILL 199
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1032077502 211 GYFDDMVQLVRVSAE-----QDYHPTFFTGEAASPAAFWQAAGPAAEGV 254
Cdd:cd06269 200 ASPDTARSLMLEAKRldmtsKDYVWFVIDGEASSSDEHGDEARQAAEGA 248
|
|
| PBP1_Nba-like |
cd06359 |
type 1 periplasmic binding component of active transport systems predicted to be involved in ... |
16-333 |
1.28e-05 |
|
type 1 periplasmic binding component of active transport systems predicted to be involved in 2-nitrobenzoic acid degradation pathway; This group includes the type 1 periplasmic binding component of active transport systems that are predicted to be involved in 2-nitrobenzoic acid degradation pathway; their substrate specificities are not well characterized.
Pssm-ID: 380582 [Multi-domain] Cd Length: 333 Bit Score: 46.48 E-value: 1.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 16 IALAAPLAGE-SILGQDLKAGAEAAVKAINLGGGLlgEPLRLELVDDHCDARQGALVATQMV-KNGISAVIGHACSG--- 90
Cdd:cd06359 2 IGFITTLSGPaAVLGQDMRDGFNLALEQLGGKLGG--LPVEVVVEDDQLKPDVAKQAAERLIeRDKVDFVTGIIFSNvml 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 91 ASVPASLvyqEDGVLMLSPSSSVPKLTERGLD-LVFRLFGRDDRLADAMAnHVARKYADKQIAVIHDKRSYGKGLADGFK 169
Cdd:cd06359 80 AVVKPVV---DSKVFYISANAGPSDLAGKGCNpNFFVTSWQNDQLHEAAG-KYANDKGYKRVYLLAPNYQAGKDALAGFK 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 170 DGLnKRKLREAVYDALSG-DSTAVLPLVRRLKdrgVDVVFFGgYFDDM-VQLVRVSAEQDYHPT--FFTGEAASPAAFWQ 245
Cdd:cd06359 156 RTY-KGEVVGEIYTPLGQlDFSAELAQIRAAK---PDAVFAF-YPGGMgVNFVKQYAQAGLKKKipLYTVGTLDDEDLLP 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 246 AAGPAAEGVVFASIAAdptfEGLD-AIGKALIEA-----GRPVTIYGLSAYAAVTVFAQAVRHAKS--AEPKAVAAALHA 317
Cdd:cd06359 231 AMGDAALGVLSVSQWS----PDLDnPENKRFVAAfrkkyGRPPSNYAAQGYDAALLIDAAVKAVGGdlSDKDALRAALRK 306
|
330
....*....|....*.
gi 1032077502 318 NEFATPLGNVRFSHSG 333
Cdd:cd06359 307 ADFKSVRGAFRFNNNQ 322
|
|
| PBP1_alkylbenzenes-like |
cd06360 |
type 1 periplasmic binding component of active transport systems predicted be involved in ... |
14-329 |
1.59e-05 |
|
type 1 periplasmic binding component of active transport systems predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; This group includes the type 1 periplasmic binding component of active transport systems that are predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; their substrate specificity is not well characterized, however.
Pssm-ID: 380583 [Multi-domain] Cd Length: 357 Bit Score: 46.13 E-value: 1.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 14 VVIALAAPLAgesILGQDLKAGAEAAVKAINLGGGLlgEPLRLELVDDHCDARQGALVATQMVKNGISAVIGHACSGASV 93
Cdd:cd06360 4 VLLPLTGPLA---VNGEDVRDGFELYFDEIGNQVAG--RKIELIVEDDEGKPDVGLTKARKLVERDKVHVLAGIVSSAVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 94 PA--SLVYQEDGVLMLSPSSSVPKLTERGLDLVFRLFGRDDRLADAMANHVARKYADKQIAVIHDKRSYGKGLADGFKDG 171
Cdd:cd06360 79 YAvrDYVVEQKIPLVISNAGAAPLTQELASPYIFRTSFSNGQYDAPFGQYAYEKLGYRRIAVMASDYAAGHEQAGAFART 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 172 LNKR--KLREAVYDALsgDSTAVLPLVRRLKDRGVDVVFFGGYFDDMVQLVRVSAE---QDYHPTFFTGEAASPAaFWQA 246
Cdd:cd06360 159 FKQAggKVVQEIYPPL--GTADFAPYLARIQQDAADAVWAFFAGADAIRFVKQYDEyglKGKLPLVGIGGLVDDA-ILPE 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 247 AGPAAEGVVFA---SIAADpTFEGldaigKALIEA-----GRPVTIYGLSAYAAVTVFAQAVRHAKS--AEPKAVAAALH 316
Cdd:cd06360 236 QGDAALGIVSYlhySAALD-TPEN-----KAFVQAyrkkyGRDPGLYAEGGYVAARAIAEALEAVKGnvEDKEAFLEALR 309
|
330
....*....|...
gi 1032077502 317 ANEFATPLGNVRF 329
Cdd:cd06360 310 KVRFEAPRGPFRF 322
|
|
| PBP1_GPCR_family_C-like |
cd06350 |
ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory ... |
77-176 |
1.80e-05 |
|
ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory transmission on the cellular surface through initial binding of glutamate; categorized into ionotropic glutamate receptors (iGluRs) and metabotropic glutamate receptors (m; Ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory transmission on the cellular surface through initial binding of glutamate and are categorized into ionotropic glutamate receptors (iGluRs) and metabotropic glutamate receptors (mGluRs). The metabotropic glutamate receptors (mGluR) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. The mGluRs are coupled to G proteins and are thus distinct from the iGluRs which internally contain ligand-gated ion channels. The mGluR structure is divided into three regions: the extracellular region, the seven-spanning transmembrane region and the cytoplasmic region. The extracellular region is further divided into the ligand-binding domain (LBD) and the cysteine-rich domain. The LBD has sequence similarity to the LIVBP, which is a bacterial periplasmic protein (PBP), as well as to the extracellular region of both iGluR and the gamma-aminobutyric acid (GABA)b receptor. iGluRs are divided into three main subtypes based on pharmacological profile: NMDA, AMPA, and kainate receptors. All family C GPCRs have a large extracellular N terminus that contain a domain with homology to bacterial periplasmic amino acid-binding proteins.
Pssm-ID: 380573 Cd Length: 350 Bit Score: 46.13 E-value: 1.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 77 KNGISAVIGHACSGASVPASLVYQEDGVLMLSPSSSVPKLTERGLdlvFRLFGR----DDRLADAMA---NHVARKYadk 149
Cdd:cd06350 92 PPNIVAVIGAASSSVSIAVANLLGLFKIPQISYASTSPELSDKIR---YPYFLRtvpsDTLQAKAIAdllKHFNWNY--- 165
|
90 100
....*....|....*....|....*..
gi 1032077502 150 qIAVIHDKRSYGKGLADGFKDGLNKRK 176
Cdd:cd06350 166 -VSTVYSDDDYGRSGIEAFEREAKERG 191
|
|
| PBP1_FmdD-like |
cd06355 |
periplasmic component (FmdD) of an active transport system for short-chain amides and urea ... |
273-329 |
1.97e-05 |
|
periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); This group includes the periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF), found in Methylophilus methylotrophus, and its homologs from other bacteria. FmdD, a type 1 periplasmic binding protein, is induced by short-chain amides and urea and repressed by excess ammonia, while FmdE and FmdF are hydrophobic transmembrane proteins. FmdDEF is predicted to be an ATP-dependent transporter and closely resembles the periplasmic binding protein and the two transmembrane proteins present in various hydrophobic amino acid-binding transport systems.
Pssm-ID: 380578 [Multi-domain] Cd Length: 347 Bit Score: 46.03 E-value: 1.97e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1032077502 273 KALIEAGRPVTIYGLSAYAAVTVFAQAVRHAKSAEPKAVAAALHANEFATPLGNVRF 329
Cdd:cd06355 263 KAKYGADRVTSDPMEAAYLGVYLWAQAVEKAGSFDPDAVRAALKGQSFEAPGGTVTV 319
|
|
| PBP1_YraM_LppC_lipoprotein-like |
cd06339 |
periplasmic binding component of lipoprotein LppC, an immunodominant antigen; This subgroup ... |
16-220 |
3.37e-04 |
|
periplasmic binding component of lipoprotein LppC, an immunodominant antigen; This subgroup includes periplasmic binding component of lipoprotein LppC, an immunodominant antigen, whose molecular function is not characterized. Members of this subgroup are predicted to be involved in transport of lipid compounds, and they are sequence similar to the family of ABC-type hydrophobic amino acid transporters (HAAT).
Pssm-ID: 380562 [Multi-domain] Cd Length: 331 Bit Score: 42.26 E-value: 3.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 16 IALAAPLAGE-SILGQDLKAGAEAAVKAINLgggllgEPLRLELVDDHcDARQGALVATQMVKNGISAVIGHACSGASVP 94
Cdd:cd06339 2 IALLLPLSGPyAAAGQAIRDGIELALFDAGG------SRPELRVYDTG-GPEGAAAAYQQAVAEGADLIIGPLLKSSVAA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 95 ASLVYQEDGVLMLSPSSSVPKLTERGldlVFRLFGRDDRLADAMANHVARKYAdKQIAVIHDKRSYGKGLADGFKDGLNK 174
Cdd:cd06339 75 LAAAAQALGVPVLALNNDESATAGPG---LFQFGLSPEDEARQAARYAVQQGL-RRFAVLAPDNAYGQRVANAFREAWQA 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1032077502 175 RKLREAVYDALSGDSTAVLPLVRRLKD----------------------RGVDVVFFGGYFDDMVQLV 220
Cdd:cd06339 151 LGGTVVAVESYDPDETDFSAAIRRLLGvdqsearirqlgellefeprrrQDFDAIFLPAGPEQARLIA 218
|
|
| PBP1_ABC_ligand_binding-like |
cd06334 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
15-306 |
6.97e-04 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380557 [Multi-domain] Cd Length: 360 Bit Score: 41.07 E-value: 6.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 15 VIALAAPLAGE-SILGQDLKAGAEAAVKAINLGGGLLGEPLRLELVDDHCDARQGalVAT---QMVKNGISAVIGHAcSG 90
Cdd:cd06334 1 KIGLLTDLTGPtADVGKPYAQGVRDYLNYVNEEGGINGVKIELEECDTGYKVPRA--VACykrLKAQDGVVAILGWG-TG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 91 ASVPASLVYQEDGVLMLSPSSSvPKLTERG--LDLVFrLFGRDDR-----LADAMANHVARKYADKQIAVIHDKRSYGKG 163
Cdd:cd06334 78 DTEALAPRVAKDKIPYISASYG-RSLADDGkvFPYNF-FVGATYSsqaraLLKYIAQEWGGKLKGPKVAFVYHDSPFGRE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 164 -------LAD--GFKDGLnkrklrEAVYDALSGDSTAVlplVRRLKDRGVDVVFFGGYFDDMVQLVR----VSAEQDYHP 230
Cdd:cd06334 156 pipalkaYAKelGFEVVA------EQVPSPGALDATAQ---WLRIRRAGPDYVIIQGTGGSVAVIIKdakrLGLKTKFIG 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032077502 231 TFFTGEaaSPAAfwQAAGPAAEGVVFASIAADPT-FEGLDAIGKALIEAGRP------VTIYGLSAYAAVTVFAQAVRHA 303
Cdd:cd06334 227 NIWGGD--EDLI--KLAGDAAEGYVGVSPFAFGTdDPPGKEIVEEVAKKGKGdgpeevGTVYYNRGWATAMLAVEAIRRA 302
|
...
gi 1032077502 304 KSA 306
Cdd:cd06334 303 DKA 305
|
|
| PBP1_NPR_GC-like |
cd06352 |
ligand-binding domain of membrane guanylyl-cyclase receptors; Ligand-binding domain of ... |
59-175 |
9.22e-03 |
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ligand-binding domain of membrane guanylyl-cyclase receptors; Ligand-binding domain of membrane guanylyl-cyclase receptors. Membrane guanylyl cyclases (GC) have a single membrane-spanning region and are activated by endogenous and exogenous peptides. This family can be divided into three major subfamilies: the natriuretic peptide receptors (NPRs), sensory organ-specific membrane GCs, and the enterotoxin/guanylin receptors. The binding of peptide ligands to the receptor results in the activation of the cytosolic catalytic domain. Three types of NPRs have been cloned from mammalian tissues: NPR-A/GC-A, NPR-B/ GC-B, and NPR-C. In addition, two of the GCs, GC-D and GC-G, appear to be pseudogenes in humans. Atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) are produced in the heart, and both bind to the NPR-A. NPR-C, also termed the clearance receptor, binds each of the natriuretic peptides and can alter circulating levels of these peptides. The ligand binding domain of the NPRs exhibits strong structural similarity to the type 1 periplasmic binding fold protein family.
Pssm-ID: 380575 [Multi-domain] Cd Length: 391 Bit Score: 37.72 E-value: 9.22e-03
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gi 1032077502 59 VDDHCDARQGALVATQMV-KNGISAVIGHACSGASVPASLV---YQedgVLMLSPSSSVPKLTERG-LDLVFRLFGRDDR 133
Cdd:cd06352 48 RDSCCDESEAVGAAADLIyKRNVDVFIGPACSAAADAVGRLatyWN---IPIITWGAVSASFLDKSrYPTLTRTSPNSLS 124
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90 100 110 120
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gi 1032077502 134 LADAMANhVARKYADKQIAVIHDKR-SYGKGLADGFKDGLNKR 175
Cdd:cd06352 125 LAEALLA-LLKQFNWKRAAIIYSDDdSKCFSIANDLEDALNQE 166
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