|
Name |
Accession |
Description |
Interval |
E-value |
| GAS2 |
smart00243 |
Growth-Arrest-Specific Protein 2 Domain; GROWTH-ARREST-SPECIFIC PROTEIN 2 Domain |
3247-3319 |
6.70e-42 |
|
Growth-Arrest-Specific Protein 2 Domain; GROWTH-ARREST-SPECIFIC PROTEIN 2 Domain
Pssm-ID: 128539 Cd Length: 73 Bit Score: 148.75 E-value: 6.70e-42
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 3247 DKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRARG 3319
Cdd:smart00243 1 DKIDDEVKRIVEDCKCPTKFQVEKISEGKYRFGDSQILRLVRILRSTVMVRVGGGWETLDEYLLKHDPCRAKG 73
|
|
| GAS2 |
pfam02187 |
Growth-Arrest-Specific Protein 2 Domain; The GAR2 domain is common in plakin family members ... |
3249-3317 |
1.31e-37 |
|
Growth-Arrest-Specific Protein 2 Domain; The GAR2 domain is common in plakin family members and Gas2 family members. The GAR domain comprises around 57 amino acids and has been shown to bind to microtubules.
Pssm-ID: 460480 Cd Length: 69 Bit Score: 136.57 E-value: 1.31e-37
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 3249 IEDEVTRQVAQCKCAKRFQVEQIGENKYRFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRA 3317
Cdd:pfam02187 1 LDDEVRRIVAQCTCPTKFPVEKVGEGKYRFGDSQKLVFVRILRSHVMVRVGGGWDTLEEYLLKHDPCRA 69
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
834-1309 |
6.97e-37 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 155.10 E-value: 6.97e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 834 PSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASiVSL----EEEDVTAAAVSAPERATV 909
Cdd:PHA03247 2607 DPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGR-VSRprraRRLGRAAQASSPPQRPRR 2685
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 910 PAVTVSVPEGTAAVAAVSSPEETAPA----VAAAITQEGMSAVAGFSPEWAALAITVPiteedgTPEGPVTPATTVHAPE 985
Cdd:PHA03247 2686 RAARPTVGSLTSLADPPPPPPTPEPAphalVSATPLPPGPAAARQASPALPAAPAPPA------VPAGPATPGGPARPAR 2759
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 986 EPDTAAVRVSTPeePASPAAAVP--TPEEPTSPAA----AVPTPEEPTSPAAAVPPPEePTSPAAAVPTPEEPTsPAAAV 1059
Cdd:PHA03247 2760 PPTTAGPPAPAP--PAAPAAGPPrrLTRPAVASLSesreSLPSPWDPADPPAAVLAPA-AALPPAASPAGPLPP-PTSAQ 2835
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1060 PTPEEPTSPAAAVPTPEE----PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP-ASPAAAVPTPEEPASPA 1134
Cdd:PHA03247 2836 PTAPPPPPGPPPPSLPLGgsvaPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESfALPPDQPERPPQPQAPP 2915
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1135 AAVPTPEEPA--FPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPT-SPAASVPTPAAMVAT 1211
Cdd:PHA03247 2916 PPQPQPQPPPppQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVpQPAPSREAPASSTPP 2995
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1212 LEEFTSPAASvptseepaSLAAAVSNPEEPTSPAAA------VPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAA 1285
Cdd:PHA03247 2996 LTGHSLSRVS--------SWASSLALHEETDPPPVSlkqtlwPPDDTEDSDADSLFDSDSERSDLEALDPLPPEPHDPFA 3067
|
490 500
....*....|....*....|....
gi 2245149928 1286 AVSNLEEPASPAAAVPTPEVAAIP 1309
Cdd:PHA03247 3068 HEPDPATPEAGARESPSSQFGPPP 3091
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2352-2568 |
1.17e-36 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 139.12 E-value: 1.17e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2352 LGQFQHALEELMSWLTHTEELLDAQRPISgDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAgDDASSLRS 2431
Cdd:cd00176 2 LQQFLRDADELEAWLSEKEELLSSTDYGD-DLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGH-PDAEEIQE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2432 RLEAMNQCWESVLQKTEEREQQLQSTLQQAQgFHSEIEDFLLELTRMESQLSASKPtGGLPETAREQLDTHMELYSQLKA 2511
Cdd:cd00176 80 RLEELNQRWEELRELAEERRQRLEEALDLQQ-FFRDADDLEQWLEEKEAALASEDL-GKDLESVEELLKKHKELEEELEA 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 2512 KEETYNQLLDKGRlMLLSRDDSGSGSKTEQSVALLEQKWHVVSSKMEERKSKLEEAL 2568
Cdd:cd00176 158 HEPRLKSLNELAE-ELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
961-1367 |
2.69e-36 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 153.17 E-value: 2.69e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 961 TVPITEEDGTPEGPV--TPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTP-----EEPTSPAAAV 1033
Cdd:PHA03247 2567 SVPPPRPAPRPSEPAvtSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPspaanEPDPHPPPTV 2646
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1034 PPPEEPTS------------------PAAAVPTPEEPTSPAAavPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1095
Cdd:PHA03247 2647 PPPERPRDdpapgrvsrprrarrlgrAAQASSPPQRPRRRAA--RPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPG 2724
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1096 AAVPTPEEPTSPAAAVP--TPEEPASPA--AAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEES--ASAAVAVPTPEES 1169
Cdd:PHA03247 2725 PAAARQASPALPAAPAPpaVPAGPATPGgpARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVAslSESRESLPSPWDP 2804
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1170 ASPAAAVPTPAESASFAAVVATLEEPtsPAASVPT-PAAMVATLEEFTSPAASV---------PTSEEPASLAAAVSNPE 1239
Cdd:PHA03247 2805 ADPPAAVLAPAAALPPAASPAGPLPP--PTSAQPTaPPPPPGPPPPSLPLGGSVapggdvrrrPPSRSPAAKPAAPARPP 2882
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1240 EPTSPAAAVPtlEEPTSSAAAVLTPEELSSPAA-----SVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVP 1314
Cdd:PHA03247 2883 VRRLARPAVS--RSTESFALPPDQPERPPQPQAppppqPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVP 2960
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1315 TPEVPAIPAAAvppmeevspIGVPFLGVSAHTDSVPISEEGTPVLEEASSTGM 1367
Cdd:PHA03247 2961 QPWLGALVPGR---------VAVPRFRVPQPAPSREAPASSTPPLTGHSLSRV 3004
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2792-3004 |
2.24e-35 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 135.65 E-value: 2.24e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2792 QFMDALQALVDWLYKVEPQLAEDQPVHgDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENSRDDTTWVKGQLQ 2871
Cdd:cd00176 4 QFLRDADELEAWLSEKEELLSSTDYGD-DLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEEIQERLE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2872 ELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHmLLEWLSEAEQTLRfRGALPDDTEALQSLIDTHKEFMKKVEEKRV 2951
Cdd:cd00176 83 ELNQRWEELRELAEERRQRLEEALDLQQFFRDADD-LEQWLEEKEAALA-SEDLGKDLESVEELLKKHKELEEELEAHEP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 2952 DVNSAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETAL 3004
Cdd:cd00176 161 RLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2573-2787 |
1.45e-34 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 133.34 E-value: 1.45e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2573 EFQNSLQEFINWLTLAEQSLNIASPPSLiLNTVLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQkQDVVLIKNLL 2652
Cdd:cd00176 4 QFLRDADELEAWLSEKEELLSSTDYGDD-LESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGH-PDAEEIQERL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2653 VSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWkKLIDWLEDAESHLDSElEISNDPDKIKLQLSKHKEFQKTLGGKQ 2732
Cdd:cd00176 82 EELNQRWEELRELAEERRQRLEEALDLQQFFRDAD-DLEQWLEEKEAALASE-DLGKDLESVEELLKKHKELEEELEAHE 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2245149928 2733 PVYDTTIRTGRALKEKtLLPEDSQKLDNFLGEVRDKWDTVCGKSVERQHKLEEAL 2787
Cdd:cd00176 160 PRLKSLNELAEELLEE-GHPDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
829-1374 |
1.77e-34 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 147.01 E-value: 1.77e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 829 PVLQRPSRtAAVPTvkdaldAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDI-------LVASIVSLEE---EDVTA 898
Cdd:PHA03247 2478 PVYRRPAE-ARFPF------AAGAAPDPGGGGPPDPDAPPAPSRLAPAILPDEPVgepvhprMLTWIRGLEElasDDAGD 2550
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 899 AAVSAPERATVPAVTVSVPEGTAAV----AAVSS--------PEETAPAVAAAITQE--GMSAVAGFSPEWAALAITVPI 964
Cdd:PHA03247 2551 PPPPLPPAAPPAAPDRSVPPPRPAPrpsePAVTSrarrpdapPQSARPRAPVDDRGDprGPAPPSPLPPDTHAPDPPPPS 2630
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 965 TEEDGTPEGPVTPATTVHAPEEPDTAAV-RVSTP---EEPASPAAAVPTPEEPTSPAA----------AVPTPEEPT--- 1027
Cdd:PHA03247 2631 PSPAANEPDPHPPPTVPPPERPRDDPAPgRVSRPrraRRLGRAAQASSPPQRPRRRAArptvgsltslADPPPPPPTpep 2710
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1028 SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA--AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE-EP 1104
Cdd:PHA03247 2711 APHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGgpARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAvAS 2790
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1105 TSPAA-AVPTPEEPASPAAAVPTPEePASPAAAVPTPEEPAfPAPAVPTPEESASAAVAVPTPEE-SASPAAAVPTPAES 1182
Cdd:PHA03247 2791 LSESReSLPSPWDPADPPAAVLAPA-AALPPAASPAGPLPP-PTSAQPTAPPPPPGPPPPSLPLGgSVAPGGDVRRRPPS 2868
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1183 ASFAAVVATLEEPtsPAASVPTPaamvatleeftspaasvPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVL 1262
Cdd:PHA03247 2869 RSPAAKPAAPARP--PVRRLARP-----------------AVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQP 2929
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1263 TPEElsspaasvPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSP---IGVPF 1339
Cdd:PHA03247 2930 QPPP--------PPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTpplTGHSL 3001
|
570 580 590
....*....|....*....|....*....|....*
gi 2245149928 1340 LGVSAHTDSVPISEEGTPVLEEASSTgMWIKEDLD 1374
Cdd:PHA03247 3002 SRVSSWASSLALHEETDPPPVSLKQT-LWPPDDTE 3035
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2679-2895 |
1.46e-32 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 127.56 E-value: 1.46e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2679 RAKQFHEAWKKLIDWLEDAESHLDSElEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKtlLPEDSQKL 2758
Cdd:cd00176 1 KLQQFLRDADELEAWLSEKEELLSST-DYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEE--GHPDAEEI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2759 DNFLGEVRDKWDTVCGKSVERQHKLEEALLFSgQFMDALQALVDWLYKVEPQLAEDQPVHgDLDLVMNLMDAHKVFQKEL 2838
Cdd:cd00176 78 QERLEELNQRWEELRELAEERRQRLEEALDLQ-QFFRDADDLEQWLEEKEAALASEDLGK-DLESVEELLKKHKELEEEL 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 2839 GKRTGTVQVLKRSGRELIENSR-DDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQAL 2895
Cdd:cd00176 156 EAHEPRLKSLNELAEELLEEGHpDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2132-2349 |
2.63e-30 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 121.01 E-value: 2.63e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2132 LAEKFWYDMAALLTTIKDTQDIVHDLESPGiDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGEtEKPEVR 2211
Cdd:cd00176 1 KLQQFLRDADELEAWLSEKEELLSSTDYGD-DLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHP-DAEEIQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2212 KSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMfDWLDNTVIKLCTMPPvGTDLNTVKDQLNEMKEFKVEVY 2291
Cdd:cd00176 79 ERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDADDLE-QWLEEKEAALASEDL-GKDLESVEELLKKHKELEEELE 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 2292 QQQIEMEKLNHQGELMLKKATDEtDRDIIREPLTELKHLWENLGEKIAHRQHKLEGAL 2349
Cdd:cd00176 157 AHEPRLKSLNELAEELLEEGHPD-ADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
963-1316 |
3.70e-28 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 125.67 E-value: 3.70e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 963 PITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAavPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSP 1042
Cdd:PHA03307 24 PPATPGDAADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFE--PPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1043 AAAVPTPEEPTSPaaavPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAA 1122
Cdd:PHA03307 102 REGSPTPPGPSSP----DPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLS 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1123 AVPTPEE-PASPAAAVP--TPEEPAFPAPAVPTPEESASAAVAVPTPEESaspaAAVPTPAESASFAAVVA-------TL 1192
Cdd:PHA03307 178 SPEETARaPSSPPAEPPpsTPPAAASPRPPRRSSPISASASSPAPAPGRS----AADDAGASSSDSSSSESsgcgwgpEN 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1193 EEPTSPAASVPTP----AAMVATLEEFTSPAASVPTSEEPASLAAAVSNP--EEPTSPAAAVPTLE-EPTSSAAAVLTPE 1265
Cdd:PHA03307 254 ECPLPRPAPITLPtriwEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPgsGPAPSSPRASSSSSsSRESSSSSTSSSS 333
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 2245149928 1266 ELSSPAASVPTPEEPASPAAAvsnleePASPAAAVPTPEVAAIPAASVPTP 1316
Cdd:PHA03307 334 ESSRGAAVSPGPSPSRSPSPS------RPPPPADPSSPRKRPRPSRAPSSP 378
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
956-1317 |
5.50e-28 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 124.33 E-value: 5.50e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 956 AALAITVPITEEDGTPEGPVTPATTVHAPeepDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPP 1035
Cdd:PRK07764 372 RGLLARLERLERRLGVAGGAGAPAAAAPS---AAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNA 448
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1036 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA-AVPTPEEPTSPAAAV---------------- 1098
Cdd:PRK07764 449 PAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAApAAPAAPAGADDAATLrerwpeilaavpkrsr 528
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1099 ------------------------PTP-------------------------------EEPTSPAAAVPTPEEPASPAAA 1123
Cdd:PRK07764 529 ktwaillpeatvlgvrgdtlvlgfSTGglarrfaspgnaevlvtalaeelggdwqveaVVGPAPGAAGGEGPPAPASSGP 608
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1124 VPTPEEPASPAAAVPTPeePAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVP 1203
Cdd:PRK07764 609 PEEAARPAAPAAPAAPA--APAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPA 686
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1204 tpaamvatleeftsPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTleEPTSSAAAVLTPEElsSPAASVPTPEEPASP 1283
Cdd:PRK07764 687 --------------PAAPAAPAGAAPAQPAPAPAATPPAGQADDPAA--QPPQAAQGASAPSP--AADDPVPLPPEPDDP 748
|
410 420 430
....*....|....*....|....*....|....
gi 2245149928 1284 AAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPE 1317
Cdd:PRK07764 749 PDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEE 782
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
810-1190 |
5.50e-28 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 124.33 E-value: 5.50e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 810 PEKQVTKAGNTEPvleewiPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIV 889
Cdd:PRK07764 381 LERRLGVAGGAGA------PAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAP 454
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 890 SLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAitqeGMSAVAGFSPEWAALAITVP------ 963
Cdd:PRK07764 455 SPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPA----GADDAATLRERWPEILAAVPkrsrkt 530
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 964 -------------------------------------------ITEEDG---TPEGPVTPATTVHAPEEPDTAAVRVSTP 997
Cdd:PRK07764 531 waillpeatvlgvrgdtlvlgfstgglarrfaspgnaevlvtaLAEELGgdwQVEAVVGPAPGAAGGEGPPAPASSGPPE 610
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 998 EEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAvPTPEE 1077
Cdd:PRK07764 611 EAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPA-PAPAA 689
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1078 PTSPAAAVPTPEEPTSPAAAVPTP-EEPTSPAAAVPTPEEPASPAAA--VPTPEEPASPAAAVPTPEEPAFPAPAVPTPE 1154
Cdd:PRK07764 690 PAAPAGAAPAQPAPAPAATPPAGQaDDPAAQPPQAAQGASAPSPAADdpVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAA 769
|
410 420 430
....*....|....*....|....*....|....*.
gi 2245149928 1155 ESASAAVAVPTPEESASPAAAVPTPAESASFAAVVA 1190
Cdd:PRK07764 770 PAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEEVA 805
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
947-1317 |
1.24e-27 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 123.17 E-value: 1.24e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 947 AVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAA--AVPTPEEPTSPAAAVPTPE 1024
Cdd:PRK07764 370 DERGLLARLERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAApqPAPAPAPAPAPPSPAGNAP 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1025 EPTSPAAAvPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE-------------- 1090
Cdd:PRK07764 450 AGGAPSPP-PAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRErwpeilaavpkrsr 528
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1091 ------------------------PTSPAA-AVPTPEEP----------------------TSPAAAVPTPEEPASPAAA 1123
Cdd:PRK07764 529 ktwaillpeatvlgvrgdtlvlgfSTGGLArRFASPGNAevlvtalaeelggdwqveavvgPAPGAAGGEGPPAPASSGP 608
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1124 VPTPEEPASPAAAVPTPeePAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASvP 1203
Cdd:PRK07764 609 PEEAARPAAPAAPAAPA--APAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPA-P 685
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1204 TPAAMVATLEEFTSPAASVPTSEEPASLAAAvsnpEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASP 1283
Cdd:PRK07764 686 APAAPAAPAGAAPAQPAPAPAATPPAGQADD----PAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPP 761
|
410 420 430
....*....|....*....|....*....|....
gi 2245149928 1284 AAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPE 1317
Cdd:PRK07764 762 PAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDD 795
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
897-1311 |
6.13e-27 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 120.86 E-value: 6.13e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 897 TAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITqegmsAVAGFSPEWAALAITVPiteedgtpeGPVT 976
Cdd:PRK07764 374 LLARLERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPA-----AAAAPAPAAAPQPAPAP---------APAP 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 977 PATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEE----- 1051
Cdd:PRK07764 440 APPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRErwpei 519
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1052 ---------------------------------PTSPAA-AVPTPEEPTSPAAAV---------PTPEEPTSPAAAVPTP 1088
Cdd:PRK07764 520 laavpkrsrktwaillpeatvlgvrgdtlvlgfSTGGLArRFASPGNAEVLVTALaeelggdwqVEAVVGPAPGAAGGEG 599
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1089 EEPTSPAAAVPTPEEPTSPAAAVPTPeePASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEE 1168
Cdd:PRK07764 600 PPAPASSGPPEEAARPAAPAAPAAPA--APAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAA 677
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1169 SASPAAAvPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATleefTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAV 1248
Cdd:PRK07764 678 PAAPPPA-PAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAA----QPPQAAQGASAPSPAADDPVPLPPEPDDPPDPA 752
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1249 PTLEEPTssaaavltpeelssPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAA 1311
Cdd:PRK07764 753 GAPAQPP--------------PPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDA 801
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2244-2458 |
8.08e-27 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 111.00 E-value: 8.08e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2244 QYQDTLQAMFDWLDNTvIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRdiIREP 2323
Cdd:cd00176 4 QFLRDADELEAWLSEK-EELLSSTDYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEE--IQER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2324 LTELKHLWENLGEKIAHRQHKLEGALLALgQFQHALEELMSWLTHTEELLDAQrPISGDPKVIEVELAKHHVLKNDVLAH 2403
Cdd:cd00176 81 LEELNQRWEELRELAEERRQRLEEALDLQ-QFFRDADDLEQWLEEKEAALASE-DLGKDLESVEELLKKHKELEEELEAH 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2245149928 2404 QATVETVNKAGNELLESSAGDDASSLRSRLEAMNQCWESVLQKTEEREQQLQSTL 2458
Cdd:cd00176 159 EPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1000-1369 |
8.16e-27 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 121.58 E-value: 8.16e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1000 PASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAV-PTPEEPTSPA--AAVPTPEEPTSPAAAVPTPe 1076
Cdd:PHA03247 2475 PGAPVYRRPAEARFPFAAGAAPDPGGGGPPDPDAPPAPSRLAPAILPdEPVGEPVHPRmlTWIRGLEELASDDAGDPPP- 2553
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1077 ePTSPAAAVPTPEEPTSPAAAVPTPEEP--TSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPE 1154
Cdd:PHA03247 2554 -PLPPAAPPAAPDRSVPPPRPAPRPSEPavTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPS 2632
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1155 ESASA-----AVAVPTPEE----SASPAAAVPTPAESASFAAVV-ATLEEPTSPAASVPtpaamVATLEEFTSPAASVPT 1224
Cdd:PHA03247 2633 PAANEpdphpPPTVPPPERprddPAPGRVSRPRRARRLGRAAQAsSPPQRPRRRAARPT-----VGSLTSLADPPPPPPT 2707
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1225 SEEPASlaAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPA--ASVPTPEEPASPAAAVSNLEEPASPAAAVPT 1302
Cdd:PHA03247 2708 PEPAPH--ALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGgpARPARPPTTAGPPAPAPPAAPAAGPPRRLTR 2785
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2245149928 1303 PEVA--AIPAASVPTP-EVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTP-VLEEASSTGMWI 1369
Cdd:PHA03247 2786 PAVAslSESRESLPSPwDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPgPPPPSLPLGGSV 2856
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
831-1175 |
1.28e-25 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 117.73 E-value: 1.28e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 831 LQRPSRTAAVPTVKDALDAALPSPEEGT-------SIAAVPAPEGTAVVAALVPFPHEDIL------VASIVSLEEEDVT 897
Cdd:PHA03247 2680 PQRPRRRAARPTVGSLTSLADPPPPPPTpepaphaLVSATPLPPGPAAARQASPALPAAPAppavpaGPATPGGPARPAR 2759
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 898 AAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEE--------------TAPAVAAAITQEGMSAVAGFSPEWAALAITVP 963
Cdd:PHA03247 2760 PPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSEsreslpspwdpadpPAAVLAPAAALPPAASPAGPLPPPTSAQPTAP 2839
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 964 IT-----EEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVP-TPEEPTSPAAAVPPPE 1037
Cdd:PHA03247 2840 PPppgppPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPdQPERPPQPQAPPPPQP 2919
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1038 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP-------------------TSPAAAVPTPEEPTSPAAAV 1098
Cdd:PHA03247 2920 QPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPqpwlgalvpgrvavprfrvPQPAPSREAPASSTPPLTGH 2999
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1099 PTP------------EEPTSPAAA------VPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAA 1160
Cdd:PHA03247 3000 SLSrvsswasslalhEETDPPPVSlkqtlwPPDDTEDSDADSLFDSDSERSDLEALDPLPPEPHDPFAHEPDPATPEAGA 3079
|
410
....*....|....*
gi 2245149928 1161 VAVPTPEESASPAAA 1175
Cdd:PHA03247 3080 RESPSSQFGPPPLSA 3094
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
1475-1688 |
3.29e-25 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 106.38 E-value: 3.29e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1475 KFQDALEPLLSWLADTEELIANQKPPSAEyKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAElADREKITGQL 1554
Cdd:cd00176 4 QFLRDADELEAWLSEKEELLSSTDYGDDL-ESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGH-PDAEEIQERL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1555 ESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEpISDFLSVTEKKLANSEPVGTQTaKIQQQIIRHKALNEEIVNRK 1634
Cdd:cd00176 82 EELNQRWEELRELAEERRQRLEEALDLQQFFRDADD-LEQWLEEKEAALASEDLGKDLE-SVEELLKKHKELEEELEAHE 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 1635 KNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKTRYADITVTSSKALRTLEQAR 1688
Cdd:cd00176 160 PRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2897-3141 |
1.35e-24 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 104.45 E-value: 1.35e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2897 QAEVFRDTVHMLLEWLSEAEQTLRfRGALPDDTEALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDcITTIK 2976
Cdd:cd00176 1 KLQQFLRDADELEAWLSEKEELLS-STDYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPD-AEEIQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2977 HWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELlawiQWAETTLIQRDQEPIPQNIDRVKALIAEHQTFMEE 3056
Cdd:cd00176 79 ERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDADDLE----QWLEEKEAALASEDLGKDLESVEELLKKHKELEEE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 3057 MTRKQPDVDRVTKtykrkniepTHAPFIEKSRSGGRkslsqptpppmpilsqsEAKNPRINQLSARWQQVWLLALERQRK 3136
Cdd:cd00176 155 LEAHEPRLKSLNE---------LAEELLEEGHPDAD-----------------EEIEEKLEELNERWEELLELAEERQKK 208
|
....*
gi 2245149928 3137 LNDAL 3141
Cdd:cd00176 209 LEEAL 213
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
1911-2130 |
1.89e-24 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 104.06 E-value: 1.89e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1911 QFWETYEELSPWIEETRALIAQLPSPAiDHEQLRQQQEEMRQLRESIAEHKPHIDKLLKIGPQLKELNPEEGEMVEEKYQ 1990
Cdd:cd00176 4 QFLRDADELEAWLSEKEELLSSTDYGD-DLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEEIQERLE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1991 KAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSrlrmpPLIPAEVDKIRECISDNKSATVELEK 2070
Cdd:cd00176 83 ELNQRWEELRELAEERRQRLEEALDLQQFFRDADDLEQWLEEKEAALAS-----EDLGKDLESVEELLKKHKELEEELEA 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2071 LQPSFEALKRRGEELIGRSQgadkDLAAKEIQDKLDQMVFFWEDIKARAEEREIKFLDVL 2130
Cdd:cd00176 158 HEPRLKSLNELAEELLEEGH----PDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
956-1316 |
7.23e-24 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 108.89 E-value: 7.23e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 956 AALAITVPITEEDGTPEGPV--TPATTVHAPEEPDTA--AVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTpeeptspAA 1031
Cdd:pfam17823 62 AATAAPAPVTLTKGTSAAHLnsTEVTAEHTPHGTDLSepATREGAADGAASRALAAAASSSPSSAAQSLPA-------AI 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1032 AVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPeepTSPAAAVPTPEEPTSPAAAvptpeePTSPAAAVPTPEEPTSPAAAV 1111
Cdd:pfam17823 135 AALPSEAFSAPRAAACRANASAAPRAAIAAA---SAPHAASPAPRTAASSTTA------ASSTTAASSAPTTAASSAPAT 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1112 PTPEEPASPAAAVPTPEEPASPAAAVPTpeepAFPAPAVPTpeesasAAVAVPTPeesaspaAAVPTPAESASFAAVVAT 1191
Cdd:pfam17823 206 LTPARGISTAATATGHPAAGTALAAVGN----SSPAAGTVT------AAVGTVTP-------AALATLAAAAGTVASAAG 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1192 LEEPTSPAASVPtpaamvatleeftSPAASVPTSeepaslaAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPA 1271
Cdd:pfam17823 269 TINMGDPHARRL-------------SPAKHMPSD-------TMARNPAAPMGAQAQGPIIQVSTDQPVHNTAGEPTPSPS 328
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1272 ASVPTPEEPASPAAAVSNL--------EEP-ASPAAAVPT---PEVAAIPAASVPTP 1316
Cdd:pfam17823 329 NTTLEPNTPKSVASTNLAVvtttkaqaKEPsASPVPVLHTsmiPEVEATSPTTQPSP 385
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
1001-1263 |
9.03e-24 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 109.97 E-value: 9.03e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1001 ASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPT--SPAAAVPTPEEPTSPAAAVPTPEeP 1078
Cdd:PRK12323 372 AGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPArrSPAPEALAAARQASARGPGGAPA-P 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1079 TSPAAAVPTPEEPtspaAAVPTPEEPTSPAAAVPTPEEPASPAAAVPT---PEEPASPAAAVPTPEEPAfPAPAVPTPEE 1155
Cdd:PRK12323 451 APAPAAAPAAAAR----PAAAGPRPVAAAAAAAPARAAPAAAPAPADDdppPWEELPPEFASPAPAQPD-AAPAGWVAES 525
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1156 SASAAVAVPTPEESASPAAAVPTPAESAsfAAVVATLEEPTSPAASVPTPAAMVAtlEEFTSPAASVPTSEEPASLA--- 1232
Cdd:PRK12323 526 IPDPATADPDDAFETLAPAPAAAPAPRA--AAATEPVVAPRPPRASASGLPDMFD--GDWPALAARLPVRGLAQQLArqs 601
|
250 260 270
....*....|....*....|....*....|....*
gi 2245149928 1233 --AAVSNpeEPTSPAAAVPTLEEPTSSA--AAVLT 1263
Cdd:PRK12323 602 elAGVEG--DTVRLRVPVPALAEAEVVErlQAALT 634
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
999-1303 |
1.43e-23 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 109.94 E-value: 1.43e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 999 EPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEE-PTSPAAAVPTPEE 1077
Cdd:PRK07003 359 EPAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEaPPAAPAPPATADR 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1078 PTSPAAA-VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPtpeeS 1156
Cdd:PRK07003 439 GDDAADGdAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAP----A 514
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1157 ASAAVAVPTPEESASPAAAVPTPAESasfaavvatleeptSPAASVPTPAAMVATLEEftspaASVPTSEEPASLAAAvs 1236
Cdd:PRK07003 515 AASREDAPAAAAPPAPEARPPTPAAA--------------APAARAGGAAAALDVLRN-----AGMRVSSDRGARAAA-- 573
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1237 npeePTSPAAAVPTLEEPTSSAAAVltpeelsspaaSVPTPEEPASPAAAVSNLEEPASPAAAVPTP 1303
Cdd:PRK07003 574 ----AAKPAAAPAAAPKPAAPRVAV-----------QVPTPRARAATGDAPPNGAARAEQAAESRGA 625
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
898-1316 |
5.89e-23 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 108.33 E-value: 5.89e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 898 AAAVSAPERATVPAVTVSVPE----GTAAVAAVSSPEETAPAVAAAITQEGMSAVAGfSPEWAALAITVPITEEDGTPEG 973
Cdd:PHA03307 13 AAAEGGEFFPRPPATPGDAADdllsGSQGQLVSDSAELAAVTVVAGAAACDRFEPPT-GPPPGPGTEAPANESRSTPTWS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 974 PVTPATTVHAPEEPDTAAVRVSTPEEPA--SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEE 1051
Cdd:PHA03307 92 LSTLAPASPAREGSPTPPGPSSPDPPPPtpPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQ 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1052 PTSPAAAVPTPEEPTSPAAAVPTPEepTSPAAAVPTPEEPTSPAAAvPTPEEPTSPA--AAVPTPEEPASPAAAV----- 1124
Cdd:PHA03307 172 AALPLSSPEETARAPSSPPAEPPPS--TPPAAASPRPPRRSSPISA-SASSPAPAPGrsAADDAGASSSDSSSSEssgcg 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1125 --PTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASV 1202
Cdd:PHA03307 249 wgPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSS 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1203 PTPAamvatleEFTSPAASVPTSEEPASLAAavsnPEEPTSPAAAVPTLEEPTSSAAAvltpeelSSPAASVPTPEEP-A 1281
Cdd:PHA03307 329 TSSS-------SESSRGAAVSPGPSPSRSPS----PSRPPPPADPSSPRKRPRPSRAP-------SSPAASAGRPTRRrA 390
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 2245149928 1282 SPAAAVSNLEE------PASPAAAVPTPEVAAIPAASVPTP 1316
Cdd:PHA03307 391 RAAVAGRARRRdatgrfPAGRPRPSPLDAGAASGAFYARYP 431
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2460-2677 |
7.04e-23 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 99.44 E-value: 7.04e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2460 QAQGFHSEIEDFLLELTRMESQLSASKPtGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKG-RLMLLSRDDSgsgSK 2538
Cdd:cd00176 1 KLQQFLRDADELEAWLSEKEELLSSTDY-GDDLESVEALLKKHEALEAELAAHEERVEALNELGeQLIEEGHPDA---EE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2539 TEQSVALLEQKWHVVSSKMEERKSKLEEALNLATEFQnSLQEFINWLTLAEQSLNiASPPSLILNTVLSQIEEHKVFANE 2618
Cdd:cd00176 77 IQERLEELNQRWEELRELAEERRQRLEEALDLQQFFR-DADDLEQWLEEKEAALA-SEDLGKDLESVEELLKKHKELEEE 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 2619 VNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDAR 2677
Cdd:cd00176 155 LEAHEPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
950-1306 |
1.28e-22 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 106.86 E-value: 1.28e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 950 GFSP-EWAALAITV-------PITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVP 1021
Cdd:PRK07003 339 GLAPdEYAGFTMTLlrmlafePAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAA 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1022 TPEEPTSPAAAVPPP---EEPTSPAAA-VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1097
Cdd:PRK07003 419 AATRAEAPPAAPAPPataDRGDDAADGdAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAA 498
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1098 VPTPEEPTSPAAAVPTpeepASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAvptpeESASAAVAV-------------P 1164
Cdd:PRK07003 499 PSAATPAAVPDARAPA----AASREDAPAAAAPPAPEARPPTPAAAAPAARA-----GGAAAALDVlrnagmrvssdrgA 569
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1165 TPEESASPAAAVPTPAESAsfaavvatleePTSPAASVPTPAAMVATLEEFTSPAASVPtseePASLAAAVSNPEEPTSP 1244
Cdd:PRK07003 570 RAAAAAKPAAAPAAAPKPA-----------APRVAVQVPTPRARAATGDAPPNGAARAE----QAAESRGAPPPWEDIPP 634
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1245 AAAVP-TLEE----PTSSAAAV---------LTPEELSSPAASVPT-PEEPASPAAAVSNLEEPASPAAAVPTPEVA 1306
Cdd:PRK07003 635 DDYVPlSADEgfggPDDGFVPVfdsgpddvrVAPKPADAPAPPVDTrPLPPAIPLDAIGFDGEWPALAARLPLKGVA 711
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
983-1366 |
1.47e-22 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 106.61 E-value: 1.47e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 983 APEEPDT---AAVRVSTPEE--PASPAAAVPTPEEPTSPAAA-VPTPEEPTSPAAAVPPPEEPTSPAAAvPTPEEPTSPA 1056
Cdd:PRK07764 364 LPSASDDergLLARLERLERrlGVAGGAGAPAAAAPSAAAAApAAAPAPAAAAPAAAAAPAPAAAPQPA-PAPAPAPAPP 442
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1057 AAVPTPEEPTSPAAAvPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEE--PA--- 1131
Cdd:PRK07764 443 SPAGNAPAGGAPSPP-PAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRErwPEila 521
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1132 -------------SPAAAVPTPEEP----AFPAP------------------------------AVPTPEESASAAVAVP 1164
Cdd:PRK07764 522 avpkrsrktwailLPEATVLGVRGDtlvlGFSTGglarrfaspgnaevlvtalaeelggdwqveAVVGPAPGAAGGEGPP 601
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1165 TPEESASPAAAV-PTPAESAsfaavvatlEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTS 1243
Cdd:PRK07764 602 APASSGPPEEAArPAAPAAP---------AAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAK 672
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1244 PAAAVPTLEEPTSSAAAVLTPeelSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPA 1323
Cdd:PRK07764 673 AGGAAPAAPPPAPAPAAPAAP---AGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPP 749
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 2245149928 1324 AAVPPMEEVSPIGVPF--LGVSAHTDSVPISEEGTPVLEEASSTG 1366
Cdd:PRK07764 750 DPAGAPAQPPPPPAPApaAAPAAAPPPSPPSEEEEMAEDDAPSMD 794
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
1051-1316 |
2.95e-22 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 105.70 E-value: 2.95e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1051 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEP 1130
Cdd:PRK07003 359 EPAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADR 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1131 ASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESasfaavvatleEPTSPAASVPTPAAMVA 1210
Cdd:PRK07003 439 GDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAF-----------EPAPRAAAPSAATPAAV 507
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1211 TLEEftsPAASVPTSEEPASLAAAVSNPEEPTsPAAAVPTLEEPTSSAAA-VLTPEELSSPAASVPTPEEPASPAAAVSN 1289
Cdd:PRK07003 508 PDAR---APAAASREDAPAAAAPPAPEARPPT-PAAAAPAARAGGAAAALdVLRNAGMRVSSDRGARAAAAAKPAAAPAA 583
|
250 260
....*....|....*....|....*..
gi 2245149928 1290 LEEPASPAAAVPTPEVAAIPAASVPTP 1316
Cdd:PRK07003 584 APKPAAPRVAVQVPTPRARAATGDAPP 610
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
968-1302 |
6.01e-22 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 104.61 E-value: 6.01e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 968 DGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPeepTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVP 1047
Cdd:pfam05109 426 ESTTTSPTLNTTGFAAPNTTTGLPSSTHVPTNLTAPASTGPTV---STADVTSPTPAGTTSGASPVTPSPSPRDNGTESK 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1048 TPEEpTSPAAAVPTPE-EPTSPAAAVPTPeeptSPAAAVPTPEEpTSPAAAVPTPE-EPTSPAAAVPTPeepaSPAAAVP 1125
Cdd:pfam05109 503 APDM-TSPTSAVTTPTpNATSPTPAVTTP----TPNATSPTLGK-TSPTSAVTTPTpNATSPTPAVTTP----TPNATIP 572
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1126 TPEEpASPAAAVPTPEepafPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVP-T 1204
Cdd:pfam05109 573 TLGK-TSPTSAVTTPT----PNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSlR 647
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1205 PAAMVATLEEFTSPAAsvpTSEEPASLAAAVSNPEEPT--SPAAAVPTLEEPTSSAAAVLTPEELSSPAASvPTPEEP-- 1280
Cdd:pfam05109 648 PSSISETLSPSTSDNS---TSHMPLLTSAHPTGGENITqvTPASTSTHHVSTSSPAPRPGTTSQASGPGNS-STSTKPge 723
|
330 340
....*....|....*....|....*..
gi 2245149928 1281 -----ASPAAAVSNLEEPASPAAAVPT 1302
Cdd:pfam05109 724 vnvtkGTPPKNATSPQAPSGQKTAVPT 750
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
973-1203 |
1.15e-21 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 103.42 E-value: 1.15e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 973 GPVTPATTVHAPEEPDTAAVRVSTPEePASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEeP 1052
Cdd:PRK12323 373 GPATAAAAPVAQPAPAAAAPAAAAPA-PAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPA-P 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1053 TSPAAAVPTPEEPtspaAAVPTPEEPTSPAAAVPTPEEPtsPAAAVPTPEEPTspaaavPTPEEPASPAAAVPTPEEPAS 1132
Cdd:PRK12323 451 APAPAAAPAAAAR----PAAAGPRPVAAAAAAAPARAAP--AAAPAPADDDPP------PWEELPPEFASPAPAQPDAAP 518
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1133 PAAAVPTPEEPAF--PAPAVPTPEESASAAvAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSpAASVP 1203
Cdd:PRK12323 519 AGWVAESIPDPATadPDDAFETLAPAPAAA-PAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPAL-AARLP 589
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
888-1282 |
3.40e-21 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 102.30 E-value: 3.40e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 888 IVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAitqegmsavagfspewaalAITVPitee 967
Cdd:pfam05109 420 IFSKAPESTTTSPTLNTTGFAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTA-------------------DVTSP---- 476
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 968 dgTPEGPVTPATTVHAPEEPDTAAVRVSTPEEpASPAAAVPTPeeptSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVP 1047
Cdd:pfam05109 477 --TPAGTTSGASPVTPSPSPRDNGTESKAPDM-TSPTSAVTTP----TPNATSPTPAVTTPTPNATSPTLGKTSPTSAVT 549
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1048 TPE-EPTSPAAAVPTPeeptSPAAAVPTPEEpTSPAAAVPTPeeptSPAAAVPTPEEpTSPAAAvpTPEEPASPAAAVPT 1126
Cdd:pfam05109 550 TPTpNATSPTPAVTTP----TPNATIPTLGK-TSPTSAVTTP----TPNATSPTVGE-TSPQAN--TTNHTLGGTSSTPV 617
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1127 PEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAA---SVP 1203
Cdd:pfam05109 618 VTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPTGGENITQVTPASTSThhvSTS 697
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1204 TPAAMVATLEEFTSPAASvPTSEEPASLAAA-------VSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPT 1276
Cdd:pfam05109 698 SPAPRPGTTSQASGPGNS-STSTKPGEVNVTkgtppknATSPQAPSGQKTAVPTVTSTGGKANSTTGGKHTTGHGARTST 776
|
....*.
gi 2245149928 1277 peEPAS 1282
Cdd:pfam05109 777 --EPTT 780
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
984-1224 |
8.69e-21 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 100.00 E-value: 8.69e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 984 PEEPDTAAVRVSTPEEPASPAA-AVPTPEEPTSPAAAVPtpeEPTSPAAAVPPPEEPTSPAAAVPTPEEPTS-PAAAVPT 1061
Cdd:PLN03209 330 PKESDAADGPKPVPTKPVTPEApSPPIEEEPPQPKAVVP---RPLSPYTAYEDLKPPTSPIPTPPSSSPASSkSVDAVAK 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1062 PEEPTSPAAAVPTPEEPTSPAAAVPTPEE-PTSPAAAVPTPEEPTSPAaavPTPEEPASPAAAVpTPEEPASPAAAVPTP 1140
Cdd:PLN03209 407 PAEPDVVPSPGSASNVPEVEPAQVEAKKTrPLSPYARYEDLKPPTSPS---PTAPTGVSPSVSS-TSSVPAVPDTAPATA 482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1141 -EEPAFPAPAVPTPeESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVP----------TPAAMV 1209
Cdd:PLN03209 483 aTDAAAPPPANMRP-LSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQhhaqpkprplSPYTMY 561
|
250
....*....|....*
gi 2245149928 1210 ATLEEFTSPAASVPT 1224
Cdd:PLN03209 562 EDLKPPTSPTPSPVL 576
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
994-1316 |
1.73e-20 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 100.23 E-value: 1.73e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 994 VSTPEEPASPAAavPTPEEPTSPAAAVPTPEEPTSPAAAVP----PPEEPTSPAAA--------------VPTPEEPTSP 1055
Cdd:pfam03154 174 LQAQSGAASPPS--PPPPGTTQAATAGPTPSAPSVPPQGSPatsqPPNQTQSTAAPhtliqqtptlhpqrLPSPHPPLQP 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1056 AAAVPTPeePTSPAAAVPTP----EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPA 1131
Cdd:pfam03154 252 MTQPPPP--SQVSPQPLPQPslhgQMPPMPHSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPP 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1132 S-PAAAVPTP--EEPAFPAP-AVPTPEESASAAVA-VPTPEESASPA-AAVPTPAESASFAAVVATLEEPTS-----PAA 1200
Cdd:pfam03154 330 SqSQLQSQQPprEQPLPPAPlSMPHIKPPPTTPIPqLPNPQSHKHPPhLSGPSPFQMNSNLPPPPALKPLSSlsthhPPS 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1201 SVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSN-------------------PEEPTSPAAAVPTLEEPTSSAAAV 1261
Cdd:pfam03154 410 AHPPPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAAShpptsglhqvpsqspfpqhPFVPGGPPPITPPSGPPTSTSSAM 489
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2245149928 1262 --LTPEELSSPAASVPTPEEPASPAAAV----SNLEEPASPAAAVPTPEVAAIPAASVPTP 1316
Cdd:pfam03154 490 pgIQPPSSASVSSSGPVPAAVSCPLPPVqikeEALDEAEEPESPPPPPRSPSPEPTVVNTP 550
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
1404-1579 |
2.53e-20 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 92.12 E-value: 2.53e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1404 EMFQKEqVDPLQMKLQQVNGLGQGLIQSAGKDCDVqgLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEpL 1483
Cdd:cd00176 43 EALEAE-LAAHEERVEALNELGEQLIEEGHPDAEE--IQERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDADD-L 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1484 LSWLADTEELIANQKPPSAEYKVvKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQLESLESRWTE 1563
Cdd:cd00176 119 EQWLEEKEAALASEDLGKDLESV-EELLKKHKELEEELEAHEPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEE 197
|
170
....*....|....*.
gi 2245149928 1564 LLSKAAARQKQLEDIL 1579
Cdd:cd00176 198 LLELAEERQKKLEEAL 213
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
910-1181 |
8.89e-20 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 97.61 E-value: 8.89e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 910 PAVTV-SVPEGTAAVA---AVSSPEETAPAVAAAITQEGMSAVAGfspewaalAITVPITEEDGTPEGPVTPATTVHAPE 985
Cdd:PRK07003 360 PAVTGgGAPGGGVPARvagAVPAPGARAAAAVGASAVPAVTAVTG--------AAGAALAPKAAAAAAATRAEAPPAAPA 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 986 EPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1065
Cdd:PRK07003 432 PPATADRGDDAADGDAPVPAKANARASADSRCDE-RDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDA 510
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1066 TSPAAAvPTPEEPTSPAAAVP--TPEEPTSPAAAV------------------------PTPEEPTSPAAAVPTPEEPAS 1119
Cdd:PRK07003 511 RAPAAA-SREDAPAAAAPPAPeaRPPTPAAAAPAAraggaaaaldvlrnagmrvssdrgARAAAAAKPAAAPAAAPKPAA 589
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1120 PAAAVPTPeepaSPAAAVPTPEEPAFPAPAVPTPEESASAavavPTPEESASPAAAVPTPAE 1181
Cdd:PRK07003 590 PRVAVQVP----TPRARAATGDAPPNGAARAEQAAESRGA----PPPWEDIPPDDYVPLSAD 643
|
|
| Streccoc_I_II |
NF033804 |
antigen I/II family LPXTG-anchored adhesin; Members of the antigen I/II family are adhesins ... |
911-1152 |
2.13e-19 |
|
antigen I/II family LPXTG-anchored adhesin; Members of the antigen I/II family are adhesins with a glucan-binding domain, two types of repetitive regions, an isopeptide bond-forming domain associated with shear resistance, and a C-terminal LPXTG motif for anchoring to the cell wall. They occur in oral Streptococci, and tend to be major cell surface adhesins. Members of this family include SspA and SspB from Streptococcus gordonii, antigen I/II from S. mutans, etc.
Pssm-ID: 468188 [Multi-domain] Cd Length: 1552 Bit Score: 96.93 E-value: 2.13e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 911 AVTVSVPEGTAAVAAVSS----PEETAPAVAAAITQEGMSAVAGFSPEWAALAITVP-ITEEDGTPegPVTPAttvhAPE 985
Cdd:NF033804 769 AISMSGPNNSVTVGAISAtnvmPSDEMPAVPGRDNTEGKKPNIWYSLNGKIRAVNVPkITKEKPTP--PVAPT----APQ 842
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 986 EPDTAAvrvstpEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1065
Cdd:NF033804 843 APTYEV------EKPLEPAPVAPTYENEPTPPVKTPDQPEPSKPEEPTYETEKPLEPAPVAPTYENEPTPPVKTPDQPEP 916
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1066 TSPAAAVPTPEEPTSPAAAV------PTPEEPTSPAAAVPTPEEPTSpaAAVPTPeepasPAAavPTPEEpaspaaaVPT 1139
Cdd:NF033804 917 SKPEEPTYETEKPLEPAPVApsyenePTPPVKTPDQPEPSKPVEPTY--DPLPTP-----PVA--PTPKQ-------LPT 980
|
250
....*....|...
gi 2245149928 1140 PeepafpaPAVPT 1152
Cdd:NF033804 981 P-------PAVPT 986
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
1079-1307 |
4.19e-19 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 94.94 E-value: 4.19e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1079 TSPAAAVPTPEEPTSPAAAVPTPEEPTsPAAAVPTPeePASPAAAVPTPEEPASPAAAVPTPEepAFPAPAVPTPEESAS 1158
Cdd:PRK12323 372 AGPATAAAAPVAQPAPAAAAPAAAAPA-PAAPPAAP--AAAPAAAAAARAVAAAPARRSPAPE--ALAAARQASARGPGG 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1159 AAVAVPTPeeSASPAAAVPTPAesASFAAVVATLEEPTSPAASVPTPAAmvatleeftSPAASVPTSEEPASLAAAVSNP 1238
Cdd:PRK12323 447 APAPAPAP--AAAPAAAARPAA--AGPRPVAAAAAAAPARAAPAAAPAP---------ADDDPPPWEELPPEFASPAPAQ 513
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1239 EEPTSPAAAVPTLEEPTSS----AAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAA 1307
Cdd:PRK12323 514 PDAAPAGWVAESIPDPATAdpddAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPALAA 586
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
2354-2455 |
5.35e-19 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 84.69 E-value: 5.35e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2354 QFQHALEELMSWLTHTEELLdAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSaGDDASSLRSRL 2433
Cdd:smart00150 2 QFLRDADELEAWLEEKEQLL-ASEDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEG-HPDAEEIEERL 79
|
90 100
....*....|....*....|..
gi 2245149928 2434 EAMNQCWESVLQKTEEREQQLQ 2455
Cdd:smart00150 80 EELNERWEELKELAEERRQKLE 101
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
1008-1256 |
6.19e-19 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 93.84 E-value: 6.19e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1008 PTPEEPTSPAAAVPTPEEPTSPAAAVPP-PEEPTSPAAAVPtpeEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS-PAAAV 1085
Cdd:PLN03209 328 VPPKESDAADGPKPVPTKPVTPEAPSPPiEEEPPQPKAVVP---RPLSPYTAYEDLKPPTSPIPTPPSSSPASSkSVDAV 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1086 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE-PASPAAAVPTPEEPASPAaavPTPEEPAFPaPAVPTPEESASAAVAVP 1164
Cdd:PLN03209 405 AKPAEPDVVPSPGSASNVPEVEPAQVEAKKTrPLSPYARYEDLKPPTSPS---PTAPTGVSP-SVSSTSSVPAVPDTAPA 480
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1165 TpeeSASPAAAVPTPAESA-SFAAVVATLEEPTSpaasvPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEE--- 1240
Cdd:PLN03209 481 T---AATDAAAPPPANMRPlSPYAVYDDLKPPTS-----PSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQHHAQpkp 552
|
250
....*....|....*..
gi 2245149928 1241 -PTSPAAAVPTLEEPTS 1256
Cdd:PLN03209 553 rPLSPYTMYEDLKPPTS 569
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
953-1204 |
1.11e-18 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 93.07 E-value: 1.11e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 953 PEWAALAITVPITEEDGTPEGPVTPATtvHAPEEPDTAAVRvstpeePASPAAAVPTPEEPTSPaaavpTPEEPTSPAAA 1032
Cdd:PLN03209 331 KESDAADGPKPVPTKPVTPEAPSPPIE--EEPPQPKAVVPR------PLSPYTAYEDLKPPTSP-----IPTPPSSSPAS 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1033 VPP------PEEPTSPAAAVPTPEEPTSPAAAVPTPEE-PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT 1105
Cdd:PLN03209 398 SKSvdavakPAEPDVVPSPGSASNVPEVEPAQVEAKKTrPLSPYARYEDLKPPTSPSPTAPTGVSPSVSSTSSVPAVPDT 477
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1106 SPAAAVPTPEEPASPAAAvptpeePASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAV-------PT 1178
Cdd:PLN03209 478 APATAATDAAAPPPANMR------PLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALAdeqhhaqPK 551
|
250 260
....*....|....*....|....*.
gi 2245149928 1179 PAESASFaAVVATLEEPTSPAASVPT 1204
Cdd:PLN03209 552 PRPLSPY-TMYEDLKPPTSPTPSPVL 576
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
989-1317 |
1.31e-18 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 93.83 E-value: 1.31e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 989 TAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTpeePTSPAAAVPTPEEPTSP 1068
Cdd:pfam05109 408 TATNATTTTHKVIFSKAPESTTTSPTLNTTGFAAPNTTTGLPSSTHVPTNLTAPASTGPT---VSTADVTSPTPAGTTSG 484
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1069 AAAV---PTPEEP---------TSPAAAVPTPE-EPTSPAAAVPTPeeptSPAAAVPTPEEpASPAAAVPTPEEPA-SPA 1134
Cdd:pfam05109 485 ASPVtpsPSPRDNgteskapdmTSPTSAVTTPTpNATSPTPAVTTP----TPNATSPTLGK-TSPTSAVTTPTPNAtSPT 559
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1135 AAVPTPEepafPAPAVPT-PEESASAAVAVPTPeESASPAAAVPTPAESASFAAVVATLEEP--TSPAASVptpAAMVAT 1211
Cdd:pfam05109 560 PAVTTPT----PNATIPTlGKTSPTSAVTTPTP-NATSPTVGETSPQANTTNHTLGGTSSTPvvTSPPKNA---TSAVTT 631
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1212 LEEFTSPAASVPTSEEPASLAAAVSnPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLE 1291
Cdd:pfam05109 632 GQHNITSSSTSSMSLRPSSISETLS-PSTSDNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTSQAS 710
|
330 340
....*....|....*....|....*....
gi 2245149928 1292 EPASPAAAVPTPEV---AAIPAASVPTPE 1317
Cdd:pfam05109 711 GPGNSSTSTKPGEVnvtKGTPPKNATSPQ 739
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
931-1147 |
3.89e-18 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 91.86 E-value: 3.89e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 931 ETAPAVAAAITqegmsaVAGFSPewaALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTP 1010
Cdd:PRK12323 371 GAGPATAAAAP------VAQPAP---AAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASA 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1011 EEPTSPAAAVPTPeePTSPAAAVPP----PEEPTSPAAAVPTPEEPTSPAAAVPT---PEEPTSPAAAVPTPEEPT---S 1080
Cdd:PRK12323 442 RGPGGAPAPAPAP--AAAPAAAARPaaagPRPVAAAAAAAPARAAPAAAPAPADDdppPWEELPPEFASPAPAQPDaapA 519
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1081 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPA 1147
Cdd:PRK12323 520 GWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPALAA 586
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
925-1298 |
4.93e-18 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 92.14 E-value: 4.93e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 925 AVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITV--PITEEDGTPEGPVTPATTVHapEEPDTAAVRVSTPEEPAS 1002
Cdd:pfam03154 173 VLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGspATSQPPNQTQSTAAPHTLIQ--QTPTLHPQRLPSPHPPLQ 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1003 PAAAVPTPeePTSPAAAVPTPEEPTsPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE----- 1077
Cdd:pfam03154 251 PMTQPPPP--SQVSPQPLPQPSLHG-QMPPMPHSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQqriht 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1078 -PTSPAAAVPTP--EEPTsPAAAVPTPE---EPTSPAAAVPTPE---EPASPAAAVP------TPEEPA-SPAAAVPTPE 1141
Cdd:pfam03154 328 pPSQSQLQSQQPprEQPL-PPAPLSMPHikpPPTTPIPQLPNPQshkHPPHLSGPSPfqmnsnLPPPPAlKPLSSLSTHH 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1142 EP-AFPAP------AVPTPEESASAAVAVPTPEESAsPAAAVPTPAESASFAAVVATLEEPTSPAASVP-TPAAMVAtle 1213
Cdd:pfam03154 407 PPsAHPPPlqlmpqSQQLPPPPAQPPVLTQSQSLPP-PAASHPPTSGLHQVPSQSPFPQHPFVPGGPPPiTPPSGPP--- 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1214 efTSPAASVPTSEEPASLAAAVSNPeEPTSPAAAVPTL---EEPTSSaaavltPEELSSPaasvPTPEEPASPAAAVSNL 1290
Cdd:pfam03154 483 --TSTSSAMPGIQPPSSASVSSSGP-VPAAVSCPLPPVqikEEALDE------AEEPESP----PPPPRSPSPEPTVVNT 549
|
....*...
gi 2245149928 1291 EEPASPAA 1298
Cdd:pfam03154 550 PSHASQSA 557
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
827-1249 |
7.72e-18 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 90.02 E-value: 7.72e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 827 WIPVLQRpSRTAAVPTVKDALDAALPSPEEG---TSIAAVPAPEGTA------VVAALVPFPHEDILVASIVSLEEEDVT 897
Cdd:pfam17823 9 WIFSLPL-SESHAAPADPRHFVLNKMWNGAGkqnASGDAVPRADNKSseq*nfCAATAAPAPVTLTKGTSAAHLNSTEVT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 898 AAAVSAPERATVPA--------VTVSVPeGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEW-AALAITVPITEED 968
Cdd:pfam17823 88 AEHTPHGTDLSEPAtregaadgAASRAL-AAAASSSPSSAAQSLPAAIAALPSEAFSAPRAAACRAnASAAPRAAIAAAS 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 969 GTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAA-AVPTPEEPTSpAAAVPppeePTSPAAAVP 1047
Cdd:pfam17823 167 APHAASPAPRTAASSTTAASSTTAASSAPTTAASSAPATLTPARGISTAAtATGHPAAGTA-LAAVG----NSSPAAGTV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1048 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPtpeeptSPAAAVPTPEEPTSPAAavPTPEEPASPAAAVPTp 1127
Cdd:pfam17823 242 TAAVGTVTPAALATLAAAAGTVASAAGTINMGDPHARRL------SPAKHMPSDTMARNPAA--PMGAQAQGPIIQVST- 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1128 EEPASPAAAVPTPE-EPAFPAPAVPTPEESASAAVAVPTPEESASPAAA-VPTPAESASFAAvvatleEPTSPAASvptP 1205
Cdd:pfam17823 313 DQPVHNTAGEPTPSpSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPSASpVPVLHTSMIPEV------EATSPTTQ---P 383
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 2245149928 1206 AAMVATleEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVP 1249
Cdd:pfam17823 384 SPLLPT--QGAAGPGILLAPEQVATEATAGTASAGPTPRSSGDP 425
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
963-1303 |
1.46e-17 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 90.52 E-value: 1.46e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 963 PITEED-----GTPEGPvtpattvHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAaavptpEEPTSPAAAVPPPE 1037
Cdd:PTZ00449 498 PIEEEDsdkhdEPPEGP-------EASGLPPKAPGDKEGEEGEHEDSKESDEPKEGGKPG------ETKEGEVGKKPGPA 564
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1038 EPTSPAAaVPT-------PEEPTSPAaavpTPEEPTSPAAAVpTPEEPTSPaaavPTPEEPTSP--AAAVPTPEEPTSPA 1108
Cdd:PTZ00449 565 KEHKPSK-IPTlskkpefPKDPKHPK----DPEEPKKPKRPR-SAQRPTRP----KSPKLPELLdiPKSPKRPESPKSPK 634
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1109 AAVPtPEEPASPAaavpTPEEPASPAaavpTPEEPAFPAPAV-PTPEESASAAVAvptpEESASPAAAVPTPAESASFAA 1187
Cdd:PTZ00449 635 RPPP-PQRPSSPE----RPEGPKIIK----SPKPPKSPKPPFdPKFKEKFYDDYL----DAAAKSKETKTTVVLDESFES 701
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1188 VVA-TLEEPTSPAASVPTPAAMV-ATLEEFTSPAASVPTSEEPaslaaavSNPEEPTSP-AAAVPTLEEPTSSAAAVLTP 1264
Cdd:PTZ00449 702 ILKeTLPETPGTPFTTPRPLPPKlPRDEEFPFEPIGDPDAEQP-------DDIEFFTPPeEERTFFHETPADTPLPDILA 774
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 2245149928 1265 EELSSP--AASVPTPEEPaspaaavsnLEEPASPAAAVPTP 1303
Cdd:PTZ00449 775 EEFKEEdiHAETGEPDEA---------MKRPDSPSEHEDKP 806
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
1801-2014 |
1.98e-17 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 83.65 E-value: 1.98e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1801 QQYEQAADAELAWVAETKRKLMALGPIRLEQdQTTAQLQVQKAFSIDIIRHKDSMDELfSHRSEIFGTCGEEQKTVLQEK 1880
Cdd:cd00176 3 QQFLRDADELEAWLSEKEELLSSTDYGDDLE-SVEALLKKHEALEAELAAHEERVEAL-NELGEQLIEEGHPDAEEIQER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1881 TESLIQQYEAISLLNSERYARLERAQVLVNQFWETYEELSpWIEETRALIAQLPSPAiDHEQLRQQQEEMRQLRESIAEH 1960
Cdd:cd00176 81 LEELNQRWEELRELAEERRQRLEEALDLQQFFRDADDLEQ-WLEEKEAALASEDLGK-DLESVEELLKKHKELEEELEAH 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2245149928 1961 KPHIDKLLKIGPQLKELNPEEGEM-VEEKYQKAENMYAQIKEEVRQRALALDEAV 2014
Cdd:cd00176 159 EPRLKSLNELAEELLEEGHPDADEeIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| Treacle |
pfam03546 |
Treacher Collins syndrome protein Treacle; |
810-1315 |
3.30e-17 |
|
Treacher Collins syndrome protein Treacle;
Pssm-ID: 460967 [Multi-domain] Cd Length: 531 Bit Score: 88.21 E-value: 3.30e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 810 PEKQVTKAGNTEPVLEEWIPVLQRPSR---TAAVPTVKDALDAALPSPEEGTSiAAVPAPEGTAVVAALVPFPHEDilva 886
Cdd:pfam03546 20 PEEDSESSSEEESDSEEETPAAKTPLQakpSGKTPQVRAASAPAKESPRKGAP-PVPPGKTGPAAAQAQAGKPEED---- 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 887 SIVSLEEEDVTAAAVSAPERATVPAVTVSV---PEGTAAVAAVSSP--EETAPAVAAAITQEGMSAVAGFSPEWAAlait 961
Cdd:pfam03546 95 SESSSEESDSDGETPAAATLTTSPAQVKPLgknSQVRPASTVGKGPsgKGANPAPPGKAGSAAPLVQVGKKEEDSE---- 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 962 vpITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAaavptPEEPTSPAAAVPTPE---------------EP 1026
Cdd:pfam03546 171 --SSSEESDSEGEAPPAATQAKPSGKILQVRPASGPAKGAAPA-----PPQKAGPVATQVKAErskedsesseessdsEE 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1027 TSPAAAVPPPEEP---TSPAAAVPTPEEPTSPAAAVPTPEEPTSP----AAAVPTPEEPTSPAAAVPT--PEEPTSPAAA 1097
Cdd:pfam03546 244 EAPAAATPAQAKPalkTPQTKASPRKGTPITPTSAKVPPVRVGTPapwkAGTVTSPACASSPAVARGAqrPEEDSSSSEE 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1098 VPTPEEPTSPAAAVPT-PEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPA---VPTPEESASAAVAVPTPEESASPA 1173
Cdd:pfam03546 324 SESEEETAPAAAVGQAkSVGKGLQGKAASAPTKGPSGQGTAPVPPGKTGPAVAqvkAEAQEDSESSEEESDSEEAAATPA 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1174 ---AAVPTPAESASFAAVVATleePTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPeeptspaAAVPT 1250
Cdd:pfam03546 404 qvkASGKTPQAKANPAPTKAS---SAKGAASAPGKVVAAAAQAKQGSPAKVKPPARTPQNSAISVRGQ-------ASVPA 473
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2245149928 1251 leepTSSAAAVLTPEElsspAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPT 1315
Cdd:pfam03546 474 ----VGKAVATAAQAQ----KGPVGGPQEEDSESSEEESDSEEEAPAQAKPSGKTPQVRAASAPA 530
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
1003-1193 |
4.43e-17 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 88.38 E-value: 4.43e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1003 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPeeptsPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1082
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPP-----QAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGA 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1083 AAVPTPEePTSPAAAVPTPeeptSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEpafpAPAVPTPEESASAAVA 1162
Cdd:PRK07994 436 TKAKKSE-PAAASRARPVN----SALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVK----KEPVATPKALKKALEH 506
|
170 180 190
....*....|....*....|....*....|.
gi 2245149928 1163 VPTPEESASPAAAvptPAESASFAAVVATLE 1193
Cdd:PRK07994 507 EKTPELAAKLAAE---AIERDPWAALVSQLG 534
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
1029-1302 |
6.27e-17 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 87.67 E-value: 6.27e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1029 PAAAVPPPEeptSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPaaaVPTPeePTSPA 1108
Cdd:PLN03209 324 PSQRVPPKE---SDAADGPKPVPTKPVTPEAPSPPIEEEPPQPKAVVPRPLSPYTAYEDLKPPTSP---IPTP--PSSSP 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1109 AAVPTPEEPASPAaavpTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAavPTPAESASFAAV 1188
Cdd:PLN03209 396 ASSKSVDAVAKPA----EPDVVPSPGSASNVPEVEPAQVEAKKTRPLSPYARYEDLKPPTSPSPTA--PTGVSPSVSSTS 469
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1189 VATLEEPTSPAASvptpaamvatleeFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELS 1268
Cdd:PLN03209 470 SVPAVPDTAPATA-------------ATDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSA 536
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 2245149928 1269 SPAASV-------PTPeEPASPAAAVSNLEEPASPAAAVPT 1302
Cdd:PLN03209 537 PPTALAdeqhhaqPKP-RPLSPYTMYEDLKPPTSPTPSPVL 576
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
811-1333 |
8.98e-17 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 87.82 E-value: 8.98e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 811 EKQVTKAGNTEPVLEEWIP--VLQRP-SRTAAVPTVKDALDA------ALPSPEEGTSIAAVPAPEGTAVVAALVPFPHE 881
Cdd:PHA03378 432 KKKAARTEQPRATPHSQAPtvVLHRPpTQPLEGPTGPLSVQAplepwqPLPHPQVTPVILHQPPAQGVQAHGSMLDLLEK 511
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 882 DILVAsivsleEEDVTAAAVsaPERATVPAVTVSVPEGTAAVAAVSS--PEETAPAVAAAITQEGMSAVA---GFSPEWA 956
Cdd:PHA03378 512 DDEDM------EQRVMATLL--PPSPPQPRAGRRAPCVYTEDLDIESdePASTEPVHDQLLPAPGLGPLQiqpLTSPTTS 583
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 957 ALAITVP--------ITEEDGTPEGPVTPAttvHAPEEPDTAAVRVSTPEEPASPAAAVPTP------EEPTSPAAAVPT 1022
Cdd:PHA03378 584 QLASSAPsyaqtpwpVPHPSQTPEPPTTQS---HIPETSAPRQWPMPLRPIPMRPLRMQPITfnvlvfPTPHQPPQVEIT 660
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1023 PEEPT-SPAAAVPPPEEPTSPAAAVPTPEEPTS--PAAAVPTPeepTSPAAAVPTPEEPtsPAAAvptpEEPTSPAAAVP 1099
Cdd:PHA03378 661 PYKPTwTQIGHIPYQPSPTGANTMLPIQWAPGTmqPPPRAPTP---MRPPAAPPGRAQR--PAAA----TGRARPPAAAP 731
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1100 TPEEPtsPAAAvPTpeePASPAAAVPTpeePASPAAAVPTPEEPAFPAPAVPTPEESASAAvavPTPEESASpAAAVPTP 1179
Cdd:PHA03378 732 GRARP--PAAA-PG---RARPPAAAPG---RARPPAAAPGRARPPAAAPGAPTPQPPPQAP---PAPQQRPR-GAPTPQP 798
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1180 AESASFAAVVATLEEPTSPAAsvptPAAMVATLEEFTSPAASVPTSEEPASL---AAAVSNPEEPTSPAAAV---PTLEE 1253
Cdd:PHA03378 799 PPQAGPTSMQLMPRAAPGQQG----PTKQILRQLLTGGVKRGRPSLKKPAALerqAAAGPTPSPGSGTSDKIvqaPVFYP 874
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1254 PTSSAAAVLTPEELSSPAASVPTPEEPASPAAAvSNLEEPASPaAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVS 1333
Cdd:PHA03378 875 PVLQPIQVMRQLGSVRAAAASTVTQAPTEYTGE-RRGVGPMHP-TDIPPSKRAKTDAYVESQPPHGGQSHSFSVIWENVS 952
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
829-1228 |
1.20e-16 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 87.92 E-value: 1.20e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 829 PVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIV-SLEEEDVTAAAVSAPERA 907
Cdd:PHA03307 41 GQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPArEGSPTPPGPSSPDPPPPT 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 908 TVPAVTV-SVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEdgTPEGPVTPATTVHAPEE 986
Cdd:PHA03307 121 PPPASPPpSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEE--TARAPSSPPAEPPPSTP 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 987 PDTAAVRVSTPEEPASPAAAVPTPEEPTSPAA-AVPTPEEPTSPAAAV----PPPEEPTSPAAAVPTPEEPTSPAAAVPT 1061
Cdd:PHA03307 199 PAAASPRPPRRSSPISASASSPAPAPGRSAADdAGASSSDSSSSESSGcgwgPENECPLPRPAPITLPTRIWEASGWNGP 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1062 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPaaavPTPE 1141
Cdd:PHA03307 279 SSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRS----PSPS 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1142 EPAfPAPAVPTPEESASAAVAVPTPeesaSPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAAS 1221
Cdd:PHA03307 355 RPP-PPADPSSPRKRPRPSRAPSSP----AASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYAR 429
|
410
....*....|
gi 2245149928 1222 VP---TSEEP 1228
Cdd:PHA03307 430 YPlltPSGEP 439
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
1581-1797 |
1.22e-16 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 81.34 E-value: 1.22e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1581 LAKQFHETAEPISDFLSVTEKKLANSEPVGTQTAkIQQQIIRHKALNEEIVNRKKNVDQAIKNGQALLKQTtGEEVLLIQ 1660
Cdd:cd00176 1 KLQQFLRDADELEAWLSEKEELLSSTDYGDDLES-VEALLKKHEALEAELAAHEERVEALNELGEQLIEEG-HPDAEEIQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1661 EKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTyEELTGWLREVEEELAtSGGQSPTGEQIPQFQQRQKELKKEVM 1740
Cdd:cd00176 79 ERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDA-DDLEQWLEEKEAALA-SEDLGKDLESVEELLKKHKELEEELE 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1741 EHRLVLDTVNEVSRALLELVPWRAREGLDKLVSDANEQYKLVSDTIGQRVDEIDAAI 1797
Cdd:cd00176 157 AHEPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
848-1199 |
1.99e-16 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 85.78 E-value: 1.99e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 848 DAALPSPEEGTSiaavpapEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPeRATVPAVTVSVPEGTAAVAAVS 927
Cdd:pfam17823 96 DLSEPATREGAA-------DGAASRALAAAASSSPSSAAQSLPAAIAALPSEAFSAP-RAAACRANASAAPRAAIAAASA 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 928 SPEET-APAVAAAITQEGMSAVAGFSPEWAAlAITVPITEedgTPEGP-VTPAT-TVHAPEEPDTAAVRVSTPEePASPA 1004
Cdd:pfam17823 168 PHAASpAPRTAASSTTAASSTTAASSAPTTA-ASSAPATL---TPARGiSTAATaTGHPAAGTALAAVGNSSPA-AGTVT 242
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1005 AAVPTPEEPT--SPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAavPTPEEPTSPAAAVPTpEEPTSPA 1082
Cdd:pfam17823 243 AAVGTVTPAAlaTLAAAAGTVASAAGTINMGDPHARRLSPAKHMPSDTMARNPAA--PMGAQAQGPIIQVST-DQPVHNT 319
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1083 AAVPTPeEPTSPAAAVPTPEEPTSPAAAVPT-----PEEP-ASPAAAVPT---PEEPASPAAAVPTPEEPAFPA--PAVP 1151
Cdd:pfam17823 320 AGEPTP-SPSNTTLEPNTPKSVASTNLAVVTttkaqAKEPsASPVPVLHTsmiPEVEATSPTTQPSPLLPTQGAagPGIL 398
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 1152 -TPEESASAAV-----AVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPA 1199
Cdd:pfam17823 399 lAPEQVATEATagtasAGPTPRSSGDPKTLAMASCQLSTQGQYLVVTTDPLTPA 452
|
|
| Treacle |
pfam03546 |
Treacher Collins syndrome protein Treacle; |
860-1315 |
2.43e-16 |
|
Treacher Collins syndrome protein Treacle;
Pssm-ID: 460967 [Multi-domain] Cd Length: 531 Bit Score: 85.51 E-value: 2.43e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 860 IAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERAT------VPAVTVSVPEGTAAVAAVSSPEETA 933
Cdd:pfam03546 1 TPATPGKAGPAATQAKAGKPEEDSESSSEEESDSEEETPAAKTPLQAKPsgktpqVRAASAPAKESPRKGAPPVPPGKTG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 934 PAVAAAitQEGM-------SAVAGFSPEWAALAITVPITEEDGTPEGP---VTPATTVHAPEEPDTAAVRVSTPEEPASP 1003
Cdd:pfam03546 81 PAAAQA--QAGKpeedsesSSEESDSDGETPAAATLTTSPAQVKPLGKnsqVRPASTVGKGPSGKGANPAPPGKAGSAAP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1004 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAaavptPEEPTSPAAAVPTPEEPT--SP 1081
Cdd:pfam03546 159 LVQVGKKEEDSESSSEESDSEGEAPPAATQAKPSGKILQVRPASGPAKGAAPA-----PPQKAGPVATQVKAERSKedSE 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1082 AAAVPTPEEPTSPAAAVPTPEEPtspaaAVPTPEEPASPAAAVPtpeepASPAAAVPTPEEPAFPAP----AVPTPEESA 1157
Cdd:pfam03546 234 SSEESSDSEEEAPAAATPAQAKP-----ALKTPQTKASPRKGTP-----ITPTSAKVPPVRVGTPAPwkagTVTSPACAS 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1158 SAAVAVPT--PEESASPAAAVPTPAESASFAAVV---ATLEEPTSPAASVPTPA----AMVATLEEFTSPAAS---VPTS 1225
Cdd:pfam03546 304 SPAVARGAqrPEEDSSSSEESESEEETAPAAAVGqakSVGKGLQGKAASAPTKGpsgqGTAPVPPGKTGPAVAqvkAEAQ 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1226 EEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTpeePASPAAAVSNLEEPASPAAAVPTPEV 1305
Cdd:pfam03546 384 EDSESSEEESDSEEAAATPAQVKASGKTPQAKANPAPTKASSAKGAASAPG---KVVAAAAQAKQGSPAKVKPPARTPQN 460
|
490
....*....|...
gi 2245149928 1306 AAIPA---ASVPT 1315
Cdd:pfam03546 461 SAISVrgqASVPA 473
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
894-1316 |
3.22e-16 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 85.97 E-value: 3.22e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 894 EDVTAAAVSAPERATvpavTVSVPEGTAAVAAVSSP--EETAPAVAAAITQEGMSAVAGFSPEWAAL------AITVPIT 965
Cdd:pfam03154 37 EDLRSSGRNSPSAAS----TSSNDSKAESMKKSSKKikEEAPSPLKSAKRQREKGASDTEEPERATAkksktqEISRPNS 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 966 EEDGtpEGPVTPATTVHapEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPA------AAVPPPEEP 1039
Cdd:pfam03154 113 PSEG--EGESSDGRSVN--DEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQILQTQPPVlqaqsgAASPPSPPP 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1040 TSPAA---AVPTPEEPTSPAAAVPT----PEEPTSPAAA--------------VPTPEEPTSPAAAVPTPeePTSPAAAV 1098
Cdd:pfam03154 189 PGTTQaatAGPTPSAPSVPPQGSPAtsqpPNQTQSTAAPhtliqqtptlhpqrLPSPHPPLQPMTQPPPP--SQVSPQPL 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1099 PTP----EEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPT--PEESASP 1172
Cdd:pfam03154 267 PQPslhgQMPPMPHSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQqpPREQPLP 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1173 AAAVPTPAESASFAAVVATLEEPTS----PAASVPTPAAMVA------TLEEFTSPAASVPTSEEPASLAAAVSNPEEPT 1242
Cdd:pfam03154 347 PAPLSMPHIKPPPTTPIPQLPNPQShkhpPHLSGPSPFQMNSnlppppALKPLSSLSTHHPPSAHPPPLQLMPQSQQLPP 426
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1243 SPAAAvPTLEEPTS---SAAAVLTPEELSSPAASVPTPEE---PASPAAAVSNLEEPASPAAAVPT--PEVAAIPAASVP 1314
Cdd:pfam03154 427 PPAQP-PVLTQSQSlppPAASHPPTSGLHQVPSQSPFPQHpfvPGGPPPITPPSGPPTSTSSAMPGiqPPSSASVSSSGP 505
|
..
gi 2245149928 1315 TP 1316
Cdd:pfam03154 506 VP 507
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
1118-1317 |
3.64e-16 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 85.70 E-value: 3.64e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1118 ASPAAAVPTPEEPASPAAAVPTPeepAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESAsfAAVVATLEEPTS 1197
Cdd:PRK12323 372 AGPATAAAAPVAQPAPAAAAPAA---AAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALA--AARQASARGPGG 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1198 PAASVPTPAAMVATleeftSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAaavltPEELSSPAasvPTP 1277
Cdd:PRK12323 447 APAPAPAPAAAPAA-----AARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEEL-----PPEFASPA---PAQ 513
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2245149928 1278 EEPASPAAAVSNLEEPASPAAAVPTPEVAAIP-AASVPTPE 1317
Cdd:PRK12323 514 PDAAPAGWVAESIPDPATADPDDAFETLAPAPaAAPAPRAA 554
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2067-2239 |
3.73e-16 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 80.18 E-value: 3.73e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2067 ELEKLQPSFEALKRRGEELIgrsqgADKDLAAKEIQDKLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWyDMAALLTT 2146
Cdd:cd00176 48 ELAAHEERVEALNELGEQLI-----EEGHPDAEEIQERLEELNQRWEELRELAEERRQRLEEALDLQQFFR-DADDLEQW 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2147 IKDTQDIVHDLESPGiDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGETEKPEVRKSIDEMNNAWENLNK 2226
Cdd:cd00176 122 LEEKEAALASEDLGK-DLESVEELLKKHKELEEELEAHEPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLE 200
|
170
....*....|...
gi 2245149928 2227 TWKERLEKLEDAM 2239
Cdd:cd00176 201 LAEERQKKLEEAL 213
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
2792-2892 |
5.03e-16 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 76.21 E-value: 5.03e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2792 QFMDALQALVDWLYKVEPQLAeDQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENSRDDTTWVKGQLQ 2871
Cdd:smart00150 2 QFLRDADELEAWLEEKEQLLA-SEDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGHPDAEEIEERLE 80
|
90 100
....*....|....*....|.
gi 2245149928 2872 ELSTRWDTVCKLSVSKQSRLE 2892
Cdd:smart00150 81 ELNERWEELKELAEERRQKLE 101
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
896-1153 |
6.89e-16 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 85.09 E-value: 6.89e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 896 VTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSP---------------EWAALAI 960
Cdd:PRK10811 744 VEETVAAEPVVQEVPAPRTELVKVPLPVVAQTAPEQDEENNAENRDNNGMPRRSRRSPrhlrvsgqrrrryrdERYPTQS 823
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 961 TVPITEEDGTPEG---------PVTPATTVHAPEEPDTAAVrvstPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1031
Cdd:PRK10811 824 PMPLTVACASPEMasgkvwiryPVVRPQDVQVEEQREAEEV----QVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPV 899
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1032 AVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPtspAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1111
Cdd:PRK10811 900 VVAEPQPEEVVVVETTHPEVIAAPVTEQPQVITESDVAVAQEVAEHA---EPVVEPQDETADIEEAAETAEVVVAEPEVV 976
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1112 PTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAF-------------PAPA-VPTP 1153
Cdd:PRK10811 977 AQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEATvehnhatapmtraPAPEyVPEA 1032
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
977-1282 |
8.17e-16 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 85.14 E-value: 8.17e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 977 PATTVHAPEEPDTAAVRVST-------PEEPASPAAAVPTPEEPTS-------PAAAVPTPEEPTSPAA-AVPPPEEPTS 1041
Cdd:PRK10263 309 PLLNGAPITEPVAVAAAATTatqswaaPVEPVTQTPPVASVDVPPAqptvawqPVPGPQTGEPVIAPAPeGYPQQSQYAQ 388
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1042 PAAAVPTPEE---PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPA 1118
Cdd:PRK10263 389 PAVQYNEPLQqpvQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTY 468
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1119 SPAAAVPTPEEPaspaaavPTPEEPAFPAPAVPTPEESASAAVAVPTPEEsASPAAAVPTPAESASFAAVVATLEEPTSP 1198
Cdd:PRK10263 469 QQPAAQEPLYQQ-------PQPVEQQPVVEPEPVVEETKPARPPLYYFEE-VEEKRAREREQLAAWYQPIPEPVKEPEPI 540
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1199 AASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSnpEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPE 1278
Cdd:PRK10263 541 KSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAA--ATVAAPVFSLANSGGPRPQVKEGIGPQLPRPKRIRVPTRR 618
|
....
gi 2245149928 1279 EPAS 1282
Cdd:PRK10263 619 ELAS 622
|
|
| Streccoc_I_II |
NF033804 |
antigen I/II family LPXTG-anchored adhesin; Members of the antigen I/II family are adhesins ... |
994-1178 |
1.03e-15 |
|
antigen I/II family LPXTG-anchored adhesin; Members of the antigen I/II family are adhesins with a glucan-binding domain, two types of repetitive regions, an isopeptide bond-forming domain associated with shear resistance, and a C-terminal LPXTG motif for anchoring to the cell wall. They occur in oral Streptococci, and tend to be major cell surface adhesins. Members of this family include SspA and SspB from Streptococcus gordonii, antigen I/II from S. mutans, etc.
Pssm-ID: 468188 [Multi-domain] Cd Length: 1552 Bit Score: 84.61 E-value: 1.03e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 994 VSTPEEPASPAAAVPTPEEPT--------SPAAAVP--TPEEPTspaaavpPPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1063
Cdd:NF033804 790 MPSDEMPAVPGRDNTEGKKPNiwyslngkIRAVNVPkiTKEKPT-------PPVAPTAPQAPTYEVEKPLEPAPVAPTYE 862
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1064 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAV------ 1137
Cdd:NF033804 863 NEPTPPVKTPDQPEPSKPEEPTYETEKPLEPAPVAPTYENEPTPPVKTPDQPEPSKPEEPTYETEKPLEPAPVApsyene 942
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2245149928 1138 PTPEEPAFPAPAVPTPEESASAAV----AVPTPEESASPaAAVPT 1178
Cdd:NF033804 943 PTPPVKTPDQPEPSKPVEPTYDPLptppVAPTPKQLPTP-PAVPT 986
|
|
| PHA02682 |
PHA02682 |
ORF080 virion core protein; Provisional |
1003-1237 |
1.23e-15 |
|
ORF080 virion core protein; Provisional
Pssm-ID: 177464 [Multi-domain] Cd Length: 280 Bit Score: 80.29 E-value: 1.23e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1003 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAA--VPPPEEPTSPAAAVPTPEEPTSPAAAVPTPeEPTSPAAAVPTPeeptS 1080
Cdd:PHA02682 30 PQATIPAPAAPCPPDADVDPLDKYSVKEAGryYQSRLKANSACMQRPSGQSPLAPSPACAAP-APACPACAPAAP----A 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1081 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPAS-----PAAAVPTPeEPAsPAA-------AVPTPEEPAFPAP 1148
Cdd:PHA02682 105 PAVTCPAPAPACPPATAPTCPPPAVCPAPARPAPACPPStrqcpPAPPLPTP-KPA-PAAkpiflhnQLPPPDYPAASCP 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1149 AVPT-PEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLE-EPTSPAASVPTPAAMV-ATLEEFTS--PAASVP 1223
Cdd:PHA02682 183 TIETaPAASPVLEPRIPDKIIDADNDDKDLIKKELADIADSVRDLNaESLSLTRDIENAKSTTqAAIDDLRRllTGGGVA 262
|
250
....*....|....
gi 2245149928 1224 TSEEPASLAAAVSN 1237
Cdd:PHA02682 263 RRDTPSALRDRVDN 276
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
2682-2784 |
1.34e-15 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 75.06 E-value: 1.34e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2682 QFHEAWKKLIDWLEDAESHLDSElEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTllPEDSQKLDNF 2761
Cdd:smart00150 2 QFLRDADELEAWLEEKEQLLASE-DLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEG--HPDAEEIEER 78
|
90 100
....*....|....*....|...
gi 2245149928 2762 LGEVRDKWDTVCGKSVERQHKLE 2784
Cdd:smart00150 79 LEELNERWEELKELAEERRQKLE 101
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
997-1380 |
1.90e-15 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 83.57 E-value: 1.90e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 997 PEEPAS----PAAAVPTPEEP----TSPAA-AVPTPEEPTSPAAAVPPPE-----EPTSPAAAVPTPEEPTSPAAAVPTP 1062
Cdd:PHA03379 408 ASEPTYgtprPPVEKPRPEVPqsleTATSHgSAQVPEPPPVHDLEPGPLHdqhsmAPCPVAQLPPGPLQDLEPGDQLPGV 487
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1063 EEPTSPAAA-VPTPEEP-TSPAAAVPT--PEEPTSPAAAVPTPEEPTS-PAAAVPTPEEPASPAAAVPTPEEPAS----- 1132
Cdd:PHA03379 488 VQDGRPACApVPAPAGPiVRPWEASLSqvPGVAFAPVMPQPMPVEPVPvPTVALERPVCPAPPLIAMQGPGETSGivrvr 567
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1133 ----PAAAVPTPEEPAFP-----APAVPTPEESA-SAAVAVPTPE-ESASPAAAVPTPAE-------SASFAAVVATLEE 1194
Cdd:PHA03379 568 erwrPAPWTPNPPRSPSQmsvrdRLARLRAEAQPyQASVEVQPPQlTQVSPQQPMEYPLEpeqqmfpGSPFSQVADVMRA 647
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1195 PTSPAASVP----------TPAAMVATLEEFTSPAASVPTSE---------EPASLAAAVSN--PEEPTSPAAAVPTLEE 1253
Cdd:PHA03379 648 GGVPAMQPQyfdlplqqpiSQGAPLAPLRASMGPVPPVPATQpqyfdipltEPINQGASAAHflPQQPMEGPLVPERWMF 727
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1254 PTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVS 1333
Cdd:PHA03379 728 QGATLSQSVRPGVAQSQYFDLPLTQPINHGAPAAHFLHQPPMEGPWVPEQWMFQGAPPSQGTDVVQHQLDALGYVLHVLN 807
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 2245149928 1334 PIGVPflgVSAHTDSVPISEE--GTPVLEEASSTGMWIKEDLDSLVFGI 1380
Cdd:PHA03379 808 HPGVP---VSPAVNQYHVSQAafGLPIDEDESGEGSDTSEPCEALDLSI 853
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
930-1256 |
2.68e-15 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 83.21 E-value: 2.68e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 930 EETAPAVAAA---ITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEepasPAAA 1006
Cdd:PRK10263 279 TYTARGVAADpddVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVD----VPPA 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1007 VPTPEEPTSPaaAVPTPEEPTSPAA-AVPPPEEPTSPAAAVPTPEE---PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1082
Cdd:PRK10263 355 QPTVAWQPVP--GPQTGEPVIAPAPeGYPQQSQYAQPAVQYNEPLQqpvQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQP 432
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1083 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP------ASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEES 1156
Cdd:PRK10263 433 YYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTyqqpaaQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEV 512
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1157 AS---------AAVAVPTPEESASPAAAVPT-PAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSE 1226
Cdd:PRK10263 513 EEkrarereqlAAWYQPIPEPVKEPEPIKSSlKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSG 592
|
330 340 350
....*....|....*....|....*....|
gi 2245149928 1227 EPASLAAAVSNPEEPTSPAAAVPTLEEPTS 1256
Cdd:PRK10263 593 GPRPQVKEGIGPQLPRPKRIRVPTRRELAS 622
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
861-1178 |
3.08e-15 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 82.59 E-value: 3.08e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 861 AAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVS---APERATVPAVTVSVPEGTAAVAAVSSPEETAPAVA 937
Cdd:PRK07003 380 VPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATraeAPPAAPAPPATADRGDDAADGDAPVPAKANARASA 459
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 938 AAITQEGMSAVAGFSPEWAALAITVP--ITEEDGTPEGPVTPATTVHAPEEPDTAAVrvSTPEEPASPAAAvptpeeptS 1015
Cdd:PRK07003 460 DSRCDERDAQPPADSGSASAPASDAPpdAAFEPAPRAAAPSAATPAAVPDARAPAAA--SREDAPAAAAPP--------A 529
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1016 PAAAVPTPeeptspaAAVPPPEEPTSPAAA----------VPTPEEPTSPAAAvptpeeptSPAAAVPTPEEPTSPAAAV 1085
Cdd:PRK07003 530 PEARPPTP-------AAAAPAARAGGAAAAldvlrnagmrVSSDRGARAAAAA--------KPAAAPAAAPKPAAPRVAV 594
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1086 PTPeeptSPAAAVPTPEEPTSPAAavptPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPA---VPTpEESASAAVA 1162
Cdd:PRK07003 595 QVP----TPRARAATGDAPPNGAA----RAEQAAESRGAPPPWEDIPPDDYVPLSADEGFGGPDdgfVPV-FDSGPDDVR 665
|
330
....*....|....*.
gi 2245149928 1163 VpTPEESASPAAAVPT 1178
Cdd:PRK07003 666 V-APKPADAPAPPVDT 680
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
999-1316 |
3.63e-15 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 82.83 E-value: 3.63e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 999 EPASPAAAVPT-------PEEPTSPAAAVPTPEeptspaaavPPPEEPTSPAAAVPTPEEPtSPAAAvPTPEEPTsPAAA 1071
Cdd:PRK10263 318 EPVAVAAAATTatqswaaPVEPVTQTPPVASVD---------VPPAQPTVAWQPVPGPQTG-EPVIA-PAPEGYP-QQSQ 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1072 VPTPEEPTSPAAAVPTPEEPTSPAaavPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVP 1151
Cdd:PRK10263 386 YAQPAVQYNEPLQQPVQPQQPYYA---PAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTY 462
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1152 TPEESASAAVAVPTPEESaspaaavPTPAESASFAAVVATLEEpTSPAASvptPAAMVATLEEftspaasvPTSEEPASL 1231
Cdd:PRK10263 463 QTEQTYQQPAAQEPLYQQ-------PQPVEQQPVVEPEPVVEE-TKPARP---PLYYFEEVEE--------KRAREREQL 523
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1232 AAAVSN-PEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASvpTPEEPASPAAAVSNLEEPA-SPAA-AVPTPEVAAI 1308
Cdd:PRK10263 524 AAWYQPiPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLAS--GVKKATLATGAAATVAAPVfSLANsGGPRPQVKEG 601
|
....*...
gi 2245149928 1309 PAASVPTP 1316
Cdd:PRK10263 602 IGPQLPRP 609
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
1034-1192 |
5.37e-15 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 81.68 E-value: 5.37e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1034 PPPEEPTSPAAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPTPeeptsPAAAVPTPeePTSPAAAVPTPEEPTSPAAAVPT 1113
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEAAAPA-AAPVAQAAAAPAPAAA-----PAAAASAP--AAPPAAAPPAPVAAPAAAAPAAA 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1114 PEEPASPAAAVPTPEEPASP-AAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATL 1192
Cdd:PRK14951 438 PAAAPAAVALAPAPPAQAAPeTVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEGDVWHATVQQLAAAEAITALAREL 517
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
2354-2455 |
5.87e-15 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 73.12 E-value: 5.87e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2354 QFQHALEELMSWLTHTEELLdAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSaGDDASSLRSRL 2433
Cdd:pfam00435 5 QFFRDADDLESWIEEKEALL-SSEDYGKDLESVQALLKKHKALEAELAAHQDRVEALNELAEKLIDEG-HYASEEIQERL 82
|
90 100
....*....|....*....|..
gi 2245149928 2434 EAMNQCWESVLQKTEEREQQLQ 2455
Cdd:pfam00435 83 EELNERWEQLLELAAERKQKLE 104
|
|
| Streccoc_I_II |
NF033804 |
antigen I/II family LPXTG-anchored adhesin; Members of the antigen I/II family are adhesins ... |
1040-1276 |
8.79e-15 |
|
antigen I/II family LPXTG-anchored adhesin; Members of the antigen I/II family are adhesins with a glucan-binding domain, two types of repetitive regions, an isopeptide bond-forming domain associated with shear resistance, and a C-terminal LPXTG motif for anchoring to the cell wall. They occur in oral Streptococci, and tend to be major cell surface adhesins. Members of this family include SspA and SspB from Streptococcus gordonii, antigen I/II from S. mutans, etc.
Pssm-ID: 468188 [Multi-domain] Cd Length: 1552 Bit Score: 81.53 E-value: 8.79e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1040 TSPAAAVPTPEEPTSPAAAVPTPEEPT--------SPAAAVP--TPEEPTSPAAavptpeePTSPAAAVPTPEEPTSPAA 1109
Cdd:NF033804 784 ISATNVMPSDEMPAVPGRDNTEGKKPNiwyslngkIRAVNVPkiTKEKPTPPVA-------PTAPQAPTYEVEKPLEPAP 856
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1110 AVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPaaavptpaesasfaavv 1189
Cdd:NF033804 857 VAPTYENEPTPPVKTPDQPEPSKPEEPTYETEKPLEPAPVAPTYENEPTPPVKTPDQPEPSKP----------------- 919
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1190 atlEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPaslaaavSNPEEPTSPAAavptleePTSSAAAvlTPEELSS 1269
Cdd:NF033804 920 ---EEPTYETEKPLEPAPVAPSYENEPTPPVKTPDQPEP-------SKPVEPTYDPL-------PTPPVAP--TPKQLPT 980
|
....*..
gi 2245149928 1270 PAAsVPT 1276
Cdd:NF033804 981 PPA-VPT 986
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
1039-1229 |
1.32e-14 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 80.85 E-value: 1.32e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1039 PTSPAAAVPTPEEPTSPAAAvptpEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPA 1118
Cdd:PRK10811 846 PVVRPQDVQVEEQREAEEVQ----VQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIA 921
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1119 SPAAAVPTPEEPASPAAAVPTPEEPAfpaPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSP 1198
Cdd:PRK10811 922 APVTEQPQVITESDVAVAQEVAEHAE---PVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVE 998
|
170 180 190
....*....|....*....|....*....|.
gi 2245149928 1199 AASVPTPAAmVATLEEFTspaASVPTSEEPA 1229
Cdd:PRK10811 999 PEVAPAQVP-EATVEHNH---ATAPMTRAPA 1025
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
992-1296 |
1.59e-14 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 80.47 E-value: 1.59e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 992 VRVSTPEEPASPAAAVPTPEEPTSP---------------AAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPA 1056
Cdd:PRK10811 694 AKALNVEEQSVQETEQEERVQQVQPrrkqrqlnqkvrieqSVAEEAVAPVVEETVAAEPVVQEVPAPRTELVKVPLPVVA 773
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1057 AAVPTPEEPTSPAAA----VP-----TPEE----------------PT-SP---AAAVPTPEE---------PTSPAAAV 1098
Cdd:PRK10811 774 QTAPEQDEENNAENRdnngMPrrsrrSPRHlrvsgqrrrryrderyPTqSPmplTVACASPEMasgkvwiryPVVRPQDV 853
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1099 PTPEEPTSPAAAvptpEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPT 1178
Cdd:PRK10811 854 QVEEQREAEEVQ----VQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQ 929
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1179 PAESASfAAVVATLEEPTSPAASVPTPAAMVATLEEfTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSA 1258
Cdd:PRK10811 930 VITESD-VAVAQEVAEHAEPVVEPQDETADIEEAAE-TAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQVP 1007
|
330 340 350
....*....|....*....|....*....|....*...
gi 2245149928 1259 AAVLTPEELSSPAASVPTPEEpASPAAAVSNLEEPASP 1296
Cdd:PRK10811 1008 EATVEHNHATAPMTRAPAPEY-VPEAPRHSDWQRPTFA 1044
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
820-1301 |
1.80e-14 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 80.51 E-value: 1.80e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 820 TEPVLEEWIPVLQRPSRTAAVPTVKDALDAA---LPSPEEGTSIAAVPAPEgtavvaalvpfphedilvasivsleeedv 896
Cdd:PRK10263 300 TQPEYDEYDPLLNGAPITEPVAVAAAATTATqswAAPVEPVTQTPPVASVD----------------------------- 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 897 taAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVT 976
Cdd:PRK10263 351 --VPPAQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQP 428
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 977 PATTVHAPEEPDTAAVRVSTPEEPASPAAAVPT--PEEPTSPAAAVPTPEEPtspaaavPPPEEPTSPAAAVPTPEE--P 1052
Cdd:PRK10263 429 AQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTyqTEQTYQQPAAQEPLYQQ-------PQPVEQQPVVEPEPVVEEtkP 501
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1053 TSP--------------------AAAVPTPEeptsPAAAvPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1112
Cdd:PRK10263 502 ARPplyyfeeveekrarereqlaAWYQPIPE----PVKE-PEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATG 576
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1113 TPEEPASPAAAvptpeePASPAAAVPTPEE---PAFPAPA---VPTPEESASAAVAVPT---PEESA------------- 1170
Cdd:PRK10263 577 AAATVAAPVFS------LANSGGPRPQVKEgigPQLPRPKrirVPTRRELASYGIKLPSqraAEEKAreaqrnqydsgdq 650
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1171 ----------------------------------------------------------------SPAAAVPTPAESASFA 1186
Cdd:PRK10263 651 ynddeidamqqdelarqfaqtqqqrygeqyqhdvpvnaedadaaaeaelarqfaqtqqqrysgeQPAGANPFSLDDFEFS 730
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1187 AVVATLEEptSPAASVPTPAAMvaTLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEE 1266
Cdd:PRK10263 731 PMKALLDD--GPHEPLFTPIVE--PVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQ 806
|
570 580 590
....*....|....*....|....*....|....*
gi 2245149928 1267 LSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVP 1301
Cdd:PRK10263 807 PQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQP 841
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
977-1144 |
2.50e-14 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 79.52 E-value: 2.50e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 977 PATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPeeptsPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPA 1056
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPP-----QAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGA 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1057 AAVPTPEeptsPAAAVPTPeeptsPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAA 1136
Cdd:PRK07994 436 TKAKKSE----PAAASRAR-----PVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEH 506
|
....*...
gi 2245149928 1137 VPTPEEPA 1144
Cdd:PRK07994 507 EKTPELAA 514
|
|
| Drf_FH1 |
pfam06346 |
Formin Homology Region 1; This region is found in some of the Diaphanous related formins (Drfs) ... |
997-1151 |
2.53e-14 |
|
Formin Homology Region 1; This region is found in some of the Diaphanous related formins (Drfs). It consists of low complexity repeats of around 12 residues.
Pssm-ID: 461881 [Multi-domain] Cd Length: 157 Bit Score: 72.98 E-value: 2.53e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 997 PEEPASPAAAVPTPeepTSPAAAVPTPEEPTSPAAAVPPPEEPTSpaAAVPTPeePTSPAAAVPTPEEPTSPAAAVPTPe 1076
Cdd:pfam06346 1 PPPPPLPGDSSTIP---LPPGACIPTPPPLPGGGGPPPPPPLPGS--AAIPPP--PPLPGGTSIPPPPPLPGAASIPPP- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1077 EPTSPAAAVPTPeEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPE--------EPASPAAAVPTPEEPAFPAP 1148
Cdd:pfam06346 73 PPLPGSTGIPPP-PPLPGGAGIPPPPPPLPGGAGVPPPPPPLPGGPGIPPPPpfpggpgiPPPPPGMGMPPPPPFGFGVP 151
|
...
gi 2245149928 1149 AVP 1151
Cdd:pfam06346 152 AAP 154
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
1055-1227 |
2.65e-14 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 79.52 E-value: 2.65e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1055 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPeePTSPAAAVPTPEEPTSPAaavPTPEEPASPAAAVPTPEEPASPA 1134
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPP--QAPAVPPPPASAPQQAPA---VPLPETTSQLLAARQQLQRAQGA 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1135 AAVPTPEEpafPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPaesasfAAVVATLEEPTSPAASVPTPAAMVATLEE 1214
Cdd:PRK07994 436 TKAKKSEP---AAASRARPVNSALERLASVRPAPSALEKAPAKKE------AYRWKATNPVEVKKEPVATPKALKKALEH 506
|
170
....*....|...
gi 2245149928 1215 FTSPAASVPTSEE 1227
Cdd:PRK07994 507 EKTPELAAKLAAE 519
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
1042-1208 |
2.75e-14 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 79.52 E-value: 2.75e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1042 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPeeptsPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPA 1121
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPP-----QAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGA 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1122 AAVPTPEePASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAAS 1201
Cdd:PRK07994 436 TKAKKSE-PAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTPELAA 514
|
....*..
gi 2245149928 1202 VPTPAAM 1208
Cdd:PRK07994 515 KLAAEAI 521
|
|
| PBP1 |
COG5180 |
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ... |
906-1312 |
2.91e-14 |
|
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];
Pssm-ID: 444064 [Multi-domain] Cd Length: 548 Bit Score: 78.95 E-value: 2.91e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 906 RATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPE 985
Cdd:COG5180 15 VPIPPNAARPVLSPELWAAANNDAVSQGDRSALASSPTRPYARKIFEPLDIKLALGKPQLPSVAEPEAYLDPAPPKSSPD 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 986 EPdtAAVRVSTPEEPASPAAAVPtpeePTSPAAAVPTPE---EPTSPAAAVPPPEEPTSPAAAVPTpEEPTSPAAAVPTP 1062
Cdd:COG5180 95 TP--EEQLGAPAGDLLVLPAAKT----PELAAGALPAPAaaaALPKAKVTREATSASAGVALAAAL-LQRSDPILAKDPD 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1063 EEPTS---PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT--PEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAV 1137
Cdd:COG5180 168 GDSAStlpPPAEKLDKVLTEPRDALKDSPEKLDRPKVEVKDeaQEEPPDLTGGADHPRPEAASSPKVDPPSTSEARSRPA 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1138 PTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFA-----------AVVATLEEPTSPAASVPTPA 1206
Cdd:COG5180 248 TVDAQPEMRPPADAKERRRAAIGDTPAAEPPGLPVLEAGSEPQSDAPEAetarpidvkgvASAPPATRPVRPPGGARDPG 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1207 AmvATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAA-AVPTLEEPTSSAA--AVLTPEElsspAASVPTPEEPASP 1283
Cdd:COG5180 328 T--PRPGQPTERPAGVPEAASDAGQPPSAYPPAEEAVPGKpLEQGAPRPGSSGGdgAPFQPPN----GAPQPGLGRRGAP 401
|
410 420
....*....|....*....|....*....
gi 2245149928 1284 AAAVsNLEEPASPAAAVPTPEVAAIPAAS 1312
Cdd:COG5180 402 GPPM-GAGDLVQAALDGGGRETASLGGAA 429
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
1016-1143 |
3.20e-14 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 78.99 E-value: 3.20e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1016 PAAAVPTPeePTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVP--TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1093
Cdd:PRK14951 366 PAAAAEAA--APAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAaaASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPA 443
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1094 PAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEP 1143
Cdd:PRK14951 444 AVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEE 493
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
1003-1139 |
3.80e-14 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 78.99 E-value: 3.80e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1003 PAAAVPTPeePTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1082
Cdd:PRK14951 366 PAAAAEAA--APAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPA 443
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1083 AAVPTPEEPTSPA---AAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPT 1139
Cdd:PRK14951 444 AVALAPAPPAQAApetVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEGDVWHATVQQ 503
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
1071-1312 |
6.79e-14 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 77.69 E-value: 6.79e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1071 AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAv 1150
Cdd:pfam17823 46 AVPRADNKSSEQ*NFCAATAAPAPVTLTKGTSAAHLNSTEVTAEHTPHGTDLSEPATREGAADGAASRALAAAASSSPS- 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1151 pTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSpAASVPTPAAMVATLEEFTSPAASVPT---SEE 1227
Cdd:pfam17823 125 -SAAQSLPAAIAALPSEAFSAPRAAACRANASAAPRAAIAAASAPHA-ASPAPRTAASSTTAASSTTAASSAPTtaaSSA 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1228 PASLAAA---VSNPEEPTSPAAAVPTLEEPTSSAAA--VLTPEELSSPA--ASVPTPEEPASPAAAVSNLEEPA----SP 1296
Cdd:pfam17823 203 PATLTPArgiSTAATATGHPAAGTALAAVGNSSPAAgtVTAAVGTVTPAalATLAAAAGTVASAAGTINMGDPHarrlSP 282
|
250
....*....|....*.
gi 2245149928 1297 AAAVPTPEVAAIPAAS 1312
Cdd:pfam17823 283 AKHMPSDTMARNPAAP 298
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
835-1194 |
7.68e-14 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 78.35 E-value: 7.68e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 835 SRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVtv 914
Cdd:PRK07003 383 PGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASAD-- 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 915 svpegtAAVAAVSSPEETAPAVAAAitqegmsavagfspewAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAvrV 994
Cdd:PRK07003 461 ------SRCDERDAQPPADSGSASA----------------PASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAA--A 516
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 995 STPEEPASPAAAVPTPEEPTsPAAAVPtPEEPTSPAAAV---------------PPPEEPTSPAAAVPTPEEPTSPAAAV 1059
Cdd:PRK07003 517 SREDAPAAAAPPAPEARPPT-PAAAAP-AARAGGAAAALdvlrnagmrvssdrgARAAAAAKPAAAPAAAPKPAAPRVAV 594
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1060 PTPeeptSPAAAVPTPEEPTSPAAAVPTPEEPTSPaaavPTPEEPTSPAAAVP--------------TPEEPASPAAAVP 1125
Cdd:PRK07003 595 QVP----TPRARAATGDAPPNGAARAEQAAESRGA----PPPWEDIPPDDYVPlsadegfggpddgfVPVFDSGPDDVRV 666
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1126 TPEEPASPAAAVPT-PEEPAFPAPAVPTPEESASAAVAVP--------------TPEESASPAAAVPTP--AESASFAAV 1188
Cdd:PRK07003 667 APKPADAPAPPVDTrPLPPAIPLDAIGFDGEWPALAARLPlkgvayqlafnselTAADGGTLKLAVPVPqyADAAQVAKL 746
|
....*.
gi 2245149928 1189 VATLEE 1194
Cdd:PRK07003 747 KAALAD 752
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
998-1130 |
8.28e-14 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 77.83 E-value: 8.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 998 EEPASPAAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPPPEEpTSPAAAVPTPEEPtsPAAAVPTPEEPTSPAAAVPTPEE 1077
Cdd:PRK14951 371 EAAAPAEKKTPARPEAAAPAAA-PVAQAAAAPAPAAAPAAA-ASAPAAPPAAAPP--APVAAPAAAAPAAAPAAAPAAVA 446
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1078 PTSPAAAVPTPEeptspAAAVPTPEEPtSPAAAVPTPEEPASPAAAVPTPEEP 1130
Cdd:PRK14951 447 LAPAPPAQAAPE-----TVAIPVRVAP-EPAVASAAPAPAAAPAAARLTPTEE 493
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
1021-1168 |
1.36e-13 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 75.19 E-value: 1.36e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1021 PTPEEPTSPAAAVPPPEeptsPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA----VPTPEEPTSPAAAVPTPEEPTSPAA 1096
Cdd:NF040712 190 PDFGRPLRPLATVPRLA----REPADARPEEVEPAPAAEGAPATDSDPAEAgtpdDLASARRRRAGVEQPEDEPVGPGAA 265
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1097 AVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAA-AVPTPEEPAFPAPAVPTPEESASAAVAVPTPEE 1168
Cdd:NF040712 266 PAAEPDEATRDAGEPPAPGAAETPEAAEPPAPAPAAPAApAAPEAEEPARPEPPPAPKPKRRRRRASVPSWDD 338
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
817-1133 |
1.40e-13 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 76.54 E-value: 1.40e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 817 AGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPhedilVASIVSLEEEDV 896
Cdd:pfam17823 126 AAQSLPAAIAALPSEAFSAPRAAACRANASAAPRAAIAAASAPHAASPAPRTAASSTTAASST-----TAASSAPTTAAS 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 897 TAAAVSAPERATVPAVTVSV-PEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFspewAALAITVPITEEDGTPEGPV 975
Cdd:pfam17823 201 SAPATLTPARGISTAATATGhPAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATL----AAAAGTVASAAGTINMGDPH 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 976 --TPATTVHAPEepDTAAvrvSTPEEPASPAAAVPTPE----EPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTP 1049
Cdd:pfam17823 277 arRLSPAKHMPS--DTMA---RNPAAPMGAQAQGPIIQvstdQPVHNTAGEPTPSPSNTTLEPNTPKSVASTNLAVVTTT 351
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1050 EEPTSPAAAVPTPEEPTSPAAAVptpeEPTSPAAAvPTPEEPTSPAAAVPTPEEPTSPAAavptpEEPASPAAAVPTPEE 1129
Cdd:pfam17823 352 KAQAKEPSASPVPVLHTSMIPEV----EATSPTTQ-PSPLLPTQGAAGPGILLAPEQVAT-----EATAGTASAGPTPRS 421
|
....
gi 2245149928 1130 PASP 1133
Cdd:pfam17823 422 SGDP 425
|
|
| FimV |
COG3170 |
Type IV pilus assembly protein FimV [Cell motility, Extracellular structures]; |
845-1299 |
1.63e-13 |
|
Type IV pilus assembly protein FimV [Cell motility, Extracellular structures];
Pssm-ID: 442403 [Multi-domain] Cd Length: 508 Bit Score: 76.37 E-value: 1.63e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 845 DALDAALPSPEEGTSIAAVPAPEGTAVV------AALVPFPHEDI--------LVASIVSLEEEDVTAAAVSAPERATV- 909
Cdd:COG3170 43 DSLRVRLASAEAGLRFAVERRADGRPVLrvtssrPVNEPFLDFLVevnwpsgrLVREYTLLLDPPAYAAAAAAPAAAPAp 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 910 ----PAVTVSVPEGTAAVAAVSSPEETAPAVA----AAITQEGMSAVAGFSPEWAALAITV--PITEEDGTPEGPVTPAT 979
Cdd:COG3170 123 apaaPAAAAAAADQPAAEAAPAASGEYYPVRPgdtlWSIAARPVRPSSGVSLDQMMVALYRanPDAFIDGNINRLKAGAV 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 980 TvhapEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAV 1059
Cdd:COG3170 203 L----RVPAAEEVAALSPAEARQEVQAQSADWAAYRARLAAAVEPAPAAAAPAAPPAAAAAAGPVPAAAEDTLSPEVTAA 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1060 PTPEEPTSPAAAvptPEEPTSPAAAVptPEEPTSPAAAVptpeeptspAAAVPTPEEPASPAAAVPTPEEPASPAAAVPT 1139
Cdd:COG3170 279 AAAEEADALPEA---AAELAERLAAL--EAQLAELQRLL---------ALKNPAPAAAVSAPAAAAAAATVEAAAPAAAA 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1140 PEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTspaASVPTPAAMVATLEEFTSPA 1219
Cdd:COG3170 345 QPAAAAPAPALDNPLLLAGLLRRRKAEADEVDPVAEADVYLAYGRDDQAEEILKEAL---ASEPERLDLRLKLLEIYAAR 421
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1220 ASVPTSEEPASLAAAVSNPEEPTSPAAAvptleePTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAA 1299
Cdd:COG3170 422 GDRAAFEALAAELYALTGGGRALDPDNP------LYAPGAAAAAEDAPAAEAEDDSPAEEPAASAAAAAELGDEEGAREL 495
|
|
| PHA03377 |
PHA03377 |
EBNA-3C; Provisional |
854-1292 |
1.65e-13 |
|
EBNA-3C; Provisional
Pssm-ID: 177614 [Multi-domain] Cd Length: 1000 Bit Score: 77.40 E-value: 1.65e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 854 PEEGTSIAAVPAPEGTAV-VAALVPFPHEDILVASIVSLEEEDvTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEET 932
Cdd:PHA03377 482 PQSPPTVAIKPAPPPSRRrRGACVVYDDDIIEVIDVETTEEEE-SVTQPAKPHRKVQDGFQRSGRRQKRATPPKVSPSDR 560
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 933 APAVAA--AITQEGMSAVAGFSPEWAALAITVPIT-EEDGTPEGPVTPATTVHApEEPDTAAVRVSTP------------ 997
Cdd:PHA03377 561 GPPKASppVMAPPSTGPRVMATPSTGPRDMAPPSTgPRQQAKCKDGPPASGPHE-KQPPSSAPRDMAPsvvrmflrerll 639
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 998 EEPASPAA-----------AVPTPEEPTS---PAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAV---- 1059
Cdd:PHA03377 640 EQSTGPKPksfwemragrdGSGIQQEPSSrrqPATQSTPPRPSWLPSVFVLPSVDAGRAQPSEESHLSSMSPTQPIshee 719
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1060 -PTPEEPTSPAAAVPTPEEPTSPAAAVPTP--EEPTSPAAAVPTPEEPTSPAAAVPTPEEPAS--------PAAAVPTPE 1128
Cdd:PHA03377 720 qPRYEDPDDPLDLSLHPDQAPPPSHQAPYSghEEPQAQQAPYPGYWEPRPPQAPYLGYQEPQAqgvqvssyPGYAGPWGL 799
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1129 EPASPA---AAVPTPEEPAF--------PAPAVPTPEESASAAVA---------------VPTPEESASPAAAVPTPAES 1182
Cdd:PHA03377 800 RAQHPRyrhSWAYWSQYPGHghpqgpwaPRPPHLPPQWDGSAGHGqdqvsqfphlqsetgPPRLQLSQVPQLPYSQTLVS 879
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1183 ASfaavvatleeptSPAASVPTPAAmvatleeftsPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVL 1262
Cdd:PHA03377 880 SS------------APSWSSPQPRA----------PIRPIPTRFPPPPMPLQDSMAVGCDSSGTACPSMPFASDYSQGAF 937
|
490 500 510
....*....|....*....|....*....|....
gi 2245149928 1263 TPEELSSPAASVPTPEE----PASPAAAVSNLEE 1292
Cdd:PHA03377 938 TPLDINAQTPKRPRVEEsshgPARCSQATTEAQE 971
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
990-1117 |
1.97e-13 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 76.68 E-value: 1.97e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 990 AAVRVSTPEEPASPAAAVPTPEePTSPAAAVPTPEEPtsPAAAVPPPeePTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1069
Cdd:PRK14951 371 EAAAPAEKKTPARPEAAAPAAA-PVAQAAAAPAPAAA--PAAAASAP--AAPPAAAPPAPVAAPAAAAPAAAPAAAPAAV 445
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2245149928 1070 AAVPTPEEPTSP-AAAVPTPEEPtSPAAAVPTPEEPTSPAAAVPTPEEP 1117
Cdd:PRK14951 446 ALAPAPPAQAAPeTVAIPVRVAP-EPAVASAAPAPAAAPAAARLTPTEE 493
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
977-1206 |
3.17e-13 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 76.23 E-value: 3.17e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 977 PATTVHAPEEPDTAA--VRVSTPEEPASPAAAVPTPEEPtspaAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTS 1054
Cdd:PRK10811 824 PMPLTVACASPEMASgkVWIRYPVVRPQDVQVEEQREAE----EVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPV 899
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1055 PAAAvptpeeptsPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEepaspA 1134
Cdd:PRK10811 900 VVAE---------PQPEEVVVVETTHPEVIAAPVTEQPQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAE-----T 965
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1135 AAVPTPEEPAFPAPAVPTPEESAsAAVAVPTPEESASPAAAVPTPAESASFAavvatleepTSPAASVPTPA 1206
Cdd:PRK10811 966 AEVVVAEPEVVAQPAAPVVAEVA-AEVETVTAVEPEVAPAQVPEATVEHNHA---------TAPMTRAPAPE 1027
|
|
| PksD |
COG3321 |
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ... |
877-1311 |
3.58e-13 |
|
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442550 [Multi-domain] Cd Length: 1386 Bit Score: 76.45 E-value: 3.58e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 877 PFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWA 956
Cdd:COG3321 867 PFQREDAAAALLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLALVALAAAAAALLALA 946
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 957 ALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPP 1036
Cdd:COG3321 947 AAAAAAAAALAAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALLLAAAAAAAALLALAA 1026
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1037 EEPTSPAAAVPTP--------EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1108
Cdd:COG3321 1027 LLAAAAAALAAAAaaaaaaaaLAALAAAAAAAAALALALAALLLLAALAELALAAAALALAAALAAAALALALAALAAAL 1106
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1109 AAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAV 1188
Cdd:COG3321 1107 LLLALLAALALAAAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALLAAAALLLALALALAAALA 1186
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1189 VATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELS 1268
Cdd:COG3321 1187 AALAGLAALLLAALLAALLAALLALALAALAAAAAALLAAAAAAAALALLALAAAAAAVAALAAAAAALLAALAALALLA 1266
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 2245149928 1269 SPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAA 1311
Cdd:COG3321 1267 AAAGLAALAAAAAAAAAALALAAAAAAAAAALAALLAAAAAAA 1309
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
1094-1285 |
3.73e-13 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 75.67 E-value: 3.73e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1094 PAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPeepafPAPAVPTPEESASAAVAVPTPEESASPA 1173
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAP-----QQAPAVPLPETTSQLLAARQQLQRAQGA 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1174 AAVPTPAESASfaavvatleeptSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAavSNPEEPTspaaavptlee 1253
Cdd:PRK07994 436 TKAKKSEPAAA------------SRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKA--TNPVEVK----------- 490
|
170 180 190
....*....|....*....|....*....|..
gi 2245149928 1254 ptssAAAVLTPEELSSPAASVPTPEEPASPAA 1285
Cdd:PRK07994 491 ----KEPVATPKALKKALEHEKTPELAAKLAA 518
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
1081-1268 |
4.10e-13 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 75.67 E-value: 4.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1081 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVptpeePASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAA 1160
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAV-----APPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGA 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1161 VAVPTPEesasPAAAvptpaesasfaavvatleeptSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAA---AVSN 1237
Cdd:PRK07994 436 TKAKKSE----PAAA---------------------SRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKAtnpVEVK 490
|
170 180 190
....*....|....*....|....*....|..
gi 2245149928 1238 PEEPTSPAAAVPTLE-EPTSSAAAVLTPEELS 1268
Cdd:PRK07994 491 KEPVATPKALKKALEhEKTPELAAKLAAEAIE 522
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
950-1104 |
8.73e-13 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 74.37 E-value: 8.73e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 950 GFSP-EWAALAITV----PITEEDGTPEGPVTPATTVHAPEEPDTAAvrvstpeEPASPAAAVPTPEEPtsPAAAVPTPe 1024
Cdd:PRK14951 345 GLAPdEYAALTMVLlrllAFKPAAAAEAAAPAEKKTPARPEAAAPAA-------APVAQAAAAPAPAAA--PAAAASAP- 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1025 ePTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP-AAAVPTPEEPtSPAAAVPTPEEPTSPAAAVPTPEE 1103
Cdd:PRK14951 415 -AAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQAAPeTVAIPVRVAP-EPAVASAAPAPAAAPAAARLTPTE 492
|
.
gi 2245149928 1104 P 1104
Cdd:PRK14951 493 E 493
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
1693-1905 |
9.32e-13 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 70.17 E-value: 9.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1693 KFQSTYEELTGWLREVEEELA-TSGGQSPtgEQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREgLDKL 1771
Cdd:cd00176 4 QFLRDADELEAWLSEKEELLSsTDYGDDL--ESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEE-IQER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1772 VSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAElAWVAETKRKLMALGPIRLEqDQTTAQLQVQKAFSIDIIRH 1851
Cdd:cd00176 81 LEELNQRWEELRELAEERRQRLEEALDLQQFFRDADDLE-QWLEEKEAALASEDLGKDL-ESVEELLKKHKELEEELEAH 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 1852 KDSMDELFSHRSEIFGTCGEEQKTVLQEKTESLIQQYEAISLLNSERYARLERA 1905
Cdd:cd00176 159 EPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEA 212
|
|
| PHA03377 |
PHA03377 |
EBNA-3C; Provisional |
974-1314 |
1.07e-12 |
|
EBNA-3C; Provisional
Pssm-ID: 177614 [Multi-domain] Cd Length: 1000 Bit Score: 74.70 E-value: 1.07e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 974 PVTPaTTVHAPEEPDTAAVRVSTPEEPAsPAAAVPTPEEPtspaaAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPT 1053
Cdd:PHA03377 428 PVKR-TLVKTSGRSDEAEQAQSTPERPG-PSDQPSVPVEP-----AHLTPVEHTTVILHQPPQSPPTVAIKPAPPPSRRR 500
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1054 SPAAAVPTPE-------EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT--PEEPTSPAAAVPTPEEPAS--PAA 1122
Cdd:PHA03377 501 RGACVVYDDDiievidvETTEEEESVTQPAKPHRKVQDGFQRSGRRQKRATPPKvsPSDRGPPKASPPVMAPPSTgpRVM 580
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1123 AVPTPEEP-ASPAAAVPTPEEPAFPAPAVPTPEESA--SAAVAVPTP-------EESASPAAAVPTPaesASFAAVVATL 1192
Cdd:PHA03377 581 ATPSTGPRdMAPPSTGPRQQAKCKDGPPASGPHEKQppSSAPRDMAPsvvrmflRERLLEQSTGPKP---KSFWEMRAGR 657
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1193 EEP--TSPAASVPTPAAMVATLEEFTSPA----ASVPTSEEPASLAAAVS--NPEEPTSPAAAvPTLEEPTSSAAAVLTP 1264
Cdd:PHA03377 658 DGSgiQQEPSSRRQPATQSTPPRPSWLPSvfvlPSVDAGRAQPSEESHLSsmSPTQPISHEEQ-PRYEDPDDPLDLSLHP 736
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 2245149928 1265 EELSSPAASVPTP--EEPASPAAAVSNLEEPASPAA---AVPTPEVAAIPAASVP 1314
Cdd:PHA03377 737 DQAPPPSHQAPYSghEEPQAQQAPYPGYWEPRPPQApylGYQEPQAQGVQVSSYP 791
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
1068-1207 |
1.11e-12 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 73.98 E-value: 1.11e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1068 PAAAVPTPeePTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPA 1147
Cdd:PRK14951 366 PAAAAEAA--APAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPA 443
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1148 PAVPTPEESASAA---VAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAA 1207
Cdd:PRK14951 444 AVALAPAPPAQAApetVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEGDVWHATVQQLAA 506
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
1475-1576 |
1.50e-12 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 66.20 E-value: 1.50e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1475 KFQDALEPLLSWLADTEELIAnQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAElADREKITGQL 1554
Cdd:smart00150 2 QFLRDADELEAWLEEKEQLLA-SEDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGH-PDAEEIEERL 79
|
90 100
....*....|....*....|..
gi 2245149928 1555 ESLESRWTELLSKAAARQKQLE 1576
Cdd:smart00150 80 EELNERWEELKELAEERRQKLE 101
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
2244-2346 |
1.97e-12 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 65.81 E-value: 1.97e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2244 QYQDTLQAMFDWLDNTvIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDetDRDIIREP 2323
Cdd:smart00150 2 QFLRDADELEAWLEEK-EQLLASEDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGHP--DAEEIEER 78
|
90 100
....*....|....*....|...
gi 2245149928 2324 LTELKHLWENLGEKIAHRQHKLE 2346
Cdd:smart00150 79 LEELNERWEELKELAEERRQKLE 101
|
|
| FimV |
COG3170 |
Type IV pilus assembly protein FimV [Cell motility, Extracellular structures]; |
900-1336 |
2.68e-12 |
|
Type IV pilus assembly protein FimV [Cell motility, Extracellular structures];
Pssm-ID: 442403 [Multi-domain] Cd Length: 508 Bit Score: 72.52 E-value: 2.68e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 900 AVSAPERATVPAVTVSvPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEwaalAITVPITE---EDGTPEGPVT 976
Cdd:COG3170 23 ALGEPLRAEIELTDVS-AEEADSLRVRLASAEAGLRFAVERRADGRPVLRVTSSR----PVNEPFLDflvEVNWPSGRLV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 977 PATTVHApeEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPA 1056
Cdd:COG3170 98 REYTLLL--DPPAYAAAAAAPAAAPAPAPAAPAAAAAAADQPAAEAAPAASGEYYPVRPGDTLWSIAARPVRPSSGVSLD 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1057 AAVPTPEEPTsPAA---------------AVPTPEE--PTSPAAAVPTPEEPTSPAAAV---PTPEEPTSPAAAVPTPEE 1116
Cdd:COG3170 176 QMMVALYRAN-PDAfidgninrlkagavlRVPAAEEvaALSPAEARQEVQAQSADWAAYrarLAAAVEPAPAAAAPAAPP 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1117 PASPAAAVPTPEEPA--SPAAAVPTPEEPAFPAPAVPTP-------------EESASAAVAVPTPEESASPAAAVPTPAE 1181
Cdd:COG3170 255 AAAAAAGPVPAAAEDtlSPEVTAAAAAEEADALPEAAAElaerlaaleaqlaELQRLLALKNPAPAAAVSAPAAAAAAAT 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1182 SASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEE-------------PASLAAAV-SNPEEPTSPAAA 1247
Cdd:COG3170 335 VEAAAPAAAAQPAAAAPAPALDNPLLLAGLLRRRKAEADEVDPVAEadvylaygrddqaEEILKEALaSEPERLDLRLKL 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1248 VPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVP 1327
Cdd:COG3170 415 LEIYAARGDRAAFEALAAELYALTGGGRALDPDNPLYAPGAAAAAEDAPAAEAEDDSPAEEPAASAAAAAELGDEEGARE 494
|
....*....
gi 2245149928 1328 PMEEVSPIG 1336
Cdd:COG3170 495 LLEEVLAEG 503
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
971-1135 |
2.75e-12 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 72.98 E-value: 2.75e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 971 PEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAaavPTPEEPTSPAAAVPPPEEPTSPAAAVPTPE 1050
Cdd:PRK07994 366 PEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPA---VPLPETTSQLLAARQQLQRAQGATKAKKSE 442
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1051 eptsPAAAVPTPeeptsPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEP 1130
Cdd:PRK07994 443 ----PAAASRAR-----PVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTPELA 513
|
....*
gi 2245149928 1131 ASPAA 1135
Cdd:PRK07994 514 AKLAA 518
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
900-1108 |
2.82e-12 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 73.15 E-value: 2.82e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 900 AVSAPERAT------VPAVTVSVPEGTAAVAAVSspEETAPAVAAAitqegmsavagfsPEWAALAITVPITEEDGTPEG 973
Cdd:PRK10811 830 ACASPEMASgkvwirYPVVRPQDVQVEEQREAEE--VQVQPVVAEV-------------PVAAAVEPVVSAPVVEAVAEV 894
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 974 PVTPATTvHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPtspAAAVPPPEEPTSPAAAVPTPEEPT 1053
Cdd:PRK10811 895 VEEPVVV-AEPQPEEVVVVETTHPEVIAAPVTEQPQVITESDVAVAQEVAEHA---EPVVEPQDETADIEEAAETAEVVV 970
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1054 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP--------TSPAAAVPTPEEPTSPA 1108
Cdd:PRK10811 971 AEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEatvehnhaTAPMTRAPAPEYVPEAP 1033
|
|
| PRK12727 |
PRK12727 |
flagellar biosynthesis protein FlhF; |
1037-1258 |
2.86e-12 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 237182 [Multi-domain] Cd Length: 559 Bit Score: 72.72 E-value: 2.86e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1037 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA--AVPTP 1114
Cdd:PRK12727 35 AEGIEIVAASNYDEELVQRALETARSDTPATAAAPAPAPQAPTKPAAPVHAPLKLSANANMSQRQRVASAAEDmiAAMAL 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1115 EEPASPAAAVPTPEEPASPAAAVPTPEEPAfPAPAVPTPEESASAAVAVPTPEESASPA-AAVPTPAESASfaAVVATLE 1193
Cdd:PRK12727 115 RQPVSVPRQAPAAAPVRAASIPSPAAQALA-HAAAVRTAPRQEHALSAVPEQLFADFLTtAPVPRAPVQAP--VVAAPAP 191
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1194 EPTSPAAsVPTPAAMVATLEEFTSPA-----ASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSA 1258
Cdd:PRK12727 192 VPAIAAA-LAAHAAYAQDDDEQLDDDgfdldDALPQILPPAALPPIVVAPAAPAALAAVAAAAPAPQNDE 260
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
1125-1267 |
3.40e-12 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 72.44 E-value: 3.40e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1125 PTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVAtlEEPTSPAASVPT 1204
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAA--AAPAAAPAAAPA 443
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1205 PAAMvatleeftSPAASVPTSEEPASLAAAVSnPEEPTSPAAAVPtleePTSSAAAVLTPEEL 1267
Cdd:PRK14951 444 AVAL--------APAPPAQAAPETVAIPVRVA-PEPAVASAAPAP----AAAPAAARLTPTEE 493
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
986-1142 |
3.60e-12 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 70.95 E-value: 3.60e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 986 EPD-TAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1064
Cdd:NF040712 189 DPDfGRPLRPLATVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAA 268
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 1065 PTSPAAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPTPeeptspaAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEE 1142
Cdd:NF040712 269 EPDEATRDAGEPPAPGAAET-PEAAEPPAPAPAAPAA-------PAAPEAEEPARPEPPPAPKPKRRRRRASVPSWDD 338
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
970-1182 |
4.29e-12 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 72.11 E-value: 4.29e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 970 TPEGPVTPATTVHAPEEPDTAAVRV-------STPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSP 1042
Cdd:NF033839 250 NVNTKVEIENTVHKIFADMDAVVTKfkkgltqDTPKEPGNKKPSAPKPGMQPSPQPEKKEVKPEPETPKPEVKPQLEKPK 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1043 AAAVPTPEEP---TSPAAAVPTPE---EPTSPAAAV-PTPEEPTSPAAAVP-TPEEPTSPAAAVPTPE---EPTSPAAAV 1111
Cdd:NF033839 330 PEVKPQPEKPkpeVKPQLETPKPEvkpQPEKPKPEVkPQPEKPKPEVKPQPeTPKPEVKPQPEKPKPEvkpQPEKPKPEV 409
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 1112 -PTPEEP---ASPAAAVPTPEEPASPAAAVPTPE-EPAFPAPAV-PTPEESASAAVAVP-TPEESASPAAAVPTPAES 1182
Cdd:NF033839 410 kPQPEKPkpeVKPQPEKPKPEVKPQPEKPKPEVKpQPEKPKPEVkPQPETPKPEVKPQPeKPKPEVKPQPEKPKPDNS 487
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
1000-1314 |
4.30e-12 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 72.76 E-value: 4.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1000 PASPAAAVPTPEEPTSPAAAVptpEEPTSPaaaVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT 1079
Cdd:PRK10811 689 QAQQEAKALNVEEQSVQETEQ---EERVQQ---VQPRRKQRQLNQKVRIEQSVAEEAVAPVVEETVAAEPVVQEVPAPRT 762
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1080 SPA-AAVPTPEEPTSPAAAVPTPEE--------------------------------PT-SP---AAAVPTPEEpASPAA 1122
Cdd:PRK10811 763 ELVkVPLPVVAQTAPEQDEENNAENrdnngmprrsrrsprhlrvsgqrrrryrderyPTqSPmplTVACASPEM-ASGKV 841
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1123 AVPTPEEPASPAAAVPTPEEPAF-PAPAVPTPEESASAAVAVPTPEESASPAAAVPTpaesasfaAVVATLEEPTSPAAS 1201
Cdd:PRK10811 842 WIRYPVVRPQDVQVEEQREAEEVqVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEP--------VVVAEPQPEEVVVVE 913
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1202 VPTPAAMVATLEEftSPAAsvpTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPE-ELSSPAASVPTPEEP 1280
Cdd:PRK10811 914 TTHPEVIAAPVTE--QPQV---ITESDVAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEpEVVAQPAAPVVAEVA 988
|
330 340 350
....*....|....*....|....*....|....
gi 2245149928 1281 ASPAAAVSnleEPASPAAAVPTPEVAAIPAASVP 1314
Cdd:PRK10811 989 AEVETVTA---VEPEVAPAQVPEATVEHNHATAP 1019
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
1099-1315 |
4.64e-12 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 71.88 E-value: 4.64e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1099 PTPEEPTSPAAAVPTPEEPASPAA-AVPTPEEPASPAAAVPTPEEP--AF---PAPAVPTPEESASAAvavptpeESASP 1172
Cdd:PLN03209 328 VPPKESDAADGPKPVPTKPVTPEApSPPIEEEPPQPKAVVPRPLSPytAYedlKPPTSPIPTPPSSSP-------ASSKS 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1173 AAAVPTPAESASfaavvatleePTSPAASVPTPAAMVATLEEFTspaasvptsEEPASLAAAVSNPEEPTSPAAAVPTLE 1252
Cdd:PLN03209 401 VDAVAKPAEPDV----------VPSPGSASNVPEVEPAQVEAKK---------TRPLSPYARYEDLKPPTSPSPTAPTGV 461
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1253 EPTSSAAAVLTPEELSSPAASV-------PTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPT 1315
Cdd:PLN03209 462 SPSVSSTSSVPAVPDTAPATAAtdaaappPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVK 531
|
|
| PRK12727 |
PRK12727 |
flagellar biosynthesis protein FlhF; |
985-1183 |
4.87e-12 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 237182 [Multi-domain] Cd Length: 559 Bit Score: 71.94 E-value: 4.87e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 985 EEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPE---------------EPTSPAAAVPTP 1049
Cdd:PRK12727 48 EELVQRALETARSDTPATAAAPAPAPQAPTKPAAPVHAPLKLSANANMSQRQRvasaaedmiaamalrQPVSVPRQAPAA 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1050 EEPTSPAAAVPTPEEpTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPTPEEPASPAAaVPTPEE 1129
Cdd:PRK12727 128 APVRAASIPSPAAQA-LAHAAAVRTAPRQEHALSAVPEQLFADFLTTA-PVPRAPVQAPVVAAPAPVPAIAAA-LAAHAA 204
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1130 PASPAAAVPTP---EEPAFPAPAVPtPEESASAAVAVPTPEESASPAAAVPTPAESA 1183
Cdd:PRK12727 205 YAQDDDEQLDDdgfDLDDALPQILP-PAALPPIVVAPAAPAALAAVAAAAPAPQNDE 260
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
2573-2674 |
5.63e-12 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 64.66 E-value: 5.63e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2573 EFQNSLQEFINWLTLAEQSLNiASPPSLILNTVLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFlSQKQDVVLIKNLL 2652
Cdd:smart00150 2 QFLRDADELEAWLEEKEQLLA-SEDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIE-EGHPDAEEIEERL 79
|
90 100
....*....|....*....|..
gi 2245149928 2653 VSVQSRWEKVVQRSIERGRSLD 2674
Cdd:smart00150 80 EELNERWEELKELAEERRQKLE 101
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1059-1317 |
5.82e-12 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 72.66 E-value: 5.82e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1059 VPTPEEPTSPAA----------AVPT--PEEPTSP---AAAVPTPEEPTSPAAA-VPTPEEPTSPAAAVPTPEEPASPAA 1122
Cdd:PHA03247 205 VPSGPGPAAPADltaaalhlygASETylQDEPFVErrvVISHPLRGDIAAPAPPpVVGEGADRAPETARGATGPPPPPEA 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1123 AVPTPEEPASP----AAAVPTPeePAFPAPAVPTPEESASAAVAvpTPEESASPAAAVPTPAESASFAAVVATLEEPT-S 1197
Cdd:PHA03247 285 AAPNGAAAPPDgvwgAALAGAP--LALPAPPDPPPPAPAGDAEE--EDDEDGAMEVVSPLPRPRQHYPLGFPKRRRPTwT 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1198 PAASVPTPAAmvatlEEFTSPAASVPTSEEPASLAAAvsnpeeptSPAAAVPTLEEPTSSAAAVltpeelsspAASVPTP 1277
Cdd:PHA03247 361 PPSSLEDLSA-----GRHHPKRASLPTRKRRSARHAA--------TPFARGPGGDDQTRPAAPV---------PASVPTP 418
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 2245149928 1278 EEPASPAAAvsnleePASPAAAVPTPEvAAIPAASVPTPE 1317
Cdd:PHA03247 419 APTPVPASA------PPPPATPLPSAE-PGSDDGPAPPPE 451
|
|
| PHA02682 |
PHA02682 |
ORF080 virion core protein; Provisional |
960-1110 |
7.09e-12 |
|
ORF080 virion core protein; Provisional
Pssm-ID: 177464 [Multi-domain] Cd Length: 280 Bit Score: 69.12 E-value: 7.09e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 960 ITVPITEEDGTPEGPVTPATTVHAPE---------EPDTAAVRVSTPEEPASPAAAVPTPEEPT-SPAAAVPTPEEPT-S 1028
Cdd:PHA02682 32 ATIPAPAAPCPPDADVDPLDKYSVKEagryyqsrlKANSACMQRPSGQSPLAPSPACAAPAPACpACAPAAPAPAVTCpA 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1029 PAAAVPPPEEPTSPAAAVPTPeePTSPAAAVPTPEEPTSPAAAVPTPEepTSPAA-------AVPTPEeptSPAAAVPTP 1101
Cdd:PHA02682 112 PAPACPPATAPTCPPPAVCPA--PARPAPACPPSTRQCPPAPPLPTPK--PAPAAkpiflhnQLPPPD---YPAASCPTI 184
|
....*....
gi 2245149928 1102 EepTSPAAA 1110
Cdd:PHA02682 185 E--TAPAAS 191
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
857-1207 |
7.30e-12 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 72.28 E-value: 7.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 857 GTSIAAVPAPEGTAVVAALVPFPHEdILVASIVSLEEEDVTA--AAVSAPERA--TVPAVTVSVPEGtaavaAVSSPEET 932
Cdd:PHA03247 199 GAMVFFVPSGPGPAAPADLTAAALH-LYGASETYLQDEPFVErrVVISHPLRGdiAAPAPPPVVGEG-----ADRAPETA 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 933 APAVAAAITQEGMSAVAGFSPE---WAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTA-AVRVSTPEEPASPAAAVP 1008
Cdd:PHA03247 273 RGATGPPPPPEAAAPNGAAAPPdgvWGAALAGAPLALPAPPDPPPPAPAGDAEEEDDEDGAmEVVSPLPRPRQHYPLGFP 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1009 TPEEPT-SPAAAVP--TPEEPTSPAAAVPPPEEPTSPAAAvptpeeptSPAAAVPTPEEPTSPAAAVP-TPEEPTSPAAa 1084
Cdd:PHA03247 353 KRRRPTwTPPSSLEdlSAGRHHPKRASLPTRKRRSARHAA--------TPFARGPGGDDQTRPAAPVPaSVPTPAPTPV- 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1085 vptpeeptsPAAAVPTPEEPTsPAAAVPTPEEPASPAAavPTPEEPASPAAAVPTPE--EPAFPAPAVPTPEESASAAVA 1162
Cdd:PHA03247 424 ---------PASAPPPPATPL-PSAEPGSDDGPAPPPE--RQPPAPATEPAPDDPDDatRKALDALRERRPPEPPGADLA 491
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 2245149928 1163 VPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAA 1207
Cdd:PHA03247 492 ELLGRHPDTAGTVVRLAAREAAIAREVAECSRLTINALRSPFPAS 536
|
|
| Cornifin |
pfam02389 |
Cornifin (SPRR) family; SPRR genes (formerly SPR) encode a novel class of polypeptides (small ... |
993-1127 |
8.22e-12 |
|
Cornifin (SPRR) family; SPRR genes (formerly SPR) encode a novel class of polypeptides (small proline rich proteins) that are strongly induced during differentiation of human epidermal keratinocytes in vitro and in vivo. The most characteriztic feature of the SPRR gene family resides in the structure of the central segments of the encoded polypeptides that are built up from tandemly repeated units of either eight (SPRR1 and SPRR3) or nine (SPRR2) amino acids with the general consensus XKXPEPXX where X is any amino acid. In order to avoid bacterial contamination due to the high polar-nature of the HMM the threshold has been set very high.
Pssm-ID: 280537 [Multi-domain] Cd Length: 135 Bit Score: 65.46 E-value: 8.22e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 993 RVSTPEEPASPAAAVPTPEEPTSPaaAVPTPEEPTSPAAAVPPPEEPTSPaaAVPTPEEPTSPAAAVPTPEEPTSPaaAV 1072
Cdd:pfam02389 4 QVKQPCQPPPQEPCVPTTKEPCHS--KVPEPCNPKVPEPCCPKVPEPCCP--KVPEPCCPKVPEPCCPKVPEPCYP--KV 77
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 2245149928 1073 PTPEEPTSPAAAVPTPEEPTSPaaAVPTPEEPTSPAAAVPTPEEPAsPAAAVPTP 1127
Cdd:pfam02389 78 PEPCSPKVPEPCHPKAPEPCHP--KVPEPCYPKAPEPCQPKVPEPC-PSTVTPGP 129
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
951-1122 |
8.49e-12 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 71.44 E-value: 8.49e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 951 FSPewaALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1030
Cdd:PRK07994 359 FHP---AAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGA 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1031 AAVPPPEePTSPAAAVPTPeeptSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAaavpTPEEPTSPAAA 1110
Cdd:PRK07994 436 TKAKKSE-PAAASRARPVN----SALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVA----TPKALKKALEH 506
|
170
....*....|..
gi 2245149928 1111 VPTPEEPASPAA 1122
Cdd:PRK07994 507 EKTPELAAKLAA 518
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
896-1082 |
9.92e-12 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 71.61 E-value: 9.92e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 896 VTAAAVSAPERATVPAVTVSVPEGTA-AVAAVSSPEETAPAVAAAitqEGMSAVAgfspewAALAITVPITEEDGTPEGP 974
Cdd:PRK10811 850 PQDVQVEEQREAEEVQVQPVVAEVPVaAAVEPVVSAPVVEAVAEV---VEEPVVV------AEPQPEEVVVVETTHPEVI 920
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 975 VTPATTVHAPEEPDTAAVRVSTPE--EPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEP 1052
Cdd:PRK10811 921 AAPVTEQPQVITESDVAVAQEVAEhaEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPE 1000
|
170 180 190
....*....|....*....|....*....|...
gi 2245149928 1053 TSPAAAVPTPEE---PTSPAAAVPTPEEPTSPA 1082
Cdd:PRK10811 1001 VAPAQVPEATVEhnhATAPMTRAPAPEYVPEAP 1033
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
1038-1197 |
1.02e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 70.99 E-value: 1.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1038 EPTSPAAAVPTPEEPTSPAaavptpeeptsPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1117
Cdd:PRK14950 357 EALLVPVPAPQPAKPTAAA-----------PSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTP 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1118 ASPaaavptpeePASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPE-ESASPAAAVPTPAESASFAAVVATLEEPT 1196
Cdd:PRK14950 426 ESA---------PKLTRAAIPVDEKPKYTPPAPPKEEEKALIADGDVLEQlEAIWKQILRDVPPRSPAVQALLSSGVRPV 496
|
.
gi 2245149928 1197 S 1197
Cdd:PRK14950 497 S 497
|
|
| EFh |
cd00051 |
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal ... |
3172-3234 |
1.09e-11 |
|
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to the activation or inactivation of target proteins. EF-hands tend to occur in pairs or higher copy numbers.
Pssm-ID: 238008 [Multi-domain] Cd Length: 63 Bit Score: 62.57 E-value: 1.09e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 3172 RVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAALH 3234
Cdd:cd00051 1 ELREAFRLFDKDGDGTISADELKAALKSLGEGLSEEEIDEMIREVDKDGDGKIDFEEFLELMA 63
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
862-1086 |
1.16e-11 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 71.06 E-value: 1.16e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 862 AVPAPEGTAVVAALVPfphedilvasiVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPeeTAPAVAAAIT 941
Cdd:PRK12323 372 AGPATAAAAPVAQPAP-----------AAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSP--APEALAAARQ 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 942 QEGMSAVAGFSPEWAALAITVPITEED-GTPEGPVTPATTVHAPEEPDTAAVRVST---PEEPASPAAAVPTPEEPT--- 1014
Cdd:PRK12323 439 ASARGPGGAPAPAPAPAAAPAAAARPAaAGPRPVAAAAAAAPARAAPAAAPAPADDdppPWEELPPEFASPAPAQPDaap 518
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1015 SPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSpAAAVP 1086
Cdd:PRK12323 519 AGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPAL-AARLP 589
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
1911-2011 |
1.28e-11 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 63.50 E-value: 1.28e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1911 QFWETYEELSPWIEETRALIAQLPSPAiDHEQLRQQQEEMRQLRESIAEHKPHIDKLLKIGPQLKELNPEEGEMVEEKYQ 1990
Cdd:smart00150 2 QFLRDADELEAWLEEKEQLLASEDLGK-DLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGHPDAEEIEERLE 80
|
90 100
....*....|....*....|.
gi 2245149928 1991 KAENMYAQIKEEVRQRALALD 2011
Cdd:smart00150 81 ELNERWEELKELAEERRQKLE 101
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
1082-1317 |
1.28e-11 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 71.22 E-value: 1.28e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1082 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAA------------------------- 1136
Cdd:PRK10811 734 SVAEEAVAPVVEETVAAEPVVQEVPAPRTELVKVPLPVVAQTAPEQDEENNAENRdnngmprrsrrsprhlrvsgqrrrr 813
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1137 ---------VPTPEEPAFPAPavptpeESASAAVAVPTP---------EESASPAAAVPTPAESASFAAVVATLEEPTSP 1198
Cdd:PRK10811 814 yrderyptqSPMPLTVACASP------EMASGKVWIRYPvvrpqdvqvEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPV 887
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1199 AASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPE 1278
Cdd:PRK10811 888 VEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAETAE 967
|
250 260 270
....*....|....*....|....*....|....*....
gi 2245149928 1279 EPASPAAAVSnlEEPASPAAAVPTPEVAAIPAASVPTPE 1317
Cdd:PRK10811 968 VVVAEPEVVA--QPAAPVVAEVAAEVETVTAVEPEVAPA 1004
|
|
| PRK13108 |
PRK13108 |
prolipoprotein diacylglyceryl transferase; Reviewed |
998-1159 |
1.34e-11 |
|
prolipoprotein diacylglyceryl transferase; Reviewed
Pssm-ID: 237284 [Multi-domain] Cd Length: 460 Bit Score: 70.01 E-value: 1.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 998 EEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPP--PEEPTSP----AAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1071
Cdd:PRK13108 280 EAPGALRGSEYVVDEALEREPAELAAAAVASAASAVGPvgPGEPNQPddvaEAVKAEVAEVTDEVAAESVVQVADRDGES 359
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1072 VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEptspAAAVPTPEEPASPAAAVPTPEEPASPAAAVPT-----PEEPAFP 1146
Cdd:PRK13108 360 TPAVEETSEADIEREQPGDLAGQAPAAHQVDA----EAASAAPEEPAALASEAHDETEPEVPEKAAPIpdpakPDELAVA 435
|
170
....*....|...
gi 2245149928 1147 APAvPTPEESASA 1159
Cdd:PRK13108 436 GPG-DDPAEPDGI 447
|
|
| DUF4045 |
pfam13254 |
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. ... |
963-1228 |
2.04e-11 |
|
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. This domain family is found in bacteria and eukaryotes, and is typically between 384 and 430 amino acids in length.
Pssm-ID: 433066 [Multi-domain] Cd Length: 415 Bit Score: 69.04 E-value: 2.04e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 963 PITEEDGTPEGPVTP------ATTVHA------PEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPaaavPTPEEPTSPA 1030
Cdd:pfam13254 63 TKLSREGSPESTSRPssshseATIVRHskdderPSTPDEGFVKPALPRHSRSSSALSNTGSEEDSP----SLPTSPPSPS 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1031 AAVPP----PEEPTSPAAAVPTPEEPtSPAAAVPTPEEPT--------------------SPAAAVPT--PEEPTSPAAA 1084
Cdd:pfam13254 139 KTMDPkrwsPTKSSWLESALNRPESP-KPKAQPSQPAQPAwmkelnkirqsrasvdlgrpNSFKEVTPvgLMRSPAPGGH 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1085 VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAavPTPEEPAFPAPAVPTPEE-SASAAVAV 1163
Cdd:pfam13254 218 SKSPSVSGISADSSPTKEEPSEEADTLSTDKEQSPAPTSASEPPPKTKELP--KDSEEPAAPSKSAEASTEkKEPDTESS 295
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1164 P-TPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEfTSPAASVPTSEEP 1228
Cdd:pfam13254 296 PeTSSEKSAPSLLSPVSKASIDKPLSSPDRDPLSPKPKPQSPPKDFRANLRS-REVPKDKSKKDEP 360
|
|
| Cornifin |
pfam02389 |
Cornifin (SPRR) family; SPRR genes (formerly SPR) encode a novel class of polypeptides (small ... |
1034-1152 |
2.10e-11 |
|
Cornifin (SPRR) family; SPRR genes (formerly SPR) encode a novel class of polypeptides (small proline rich proteins) that are strongly induced during differentiation of human epidermal keratinocytes in vitro and in vivo. The most characteriztic feature of the SPRR gene family resides in the structure of the central segments of the encoded polypeptides that are built up from tandemly repeated units of either eight (SPRR1 and SPRR3) or nine (SPRR2) amino acids with the general consensus XKXPEPXX where X is any amino acid. In order to avoid bacterial contamination due to the high polar-nature of the HMM the threshold has been set very high.
Pssm-ID: 280537 [Multi-domain] Cd Length: 135 Bit Score: 64.30 E-value: 2.10e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1034 PPPEEPTSPAAAVPT-PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAaaVPTPEEPTSPAAAVPTPEEPTSPAaaVP 1112
Cdd:pfam02389 11 PPPQEPCVPTTKEPChSKVPEPCNPKVPEPCCPKVPEPCCPKVPEPCCPK--VPEPCCPKVPEPCYPKVPEPCSPK--VP 86
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2245149928 1113 TPEEPASPAAAVPTPEEPASPAAavPTPEEPAFPAPAVPT 1152
Cdd:pfam02389 87 EPCHPKAPEPCHPKVPEPCYPKA--PEPCQPKVPEPCPST 124
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
951-1219 |
2.26e-11 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 70.10 E-value: 2.26e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 951 FSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSpAAAVPTPEEPTSPA 1030
Cdd:PHA03378 674 YQPSPTGANTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPA-AAPGRARPPAAAPG 752
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1031 AAVPPPEEPT--SPAAAVPTPEEPTSPAAAVPTP-EEPTSPAAAVPTPEE-PTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1106
Cdd:PHA03378 753 RARPPAAAPGraRPPAAAPGAPTPQPPPQAPPAPqQRPRGAPTPQPPPQAgPTSMQLMPRAAPGQQGPTKQILRQLLTGG 832
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1107 PAAAVPTPEEPAS---PAAAVPTPeEPASPAAAvPTPEEPAFpAPAVPTPEE-----------SASAAVAVPT--PEESA 1170
Cdd:PHA03378 833 VKRGRPSLKKPAAlerQAAAGPTP-SPGSGTSD-KIVQAPVF-YPPVLQPIQvmrqlgsvraaAASTVTQAPTeyTGERR 909
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 2245149928 1171 SPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPA 1219
Cdd:PHA03378 910 GVGPMHPTDIPPSKRAKTDAYVESQPPHGGQSHSFSVIWENVSQGQQQT 958
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
968-1116 |
2.36e-11 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 68.26 E-value: 2.36e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 968 DGTPEGPVTPATTVhAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAA-AVPTPEEPTSPAAAVPPPEEPTSPAAAV 1046
Cdd:NF040712 189 DPDFGRPLRPLATV-PRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTpDDLASARRRRAGVEQPEDEPVGPGAAPA 267
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2245149928 1047 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA-AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1116
Cdd:NF040712 268 AEPDEATRDAGEPPAPGAAETPEAAEPPAPAPAAPAApAAPEAEEPARPEPPPAPKPKRRRRRASVPSWDD 338
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
1107-1251 |
2.72e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 69.74 E-value: 2.72e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1107 PAAAVPtpeEPASPAAAVPTPEEPASPAAAvPTPEEPAFPAPAVPtPEESASAAVAVPTPEESASPAAAVPTPAESASFA 1186
Cdd:PRK14951 366 PAAAAE---AAAPAEKKTPARPEAAAPAAA-PVAQAAAAPAPAAA-PAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAA 440
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2245149928 1187 AVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSeEPASLAAAVSNPEEPTSPAAAVPTL 1251
Cdd:PRK14951 441 APAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAP-AAAPAAARLTPTEEGDVWHATVQQL 504
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
1009-1247 |
2.75e-11 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 69.41 E-value: 2.75e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1009 TPEEPTSPAAAVPTPEEPTSPAaavpPPEEPTSPAAAVPTPEEPTSPaaavPTPEEPTSPAAAVPTPEEPtsPAAAVPTP 1088
Cdd:NF033839 283 TPKEPGNKKPSAPKPGMQPSPQ----PEKKEVKPEPETPKPEVKPQL----EKPKPEVKPQPEKPKPEVK--PQLETPKP 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1089 E---EPTSPAAAV-PTPEEPTSPAAAVP-TPEEPASPAAAVPTPE---EPASPAAAV-PTPEEP---AFPAPAVPTPEES 1156
Cdd:NF033839 353 EvkpQPEKPKPEVkPQPEKPKPEVKPQPeTPKPEVKPQPEKPKPEvkpQPEKPKPEVkPQPEKPkpeVKPQPEKPKPEVK 432
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1157 ASAavavPTPEESASPAAAVPTPaesasfaAVVATLEEPTSPAASVP-TPAAMVATLEEFTSPAASVPTSEEPA-SLAAA 1234
Cdd:NF033839 433 PQP----EKPKPEVKPQPEKPKP-------EVKPQPETPKPEVKPQPeKPKPEVKPQPEKPKPDNSKPQADDKKpSTPNN 501
|
250
....*....|...
gi 2245149928 1235 VSNPEEPTSPAAA 1247
Cdd:NF033839 502 LSKDKQPSNQAST 514
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
1086-1235 |
2.88e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 69.36 E-value: 2.88e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1086 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPT 1165
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAV 445
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1166 PEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATlEEFTSPAASVPTSEEPASLAAAV 1235
Cdd:PRK14951 446 ALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPT-EEGDVWHATVQQLAAAEAITALA 514
|
|
| PRK10905 |
PRK10905 |
cell division protein DamX; Validated |
1005-1197 |
2.99e-11 |
|
cell division protein DamX; Validated
Pssm-ID: 236792 [Multi-domain] Cd Length: 328 Bit Score: 67.66 E-value: 2.99e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1005 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAA--------------AVPTPEEPTSPAAAVPTPEEPTSPAA 1070
Cdd:PRK10905 50 GVQPAPGTTSAEQTAGNTQQDVSLPPISSTPTQGQTPVATdgqqrvevqgdlnnALTQPQNQQQLNNVAVNSTLPTEPAT 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1071 AVPTPEEPTSPAAAVptpeEPTSPAAAVPTPE------EPTSPAAAVPTPEEPAspaAAVPTPEEPASPAAAVPTPEEPA 1144
Cdd:PRK10905 130 VAPVRNGNASRQTAK----TQTAERPATTRPArkqaviEPKKPQATAKTEPKPV---AQTPKRTEPAAPVASTKAPAATS 202
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1145 FPAPAvptpeesasaAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTS 1197
Cdd:PRK10905 203 TPAPK----------ETATTAPVQTASPAQTTATPAAGGKTAGNVGSLKSAPS 245
|
|
| PHA03269 |
PHA03269 |
envelope glycoprotein C; Provisional |
990-1114 |
3.44e-11 |
|
envelope glycoprotein C; Provisional
Pssm-ID: 165527 [Multi-domain] Cd Length: 566 Bit Score: 68.99 E-value: 3.44e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 990 AAVRVSTPEEPASpaaaVPTPEEPTSPAAAVPTPE-EPTSPAAAVP-PPEEPTSPAAAVPTPEE-PTSPAAAVPTPE-EP 1065
Cdd:PHA03269 13 ACINLIIANLNTN----IPIPELHTSAATQKPDPApAPHQAASRAPdPAVAPTSAASRKPDLAQaPTPAASEKFDPApAP 88
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1066 TSPAAAVPTPEE-PTSPAAAVPTPEEP-TSPAAAVPTP-EEPTSPAAAVPTP 1114
Cdd:PHA03269 89 HQAASRAPDPAVaPQLAAAPKPDAAEAfTSAAQAHEAPaDAGTSAASKKPDP 140
|
|
| PHA03369 |
PHA03369 |
capsid maturational protease; Provisional |
998-1317 |
3.60e-11 |
|
capsid maturational protease; Provisional
Pssm-ID: 223061 [Multi-domain] Cd Length: 663 Bit Score: 69.26 E-value: 3.60e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 998 EEPASPAAAVPtpeePTSPAAavptpeeptsPAAAVPPPEEPTSPaaAVPTPEE-PTSPAAAVPTPEEPTSPAAAVPTPE 1076
Cdd:PHA03369 345 NEILKTASLTA----PSRVLA----------AAAKVAVIAAPQTH--TGPADRQrPQRPDGIPYSVPARSPMTAYPPVPQ 408
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1077 EPTSPAAAVPT-PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPAS-PAAAVPTPEEPASPAAA--------------VPTP 1140
Cdd:PHA03369 409 FCGDPGLVSPYnPQSPGTSYGPEPVGPVPPQPTNPYVMPISMANmVYPGHPQEHGHERKRKRggelkeelietlklVKKL 488
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1141 EEPAFPAPAVPTPEESASAAVAVPTPEESASP---AAAVPTPAESASfaavvatlEEPTSPAASVPTPAAMVATLEEF-- 1215
Cdd:PHA03369 489 KEEQESLAKELEATAHKSEIKKIAESEFKNAGaktAAANIEPNCSAD--------AAAPATKRARPETKTELEAVVRFpy 560
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1216 ---TSPAASVPTSEEPASLAAAVSnpEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVptpeEPASPAAavsnLEE 1292
Cdd:PHA03369 561 qirNMESPAFVHSFTSTTLAAAAG--QGSDTAEALAGAIETLLTQASAQPAGLSLPAPAVPV----NASTPAS----TPP 630
|
330 340
....*....|....*....|....*
gi 2245149928 1293 PASPAAavPTPEVAAIPAASVPTPE 1317
Cdd:PHA03369 631 PLAPQE--PPQPGTSAPSLETSLPQ 653
|
|
| PRK12727 |
PRK12727 |
flagellar biosynthesis protein FlhF; |
987-1219 |
7.94e-11 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 237182 [Multi-domain] Cd Length: 559 Bit Score: 68.09 E-value: 7.94e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 987 PDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT 1066
Cdd:PRK12727 24 PDAVILSNRRTAEGIEIVAASNYDEELVQRALETARSDTPATAAAPAPAPQAPTKPAAPVHAPLKLSANANMSQRQRVAS 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1067 SPAA--AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEpTSPAAAVPTPEEPASPAAAVPTPEEPASPA-AAVPtpeEP 1143
Cdd:PRK12727 104 AAEDmiAAMALRQPVSVPRQAPAAAPVRAASIPSPAAQA-LAHAAAVRTAPRQEHALSAVPEQLFADFLTtAPVP---RA 179
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1144 AFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPA 1219
Cdd:PRK12727 180 PVQAPVVAAPAPVPAIAAALAAHAAYAQDDDEQLDDDGFDLDDALPQILPPAALPPIVVAPAAPAALAAVAAAAPA 255
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
1027-1137 |
8.21e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 67.91 E-value: 8.21e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1027 TSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPaaavptpeePTS 1106
Cdd:PRK14950 361 VPVPAPQPAKPTAAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESA---------PKL 431
|
90 100 110
....*....|....*....|....*....|.
gi 2245149928 1107 PAAAVPTPEEPASPAAAVPTPEEPASPAAAV 1137
Cdd:PRK14950 432 TRAAIPVDEKPKYTPPAPPKEEEKALIADGD 462
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
834-1060 |
8.27e-11 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 67.98 E-value: 8.27e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 834 PSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASivsleeedvTAAAVSAPERATVPAVT 913
Cdd:PRK12323 374 PATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRS---------PAPEALAAARQASARGP 444
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 914 VSVPEGTAAVAAVSSPEeTAPAVAAAitqEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDtAAVR 993
Cdd:PRK12323 445 GGAPAPAPAPAAAPAAA-ARPAAAGP---RPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPD-AAPA 519
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2245149928 994 VSTPEEPASPAAAVPTPEEPTS----PAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSpAAAVP 1060
Cdd:PRK12323 520 GWVAESIPDPATADPDDAFETLapapAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPAL-AARLP 589
|
|
| FRQ1 |
COG5126 |
Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]; |
3172-3242 |
9.58e-11 |
|
Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms];
Pssm-ID: 444056 [Multi-domain] Cd Length: 137 Bit Score: 62.12 E-value: 9.58e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2245149928 3172 RVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTklEMTAVADIFDRDGDGYIDYYEFVAALhpnKDAYRP 3242
Cdd:COG5126 70 FARAAFDLLDTDGDGKISADEFRRLLTALGVSEE--EADELFARLDTDGDGKISFEEFVAAV---RDYYTP 135
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
1047-1194 |
1.25e-10 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 65.94 E-value: 1.25e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1047 PTPEEPTSPAAAVPTPEeptsPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPT 1126
Cdd:NF040712 190 PDFGRPLRPLATVPRLA----REPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAA 265
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1127 PEEPASPAAAVPTPEE-----PAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEE 1194
Cdd:NF040712 266 PAAEPDEATRDAGEPPapgaaETPEAAEPPAPAPAAPAAPAAPEAEEPARPEPPPAPKPKRRRRRASVPSWDD 338
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
1037-1177 |
1.37e-10 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 65.94 E-value: 1.37e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1037 EEPTSPAAAVPT-PEEPTSPAAAVPTPEEPtsPAAAVPTPEEPTSPAAA----VPTPEEPTSPAAAVPTPEEPTSPAAAV 1111
Cdd:NF040712 190 PDFGRPLRPLATvPRLAREPADARPEEVEP--APAAEGAPATDSDPAEAgtpdDLASARRRRAGVEQPEDEPVGPGAAPA 267
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1112 PTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPA-PAVPTPEESASAAVAVPTPEESASPAAAVP 1177
Cdd:NF040712 268 AEPDEATRDAGEPPAPGAAETPEAAEPPAPAPAAPAaPAAPEAEEPARPEPPPAPKPKRRRRRASVP 334
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
1001-1116 |
1.46e-10 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 67.14 E-value: 1.46e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1001 ASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPaaavptpeePTS 1080
Cdd:PRK14950 361 VPVPAPQPAKPTAAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESA---------PKL 431
|
90 100 110
....*....|....*....|....*....|....*.
gi 2245149928 1081 PAAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPTPEE 1116
Cdd:PRK14950 432 TRAAIPVDEKPKYTPPA-PPKEEEKALIADGDVLEQ 466
|
|
| FAP |
pfam07174 |
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment ... |
1069-1207 |
1.52e-10 |
|
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment proteins (FAP). Family members are rich in alanine and proline, are approximately 300 long, and seem to be restricted to mycobacteria. These proteins contain a fibronectin-binding motif that allows mycobacteria to bind to fibronectin in the extracellular matrix.
Pssm-ID: 429334 Cd Length: 301 Bit Score: 65.33 E-value: 1.52e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1069 AAAVPTPEepTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPeePASPAAAVPTPEEPAFPAP 1148
Cdd:pfam07174 28 AVAVALPA--VAHADPEPAPPPPSTATAPPAPPPPPPAPAAPAPPPPPAAPNAPNAPPP--PADPNAPPPPPADPNAPPP 103
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1149 AVPTPeeSASAAVAVPTPEESAS---PAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAA 1207
Cdd:pfam07174 104 PAVDP--NAPEPGRIDNAVGGFSyvvPAGWVESDATHLDYGSALLSKTTGQPPEGGQPPPVA 163
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
951-1087 |
1.66e-10 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 67.05 E-value: 1.66e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 951 FSPEWAALAitvPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEP--TSPAAAVPTPEEPTS 1028
Cdd:PRK14951 364 FKPAAAAEA---AAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPapVAAPAAAAPAAAPAA 440
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1029 PAAAVPPPEEPTSPAA----AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1087
Cdd:PRK14951 441 APAAVALAPAPPAQAApetvAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEGDVWHATVQQ 503
|
|
| PHA03269 |
PHA03269 |
envelope glycoprotein C; Provisional |
1005-1127 |
1.68e-10 |
|
envelope glycoprotein C; Provisional
Pssm-ID: 165527 [Multi-domain] Cd Length: 566 Bit Score: 67.06 E-value: 1.68e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1005 AAVPTPeeptspaaaVPTPEEPTSPAAAVPPPE-EPTSPAAAVPTP-EEPTSPAAAVPTPEE-PTSPAAAVPTPE-EPTS 1080
Cdd:PHA03269 20 ANLNTN---------IPIPELHTSAATQKPDPApAPHQAASRAPDPaVAPTSAASRKPDLAQaPTPAASEKFDPApAPHQ 90
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1081 PAAAVPTPEE-PTSPAAAVPTPEEP-TSPAAAVPTP-EEPASPAAAVPTP 1127
Cdd:PHA03269 91 AASRAPDPAVaPQLAAAPKPDAAEAfTSAAQAHEAPaDAGTSAASKKPDP 140
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
959-1334 |
1.73e-10 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 67.40 E-value: 1.73e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 959 AITVPITEEDGTPEGPvtPATTVHAPEEPDTAAVRVSTPEEPASPAAaVPTPEEptspaaavpTPEEPTSPAAavpPPEE 1038
Cdd:PHA03378 554 ASTEPVHDQLLPAPGL--GPLQIQPLTSPTTSQLASSAPSYAQTPWP-VPHPSQ---------TPEPPTTQSH---IPET 618
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1039 PTSPAAAVPTPEEPTSPAAAVPTPEEPtspaAAVPTPEEPTSPAaavPTPEEPT-SPAAAVPTPEEPTSPAAAVPTPEEP 1117
Cdd:PHA03378 619 SAPRQWPMPLRPIPMRPLRMQPITFNV----LVFPTPHQPPQVE---ITPYKPTwTQIGHIPYQPSPTGANTMLPIQWAP 691
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1118 AS--PAAAVPTPeepASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEES-ASPAAAVPTPAESASFAAVVATLEE 1194
Cdd:PHA03378 692 GTmqPPPRAPTP---MRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGrARPPAAAPGRARPPAAAPGRARPPA 768
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1195 PTsPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAA------AVLTPEELS 1268
Cdd:PHA03378 769 AA-PGAPTPQPPPQAPPAPQQRPRGAPTPQPPPQAGPTSMQLMPRAAPGQQGPTKQILRQLLTGGvkrgrpSLKKPAALE 847
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 1269 SPAASVPTPEEPASPAAAVSN---LEEPASPAAAVP-----TPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSP 1334
Cdd:PHA03378 848 RQAAAGPTPSPGSGTSDKIVQapvFYPPVLQPIQVMrqlgsVRAAAASTVTQAPTEYTGERRGVGPMHPTDIPP 921
|
|
| Cornifin |
pfam02389 |
Cornifin (SPRR) family; SPRR genes (formerly SPR) encode a novel class of polypeptides (small ... |
1046-1181 |
2.18e-10 |
|
Cornifin (SPRR) family; SPRR genes (formerly SPR) encode a novel class of polypeptides (small proline rich proteins) that are strongly induced during differentiation of human epidermal keratinocytes in vitro and in vivo. The most characteriztic feature of the SPRR gene family resides in the structure of the central segments of the encoded polypeptides that are built up from tandemly repeated units of either eight (SPRR1 and SPRR3) or nine (SPRR2) amino acids with the general consensus XKXPEPXX where X is any amino acid. In order to avoid bacterial contamination due to the high polar-nature of the HMM the threshold has been set very high.
Pssm-ID: 280537 [Multi-domain] Cd Length: 135 Bit Score: 61.22 E-value: 2.18e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1046 VPTPEEPTSPAAAVPTPEEPTSPAaaVPTPEEPTSPAAAVPTPEEPTSPAaaVPTPEEPTspaaaVPTPEEPASPAAAVP 1125
Cdd:pfam02389 5 VKQPCQPPPQEPCVPTTKEPCHSK--VPEPCNPKVPEPCCPKVPEPCCPK--VPEPCCPK-----VPEPCCPKVPEPCYP 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1126 TPEEPASPAaaVPTPEEPAFPAPAVPTPEESASAAVAVP----TPEesASPAAAVPTPAE 1181
Cdd:pfam02389 76 KVPEPCSPK--VPEPCHPKAPEPCHPKVPEPCYPKAPEPcqpkVPE--PCPSTVTPGPAQ 131
|
|
| PRK13108 |
PRK13108 |
prolipoprotein diacylglyceryl transferase; Reviewed |
983-1157 |
2.36e-10 |
|
prolipoprotein diacylglyceryl transferase; Reviewed
Pssm-ID: 237284 [Multi-domain] Cd Length: 460 Bit Score: 66.16 E-value: 2.36e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 983 APEEPDTAAVRVSTPEEPaSPAAAVPTPEEPTSPAAAVPTPEEPTSP----AAAVPPPEEPTSPAAAVPTPEEPTSPAAA 1058
Cdd:PRK13108 281 APGALRGSEYVVDEALER-EPAELAAAAVASAASAVGPVGPGEPNQPddvaEAVKAEVAEVTDEVAAESVVQVADRDGES 359
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1059 VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEptspAAAVPTPEEPTSPAAAVPTPEEPASP--AAAVPTPEEPASPAAA 1136
Cdd:PRK13108 360 TPAVEETSEADIEREQPGDLAGQAPAAHQVDA----EAASAAPEEPAALASEAHDETEPEVPekAAPIPDPAKPDELAVA 435
|
170 180
....*....|....*....|.
gi 2245149928 1137 VPTPeEPAFPAPAVPTPEESA 1157
Cdd:PRK13108 436 GPGD-DPAEPDGIRRQDDFSS 455
|
|
| PRK12727 |
PRK12727 |
flagellar biosynthesis protein FlhF; |
1011-1240 |
2.61e-10 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 237182 [Multi-domain] Cd Length: 559 Bit Score: 66.17 E-value: 2.61e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1011 EEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA--AVPTP 1088
Cdd:PRK12727 35 AEGIEIVAASNYDEELVQRALETARSDTPATAAAPAPAPQAPTKPAAPVHAPLKLSANANMSQRQRVASAAEDmiAAMAL 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1089 EEPTSPAAAVPTPEEPTSPAAAVPTPEEpASPAAAVPTPEEPASPAAAVPTPEEPAFPA-PAVPTPEESASAAVAVPTpe 1167
Cdd:PRK12727 115 RQPVSVPRQAPAAAPVRAASIPSPAAQA-LAHAAAVRTAPRQEHALSAVPEQLFADFLTtAPVPRAPVQAPVVAAPAP-- 191
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1168 esaSPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEE 1240
Cdd:PRK12727 192 ---VPAIAAALAAHAAYAQDDDEQLDDDGFDLDDALPQILPPAALPPIVVAPAAPAALAAVAAAAPAPQNDEE 261
|
|
| PRK13108 |
PRK13108 |
prolipoprotein diacylglyceryl transferase; Reviewed |
967-1126 |
2.91e-10 |
|
prolipoprotein diacylglyceryl transferase; Reviewed
Pssm-ID: 237284 [Multi-domain] Cd Length: 460 Bit Score: 65.77 E-value: 2.91e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 967 EDGTPE-GPVTPATTVHAPEEPDTAAVRVSTPEEP-ASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAA 1044
Cdd:PRK13108 292 VDEALErEPAELAAAAVASAASAVGPVGPGEPNQPdDVAEAVKAEVAEVTDEVAAESVVQVADRDGESTPAVEETSEADI 371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1045 AVPTPEEPTSPAAAVPTPEEptspAAAVPTPEEPTSPAAAVPTPEEPTSP--AAAVPTPEEPTSPAAAVPTPeEPASPAA 1122
Cdd:PRK13108 372 EREQPGDLAGQAPAAHQVDA----EAASAAPEEPAALASEAHDETEPEVPekAAPIPDPAKPDELAVAGPGD-DPAEPDG 446
|
....
gi 2245149928 1123 AVPT 1126
Cdd:PRK13108 447 IRRQ 450
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
2901-3001 |
3.02e-10 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 59.65 E-value: 3.02e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2901 FRDTVHMLLEWLSEAEQTLRFRGaLPDDTEALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDcITTIKHWIT 2980
Cdd:smart00150 3 FLRDADELEAWLEEKEQLLASED-LGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGHPD-AEEIEERLE 80
|
90 100
....*....|....*....|.
gi 2245149928 2981 IIRARFEEVLTWAKQHQQRLE 3001
Cdd:smart00150 81 ELNERWEELKELAEERRQKLE 101
|
|
| Cornifin |
pfam02389 |
Cornifin (SPRR) family; SPRR genes (formerly SPR) encode a novel class of polypeptides (small ... |
1007-1149 |
3.75e-10 |
|
Cornifin (SPRR) family; SPRR genes (formerly SPR) encode a novel class of polypeptides (small proline rich proteins) that are strongly induced during differentiation of human epidermal keratinocytes in vitro and in vivo. The most characteriztic feature of the SPRR gene family resides in the structure of the central segments of the encoded polypeptides that are built up from tandemly repeated units of either eight (SPRR1 and SPRR3) or nine (SPRR2) amino acids with the general consensus XKXPEPXX where X is any amino acid. In order to avoid bacterial contamination due to the high polar-nature of the HMM the threshold has been set very high.
Pssm-ID: 280537 [Multi-domain] Cd Length: 135 Bit Score: 60.45 E-value: 3.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1007 VPTPEEPTSPAAAVPTPEEPTSPAaaVPPPEEPTSPAAAVPTPEEPTSPAaaVPTPEEPTspaaaVPTPEEPTSPAAAVP 1086
Cdd:pfam02389 5 VKQPCQPPPQEPCVPTTKEPCHSK--VPEPCNPKVPEPCCPKVPEPCCPK--VPEPCCPK-----VPEPCCPKVPEPCYP 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1087 TPEEPTSPAaaVPTPEEPTSPAAAVPTPEEPASPAAavPTPEEPASPAAAVPTpeepAFPAPA 1149
Cdd:pfam02389 76 KVPEPCSPK--VPEPCHPKAPEPCHPKVPEPCYPKA--PEPCQPKVPEPCPST----VTPGPA 130
|
|
| PRK12727 |
PRK12727 |
flagellar biosynthesis protein FlhF; |
918-1170 |
4.08e-10 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 237182 [Multi-domain] Cd Length: 559 Bit Score: 65.78 E-value: 4.08e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 918 EGTAAVAAVSSPEEtapavaaaITQEGMSAVagfSPEWAALAITVPiteedGTPEGPVTPATTVHAPEePDTAAVRVSTP 997
Cdd:PRK12727 36 EGIEIVAASNYDEE--------LVQRALETA---RSDTPATAAAPA-----PAPQAPTKPAAPVHAPL-KLSANANMSQR 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 998 EEPASPAAAVP---TPEEPTSPAAAVPTPEePTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAvPT 1074
Cdd:PRK12727 99 QRVASAAEDMIaamALRQPVSVPRQAPAAA-PVRAASIPSPAAQALAHAAAVRTAPRQEHALSAVPEQLFADFLTTA-PV 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1075 PEEPTSPAAAVPTPEEPTSPAAAvptpeeptsPAAAVPTPEEPASPAAAVPTPEEPASPAAAvPTPEEPAFPAPavPTPE 1154
Cdd:PRK12727 177 PRAPVQAPVVAAPAPVPAIAAAL---------AAHAAYAQDDDEQLDDDGFDLDDALPQILP-PAALPPIVVAP--AAPA 244
|
250
....*....|....*.
gi 2245149928 1155 ESASAAVAVPTPEESA 1170
Cdd:PRK12727 245 ALAAVAAAAPAPQNDE 260
|
|
| PHA03369 |
PHA03369 |
capsid maturational protease; Provisional |
943-1234 |
4.44e-10 |
|
capsid maturational protease; Provisional
Pssm-ID: 223061 [Multi-domain] Cd Length: 663 Bit Score: 65.79 E-value: 4.44e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 943 EGMSAVAGFSPEWAALAITVPitEEDGTPEGPvtpaTTVHAPEEPDTAavrVSTPEEPASPAAAVPTPEEPTSPAAAVPT 1022
Cdd:PHA03369 349 KTASLTAPSRVLAAAAKVAVI--AAPQTHTGP----ADRQRPQRPDGI---PYSVPARSPMTAYPPVPQFCGDPGLVSPY 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1023 peEPTSPAAAVPPPE---EPTSPAAAVPTPEEPTS-PAAAVPTPE-EPTSPAAAVPTPEEPTSPAAAVPTPEE----PTS 1093
Cdd:PHA03369 420 --NPQSPGTSYGPEPvgpVPPQPTNPYVMPISMANmVYPGHPQEHgHERKRKRGGELKEELIETLKLVKKLKEeqesLAK 497
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1094 PAAAVPTPEEPTSPAAAVPTPEEPASPAAAV-PTPEEPASPAAAVPTPEEPAFPAPAV---PTPEESASAAVAVPTPEES 1169
Cdd:PHA03369 498 ELEATAHKSEIKKIAESEFKNAGAKTAAANIePNCSADAAAPATKRARPETKTELEAVvrfPYQIRNMESPAFVHSFTST 577
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1170 ASPAAAVPTPAESASFAAVVATL--------EEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAA 1234
Cdd:PHA03369 578 TLAAAAGQGSDTAEALAGAIETLltqasaqpAGLSLPAPAVPVNASTPASTPPPLAPQEPPQPGTSAPSLETS 650
|
|
| PRK13108 |
PRK13108 |
prolipoprotein diacylglyceryl transferase; Reviewed |
890-1074 |
5.16e-10 |
|
prolipoprotein diacylglyceryl transferase; Reviewed
Pssm-ID: 237284 [Multi-domain] Cd Length: 460 Bit Score: 65.00 E-value: 5.16e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 890 SLEEEDVTAAAVSAPERATVPAVTVSvpeGTAAVAAVSSPEEtaPAVAAAITQEGMSAVAGFSPEWAALAItVPITEEDG 969
Cdd:PRK13108 284 ALRGSEYVVDEALEREPAELAAAAVA---SAASAVGPVGPGE--PNQPDDVAEAVKAEVAEVTDEVAAESV-VQVADRDG 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 970 TPEGpvtpattvhAPEEPDTAAVRVSTPEEPASPAAAVPTPEEptspAAAVPTPEEPTSPAAAVPPPEEPTSP--AAAVP 1047
Cdd:PRK13108 358 ESTP---------AVEETSEADIEREQPGDLAGQAPAAHQVDA----EAASAAPEEPAALASEAHDETEPEVPekAAPIP 424
|
170 180
....*....|....*....|....*..
gi 2245149928 1048 TPEEPTSPAAAVPTPeEPTSPAAAVPT 1074
Cdd:PRK13108 425 DPAKPDELAVAGPGD-DPAEPDGIRRQ 450
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
2134-2236 |
5.41e-10 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 58.88 E-value: 5.41e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2134 EKFWYDMAALLTTIKDTQDIVHDLESPGiDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGEtEKPEVRKS 2213
Cdd:smart00150 1 QQFLRDADELEAWLEEKEQLLASEDLGK-DLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGHP-DAEEIEER 78
|
90 100
....*....|....*....|...
gi 2245149928 2214 IDEMNNAWENLNKTWKERLEKLE 2236
Cdd:smart00150 79 LEELNERWEELKELAEERRQKLE 101
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
987-1103 |
5.58e-10 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 65.22 E-value: 5.58e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 987 PDTAAVRVstPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPaaavptpeePT 1066
Cdd:PRK14950 362 PVPAPQPA--KPTAAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESA---------PK 430
|
90 100 110
....*....|....*....|....*....|....*..
gi 2245149928 1067 SPAAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPTPEE 1103
Cdd:PRK14950 431 LTRAAIPVDEKPKYTPPA-PPKEEEKALIADGDVLEQ 466
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1007-1292 |
5.76e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 66.12 E-value: 5.76e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1007 VPTPEEPTSPAA----------AVPT--PEEPTSP---AAAVPPPEEPTSPAAA-VPTPEEPTSPAAAVPTPEEPTSPAA 1070
Cdd:PHA03247 205 VPSGPGPAAPADltaaalhlygASETylQDEPFVErrvVISHPLRGDIAAPAPPpVVGEGADRAPETARGATGPPPPPEA 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1071 AVPTPEEPTSP----AAAVPTPeePTSPAAAVPTPeePTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFP 1146
Cdd:PHA03247 285 AAPNGAAAPPDgvwgAALAGAP--LALPAPPDPPP--PAPAGDAEEEDDEDGAMEVVSPLPRPRQHYPLGFPKRRRPTWT 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1147 APAVP---TPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLeeftSPAASVP 1223
Cdd:PHA03247 361 PPSSLedlSAGRHHPKRASLPTRKRRSARHAATPFARGPGGDDQTRPAAPVPASVPTPAPTPVPASAPP----PPATPLP 436
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1224 TSEEPASLAAAVSNPEEPTSPA--AAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASP--AAAVSNLEE 1292
Cdd:PHA03247 437 SAEPGSDDGPAPPPERQPPAPAtePAPDDPDDATRKALDALRERRPPEPPGADLAELLGRHPdtAGTVVRLAA 509
|
|
| PRK13108 |
PRK13108 |
prolipoprotein diacylglyceryl transferase; Reviewed |
971-1139 |
5.83e-10 |
|
prolipoprotein diacylglyceryl transferase; Reviewed
Pssm-ID: 237284 [Multi-domain] Cd Length: 460 Bit Score: 65.00 E-value: 5.83e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 971 PEGPVTPAT------TVHAPEEPDTAAVrVSTPEEPASPAAAVPTPEEPTSP----AAAVPTPEEPTSPAAAVPPPEEPT 1040
Cdd:PRK13108 276 PKGREAPGAlrgseyVVDEALEREPAEL-AAAAVASAASAVGPVGPGEPNQPddvaEAVKAEVAEVTDEVAAESVVQVAD 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1041 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEptspAAAVPTPEEPTSPAAAVPTPEEPTSP--AAAVPTPEEPA 1118
Cdd:PRK13108 355 RDGESTPAVEETSEADIEREQPGDLAGQAPAAHQVDA----EAASAAPEEPAALASEAHDETEPEVPekAAPIPDPAKPD 430
|
170 180
....*....|....*....|.
gi 2245149928 1119 SPAAAVPTPeEPASPAAAVPT 1139
Cdd:PRK13108 431 ELAVAGPGD-DPAEPDGIRRQ 450
|
|
| EF-hand_7 |
pfam13499 |
EF-hand domain pair; |
3170-3233 |
6.48e-10 |
|
EF-hand domain pair;
Pssm-ID: 463900 [Multi-domain] Cd Length: 67 Bit Score: 57.65 E-value: 6.48e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 3170 KSRVMDFFRRIDKDQDGKITRQEFIDGI--LASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAAL 3233
Cdd:pfam13499 1 EEKLKEAFKLLDSDGDGYLDVEELKKLLrkLEEGEPLSDEEVEELFKEFDLDKDGRISFEEFLELY 66
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
2462-2565 |
7.46e-10 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 58.50 E-value: 7.46e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2462 QGFHSEIEDFLLELTRMESQLSaSKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLlsRDDSGSGSKTEQ 2541
Cdd:smart00150 1 QQFLRDADELEAWLEEKEQLLA-SEDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLI--EEGHPDAEEIEE 77
|
90 100
....*....|....*....|....
gi 2245149928 2542 SVALLEQKWHVVSSKMEERKSKLE 2565
Cdd:smart00150 78 RLEELNERWEELKELAEERRQKLE 101
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
1144-1311 |
7.47e-10 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 64.89 E-value: 7.47e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1144 AF-PAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASV 1222
Cdd:PRK07994 358 AFhPAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATK 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1223 PTSEEPAslaaavsnPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPT 1302
Cdd:PRK07994 438 AKKSEPA--------AASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKT 509
|
....*....
gi 2245149928 1303 PEVAAIPAA 1311
Cdd:PRK07994 510 PELAAKLAA 518
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
2792-2893 |
7.75e-10 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 58.48 E-value: 7.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2792 QFMDALQALVDWLYKVEPQLAEDQPVHgDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENSRDDTTWVKGQLQ 2871
Cdd:pfam00435 5 QFFRDADDLESWIEEKEALLSSEDYGK-DLESVQALLKKHKALEAELAAHQDRVEALNELAEKLIDEGHYASEEIQERLE 83
|
90 100
....*....|....*....|..
gi 2245149928 2872 ELSTRWDTVCKLSVSKQSRLEQ 2893
Cdd:pfam00435 84 ELNERWEQLLELAAERKQKLEE 105
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
898-1143 |
7.85e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 65.34 E-value: 7.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 898 AAAVSAPERATVPAVTVSVPEGTAAVA---------AVSSPEETAPAVAAAITQEGMSAV--------------AGFS-- 952
Cdd:PHA03247 275 ATGPPPPPEAAAPNGAAAPPDGVWGAAlagaplalpAPPDPPPPAPAGDAEEEDDEDGAMevvsplprprqhypLGFPkr 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 953 --PEWaalaiTVPITEEDGTpegpvtpATTVHAPEEPDTAAVRVSTPEEpASPAAAVPTPEEPTSPAAAVP-TPEEPTSP 1029
Cdd:PHA03247 355 rrPTW-----TPPSSLEDLS-------AGRHHPKRASLPTRKRRSARHA-ATPFARGPGGDDQTRPAAPVPaSVPTPAPT 421
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1030 AAAVPPPEEPTSPaaaVPTPEEPTSPAAAVPTPEEPTSPA--AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP---EEP 1104
Cdd:PHA03247 422 PVPASAPPPPATP---LPSAEPGSDDGPAPPPERQPPAPAtePAPDDPDDATRKALDALRERRPPEPPGADLAEllgRHP 498
|
250 260 270
....*....|....*....|....*....|....*....
gi 2245149928 1105 TSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEP 1143
Cdd:PHA03247 499 DTAGTVVRLAAREAAIAREVAECSRLTINALRSPFPASP 537
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
1008-1124 |
8.06e-10 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 64.83 E-value: 8.06e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1008 PTPEEPTSPAAAVPTPEEPTsPAAAVPPPeeptspaAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPaaavpt 1087
Cdd:PRK14950 363 VPAPQPAKPTAAAPSPVRPT-PAPSTRPK-------AAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESA------ 428
|
90 100 110
....*....|....*....|....*....|....*..
gi 2245149928 1088 peePTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAV 1124
Cdd:PRK14950 429 ---PKLTRAAIPVDEKPKYTPPAPPKEEEKALIADGD 462
|
|
| PRK12727 |
PRK12727 |
flagellar biosynthesis protein FlhF; |
1089-1317 |
9.78e-10 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 237182 [Multi-domain] Cd Length: 559 Bit Score: 64.24 E-value: 9.78e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1089 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPApAVPTPEESASAAVAVpTPEE 1168
Cdd:PRK12727 35 AEGIEIVAASNYDEELVQRALETARSDTPATAAAPAPAPQAPTKPAAPVHAPLKLSANA-NMSQRQRVASAAEDM-IAAM 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1169 SASPAAAVPTPAESAsfaavvatleEPTSpAASVPTPAAMVAtleeftSPAASVPTSEEPASLAAAVsnPEEPTSPAAAV 1248
Cdd:PRK12727 113 ALRQPVSVPRQAPAA----------APVR-AASIPSPAAQAL------AHAAAVRTAPRQEHALSAV--PEQLFADFLTT 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1249 PTLEEPTSSAAAVLTPEELSSPAASVPTPEEPA--------SPAAAVSNLEEPASPAAAVPT-------PEVAAIPAASV 1313
Cdd:PRK12727 174 APVPRAPVQAPVVAAPAPVPAIAAALAAHAAYAqdddeqldDDGFDLDDALPQILPPAALPPivvapaaPAALAAVAAAA 253
|
....
gi 2245149928 1314 PTPE 1317
Cdd:PRK12727 254 PAPQ 257
|
|
| FAP |
pfam07174 |
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment ... |
1004-1094 |
1.03e-09 |
|
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment proteins (FAP). Family members are rich in alanine and proline, are approximately 300 long, and seem to be restricted to mycobacteria. These proteins contain a fibronectin-binding motif that allows mycobacteria to bind to fibronectin in the extracellular matrix.
Pssm-ID: 429334 Cd Length: 301 Bit Score: 62.64 E-value: 1.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1004 AAAVPTPEepTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPeePTSPAAAVPTPEEPTSPAa 1083
Cdd:pfam07174 28 AVAVALPA--VAHADPEPAPPPPSTATAPPAPPPPPPAPAAPAPPPPPAAPNAPNAPPP--PADPNAPPPPPADPNAPP- 102
|
90
....*....|.
gi 2245149928 1084 avPTPEEPTSP 1094
Cdd:pfam07174 103 --PPAVDPNAP 111
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
987-1203 |
1.05e-09 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 64.73 E-value: 1.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 987 PDTAAVRVSTPEEPASPAAAvpTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT 1066
Cdd:PRK08691 364 ASCDANAVIENTELQSPSAQ--TAEKETAAKKPQPRPEAETAQTPVQTASAAAMPSEGKTAGPVSNQENNDVPPWEDAPD 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1067 SPAAAVPTPEeptSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPaSPAAAVPTP-EEPASPAAAVPTPEEPAF 1145
Cdd:PRK08691 442 EAQTAAGTAQ---TSAKSIQTASEAETPPENQVSKNKAADNETDAPLSEVP-SENPIQATPnDEAVETETFAHEAPAEPF 517
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 1146 PAPAVPTPEESASAAVAVPTPE-ESASPAAAVPTPAESasfAAVVATLEEPTSPAASVP 1203
Cdd:PRK08691 518 YGYGFPDNDCPPEDGAEIPPPDwEHAAPADTAGGGADE---EAEAGGIGGNNTPSAPPP 573
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
832-1208 |
1.09e-09 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 64.72 E-value: 1.09e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 832 QRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEdilVASIVSLEEEDVTAAAVSAPERATVPA 911
Cdd:PRK10263 462 YQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEE---VEEKRAREREQLAAWYQPIPEPVKEPE 538
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 912 VTVsvPEGTAAVAAVSSPEETAPAVA--AAITQEGMSAvAGFSPEWAALAITVPiteEDGTPEGPVTPATtvhAPEEPDT 989
Cdd:PRK10263 539 PIK--SSLKAPSVAAVPPVEAAAAVSplASGVKKATLA-TGAAATVAAPVFSLA---NSGGPRPQVKEGI---GPQLPRP 609
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 990 AAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAA------------------VPTPEE 1051
Cdd:PRK10263 610 KRIRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELArqfaqtqqqrygeqyqhdVPVNAE 689
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1052 PTSPAAAVPTPEEPTS----------PAAAVP-----------------TPEEPTSPAAAVP--TPEEPTSPAAAVPTPE 1102
Cdd:PRK10263 690 DADAAAEAELARQFAQtqqqrysgeqPAGANPfslddfefspmkallddGPHEPLFTPIVEPvqQPQQPVAPQQQYQQPQ 769
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1103 EPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESasaavAVPTPEESASPAAAVPTPAES 1182
Cdd:PRK10263 770 QPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQP-----VAPQPQYQQPQQPVAPQPQDT 844
|
410 420 430
....*....|....*....|....*....|....*
gi 2245149928 1183 ASFAAVVAT-----LEEPTSPAASV----PTPAAM 1208
Cdd:PRK10263 845 LLHPLLMRNgdsrpLHKPTTPLPSLdlltPPPSEV 879
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
1086-1253 |
1.21e-09 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 63.25 E-value: 1.21e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1086 PTPEEPTSPAAAVPTPEeptsPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPT 1165
Cdd:NF040712 190 PDFGRPLRPLATVPRLA----REPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAA 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1166 PEESASPAAAVPTPAEsasfAAVVATLEEPTSPAASVPTPAAmvatleeftspAASVPTSEEPASLAAAVSNPEEPTSPA 1245
Cdd:NF040712 266 PAAEPDEATRDAGEPP----APGAAETPEAAEPPAPAPAAPA-----------APAAPEAEEPARPEPPPAPKPKRRRRR 330
|
....*...
gi 2245149928 1246 AAVPTLEE 1253
Cdd:NF040712 331 ASVPSWDD 338
|
|
| PRK14949 |
PRK14949 |
DNA polymerase III subunits gamma and tau; Provisional |
911-1315 |
1.22e-09 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237863 [Multi-domain] Cd Length: 944 Bit Score: 64.36 E-value: 1.22e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 911 AVTVSVPEGTAAVAAVSSPEETAPAVAAAITQ---EGMSAVAGFSPEWAAL--AITVPITEEDGTPEGPVTPATTVHAPE 985
Cdd:PRK14949 371 PAEISLPEGQTPSALAAAVQAPHANEPQFVNAapaEKKTALTEQTTAQQQVqaANAEAVAEADASAEPADTVEQALDDES 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 986 EPDTA-----AVRVSTPE----EPASPAAAVPTpeepTSPAAAVPTPEEPTSPAAAVPPPEEPTSpaAAVPTPEEPTSPA 1056
Cdd:PRK14949 451 ELLAAlnaeqAVILSQAQsqgfEASSSLDADNS----AVPEQIDSTAEQSVVNPSVTDTQVDDTS--ASNNSAADNTVDD 524
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1057 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPeePASPAAAVPTPEEPASPAAA 1136
Cdd:PRK14949 525 NYSAEDTLESNGLDEGDYAQDSAPLDAYQDDYVAFSSESYNALSDDEQHSANVQSAQS--AAEAQPSSQSLSPISAVTTA 602
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1137 VPTPEEPAFpAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFT 1216
Cdd:PRK14949 603 AASLADDDI-LDAVLAARDSLLSDLDALSPKEGDGKKSSADRKPKTPPSRAPPASLSKPASSPDASQTSASFDLDPDFEL 681
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1217 SPAASVPTSEEPASLAAAVSNPEEPtspaAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPAS- 1295
Cdd:PRK14949 682 ATHQSVPEAALASGSAPAPPPVPDP----YDRPPWEEAPEVASANDGPNNAAEGNLSESVEDASNSELQAVEQQATHQPq 757
|
410 420
....*....|....*....|.
gi 2245149928 1296 -PAAAVPTPEVAAIPAASVPT 1315
Cdd:PRK14949 758 vQAEAQSPASTTALTQTSSEV 778
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
997-1085 |
1.23e-09 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 64.53 E-value: 1.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 997 PEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1076
Cdd:PRK12270 38 PGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDEV 117
|
90
....*....|
gi 2245149928 1077 EP-TSPAAAV 1085
Cdd:PRK12270 118 TPlRGAAAAV 127
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1437-2137 |
1.32e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 64.69 E-value: 1.32e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1437 DVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALlhcGKFQDALEPLLSWLADTEELIANQKPPSAEYKVVKAQIQEQKL 1516
Cdd:TIGR02168 296 EISRLEQQKQILRERLANLERQLEELEAQLEELE---SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELES 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1517 LQRLLDDrkatvdmlQAEGGRIAQSAELADREKITGQLESLESRWTEL---LSKAAARQKQLEDILVLAkQFHETAEPIS 1593
Cdd:TIGR02168 373 RLEELEE--------QLETLRSKVAQLELQIASLNNEIERLEARLERLedrRERLQQEIEELLKKLEEA-ELKELQAELE 443
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1594 DFLSVTEKKLANSEPVGTQTAKIQQQIirhkALNEEIVNRKKNVDQAIKNGQALLKQTTGE---------EVLLIQEKLD 1664
Cdd:TIGR02168 444 ELEEELEELQEELERLEEALEELREEL----EEAEQALDAAERELAQLQARLDSLERLQENlegfsegvkALLKNQSGLS 519
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1665 GIKTRYAD-ITVTSSkalrtLEQARQLAtkfqstyeeltgwLREVEEELATSGgqSPTGEQIPQFQQRQKELKKEVMEHR 1743
Cdd:TIGR02168 520 GILGVLSElISVDEG-----YEAAIEAA-------------LGGRLQAVVVEN--LNAAKKAIAFLKQNELGRVTFLPLD 579
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1744 LVLDTVNEVSRALLELVPWRAREGLDKLVSDANEQYKLVSDTIGQR--VDEIDAAIQRSQQYeqaaDAELAWVAETKRKL 1821
Cdd:TIGR02168 580 SIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvVDDLDNALELAKKL----RPGYRIVTLDGDLV 655
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1822 MALGPIRLEQDQTTAQLQVQKAfsidiirhkdsmdELFSHRSEIfgtcgEEQKTVLQEKTESLIQQYEAISLLNSERYAR 1901
Cdd:TIGR02168 656 RPGGVITGGSAKTNSSILERRR-------------EIEELEEKI-----EELEEKIAELEKALAELRKELEELEEELEQL 717
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1902 LERAQVLVNQFWETYEELSPWIEETRALIAQLPSPAIDHEQLRQQQEEMRQLRESIAEH-KPHIDKLLKIGPQLKELNpE 1980
Cdd:TIGR02168 718 RKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEElAEAEAEIEELEAQIEQLK-E 796
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1981 EGEMVEEKYQKAENMYAQIKEEVRQRALALD----EAVSQSTQITEFHDKIEPMLETLENLSSRLRmpplipAEVDKIRE 2056
Cdd:TIGR02168 797 ELKALREALDELRAELTLLNEEAANLRERLEslerRIAATERRLEDLEEQIEELSEDIESLAAEIE------ELEELIEE 870
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2057 CISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKdlAAKEIQDKLDQMvffwEDIKARAEEREIKF-LDVLELAEK 2135
Cdd:TIGR02168 871 LESELEALLNERASLEEALALLRSELEELSEELRELES--KRSELRRELEEL----REKLAQLELRLEGLeVRIDNLQER 944
|
..
gi 2245149928 2136 FW 2137
Cdd:TIGR02168 945 LS 946
|
|
| PRK13108 |
PRK13108 |
prolipoprotein diacylglyceryl transferase; Reviewed |
953-1113 |
1.36e-09 |
|
prolipoprotein diacylglyceryl transferase; Reviewed
Pssm-ID: 237284 [Multi-domain] Cd Length: 460 Bit Score: 63.46 E-value: 1.36e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 953 PEWAALAITVPITEEDGTPegPVTPATtvhaPEEPD-TAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1031
Cdd:PRK13108 298 REPAELAAAAVASAASAVG--PVGPGE----PNQPDdVAEAVKAEVAEVTDEVAAESVVQVADRDGESTPAVEETSEADI 371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1032 AVPPPEEPTSPAAAVPTPEEptspAAAVPTPEEPTSPAAAVPTPEEPTSP--AAAVPTPEEPTSPAAAVPTPeEPTSPAA 1109
Cdd:PRK13108 372 EREQPGDLAGQAPAAHQVDA----EAASAAPEEPAALASEAHDETEPEVPekAAPIPDPAKPDELAVAGPGD-DPAEPDG 446
|
....
gi 2245149928 1110 AVPT 1113
Cdd:PRK13108 447 IRRQ 450
|
|
| PHA03269 |
PHA03269 |
envelope glycoprotein C; Provisional |
1044-1239 |
1.37e-09 |
|
envelope glycoprotein C; Provisional
Pssm-ID: 165527 [Multi-domain] Cd Length: 566 Bit Score: 63.98 E-value: 1.37e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1044 AAVPTPeeptspaaaVPTPEEPTSPAAAVPTPE-EPTSPAAAVPTP-EEPTSPAAAVPTPEE-PTSPAAAVPTPeEPASP 1120
Cdd:PHA03269 20 ANLNTN---------IPIPELHTSAATQKPDPApAPHQAASRAPDPaVAPTSAASRKPDLAQaPTPAASEKFDP-APAPH 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1121 AAAVPTPEEPASP-AAAVPTPeEPAFPAPAVPTPEEsASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPA 1199
Cdd:PHA03269 90 QAASRAPDPAVAPqLAAAPKP-DAAEAFTSAAQAHE-APADAGTSAASKKPDPAAHTQHSPPPFAYTRSMEHIACTHGGI 167
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2245149928 1200 ASVPT--PAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPE 1239
Cdd:PHA03269 168 QFIPYfhKFILPCYLQIFTGQGAAFKQHELPKTYEEDFLDPE 209
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
1102-1202 |
1.48e-09 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 64.53 E-value: 1.48e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1102 EEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV-PTPEESASAAVAVPTPEESASPAAAVPTPA 1180
Cdd:PRK12270 34 ADYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAApPKPAAAAAAAAAPAAPPAAAAAAAPAAAAV 113
|
90 100 110
....*....|....*....|....*....|..
gi 2245149928 1181 ESAS------FAAVV----ATLEEPTspAASV 1202
Cdd:PRK12270 114 EDEVtplrgaAAAVAknmdASLEVPT--ATSV 143
|
|
| PHA02682 |
PHA02682 |
ORF080 virion core protein; Provisional |
1094-1379 |
1.72e-09 |
|
ORF080 virion core protein; Provisional
Pssm-ID: 177464 [Multi-domain] Cd Length: 280 Bit Score: 61.80 E-value: 1.72e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1094 PAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAV--PTPEEPAFPAPAVPTPeesasaAVAVPTPeesaS 1171
Cdd:PHA02682 30 PQATIPAPAAPCPPDADVDPLDKYSVKEAGRYYQSRLKANSACMqrPSGQSPLAPSPACAAP------APACPAC----A 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1172 PAAavPTPAesasfaavvatleePTSPAasvPTPAAmvatleeftsPAASVPTSEEPASLAAavsnpeePTSPAAAVPtl 1251
Cdd:PHA02682 100 PAA--PAPA--------------VTCPA---PAPAC----------PPATAPTCPPPAVCPA-------PARPAPACP-- 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1252 eePTSSAAavltpeelsSPAASVPTPE--EPASPAAAVSNLEEPASPAAAVPTPEVAaiPAAS------VPTPEVPAIPA 1323
Cdd:PHA02682 142 --PSTRQC---------PPAPPLPTPKpaPAAKPIFLHNQLPPPDYPAASCPTIETA--PAASpvleprIPDKIIDADND 208
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1324 AAVPPMEEVSPIGVPFLGVSAHTDSVpiseegTPVLEEASSTGMWIKEDLDSLVFG 1379
Cdd:PHA02682 209 DKDLIKKELADIADSVRDLNAESLSL------TRDIENAKSTTQAAIDDLRRLLTG 258
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
1072-1177 |
1.75e-09 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 64.14 E-value: 1.75e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1072 VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVP 1151
Cdd:PRK12270 38 PGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDEV 117
|
90 100 110
....*....|....*....|....*....|....
gi 2245149928 1152 TPEESASAAVA--------VPTpeesASPAAAVP 1177
Cdd:PRK12270 118 TPLRGAAAAVAknmdasleVPT----ATSVRAVP 147
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
1151-1363 |
1.81e-09 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 63.41 E-value: 1.81e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1151 PTPEESASAAVAVPTPEESASPAAavPTPAESasfaavvatlEEPTSPAASVPTPAAMVATLEEF---TSPAASVPTSEE 1227
Cdd:PLN03209 328 VPPKESDAADGPKPVPTKPVTPEA--PSPPIE----------EEPPQPKAVVPRPLSPYTAYEDLkppTSPIPTPPSSSP 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1228 PASLAA-AVSNPEEPTSPAAAVPTLEEPTSSAAAV-------LTP----EELSSPAASVPTPEEPASPAAAVSNlEEPAS 1295
Cdd:PLN03209 396 ASSKSVdAVAKPAEPDVVPSPGSASNVPEVEPAQVeakktrpLSPyaryEDLKPPTSPSPTAPTGVSPSVSSTS-SVPAV 474
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 1296 PAAAVPTPEV-AAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEAS 1363
Cdd:PLN03209 475 PDTAPATAATdAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALAD 543
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
1023-1111 |
2.08e-09 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 63.76 E-value: 2.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1023 PEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1102
Cdd:PRK12270 38 PGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDEV 117
|
90
....*....|
gi 2245149928 1103 EP-TSPAAAV 1111
Cdd:PRK12270 118 TPlRGAAAAV 127
|
|
| PHA03269 |
PHA03269 |
envelope glycoprotein C; Provisional |
979-1105 |
2.35e-09 |
|
envelope glycoprotein C; Provisional
Pssm-ID: 165527 [Multi-domain] Cd Length: 566 Bit Score: 63.21 E-value: 2.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 979 TTVHAPEEPDTAAVRVSTPE-EPASPAAAVPTP-EEPTSPAAAVPTPEE-PTSPAAAVPPPE-EPTSPAAAVPTPEE-PT 1053
Cdd:PHA03269 24 TNIPIPELHTSAATQKPDPApAPHQAASRAPDPaVAPTSAASRKPDLAQaPTPAASEKFDPApAPHQAASRAPDPAVaPQ 103
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 1054 SPAAAVPTPEEP-TSPAAAVPTP-EEPTSPAAAVPTpeeptsPAAAVPTPEEPT 1105
Cdd:PHA03269 104 LAAAPKPDAAEAfTSAAQAHEAPaDAGTSAASKKPD------PAAHTQHSPPPF 151
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
1063-1314 |
2.39e-09 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 63.54 E-value: 2.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1063 EEPTSPAAAVPTPEEPTsPAAAVPTPEEPTSPAAAVPTPEE-PTSPAAAVPTPE----EPASPAAAVPTPEEPASPAAAV 1137
Cdd:PHA03379 406 EKASEPTYGTPRPPVEK-PRPEVPQSLETATSHGSAQVPEPpPVHDLEPGPLHDqhsmAPCPVAQLPPGPLQDLEPGDQL 484
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1138 PTPEEPAFPAPA-VPTPeesASAAV----AVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAasvPTPAAMVATL 1212
Cdd:PHA03379 485 PGVVQDGRPACApVPAP---AGPIVrpweASLSQVPGVAFAPVMPQPMPVEPVPVPTVALERPVCPA---PPLIAMQGPG 558
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1213 EefTSPAASVPTSEEPASLAaavSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEE 1292
Cdd:PHA03379 559 E--TSGIVRVRERWRPAPWT---PNPPRSPSQMSVRDRLARLRAEAQPYQASVEVQPPQLTQVSPQQPMEYPLEPEQQMF 633
|
250 260
....*....|....*....|..
gi 2245149928 1293 PASPAAAVPTpevaAIPAASVP 1314
Cdd:PHA03379 634 PGSPFSQVAD----VMRAGGVP 651
|
|
| PHA03269 |
PHA03269 |
envelope glycoprotein C; Provisional |
1018-1153 |
2.56e-09 |
|
envelope glycoprotein C; Provisional
Pssm-ID: 165527 [Multi-domain] Cd Length: 566 Bit Score: 63.21 E-value: 2.56e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1018 AAVPTPeeptspaaaVPPPEEPTSPAAAVPTPE-EPTSPAAAVPTP-EEPTSPAAAVPTPEE-PTSPAAAVPTPE-EPTS 1093
Cdd:PHA03269 20 ANLNTN---------IPIPELHTSAATQKPDPApAPHQAASRAPDPaVAPTSAASRKPDLAQaPTPAASEKFDPApAPHQ 90
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1094 PAAAVPTPEE-PTSPAAAVPTPEEPasPAAAVPTPEEPA-SPAAAVPTPEEPAFPAPAVPTP 1153
Cdd:PHA03269 91 AASRAPDPAVaPQLAAAPKPDAAEA--FTSAAQAHEAPAdAGTSAASKKPDPAAHTQHSPPP 150
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
1010-1098 |
2.72e-09 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 63.37 E-value: 2.72e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1010 PEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1089
Cdd:PRK12270 38 PGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDEV 117
|
90
....*....|
gi 2245149928 1090 EP-TSPAAAV 1098
Cdd:PRK12270 118 TPlRGAAAAV 127
|
|
| PTZ00436 |
PTZ00436 |
60S ribosomal protein L19-like protein; Provisional |
1043-1191 |
2.82e-09 |
|
60S ribosomal protein L19-like protein; Provisional
Pssm-ID: 185616 [Multi-domain] Cd Length: 357 Bit Score: 61.89 E-value: 2.82e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1043 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAA 1122
Cdd:PTZ00436 194 AAAAAAKQKAAAKKAAAPSGKKSAKAAAPAKAAAAPAKAAAPPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAAAPPAK 273
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1123 AVPTPEEPASPAAAVPTPEEPAFPAP----AVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVAT 1191
Cdd:PTZ00436 274 AAAPPAKAAAPPAKAAAPPAKAAAAPakaaAAPAKAAAAPAKAAAPPAKAAAPPAKAATPPAKAAAPPAKAAA 346
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
827-1043 |
2.83e-09 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 63.52 E-value: 2.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 827 WI--PVLQrPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAvSAP 904
Cdd:PRK10811 842 WIryPVVR-PQDVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTH-PEV 919
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 905 ERATVPAVTVSVPEGTAAVAAvSSPEETAPAVAAAitqegmsavagfspewaalAITVPITEEDGTPEGPVTPATTVHAP 984
Cdd:PRK10811 920 IAAPVTEQPQVITESDVAVAQ-EVAEHAEPVVEPQ-------------------DETADIEEAAETAEVVVAEPEVVAQP 979
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 985 EEPDTAAVRVSTPEEPASPAAAVPTPeeptsPAAAVPTPEEPTSPAAAVPPPEEPTSPA 1043
Cdd:PRK10811 980 AAPVVAEVAAEVETVTAVEPEVAPAQ-----VPEATVEHNHATAPMTRAPAPEYVPEAP 1033
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
1475-1577 |
3.00e-09 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 56.94 E-value: 3.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1475 KFQDALEPLLSWLADTEELIANQKPPSaEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAElADREKITGQL 1554
Cdd:pfam00435 5 QFFRDADDLESWIEEKEALLSSEDYGK-DLESVQALLKKHKALEAELAAHQDRVEALNELAEKLIDEGH-YASEEIQERL 82
|
90 100
....*....|....*....|...
gi 2245149928 1555 ESLESRWTELLSKAAARQKQLED 1577
Cdd:pfam00435 83 EELNERWEQLLELAAERKQKLEE 105
|
|
| PTZ00436 |
PTZ00436 |
60S ribosomal protein L19-like protein; Provisional |
1056-1207 |
3.05e-09 |
|
60S ribosomal protein L19-like protein; Provisional
Pssm-ID: 185616 [Multi-domain] Cd Length: 357 Bit Score: 61.89 E-value: 3.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1056 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAA 1135
Cdd:PTZ00436 194 AAAAAAKQKAAAKKAAAPSGKKSAKAAAPAKAAAAPAKAAAPPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAAAPPAK 273
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2245149928 1136 AVPTPEEPAFP---APAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATleePTSPAASVPTPAA 1207
Cdd:PTZ00436 274 AAAPPAKAAAPpakAAAPPAKAAAAPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAAT---PPAKAAAPPAKAA 345
|
|
| PHA03291 |
PHA03291 |
envelope glycoprotein I; Provisional |
1031-1156 |
3.22e-09 |
|
envelope glycoprotein I; Provisional
Pssm-ID: 223033 [Multi-domain] Cd Length: 401 Bit Score: 62.28 E-value: 3.22e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAavpTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1110
Cdd:PHA03291 164 AAFPAEGTLAAPPLGEGSADGSCDPAL---PLSAPRLGPADVFVPATPRPTPRTTASPETTPTPSTTTSPPSTTIPAPST 240
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 2245149928 1111 VPTPEEPASpaaavpTPEEPASPAAAVPTPEEpAFPAPAVPTPEES 1156
Cdd:PHA03291 241 TIAAPQAGT------TPEAEGTPAPPTPGGGE-APPANATPAPEAS 279
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
1049-1137 |
3.24e-09 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 63.37 E-value: 3.24e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1049 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPE 1128
Cdd:PRK12270 38 PGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDEV 117
|
90
....*....|
gi 2245149928 1129 EP-ASPAAAV 1137
Cdd:PRK12270 118 TPlRGAAAAV 127
|
|
| PHA03291 |
PHA03291 |
envelope glycoprotein I; Provisional |
968-1077 |
3.91e-09 |
|
envelope glycoprotein I; Provisional
Pssm-ID: 223033 [Multi-domain] Cd Length: 401 Bit Score: 61.89 E-value: 3.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 968 DGTPEGPVTPATTVHAPEEPDtaaVRVSTPE-EPAS---PAAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPPPEEPTSPA 1043
Cdd:PHA03291 169 EGTLAAPPLGEGSADGSCDPA---LPLSAPRlGPADvfvPATPRPTPRTTASPETT-PTPSTTTSPPSTTIPAPSTTIAA 244
|
90 100 110
....*....|....*....|....*....|....*
gi 2245149928 1044 -AAVPTPEEPTSPAAAVPTPEEpTSPAAAVPTPEE 1077
Cdd:PHA03291 245 pQAGTTPEAEGTPAPPTPGGGE-APPANATPAPEA 278
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
3014-3138 |
4.22e-09 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 56.57 E-value: 4.22e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 3014 LEELLAWIQWAETTLiqrDQEPIPQNIDRVKALIAEHQTFMEEMTRKQPDVDRVTKTYKR-KNIEPTHAPFIEKsrsggr 3092
Cdd:smart00150 7 ADELEAWLEEKEQLL---ASEDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQlIEEGHPDAEEIEE------ 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 2245149928 3093 kslsqptpppmpilsqseaknpRINQLSARWQQVWLLALERQRKLN 3138
Cdd:smart00150 78 ----------------------RLEELNERWEELKELAEERRQKLE 101
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
833-1172 |
5.02e-09 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 62.50 E-value: 5.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 833 RPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFP-----------------------HEDILVASIV 889
Cdd:PHA03307 613 GAAAPAPAAPRPDAAAAGGASARPLRELADACVLACRAVLEALLEGPdglsavpglafprpacppraleaCPARLESWLR 692
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 890 SLEEedvTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEET-APAVAAAItqEGMSAVAgfspewAALAITVPITEED 968
Cdd:PHA03307 693 ELRD---LRDAVYLARLRGDLPVAGGREERVAAVRAVSLVARTvAPLVRYSP--RRARARA------SAWDITDALFSNP 761
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 969 GTPEGPVTPATTVHAPEEPDTAA-VRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPE---EPTSPAAAVPPPEEPTSPAA 1044
Cdd:PHA03307 762 SLVPAKLAEALALLEPAEPQRGAgSSPPVRAEAAFRRPGRLRRSGPAADAASRTASKrksRSHTPDGGSESSGPARPPGA 841
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1045 AVPtpeeptSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASP---- 1120
Cdd:PHA03307 842 AAR------PPPARSSESSKSKPAAAGGRARGKNGRRRPRPPEPRARPGAAAPPKAAAAAPPAGAPAPRPRPAPRVklgp 915
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1121 ------------------AAAVPTPEEPA-----SPAAAVPTPEEPAFPAPAVPT----PEESAS-AAVAVPTPEESASP 1172
Cdd:PHA03307 916 mppggpdprggfrrvppgDLHTPAPSAAAlaaycPPEVVAELVDHPLFPEPWRPAlafdPEALAEiAARCGGPPPRSGSA 995
|
|
| DamX |
COG3266 |
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ... |
891-1175 |
6.19e-09 |
|
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442497 [Multi-domain] Cd Length: 455 Bit Score: 61.40 E-value: 6.19e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 891 LEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFS--PEWAALAITVPITEED 968
Cdd:COG3266 82 ALASLALLGILLLALLALLLDLLLLADLLRAAALLLLKLLLLLLTLLLLVLLLLLALLLALLldLPLLTLLIVLPLLEEQ 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 969 GTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPT 1048
Cdd:COG3266 162 LLLLALQDIQGTLQALGAVAALLGLRKAEEALALRAGSAAADALALLLLLLASALGEAVAAAAELAALALLAAGAAEVLT 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1049 PEEPTSPAAAVPTPEEPTSPAAAvPTPEeptsPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPAsPAAAVPTPE 1128
Cdd:COG3266 242 ARLVLLLLIIGSALKAPSQASSA-SAPA----TTSLGEQQEVSLPPAVAAQPAAAAAAQPSAVALPAAPA-AAAAAAAPA 315
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 2245149928 1129 EPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAA 1175
Cdd:COG3266 316 EAAAPQPTAAKPVVTETAAPAAPAPEAAAAAAAPAAPAVAKKLAADE 362
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1647-2380 |
6.93e-09 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 62.29 E-value: 6.93e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1647 LLKQTTGEEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQ--STYEELTGWLREVEEELATsggqsptgeQ 1724
Cdd:TIGR00618 205 LLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEeqLKKQQLLKQLRARIEELRA---------Q 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1725 IPQFQQRQKELKKEVMEHRLVLDTvnevsrALLELVPWRAREGLDKLVSDANEQYKLVSDTIGQRVDEIDAAIQRS---- 1800
Cdd:TIGR00618 276 EAVLEETQERINRARKAAPLAAHI------KAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRllqt 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1801 -----QQYEQAADAELAWVAETKRKLMALGPIR-LEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRSEifgtCGEEQK 1874
Cdd:TIGR00618 350 lhsqeIHIRDAHEVATSIREISCQQHTLTQHIHtLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAF----RDLQGQ 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1875 TVLQEKTESLIQQYEAISLLNSERYARLERAQ-VLVNQFWETYEELSPWIEETRALIAQLPSPAIDHEQ-LRQQQEEMRQ 1952
Cdd:TIGR00618 426 LAHAKKQQELQQRYAELCAAAITCTAQCEKLEkIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLArLLELQEEPCP 505
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1953 LRESIAEHKPHIDKLLKIGPQLKELnpEEGEMVEEKYQKA-ENMYAQIKEEVRQRALALDEAVS--QSTQI-TEFHDKIE 2028
Cdd:TIGR00618 506 LCGSCIHPNPARQDIDNPGPLTRRM--QRGEQTYAQLETSeEDVYHQLTSERKQRASLKEQMQEiqQSFSIlTQCDNRSK 583
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2029 PMLETLENLSSRLRmpPLIPAEVdkiRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQm 2108
Cdd:TIGR00618 584 EDIPNLQNITVRLQ--DLTEKLS---EAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQ- 657
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2109 vffwedikaraEEREIKFLDVLELAEKFWYDMAALLTtikdtqdivhdlespgidpsiikqqveAAETIKEETDGLHEEL 2188
Cdd:TIGR00618 658 -----------ERVREHALSIRVLPKELLASRQLALQ---------------------------KMQSEKEQLTYWKEML 699
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2189 EFIrilgaDLIFACGETEKPEVRKSIDEmnnaWENLNKTWKERLEKLEDAMQaavQYQDTLQAMFDWL--DNTVIKLCTM 2266
Cdd:TIGR00618 700 AQC-----QTLLRELETHIEEYDREFNE----IENASSSLGSDLAAREDALN---QSLKELMHQARTVlkARTEAHFNNN 767
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2267 PPVGTDLNTvkdqLNEMKEFKVEVYQQQIEMEKLnhQGELMLKKATDETDRDiirEPLTELKHLWENLGEKIAHRQHKLE 2346
Cdd:TIGR00618 768 EEVTAALQT----GAELSHLAAEIQFFNRLREED--THLLKTLEAEIGQEIP---SDEDILNLQCETLVQEEEQFLSRLE 838
|
730 740 750
....*....|....*....|....*....|....
gi 2245149928 2347 GALLALGQFQHALEELMSWLTHTEELLDAQRPIS 2380
Cdd:TIGR00618 839 EKSATLGEITHQLLKYEECSKQLAQLTQEQAKII 872
|
|
| PTZ00436 |
PTZ00436 |
60S ribosomal protein L19-like protein; Provisional |
988-1162 |
6.96e-09 |
|
60S ribosomal protein L19-like protein; Provisional
Pssm-ID: 185616 [Multi-domain] Cd Length: 357 Bit Score: 60.73 E-value: 6.96e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 988 DTAAVRVSTPEEPASPAAAVPTPEEptSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPeeptS 1067
Cdd:PTZ00436 191 EDAAAAAAAKQKAAAKKAAAPSGKK--SAKAAAPAKAAAAPAKAAAPPAKAAAAPAKAAAAPAKAAAPPAKAAAP----P 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1068 PAAAVPTPEEPTSPAAAVPTPeeptSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPeepafPA 1147
Cdd:PTZ00436 265 AKAAAPPAKAAAPPAKAAAPP----AKAAAPPAKAAAAPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAATP-----PA 335
|
170
....*....|....*
gi 2245149928 1148 PAVPTPEESASAAVA 1162
Cdd:PTZ00436 336 KAAAPPAKAAAAPVG 350
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
985-1192 |
7.05e-09 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 62.03 E-value: 7.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 985 EEPDTAAVRVSTPEEPASPAAAVPTPEEPTS------PAAAVPTPEEPTSPAAA------VPPPEEPTSPAAAvPTPEEP 1052
Cdd:PRK08691 373 ENTELQSPSAQTAEKETAAKKPQPRPEAETAqtpvqtASAAAMPSEGKTAGPVSnqenndVPPWEDAPDEAQT-AAGTAQ 451
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1053 TsPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT-SPAAAVPTPEEPTSPAAAVPTPEEPaSPAAAVPTPEEPA 1131
Cdd:PRK08691 452 T-SAKSIQTASEAETPPENQVSKNKAADNETDAPLSEVPSeNPIQATPNDEAVETETFAHEAPAEP-FYGYGFPDNDCPP 529
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1132 SPAAAVPTPE-EPAFPAPAVPTPEESASAAVAVPTPEESASPaaavPTPAESASFAAVVATL 1192
Cdd:PRK08691 530 EDGAEIPPPDwEHAAPADTAGGGADEEAEAGGIGGNNTPSAP----PPEFSTENWAAIVRHF 587
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
1036-1124 |
7.16e-09 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 62.22 E-value: 7.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1036 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1115
Cdd:PRK12270 38 PGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDEV 117
|
90
....*....|
gi 2245149928 1116 EP-ASPAAAV 1124
Cdd:PRK12270 118 TPlRGAAAAV 127
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
2682-2785 |
7.77e-09 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 55.79 E-value: 7.77e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2682 QFHEAWKKLIDWLEDAESHLDSElEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKtlLPEDSQKLDNF 2761
Cdd:pfam00435 5 QFFRDADDLESWIEEKEALLSSE-DYGKDLESVQALLKKHKALEAELAAHQDRVEALNELAEKLIDE--GHYASEEIQER 81
|
90 100
....*....|....*....|....
gi 2245149928 2762 LGEVRDKWDTVCGKSVERQHKLEE 2785
Cdd:pfam00435 82 LEELNERWEQLLELAAERKQKLEE 105
|
|
| FAP |
pfam07174 |
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment ... |
1030-1120 |
8.32e-09 |
|
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment proteins (FAP). Family members are rich in alanine and proline, are approximately 300 long, and seem to be restricted to mycobacteria. These proteins contain a fibronectin-binding motif that allows mycobacteria to bind to fibronectin in the extracellular matrix.
Pssm-ID: 429334 Cd Length: 301 Bit Score: 59.94 E-value: 8.32e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1030 AAAVPPPEepTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPeePTSPAAAVPTPEEPTSPAa 1109
Cdd:pfam07174 28 AVAVALPA--VAHADPEPAPPPPSTATAPPAPPPPPPAPAAPAPPPPPAAPNAPNAPPP--PADPNAPPPPPADPNAPP- 102
|
90
....*....|.
gi 2245149928 1110 avPTPEEPASP 1120
Cdd:pfam07174 103 --PPAVDPNAP 111
|
|
| DUF4045 |
pfam13254 |
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. ... |
997-1145 |
9.36e-09 |
|
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. This domain family is found in bacteria and eukaryotes, and is typically between 384 and 430 amino acids in length.
Pssm-ID: 433066 [Multi-domain] Cd Length: 415 Bit Score: 60.57 E-value: 9.36e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 997 PEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1076
Cdd:pfam13254 208 LMRSPAPGGHSKSPSVSGISADSSPTKEEPSEEADTLSTDKEQSPAPTSASEPPPKTKELPKDSEEPAAPSKSAEASTEK 287
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 1077 EPTSPAAAVPTPEEPTSPAAAVPTPeEPTSPAAAVPTPEEPASPaaaVPTPEEPAS----------PAAAVPTPEEPAF 1145
Cdd:pfam13254 288 KEPDTESSPETSSEKSAPSLLSPVS-KASIDKPLSSPDRDPLSP---KPKPQSPPKdfranlrsreVPKDKSKKDEPEF 362
|
|
| DamX |
COG3266 |
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ... |
787-1126 |
1.05e-08 |
|
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442497 [Multi-domain] Cd Length: 455 Bit Score: 60.63 E-value: 1.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 787 LNVASSEGGEMERRDSDSFLNIFPEKQVTKAGNTEPVLEEwIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAP 866
Cdd:COG3266 49 LRLLLLAGLLLLLIRLLSEAVDLGALASAALLLALASLAL-LGILLLALLALLLDLLLLADLLRAAALLLLKLLLLLLTL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 867 EGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMS 946
Cdd:COG3266 128 LLLVLLLLLALLLALLLDLPLLTLLIVLPLLEEQLLLLALQDIQGTLQALGAVAALLGLRKAEEALALRAGSAAADALAL 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 947 AVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPeeptspaaAVPTPEEP 1026
Cdd:COG3266 208 LLLLLASALGEAVAAAAELAALALLAAGAAEVLTARLVLLLLIIGSALKAPSQASSASAPATTS--------LGEQQEVS 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1027 TSPAAAVPPPEEPTSPAAAVPTPEEPtSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAavptpeePTS 1106
Cdd:COG3266 280 LPPAVAAQPAAAAAAQPSAVALPAAP-AAAAAAAAPAEAAAPQPTAAKPVVTETAAPAAPAPEAAAAAAA-------PAA 351
|
330 340
....*....|....*....|
gi 2245149928 1107 PAAAVPTPEEPASPAAAVPT 1126
Cdd:COG3266 352 PAVAKKLAADEQWLASQPAS 371
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
1008-1184 |
1.15e-08 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 60.99 E-value: 1.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1008 PTPEEPTSPAAAVPTPEEPTSPA------AAVPPPEEPTSPAAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPTPEE--PT 1079
Cdd:PRK14086 90 PSAGEPAPPPPHARRTSEPELPRpgrrpyEGYGGPRADDRPPGLPRQDQLPTARPAY-PAYQQRPEPGAWPRAADDygWQ 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1080 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEepafPAPAVPTPEESASA 1159
Cdd:PRK14086 169 QQRLGFPPRAPYASPASYAPEQERDREPYDAGRPEYDQRRRDYDHPRPDWDRPRRDRTDRPE----PPPGAGHVHRGGPG 244
|
170 180
....*....|....*....|....*.
gi 2245149928 1160 AVAVPT-PEESASPAAAVPTPAESAS 1184
Cdd:PRK14086 245 PPERDDaPVVPIRPSAPGPLAAQPAP 270
|
|
| FAP |
pfam07174 |
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment ... |
989-1081 |
1.19e-08 |
|
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment proteins (FAP). Family members are rich in alanine and proline, are approximately 300 long, and seem to be restricted to mycobacteria. These proteins contain a fibronectin-binding motif that allows mycobacteria to bind to fibronectin in the extracellular matrix.
Pssm-ID: 429334 Cd Length: 301 Bit Score: 59.55 E-value: 1.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 989 TAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPeePTSPAAAVPTPEEPTSP 1068
Cdd:pfam07174 24 AGASAVAVALPAVAHADPEPAPPPPSTATAPPAPPPPPPAPAAPAPPPPPAAPNAPNAPPP--PADPNAPPPPPADPNAP 101
|
90
....*....|...
gi 2245149928 1069 AaavPTPEEPTSP 1081
Cdd:pfam07174 102 P---PPAVDPNAP 111
|
|
| PRK13108 |
PRK13108 |
prolipoprotein diacylglyceryl transferase; Reviewed |
1011-1187 |
1.22e-08 |
|
prolipoprotein diacylglyceryl transferase; Reviewed
Pssm-ID: 237284 [Multi-domain] Cd Length: 460 Bit Score: 60.76 E-value: 1.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1011 EEPTSPAAAVPTPEEPTSPaaavpppeEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP-TPEEPTSPAAAVPTPE 1089
Cdd:PRK13108 280 EAPGALRGSEYVVDEALER--------EPAELAAAAVASAASAVGPVGPGEPNQPDDVAEAVKaEVAEVTDEVAAESVVQ 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1090 EPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAavptPEEPAFPAPAVPTPEESASAAVAVPT---- 1165
Cdd:PRK13108 352 VADRDGESTPAVEETSEADIEREQPGDLAGQAPAAHQVDAEAASAA----PEEPAALASEAHDETEPEVPEKAAPIpdpa 427
|
170 180
....*....|....*....|...
gi 2245149928 1166 -PEESASpAAAVPTPAESASFAA 1187
Cdd:PRK13108 428 kPDELAV-AGPGDDPAEPDGIRR 449
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
2569-2675 |
1.24e-08 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 55.02 E-value: 1.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2569 NLATEFQNSLQEFINWLTLAEQSLNIASPPSLiLNTVLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFlSQKQDVVLI 2648
Cdd:pfam00435 1 LLLQQFFRDADDLESWIEEKEALLSSEDYGKD-LESVQALLKKHKALEAELAAHQDRVEALNELAEKLID-EGHYASEEI 78
|
90 100
....*....|....*....|....*..
gi 2245149928 2649 KNLLVSVQSRWEKVVQRSIERGRSLDD 2675
Cdd:pfam00435 79 QERLEELNERWEQLLELAAERKQKLEE 105
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
1041-1308 |
1.61e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 60.88 E-value: 1.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1041 SPAAAvptpeePTSPAAAVPTPEEPTSPAAAvpTPEEPTSPAAAVPTPEeptspaaavptpeeptspAAAVPTPEEPASp 1120
Cdd:PRK08691 359 APLAA------ASCDANAVIENTELQSPSAQ--TAEKETAAKKPQPRPE------------------AETAQTPVQTAS- 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1121 AAAVPTPEEPASPAaavpTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESaSFAAVVATLEEPTSPAA 1200
Cdd:PRK08691 412 AAAMPSEGKTAGPV----SNQENNDVPPWEDAPDEAQTAAGTAQTSAKSIQTASEAETPPEN-QVSKNKAADNETDAPLS 486
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1201 SVPTPAamvatleeftsPAASVPTSEEPASLAAAVSNPEEPtSPAAAVPTLEEPTSSAAAVLTPE-ELSSPAASVPTPEE 1279
Cdd:PRK08691 487 EVPSEN-----------PIQATPNDEAVETETFAHEAPAEP-FYGYGFPDNDCPPEDGAEIPPPDwEHAAPADTAGGGAD 554
|
250 260
....*....|....*....|....*....
gi 2245149928 1280 PASPAAAVSNLEEPASPAAAVPTPEVAAI 1308
Cdd:PRK08691 555 EEAEAGGIGGNNTPSAPPPEFSTENWAAI 583
|
|
| DamX |
COG3266 |
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ... |
847-1141 |
1.69e-08 |
|
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442497 [Multi-domain] Cd Length: 455 Bit Score: 60.25 E-value: 1.69e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 847 LDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPE--------RATVPAVTVSVPE 918
Cdd:COG3266 71 LGALASAALLLALASLALLGILLLALLALLLDLLLLADLLRAAALLLLKLLLLLLTLLLlvlllllaLLLALLLDLPLLT 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 919 GTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPE 998
Cdd:COG3266 151 LLIVLPLLEEQLLLLALQDIQGTLQALGAVAALLGLRKAEEALALRAGSAAADALALLLLLLASALGEAVAAAAELAALA 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 999 EPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPpeeptSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1078
Cdd:COG3266 231 LLAAGAAEVLTARLVLLLLIIGSALKAPSQASSASAP-----ATTSLGEQQEVSLPPAVAAQPAAAAAAQPSAVALPAAP 305
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1079 tSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAavptpeePASPAAAVPTPE 1141
Cdd:COG3266 306 -AAAAAAAAPAEAAAPQPTAAKPVVTETAAPAAPAPEAAAAAAA-------PAAPAVAKKLAA 360
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
1108-1315 |
1.75e-08 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 60.50 E-value: 1.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1108 AAAVPTpeepASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVP-------TPEESASAAVAV-------PTPEESASPA 1173
Cdd:PRK14951 300 LQAVPQ----AAAAATDPEAAEVARLAALMPADETQLLYSICLHgraelglAPDEYAALTMVLlrllafkPAAAAEAAAP 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1174 AAVPTPAESAsfAAVVATLEEPTSPAASVPTPAAMVAtleefTSPAASVPTSEEPAslAAAVSNPEEPTSPAAAVPTLEE 1253
Cdd:PRK14951 376 AEKKTPARPE--AAAPAAAPVAQAAAAPAPAAAPAAA-----ASAPAAPPAAAPPA--PVAAPAAAAPAAAPAAAPAAVA 446
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1254 PTSSAAAVLTPEELSSPAASVPTPEEPASPAAAvsnleEPASPAAAVPTPEVAAIPAASVPT 1315
Cdd:PRK14951 447 LAPAPPAQAAPETVAIPVRVAPEPAVASAAPAP-----AAAPAAARLTPTEEGDVWHATVQQ 503
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
829-1314 |
1.94e-08 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 60.46 E-value: 1.94e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 829 PVLQRPsRTAAVPTVKDALDA-ALPSPEEGTSIAAVPAPegTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERA 907
Cdd:PHA03379 418 PPVEKP-RPEVPQSLETATSHgSAQVPEPPPVHDLEPGP--LHDQHSMAPCPVAQLPPGPLQDLEPGDQLPGVVQDGRPA 494
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 908 TVPAvtvsvpegtaavaavsspeetaPAVAAAITQEgmsavagfspeWAALAITVPiteedGTPEGPVTPAttvHAPEEP 987
Cdd:PHA03379 495 CAPV----------------------PAPAGPIVRP-----------WEASLSQVP-----GVAFAPVMPQ---PMPVEP 533
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 988 D-TAAVRVSTPEEPASPAAAVPTPEEPTS---------PAAAVPTPEEPTSPA------AAVPPPEEPTSPAAAVPTPEE 1051
Cdd:PHA03379 534 VpVPTVALERPVCPAPPLIAMQGPGETSGivrvrerwrPAPWTPNPPRSPSQMsvrdrlARLRAEAQPYQASVEVQPPQL 613
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1052 PTSPaaavptPEEPTSPAAAVPTPEEPTSPAAAVP-TPEEPTSPAAavptpeEPTSPAAAVPTPEEPASPAAAVPTPEEP 1130
Cdd:PHA03379 614 TQVS------PQQPMEYPLEPEQQMFPGSPFSQVAdVMRAGGVPAM------QPQYFDLPLQQPISQGAPLAPLRASMGP 681
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1131 ASPaaaVPTPEEPAFPAPAVPTPEESASAAVAVP--------TPEESASPAAAV-----PTPAESASFAAVVATLEEPTS 1197
Cdd:PHA03379 682 VPP---VPATQPQYFDIPLTEPINQGASAAHFLPqqpmegplVPERWMFQGATLsqsvrPGVAQSQYFDLPLTQPINHGA 758
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1198 PAASV----PTPAAMVATLEEFTSPAASVPTSEEPASLAA------AVSNPEEPTSPA--------AAVPTLEEPTSSAA 1259
Cdd:PHA03379 759 PAAHFlhqpPMEGPWVPEQWMFQGAPPSQGTDVVQHQLDAlgyvlhVLNHPGVPVSPAvnqyhvsqAAFGLPIDEDESGE 838
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 1260 AVLTPEELSSPAASV---PTPEEPASPAAavsnlEEPASPAAAVPTPEVAAIPAASVP 1314
Cdd:PHA03379 839 GSDTSEPCEALDLSIhgrPCPQAPEWPVQ-----GEGGQDATEVLDLSIHGRPRPRTP 891
|
|
| FAP |
pfam07174 |
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment ... |
955-1068 |
1.98e-08 |
|
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment proteins (FAP). Family members are rich in alanine and proline, are approximately 300 long, and seem to be restricted to mycobacteria. These proteins contain a fibronectin-binding motif that allows mycobacteria to bind to fibronectin in the extracellular matrix.
Pssm-ID: 429334 Cd Length: 301 Bit Score: 58.78 E-value: 1.98e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 955 WAALAITVpiteedgtpegpVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1034
Cdd:pfam07174 15 WATLAIAA------------VAGASAVAVALPAVAHADPEPAPPPPSTATAPPAPPPPPPAPAAPAPPPPPAAPNAPNAP 82
|
90 100 110
....*....|....*....|....*....|....
gi 2245149928 1035 PPeePTSPAAAVPTPEEPTSPAaavPTPEEPTSP 1068
Cdd:pfam07174 83 PP--PADPNAPPPPPADPNAPP---PPAVDPNAP 111
|
|
| KREPA2 |
cd23959 |
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of ... |
1027-1243 |
2.06e-08 |
|
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of the parasitic protozoan's KREPA RNA editing catalytic complex (RECC). Kinetoplastid RNA editing (KRE) proteins occur as pairs or sets of related proteins in multiple complexes. KREPA complex is composed of six components (KREPA1-6), which share a conserved C-terminal region containing an oligonucleotide-binding (OB)-fold-like domain. KREPAs are responsible for the site-specific insertion and deletion of U nucleotides in the kinetoplastid mitochondria pre-messenger RNA. Apart from the conserved C-terminal OB-fold domain, KREPA1, KREPA2, and KREPA3 contain two conserved C2H2 zinc-finger domains. KREPA2 and kinetoplastid RNA editing ligase 1 (KREL1) are specific for ligation post-U-deletion and are paralogous to KREL2 and KREPA1 that are specific for ligation post-U-insertion. KREPA2, is critical for RECC stability and KREL1 integration into the complex.
Pssm-ID: 467780 [Multi-domain] Cd Length: 424 Bit Score: 59.88 E-value: 2.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1027 TSPAAAVPPPEEPTSPAAAvPTPEEPTSPAAAVPTPEEPTSPAAAvptpeEPTSPAAAVPTPEEPTSP--AAAVPTP-EE 1103
Cdd:cd23959 48 ARPSDQEEPLYGAVSPEGE-NPFDGPGLVTASTVSDCYVGNANFY-----EVDMSDAFAMAPDESLGPfrAARVPNPfSA 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1104 PTSPAAAVPTPEEPASPAAAVPTPeePASPAAAVPTPEEPafPAPAVPTPEESASAAVAVPtPEESASPAAAVPTPAesA 1183
Cdd:cd23959 122 SSSTQRETHKTAQVAPPKAEPQTA--PVTPFGQLPMFGQH--PPPAKPLPAAAAAQQSSAS-PGEVASPFASGTVSA--S 194
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1184 SFAAVVATLEEPTSPAASVPTPAAmvatleefTSPAASVPTSEepASLAAAVSNPEEPTS 1243
Cdd:cd23959 195 PFATATDTAPSSGAPDGFPAEASA--------PSPFAAPASAA--SFPAAPVANGEAATP 244
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
1050-1138 |
2.25e-08 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 60.67 E-value: 2.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1050 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPeepTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEE 1129
Cdd:PRK12270 34 ADYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAP---APPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAA 110
|
....*....
gi 2245149928 1130 PASPAAAVP 1138
Cdd:PRK12270 111 AAVEDEVTP 119
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1879-2515 |
2.69e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 60.08 E-value: 2.69e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1879 EKTESLIQQYEAISLLNSERYARLEraqvlvnqfwETYEELSPWIEETRALIAQLpspaidhEQLRQQQEEMRQLRESIA 1958
Cdd:PRK03918 179 ERLEKFIKRTENIEELIKEKEKELE----------EVLREINEISSELPELREEL-------EKLEKEVKELEELKEEIE 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1959 EHKPHIDKLLKIGPQLKELNPEEGEMVEEKYQKAENMyaqikEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLS 2038
Cdd:PRK03918 242 ELEKELESLEGSKRKLEEKIRELEERIEELKKEIEEL-----EEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRL 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2039 SRLRmpplipAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQgadkdlAAKEIQDKLDQMvffwEDIKAR 2118
Cdd:PRK03918 317 SRLE------EEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHE------LYEEAKAKKEEL----ERLKKR 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2119 AEEREI-KFLDVLELAEKfwydmaallttikdtqdivhdlespgidpsiikqqveAAETIKEETDGLHEELEFIRILGAD 2197
Cdd:PRK03918 381 LTGLTPeKLEKELEELEK-------------------------------------AKEEIEEEISKITARIGELKKEIKE 423
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2198 LIFACGETEK-----PEVRKSIDEMNNawENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTD 2272
Cdd:PRK03918 424 LKKAIEELKKakgkcPVCGRELTEEHR--KELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKEL 501
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2273 LNTVKDQLNEMKEFKVE-VYQQQIEMEKLNHQ-----GELMLKKATDETDRDIIREpLTELKHLWENLGEKIAhrqhKLE 2346
Cdd:PRK03918 502 AEQLKELEEKLKKYNLEeLEKKAEEYEKLKEKliklkGEIKSLKKELEKLEELKKK-LAELEKKLDELEEELA----ELL 576
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2347 GALLALGqFQhALEELMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKndvlahqatvETVNKAGNELLESSAgdDA 2426
Cdd:PRK03918 577 KELEELG-FE-SVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLE----------EELDKAFEELAETEK--RL 642
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2427 SSLRSRLEAMNQCWesvlqkTEEReqqlqstlqqaqgfHSEIEDFLLELTRMESQLSASKptgglpETAREQLDTHMELY 2506
Cdd:PRK03918 643 EELRKELEELEKKY------SEEE--------------YEELREEYLELSRELAGLRAEL------EELEKRREEIKKTL 696
|
....*....
gi 2245149928 2507 SQLKAKEET 2515
Cdd:PRK03918 697 EKLKEELEE 705
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
1060-1206 |
3.20e-08 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 58.63 E-value: 3.20e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1060 PTPEEPTSPAAAVPTPEeptsPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPT 1139
Cdd:NF040712 190 PDFGRPLRPLATVPRLA----REPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAA 265
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1140 PEEPAFPAPAVPTPEEsasaAVAVPTPEESASPAAAVPTPAESASFAAVvatlEEPTSPAASVPTPA 1206
Cdd:NF040712 266 PAAEPDEATRDAGEPP----APGAAETPEAAEPPAPAPAAPAAPAAPEA----EEPARPEPPPAPKP 324
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
974-1090 |
3.43e-08 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 59.44 E-value: 3.43e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 974 PVTPATTVhAPEEPDTAAVRvSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPaaavptpeePT 1053
Cdd:PRK14950 362 PVPAPQPA-KPTAAAPSPVR-PTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESA---------PK 430
|
90 100 110
....*....|....*....|....*....|....*..
gi 2245149928 1054 SPAAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPTPEE 1090
Cdd:PRK14950 431 LTRAAIPVDEKPKYTPPA-PPKEEEKALIADGDVLEQ 466
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
922-1148 |
3.63e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 59.72 E-value: 3.63e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 922 AVAAVSSPEETAPAVAAAITQEGMSAVAgfsPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPA 1001
Cdd:PRK08691 357 AFAPLAAASCDANAVIENTELQSPSAQT---AEKETAAKKPQPRPEAETAQTPVQTASAAAMPSEGKTAGPVSNQENNDV 433
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1002 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAvptPEEPTSPAAAVPTPeeptSPAAAVPTPEEPTSP 1081
Cdd:PRK08691 434 PPWEDAPDEAQTAAGTAQTSAKSIQTASEAETPPENQVSKNKAA---DNETDAPLSEVPSE----NPIQATPNDEAVETE 506
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 1082 AAAVPTPEEPtSPAAAVPTPEEPTSPAAAVPTPE-EPASPAAAVPTPEEPASPAAAVPTPEEPAFPAP 1148
Cdd:PRK08691 507 TFAHEAPAEP-FYGYGFPDNDCPPEDGAEIPPPDwEHAAPADTAGGGADEEAEAGGIGGNNTPSAPPP 573
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
907-1083 |
3.66e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 59.49 E-value: 3.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 907 ATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAgfspewaalaiTVPITEEDGTPEGPVTPATTVHAPEE 986
Cdd:PRK07994 362 AAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPA-----------SAPQQAPAVPLPETTSQLLAARQQLQ 430
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 987 pdtaAVRVSTPEEPASPAAAVPTPeeptsPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT 1066
Cdd:PRK07994 431 ----RAQGATKAKKSEPAAASRAR-----PVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALK 501
|
170
....*....|....*..
gi 2245149928 1067 SPAAAVPTPEEPTSPAA 1083
Cdd:PRK07994 502 KALEHEKTPELAAKLAA 518
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1730-2521 |
3.80e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 59.69 E-value: 3.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1730 QRQKELKKEVMEHRLVLdtvnevsrALLELVpwRAREGLDKLVSDANEQyklvsdtiGQRVDEIDAAIQrsqqyeqAADA 1809
Cdd:TIGR02168 213 ERYKELKAELRELELAL--------LVLRLE--ELREELEELQEELKEA--------EEELEELTAELQ-------ELEE 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1810 ELawvaETKRKLMAlgpiRLEQDQTTAQlqvqkafsidiirhkdsmDELFSHRSEIFGTcgEEQKTVLQEKTESLIQQYE 1889
Cdd:TIGR02168 268 KL----EELRLEVS----ELEEEIEELQ------------------KELYALANEISRL--EQQKQILRERLANLERQLE 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1890 AISLLNSERYARLERAQVLVNQFWETYEELSPWIEETRALIAQLPSPAID-HEQLRQQQEEMRQLRESIAEHKphidkll 1968
Cdd:TIGR02168 320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEElESRLEELEEQLETLRSKVAQLE------- 392
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1969 kigPQLKELNPEEGEMVEEKYQKAENMyAQIKEEVRQRALALDEAVSQSTQiTEFHDKIEPMLETLENLSSRLRMPPLIP 2048
Cdd:TIGR02168 393 ---LQIASLNNEIERLEARLERLEDRR-ERLQQEIEELLKKLEEAELKELQ-AELEELEEELEELQEELERLEEALEELR 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2049 AEVDKIRECISDNKSatvELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVffWEDIKARAE-EREI--- 2124
Cdd:TIGR02168 468 EELEEAEQALDAAER---ELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVL--SELISVDEGyEAAIeaa 542
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2125 --KFLD--VLELAEKFWYDMAAL------------LTTIKDTQDIVHDLESP-------GIDPSIIKQQVEA-------- 2173
Cdd:TIGR02168 543 lgGRLQavVVENLNAAKKAIAFLkqnelgrvtflpLDSIKGTEIQGNDREILkniegflGVAKDLVKFDPKLrkalsyll 622
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2174 -----AETIKEETDGLHEELEFIRI--LGADLIFACG----ETEKP-----EVRKSIDEmnnAWENLNKTwKERLEKLED 2237
Cdd:TIGR02168 623 ggvlvVDDLDNALELAKKLRPGYRIvtLDGDLVRPGGvitgGSAKTnssilERRREIEE---LEEKIEEL-EEKIAELEK 698
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2238 AMQAAVQYQDTLQAMFDWLDNTVIKLctmppvGTDLNTVKDQLnEMKEFKVEVYQQQIEMEKLNhQGELMLKKATDETDR 2317
Cdd:TIGR02168 699 ALAELRKELEELEEELEQLRKELEEL------SRQISALRKDL-ARLEAEVEQLEERIAQLSKE-LTELEAEIEELEERL 770
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2318 DIIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEEL-MSWLTHTEELLDAQRPISGDPKVIEVELAKHHVL 2396
Cdd:TIGR02168 771 EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLnEEAANLRERLESLERRIAATERRLEDLEEQIEEL 850
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2397 KNDVLAHQATVETVNKAGNELLE---------SSAGDDASSLRSRLEAMnqcwESVLQKTEEREQQLQSTLQQAQgfhSE 2467
Cdd:TIGR02168 851 SEDIESLAAEIEELEELIEELESeleallnerASLEEALALLRSELEEL----SEELRELESKRSELRRELEELR---EK 923
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 2468 IEDFLLELTRMESQLSaskptgGLPETAREQLDTHMELYSQLKAKEETYNQLLD 2521
Cdd:TIGR02168 924 LAQLELRLEGLEVRID------NLQERLSEEYSLTLEEAEALENKIEDDEEEAR 971
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
891-1106 |
3.92e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 59.34 E-value: 3.92e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 891 LEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAitvpitEEDGT 970
Cdd:PRK08691 372 IENTELQSPSAQTAEKETAAKKPQPRPEAETAQTPVQTASAAAMPSEGKTAGPVSNQENNDVPPWEDAP------DEAQT 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 971 PEGPV-TPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPT-SPAAAVPTPEEPTSPAAAVPPPEEPtSPAAAVPT 1048
Cdd:PRK08691 446 AAGTAqTSAKSIQTASEAETPPENQVSKNKAADNETDAPLSEVPSeNPIQATPNDEAVETETFAHEAPAEP-FYGYGFPD 524
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2245149928 1049 PEEPTSPAAAVPtpeeptspaaavPTPEEPTSPAAAVPTPEEPTSPAAAV---PTPEEPTS 1106
Cdd:PRK08691 525 NDCPPEDGAEIP------------PPDWEHAAPADTAGGGADEEAEAGGIggnNTPSAPPP 573
|
|
| PRK10905 |
PRK10905 |
cell division protein DamX; Validated |
979-1101 |
4.38e-08 |
|
cell division protein DamX; Validated
Pssm-ID: 236792 [Multi-domain] Cd Length: 328 Bit Score: 58.03 E-value: 4.38e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 979 TTVHAPEEPDTAAVRVSTPEEPASPA------AAVPTPEEPTSPAAAVPTPE------EPTSPAAAVPPPEEPTspaAAV 1046
Cdd:PRK10905 106 TQPQNQQQLNNVAVNSTLPTEPATVApvrngnASRQTAKTQTAERPATTRPArkqaviEPKKPQATAKTEPKPV---AQT 182
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 2245149928 1047 PTPEEPTSPAAAVPTPEEPTSPAAavptpeEPTSPAAAVPTPeeptSPAAAVPTP 1101
Cdd:PRK10905 183 PKRTEPAAPVASTKAPAATSTPAP------KETATTAPVQTA----SPAQTTATP 227
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
1181-1317 |
4.43e-08 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 58.96 E-value: 4.43e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1181 ESASFAAVVATLEEPTSPAASVPTPAAMVATleeftsPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAA 1260
Cdd:PRK14951 367 AAAAEAAAPAEKKTPARPEAAAPAAAPVAQA------AAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAA 440
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1261 VLTPEELSSPAASVPTPEEPASPAAAVSnleEPASPAAAvPTPEVAAIPAASVPTPE 1317
Cdd:PRK14951 441 APAAVALAPAPPAQAAPETVAIPVRVAP---EPAVASAA-PAPAAAPAAARLTPTEE 493
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
984-1072 |
4.61e-08 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 59.52 E-value: 4.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 984 PEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1063
Cdd:PRK12270 38 PGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDEV 117
|
90
....*....|
gi 2245149928 1064 EP-TSPAAAV 1072
Cdd:PRK12270 118 TPlRGAAAAV 127
|
|
| FRQ1 |
COG5126 |
Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]; |
3175-3233 |
4.71e-08 |
|
Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms];
Pssm-ID: 444056 [Multi-domain] Cd Length: 137 Bit Score: 54.41 E-value: 4.71e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 3175 DFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAAL 3233
Cdd:COG5126 37 TLFSEADTDGDGRISREEFVAGMESLFEATVEPFARAAFDLLDTDGDGKISADEFRRLL 95
|
|
| PRK10905 |
PRK10905 |
cell division protein DamX; Validated |
1018-1207 |
4.74e-08 |
|
cell division protein DamX; Validated
Pssm-ID: 236792 [Multi-domain] Cd Length: 328 Bit Score: 58.03 E-value: 4.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1018 AAVPTPEEPTSPAAAVPPPEEPTSPAAAvPTPEEPTSPAA---------------AVPTPEEPTSPAAAVPTPEEPTSPA 1082
Cdd:PRK10905 50 GVQPAPGTTSAEQTAGNTQQDVSLPPIS-STPTQGQTPVAtdgqqrvevqgdlnnALTQPQNQQQLNNVAVNSTLPTEPA 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1083 AAVPTPEEPTSPAAAVptpeEPTSPAAAVPTPE------EPASPAAAVPTPEEPaspaaavpTPEEPAFPAPAVPTPEES 1156
Cdd:PRK10905 129 TVAPVRNGNASRQTAK----TQTAERPATTRPArkqaviEPKKPQATAKTEPKP--------VAQTPKRTEPAAPVASTK 196
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2245149928 1157 ASAAVAVPTPEESASpAAAVPTPAesasfaavvatleeptsPAASVPTPAA 1207
Cdd:PRK10905 197 APAATSTPAPKETAT-TAPVQTAS-----------------PAQTTATPAA 229
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
824-1078 |
5.12e-08 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 58.96 E-value: 5.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 824 LEEWIPVLQRPSRTAAVPtvkDALDAAlpspeegtsiaAVPAPEGTAVVAALVPFPHEDILVASIVSLEEE-----DVTA 898
Cdd:PRK14951 287 LEEMAAVLQRMAVLQAVP---QAAAAA-----------TDPEAAEVARLAALMPADETQLLYSICLHGRAElglapDEYA 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 899 AAVSAPER--ATVPAVTVSVPeGTAAVAAVSSPEETAPAVAaaitqegmsavagfspewaalaitvpiteedgtpegPVT 976
Cdd:PRK14951 353 ALTMVLLRllAFKPAAAAEAA-APAEKKTPARPEAAAPAAA------------------------------------PVA 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 977 PATTVHAPEEPDTAAvrvsTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSP-AAAVPTPEEPtSP 1055
Cdd:PRK14951 396 QAAAAPAPAAAPAAA----ASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQAAPeTVAIPVRVAP-EP 470
|
250 260
....*....|....*....|...
gi 2245149928 1056 AAAVPTPEEPTSPAAAVPTPEEP 1078
Cdd:PRK14951 471 AVASAAPAPAAAPAAARLTPTEE 493
|
|
| PHA03291 |
PHA03291 |
envelope glycoprotein I; Provisional |
1005-1129 |
5.19e-08 |
|
envelope glycoprotein I; Provisional
Pssm-ID: 223033 [Multi-domain] Cd Length: 401 Bit Score: 58.43 E-value: 5.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1005 AAVPTPEEPTSPAAAVPTPEEPTSPAAavpPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1084
Cdd:PHA03291 164 AAFPAEGTLAAPPLGEGSADGSCDPAL---PLSAPRLGPADVFVPATPRPTPRTTASPETTPTPSTTTSPPSTTIPAPST 240
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 2245149928 1085 VPTPEEPTSpaaavpTPEEPTSPAAAVPTPEEpASPAAAVPTPEE 1129
Cdd:PHA03291 241 TIAAPQAGT------TPEAEGTPAPPTPGGGE-APPANATPAPEA 278
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
970-1176 |
5.27e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 58.95 E-value: 5.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 970 TPEGPvTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEptSPAAAVPTP 1049
Cdd:PRK08691 384 TAEKE-TAAKKPQPRPEAETAQTPVQTASAAAMPSEGKTAGPVSNQENNDVPPWEDAPDEAQTAAGTAQ--TSAKSIQTA 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1050 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPT-SPAAAVPTPEEPTSPAAAVPTPEEPtSPAAAVPTPEEPASPAAAVPTPE 1128
Cdd:PRK08691 461 SEAETPPENQVSKNKAADNETDAPLSEVPSeNPIQATPNDEAVETETFAHEAPAEP-FYGYGFPDNDCPPEDGAEIPPPD 539
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1129 -EPASPA-AAVPTPEEPAFPAPAVPTPEESAsaavavPTPEESASPAAAV 1176
Cdd:PRK08691 540 wEHAAPAdTAGGGADEEAEAGGIGGNNTPSA------PPPEFSTENWAAI 583
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
1106-1317 |
5.46e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 58.95 E-value: 5.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1106 SPAAAvptpeePASPAAAVPTPEEPASPAAAvpTPEEPAFPAPAVPTPEeSASAAVAVPTPEESA-SPAAAVPTPAESAS 1184
Cdd:PRK08691 359 APLAA------ASCDANAVIENTELQSPSAQ--TAEKETAAKKPQPRPE-AETAQTPVQTASAAAmPSEGKTAGPVSNQE 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1185 FAAVVATLEEPT---SPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPT-SPAAAVPT---LEEPTSS 1257
Cdd:PRK08691 430 NNDVPPWEDAPDeaqTAAGTAQTSAKSIQTASEAETPPENQVSKNKAADNETDAPLSEVPSeNPIQATPNdeaVETETFA 509
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1258 AAAVLTPEELSSPAAS----------VPTPEEPASPAAAVSNLEEPASPAAAVPTPevaaiPAASVPTPE 1317
Cdd:PRK08691 510 HEAPAEPFYGYGFPDNdcppedgaeiPPPDWEHAAPADTAGGGADEEAEAGGIGGN-----NTPSAPPPE 574
|
|
| PRK13108 |
PRK13108 |
prolipoprotein diacylglyceryl transferase; Reviewed |
1050-1260 |
5.47e-08 |
|
prolipoprotein diacylglyceryl transferase; Reviewed
Pssm-ID: 237284 [Multi-domain] Cd Length: 460 Bit Score: 58.45 E-value: 5.47e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1050 EEPTSPAAAVPTPEEPTSPaaavptpeEPTSPAAAVptpeepTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEE 1129
Cdd:PRK13108 280 EAPGALRGSEYVVDEALER--------EPAELAAAA------VASAASAVGPVGPGEPNQPDDVAEAVKAEVAEVTDEVA 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1130 PASPAAAVPTPEEPAfpapavPTPEESASAAVAVPTPEESASPAAAvpTPAESASFAAvvatlEEPTSPAASVPtpaamv 1209
Cdd:PRK13108 346 AESVVQVADRDGEST------PAVEETSEADIEREQPGDLAGQAPA--AHQVDAEAAS-----AAPEEPAALAS------ 406
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2245149928 1210 atlEEFTSPAASVPTSEEPaslaaaVSNPEEPTSPAAAVPTlEEPTSSAAA 1260
Cdd:PRK13108 407 ---EAHDETEPEVPEKAAP------IPDPAKPDELAVAGPG-DDPAEPDGI 447
|
|
| PRK10819 |
PRK10819 |
transport protein TonB; Provisional |
1047-1178 |
5.67e-08 |
|
transport protein TonB; Provisional
Pssm-ID: 236768 [Multi-domain] Cd Length: 246 Bit Score: 56.61 E-value: 5.67e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1047 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPE-EPtspaaaVPTPEeptspaaavPTPEEPTSPAAAVPTPEEPASPaaaVP 1125
Cdd:PRK10819 42 PAPAQPISVTMVAPADLEPPQAVQPPPEPVvEP------EPEPE---------PIPEPPKEAPVVIPKPEPKPKP---KP 103
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 2245149928 1126 TPE-EPASPAAAVPTPE-EPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPT 1178
Cdd:PRK10819 104 KPKpKPVKKVEEQPKREvKPVEPRPASPFENTAPARPTSSTATAAASKPVTSVSS 158
|
|
| PTZ00436 |
PTZ00436 |
60S ribosomal protein L19-like protein; Provisional |
983-1140 |
6.91e-08 |
|
60S ribosomal protein L19-like protein; Provisional
Pssm-ID: 185616 [Multi-domain] Cd Length: 357 Bit Score: 57.65 E-value: 6.91e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 983 APEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPeePTSPAAAVPTP 1062
Cdd:PTZ00436 197 AAAKQKAAAKKAAAPSGKKSAKAAAPAKAAAAPAKAAAPPAKAAAAPAKAAAAPAKAAAPPAKAAAP--PAKAAAPPAKA 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1063 EEPTSPAAAVPtpeeptSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPAS--PAAAVPTP 1140
Cdd:PTZ00436 275 AAPPAKAAAPP------AKAAAPPAKAAAAPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAATPPAKAAapPAKAAAAP 348
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1487-2107 |
6.93e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 58.98 E-value: 6.93e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1487 LADTEELIANQKppsaeYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEggriAQSAE-LADR-EKITGQLESLESRWTEL 1564
Cdd:pfam15921 94 LNESNELHEKQK-----FYLRQSVIDLQTKLQEMQMERDAMADIRRRE----SQSQEdLRNQlQNTVHELEAAKCLKEDM 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1565 LSKAAARQKQLEDILVLAKQ-FHETAEPISDFLSVTEKKLANSEPVGT----QTAKIQQQIIRHkaLNEEIVNRKKNVDQ 1639
Cdd:pfam15921 165 LEDSNTQIEQLRKMMLSHEGvLQEIRSILVDFEEASGKKIYEHDSMSTmhfrSLGSAISKILRE--LDTEISYLKGRIFP 242
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1640 AIKNGQALLKQTTGEEVLLIQEKLDGIKTRYAD----ITVTSSKALRTLEQARQLATKFQSTYEELTG----WLREVEE- 1710
Cdd:pfam15921 243 VEDQLEALKSESQNKIELLLQQHQDRIEQLISEheveITGLTEKASSARSQANSIQSQLEIIQEQARNqnsmYMRQLSDl 322
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1711 ELATSGGQSPTGEQipqfqQRQKELKKEVMEHRLVLDTvNEVSRALLELVPWRAREG-----LDKLVSDANEQYKLVS-- 1783
Cdd:pfam15921 323 ESTVSQLRSELREA-----KRMYEDKIEELEKQLVLAN-SELTEARTERDQFSQESGnlddqLQKLLADLHKREKELSle 396
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1784 ------------------DTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQ-DQTTAQLQVQKaf 1844
Cdd:pfam15921 397 keqnkrlwdrdtgnsitiDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKvSSLTAQLESTK-- 474
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1845 siDIIRhkDSMDELFSHRSeifgTCGEEQKTV------LQEKTESLIQQYEAISLLNSERYARLERAQVLVNQfwetYEE 1918
Cdd:pfam15921 475 --EMLR--KVVEELTAKKM----TLESSERTVsdltasLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNE----GDH 542
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1919 LSPWIEETRALIAQLPSPAIDHEQLRQQQEEMRQLresIAEHkphidkllkigpqlkelNPEEGEMVEEKyqkaenmyAQ 1998
Cdd:pfam15921 543 LRNVQTECEALKLQMAEKDKVIEILRQQIENMTQL---VGQH-----------------GRTAGAMQVEK--------AQ 594
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1999 IKEEVRQRALALDE----AVSQSTQITEFHDKIEPM-LETLENL---SSRLRMPPLIPAEVDKIrecISDNKSATVELEK 2070
Cdd:pfam15921 595 LEKEINDRRLELQEfkilKDKKDAKIRELEARVSDLeLEKVKLVnagSERLRAVKDIKQERDQL---LNEVKTSRNELNS 671
|
650 660 670 680
....*....|....*....|....*....|....*....|.
gi 2245149928 2071 LQPSFEALKR----RGEELIGRSQGADKDLaaKEIQDKLDQ 2107
Cdd:pfam15921 672 LSEDYEVLKRnfrnKSEEMETTTNKLKMQL--KSAQSELEQ 710
|
|
| PHA03291 |
PHA03291 |
envelope glycoprotein I; Provisional |
1000-1103 |
7.23e-08 |
|
envelope glycoprotein I; Provisional
Pssm-ID: 223033 [Multi-domain] Cd Length: 401 Bit Score: 58.04 E-value: 7.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1000 PASPAAAVPTPEEPTSPAAAVPTPE-EPTS---PAAAVPPPEEPTSPAAAvPTPEEPTSPAAAVPTPEEPTSPA-AAVPT 1074
Cdd:PHA03291 172 LAAPPLGEGSADGSCDPALPLSAPRlGPADvfvPATPRPTPRTTASPETT-PTPSTTTSPPSTTIPAPSTTIAApQAGTT 250
|
90 100
....*....|....*....|....*....
gi 2245149928 1075 PEEPTSPAAAVPTPEEpTSPAAAVPTPEE 1103
Cdd:PHA03291 251 PEAEGTPAPPTPGGGE-APPANATPAPEA 278
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
1198-1316 |
7.39e-08 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 58.57 E-value: 7.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1198 PAASVPTPAAmvatleeftSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTP 1277
Cdd:PRK14951 366 PAAAAEAAAP---------AEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAA 436
|
90 100 110
....*....|....*....|....*....|....*....
gi 2245149928 1278 EEPASPAAAvsnleEPASPAAAVPTPEVAAIPAASVPTP 1316
Cdd:PRK14951 437 APAAAPAAV-----ALAPAPPAQAAPETVAIPVRVAPEP 470
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
1879-2432 |
7.77e-08 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 58.58 E-value: 7.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1879 EKTESLIQQYEAiSLLNSERYARLERAQVLVNQfwETYEELSPWIEETRALIAQLPSPA-IDHEQLRQQQEEMRQLRESI 1957
Cdd:pfam05483 222 EKIQHLEEEYKK-EINDKEKQVSLLLIQITEKE--NKMKDLTFLLEESRDKANQLEEKTkLQDENLKELIEKKDHLTKEL 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1958 AEHKPHIDKLLKIGPQLKE----------LNPEEGEMVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFH-DK 2026
Cdd:pfam05483 299 EDIKMSLQRSMSTQKALEEdlqiatkticQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNeDQ 378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2027 IEPMLETLENLSSRLR-MPPLI---PAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQ 2102
Cdd:pfam05483 379 LKIITMELQKKSSELEeMTKFKnnkEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQ 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2103 ---DKLDQMVFFWE--DIKARAEEREIKFLDVLELAEKFWYDMAALlttIKDTQDIVHDLESPGIDPSIIKQQVE----A 2173
Cdd:pfam05483 459 ltaIKTSEEHYLKEveDLKTELEKEKLKNIELTAHCDKLLLENKEL---TQEASDMTLELKKHQEDIINCKKQEErmlkQ 535
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2174 AETIKEETDGLHEELEFIR---ILGADLIfACGETEKPEVRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQ 2250
Cdd:pfam05483 536 IENLEEKEMNLRDELESVReefIQKGDEV-KCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELH 614
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2251 AmfdwlDNTVIKLCTMPPvGTDLNTVKDQLNEMkEFKVEVYQQQIEMEKLNHQGELMLKKATDETdrdiIREPLTELKHL 2330
Cdd:pfam05483 615 Q-----ENKALKKKGSAE-NKQLNAYEIKVNKL-ELELASAKQKFEEIIDNYQKEIEDKKISEEK----LLEEVEKAKAI 683
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2331 WE---NLGEKIAHR-QHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKV-IEVELAKhhvLKNDVLAHQA 2405
Cdd:pfam05483 684 ADeavKLQKEIDKRcQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAaLEIELSN---IKAELLSLKK 760
|
570 580
....*....|....*....|....*..
gi 2245149928 2406 TVEtVNKAGNELLESSAGDDASSLRSR 2432
Cdd:pfam05483 761 QLE-IEKEEKEKLKMEAKENTAILKDK 786
|
|
| PHA03169 |
PHA03169 |
hypothetical protein; Provisional |
966-1138 |
8.93e-08 |
|
hypothetical protein; Provisional
Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 57.67 E-value: 8.93e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 966 EEDGTPEGP-------VTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPP--- 1035
Cdd:PHA03169 87 RGQGGPSGSgsesvgsPTPSPSGSAEELASGLSPENTSGSSPESPASHSPPPSPPSHPGPHEPAPPESHNPSPNQQPssf 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1036 --PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAavPTPEEPTSP--AAAVPTPEEPTSPAAAV 1111
Cdd:PHA03169 167 lqPSHEDSPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQS--PTPQQAPSPntQQAVEHEDEPTEPEREG 244
|
170 180
....*....|....*....|....*..
gi 2245149928 1112 PTPEEPASPAAAVpTPEEPASPAAAVP 1138
Cdd:PHA03169 245 PPFPGHRSHSYTV-VGWKPSTRPGGVP 270
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1837-2518 |
9.51e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 58.53 E-value: 9.51e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1837 QLQVQKA----------FSIDIIRHKDSMDELFSHRSEIFGTcgEEQKTVLQEKTESLIQQYEA-ISLLNSERYARLERA 1905
Cdd:TIGR02168 206 ERQAEKAerykelkaelRELELALLVLRLEELREELEELQEE--LKEAEEELEELTAELQELEEkLEELRLEVSELEEEI 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1906 QVLVNQFWETYEELSpwIEETRALIAQlpspaidhEQLRQQQEEMRQLRESIAEHKPHIDKLLK----IGPQLKELNPE- 1980
Cdd:TIGR02168 284 EELQKELYALANEIS--RLEQQKQILR--------ERLANLERQLEELEAQLEELESKLDELAEelaeLEEKLEELKEEl 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1981 -----EGEMVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEfhdKIEPMLETLENLSSRL---------RMPPL 2046
Cdd:TIGR02168 354 esleaELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN---EIERLEARLERLEDRRerlqqeieeLLKKL 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2047 IPAEVDKIRECISDNKSatvELEKLQPSFEALKRRGEELIGRSQGADKDL-AAKEIQDKLDQMVFFWEDIKARAEE--RE 2123
Cdd:TIGR02168 431 EEAELKELQAELEELEE---ELEELQEELERLEEALEELREELEEAEQALdAAERELAQLQARLDSLERLQENLEGfsEG 507
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2124 IKFL---------------DVLELAEKFwydMAALLTTI-KDTQDIVHDLESpgidpsiikQQVEAAETIKEETDGLHEE 2187
Cdd:TIGR02168 508 VKALlknqsglsgilgvlsELISVDEGY---EAAIEAALgGRLQAVVVENLN---------AAKKAIAFLKQNELGRVTF 575
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2188 LEFIRILGADLIFACGETEKPE-----VRKSIDEMNNAWENLNKTWKERL---EKLEDAMQAAVQYQdtLQAMFDWLDNT 2259
Cdd:TIGR02168 576 LPLDSIKGTEIQGNDREILKNIegflgVAKDLVKFDPKLRKALSYLLGGVlvvDDLDNALELAKKLR--PGYRIVTLDGD 653
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2260 VIK---LCTMPPVGTDLNTV------KDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATD-ETDRDIIREPLTELKH 2329
Cdd:TIGR02168 654 LVRpggVITGGSAKTNSSILerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQlRKELEELSRQISALRK 733
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2330 LWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQrpisgdpkviEVELAKhhvLKNDVLAHQATVET 2409
Cdd:TIGR02168 734 DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA----------EAEIEE---LEAQIEQLKEELKA 800
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2410 VNKAGNELLE--SSAGDDASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQL-SASK 2486
Cdd:TIGR02168 801 LREALDELRAelTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELeALLN 880
|
730 740 750
....*....|....*....|....*....|..
gi 2245149928 2487 ptggLPETAREQLDTHMELYSQLKAKEETYNQ 2518
Cdd:TIGR02168 881 ----ERASLEEALALLRSELEELSEELRELES 908
|
|
| PRK10905 |
PRK10905 |
cell division protein DamX; Validated |
1031-1237 |
9.58e-08 |
|
cell division protein DamX; Validated
Pssm-ID: 236792 [Multi-domain] Cd Length: 328 Bit Score: 56.87 E-value: 9.58e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1031 AAVPPPEEPTSPAAAVPTPEEPT-SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1109
Cdd:PRK10905 50 GVQPAPGTTSAEQTAGNTQQDVSlPPISSTPTQGQTPVATDGQQRVEVQGDLNNALTQPQNQQQLNNVAVNSTLPTEPAT 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1110 AVPTPEEPASPAAAVptpeEPASPAAAVPTPE------EPAFPAPAVPTPEESASAAvavPTPEESASPAAAVPTPAESA 1183
Cdd:PRK10905 130 VAPVRNGNASRQTAK----TQTAERPATTRPArkqaviEPKKPQATAKTEPKPVAQT---PKRTEPAAPVASTKAPAATS 202
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 1184 SFAAvvatleEPTSPAASVPTPAAMVATleefTSPAASVPTSEEPASLAAAVSN 1237
Cdd:PRK10905 203 TPAP------KETATTAPVQTASPAQTT----ATPAAGGKTAGNVGSLKSAPSS 246
|
|
| KREPA2 |
cd23959 |
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of ... |
991-1204 |
9.92e-08 |
|
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of the parasitic protozoan's KREPA RNA editing catalytic complex (RECC). Kinetoplastid RNA editing (KRE) proteins occur as pairs or sets of related proteins in multiple complexes. KREPA complex is composed of six components (KREPA1-6), which share a conserved C-terminal region containing an oligonucleotide-binding (OB)-fold-like domain. KREPAs are responsible for the site-specific insertion and deletion of U nucleotides in the kinetoplastid mitochondria pre-messenger RNA. Apart from the conserved C-terminal OB-fold domain, KREPA1, KREPA2, and KREPA3 contain two conserved C2H2 zinc-finger domains. KREPA2 and kinetoplastid RNA editing ligase 1 (KREL1) are specific for ligation post-U-deletion and are paralogous to KREL2 and KREPA1 that are specific for ligation post-U-insertion. KREPA2, is critical for RECC stability and KREL1 integration into the complex.
Pssm-ID: 467780 [Multi-domain] Cd Length: 424 Bit Score: 57.57 E-value: 9.92e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 991 AVRVSTPEEPaspaaavptPEEPTSPAAAvPTPEEPTSPAAAVPPPEEPTSPA--------AAVPTPEEPTSP--AAAVP 1060
Cdd:cd23959 47 AARPSDQEEP---------LYGAVSPEGE-NPFDGPGLVTASTVSDCYVGNANfyevdmsdAFAMAPDESLGPfrAARVP 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1061 TP-EEPTSPAAAVPTPEEPTSPAAAVPTPeePTSPAAAVPTPEEpTSPAAAVPTPEEPASPAAAVPTpeEPASPAAAVPT 1139
Cdd:cd23959 117 NPfSASSSTQRETHKTAQVAPPKAEPQTA--PVTPFGQLPMFGQ-HPPPAKPLPAAAAAQQSSASPG--EVASPFASGTV 191
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1140 PEEP-AFPAPAVPTPEESASAAVAVptpeESASPAAAvptPAESASFAAVVATLEEPTSPAASVPT 1204
Cdd:cd23959 192 SASPfATATDTAPSSGAPDGFPAEA----SAPSPFAA---PASAASFPAAPVANGEAATPTHACTI 250
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
992-1180 |
1.05e-07 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 57.91 E-value: 1.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 992 VRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPeePTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAvPTPEEPTSPAAA 1071
Cdd:PRK14086 82 IRIAITVDPSAGEPAPPPPHARRTSEPELPRP--GRRPYEGYGGPRADDRPPGLPRQDQLPTARPAY-PAYQQRPEPGAW 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1072 VPTPEE--PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEepafPAPA 1149
Cdd:PRK14086 159 PRAADDygWQQQRLGFPPRAPYASPASYAPEQERDREPYDAGRPEYDQRRRDYDHPRPDWDRPRRDRTDRPE----PPPG 234
|
170 180 190
....*....|....*....|....*....|....*..
gi 2245149928 1150 VPTPEESASAAVAVPTPEESA------SPAAAVPTPA 1180
Cdd:PRK14086 235 AGHVHRGGPGPPERDDAPVVPirpsapGPLAAQPAPA 271
|
|
| KLF9_13_N-like |
cd21975 |
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like ... |
990-1135 |
1.16e-07 |
|
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like transcription factors (KLFs) belong to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the related N-terminal domains of KLF9, KLF13, KLF14, KLF16, and similar proteins.
Pssm-ID: 409240 [Multi-domain] Cd Length: 163 Bit Score: 54.31 E-value: 1.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 990 AAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPT--------SPAAAVPTPEEPTSPAAAVPT 1061
Cdd:cd21975 15 GAVVHGVRPDPEGAGLAAGLDVRATREVAKGPGPPGPAWKPDGADSPGLVTaaphllaaNVLAPLRGPSVEGSSLESGDA 94
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 1062 PEEPTSPAAAVPTPEEPTSPAAavptpeepTSPAAAVPTPEEPTSPAAAVPTPEEPAsPAAAVPTPEEPASPAA 1135
Cdd:cd21975 95 DMGSDSDVAPASGAAASTSPES--------SSDAASSPSPLSLLHPGEAGLEPERPR-PRVRRGVRRRGVTPAA 159
|
|
| PRK11633 |
PRK11633 |
cell division protein DedD; Provisional |
966-1069 |
1.20e-07 |
|
cell division protein DedD; Provisional
Pssm-ID: 236940 [Multi-domain] Cd Length: 226 Bit Score: 55.39 E-value: 1.20e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 966 EEDGTPegPVTPATTVHAPEEpDTAAVRVSTPEEPASPAAAVPTPEEPTSPAaavPTPEEPTSPAAAVPPPEEPTSPAAA 1045
Cdd:PRK11633 52 EPDMMP--AATQALPTQPPEG-AAEAVRAGDAAAPSLDPATVAPPNTPVEPE---PAPVEPPKPKPVEKPKPKPKPQQKV 125
|
90 100
....*....|....*....|....
gi 2245149928 1046 VPTPEEPTSPAaavPTPEEPTSPA 1069
Cdd:PRK11633 126 EAPPAPKPEPK---PVVEEKAAPT 146
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
1105-1240 |
1.23e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 57.51 E-value: 1.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1105 TSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEesasaavaVPTPEESASPaaaVPTPAESAs 1184
Cdd:PRK14950 361 VPVPAPQPAKPTAAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPP--------PVPPRPVAPP---VPHTPESA- 428
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1185 faavvatleePTSPAASVPTPAAMVATleeftspaASVPTSEEPASLAAAVSNPEE 1240
Cdd:PRK14950 429 ----------PKLTRAAIPVDEKPKYT--------PPAPPKEEEKALIADGDVLEQ 466
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1438-2028 |
1.24e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 58.06 E-value: 1.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1438 VQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEEL-IANQKPPS---------AEYKVV 1507
Cdd:TIGR00618 302 VTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIrDAHEVATSireiscqqhTLTQHI 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1508 KAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAqsAELADREKITGQLESLESrwTELLSKAAARQKQLEDILVLAKQFHE 1587
Cdd:TIGR00618 382 HTLQQQKTTLTQKLQSLCKELDILQREQATID--TRTSAFRDLQGQLAHAKK--QQELQQRYAELCAAAITCTAQCEKLE 457
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1588 TAEPISDFLSVTEK--KLANSEpvgtqtaKIQQQIIRHKALNEEIVNRKKnvdqaiKNGQALLKQTTGEEVLLIQEKLDG 1665
Cdd:TIGR00618 458 KIHLQESAQSLKEReqQLQTKE-------QIHLQETRKKAVVLARLLELQ------EEPCPLCGSCIHPNPARQDIDNPG 524
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1666 iktryaditVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEElatsggqsptGEQIPQFQQRQKELKKEVMEHRLV 1745
Cdd:TIGR00618 525 ---------PLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASL----------KEQMQEIQQSFSILTQCDNRSKED 585
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1746 LDTVNEVSRALLELVPWRAREGLDKLVSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALG 1825
Cdd:TIGR00618 586 IPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHAL 665
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1826 PIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRSEIFgtcgEEQKTVLQEktesLIQQYEAISLLNSERYARLERA 1905
Cdd:TIGR00618 666 SIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLL----RELETHIEE----YDREFNEIENASSSLGSDLAAR 737
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1906 QVLVNQFWETYEELSPWIEETRALIAQLPSPAI----------------DHEQLRQQQEEMRQLRESIAEHKPHIDKLLK 1969
Cdd:TIGR00618 738 EDALNQSLKELMHQARTVLKARTEAHFNNNEEVtaalqtgaelshlaaeIQFFNRLREEDTHLLKTLEAEIGQEIPSDED 817
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2245149928 1970 IGPQLKELNPEEGEMVEEKYQKAENMYAQIK------EEVRQRalaLDEAVSQSTQITEFHDKIE 2028
Cdd:TIGR00618 818 ILNLQCETLVQEEEQFLSRLEEKSATLGEIThqllkyEECSKQ---LAQLTQEQAKIIQLSDKLN 879
|
|
| EH |
cd00052 |
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and ... |
3175-3234 |
1.46e-07 |
|
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A hydrophobic binding pocket is formed by residues from both EF-hand motifs. The EH domain binds to proteins containing NPF (class I), [WF]W or SWG (class II), or H[TS]F (class III) sequence motifs.
Pssm-ID: 238009 [Multi-domain] Cd Length: 67 Bit Score: 50.68 E-value: 1.46e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 3175 DFFRRIDKDQDGKITRQEFIDGILASKFPTTKLemtavADIF---DRDGDGYIDYYEFVAALH 3234
Cdd:cd00052 3 QIFRSLDPDGDGLISGDEARPFLGKSGLPRSVL-----AQIWdlaDTDKDGKLDKEEFAIAMH 60
|
|
| PTZ00436 |
PTZ00436 |
60S ribosomal protein L19-like protein; Provisional |
1069-1234 |
1.55e-07 |
|
60S ribosomal protein L19-like protein; Provisional
Pssm-ID: 185616 [Multi-domain] Cd Length: 357 Bit Score: 56.50 E-value: 1.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1069 AAAVPTPEEPTSPAAAVPTPEEptSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPeePAfPAP 1148
Cdd:PTZ00436 194 AAAAAAKQKAAAKKAAAPSGKK--SAKAAAPAKAAAAPAKAAAPPAKAAAAPAKAAAAPAKAAAPPAKAAAP--PA-KAA 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1149 AVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATleeptSPAASVPTPAAMVATLEEFTSPAASVPTSeeP 1228
Cdd:PTZ00436 269 APPAKAAAPPAKAAAPPAKAAAPPAKAAAAPAKAAAAPAKAAA-----APAKAAAPPAKAAAPPAKAATPPAKAAAP--P 341
|
....*.
gi 2245149928 1229 ASLAAA 1234
Cdd:PTZ00436 342 AKAAAA 347
|
|
| PTZ00436 |
PTZ00436 |
60S ribosomal protein L19-like protein; Provisional |
1017-1184 |
1.60e-07 |
|
60S ribosomal protein L19-like protein; Provisional
Pssm-ID: 185616 [Multi-domain] Cd Length: 357 Bit Score: 56.50 E-value: 1.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1017 AAAVPTPEEPTSPAAAVPPPEEPTSPAAAvptpeePTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1096
Cdd:PTZ00436 193 AAAAAAAKQKAAAKKAAAPSGKKSAKAAA------PAKAAAAPAKAAAPPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAK 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1097 AVPTPEEPTSPAAAVPTPeePASPAAAvptpeePASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAV 1176
Cdd:PTZ00436 267 AAAPPAKAAAPPAKAAAP--PAKAAAP------PAKAAAAPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAATPPAKAA 338
|
....*...
gi 2245149928 1177 PTPAESAS 1184
Cdd:PTZ00436 339 APPAKAAA 346
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1169-1363 |
1.62e-07 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 57.62 E-value: 1.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1169 SASPAAAVPTPA-ESASFAAVVATLEEPTSpaASVPTpaamvatleEFTSPAASVPT-------SEEPASLAAAVSNPEE 1240
Cdd:pfam05109 422 SKAPESTTTSPTlNTTGFAAPNTTTGLPSS--THVPT---------NLTAPASTGPTvstadvtSPTPAGTTSGASPVTP 490
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1241 PTSP-----AAAVPTLEEPTSsaaAVLTPeelsSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTP---EVAAIPAAS 1312
Cdd:pfam05109 491 SPSPrdngtESKAPDMTSPTS---AVTTP----TPNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTPtpnATSPTPAVT 563
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1313 VPTPEVPaipaaavppmeevspigVPFLGVSAHTDSV--PISEEGTPVLEEAS 1363
Cdd:pfam05109 564 TPTPNAT-----------------IPTLGKTSPTSAVttPTPNATSPTVGETS 599
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
1000-1158 |
1.86e-07 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 57.28 E-value: 1.86e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1000 PASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP---- 1075
Cdd:PRK14948 361 PSAFISEIANASAPANPTPAPNPSPPPAPIQPSAPKTKQAATTPSPPPAKASPPIPVPAEPTEPSPTPPANAANAPpsln 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1076 ------------EEPT-------------------------------------------------------------SPA 1082
Cdd:PRK14948 441 leelwqqilaklELPStrmllsqqaelvsldsnraviavspnwlgmvqsrkplleqafakvlgrsiklnlesqsgsaSNT 520
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1083 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAvPTPEESAS 1158
Cdd:PRK14948 521 AKTPPPPQKSPPPPAPTPPLPQPTATAPPPTPPPPPPTATQASSNAPAQIPADSSPPPPIPEEPTPS-PTKDSSPE 595
|
|
| PHA03291 |
PHA03291 |
envelope glycoprotein I; Provisional |
1070-1286 |
2.11e-07 |
|
envelope glycoprotein I; Provisional
Pssm-ID: 223033 [Multi-domain] Cd Length: 401 Bit Score: 56.50 E-value: 2.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1070 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE-EPTS---PAAAVPTPEEPASPAAAvPTPEEPASPAAAVPTPEEPAF 1145
Cdd:PHA03291 164 AAFPAEGTLAAPPLGEGSADGSCDPALPLSAPRlGPADvfvPATPRPTPRTTASPETT-PTPSTTTSPPSTTIPAPSTTI 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1146 PAP-AVPTPEESASAAVAVPTPEEsASPAAAVPTPAESaSFAAVVATLEEPTSPAASV--------------------PT 1204
Cdd:PHA03291 243 AAPqAGTTPEAEGTPAPPTPGGGE-APPANATPAPEAS-RYELTVTQIIQIAIPASIIacvflgscacclhrrcrrrrRR 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1205 PAAMVATleefTSPAASVPTSEEPASLA----AAVSNPEEPTSPAAAVPTlEEPTSSAAAVltpEELSSPAASVPTPEEP 1280
Cdd:PHA03291 321 PARIYRP----PSPVAPSISAVNEAALArlgdELKRHPPESPRRSKRRSS-QTMVPSLTAI---SEESEAPAVVELSRSP 392
|
....*.
gi 2245149928 1281 ASPAAA 1286
Cdd:PHA03291 393 RRPGGP 398
|
|
| DUF3729 |
pfam12526 |
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ... |
1008-1088 |
2.13e-07 |
|
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.
Pssm-ID: 372164 [Multi-domain] Cd Length: 115 Bit Score: 52.00 E-value: 2.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1008 PTPEEPTSPAAAvPTPEEPTSPAAAVPPPEEPTSPAAavPTPEEPTSPAAAVPTPEEPTSPaaavPTPEEPTSPAAAVPT 1087
Cdd:pfam12526 29 FSPPESAHPDPP-PPVGDPRPPVVDTPPPVSAVWVLP--PPSEPAAPEPDLVPPVTGPAGP----PSPLAPPAPAQKPPL 101
|
.
gi 2245149928 1088 P 1088
Cdd:pfam12526 102 P 102
|
|
| PHA02682 |
PHA02682 |
ORF080 virion core protein; Provisional |
1172-1385 |
2.34e-07 |
|
ORF080 virion core protein; Provisional
Pssm-ID: 177464 [Multi-domain] Cd Length: 280 Bit Score: 55.25 E-value: 2.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1172 PAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEepTSPAAAVPTL 1251
Cdd:PHA02682 30 PQATIPAPAAPCPPDADVDPLDKYSVKEAGRYYQSRLKANSACMQRPSGQSPLAPSPACAAPAPACPA--CAPAAPAPAV 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1252 EEPTSSAAAVLTPEELSSPAASVPTPEEPAsPAAAVSNLEEPASPAAAVPTPEVAAIPA---ASVPTPEVPAIPAAAVPP 1328
Cdd:PHA02682 108 TCPAPAPACPPATAPTCPPPAVCPAPARPA-PACPPSTRQCPPAPPLPTPKPAPAAKPIflhNQLPPPDYPAASCPTIET 186
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1329 MEEVSPIGVPflgvsahtdSVPiseegTPVLEEASSTGMWIKEDLDSLVFGIKEVTS 1385
Cdd:PHA02682 187 APAASPVLEP---------RIP-----DKIIDADNDDKDLIKKELADIADSVRDLNA 229
|
|
| DamX |
COG3266 |
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ... |
925-1207 |
2.41e-07 |
|
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442497 [Multi-domain] Cd Length: 455 Bit Score: 56.40 E-value: 2.41e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 925 AVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPItEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPA 1004
Cdd:COG3266 73 ALASAALLLALASLALLGILLLALLALLLDLLLLADLLRA-AALLLLKLLLLLLTLLLLVLLLLLALLLALLLDLPLLTL 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1005 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1084
Cdd:COG3266 152 LIVLPLLEEQLLLLALQDIQGTLQALGAVAALLGLRKAEEALALRAGSAAADALALLLLLLASALGEAVAAAAELAALAL 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1085 VPTPEEPTSPAAAVPT-------PEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESA 1157
Cdd:COG3266 232 LAAGAAEVLTARLVLLlliigsaLKAPSQASSASAPATTSLGEQQEVSLPPAVAAQPAAAAAAQPSAVALPAAPAAAAAA 311
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1158 SAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAA 1207
Cdd:COG3266 312 AAPAEAAAPQPTAAKPVVTETAAPAAPAPEAAAAAAAPAAPAVAKKLAAD 361
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
1004-1086 |
3.04e-07 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 55.42 E-value: 3.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1004 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1083
Cdd:PRK10856 169 TTDPATTPAPAAPVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPSQANVDTAATPAPAAPATPDGAAPLPTDQAGVSTPA 248
|
...
gi 2245149928 1084 AVP 1086
Cdd:PRK10856 249 ADP 251
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
2244-2346 |
3.08e-07 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 51.17 E-value: 3.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2244 QYQDTLQAMFDWLDNTVIKLcTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRdiIREP 2323
Cdd:pfam00435 5 QFFRDADDLESWIEEKEALL-SSEDYGKDLESVQALLKKHKALEAELAAHQDRVEALNELAEKLIDEGHYASEE--IQER 81
|
90 100
....*....|....*....|...
gi 2245149928 2324 LTELKHLWENLGEKIAHRQHKLE 2346
Cdd:pfam00435 82 LEELNERWEQLLELAAERKQKLE 104
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
967-1059 |
3.09e-07 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 56.82 E-value: 3.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 967 EDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAV 1046
Cdd:PRK12270 34 ADYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAV 113
|
90
....*....|....
gi 2245149928 1047 PTPEEP-TSPAAAV 1059
Cdd:PRK12270 114 EDEVTPlRGAAAAV 127
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
971-1143 |
3.16e-07 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 56.37 E-value: 3.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 971 PEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAA--AVPTPEEPTSPAAAVPTPEE--PTSPAAAVPPPEEPTSPAAAV 1046
Cdd:PRK14086 108 PELPRPGRRPYEGYGGPRADDRPPGLPRQDQLPTArpAYPAYQQRPEPGAWPRAADDygWQQQRLGFPPRAPYASPASYA 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1047 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPtsPAAAVPtPEEPTSPAAAVPTPEEPASPAAAVPT 1126
Cdd:PRK14086 188 PEQERDREPYDAGRPEYDQRRRDYDHPRPDWDRPRRDRTDRPEPP--PGAGHV-HRGGPGPPERDDAPVVPIRPSAPGPL 264
|
170
....*....|....*..
gi 2245149928 1127 PEEPASpaaaVPTPEEP 1143
Cdd:PRK14086 265 AAQPAP----APGPGEP 277
|
|
| DUF3729 |
pfam12526 |
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ... |
997-1075 |
3.20e-07 |
|
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.
Pssm-ID: 372164 [Multi-domain] Cd Length: 115 Bit Score: 51.62 E-value: 3.20e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 997 PEEPASPAAAvPTPEEPTSPAAAVPTPEEPTSPAAavPPPEEPTSPAAAVPTPEEPTSPaaavPTPEEPTSPAAAVPTP 1075
Cdd:pfam12526 31 PPESAHPDPP-PPVGDPRPPVVDTPPPVSAVWVLP--PPSEPAAPEPDLVPPVTGPAGP----PSPLAPPAPAQKPPLP 102
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
837-1113 |
3.50e-07 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 56.09 E-value: 3.50e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 837 TAAVPTVKDALDAALPS--PEEGTSIAA-VPAPEGTAVVAALVPFPHEDILVA---SIVSLEEEDVTAAAVSAPERATVP 910
Cdd:PLN03209 309 TTAPLTPMEELLAKIPSqrVPPKESDAAdGPKPVPTKPVTPEAPSPPIEEEPPqpkAVVPRPLSPYTAYEDLKPPTSPIP 388
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 911 AVTVSVPEGTAAVAAVSSPEETAPAVAAAITqegmsavagfspewAALAITVPITEEDGTpEGPVTPATTVHAPEEPDTA 990
Cdd:PLN03209 389 TPPSSSPASSKSVDAVAKPAEPDVVPSPGSA--------------SNVPEVEPAQVEAKK-TRPLSPYARYEDLKPPTSP 453
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 991 AvrvSTPEEPASPAAAVpTPEEPTSPAAAVPTPEepTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1070
Cdd:PLN03209 454 S---PTAPTGVSPSVSS-TSSVPAVPDTAPATAA--TDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTN 527
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1071 AVPTPEEPTSPAAAV-------PTPeEPTSPAAAVPTPEEPTSPAAAVPT 1113
Cdd:PLN03209 528 EVVKVGNSAPPTALAdeqhhaqPKP-RPLSPYTMYEDLKPPTSPTPSPVL 576
|
|
| PPE |
COG5651 |
PPE-repeat protein [Function unknown]; |
989-1209 |
3.55e-07 |
|
PPE-repeat protein [Function unknown];
Pssm-ID: 444372 [Multi-domain] Cd Length: 385 Bit Score: 55.67 E-value: 3.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 989 TAAVRvSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEP-------TSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPT 1061
Cdd:COG5651 159 AAAVA-LTPFTQPPPTITNPGGLLGAQNAGSGNTSSNPgfanlglTGLNQVGIGGLNSGSGPIGLNSGPGNTGFAGTGAA 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1062 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPE 1141
Cdd:COG5651 238 AGAAAAAAAAAAAAGAGASAALASLAATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAAATGLGLGAGGAAG 317
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 1142 EPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMV 1209
Cdd:COG5651 318 AAGATGAGAALGAGAAAAAAGAAAGAGAAAAAAAGGAGGGGGGALGAGGGGGSAGAAAGAASGGGAAA 385
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
964-1103 |
3.64e-07 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 55.16 E-value: 3.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 964 ITEEDGTPEGPVTP------ATTVHAPEEPDTAAVRVSTPEEPASPAAA----VPTPEEPTSPAAAVPTPEEPTSPAAAV 1033
Cdd:NF040712 188 IDPDFGRPLRPLATvprlarEPADARPEEVEPAPAAEGAPATDSDPAEAgtpdDLASARRRRAGVEQPEDEPVGPGAAPA 267
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1034 PPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPtSP--AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1103
Cdd:NF040712 268 AEPDEATRDAGEPPAPGAAETPEAAEPPAPAP-AApaAPAAPEAEEPARPEPPPAPKPKRRRRRASVPSWDD 338
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1547-2353 |
3.72e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.60 E-value: 3.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1547 REKITGQLESLES------RWTELlsKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEpvgTQTAKIQQQI 1620
Cdd:TIGR02168 195 LNELERQLKSLERqaekaeRYKEL--KAELRELELALLVLRLEELREELEELQEELKEAEEELEELT---AELQELEEKL 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1621 IRHKALNEEiVNRKKNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEE 1700
Cdd:TIGR02168 270 EELRLEVSE-LEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1701 LTGWLREVEEELATSGGQSPTGEQIPQFQQRQKE-LKKEVMEHRLVLDTV-NEVSRALLELVpwRAREGLDKLVSDANEQ 1778
Cdd:TIGR02168 349 LKEELESLEAELEELEAELEELESRLEELEEQLEtLRSKVAQLELQIASLnNEIERLEARLE--RLEDRRERLQQEIEEL 426
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1779 YKLVS----DTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMAlgpIRLEQDQTTAQLQVQKAFSIDIIRHKDS 1854
Cdd:TIGR02168 427 LKKLEeaelKELQAELEELEEELEELQEELERLEEALEELREELEEAEQ---ALDAAERELAQLQARLDSLERLQENLEG 503
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1855 MDE----LFSHRSEIFGTCGeeqktVLQEKTESLiQQYE-AISLLNSERyarleRAQVLV---NQFWETYEELSPwIEET 1926
Cdd:TIGR02168 504 FSEgvkaLLKNQSGLSGILG-----VLSELISVD-EGYEaAIEAALGGR-----LQAVVVenlNAAKKAIAFLKQ-NELG 571
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1927 RALIAQLPS-----PAIDHEQLRQQQEEMRQLRESIAEHKPHIDKLLkiGPQLkelnpeEGEMVEEKYQKAENMYAQIKE 2001
Cdd:TIGR02168 572 RVTFLPLDSikgteIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAL--SYLL------GGVLVVDDLDNALELAKKLRP 643
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2002 E----------VRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRmppLIPAEVDKIREcisdnksatvELEKL 2071
Cdd:TIGR02168 644 GyrivtldgdlVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIA---ELEKALAELRK----------ELEEL 710
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2072 QPSFEALKRRGEELIGRSQGADKDLAA--KEIQDKLDQMVFFWEDIKARAEEREIKFLDVLELAEKFwydmAALLTTIKd 2149
Cdd:TIGR02168 711 EEELEQLRKELEELSRQISALRKDLARleAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL----AEAEAEIE- 785
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2150 tqdivhDLESPgidpsiIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACG--ETEKPEVRKSIDEMNNAWENLNkt 2227
Cdd:TIGR02168 786 ------ELEAQ------IEQLKEELKALREALDELRAELTLLNEEAANLRERLEslERRIAATERRLEDLEEQIEELS-- 851
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2228 wkERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCT-MPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGEL 2306
Cdd:TIGR02168 852 --EDIESLAAEIEELEELIEELESELEALLNERASLEEaLALLRSELEELSEELRELESKRSELRRELEELREKLAQLEL 929
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 2307 MLKKAtdETDRDIIREPLTE-----------LKHLWENLGEKIAHRQHKLEGALLALG 2353
Cdd:TIGR02168 930 RLEGL--EVRIDNLQERLSEeysltleeaeaLENKIEDDEEEARRRLKRLENKIKELG 985
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
1584-1685 |
3.80e-07 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 50.79 E-value: 3.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1584 QFHETAEPISDFLSVTEKKLAnSEPVGTQTAKIQQQIIRHKALNEEIVNRKKNVDQAIKNGQALLKQtTGEEVLLIQEKL 1663
Cdd:smart00150 2 QFLRDADELEAWLEEKEQLLA-SEDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEE-GHPDAEEIEERL 79
|
90 100
....*....|....*....|..
gi 2245149928 1664 DGIKTRYADITVTSSKALRTLE 1685
Cdd:smart00150 80 EELNERWEELKELAEERRQKLE 101
|
|
| PRK13108 |
PRK13108 |
prolipoprotein diacylglyceryl transferase; Reviewed |
1036-1207 |
4.04e-07 |
|
prolipoprotein diacylglyceryl transferase; Reviewed
Pssm-ID: 237284 [Multi-domain] Cd Length: 460 Bit Score: 55.76 E-value: 4.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1036 PEEPTSPAAAVPTPEEPTSPAAAVPTpeepTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1115
Cdd:PRK13108 282 PGALRGSEYVVDEALEREPAELAAAA----VASAASAVGPVGPGEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADRDG 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1116 EPAspaaavPTPEEPASPAAAVPTPEEPAFPAPAvpTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEP 1195
Cdd:PRK13108 358 EST------PAVEETSEADIEREQPGDLAGQAPA--AHQVDAEAASAAPEEPAALASEAHDETEPEVPEKAAPIPDPAKP 429
|
170
....*....|..
gi 2245149928 1196 TSPAASVPTPAA 1207
Cdd:PRK13108 430 DELAVAGPGDDP 441
|
|
| PTZ00436 |
PTZ00436 |
60S ribosomal protein L19-like protein; Provisional |
1082-1249 |
4.16e-07 |
|
60S ribosomal protein L19-like protein; Provisional
Pssm-ID: 185616 [Multi-domain] Cd Length: 357 Bit Score: 55.34 E-value: 4.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1082 AAAVPTPEEPTSPAAAVPTPEEptSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFP---APAVPTPEESAS 1158
Cdd:PTZ00436 194 AAAAAAKQKAAAKKAAAPSGKK--SAKAAAPAKAAAAPAKAAAPPAKAAAAPAKAAAAPAKAAAPpakAAAPPAKAAAPP 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1159 AAVAVPTPEESASPAAAVPTPAESASFAAVVATleePTSPAASVPTPAAmvatleeftspAASVPTSEEPASLAAAVSNP 1238
Cdd:PTZ00436 272 AKAAAPPAKAAAPPAKAAAPPAKAAAAPAKAAA---APAKAAAAPAKAA-----------APPAKAAAPPAKAATPPAKA 337
|
170
....*....|.
gi 2245149928 1239 EEPTSPAAAVP 1249
Cdd:PTZ00436 338 AAPPAKAAAAP 348
|
|
| PBP1 |
COG5180 |
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ... |
782-1184 |
4.55e-07 |
|
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];
Pssm-ID: 444064 [Multi-domain] Cd Length: 548 Bit Score: 55.84 E-value: 4.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 782 DTKPELNVASSEGGEMERRDSDSFLNI-FPEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPS-PEEGTS 859
Cdd:COG5180 64 DIKLALGKPQLPSVAEPEAYLDPAPPKsSPDTPEEQLGAPAGDLLVLPAAKTPELAAGALPAPAAAAALPKAKvTREATS 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 860 IAAVPAPEGTAV--------------VAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGT----- 920
Cdd:COG5180 144 ASAGVALAAALLqrsdpilakdpdgdSASTLPPPAEKLDKVLTEPRDALKDSPEKLDRPKVEVKDEAQEEPPDLTggadh 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 921 AAVAAVSSPEETAPAVAAAITQEGMSAVAG-FSPEWAALAITVPITEEDGTPEGPVTPATTvhAPEEPDTAAVRVSTPE- 998
Cdd:COG5180 224 PRPEAASSPKVDPPSTSEARSRPATVDAQPeMRPPADAKERRRAAIGDTPAAEPPGLPVLE--AGSEPQSDAPEAETARp 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 999 ---EPASPAAAVPTPEEPT--SPAAAVPTPEEPTSPAAAVPPPEEPTSP---AAAVPTPEEPTSPAA----------AVP 1060
Cdd:COG5180 302 idvKGVASAPPATRPVRPPggARDPGTPRPGQPTERPAGVPEAASDAGQppsAYPPAEEAVPGKPLEqgaprpgssgGDG 381
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1061 TPEEPTS--PAAAVPTPEEPTSPAAAVPTPEEPT-------------------------SPAAAVP---------TPEEP 1104
Cdd:COG5180 382 APFQPPNgaPQPGLGRRGAPGPPMGAGDLVQAALdgggretaslggaaggagqgpkadfVPGDAESvsgpagladQAGAA 461
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1105 TSPAAAVP-TPEEPASPAAAVPTPEepASPAAAVPTPEEPAFPAPAVptpeesASAAVAVPTPEESASPAAAVPTPAESA 1183
Cdd:COG5180 462 ASTAMADFvAPVTDATPVDVADVLG--VRPDAILGGNVAPASGLDAE------TRIIEAEGAPATEDFVAAELSELREAA 533
|
.
gi 2245149928 1184 S 1184
Cdd:COG5180 534 E 534
|
|
| PRK13108 |
PRK13108 |
prolipoprotein diacylglyceryl transferase; Reviewed |
1115-1307 |
4.64e-07 |
|
prolipoprotein diacylglyceryl transferase; Reviewed
Pssm-ID: 237284 [Multi-domain] Cd Length: 460 Bit Score: 55.37 E-value: 4.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1115 EEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPtPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEE 1194
Cdd:PRK13108 280 EAPGALRGSEYVVDEALEREPAELAAAAVASAASAVG-PVGPGEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADRDGE 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1195 PTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAavsnPEEPTSPAAAVPTLEEPTSSaaavltpeELSSPAASV 1274
Cdd:PRK13108 359 STPAVEETSEADIEREQPGDLAGQAPAAHQVDAEAASAA----PEEPAALASEAHDETEPEVP--------EKAAPIPDP 426
|
170 180 190
....*....|....*....|....*....|...
gi 2245149928 1275 PTPEEPASPAAAVSnleePASPAAAVPTPEVAA 1307
Cdd:PRK13108 427 AKPDELAVAGPGDD----PAEPDGIRRQDDFSS 455
|
|
| DUF3729 |
pfam12526 |
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ... |
1014-1101 |
4.67e-07 |
|
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.
Pssm-ID: 372164 [Multi-domain] Cd Length: 115 Bit Score: 50.85 E-value: 4.67e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1014 TSPAAAVPTPEEPTSPAAAvPPPEEPTSPAAAVPTPEEPTSPAAavPTPEEPTSPAAAVPTPEEPTSPaaavPTPEEPTS 1093
Cdd:pfam12526 22 TSGFSSCFSPPESAHPDPP-PPVGDPRPPVVDTPPPVSAVWVLP--PPSEPAAPEPDLVPPVTGPAGP----PSPLAPPA 94
|
....*...
gi 2245149928 1094 PAAAVPTP 1101
Cdd:pfam12526 95 PAQKPPLP 102
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
2908-3001 |
5.00e-07 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 50.78 E-value: 5.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2908 LLEWLSEAEQTLRfRGALPDDTEALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDcITTIKHWITIIRARFE 2987
Cdd:pfam00435 13 LESWIEEKEALLS-SEDYGKDLESVQALLKKHKALEAELAAHQDRVEALNELAEKLIDEGHYA-SEEIQERLEELNERWE 90
|
90
....*....|....
gi 2245149928 2988 EVLTWAKQHQQRLE 3001
Cdd:pfam00435 91 QLLELAAERKQKLE 104
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
890-1051 |
5.18e-07 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 54.77 E-value: 5.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 890 SLEEEDVTAAAVSAPERAT-VPAVTVSVPEGTAAVAAVSSPEETAPAvAAAITQEGMSAVAGFSPEWAALAITVPITEED 968
Cdd:NF040712 176 TVTALDDEARWLIDPDFGRpLRPLATVPRLAREPADARPEEVEPAPA-AEGAPATDSDPAEAGTPDDLASARRRRAGVEQ 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 969 GTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAA-AVPTPEEPTSPAAAVPPPEEPTSPAAAVP 1047
Cdd:NF040712 255 PEDEPVGPGAAPAAEPDEATRDAGEPPAPGAAETPEAAEPPAPAPAAPAApAAPEAEEPARPEPPPAPKPKRRRRRASVP 334
|
....
gi 2245149928 1048 TPEE 1051
Cdd:NF040712 335 SWDD 338
|
|
| PRK13108 |
PRK13108 |
prolipoprotein diacylglyceryl transferase; Reviewed |
1128-1317 |
5.85e-07 |
|
prolipoprotein diacylglyceryl transferase; Reviewed
Pssm-ID: 237284 [Multi-domain] Cd Length: 460 Bit Score: 55.37 E-value: 5.85e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1128 EEPASPAAAVPTPEEPAFPAPAvptpeesASAAVAVPTPEESASPAAavptPAESASFAAVVATLEEPTSPAASVPTPAA 1207
Cdd:PRK13108 280 EAPGALRGSEYVVDEALEREPA-------ELAAAAVASAASAVGPVG----PGEPNQPDDVAEAVKAEVAEVTDEVAAES 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1208 MVATLEEFTSPAASVPTSEEPASLAAAvsnPEEPTSPAAAVPTLEEPTSSAAavltpeelsspaasvptPEEPASPAAAV 1287
Cdd:PRK13108 349 VVQVADRDGESTPAVEETSEADIEREQ---PGDLAGQAPAAHQVDAEAASAA-----------------PEEPAALASEA 408
|
170 180 190
....*....|....*....|....*....|....*..
gi 2245149928 1288 SNLEEPASPAAAVPTPE-------VAAIPAASVPTPE 1317
Cdd:PRK13108 409 HDETEPEVPEKAAPIPDpakpdelAVAGPGDDPAEPD 445
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
1090-1162 |
6.19e-07 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 55.78 E-value: 6.19e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1090 EPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVA 1162
Cdd:COG5373 36 ELAEAAEAASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEAEPAAAPAAASSFE 108
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
994-1317 |
6.35e-07 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 55.16 E-value: 6.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 994 VSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVP-TPEEPTSPAAAVPTPEEPTSPAAAV 1072
Cdd:NF033839 140 VSKFEKDSSSSSSSGSSTKPETPQPENPEHQKPTTPAPDTKPSPQPEGKKPSVPdINQEKEKAKLAVATYMSKILDDIQK 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1073 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVP----------TPEEPASPAAAVPTPE- 1141
Cdd:NF033839 220 HHLQKEKHRQIVALIKELDELKKQALSEIDNVNTKVEIENTVHKIFADMDAVVtkfkkgltqdTPKEPGNKKPSAPKPGm 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1142 --EPAFPAPAVPTPEESASAAV--AVPTPEESASPAAAVPTPaesasfaAVVATLEEP---TSPAASVPTPAAMvatlEE 1214
Cdd:NF033839 300 qpSPQPEKKEVKPEPETPKPEVkpQLEKPKPEVKPQPEKPKP-------EVKPQLETPkpeVKPQPEKPKPEVK----PQ 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1215 FTSPAASVPTseEPASLAAAVSnpEEPTSPAAAV-PTLEEPTSSAAAVL-TPEELSSPAASVPTPE---EPASPAAAVSn 1289
Cdd:NF033839 369 PEKPKPEVKP--QPETPKPEVK--PQPEKPKPEVkPQPEKPKPEVKPQPeKPKPEVKPQPEKPKPEvkpQPEKPKPEVK- 443
|
330 340 350
....*....|....*....|....*....|..
gi 2245149928 1290 lEEPASPAAAVP----TPEVAAIPAASVPTPE 1317
Cdd:NF033839 444 -PQPEKPKPEVKpqpeTPKPEVKPQPEKPKPE 474
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
2131-2237 |
6.44e-07 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 50.39 E-value: 6.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2131 ELAEKFWYDMAALLTTIKDTQDIVHDlESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFAcGETEKPEV 2210
Cdd:pfam00435 1 LLLQQFFRDADDLESWIEEKEALLSS-EDYGKDLESVQALLKKHKALEAELAAHQDRVEALNELAEKLIDE-GHYASEEI 78
|
90 100
....*....|....*....|....*..
gi 2245149928 2211 RKSIDEMNNAWENLNKTWKERLEKLED 2237
Cdd:pfam00435 79 QERLEELNERWEQLLELAAERKQKLEE 105
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
971-1218 |
6.81e-07 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 55.64 E-value: 6.81e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 971 PEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPT----PEEPTSPAAAVPTPE--EPTSPAAAVPPPEEPTSPAA 1044
Cdd:PLN03237 1202 PKKPAPKKTTKKASESETTEETYGSSAMETENVAEVVKPkgraGAKKKAPAAAKEKEEedEILDLKDRLAAYNLDSAPAQ 1281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1045 AVPTPEepTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT---------SPAAAVPTPEEPtsPAAAVPTPE 1115
Cdd:PLN03237 1282 SAKMEE--TVKAVPARRAAARKKPLASVSVISDSDDDDDDFAVEVSLAerlkkkggrKPAAANKKAAKP--PAAAKKRGP 1357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1116 EPASPAAAVPTPEEPASPAAAVPtPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVAtleeP 1195
Cdd:PLN03237 1358 ATVQSGQKLLTEMLKPAEAIGIS-PEKKVRKMRASPFNKKSGSVLGRAATNKETESSENVSGSSSSEKDEIDVSA----K 1432
|
250 260
....*....|....*....|...
gi 2245149928 1196 TSPAASVPTPAAMVATLEEFTSP 1218
Cdd:PLN03237 1433 PRPQRANRKQTTYVLSDSESESA 1455
|
|
| PRK14949 |
PRK14949 |
DNA polymerase III subunits gamma and tau; Provisional |
996-1366 |
7.20e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237863 [Multi-domain] Cd Length: 944 Bit Score: 55.50 E-value: 7.20e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 996 TPEEP------ASPAA-AVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAaavptpeEPTSPAAAVPTPEEPTsP 1068
Cdd:PRK14949 358 VPEKPvkrwqvDDPAEiSLPEGQTPSALAAAVQAPHANEPQFVNAAPAEKKTALT-------EQTTAQQQVQAANAEA-V 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1069 AAAVPTPEeptSPAAAVPTPEEPTSPAAAV-----------------PTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPA 1131
Cdd:PRK14949 430 AEADASAE---PADTVEQALDDESELLAALnaeqavilsqaqsqgfeASSSLDADNSAVPEQIDSTAEQSVVNPSVTDTQ 506
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1132 SPAAAVPTPEEPAFPAPAVPTPEESASAAVAVP-------TPEESASPAAAVPTPAESASFAAVVATLEEPTSPAAS-VP 1203
Cdd:PRK14949 507 VDDTSASNNSAADNTVDDNYSAEDTLESNGLDEgdyaqdsAPLDAYQDDYVAFSSESYNALSDDEQHSANVQSAQSAaEA 586
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1204 TPAAMVATLEEFTSPAASVPTSEE--PASLAAAVS--------NPEE-----------PTSPAAAVPTLEEP--TSSAAA 1260
Cdd:PRK14949 587 QPSSQSLSPISAVTTAAASLADDDilDAVLAARDSllsdldalSPKEgdgkkssadrkPKTPPSRAPPASLSkpASSPDA 666
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1261 VLTPEELSSPAASVPTPEEPASPAAAVSNL----------------EEPASPAAAVPTPEVAAIPAASVP------TPEV 1318
Cdd:PRK14949 667 SQTSASFDLDPDFELATHQSVPEAALASGSapapppvpdpydrppwEEAPEVASANDGPNNAAEGNLSESvedasnSELQ 746
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 2245149928 1319 PAIPAAAVPPMEEVSPIGVPFLGVSAHTDS-VPISEEGTPVLEEASSTG 1366
Cdd:PRK14949 747 AVEQQATHQPQVQAEAQSPASTTALTQTSSeVQDTELNLVLLSSGSITG 795
|
|
| PHA03321 |
PHA03321 |
tegument protein VP11/12; Provisional |
1020-1290 |
7.38e-07 |
|
tegument protein VP11/12; Provisional
Pssm-ID: 223041 [Multi-domain] Cd Length: 694 Bit Score: 55.35 E-value: 7.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1020 VPTP--EEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPeeptSPAAA 1097
Cdd:PHA03321 413 VPSEhyEASLRLLSSRQPPGAPAPRRDNDPPPPPRARPGSTPACARRARAQRARDAGPEYVDPLGALRRLP----AGAAP 488
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1098 VPTPEEPTSPAA-----AVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPA-VPTPEESASAAVAVPTPEESAS 1171
Cdd:PHA03321 489 PPEPAAAPSPATyytrmGGGPPRLPPRNRATETLRPDWGPPAAAPPEQMEDPYLEPDdDRFDRRDGAAAAATSHPREAPA 568
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1172 PaaavptpaESASFAAVVATLEEPTSpaASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNP-----EEPT-SPA 1245
Cdd:PHA03321 569 P--------DDDPIYEGVSDSEEPVY--EEIPTPRVYQNPLPRPMEGAGEPPDLDAPTSPWVEEENPiygwgDSPLfSPP 638
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 2245149928 1246 AAvpTLEEPTSSAAAVLTPE-ELSSPAASVPTPEEPASPAAAVSNL 1290
Cdd:PHA03321 639 PA--ARFPPPDPALSPEPPAlPAHRPRPGALAPDGPANLAALSAML 682
|
|
| PRK12727 |
PRK12727 |
flagellar biosynthesis protein FlhF; |
843-1050 |
7.64e-07 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 237182 [Multi-domain] Cd Length: 559 Bit Score: 55.00 E-value: 7.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 843 VKDALDAALPSPEeGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEE----DVTAAAVSAPERATVPAVTVSVPE 918
Cdd:PRK12727 51 VQRALETARSDTP-ATAAAPAPAPQAPTKPAAPVHAPLKLSANANMSQRQRVasaaEDMIAAMALRQPVSVPRQAPAAAP 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 919 GTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFsPE--WAALAITVPITEedgtpegPVTPATTVHAPEEPDTAAVRVST 996
Cdd:PRK12727 130 VRAASIPSPAAQALAHAAAVRTAPRQEHALSAV-PEqlFADFLTTAPVPR-------APVQAPVVAAPAPVPAIAAALAA 201
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 997 PEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPE 1050
Cdd:PRK12727 202 HAAYAQDDDEQLDDDGFDLDDALPQILPPAALPPIVVAPAAPAALAAVAAAAPA 255
|
|
| DUF3729 |
pfam12526 |
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ... |
1066-1153 |
7.88e-07 |
|
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.
Pssm-ID: 372164 [Multi-domain] Cd Length: 115 Bit Score: 50.46 E-value: 7.88e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1066 TSPAAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPTPEEPTSPAAavPTPEEPASPAAAVPTPEEPASPaaavPTPEEPAF 1145
Cdd:pfam12526 22 TSGFSSCFSPPESAHPDPP-PPVGDPRPPVVDTPPPVSAVWVLP--PPSEPAAPEPDLVPPVTGPAGP----PSPLAPPA 94
|
....*...
gi 2245149928 1146 PAPAVPTP 1153
Cdd:pfam12526 95 PAQKPPLP 102
|
|
| SAV_2336_NTERM |
NF041121 |
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ... |
1066-1148 |
8.12e-07 |
|
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.
Pssm-ID: 469044 [Multi-domain] Cd Length: 473 Bit Score: 54.62 E-value: 8.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1066 TSPAAAVPTPEEPTSPAAAVP-TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAA----VPTP 1140
Cdd:NF041121 15 MGRAAAPPSPEGPAPTAASQPaTPPPPAAPPSPPGDPPEPPAPEPAPLPAPYPGSLAPPPPPPPGPAGAAPGaalpVRVP 94
|
....*...
gi 2245149928 1141 EEPAFPAP 1148
Cdd:NF041121 95 APPALPNP 102
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
1015-1146 |
8.66e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 55.07 E-value: 8.66e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1015 SPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEptSPAAAVPTPEEPTSPaaavPTPEEPTSP 1094
Cdd:PRK14959 379 SAPSGSAAEGPASGGAATIPTPGTQGPQGTAPAAGMTPSSAAPATPAPSA--APSPRVPWDDAPPAP----PRSGIPPRP 452
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1095 AAAVPtpeeptspaAAVPTPEEPASPAAAVPTPeePASPAAAVPTPEEPAFP 1146
Cdd:PRK14959 453 APRMP---------EASPVPGAPDSVASASDAP--PTLGDPSDTAEHTPSGP 493
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
897-1313 |
9.74e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 55.18 E-value: 9.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 897 TAAAVSAPERATVPAVTVSVPEGTAAVAAvSSPEETAPAVAAAITQ---------EGMSAVAGFS-------PEWAALAI 960
Cdd:PHA03307 606 NAADTGAGAAAPAPAAPRPDAAAAGGASA-RPLRELADACVLACRAvleallegpDGLSAVPGLAfprpacpPRALEACP 684
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 961 TVPITE-------EDGTPEGPVTPATTVHAPEEPDTAAVR-VSTPEEPASPAAAVpTPEEPTSPAAAVPTPEEPTSPAAA 1032
Cdd:PHA03307 685 ARLESWlrelrdlRDAVYLARLRGDLPVAGGREERVAAVRaVSLVARTVAPLVRY-SPRRARARASAWDITDALFSNPSL 763
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1033 VPPPeepTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV-PTPEEPTSPAAAVPTPE--EPTSPAAAVPTPEEPTSPAA 1109
Cdd:PHA03307 764 VPAK---LAEALALLEPAEPQRGAGSSPPVRAEAAFRRPGrLRRSGPAADAASRTASKrkSRSHTPDGGSESSGPARPPG 840
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1110 AVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPeesasPAAAVPTPAESASFAAVV 1189
Cdd:PHA03307 841 AAARPPPARSSESSKSKPAAAGGRARGKNGRRRPRPPEPRARPGAAAPPKAAAAAPP-----AGAPAPRPRPAPRVKLGP 915
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1190 ATLEEPTS-------PAASVPTPAAMVATLEEFTSPAASVPTSEE--------------PASLA--AAVSNPEEPTS--- 1243
Cdd:PHA03307 916 MPPGGPDPrggfrrvPPGDLHTPAPSAAALAAYCPPEVVAELVDHplfpepwrpalafdPEALAeiAARCGGPPPRSgsa 995
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1244 --PAAAVPTL----------EEPTSSAAAVL-TP---EELSSPAASVPTPEEPA-SPA--------AAVSN-LEEPASPA 1297
Cdd:PHA03307 996 fgPLRASGPLrrraawmrqiPDPEDVRVVVLySPlpgEHLFGVPAPDASPGGPAwSPErgglsfllAALGNrLCLPDSHA 1075
|
490
....*....|....*....
gi 2245149928 1298 AA---VPTPEVAAIPAASV 1313
Cdd:PHA03307 1076 WAgnwTGAPDVSALNAQGV 1094
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1450-2056 |
9.74e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.94 E-value: 9.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1450 ARWNTLNKKVAQRIAQLQEAllhcgkfQDALEPLLSWLADTEELIANQKppsAEYKVVKAQIQEQKLLQRLLDDRKAtvd 1529
Cdd:COG1196 232 LKLRELEAELEELEAELEEL-------EAELEELEAELAELEAELEELR---LELEELELELEEAQAEEYELLAELA--- 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1530 mlQAEGGRIAQSAELADREKITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEpisDFLSVTEKKLANSEpv 1609
Cdd:COG1196 299 --RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE---AELAEAEEALLEAE-- 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1610 gTQTAKIQQQIIRHKALNEEIVNRKKNVDQAIKNGQALLKQTTGEEVLLIQEKLdgiktryaditvtsSKALRTLEQARQ 1689
Cdd:COG1196 372 -AELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELE--------------ELEEALAELEEE 436
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1690 LATKFQSTYEELTGWLREVEEELATSGGQSPTGEQIPQFQQRQKELKKEVMEHRLVLDTVNEVSR-ALLELVPWRAREGL 1768
Cdd:COG1196 437 EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAdYEGFLEGVKAALLL 516
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1769 DKLVSDANEQYKLVSDTIGQRVDEIDAAIQRSQQY----EQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAF 1844
Cdd:COG1196 517 AGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIvvedDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGA 596
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1845 SIDIIRHKDSMDELFSHRSEIFGtcgeeqktvlqektesliqqyeAISLLNSERYARLERAQVLVNQFWETYEelspwiE 1924
Cdd:COG1196 597 IGAAVDLVASDLREADARYYVLG----------------------DTLLGRTLVAARLEAALRRAVTLAGRLR------E 648
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1925 ETRALIAQLPSPAIDHEQLRQQQEEMRQLRESIAEhkphidkllkigpQLKELNPEEGEMVEEKYQKAENMYAQIKEEVR 2004
Cdd:COG1196 649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEE-------------LAERLAEEELELEEALLAEEEEERELAEAEEE 715
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 2005 QRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRMPPLIPAEVDKIRE 2056
Cdd:COG1196 716 RLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767
|
|
| PTZ00436 |
PTZ00436 |
60S ribosomal protein L19-like protein; Provisional |
1147-1315 |
1.00e-06 |
|
60S ribosomal protein L19-like protein; Provisional
Pssm-ID: 185616 [Multi-domain] Cd Length: 357 Bit Score: 54.19 E-value: 1.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1147 APAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAmvatleeftspAASVPTSE 1226
Cdd:PTZ00436 194 AAAAAAKQKAAAKKAAAPSGKKSAKAAAPAKAAAAPAKAAAPPAKAAAAPAKAAAAPAKAA-----------APPAKAAA 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1227 EPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSnleepASPAAAVPTPEVA 1306
Cdd:PTZ00436 263 PPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAAPAKAAAAPAKAAAAPAKAAAPPAKAA-----APPAKAATPPAKA 337
|
....*....
gi 2245149928 1307 AIPAASVPT 1315
Cdd:PTZ00436 338 AAPPAKAAA 346
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
950-1090 |
1.00e-06 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 54.00 E-value: 1.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 950 GFSPEWAALAITVPITEEDGTPEGPVTPATTVHaPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSP 1029
Cdd:NF040712 200 ATVPRLAREPADARPEEVEPAPAAEGAPATDSD-PAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPDEATRDAG 278
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1030 AAAVP-PPEEPTSPAAAVPTPEEPTSPAAavPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090
Cdd:NF040712 279 EPPAPgAAETPEAAEPPAPAPAAPAAPAA--PEAEEPARPEPPPAPKPKRRRRRASVPSWDD 338
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
1006-1099 |
1.06e-06 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 53.88 E-value: 1.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1006 AVPTPEEPTSPAAAVPTPeeptSPAAAVPPPEEPTSPAAAVPTPE-EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1084
Cdd:PRK10856 161 SVPLDTSTTTDPATTPAP----AAPVDTTPTNSQTPAVATAPAPAvDPQQNAVVAPSQANVDTAATPAPAAPATPDGAAP 236
|
90
....*....|....*
gi 2245149928 1085 VPTPEEPTSPAAAVP 1099
Cdd:PRK10856 237 LPTDQAGVSTPAADP 251
|
|
| PRK12727 |
PRK12727 |
flagellar biosynthesis protein FlhF; |
867-1102 |
1.15e-06 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 237182 [Multi-domain] Cd Length: 559 Bit Score: 54.61 E-value: 1.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 867 EGTAVVAALvpfPHEDILVASIVSLEEEDVTAAAVS---APERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAItqe 943
Cdd:PRK12727 36 EGIEIVAAS---NYDEELVQRALETARSDTPATAAApapAPQAPTKPAAPVHAPLKLSANANMSQRQRVASAAEDMI--- 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 944 gmsavagfspewAALAITVPITEEDGTPEG-PVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAvPT 1022
Cdd:PRK12727 110 ------------AAMALRQPVSVPRQAPAAaPVRAASIPSPAAQALAHAAAVRTAPRQEHALSAVPEQLFADFLTTA-PV 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1023 PEEPTSPAAAVPPPEEPTSPAAaVPTPEEPTSPAAAVPTP-----EEPTSPaaAVPTPEEPTSpAAAVPTPEEPTSPAAA 1097
Cdd:PRK12727 177 PRAPVQAPVVAAPAPVPAIAAA-LAAHAAYAQDDDEQLDDdgfdlDDALPQ--ILPPAALPPI-VVAPAAPAALAAVAAA 252
|
....*
gi 2245149928 1098 VPTPE 1102
Cdd:PRK12727 253 APAPQ 257
|
|
| KLF14_N |
cd21576 |
N-terminal domain of Kruppel-like factor 14; Kruppel-like factor 14 (KLF14; also known as ... |
1151-1310 |
1.17e-06 |
|
N-terminal domain of Kruppel-like factor 14; Kruppel-like factor 14 (KLF14; also known as Krueppel-like factor 14 or basic transcription element-binding protein 5/BTEB5) is a protein that in humans is encoded by the KLF14 gene. KLF14 regulates the transcription of various genes, including TGFbetaRII (the type II receptor for TGFbeta). KLF14 is expressed in many tissues, lacks introns, and is subject to parent-specific expression. It also appears to be a master regulator of gene expression in adipose tissue. KLF14 is associated with coronary artery disease, hypercholesterolemia, and type 2 diabetes. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. KLF14 belongs to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the N-terminal domain of KLF14.
Pssm-ID: 409238 [Multi-domain] Cd Length: 195 Bit Score: 51.74 E-value: 1.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1151 PTPEESASAAVAV--PTPEESASPAAAVPTPAesasfaAVVATLEEPT-SPAASVPTPAAMVATLEEFTSPAASVPTSEE 1227
Cdd:cd21576 29 PDPEGAGGAAGSEvgAAPPESALPGPGPPGPA------WVPPLLQVPApSPGAGGAAPHLLAASVLADLRGGAGEGSRED 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1228 PASLAAAVSNPEEPTSPAAAVPTLEE-PTSSAAAVLTPEElSSPAASVP-TPEEPASPAAAVsnlEEPASPAAAVPTPev 1305
Cdd:cd21576 103 SGEAPRASSGSSDPARGSSPTLGSEPaPASGEDAVSGPES-SFGAPAIPsAPAAPGAPAVSG---EVPGGAPGAGPAP-- 176
|
....*
gi 2245149928 1306 AAIPA 1310
Cdd:cd21576 177 AAGPA 181
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
1045-1138 |
1.18e-06 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 53.49 E-value: 1.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1045 AVPTPEEPTSPAAAVPTPEEPTsPAAAVPTPEEPTSPAAAVPTPeePTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAV 1124
Cdd:PRK10856 161 SVPLDTSTTTDPATTPAPAAPV-DTTPTNSQTPAVATAPAPAVD--PQQNAVVAPSQANVDTAATPAPAAPATPDGAAPL 237
|
90
....*....|....
gi 2245149928 1125 PTPEEPASPAAAVP 1138
Cdd:PRK10856 238 PTDQAGVSTPAADP 251
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
988-1073 |
1.19e-06 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 53.49 E-value: 1.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 988 DTAAVRVSTPEEPASPAAAVPTPeEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAA-AVPTPEEPTSPAAAVPTPEEPT 1066
Cdd:PRK10856 166 TSTTTDPATTPAPAAPVDTTPTN-SQTPAVATAPAPAVDPQQNAVVAPSQANVDTAAtPAPAAPATPDGAAPLPTDQAGV 244
|
....*..
gi 2245149928 1067 SPAAAVP 1073
Cdd:PRK10856 245 STPAADP 251
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
1077-1148 |
1.26e-06 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 54.62 E-value: 1.26e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1077 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPtPEEPAFPAP 1148
Cdd:COG5373 36 ELAEAAEAASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEAEP-AAAPAAASS 106
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
994-1143 |
1.31e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 54.20 E-value: 1.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 994 VSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTP----------- 1062
Cdd:PRK14948 368 IANASAPANPTPAPNPSPPPAPIQPSAPKTKQAATTPSPPPAKASPPIPVPAEPTEPSPTPPANAANAPpslnleelwqq 447
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1063 -----EEPT-------------------------------------------------------------SPAAAVPTPE 1076
Cdd:PRK14948 448 ilaklELPStrmllsqqaelvsldsnraviavspnwlgmvqsrkplleqafakvlgrsiklnlesqsgsaSNTAKTPPPP 527
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1077 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEP 1143
Cdd:PRK14948 528 QKSPPPPAPTPPLPQPTATAPPPTPPPPPPTATQASSNAPAQIPADSSPPPPIPEEPTPSPTKDSSP 594
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
1064-1136 |
1.31e-06 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 54.62 E-value: 1.31e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1064 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPtpeePASPAAA 1136
Cdd:COG5373 36 ELAEAAEAASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEAEP----AAAPAAA 104
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
1871-2121 |
1.37e-06 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 54.07 E-value: 1.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1871 EEQKTVLQEKTESLIQQYEAisllNSERYARLE------RAQVLVN--QFWETYEELSPWIEETRALIAQL--------P 1934
Cdd:PRK04778 118 EEDIEQILEELQELLESEEK----NREEVEQLKdlyrelRKSLLANrfSFGPALDELEKQLENLEEEFSQFveltesgdY 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1935 SPAidHEQLRQQQEEMRQLRESIAEHKPHIDKLLKIGP-QLKELnpEEG--EMVEEKY----QKAENMYAQIKEEVRQ-- 2005
Cdd:PRK04778 194 VEA--REILDQLEEELAALEQIMEEIPELLKELQTELPdQLQEL--KAGyrELVEEGYhldhLDIEKEIQDLKEQIDEnl 269
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2006 ---RALALDEAvsqSTQITEFHDKIEPMLETLEN-LSSR----LRMPPlIPAEVDKIREcisDNKSATVELEKLQPSFE- 2076
Cdd:PRK04778 270 allEELDLDEA---EEKNEEIQERIDQLYDILEReVKARkyveKNSDT-LPDFLEHAKE---QNKELKEEIDRVKQSYTl 342
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 2077 ---------ALKRRGEELIGRSQGADKDLAAK-----EIQDKLDQMVFFWEDIKARAEE 2121
Cdd:PRK04778 343 neselesvrQLEKQLESLEKQYDEITERIAEQeiaysELQEELEEILKQLEEIEKEQEK 401
|
|
| PHA03269 |
PHA03269 |
envelope glycoprotein C; Provisional |
956-1092 |
1.46e-06 |
|
envelope glycoprotein C; Provisional
Pssm-ID: 165527 [Multi-domain] Cd Length: 566 Bit Score: 53.96 E-value: 1.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 956 AALAITVPITE---EDGTPEGPVTPATTVHAPEEPDTAAVrvstpeePASPAAAVPTPEEPTSPAAAV---PTPeEPTSP 1029
Cdd:PHA03269 20 ANLNTNIPIPElhtSAATQKPDPAPAPHQAASRAPDPAVA-------PTSAASRKPDLAQAPTPAASEkfdPAP-APHQA 91
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1030 AAAVP-PPEEPTSPAAAVPTPEEP-TSPAAAVPTP-EEPTSPAAAVPTpeeptsPAAAVPTPEEPT 1092
Cdd:PHA03269 92 ASRAPdPAVAPQLAAAPKPDAAEAfTSAAQAHEAPaDAGTSAASKKPD------PAAHTQHSPPPF 151
|
|
| KREPA2 |
cd23959 |
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of ... |
964-1143 |
1.49e-06 |
|
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of the parasitic protozoan's KREPA RNA editing catalytic complex (RECC). Kinetoplastid RNA editing (KRE) proteins occur as pairs or sets of related proteins in multiple complexes. KREPA complex is composed of six components (KREPA1-6), which share a conserved C-terminal region containing an oligonucleotide-binding (OB)-fold-like domain. KREPAs are responsible for the site-specific insertion and deletion of U nucleotides in the kinetoplastid mitochondria pre-messenger RNA. Apart from the conserved C-terminal OB-fold domain, KREPA1, KREPA2, and KREPA3 contain two conserved C2H2 zinc-finger domains. KREPA2 and kinetoplastid RNA editing ligase 1 (KREL1) are specific for ligation post-U-deletion and are paralogous to KREL2 and KREPA1 that are specific for ligation post-U-insertion. KREPA2, is critical for RECC stability and KREL1 integration into the complex.
Pssm-ID: 467780 [Multi-domain] Cd Length: 424 Bit Score: 53.72 E-value: 1.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 964 ITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAaavptPEEPTSP--AAAVPTP-EEPTSPAAAVPPPEEPT 1040
Cdd:cd23959 62 SPEGENPFDGPGLVTASTVSDCYVGNANFYEVDMSDAFAMA-----PDESLGPfrAARVPNPfSASSSTQRETHKTAQVA 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1041 SPAAAVPTPeePTSPAAAVPT-----PEEPTSPAAAVPTPEepTSPAAAVPTP----EEPTSP-AAAVPTPEEPTSPAAA 1110
Cdd:cd23959 137 PPKAEPQTA--PVTPFGQLPMfgqhpPPAKPLPAAAAAQQS--SASPGEVASPfasgTVSASPfATATDTAPSSGAPDGF 212
|
170 180 190
....*....|....*....|....*....|...
gi 2245149928 1111 VPTPEEPaSPAAAVPTPEepASPAAAVPTPEEP 1143
Cdd:cd23959 213 PAEASAP-SPFAAPASAA--SFPAAPVANGEAA 242
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
1917-2012 |
1.55e-06 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 49.24 E-value: 1.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1917 EELSPWIEETRALIAQLPSPAiDHEQLRQQQEEMRQLRESIAEHKPHIDKLLKIGPQLKELNPEEGEMVEEKYQKAENMY 1996
Cdd:pfam00435 11 DDLESWIEEKEALLSSEDYGK-DLESVQALLKKHKALEAELAAHQDRVEALNELAEKLIDEGHYASEEIQERLEELNERW 89
|
90
....*....|....*.
gi 2245149928 1997 AQIKEEVRQRALALDE 2012
Cdd:pfam00435 90 EQLLELAAERKQKLEE 105
|
|
| SAV_2336_NTERM |
NF041121 |
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ... |
1002-1090 |
1.55e-06 |
|
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.
Pssm-ID: 469044 [Multi-domain] Cd Length: 473 Bit Score: 53.85 E-value: 1.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1002 SPAAAVPTPEEPTSPAAAVP-TPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPeePTS 1080
Cdd:NF041121 16 GRAAAPPSPEGPAPTAASQPaTPPPPAAPPSPPGDPPEPPAPEPAPLPAPYPGSLAPPPPPPPGPAGAAPGAALP--VRV 93
|
90
....*....|.
gi 2245149928 1081 PAAAV-PTPEE 1090
Cdd:NF041121 94 PAPPAlPNPLE 104
|
|
| SAV_2336_NTERM |
NF041121 |
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ... |
1027-1116 |
1.56e-06 |
|
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.
Pssm-ID: 469044 [Multi-domain] Cd Length: 473 Bit Score: 53.85 E-value: 1.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1027 TSPAAAVPPPEEPTSPAAAVP-TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPeePT 1105
Cdd:NF041121 15 MGRAAAPPSPEGPAPTAASQPaTPPPPAAPPSPPGDPPEPPAPEPAPLPAPYPGSLAPPPPPPPGPAGAAPGAALP--VR 92
|
90
....*....|..
gi 2245149928 1106 SPAAAV-PTPEE 1116
Cdd:NF041121 93 VPAPPAlPNPLE 104
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
956-1077 |
1.58e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 54.05 E-value: 1.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 956 AALAITVPITEEDGTPegpvTPATTVHAPEEPDTAAVRVSTPeePASPAAAVPTPEEPTSPAAAVPTPEeptspaaavPP 1035
Cdd:PRK14950 361 VPVPAPQPAKPTAAAP----SPVRPTPAPSTRPKAAAAANIP--PKEPVRETATPPPVPPRPVAPPVPH---------TP 425
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 2245149928 1036 PEEPTSPAAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPTPEE 1077
Cdd:PRK14950 426 ESAPKLTRAAIPVDEKPKYTPPA-PPKEEEKALIADGDVLEQ 466
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
1195-1357 |
1.63e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 54.09 E-value: 1.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1195 PTSPAASVPTPAAMVATleeftSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASV 1274
Cdd:PRK07003 373 PARVAGAVPAPGARAAA-----AVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDA 447
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1275 PTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEE 1354
Cdd:PRK07003 448 PVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAP 527
|
...
gi 2245149928 1355 GTP 1357
Cdd:PRK07003 528 PAP 530
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
1067-1182 |
1.67e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 53.92 E-value: 1.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1067 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAvptPEEPTSPAAAVP-TPEEPASPAAAVPTPEEPASPaaavPTPEEPAF 1145
Cdd:PRK14959 379 SAPSGSAAEGPASGGAATIPTPGTQGPQGTA---PAAGMTPSSAAPaTPAPSAAPSPRVPWDDAPPAP----PRSGIPPR 451
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 2245149928 1146 PAPAVP-------TPEESASAAVAVPTPEESASPAAAVPTPAES 1182
Cdd:PRK14959 452 PAPRMPeaspvpgAPDSVASASDAPPTLGDPSDTAEHTPSGPRT 495
|
|
| PTZ00436 |
PTZ00436 |
60S ribosomal protein L19-like protein; Provisional |
1121-1286 |
1.74e-06 |
|
60S ribosomal protein L19-like protein; Provisional
Pssm-ID: 185616 [Multi-domain] Cd Length: 357 Bit Score: 53.42 E-value: 1.74e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1121 AAAVPTPEEPASPAAAVPTPEEPAfpAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATleePTSPAA 1200
Cdd:PTZ00436 194 AAAAAAKQKAAAKKAAAPSGKKSA--KAAAPAKAAAAPAKAAAPPAKAAAAPAKAAAAPAKAAAPPAKAAA---PPAKAA 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1201 SVPTPAAMVATleefTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVP--TLEEPTSSAAAvltPEELSSPAASVPTPe 1278
Cdd:PTZ00436 269 APPAKAAAPPA----KAAAPPAKAAAPPAKAAAAPAKAAAAPAKAAAAPakAAAPPAKAAAP---PAKAATPPAKAAAP- 340
|
....*...
gi 2245149928 1279 ePASPAAA 1286
Cdd:PTZ00436 341 -PAKAAAA 347
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
1040-1125 |
1.84e-06 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 53.11 E-value: 1.84e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1040 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPAS 1119
Cdd:PRK10856 166 TSTTTDPATTPAPAAPVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPSQANVDTAATPAPAAPATPDGAAPLPTDQAGVS 245
|
....*.
gi 2245149928 1120 PAAAVP 1125
Cdd:PRK10856 246 TPAADP 251
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
1027-1112 |
1.90e-06 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 53.11 E-value: 1.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1027 TSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1106
Cdd:PRK10856 166 TSTTTDPATTPAPAAPVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPSQANVDTAATPAPAAPATPDGAAPLPTDQAGVS 245
|
....*.
gi 2245149928 1107 PAAAVP 1112
Cdd:PRK10856 246 TPAADP 251
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
1223-1338 |
1.94e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 53.95 E-value: 1.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1223 PTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPA--SPAAAVSNLEEPASPAAAV 1300
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPApvAAPAAAAPAAAPAAAPAAV 445
|
90 100 110
....*....|....*....|....*....|....*...
gi 2245149928 1301 PTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVP 1338
Cdd:PRK14951 446 ALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAP 483
|
|
| PRK10819 |
PRK10819 |
transport protein TonB; Provisional |
1021-1153 |
1.98e-06 |
|
transport protein TonB; Provisional
Pssm-ID: 236768 [Multi-domain] Cd Length: 246 Bit Score: 51.99 E-value: 1.98e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1021 PTPEEPTSPAAAVPPPEEPtspAAAVPTPEEPTspaaAVPTPEEPtspaaavPTPEEPTSPAAAVPTPEEPTSPaaaVPT 1100
Cdd:PRK10819 42 PAPAQPISVTMVAPADLEP---PQAVQPPPEPV----VEPEPEPE-------PIPEPPKEAPVVIPKPEPKPKP---KPK 104
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 2245149928 1101 PE-EPTSPAAAVPTPE-EPASPAAAvpTPEEPASPAAAVPTPEEPAFPAPAVPTP 1153
Cdd:PRK10819 105 PKpKPVKKVEEQPKREvKPVEPRPA--SPFENTAPARPTSSTATAAASKPVTSVS 157
|
|
| PRK11633 |
PRK11633 |
cell division protein DedD; Provisional |
1046-1161 |
2.00e-06 |
|
cell division protein DedD; Provisional
Pssm-ID: 236940 [Multi-domain] Cd Length: 226 Bit Score: 51.54 E-value: 2.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1046 VPTP---EEPTS-PAAAVPTPEEPTSPAAavptpEEPTSPAAAVPTPEEPTSPAaavptpeePTSPAAAVPTPEEPASPA 1121
Cdd:PRK11633 44 VPKPgdrDEPDMmPAATQALPTQPPEGAA-----EAVRAGDAAAPSLDPATVAP--------PNTPVEPEPAPVEPPKPK 110
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2245149928 1122 AAVPTPEEPASPAAAVPTPEepafPAPAVPTPEESASAAV 1161
Cdd:PRK11633 111 PVEKPKPKPKPQQKVEAPPA----PKPEPKPVVEEKAAPT 146
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
997-1364 |
2.03e-06 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 53.89 E-value: 2.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 997 PEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEP--------------TSPAAAVPTPEEPTSPAAAVPTP 1062
Cdd:PRK10811 524 PEQPALATFAMPDVPPAPTPAEPAAPVVAAAPKAAAATPPAQPgllsrffgalkalfSGGEETKPQEQPAPKAEAKPERQ 603
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1063 EE-------------------------------------------PTSPAAAVPTPEEPTSPAAAVPTPEEP-------- 1091
Cdd:PRK10811 604 QDrrkprqnnrrdrnerrdtrdnrtrregrenreenrrnrrqaqqQTAETRESQQAEVTEKARTQDEQQQAPrrerqrrr 683
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1092 ------TSPAAAVPTPEEPTSPAAAVPTPEEPASP--------------AAAVPTPEEPASPAAAVPTPEEPAFPAPAVP 1151
Cdd:PRK10811 684 ndekrqAQQEAKALNVEEQSVQETEQEERVQQVQPrrkqrqlnqkvrieQSVAEEAVAPVVEETVAAEPVVQEVPAPRTE 763
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1152 TPEESASAAVAVPTPEESASPAAA-----VP------------------------TPAESASFAAVVATLEEPTSPAASV 1202
Cdd:PRK10811 764 LVKVPLPVVAQTAPEQDEENNAENrdnngMPrrsrrsprhlrvsgqrrrryrderYPTQSPMPLTVACASPEMASGKVWI 843
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1203 PTPAAMV--ATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAvltpeelssPAASVPTPEEP 1280
Cdd:PRK10811 844 RYPVVRPqdVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAE---------PQPEEVVVVET 914
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1281 ASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEvPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLE 1360
Cdd:PRK10811 915 THPEVIAAPVTEQPQVITESDVAVAQEVAEHAEPVVE-PQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVET 993
|
....
gi 2245149928 1361 EASS 1364
Cdd:PRK10811 994 VTAV 997
|
|
| DUF3729 |
pfam12526 |
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ... |
1040-1127 |
2.41e-06 |
|
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.
Pssm-ID: 372164 [Multi-domain] Cd Length: 115 Bit Score: 48.92 E-value: 2.41e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1040 TSPAAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPTPEEPTSPAAavPTPEEPTSPAAAVPTPEEPTSPaaavPTPEEPAS 1119
Cdd:pfam12526 22 TSGFSSCFSPPESAHPDPP-PPVGDPRPPVVDTPPPVSAVWVLP--PPSEPAAPEPDLVPPVTGPAGP----PSPLAPPA 94
|
....*...
gi 2245149928 1120 PAAAVPTP 1127
Cdd:pfam12526 95 PAQKPPLP 102
|
|
| SAP130_C |
pfam16014 |
Histone deacetylase complex subunit SAP130 C-terminus; |
1032-1244 |
2.42e-06 |
|
Histone deacetylase complex subunit SAP130 C-terminus;
Pssm-ID: 464973 [Multi-domain] Cd Length: 371 Bit Score: 53.01 E-value: 2.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1032 AVPPPEEPTSPAAAVPTPEEPTspAAAVPTPEEPtspAAAVPTPEEPTSPaaavptPEEPTSPAAAVPtpeeptspaAAV 1111
Cdd:pfam16014 29 AVAPPVTVAVEALPGQNSEQQT--ASASPPSQHP---AQAIPTILAPAAP------PSQPSVVLSTLP---------AAM 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1112 P-TPEEPASPAAAVPTPEEPASPAAAVpTPEEPAFPAPAVPTPEESASAAVAVPTPeesaSPAAAVPTPAESASFAAVVA 1190
Cdd:pfam16014 89 AvTPPIPASMANVVAPPTQPAASSTAA-CAVSSVLPEIKIKQEAEPMDTSQSVPPL----TPTSISPALTSLANNLSVPA 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 1191 TLEEPTSPAASVPTPAAMVATLEEfTSPAASVPTSEEPASLAAAVSNPEEPTSP 1244
Cdd:pfam16014 164 GDLLPGASPRKKPRKQQHVISTEE-GEMMETNSTDEEKSAPKPLTSRAEKRKSP 216
|
|
| SAV_2336_NTERM |
NF041121 |
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ... |
1071-1168 |
2.52e-06 |
|
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.
Pssm-ID: 469044 [Multi-domain] Cd Length: 473 Bit Score: 53.08 E-value: 2.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1071 AVPTPEEPTSPAAAVPTPEEPTSPAaavpTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150
Cdd:NF041121 12 AAQMGRAAAPPSPEGPAPTAASQPA----TPPPPAAPPSPPGDPPEPPAPEPAPLPAPYPGSLAPPPPPPPGPAGAAPGA 87
|
90
....*....|....*...
gi 2245149928 1151 PTPeESASAAVAVPTPEE 1168
Cdd:NF041121 88 ALP-VRVPAPPALPNPLE 104
|
|
| PRK11633 |
PRK11633 |
cell division protein DedD; Provisional |
1007-1108 |
2.57e-06 |
|
cell division protein DedD; Provisional
Pssm-ID: 236940 [Multi-domain] Cd Length: 226 Bit Score: 51.54 E-value: 2.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1007 VPTP---EEPTS-PAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1082
Cdd:PRK11633 44 VPKPgdrDEPDMmPAATQALPTQPPEGAAEAVRAGDAAAPSLDPATVAPPNTPVEPEPAPVEPPKPKPVEKPKPKPKPQQ 123
|
90 100
....*....|....*....|....*.
gi 2245149928 1083 AAVPTPEEPTSPAaavPTPEEPTSPA 1108
Cdd:PRK11633 124 KVEAPPAPKPEPK---PVVEEKAAPT 146
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
1051-1123 |
2.61e-06 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 53.47 E-value: 2.61e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1051 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPtpeePASPAAA 1123
Cdd:COG5373 36 ELAEAAEAASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEAEP----AAAPAAA 104
|
|
| DUF3729 |
pfam12526 |
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ... |
1053-1140 |
2.73e-06 |
|
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.
Pssm-ID: 372164 [Multi-domain] Cd Length: 115 Bit Score: 48.92 E-value: 2.73e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1053 TSPAAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPTPEEPTSPAAavPTPEEPTSPAAAVPTPEEPASPaaavPTPEEPAS 1132
Cdd:pfam12526 22 TSGFSSCFSPPESAHPDPP-PPVGDPRPPVVDTPPPVSAVWVLP--PPSEPAAPEPDLVPPVTGPAGP----PSPLAPPA 94
|
....*...
gi 2245149928 1133 PAAAVPTP 1140
Cdd:pfam12526 95 PAQKPPLP 102
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
990-1239 |
2.89e-06 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 53.71 E-value: 2.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 990 AAVRVS--TPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPP----PEEPTSPAAAVPTPE--EPTSPAAAVPT 1061
Cdd:PLN03237 1193 AAKKVSrqAPKKPAPKKTTKKASESETTEETYGSSAMETENVAEVVKPkgraGAKKKAPAAAKEKEEedEILDLKDRLAA 1272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1062 PEEPTSPAAAVPTPEepTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPE 1141
Cdd:PLN03237 1273 YNLDSAPAQSAKMEE--TVKAVPARRAAARKKPLASVSVISDSDDDDDDFAVEVSLAERLKKKGGRKPAAANKKAAKPPA 1350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1142 EPAFPAPAVPTPEESASAAVAVPTPEESASP----AAAVPTPAESASfAAVVATLEEPTSPAASVPTPAAMVATLEEFTS 1217
Cdd:PLN03237 1351 AAKKRGPATVQSGQKLLTEMLKPAEAIGISPekkvRKMRASPFNKKS-GSVLGRAATNKETESSENVSGSSSSEKDEIDV 1429
|
250 260
....*....|....*....|..
gi 2245149928 1218 PAASVPTSEEPASLAAAVSNPE 1239
Cdd:PLN03237 1430 SAKPRPQRANRKQTTYVLSDSE 1451
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1446-2189 |
2.90e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.53 E-value: 2.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1446 EEINARWNTLNKKVAQRIAQLQEALLHCGKFQDalepLLSWLADTE--ELIANQKPPSAEYKVVKAQIQEqklLQRLLDD 1523
Cdd:TIGR02169 183 EENIERLDLIIDEKRQQLERLRREREKAERYQA----LLKEKREYEgyELLKEKEALERQKEAIERQLAS---LEEELEK 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1524 RKATVDMLQAEGGRIAQSAELADRE----------KITGQLESLESRWTELLSKAAARQKQLEDilvLAKQFHETAEPIS 1593
Cdd:TIGR02169 256 LTEEISELEKRLEEIEQLLEELNKKikdlgeeeqlRVKEKIGELEAEIASLERSIAEKERELED---AEERLAKLEAEID 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1594 DflsvTEKKLANSEpvgtqtAKIQQQIIRHKALNEEIVNRKKNVDQAIKNGQALLK--QTTGEEVLLIQEKLDGIKTRYA 1671
Cdd:TIGR02169 333 K----LLAEIEELE------REIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKefAETRDELKDYREKLEKLKREIN 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1672 DITVTSSKALRTLEQAR--------QLA------TKFQSTYEELTGWLREVEEELATSGGQ-SPTGEQIPQFQQRQKELK 1736
Cdd:TIGR02169 403 ELKRELDRLQEELQRLSeeladlnaAIAgieakiNELEEEKEDKALEIKKQEWKLEQLAADlSKYEQELYDLKEEYDRVE 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1737 KEVMEHRLVLDTVNEVSRALLELVPWRAR---------EGLDKLVSD---ANEQYKL-VSDTIGQRVDEI----DAAIQR 1799
Cdd:TIGR02169 483 KELSKLQRELAEAEAQARASEERVRGGRAveevlkasiQGVHGTVAQlgsVGERYATaIEVAAGNRLNNVvvedDAVAKE 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1800 SQQY---EQAADAELAWVAETKRKLMALGPIRLEQ------DQTTAQLQVQKAFSI---------DIIRHKDSMD----- 1856
Cdd:TIGR02169 563 AIELlkrRKAGRATFLPLNKMRDERRDLSILSEDGvigfavDLVEFDPKYEPAFKYvfgdtlvveDIEAARRLMGkyrmv 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1857 ----ELFSHRSEIFG-----TCGEEQKTVLQEKTESLIQQYEAISLLNSERYARLERAQVLVNQFWETYEELSPWIEETR 1927
Cdd:TIGR02169 643 tlegELFEKSGAMTGgsrapRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIE 722
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1928 ALIAQLpspAIDHEQLRQQQEEMR----QLRESIAEHKPHIDKL--------LKIGPQLKELNPEEGEMVEEKYQKAENM 1995
Cdd:TIGR02169 723 KEIEQL---EQEEEKLKERLEELEedlsSLEQEIENVKSELKELearieeleEDLHKLEEALNDLEARLSHSRIPEIQAE 799
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1996 YAQIKEEVRQ---RALALDEAVSQSTQITEF-HDKIEPMLETLENLSSRLRMpplIPAEVDKIRECISDNKSatvELEKL 2071
Cdd:TIGR02169 800 LSKLEEEVSRieaRLREIEQKLNRLTLEKEYlEKEIQELQEQRIDLKEQIKS---IEKEIENLNGKKEELEE---ELEEL 873
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2072 QPSFEALKRRGEELIGRSQGADKDLaaKEIQDKLDQMvffwedikarAEEREIKFLDVLELAEKfwydMAALLTTIKDTQ 2151
Cdd:TIGR02169 874 EAALRDLESRLGDLKKERDELEAQL--RELERKIEEL----------EAQIEKKRKRLSELKAK----LEALEEELSEIE 937
|
810 820 830
....*....|....*....|....*....|....*....
gi 2245149928 2152 D-IVHDLESPGIDPSIikqqveaaETIKEETDGLHEELE 2189
Cdd:TIGR02169 938 DpKGEDEEIPEEELSL--------EDVQAELQRVEEEIR 968
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
1172-1317 |
2.92e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 53.33 E-value: 2.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1172 PAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEfTSPAASVPTSEEPASLAAAV------SNPEEPTSPA 1245
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPP-ASAPQQAPAVPLPETTSQLLaarqqlQRAQGATKAK 439
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1246 AAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPE 1317
Cdd:PRK07994 440 KSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTPE 511
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
1116-1187 |
3.30e-06 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 53.08 E-value: 3.30e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 1116 EPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVP--TPAESASFAA 1187
Cdd:COG5373 36 ELAEAAEAASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEAEPaaAPAAASSFEE 109
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
999-1071 |
3.47e-06 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 53.08 E-value: 3.47e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 999 EPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEeptsPAAA 1071
Cdd:COG5373 36 ELAEAAEAASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEAEPAAA----PAAA 104
|
|
| DamX |
COG3266 |
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ... |
1018-1304 |
3.48e-06 |
|
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442497 [Multi-domain] Cd Length: 455 Bit Score: 52.54 E-value: 3.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1018 AAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT-SPAA 1096
Cdd:COG3266 73 ALASAALLLALASLALLGILLLALLALLLDLLLLADLLRAAALLLLKLLLLLLTLLLLVLLLLLALLLALLLDLPlLTLL 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1097 AVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAV 1176
Cdd:COG3266 153 IVLPLLEEQLLLLALQDIQGTLQALGAVAALLGLRKAEEALALRAGSAAADALALLLLLLASALGEAVAAAAELAALALL 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1177 PTPAESASFAAVVATL-------EEPTSPA-ASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPtSPAAAV 1248
Cdd:COG3266 233 AAGAAEVLTARLVLLLliigsalKAPSQASsASAPATTSLGEQQEVSLPPAVAAQPAAAAAAQPSAVALPAAP-AAAAAA 311
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1249 PTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAavsnleePASPAAAVPTPE 1304
Cdd:COG3266 312 AAPAEAAAPQPTAAKPVVTETAAPAAPAPEAAAAAAA-------PAAPAVAKKLAA 360
|
|
| PRK11633 |
PRK11633 |
cell division protein DedD; Provisional |
997-1095 |
3.52e-06 |
|
cell division protein DedD; Provisional
Pssm-ID: 236940 [Multi-domain] Cd Length: 226 Bit Score: 51.16 E-value: 3.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 997 PEEPASPAAAVPTPEEPtsPAAAVPTPEEPTSPAAAVPPP--EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1074
Cdd:PRK11633 51 DEPDMMPAATQALPTQP--PEGAAEAVRAGDAAAPSLDPAtvAPPNTPVEPEPAPVEPPKPKPVEKPKPKPKPQQKVEAP 128
|
90 100
....*....|....*....|.
gi 2245149928 1075 PEEPTSPAaavPTPEEPTSPA 1095
Cdd:PRK11633 129 PAPKPEPK---PVVEEKAAPT 146
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
1102-1317 |
3.78e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 52.66 E-value: 3.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1102 EEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAfPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAE 1181
Cdd:PRK14948 361 PSAFISEIANASAPANPTPAPNPSPPPAPIQPSAPKTKQAATT-PSPPPAKASPPIPVPAEPTEPSPTPPANAANAPPSL 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1182 SAS--FAAVVATLEEPTSpaasvptpaAMV----ATLEEFTSPAASVPTSE-------------EPAsLAAAVSNPEE-- 1240
Cdd:PRK14948 440 NLEelWQQILAKLELPST---------RMLlsqqAELVSLDSNRAVIAVSPnwlgmvqsrkpllEQA-FAKVLGRSIKln 509
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1241 ------PTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVP 1314
Cdd:PRK14948 510 lesqsgSASNTAKTPPPPQKSPPPPAPTPPLPQPTATAPPPTPPPPPPTATQASSNAPAQIPADSSPPPPIPEEPTPSPT 589
|
...
gi 2245149928 1315 TPE 1317
Cdd:PRK14948 590 KDS 592
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
1039-1160 |
3.85e-06 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 52.66 E-value: 3.85e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1039 PTSPAAAVPTPEEPTSPAAAVPTPEEPTsPAAAVPTPEEPTSPAAAVptpEEPTSPAAAVPTPEEPTSPAAAVPTPEEPA 1118
Cdd:PRK06995 53 PPAAAAPAAAQPPPAAAPAAVSRPAAPA-AEPAPWLVEHAKRLTAQR---EQLVARAAAPAAPEAQAPAAPAERAAAENA 128
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 2245149928 1119 SPAAAVPtpeePASPAAAVPTPEEPAFPAPAVPTPEESASAA 1160
Cdd:PRK06995 129 ARRLARA----AAAAPRPRVPADAAAAVADAVKARIERIVND 166
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
1157-1292 |
3.99e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 52.89 E-value: 3.99e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1157 ASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAamvatleeftspaasvPTSEEPASLAAAVS 1236
Cdd:PRK14950 361 VPVPAPQPAKPTAAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPP----------------PVPPRPVAPPVPHT 424
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1237 NPEEPTSPAAAVPTLEEPTSSAAAvltpeelsspaasvPTPEEPASPAAAVSNLEE 1292
Cdd:PRK14950 425 PESAPKLTRAAIPVDEKPKYTPPA--------------PPKEEEKALIADGDVLEQ 466
|
|
| PHA03291 |
PHA03291 |
envelope glycoprotein I; Provisional |
970-1136 |
4.01e-06 |
|
envelope glycoprotein I; Provisional
Pssm-ID: 223033 [Multi-domain] Cd Length: 401 Bit Score: 52.26 E-value: 4.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 970 TPEGPVTPATTvhaPEEPDTAavrvSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTP 1049
Cdd:PHA03291 204 VPATPRPTPRT---TASPETT----PTPSTTTSPPSTTIPAPSTTIAAPQAGTTPEAEGTPAPPTPGGGEAPPANATPAP 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1050 EE---------------PTSPAAAV-----------------PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE-----PT 1092
Cdd:PHA03291 277 EAsryeltvtqiiqiaiPASIIACVflgscacclhrrcrrrrRRPARIYRPPSPVAPSISAVNEAALARLGDElkrhpPE 356
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2245149928 1093 SPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAA 1136
Cdd:PHA03291 357 SPRRSKRRSSQTMVPSLTAISEESEAPAVVELSRSPRRPGGPTA 400
|
|
| PHA03321 |
PHA03321 |
tegument protein VP11/12; Provisional |
963-1212 |
4.03e-06 |
|
tegument protein VP11/12; Provisional
Pssm-ID: 223041 [Multi-domain] Cd Length: 694 Bit Score: 52.65 E-value: 4.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 963 PITEEDGTPEGP--VTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPeeptSPAAAVPTPEEPTSPA------AAVP 1034
Cdd:PHA03321 434 PAPRRDNDPPPPprARPGSTPACARRARAQRARDAGPEYVDPLGALRRLP----AGAAPPPEPAAAPSPAtyytrmGGGP 509
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1035 PPEEPTSPAAavPTPEEPTSPAAAVPtPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAavptpEEPTSPAAAVPTP 1114
Cdd:PHA03321 510 PRLPPRNRAT--ETLRPDWGPPAAAP-PEQMEDPYLEPDDDRFDRRDGAAAAATSHPREAPA-----PDDDPIYEGVSDS 581
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1115 EEPASpaAAVPTPE--EPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATL 1192
Cdd:PHA03321 582 EEPVY--EEIPTPRvyQNPLPRPMEGAGEPPDLDAPTSPWVEEENPIYGWGDSPLFSPPPAARFPPPDPALSPEPPALPA 659
|
250 260
....*....|....*....|....*.
gi 2245149928 1193 EEPTSPA------ASVPTPAAMVATL 1212
Cdd:PHA03321 660 HRPRPGAlapdgpANLAALSAMLTKL 685
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
971-1130 |
4.26e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 52.66 E-value: 4.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 971 PEGPVTPATTvhAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPPPEEPTSPAAAVPTP- 1049
Cdd:PRK14948 361 PSAFISEIAN--ASAPANPTPAPNPSPPPAPIQPSAPKTKQAATTPSPP-PAKASPPIPVPAEPTEPSPTPPANAANAPp 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1050 ---------------EEPT------------------------------------------------------------- 1053
Cdd:PRK14948 438 slnleelwqqilaklELPStrmllsqqaelvsldsnraviavspnwlgmvqsrkplleqafakvlgrsiklnlesqsgsa 517
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1054 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEP 1130
Cdd:PRK14948 518 SNTAKTPPPPQKSPPPPAPTPPLPQPTATAPPPTPPPPPPTATQASSNAPAQIPADSSPPPPIPEEPTPSPTKDSSP 594
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
1041-1155 |
4.32e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 52.76 E-value: 4.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1041 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEptSPAAAVPTPE-EPTSPAAAVPTPEEPAS 1119
Cdd:PRK14959 379 SAPSGSAAEGPASGGAATIPTPGTQGPQGTAPAAGMTPSSAAPATPAPSA--APSPRVPWDDaPPAPPRSGIPPRPAPRM 456
|
90 100 110
....*....|....*....|....*....|....*.
gi 2245149928 1120 PAAAvPTPEEPASPAAAVPTPeePAFPAPAVPTPEE 1155
Cdd:PRK14959 457 PEAS-PVPGAPDSVASASDAP--PTLGDPSDTAEHT 489
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
890-1044 |
4.43e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 52.56 E-value: 4.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 890 SLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDG 969
Cdd:PRK07994 364 PLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSEP 443
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2245149928 970 TPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAA 1044
Cdd:PRK07994 444 AAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTPELAAKLAA 518
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
982-1117 |
4.57e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 52.47 E-value: 4.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 982 HAPEEPDTAAVRVStPEEPASPAAAVPTPEEPTsPAAAVPTPEePTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPT 1061
Cdd:PRK14971 361 QLTQKGDDASGGRG-PKQHIKPVFTQPAAAPQP-SAAAAASPS-PSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVPV 437
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1062 PEEPTSPAAAVPTPEEPTSPAAAVPTP-EEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1117
Cdd:PRK14971 438 NPPSTAPQAVRPAQFKEEKKIPVSKVSsLGPSTLRPIQEKAEQATGNIKEAPTGTQK 494
|
|
| PRK11901 |
PRK11901 |
hypothetical protein; Reviewed |
1004-1138 |
4.62e-06 |
|
hypothetical protein; Reviewed
Pssm-ID: 237015 [Multi-domain] Cd Length: 327 Bit Score: 51.61 E-value: 4.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1004 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTP-------EEP----------------TSPAAAVP 1060
Cdd:PRK11901 91 NQSSPSAANNTSDGHDASGVKNTAPPQDISAPPISPTPTQAAPPQTpngqqriELPgnisdalsqqqgqvnaASQNAQGN 170
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 1061 TPEEPTSPAAaVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPtpeePASPAAAVPTPeEPASPAAAVP 1138
Cdd:PRK11901 171 TSTLPTAPAT-VAPSKGAKVPATAETHPTPPQKPATKKPAVNHHKTATVAVP----PATSGKPKSGA-ASARALSSAP 242
|
|
| KREPA2 |
cd23959 |
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of ... |
1114-1308 |
4.75e-06 |
|
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of the parasitic protozoan's KREPA RNA editing catalytic complex (RECC). Kinetoplastid RNA editing (KRE) proteins occur as pairs or sets of related proteins in multiple complexes. KREPA complex is composed of six components (KREPA1-6), which share a conserved C-terminal region containing an oligonucleotide-binding (OB)-fold-like domain. KREPAs are responsible for the site-specific insertion and deletion of U nucleotides in the kinetoplastid mitochondria pre-messenger RNA. Apart from the conserved C-terminal OB-fold domain, KREPA1, KREPA2, and KREPA3 contain two conserved C2H2 zinc-finger domains. KREPA2 and kinetoplastid RNA editing ligase 1 (KREL1) are specific for ligation post-U-deletion and are paralogous to KREL2 and KREPA1 that are specific for ligation post-U-insertion. KREPA2, is critical for RECC stability and KREL1 integration into the complex.
Pssm-ID: 467780 [Multi-domain] Cd Length: 424 Bit Score: 52.18 E-value: 4.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1114 PEEPASPaaavptPEEPASPAAAvPTPEEPAFPAPAVPTPEESASAAVA--------VPTPEESASP--AAAVPTP--AE 1181
Cdd:cd23959 50 PSDQEEP------LYGAVSPEGE-NPFDGPGLVTASTVSDCYVGNANFYevdmsdafAMAPDESLGPfrAARVPNPfsAS 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1182 SASFAAVVATL----------EEPTSPAASVPTPaamvatleeFTSPAASVPTSEEpASLAAAVSNPEEPTSPAAAVPTL 1251
Cdd:cd23959 123 SSTQRETHKTAqvappkaepqTAPVTPFGQLPMF---------GQHPPPAKPLPAA-AAAQQSSASPGEVASPFASGTVS 192
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1252 EEPTSSAAAVLTPEELS---SPAASVPTPEepASPAAAVSNLEEPASPAAAVPTPEVAAI 1308
Cdd:cd23959 193 ASPFATATDTAPSSGAPdgfPAEASAPSPF--AAPASAASFPAAPVANGEAATPTHACTI 250
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
1198-1371 |
4.78e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 52.56 E-value: 4.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1198 PAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTP 1277
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKK 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1278 EEPASPAAAvsnleepaSPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSV---PISEE 1354
Cdd:PRK07994 441 SEPAAASRA--------RPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALeheKTPEL 512
|
170
....*....|....*..
gi 2245149928 1355 GTPVLEEASSTGMWIKE 1371
Cdd:PRK07994 513 AAKLAAEAIERDPWAAL 529
|
|
| PHA03269 |
PHA03269 |
envelope glycoprotein C; Provisional |
1109-1255 |
4.90e-06 |
|
envelope glycoprotein C; Provisional
Pssm-ID: 165527 [Multi-domain] Cd Length: 566 Bit Score: 52.42 E-value: 4.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1109 AAVPTPeepaspaaaVPTPEEPASPAAAVPTPeepafpAPAvPTPEESASAAVAV-PTPEESASPAAAV-PTPAESASFA 1186
Cdd:PHA03269 20 ANLNTN---------IPIPELHTSAATQKPDP------APA-PHQAASRAPDPAVaPTSAASRKPDLAQaPTPAASEKFD 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1187 AVVAtleePTSPAASVPTPAAMVATLEEFTSPAASVPTS---EEPASLAAAVSNPEEPTSPAAAVPTLEEPT 1255
Cdd:PHA03269 84 PAPA----PHQAASRAPDPAVAPQLAAAPKPDAAEAFTSaaqAHEAPADAGTSAASKKPDPAAHTQHSPPPF 151
|
|
| PHA01929 |
PHA01929 |
putative scaffolding protein |
1009-1136 |
5.00e-06 |
|
putative scaffolding protein
Pssm-ID: 177328 Cd Length: 306 Bit Score: 51.59 E-value: 5.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1009 TPEEPTSPAAaVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPA-AAVPTPEEPTSPAAAVPTPEEPTSPAAavPT 1087
Cdd:PHA01929 2 TQNEQQLPPG-LAGLVANVPPAAAPTPQPNPVIQPQAPVQPGQPGAPQqLAIPTQQPQPVPTSAMTPHVVQQAPAQ--PA 78
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2245149928 1088 PEEPTSPAAAVPTPEEPTSPAAAVPtPEEPASPAAAVPTPEEPASPAAA 1136
Cdd:PHA01929 79 PAAPPAAGAALPEALEVPPPPAFTP-NGEIVGTLAGNLEGDPQLAPSVS 126
|
|
| DUF4045 |
pfam13254 |
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. ... |
1015-1315 |
5.02e-06 |
|
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. This domain family is found in bacteria and eukaryotes, and is typically between 384 and 430 amino acids in length.
Pssm-ID: 433066 [Multi-domain] Cd Length: 415 Bit Score: 52.09 E-value: 5.02e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1015 SPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEePTS---PAAAVPTPEEPTSPAAAVPTPEEPTSPA-AAVPTPEE 1090
Cdd:pfam13254 41 SFASNRGSVAGPSGSLSPGLSPTKLSREGSPESTSR-PSSshsEATIVRHSKDDERPSTPDEGFVKPALPRhSRSSSALS 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1091 PTSpaAAVPTPEEPTSPaaavPTPEEPASPAAAVPT-----------PEEPaSPAAAVPTPEEPAFPAPAVPTPEESASA 1159
Cdd:pfam13254 120 NTG--SEEDSPSLPTSP----PSPSKTMDPKRWSPTksswlesalnrPESP-KPKAQPSQPAQPAWMKELNKIRQSRASV 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1160 AVAVPtpeesaSPAAAVPTpaesasfaavvATLEEPTSPAASVPTPAamvatleEFTSPAASVPTSEEPASLAAAVSNPE 1239
Cdd:pfam13254 193 DLGRP------NSFKEVTP-----------VGLMRSPAPGGHSKSPS-------VSGISADSSPTKEEPSEEADTLSTDK 248
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1240 EPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTP-EVAAIPAASVPT 1315
Cdd:pfam13254 249 EQSPAPTSASEPPPKTKELPKDSEEPAAPSKSAEASTEKKEPDTESSPETSSEKSAPSLLSPVSkASIDKPLSSPDR 325
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
1013-1126 |
5.29e-06 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 52.28 E-value: 5.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1013 PTSPAAAVPTPEEPTSPAAAVPPP----EEPTSPAAAVPTPeeptSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1088
Cdd:PRK06995 53 PPAAAAPAAAQPPPAAAPAAVSRPaapaAEPAPWLVEHAKR----LTAQREQLVARAAAPAAPEAQAPAAPAERAAAENA 128
|
90 100 110
....*....|....*....|....*....|....*...
gi 2245149928 1089 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPT 1126
Cdd:PRK06995 129 ARRLARAAAAAPRPRVPADAAAAVADAVKARIERIVND 166
|
|
| PRK11633 |
PRK11633 |
cell division protein DedD; Provisional |
995-1082 |
5.33e-06 |
|
cell division protein DedD; Provisional
Pssm-ID: 236940 [Multi-domain] Cd Length: 226 Bit Score: 50.39 E-value: 5.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 995 STPEEPASPAAAVPTPEEPTSPAAAVPTPEeptSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAaavPT 1074
Cdd:PRK11633 65 TQPPEGAAEAVRAGDAAAPSLDPATVAPPN---TPVEPEPAPVEPPKPKPVEKPKPKPKPQQKVEAPPAPKPEPK---PV 138
|
....*...
gi 2245149928 1075 PEEPTSPA 1082
Cdd:PRK11633 139 VEEKAAPT 146
|
|
| DUF3729 |
pfam12526 |
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ... |
1027-1114 |
5.38e-06 |
|
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.
Pssm-ID: 372164 [Multi-domain] Cd Length: 115 Bit Score: 48.15 E-value: 5.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1027 TSPAAAVPPPEEPTSPAAAvPTPEEPTSPAAAVPTPEEPTSPAAavPTPEEPTSPAAAVPTPEEPTSPaaavPTPEEPTS 1106
Cdd:pfam12526 22 TSGFSSCFSPPESAHPDPP-PPVGDPRPPVVDTPPPVSAVWVLP--PPSEPAAPEPDLVPPVTGPAGP----PSPLAPPA 94
|
....*...
gi 2245149928 1107 PAAAVPTP 1114
Cdd:pfam12526 95 PAQKPPLP 102
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
896-1070 |
5.43e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 52.18 E-value: 5.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 896 VTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEgmsAVAGFSPEWAALAITVPITEEDGTPEgPV 975
Cdd:PRK07994 364 PLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAP---AVPLPETTSQLLAARQQLQRAQGATK-AK 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 976 TPATTVHAPEEPDTAAV-RVSTPEEPASPAAAVPTPEEPTSPAAAVPtpeeptspaaAVPPPEEPTSPAAAVPTPEEPTS 1054
Cdd:PRK07994 440 KSEPAAASRARPVNSALeRLASVRPAPSALEKAPAKKEAYRWKATNP----------VEVKKEPVATPKALKKALEHEKT 509
|
170
....*....|....*.
gi 2245149928 1055 PAAAVPTPEEPTSPAA 1070
Cdd:PRK07994 510 PELAAKLAAEAIERDP 525
|
|
| PRK11633 |
PRK11633 |
cell division protein DedD; Provisional |
1033-1134 |
5.48e-06 |
|
cell division protein DedD; Provisional
Pssm-ID: 236940 [Multi-domain] Cd Length: 226 Bit Score: 50.39 E-value: 5.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1033 VPPP---EEPTS-PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1108
Cdd:PRK11633 44 VPKPgdrDEPDMmPAATQALPTQPPEGAAEAVRAGDAAAPSLDPATVAPPNTPVEPEPAPVEPPKPKPVEKPKPKPKPQQ 123
|
90 100
....*....|....*....|....*.
gi 2245149928 1109 AAVPTPEEPASPAaavPTPEEPASPA 1134
Cdd:PRK11633 124 KVEAPPAPKPEPK---PVVEEKAAPT 146
|
|
| KLF9_13_N-like |
cd21975 |
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like ... |
1028-1181 |
5.81e-06 |
|
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like transcription factors (KLFs) belong to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the related N-terminal domains of KLF9, KLF13, KLF14, KLF16, and similar proteins.
Pssm-ID: 409240 [Multi-domain] Cd Length: 163 Bit Score: 49.30 E-value: 5.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1028 SPAAAVP---PPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPeeptSPAAAVPTPEEPTSPAAAVPTPEEP 1104
Cdd:cd21975 11 SISAGAVvhgVRPDPEGAGLAAGLDVRATREVAKGPGPPGPAWKPDGADSP----GLVTAAPHLLAANVLAPLRGPSVEG 86
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 1105 TSPAA--AVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESAsaavavPTPEESASPAAAVPTPAE 1181
Cdd:cd21975 87 SSLESgdADMGSDSDVAPASGAAASTSPESSSDAASSPSPLSLLHPGEAGLEPER------PRPRVRRGVRRRGVTPAA 159
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1532-1830 |
6.00e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.37 E-value: 6.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1532 QAEGGRIAQSAELADREKitgQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSE-PVG 1610
Cdd:TIGR02168 667 KTNSSILERRREIEELEE---KIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEaEVE 743
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1611 TQTAKIQQQIIRHKALNEEIVNRKKNVDQA----------IKNGQALLKQTTgEEVLLIQEKLDGIKTRYADITVTSSKA 1680
Cdd:TIGR02168 744 QLEERIAQLSKELTELEAEIEELEERLEEAeeelaeaeaeIEELEAQIEQLK-EELKALREALDELRAELTLLNEEAANL 822
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1681 LRTLEQARQLATKFQSTYEELTGWLREVEEELAT-SGGQSPTGEQIPQFQQRQKELKKEVMEHRLVL-----------DT 1748
Cdd:TIGR02168 823 RERLESLERRIAATERRLEDLEEQIEELSEDIESlAAEIEELEELIEELESELEALLNERASLEEALallrseleelsEE 902
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1749 VNEVSRALLELVpwRAREGLDKLVSDA------------------NEQYKLVSDTIGQRVDEIDAAIQRSQQYeqaadae 1810
Cdd:TIGR02168 903 LRELESKRSELR--RELEELREKLAQLelrleglevridnlqerlSEEYSLTLEEAEALENKIEDDEEEARRR------- 973
|
330 340
....*....|....*....|
gi 2245149928 1811 lawVAETKRKLMALGPIRLE 1830
Cdd:TIGR02168 974 ---LKRLENKIKELGPVNLA 990
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1440-2006 |
6.11e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 52.35 E-value: 6.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1440 GLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAEYKVVKAQIQEQK-LLQ 1518
Cdd:PRK02224 210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLReRLE 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1519 RLLDDRKATVDmlQAEGGRIAQSAELADREKITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSV 1598
Cdd:PRK02224 290 ELEEERDDLLA--EAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAE 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1599 TEKKLANSEpvgtqtAKIQQQIIRHKALNEEI-VNRKKNVDQAIKNGQAllkqttgEEVL-LIQEKLDGIKTRYADITVT 1676
Cdd:PRK02224 368 LESELEEAR------EAVEDRREEIEELEEEIeELRERFGDAPVDLGNA-------EDFLeELREERDELREREAELEAT 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1677 SSKALRTLEQARQLatkfqstYEEltGWLREVEEELAtsggQSPTGEQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRAL 1756
Cdd:PRK02224 435 LRTARERVEEAEAL-------LEA--GKCPECGQPVE----GSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERA 501
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1757 LELVPWRARegldklVSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADaELAWVAETKRKLMALGPIRLEQD-QTT 1835
Cdd:PRK02224 502 EDLVEAEDR------IERLEERREDLEELIAERRETIEEKRERAEELRERAA-ELEAEAEEKREAAAEAEEEAEEArEEV 574
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1836 AQLQVQKAFSIDIIRHKDSMDELFSHRSEifgtcgeeqktvLQEKTESLIQQYEAISLLNSERYARLERAQVLVNQFWET 1915
Cdd:PRK02224 575 AELNSKLAELKERIESLERIRTLLAAIAD------------AEDEIERLREKREALAELNDERRERLAEKRERKRELEAE 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1916 YEELSpwIEETRALIAQLPSpAIDH--EQLRQQQEEMRQLRESIAEHKPHIDKLLKIGPQLKELNpEEGEMVEEKYQKAE 1993
Cdd:PRK02224 643 FDEAR--IEEAREDKERAEE-YLEQveEKLDELREERDDLQAEIGAVENELEELEELRERREALE-NRVEALEALYDEAE 718
|
570
....*....|....*.
gi 2245149928 1994 ---NMYAQIKEEVRQR 2006
Cdd:PRK02224 719 eleSMYGDLRAELRQR 734
|
|
| SAV_2336_NTERM |
NF041121 |
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ... |
990-1077 |
6.22e-06 |
|
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.
Pssm-ID: 469044 [Multi-domain] Cd Length: 473 Bit Score: 51.93 E-value: 6.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 990 AAVRVSTPEEPASPAAAVP-TPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPeePTSP 1068
Cdd:NF041121 17 RAAAPPSPEGPAPTAASQPaTPPPPAAPPSPPGDPPEPPAPEPAPLPAPYPGSLAPPPPPPPGPAGAAPGAALP--VRVP 94
|
90
....*....|
gi 2245149928 1069 AAAV-PTPEE 1077
Cdd:NF041121 95 APPAlPNPLE 104
|
|
| PRK14949 |
PRK14949 |
DNA polymerase III subunits gamma and tau; Provisional |
810-1227 |
6.47e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237863 [Multi-domain] Cd Length: 944 Bit Score: 52.42 E-value: 6.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 810 PEKQVTKAGNTEPVlEEWIPVLQRPSRTAA---VPTVKDALDAALPSPEEGTSIAAVPAPEgTAVVAALVPFPHEDilVA 886
Cdd:PRK14949 359 PEKPVKRWQVDDPA-EISLPEGQTPSALAAavqAPHANEPQFVNAAPAEKKTALTEQTTAQ-QQVQAANAEAVAEA--DA 434
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 887 SIVSLEEEDVTAAAVSAPERA----------------------------TVPAVTVSVPEGTAAVAAVSS-PEETAPAVA 937
Cdd:PRK14949 435 SAEPADTVEQALDDESELLAAlnaeqavilsqaqsqgfeasssldadnsAVPEQIDSTAEQSVVNPSVTDtQVDDTSASN 514
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 938 AAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPA-----TTVHAPEEPDTAAVRVSTPEE-PASPAAAVPTPE 1011
Cdd:PRK14949 515 NSAADNTVDDNYSAEDTLESNGLDEGDYAQDSAPLDAYQDDyvafsSESYNALSDDEQHSANVQSAQsAAEAQPSSQSLS 594
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1012 EPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAavptpeEP 1091
Cdd:PRK14949 595 PISAVTTAAASLADDDILDAVLAARDSLLSDLDALSPKEGDGKKSSADRKPKTPPSRAPPASLSKPASSPDA------SQ 668
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1092 TSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPaaavptP-EEPAFPAPAVPTPEESASAAVAVPTPEESA 1170
Cdd:PRK14949 669 TSASFDLDPDFELATHQSVPEAALASGSAPAPPPVPDPYDRP------PwEEAPEVASANDGPNNAAEGNLSESVEDASN 742
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1171 SPAAAVPTPAEsasfaAVVATLEEPTSPAASvptpAAMVATLEEFTSPAASVPTSEE 1227
Cdd:PRK14949 743 SELQAVEQQAT-----HQPQVQAEAQSPAST----TALTQTSSEVQDTELNLVLLSS 790
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
1196-1335 |
6.49e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 52.12 E-value: 6.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1196 TSPAASVPTPAAMV-ATLEEFTSPAASVPTSEEPaslAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASV 1274
Cdd:PRK14950 343 TTSYGQLPLELAVIeALLVPVPAPQPAKPTAAAP---SPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAP 419
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2245149928 1275 PTPEEPASPaaavsnleePASPAAAVPTPEvAAIPAASVPTPEVPAIPAAAVPPMEEVSPI 1335
Cdd:PRK14950 420 PVPHTPESA---------PKLTRAAIPVDE-KPKYTPPAPPKEEEKALIADGDVLEQLEAI 470
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
1079-1164 |
6.78e-06 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 51.18 E-value: 6.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1079 TSPAAAVPTPEEPTSPAAAVPTPeEPTSPAAAVPTPEEPASPAAAV-PTPEEPASPAAAVPTPEEPAFPAPAVPTPEESA 1157
Cdd:PRK10856 166 TSTTTDPATTPAPAAPVDTTPTN-SQTPAVATAPAPAVDPQQNAVVaPSQANVDTAATPAPAAPATPDGAAPLPTDQAGV 244
|
....*..
gi 2245149928 1158 SAAVAVP 1164
Cdd:PRK10856 245 STPAADP 251
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
1026-1124 |
7.21e-06 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 51.18 E-value: 7.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1026 PTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTP--EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPee 1103
Cdd:PRK10856 163 PLDTSTTTDPATTPAPAAPVDTTPTNSQTPAVATAPApaVDPQQNAVVAPSQANVDTAATPAPAAPATPDGAAPLPTD-- 240
|
90 100
....*....|....*....|.
gi 2245149928 1104 ptspAAAVPTPeePASPAAAV 1124
Cdd:PRK10856 241 ----QAGVSTP--AADPNALV 255
|
|
| PRK10905 |
PRK10905 |
cell division protein DamX; Validated |
898-1062 |
7.74e-06 |
|
cell division protein DamX; Validated
Pssm-ID: 236792 [Multi-domain] Cd Length: 328 Bit Score: 51.09 E-value: 7.74e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 898 AAAVSAPERATVPAVTVSVPEGTAAVAA-----VSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPE 972
Cdd:PRK10905 62 QTAGNTQQDVSLPPISSTPTQGQTPVATdgqqrVEVQGDLNNALTQPQNQQQLNNVAVNSTLPTEPATVAPVRNGNASRQ 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 973 GPVTPAttvhAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTspaAAVPTPEEPTSPAAAVPPPEEPTSPA---AAVPTP 1049
Cdd:PRK10905 142 TAKTQT----AERPATTRPARKQAVIEPKKPQATAKTEPKPV---AQTPKRTEPAAPVASTKAPAATSTPApkeTATTAP 214
|
170
....*....|...
gi 2245149928 1050 EEPTSPAAAVPTP 1062
Cdd:PRK10905 215 VQTASPAQTTATP 227
|
|
| KLF9_13_N-like |
cd21975 |
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like ... |
1023-1160 |
7.88e-06 |
|
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like transcription factors (KLFs) belong to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the related N-terminal domains of KLF9, KLF13, KLF14, KLF16, and similar proteins.
Pssm-ID: 409240 [Multi-domain] Cd Length: 163 Bit Score: 48.92 E-value: 7.88e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1023 PEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT--------SPAAAVPTPEEPTSPAAAVPTPEEPTSP 1094
Cdd:cd21975 22 RPDPEGAGLAAGLDVRATREVAKGPGPPGPAWKPDGADSPGLVTaaphllaaNVLAPLRGPSVEGSSLESGDADMGSDSD 101
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1095 AAavptpeePTSPAAAVPTPEEpASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAA 1160
Cdd:cd21975 102 VA-------PASGAAASTSPES-SSDAASSPSPLSLLHPGEAGLEPERPRPRVRRGVRRRGVTPAA 159
|
|
| PHA01929 |
PHA01929 |
putative scaffolding protein |
1048-1175 |
8.01e-06 |
|
putative scaffolding protein
Pssm-ID: 177328 Cd Length: 306 Bit Score: 50.82 E-value: 8.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1048 TPEEPTSPAAaVPTPEEPTSPAAAvPTPE-EPTSPAAAVPTPEEPTSPA-AAVPTPEE---PTSPAAAVPTPEEPASPAA 1122
Cdd:PHA01929 2 TQNEQQLPPG-LAGLVANVPPAAA-PTPQpNPVIQPQAPVQPGQPGAPQqLAIPTQQPqpvPTSAMTPHVVQQAPAQPAP 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1123 AVPTPEEPASPAAAVPTPEepafpaPAVPTPEESASAAVAVPTPEESASPAAA 1175
Cdd:PHA01929 80 AAPPAAGAALPEALEVPPP------PAFTPNGEIVGTLAGNLEGDPQLAPSVS 126
|
|
| PPE |
COG5651 |
PPE-repeat protein [Function unknown]; |
895-1123 |
8.29e-06 |
|
PPE-repeat protein [Function unknown];
Pssm-ID: 444372 [Multi-domain] Cd Length: 385 Bit Score: 51.05 E-value: 8.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 895 DVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVA-AAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEG 973
Cdd:COG5651 156 AASAAAVALTPFTQPPPTITNPGGLLGAQNAGSGNTSSNPGFAnLGLTGLNQVGIGGLNSGSGPIGLNSGPGNTGFAGTG 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 974 PVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPT 1053
Cdd:COG5651 236 AAAGAAAAAAAAAAAAGAGASAALASLAATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAAATGLGLGAGGA 315
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1054 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAA 1123
Cdd:COG5651 316 AGAAGATGAGAALGAGAAAAAAGAAAGAGAAAAAAAGGAGGGGGGALGAGGGGGSAGAAAGAASGGGAAA 385
|
|
| rad23 |
TIGR00601 |
UV excision repair protein Rad23; All proteins in this family for which functions are known ... |
1105-1298 |
8.32e-06 |
|
UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273167 [Multi-domain] Cd Length: 378 Bit Score: 51.05 E-value: 8.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1105 TSPAAAVPTPEEPASPAAAVPTPeEPASPAAAVPTPEEPafPAPAVPtPEESASAAVAVPTPEesaSPAAAVPTPAESAS 1184
Cdd:TIGR00601 75 SKPKTGTGKVAPPAATPTSAPTP-TPSPPASPASGMSAA--PASAVE-EKSPSEESATATAPE---SPSTSVPSSGSDAA 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1185 FAAVVATLEEptspaasvptpaamvATLEEFTSpaASVPTSEEPASLAAAVSNPEE---------PTSPAAAvptleEPT 1255
Cdd:TIGR00601 148 STLVVGSERE---------------TTIEEIME--MGYEREEVERALRAAFNNPDRaveylltgiPEDPEQP-----EPV 205
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2245149928 1256 SSAAAvltpeelSSPAASVPTPEEPA-SPAAAVSNLEEPASPAA 1298
Cdd:TIGR00601 206 QQTAA-------STAAATTETPQHGSvFEQAAQGGTEQPATEAA 242
|
|
| SAV_2336_NTERM |
NF041121 |
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ... |
1014-1103 |
8.62e-06 |
|
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.
Pssm-ID: 469044 [Multi-domain] Cd Length: 473 Bit Score: 51.54 E-value: 8.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1014 TSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPeePTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP-T 1092
Cdd:NF041121 15 MGRAAAPPSPEGPAPTAASQPATPPPPAAPPSPPGD--PPEPPAPEPAPLPAPYPGSLAPPPPPPPGPAGAAPGAALPvR 92
|
90
....*....|..
gi 2245149928 1093 SPAAAV-PTPEE 1103
Cdd:NF041121 93 VPAPPAlPNPLE 104
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
1103-1184 |
8.73e-06 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 51.92 E-value: 8.73e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1103 EPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPtpeesaspaAAVPTPAES 1182
Cdd:COG5373 36 ELAEAAEAASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEAEP---------AAAPAAASS 106
|
..
gi 2245149928 1183 AS 1184
Cdd:COG5373 107 FE 108
|
|
| Streccoc_I_II |
NF033804 |
antigen I/II family LPXTG-anchored adhesin; Members of the antigen I/II family are adhesins ... |
1156-1316 |
9.05e-06 |
|
antigen I/II family LPXTG-anchored adhesin; Members of the antigen I/II family are adhesins with a glucan-binding domain, two types of repetitive regions, an isopeptide bond-forming domain associated with shear resistance, and a C-terminal LPXTG motif for anchoring to the cell wall. They occur in oral Streptococci, and tend to be major cell surface adhesins. Members of this family include SspA and SspB from Streptococcus gordonii, antigen I/II from S. mutans, etc.
Pssm-ID: 468188 [Multi-domain] Cd Length: 1552 Bit Score: 51.87 E-value: 9.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1156 SASAAVAVPTPEESASPAAAVPTP-------AESASFAAV---VATLEEPTSPAAsvPT-PAAMVATLEEFTSPAASVPT 1224
Cdd:NF033804 783 AISATNVMPSDEMPAVPGRDNTEGkkpniwySLNGKIRAVnvpKITKEKPTPPVA--PTaPQAPTYEVEKPLEPAPVAPT 860
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1225 SEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPE 1304
Cdd:NF033804 861 YENEPTPPVKTPDQPEPSKPEEPTYETEKPLEPAPVAPTYENEPTPPVKTPDQPEPSKPEEPTYETEKPLEPAPVAPSYE 940
|
170
....*....|..
gi 2245149928 1305 vaaipaaSVPTP 1316
Cdd:NF033804 941 -------NEPTP 945
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
1038-1110 |
9.26e-06 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 51.92 E-value: 9.26e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1038 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEeptsPAAA 1110
Cdd:COG5373 36 ELAEAAEAASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEAEPAAA----PAAA 104
|
|
| KLF14_N |
cd21576 |
N-terminal domain of Kruppel-like factor 14; Kruppel-like factor 14 (KLF14; also known as ... |
1125-1298 |
9.41e-06 |
|
N-terminal domain of Kruppel-like factor 14; Kruppel-like factor 14 (KLF14; also known as Krueppel-like factor 14 or basic transcription element-binding protein 5/BTEB5) is a protein that in humans is encoded by the KLF14 gene. KLF14 regulates the transcription of various genes, including TGFbetaRII (the type II receptor for TGFbeta). KLF14 is expressed in many tissues, lacks introns, and is subject to parent-specific expression. It also appears to be a master regulator of gene expression in adipose tissue. KLF14 is associated with coronary artery disease, hypercholesterolemia, and type 2 diabetes. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. KLF14 belongs to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the N-terminal domain of KLF14.
Pssm-ID: 409238 [Multi-domain] Cd Length: 195 Bit Score: 49.05 E-value: 9.41e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1125 PTPEEPASPAAAV--PTPEEPAFPAPAVPTPEeSASAAVAVPTPeeSASPAAAVPTPAESASFAAVVATLEEpTSPAASV 1202
Cdd:cd21576 29 PDPEGAGGAAGSEvgAAPPESALPGPGPPGPA-WVPPLLQVPAP--SPGAGGAAPHLLAASVLADLRGGAGE-GSREDSG 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1203 PTPAAMVATLEeftsPA-ASVPT--SEE-PASLAAAVSNPEEpTSPAAAVPtleeptSSAAAVLTPEELSSPAASVPtpE 1278
Cdd:cd21576 105 EAPRASSGSSD----PArGSSPTlgSEPaPASGEDAVSGPES-SFGAPAIP------SAPAAPGAPAVSGEVPGGAP--G 171
|
170 180
....*....|....*....|
gi 2245149928 1279 EPASPAAAVSNLEEPASPAA 1298
Cdd:cd21576 172 AGPAPAAGPAPRRRPVTPAA 191
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1149-1316 |
1.01e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 51.53 E-value: 1.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1149 AVPtpeeSASAAVAVPTPEESAS---PAAAVPTPAESASFAAVV-ATLEE---PTSP-------------AASVPTPAAM 1208
Cdd:PRK07764 299 AVP----DAAERGLVDAPADQLDrmrAQAQRLGPAELTRAADVVnDGLTEmrgATSPrlllellcarmllPSASDDERGL 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1209 VATLEEF---TSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAvltpeelssPAASVPTPEEPASPAA 1285
Cdd:PRK07764 375 LARLERLerrLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAP---------QPAPAPAPAPAPPSPA 445
|
170 180 190
....*....|....*....|....*....|..
gi 2245149928 1286 AVSNLE-EPASPAAAVPTPEVAAIPAASVPTP 1316
Cdd:PRK07764 446 GNAPAGgAPSPPPAAAPSAQPAPAPAAAPEPT 477
|
|
| PHA01929 |
PHA01929 |
putative scaffolding protein |
1074-1217 |
1.03e-05 |
|
putative scaffolding protein
Pssm-ID: 177328 Cd Length: 306 Bit Score: 50.44 E-value: 1.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1074 TPEEPTSPAAaVPTPEEPTSPAAAvPTPE-EPTSPAAAVPTPEEPASPA-AAVPTPEE---PASPAAAVPTPEEPAFPAP 1148
Cdd:PHA01929 2 TQNEQQLPPG-LAGLVANVPPAAA-PTPQpNPVIQPQAPVQPGQPGAPQqLAIPTQQPqpvPTSAMTPHVVQQAPAQPAP 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 1149 AVPTPeesasAAVAVPTPEESASPAAAVPTPAESASFAAVVatleeptspaASVPTPAAMVATLEEFTS 1217
Cdd:PHA01929 80 AAPPA-----AGAALPEALEVPPPPAFTPNGEIVGTLAGNL----------EGDPQLAPSVSYLEAFSG 133
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
1039-1137 |
1.04e-05 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 50.80 E-value: 1.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1039 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP--EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPee 1116
Cdd:PRK10856 163 PLDTSTTTDPATTPAPAAPVDTTPTNSQTPAVATAPApaVDPQQNAVVAPSQANVDTAATPAPAAPATPDGAAPLPTD-- 240
|
90 100
....*....|....*....|.
gi 2245149928 1117 paspAAAVPTPeePASPAAAV 1137
Cdd:PRK10856 241 ----QAGVSTP--AADPNALV 255
|
|
| SAV_2336_NTERM |
NF041121 |
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ... |
1030-1129 |
1.05e-05 |
|
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.
Pssm-ID: 469044 [Multi-domain] Cd Length: 473 Bit Score: 51.16 E-value: 1.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1030 AAAVPPPEEPTSPAAavPTPEEPTSPAaavpTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1109
Cdd:NF041121 12 AAQMGRAAAPPSPEG--PAPTAASQPA----TPPPPAAPPSPPGDPPEPPAPEPAPLPAPYPGSLAPPPPPPPGPAGAAP 85
|
90 100
....*....|....*....|.
gi 2245149928 1110 AVPTPeePASPAAAV-PTPEE 1129
Cdd:NF041121 86 GAALP--VRVPAPPAlPNPLE 104
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
1025-1097 |
1.09e-05 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 51.54 E-value: 1.09e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1025 EPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEeptsPAAA 1097
Cdd:COG5373 36 ELAEAAEAASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEAEPAAA----PAAA 104
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
1078-1172 |
1.13e-05 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 50.41 E-value: 1.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1078 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPeesa 1157
Cdd:PRK10856 163 PLDTSTTTDPATTPAPAAPVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPSQANVDTAATPAPAAPATPDGAAPLP---- 238
|
90
....*....|....*
gi 2245149928 1158 SAAVAVPTPEESASP 1172
Cdd:PRK10856 239 TDQAGVSTPAADPNA 253
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
987-1081 |
1.13e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 51.22 E-value: 1.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 987 PDTAAVRVSTPEEPASPAAAVP-TPEEPTSPAAAVPTPE-EPTSPAAAVPPPEEPTSPAAAvPTPEEPTSPAAAVPTPee 1064
Cdd:PRK14959 400 PGTQGPQGTAPAAGMTPSSAAPaTPAPSAAPSPRVPWDDaPPAPPRSGIPPRPAPRMPEAS-PVPGAPDSVASASDAP-- 476
|
90
....*....|....*..
gi 2245149928 1065 PTSPAAAVPTPEEPTSP 1081
Cdd:PRK14959 477 PTLGDPSDTAEHTPSGP 493
|
|
| MISS |
pfam15822 |
MAPK-interacting and spindle-stabilising protein-like; MISS is a family of eukaryotic ... |
969-1065 |
1.16e-05 |
|
MAPK-interacting and spindle-stabilising protein-like; MISS is a family of eukaryotic MAPK-interacting and spindle-stabilising protein-like proteins. MISS is rich in prolines and has four potential MAPK-phosphorylation sites, a MAPK-docking site, a PEST sequence (PEST motif) and a bipartite nuclear localization signal. The endogenous protein accumulates during mouse meiotic maturation and is found as discrete dots on the MII spindle. MISS is the first example of a physiological MAPK-substrate that is stabilized in MII that specifically regulates MII spindle integrity during the CSF arrest.
Pssm-ID: 318115 [Multi-domain] Cd Length: 238 Bit Score: 49.60 E-value: 1.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 969 GTPEGPVTPATT------VHAPEEPdTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTP-----EEPTSPAAAVPPPE 1037
Cdd:pfam15822 127 GAPTDPAAAAPSgpwgsmSSGPWAP-GMGGQYPAPNMPYPSPGPYPAVPPPQSPGAAPPVPwgtvpPGPWGPPAPYPDPT 205
|
90 100 110
....*....|....*....|....*....|..
gi 2245149928 1038 EPTSPAAAVPTPEEP----TSPAAAVPTPEEP 1065
Cdd:pfam15822 206 GSYPMPGLYPTPNNPfqvpSGPSGAPPMPGGP 237
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
1030-1093 |
1.21e-05 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 50.84 E-value: 1.21e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 1030 AAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1093
Cdd:PTZ00144 120 TGGAPPAAAPAAAAAAKAEKTTPEKPKAAAPTPEPPAASKPTPPAAAKPPEPAPAAKPPPTPVA 183
|
|
| EF-hand_8 |
pfam13833 |
EF-hand domain pair; |
3184-3233 |
1.21e-05 |
|
EF-hand domain pair;
Pssm-ID: 404678 [Multi-domain] Cd Length: 54 Bit Score: 45.00 E-value: 1.21e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 2245149928 3184 QDGKITRQEFIDGILASKFP-TTKLEMTAVADIFDRDGDGYIDYYEFVAAL 3233
Cdd:pfam13833 1 EKGVITREELKRALALLGLKdLSEDEVDILFREFDTDGDGYISFDEFCVLL 51
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
974-1060 |
1.25e-05 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 50.41 E-value: 1.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 974 PVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTP--EEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEE 1051
Cdd:PRK10856 163 PLDTSTTTDPATTPAPAAPVDTTPTNSQTPAVATAPApaVDPQQNAVVAPSQANVDTAATPAPAAPATPDGAAPLPTDQA 242
|
....*....
gi 2245149928 1052 PTSPAAAVP 1060
Cdd:PRK10856 243 GVSTPAADP 251
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
1066-1161 |
1.29e-05 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 50.41 E-value: 1.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1066 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEpaf 1145
Cdd:PRK10856 166 TSTTTDPATTPAPAAPVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPSQANVDTAATPAPAAPATPDGAAPLPTDQA--- 242
|
90
....*....|....*.
gi 2245149928 1146 papAVPTPEESASAAV 1161
Cdd:PRK10856 243 ---GVSTPAADPNALV 255
|
|
| PRK11855 |
PRK11855 |
dihydrolipoamide acetyltransferase; Reviewed |
852-1124 |
1.31e-05 |
|
dihydrolipoamide acetyltransferase; Reviewed
Pssm-ID: 237000 [Multi-domain] Cd Length: 547 Bit Score: 50.98 E-value: 1.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 852 PSPEEGTsIAAVPAPEG-TAVVAALvpfphedilvasIVSLEEEDVTAAAvSAPERATVPAvtvsvpegtAAVAAVSSPE 930
Cdd:PRK11855 48 PSPAAGV-VKEIKVKVGdTVSVGGL------------LAVIEAAGAAAAA-AAPAAAAAPA---------AAAAAAPAPA 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 931 ETAPAVAAAitqegmSAVAGFSPewaalaITVP-ITEEDgtpEGPVT-----PATTVhapeEPDTAAVRVSTP---EEPA 1001
Cdd:PRK11855 105 AAAPAAAAA------AAGGGVVE------VKVPdIGEIT---EVEVIewlvkVGDTV----EEDQSLITVETDkatMEIP 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1002 SPAA------------AVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAvptPEEPTSPAAAVPTPEEPTSPA 1069
Cdd:PRK11855 166 SPVAgvvkeikvkvgdKVSVGSLLVVIEVAAAAPAAAAAPAAAAPAAAAAAAPAPA---PAAAAAPAAAAPAAAAAPGKA 242
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1070 AAVptpeeptSPA------------AAVP--------TPEEPTSPA-AAVPTPEEPTSPAAAVPTPEEPASPAAAV 1124
Cdd:PRK11855 243 PHA-------SPAvrrlarelgvdlSQVKgtgkkgriTKEDVQAFVkGAMSAAAAAAAAAAAAGGGGLGLLPWPKV 311
|
|
| DUF3432 |
pfam11914 |
Domain of unknown function (DUF3432); This presumed domain is functionally uncharacterized. ... |
1095-1191 |
1.33e-05 |
|
Domain of unknown function (DUF3432); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is about 100 amino acids in length. This domain is found associated with pfam00096. This domain has two conserved sequence motifs: YPSPV and PSP.
Pssm-ID: 403204 [Multi-domain] Cd Length: 98 Bit Score: 46.25 E-value: 1.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1095 AAAVPTPEEPTSPAAAVPTPEEPASPAaavPTPEEPASPAAAV-PTPEEPAFPAPAVPTPEESASAAVavptpeeSASPA 1173
Cdd:pfam11914 7 SAVSSISSYSSSVTTSYPSPITTSYPS---PVSTSYSSPVPSSyPSPVHTSFPSPSIATTYPSVTTTF-------QTQVA 76
|
90
....*....|....*...
gi 2245149928 1174 AAVPTPAESASFAAVVAT 1191
Cdd:pfam11914 77 SSFPSSVVTNSYSSQVTT 94
|
|
| DamX |
COG3266 |
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ... |
1067-1317 |
1.39e-05 |
|
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442497 [Multi-domain] Cd Length: 455 Bit Score: 50.62 E-value: 1.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1067 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA-VPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAF 1145
Cdd:COG3266 96 LLALLLDLLLLADLLRAAALLLLKLLLLLLTLLLLVLLLLLALLlALLLDLPLLTLLIVLPLLEEQLLLLALQDIQGTLQ 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1146 PAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTS 1225
Cdd:COG3266 176 ALGAVAALLGLRKAEEALALRAGSAAADALALLLLLLASALGEAVAAAAELAALALLAAGAAEVLTARLVLLLLIIGSAL 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1226 EEPASlaAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSpAASVPTPEEPASPAAAVsnlEEPASPAAAVPTPEV 1305
Cdd:COG3266 256 KAPSQ--ASSASAPATTSLGEQQEVSLPPAVAAQPAAAAAAQPS-AVALPAAPAAAAAAAAP---AEAAAPQPTAAKPVV 329
|
250
....*....|..
gi 2245149928 1306 AAIPAASVPTPE 1317
Cdd:COG3266 330 TETAAPAAPAPE 341
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1466-2062 |
1.40e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 51.22 E-value: 1.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1466 LQEALLHCGKFQDALEPLLSWLADTEELIANQKppsaeyKVVKAQIQEQKLLQRLLDDRKATVDMLqaeggriaqSAELA 1545
Cdd:PRK03918 167 LGEVIKEIKRRIERLEKFIKRTENIEELIKEKE------KELEEVLREINEISSELPELREELEKL---------EKEVK 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1546 DREKITGQLESLESRWTELLSKAAARQkqlEDILVLAKQFHETAEPISDfLSVTEKKLANSEPVGTQTAKIQQQIIRHKA 1625
Cdd:PRK03918 232 ELEELKEEIEELEKELESLEGSKRKLE---EKIRELEERIEELKKEIEE-LEEKVKELKELKEKAEEYIKLSEFYEEYLD 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1626 LNEEIVNRKKNVDQAIKNGQALLKQTTG--EEVLLIQEKLDGIKTRYADItvtsSKALRTLEQARQLATKFQSTYEELTG 1703
Cdd:PRK03918 308 ELREIEKRLSRLEEEINGIEERIKELEEkeERLEELKKKLKELEKRLEEL----EERHELYEEAKAKKEELERLKKRLTG 383
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1704 W-LREVEEEL-ATSGGQSPTGEQIPQFQQRQKELKKEVMEHRlvlDTVNEVSRALLElVPWRAREGLDKLVSDANEQYKL 1781
Cdd:PRK03918 384 LtPEKLEKELeELEKAKEEIEEEISKITARIGELKKEIKELK---KAIEELKKAKGK-CPVCGRELTEEHRKELLEEYTA 459
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1782 VSDTIGQRVDEIDAAIQRSQQYEQAADAELAW-------------VAETKRKLMALGPIRLEQDQTTAQLQVQKAFSI-- 1846
Cdd:PRK03918 460 ELKRIEKELKEIEEKERKLRKELRELEKVLKKeseliklkelaeqLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLkg 539
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1847 DIIRHKDSMD---ELFSHRSEIfgtcgEEQKTVLQEKTESLIQQ-----YEAISLLNsERYARLEraqvlvnQFWETYEE 1918
Cdd:PRK03918 540 EIKSLKKELEkleELKKKLAEL-----EKKLDELEEELAELLKEleelgFESVEELE-ERLKELE-------PFYNEYLE 606
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1919 LSPWIEETRALIaqlpspaidhEQLRQQQEEMRQLRESIAEHKPHIDKLLKigpQLKEL----NPEEGEMVEEKYQKAEN 1994
Cdd:PRK03918 607 LKDAEKELEREE----------KELKKLEEELDKAFEELAETEKRLEELRK---ELEELekkySEEEYEELREEYLELSR 673
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 1995 MYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLrmpplipAEVDKIRECISDNK 2062
Cdd:PRK03918 674 ELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKAL-------ERVEELREKVKKYK 734
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
1028-1139 |
1.44e-05 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 50.74 E-value: 1.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1028 SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAvPTP---EEPTSPAA-AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1103
Cdd:PRK06995 52 APPAAAAPAAAQPPPAAAPAAVSRPAAPAAE-PAPwlvEHAKRLTAqREQLVARAAAPAAPEAQAPAAPAERAAAENAAR 130
|
90 100 110
....*....|....*....|....*....|....*.
gi 2245149928 1104 PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPT 1139
Cdd:PRK06995 131 RLARAAAAAPRPRVPADAAAAVADAVKARIERIVND 166
|
|
| KLF9_13_N-like |
cd21975 |
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like ... |
1088-1234 |
1.47e-05 |
|
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like transcription factors (KLFs) belong to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the related N-terminal domains of KLF9, KLF13, KLF14, KLF16, and similar proteins.
Pssm-ID: 409240 [Multi-domain] Cd Length: 163 Bit Score: 48.15 E-value: 1.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1088 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPaaavPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVP--- 1164
Cdd:cd21975 22 RPDPEGAGLAAGLDVRATREVAKGPGPPGPAWK----PDGADSPGLVTAAPHLLAANVLAPLRGPSVEGSSLESGDAdmg 97
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1165 --TPEESASPAAAVPTPAESASFAAvvatleePTSPAASVPTPAAMVatleEFTSPAASVPTSEEPASLAAA 1234
Cdd:cd21975 98 sdSDVAPASGAAASTSPESSSDAAS-------SPSPLSLLHPGEAGL----EPERPRPRVRRGVRRRGVTPA 158
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1503-1832 |
1.49e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.09 E-value: 1.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1503 EYKVVKAQIQEQKLLQRLLDDRKATVDmLQAEGGRIAQSAelADREKITGQLESLESRWTELLSKAAARQKQLEDILVLA 1582
Cdd:COG1196 214 RYRELKEELKELEAELLLLKLRELEAE-LEELEAELEELE--AELEELEAELAELEAELEELRLELEELELELEEAQAEE 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1583 KQFHETAEPISDFLSVTEKKLANSEP----VGTQTAKIQQQIIRHKALNEEIVNRKKNVDQAIKNGQALLKQTTGEEVLL 1658
Cdd:COG1196 291 YELLAELARLEQDIARLEERRRELEErleeLEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1659 IQEKLDGIKTRYADitvtSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELAtsggqsptgEQIPQFQQRQKELKKE 1738
Cdd:COG1196 371 EAELAEAEEELEEL----AEELLEALRAAAELAAQLEELEEAEEALLERLERLEE---------ELEELEEALAELEEEE 437
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1739 VMEHRLVLDTVNEVSRALLELvpwrarEGLDKLVSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETK 1818
Cdd:COG1196 438 EEEEEALEEAAEEEAELEEEE------EALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511
|
330
....*....|....
gi 2245149928 1819 RKLMALGPIRLEQD 1832
Cdd:COG1196 512 AALLLAGLRGLAGA 525
|
|
| PRK10905 |
PRK10905 |
cell division protein DamX; Validated |
1070-1295 |
1.50e-05 |
|
cell division protein DamX; Validated
Pssm-ID: 236792 [Multi-domain] Cd Length: 328 Bit Score: 50.32 E-value: 1.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1070 AAVPTPEEPTSPAAAVPTPEEPT-SPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAP 1148
Cdd:PRK10905 50 GVQPAPGTTSAEQTAGNTQQDVSlPPISSTPTQGQTPVATDGQQRVEVQGDLNNALTQPQNQQQLNNVAVNSTLPTEPAT 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1149 AVPTPEESASAAvavpTPEESASPAAAVPTPAESAsfaAVVatleEPTSPAASVPTPAamvatleeftSPAASVPTSEEP 1228
Cdd:PRK10905 130 VAPVRNGNASRQ----TAKTQTAERPATTRPARKQ---AVI----EPKKPQATAKTEP----------KPVAQTPKRTEP 188
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1229 ASLAAAvsnpeePTSPAAAVPTLEEPTSSAAAVLTPeelsSPAASVPTPEEPASPAAAVSNLEEPAS 1295
Cdd:PRK10905 189 AAPVAS------TKAPAATSTPAPKETATTAPVQTA----SPAQTTATPAAGGKTAGNVGSLKSAPS 245
|
|
| PHA02030 |
PHA02030 |
hypothetical protein |
969-1057 |
1.59e-05 |
|
hypothetical protein
Pssm-ID: 222843 [Multi-domain] Cd Length: 336 Bit Score: 49.98 E-value: 1.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 969 GTPEGPVTPATTVHAPEEPDTAAVrvsTPEEPASPAAAVPTPEEPTSPAA-AVP-TPEEPTSPAAavpPPEEPTSPAAAV 1046
Cdd:PHA02030 249 GGEDLIIKPKSKAAGSNLPAVPNV---AADAGSAAAPAVPAAAAAVAQAApSVPqVPNVAVLPDV---PQVAPVAAPAAP 322
|
90
....*....|.
gi 2245149928 1047 PTPEEPTSPAA 1057
Cdd:PHA02030 323 EVPAVPVVPAA 333
|
|
| PTZ00436 |
PTZ00436 |
60S ribosomal protein L19-like protein; Provisional |
931-1088 |
1.66e-05 |
|
60S ribosomal protein L19-like protein; Provisional
Pssm-ID: 185616 [Multi-domain] Cd Length: 357 Bit Score: 50.33 E-value: 1.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 931 ETAPAVAAAITQEGMSAVAGFSPEWAALAiTVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPeePASPAAAVPTP 1010
Cdd:PTZ00436 191 EDAAAAAAAKQKAAAKKAAAPSGKKSAKA-AAPAKAAAAPAKAAAPPAKAAAAPAKAAAAPAKAAAP--PAKAAAPPAKA 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1011 EEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPA-AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP--EEPTSPAAAVPT 1087
Cdd:PTZ00436 268 AAPPAKAAAPPAKAAAPPAKAAAPPAKAAAAPAkAAAAPAKAAAAPAKAAAPPAKAAAPPAKAATPpaKAAAPPAKAAAA 347
|
.
gi 2245149928 1088 P 1088
Cdd:PTZ00436 348 P 348
|
|
| PTZ00436 |
PTZ00436 |
60S ribosomal protein L19-like protein; Provisional |
977-1101 |
1.67e-05 |
|
60S ribosomal protein L19-like protein; Provisional
Pssm-ID: 185616 [Multi-domain] Cd Length: 357 Bit Score: 50.33 E-value: 1.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 977 PATTVHAPEEPDTAAVRVSTPeePASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPA-AAVPTPEEPTSP 1055
Cdd:PTZ00436 222 PAKAAAAPAKAAAPPAKAAAA--PAKAAAAPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAkAAAPPAKAAAAP 299
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2245149928 1056 AAAVPTP-EEPTSPAAAVPTPEEPTSPAAAVPTP--EEPTSPAAAVPTP 1101
Cdd:PTZ00436 300 AKAAAAPaKAAAAPAKAAAPPAKAAAPPAKAATPpaKAAAPPAKAAAAP 348
|
|
| DUF3729 |
pfam12526 |
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ... |
947-1040 |
1.69e-05 |
|
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.
Pssm-ID: 372164 [Multi-domain] Cd Length: 115 Bit Score: 46.61 E-value: 1.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 947 AVAGFSPEWA---ALAITVPITEEDGTPEGPVTPattvhaPEEPDTAaVRVSTPEEPASPAAAVPTPEEPTSPaaavPTP 1023
Cdd:pfam12526 21 STSGFSSCFSppeSAHPDPPPPVGDPRPPVVDTP------PPVSAVW-VLPPPSEPAAPEPDLVPPVTGPAGP----PSP 89
|
90
....*....|....*...
gi 2245149928 1024 EEPTSPAAAVP-PPEEPT 1040
Cdd:pfam12526 90 LAPPAPAQKPPlPPPRPQ 107
|
|
| LytB |
COG2247 |
Putative cell wall-binding domain (amidase enhancer), LytB superfamily [Cell wall/membrane ... |
979-1191 |
1.78e-05 |
|
Putative cell wall-binding domain (amidase enhancer), LytB superfamily [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441848 [Multi-domain] Cd Length: 472 Bit Score: 50.49 E-value: 1.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 979 TTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAA 1058
Cdd:COG2247 1 AAAAASVLDGGGVTSAAVGSVADAGVTDSTATTSATSVAGGAAAAADPGVAAVVVAVGADTAAAVAAAAVAAATAAAAAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1059 VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP 1138
Cdd:COG2247 81 SAAGVAVDAAAAAAAAAAAAAAASAAAVAAAAGAADAGLLTLLGTDSAAAAGVTVVAAVALTAVVVAVGLGTASATVAAA 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1139 TPEEPAFPAPAVPTPEESASAAVAVPTpeesASPAAAVPTPAESASfAAVVAT 1191
Cdd:COG2247 161 AAGGVGRAAGGRAAAAAAAAAAAAAGG----AAGAVAIAKAGDSAD-TVVLAR 208
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
995-1100 |
1.79e-05 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 50.35 E-value: 1.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 995 STPEEPASPAAAVPTPEEPTSPAAAVPTP---EEPTSPAA-AVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1070
Cdd:PRK06995 57 AAPAAAQPPPAAAPAAVSRPAAPAAEPAPwlvEHAKRLTAqREQLVARAAAPAAPEAQAPAAPAERAAAENAARRLARAA 136
|
90 100 110
....*....|....*....|....*....|
gi 2245149928 1071 AVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1100
Cdd:PRK06995 137 AAAPRPRVPADAAAAVADAVKARIERIVND 166
|
|
| PRK10905 |
PRK10905 |
cell division protein DamX; Validated |
831-1045 |
1.90e-05 |
|
cell division protein DamX; Validated
Pssm-ID: 236792 [Multi-domain] Cd Length: 328 Bit Score: 49.94 E-value: 1.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 831 LQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPeGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVP 910
Cdd:PRK10905 20 LKAPSTSSSDQTASGEKSIDLAGNATDQANGVQPAP-GTTSAEQTAGNTQQDVSLPPISSTPTQGQTPVATDGQQRVEVQ 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 911 -----AVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPitEEDGTPEGPVTPATTVHAPE 985
Cdd:PRK10905 99 gdlnnALTQPQNQQQLNNVAVNSTLPTEPATVAPVRNGNASRQTAKTQTAERPATTRP--ARKQAVIEPKKPQATAKTEP 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 986 EPDTAAVRVStpeEPASPAAavpTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAA 1045
Cdd:PRK10905 177 KPVAQTPKRT---EPAAPVA---STKAPAATSTPAPKETATTAPVQTASPAQTTATPAAG 230
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
1092-1177 |
1.93e-05 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 49.64 E-value: 1.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1092 TSPAAAVPTPEEPTSPAAAVPTPeEPASPAAAVPTPEEPASPAAAV-PTPEEPAFPAPAVPTPEESASAAVAVPTPEESA 1170
Cdd:PRK10856 166 TSTTTDPATTPAPAAPVDTTPTN-SQTPAVATAPAPAVDPQQNAVVaPSQANVDTAATPAPAAPATPDGAAPLPTDQAGV 244
|
....*..
gi 2245149928 1171 SPAAAVP 1177
Cdd:PRK10856 245 STPAADP 251
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
1157-1291 |
2.00e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 50.45 E-value: 2.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1157 ASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAmvatleeftSPAASVPTSEEPASLAAAVS 1236
Cdd:PRK14959 378 ASAPSGSAAEGPASGGAATIPTPGTQGPQGTAPAAGMTPSSAAPATPAPSA---------APSPRVPWDDAPPAPPRSGI 448
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 2245149928 1237 NPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAAsvPTPEEPASPAAAVSNLE 1291
Cdd:PRK14959 449 PPRPAPRMPEASPVPGAPDSVASASDAPPTLGDPSD--TAEHTPSGPRTWDGFLE 501
|
|
| RecN |
COG0497 |
DNA repair ATPase RecN [Replication, recombination and repair]; |
1875-2135 |
2.04e-05 |
|
DNA repair ATPase RecN [Replication, recombination and repair];
Pssm-ID: 440263 [Multi-domain] Cd Length: 555 Bit Score: 50.46 E-value: 2.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1875 TVLQEKTESLIQ---QYEAISLLNSE-------RYARLERaqvLVNQFWETYEELspwieetRALIAQLpspaidhEQLR 1944
Cdd:COG0497 116 SQLRELGELLVDihgQHEHQSLLDPDaqrelldAFAGLEE---LLEEYREAYRAW-------RALKKEL-------EELR 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1945 QQQEEMRQ----LRESIAEhkphidkllkigpqLKELNPEEGEMVE--EKYQKAENmYAQIKEEVrQRAL---------- 2008
Cdd:COG0497 179 ADEAERAReldlLRFQLEE--------------LEAAALQPGEEEEleEERRRLSN-AEKLREAL-QEALealsggegga 242
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2009 --ALDEAVSQSTQITEFHDKIEPMLETLENLSsrlrmpplipAEVDKIRECISDNKSATV----ELEKLQpsfE------ 2076
Cdd:COG0497 243 ldLLGQALRALERLAEYDPSLAELAERLESAL----------IELEEAASELRRYLDSLEfdpeRLEEVE---Erlallr 309
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 2077 ALKRR-G---EELIGRsqgadkdlaAKEIQDKLDQMVFFWEDIKARAEEREIKFLDVLELAEK 2135
Cdd:COG0497 310 RLARKyGvtvEELLAY---------AEELRAELAELENSDERLEELEAELAEAEAELLEAAEK 363
|
|
| PHA01929 |
PHA01929 |
putative scaffolding protein |
1042-1137 |
2.07e-05 |
|
putative scaffolding protein
Pssm-ID: 177328 Cd Length: 306 Bit Score: 49.67 E-value: 2.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1042 PAAAVPTPE-EPTSPAAAVPTPEEPTSPA-AAVPTPEEPTSPAAAVPTPEEPTSPAAavPTPEEPTSPAAAVPTPEEPAS 1119
Cdd:PHA01929 20 PPAAAPTPQpNPVIQPQAPVQPGQPGAPQqLAIPTQQPQPVPTSAMTPHVVQQAPAQ--PAPAAPPAAGAALPEALEVPP 97
|
90
....*....|....*...
gi 2245149928 1120 PAAAVPtPEEPASPAAAV 1137
Cdd:PHA01929 98 PPAFTP-NGEIVGTLAGN 114
|
|
| SAV_2336_NTERM |
NF041121 |
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ... |
977-1064 |
2.14e-05 |
|
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.
Pssm-ID: 469044 [Multi-domain] Cd Length: 473 Bit Score: 50.00 E-value: 2.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 977 PATTVHAPEEPDTAAVRvSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPeePTSPA 1056
Cdd:NF041121 19 AAPPSPEGPAPTAASQP-ATPPPPAAPPSPPGDPPEPPAPEPAPLPAPYPGSLAPPPPPPPGPAGAAPGAALP--VRVPA 95
|
....*....
gi 2245149928 1057 AAV-PTPEE 1064
Cdd:NF041121 96 PPAlPNPLE 104
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
1012-1084 |
2.17e-05 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 50.38 E-value: 2.17e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1012 EPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEeptsPAAA 1084
Cdd:COG5373 36 ELAEAAEAASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEAEPAAA----PAAA 104
|
|
| Gag_spuma |
pfam03276 |
Spumavirus gag protein; |
1002-1138 |
2.19e-05 |
|
Spumavirus gag protein;
Pssm-ID: 460872 [Multi-domain] Cd Length: 614 Bit Score: 50.52 E-value: 2.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1002 SPAAAVPTPeePTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTP---EEPTSPAAAVPtPEEPTSPAAAVPTPEEP 1078
Cdd:pfam03276 187 PPGASFSGL--PSLPAIGGIHLPAIPGIHARAPPGNIARSLGDDIMPSlgdAGMPQPRFAFH-PGNPFAEAEGHPFAEAE 263
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1079 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP 1138
Cdd:pfam03276 264 GERPRDIPRAPRIDAPSAPAIPAIQPIAPPMIPPIGAPIPIPHGASIPGEHIRNPREEPI 323
|
|
| DUF3729 |
pfam12526 |
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ... |
1125-1206 |
2.22e-05 |
|
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.
Pssm-ID: 372164 [Multi-domain] Cd Length: 115 Bit Score: 46.22 E-value: 2.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1125 PTPEEPASPAAAvPTPEEPafPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVAtleePTSPAASVPT 1204
Cdd:pfam12526 29 FSPPESAHPDPP-PPVGDP--RPPVVDTPPPVSAVWVLPPPSEPAAPEPDLVPPVTGPAGPPSPLA----PPAPAQKPPL 101
|
..
gi 2245149928 1205 PA 1206
Cdd:pfam12526 102 PP 103
|
|
| PHA03264 |
PHA03264 |
envelope glycoprotein D; Provisional |
1003-1151 |
2.28e-05 |
|
envelope glycoprotein D; Provisional
Pssm-ID: 223029 [Multi-domain] Cd Length: 416 Bit Score: 50.00 E-value: 2.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1003 PAAAVPTPEEPtSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAA-VPTPEEPTSPAAAVptpeePTSPAAAVPTPeEPTSP 1081
Cdd:PHA03264 256 PYFEESKGYEP-PPAPSGGSPAPPGDDRPEAKPEPGPVEDGAPgRETGGEGEGPEPAG-----RDGAAGGEPKP-GPPRP 328
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1082 AAAVPTPEE-PTSPAAAVPtPEEPTSPAA--AVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVP 1151
Cdd:PHA03264 329 APDADRPEGwPSLEAITFP-PPTPATPAVprARPVIVGTGIAAAAIACVAAAGAVAYFVYTRRRGAGPLPTKE 400
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
1104-1190 |
2.45e-05 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 49.64 E-value: 2.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1104 PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESA 1183
Cdd:PRK10856 163 PLDTSTTTDPATTPAPAAPVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPSQANVDTAATPAPAAPATPDGAAPLPTDQA 242
|
....*..
gi 2245149928 1184 SFAAVVA 1190
Cdd:PRK10856 243 GVSTPAA 249
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
1017-1080 |
2.54e-05 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 49.68 E-value: 2.54e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 1017 AAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1080
Cdd:PTZ00144 120 TGGAPPAAAPAAAAAAKAEKTTPEKPKAAAPTPEPPAASKPTPPAAAKPPEPAPAAKPPPTPVA 183
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
958-1158 |
2.60e-05 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 50.21 E-value: 2.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 958 LAITVpiteeDGTPEGPVTPATTVHAPEEPDTaavrvstPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA---VP 1034
Cdd:PRK14086 84 IAITV-----DPSAGEPAPPPPHARRTSEPEL-------PRPGRRPYEGYGGPRADDRPPGLPRQDQLPTARPAYpayQQ 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1035 PPEEPTSPAAAVPTPEEPTS----PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE-EPTSPAAAVPTPEE---PTS 1106
Cdd:PRK14086 152 RPEPGAWPRAADDYGWQQQRlgfpPRAPYASPASYAPEQERDREPYDAGRPEYDQRRRDyDHPRPDWDRPRRDRtdrPEP 231
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1107 PAAAVPTPEEPASPAAAVPTPEEPASPAAAVPtpeEPAFPAPAVPTPEESAS 1158
Cdd:PRK14086 232 PPGAGHVHRGGPGPPERDDAPVVPIRPSAPGP---LAAQPAPAPGPGEPTAR 280
|
|
| KLF14_N |
cd21576 |
N-terminal domain of Kruppel-like factor 14; Kruppel-like factor 14 (KLF14; also known as ... |
989-1153 |
2.63e-05 |
|
N-terminal domain of Kruppel-like factor 14; Kruppel-like factor 14 (KLF14; also known as Krueppel-like factor 14 or basic transcription element-binding protein 5/BTEB5) is a protein that in humans is encoded by the KLF14 gene. KLF14 regulates the transcription of various genes, including TGFbetaRII (the type II receptor for TGFbeta). KLF14 is expressed in many tissues, lacks introns, and is subject to parent-specific expression. It also appears to be a master regulator of gene expression in adipose tissue. KLF14 is associated with coronary artery disease, hypercholesterolemia, and type 2 diabetes. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. KLF14 belongs to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the N-terminal domain of KLF14.
Pssm-ID: 409238 [Multi-domain] Cd Length: 195 Bit Score: 47.89 E-value: 2.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 989 TAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPtsPAAAVPPPeePTSPAAAVPTPEE-PTSPAAAVPTPEEPTS 1067
Cdd:cd21576 20 AGAVLHRRAPDPEGAGGAAGSEVGAAPPESALPGPGPP--GPAWVPPL--LQVPAPSPGAGGAaPHLLAASVLADLRGGA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1068 PAAAVPTPEEptSPAAAVPTPEePTSPAAAVPTPEE-PTSPAAAVPTPEEpASPAAAVP-TPEEPASPAAAVPTPEEP-- 1143
Cdd:cd21576 96 GEGSREDSGE--APRASSGSSD-PARGSSPTLGSEPaPASGEDAVSGPES-SFGAPAIPsAPAAPGAPAVSGEVPGGApg 171
|
170
....*....|.
gi 2245149928 1144 AFPAPAV-PTP 1153
Cdd:cd21576 172 AGPAPAAgPAP 182
|
|
| PTZ00441 |
PTZ00441 |
sporozoite surface protein 2 (SSP2); Provisional |
1034-1179 |
2.66e-05 |
|
sporozoite surface protein 2 (SSP2); Provisional
Pssm-ID: 240420 [Multi-domain] Cd Length: 576 Bit Score: 49.96 E-value: 2.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1034 PPPEEPTS-PAAAVPTPEE----PTSPAAAVPTPEE----PTSPAAAVPTPEE-----PTS----PAAAVPTPEEPTSPa 1095
Cdd:PTZ00441 283 PVEPEPLPvPAPVPPTPEDdnprPTDDEFAVPNFNEgldvPDNPQDPVPPPNEgkdgnPNEenlfPPGDDEVPDESNVP- 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1096 aavptPEEPTSPAAavpTPEEPASPAAAVPTPEEPASPAAA--VPTPEEPAFPAPAVPTPEESASAAVAVPTPEESAS-- 1171
Cdd:PTZ00441 362 -----PNPPNVPGG---SNSEFSSDVENPPNPPNPDIPEQEpnIPEDSNKEVPEDVPMEPEDDRDNNFNEPKKPENKGdg 433
|
....*....
gi 2245149928 1172 -PAAAVPTP 1179
Cdd:PTZ00441 434 qNEPVIPKP 442
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
1138-1314 |
2.67e-05 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 49.38 E-value: 2.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1138 PTPEEPAFPAPAVPTPEESASAAVavptPEESASPAAAVPTPAEsasfaavvatleeptsPAASVPTPAAMVATLEEFTS 1217
Cdd:NF040712 190 PDFGRPLRPLATVPRLAREPADAR----PEEVEPAPAAEGAPAT----------------DSDPAEAGTPDDLASARRRR 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1218 PAASVPTSEEPASLAAavsnpeEPTSPAAAVPTLEEPTSSAAAVLTPEElsSPAASVPTPEEPASPAAAvsnlEEPASPA 1297
Cdd:NF040712 250 AGVEQPEDEPVGPGAA------PAAEPDEATRDAGEPPAPGAAETPEAA--EPPAPAPAAPAAPAAPEA----EEPARPE 317
|
170
....*....|....*..
gi 2245149928 1298 AAVPTPEVAAIPAASVP 1314
Cdd:NF040712 318 PPPAPKPKRRRRRASVP 334
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
1056-1178 |
2.67e-05 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 49.96 E-value: 2.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1056 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEeptSPAAAVPTPEEPTSPAAAvPTPEEPASPAAAVPTPEEPASPAA 1135
Cdd:PRK06995 49 AALAPPAAAAPAAAQPPPAAAPAAVSRPAAPAAE---PAPWLVEHAKRLTAQREQ-LVARAAAPAAPEAQAPAAPAERAA 124
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 2245149928 1136 AVPTPEEPAFPAPAVPTPEESASAAvAVPTPEESASPAAAVPT 1178
Cdd:PRK06995 125 AENAARRLARAAAAAPRPRVPADAA-AAVADAVKARIERIVND 166
|
|
| rad23 |
TIGR00601 |
UV excision repair protein Rad23; All proteins in this family for which functions are known ... |
989-1135 |
2.74e-05 |
|
UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273167 [Multi-domain] Cd Length: 378 Bit Score: 49.51 E-value: 2.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 989 TAAVRVSTPEEPASPAAAvPTPEePTSPAAAVPTPEEPtsPAAAVPPPEEPT-SPAAAVPTPEEPTSPAAAVPTPEEPTS 1067
Cdd:TIGR00601 77 PKTGTGKVAPPAATPTSA-PTPT-PSPPASPASGMSAA--PASAVEEKSPSEeSATATAPESPSTSVPSSGSDAASTLVV 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1068 PAAAVPTPEEPTSPA-----------AAVPTPEE---------PTSPAAAVPTPEEPTSPAAA-VPTPEEPA-SPAAAVP 1125
Cdd:TIGR00601 153 GSERETTIEEIMEMGyereeveralrAAFNNPDRaveylltgiPEDPEQPEPVQQTAASTAAAtTETPQHGSvFEQAAQG 232
|
170
....*....|
gi 2245149928 1126 TPEEPASPAA 1135
Cdd:TIGR00601 233 GTEQPATEAA 242
|
|
| PHA03264 |
PHA03264 |
envelope glycoprotein D; Provisional |
1055-1199 |
2.79e-05 |
|
envelope glycoprotein D; Provisional
Pssm-ID: 223029 [Multi-domain] Cd Length: 416 Bit Score: 49.62 E-value: 2.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1055 PAAAVPTPEEPtSPAAAVPTPEEPTSPAAAvPTPEE-PTSPAAA-VPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPAS 1132
Cdd:PHA03264 256 PYFEESKGYEP-PPAPSGGSPAPPGDDRPE-AKPEPgPVEDGAPgRETGGEGEGPEPAGRDGAAGGEPKPGPPRPAPDAD 333
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1133 PAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTpeesASPAAAVPTPAESASFAAVVATLEEPTSPA 1199
Cdd:PHA03264 334 RPEGWPSLEAITFPPPTPATPAVPRARPVIVGT----GIAAAAIACVAAAGAVAYFVYTRRRGAGPL 396
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
1151-1338 |
2.97e-05 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 50.08 E-value: 2.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1151 PTPEESASAAVAVPTPEESASPAAAVptpAESASFAAVVATLEEPT---SPAASVPTPAAMVATLEEFTSPAasvPTSEE 1227
Cdd:PRK10263 315 PITEPVAVAAAATTATQSWAAPVEPV---TQTPPVASVDVPPAQPTvawQPVPGPQTGEPVIAPAPEGYPQQ---SQYAQ 388
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1228 PASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEP-------ASPAAAV 1300
Cdd:PRK10263 389 PAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQStfapqstYQTEQTY 468
|
170 180 190
....*....|....*....|....*....|....*...
gi 2245149928 1301 PTPeVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVP 1338
Cdd:PRK10263 469 QQP-AAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPP 505
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
1065-1194 |
3.17e-05 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 49.58 E-value: 3.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1065 PTSPAAAVPTPEEPTSPAAAVPTPEEPTsPAAAVPTPEEPTSPAAAVptpEEPASPAAAVPTPEEPASPAAAVPTPEEPa 1144
Cdd:PRK06995 53 PPAAAAPAAAQPPPAAAPAAVSRPAAPA-AEPAPWLVEHAKRLTAQR---EQLVARAAAPAAPEAQAPAAPAERAAAEN- 127
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1145 fpaPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEE 1194
Cdd:PRK06995 128 ---AARRLARAAAAAPRPRVPADAAAAVADAVKARIERIVNDTVMQELRS 174
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
1105-1190 |
3.30e-05 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 48.87 E-value: 3.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1105 TSPAAAVPTPEEPASPAAAVPTPeEPASPAAAVPTPEEPA-FPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESA 1183
Cdd:PRK10856 166 TSTTTDPATTPAPAAPVDTTPTN-SQTPAVATAPAPAVDPqQNAVVAPSQANVDTAATPAPAAPATPDGAAPLPTDQAGV 244
|
....*..
gi 2245149928 1184 SFAAVVA 1190
Cdd:PRK10856 245 STPAADP 251
|
|
| PLN02983 |
PLN02983 |
biotin carboxyl carrier protein of acetyl-CoA carboxylase |
1004-1160 |
3.56e-05 |
|
biotin carboxyl carrier protein of acetyl-CoA carboxylase
Pssm-ID: 215533 [Multi-domain] Cd Length: 274 Bit Score: 48.68 E-value: 3.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1004 AAAVPTPeePTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAA-----AVPTPEEPTSPAAAVPTPEEP 1078
Cdd:PLN02983 1 MASLSVP--CAKTAAAAANVGSRLSRSSFRLQPKPNISFPSKGPNPKRSAVPKVkaqlnEVAVDGSSNSAKSDDPKSEVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1079 TSPAAAVPTPEEPTSPAaaVPTPEE----------------------------------------PTSPAAAVPTPEEPA 1118
Cdd:PLN02983 79 PSEPKDEPPSNSSSKPN--LPDEESisefmtqvsslvklvdsrdivelqlkqldcelvirkkealPQPPPPAPVVMMQPP 156
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2245149928 1119 SPAAAVPTPEEPASPAAAVPTPEEPafPAPAVPTPEESASAA 1160
Cdd:PLN02983 157 PPHAMPPASPPAAQPAPSAPASSPP--PTPASPPPAKAPKSS 196
|
|
| PHA03377 |
PHA03377 |
EBNA-3C; Provisional |
1026-1342 |
3.59e-05 |
|
EBNA-3C; Provisional
Pssm-ID: 177614 [Multi-domain] Cd Length: 1000 Bit Score: 50.05 E-value: 3.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1026 PTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAA--AVPTPEEPtSPAAAVPTPEEPtspaaAVPTPEEPTSPAAAVPTPEE 1103
Cdd:PHA03377 412 PWRKPRTLPWPTPKTHPVKRTLVKTSGRSDEAeqAQSTPERP-GPSDQPSVPVEP-----AHLTPVEHTTVILHQPPQSP 485
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1104 PTSPAaavptpeEPASPAAAVP------TPEEPASPAAAVPTPEEPAFPAPAVP----------TPEESASAAVAVPTPE 1167
Cdd:PHA03377 486 PTVAI-------KPAPPPSRRRrgacvvYDDDIIEVIDVETTEEEESVTQPAKPhrkvqdgfqrSGRRQKRATPPKVSPS 558
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1168 ESASPAAAVPTPAESASFAAVVATleEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNP--------- 1238
Cdd:PHA03377 559 DRGPPKASPPVMAPPSTGPRVMAT--PSTGPRDMAPPSTGPRQQAKCKDGPPASGPHEKQPPSSAPRDMAPsvvrmflre 636
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1239 ---EEPTSPAA-----------AVPTLEEPTSSAAAVLTPEE-----------LSSPAASVPTPEE-----PASPAAAVS 1288
Cdd:PHA03377 637 rllEQSTGPKPksfwemragrdGSGIQQEPSSRRQPATQSTPprpswlpsvfvLPSVDAGRAQPSEeshlsSMSPTQPIS 716
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2245149928 1289 NLEEPASPAAAVPT-----PEVAAIPAASVPTP--EVPAIPAAAVPPMEEVSPIGVPFLGV 1342
Cdd:PHA03377 717 HEEQPRYEDPDDPLdlslhPDQAPPPSHQAPYSghEEPQAQQAPYPGYWEPRPPQAPYLGY 777
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
1082-1143 |
3.59e-05 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 49.30 E-value: 3.59e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1082 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEP 1143
Cdd:PTZ00144 120 TGGAPPAAAPAAAAAAKAEKTTPEKPKAAAPTPEPPAASKPTPPAAAKPPEPAPAAKPPPTP 181
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
996-1054 |
3.59e-05 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 49.30 E-value: 3.59e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 996 TPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTS 1054
Cdd:PTZ00144 125 PAAAPAAAAAAKAEKTTPEKPKAAAPTPEPPAASKPTPPAAAKPPEPAPAAKPPPTPVA 183
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
986-1058 |
3.77e-05 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 49.61 E-value: 3.77e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 986 EPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEeptsPAAA 1058
Cdd:COG5373 36 ELAEAAEAASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEAEPAAA----PAAA 104
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
1028-1107 |
3.92e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 49.58 E-value: 3.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1028 SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAvPTPEEPTSP 1107
Cdd:PRK14948 518 SNTAKTPPPPQKSPPPPAPTPPLPQPTATAPPPTPPPPPPTATQASSNAPAQIPADSSPPPPIPEEPTPS-PTKDSSPEE 596
|
|
| PHA03264 |
PHA03264 |
envelope glycoprotein D; Provisional |
1016-1173 |
4.04e-05 |
|
envelope glycoprotein D; Provisional
Pssm-ID: 223029 [Multi-domain] Cd Length: 416 Bit Score: 49.23 E-value: 4.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1016 PAAAVPTP-EEPTSPAAAVP-PPEEPTSPAAAVPTPEEPTSPAAAvpTPEEPTSPAAAVptpeePTSPAAAVPTPeEPTS 1093
Cdd:PHA03264 256 PYFEESKGyEPPPAPSGGSPaPPGDDRPEAKPEPGPVEDGAPGRE--TGGEGEGPEPAG-----RDGAAGGEPKP-GPPR 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1094 PAAAVPTPEE-PTSPAAAVPtPEEPASPAaavptpeepasPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASP 1172
Cdd:PHA03264 328 PAPDADRPEGwPSLEAITFP-PPTPATPA-----------VPRARPVIVGTGIAAAAIACVAAAGAVAYFVYTRRRGAGP 395
|
.
gi 2245149928 1173 A 1173
Cdd:PHA03264 396 L 396
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
1043-1106 |
4.05e-05 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 49.30 E-value: 4.05e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 1043 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1106
Cdd:PTZ00144 120 TGGAPPAAAPAAAAAAKAEKTTPEKPKAAAPTPEPPAASKPTPPAAAKPPEPAPAAKPPPTPVA 183
|
|
| PTZ00436 |
PTZ00436 |
60S ribosomal protein L19-like protein; Provisional |
918-1075 |
4.14e-05 |
|
60S ribosomal protein L19-like protein; Provisional
Pssm-ID: 185616 [Multi-domain] Cd Length: 357 Bit Score: 48.79 E-value: 4.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 918 EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTP 997
Cdd:PTZ00436 191 EDAAAAAAAKQKAAAKKAAAPSGKKSAKAAAPAKAAAAPAKAAAPPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAAAP 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 998 eePASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTP--EEPTSPAAAVPTP 1075
Cdd:PTZ00436 271 --PAKAAAPPAKAAAPPAKAAAPPAKAAAAPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAATPpaKAAAPPAKAAAAP 348
|
|
| DUF3729 |
pfam12526 |
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ... |
983-1062 |
4.24e-05 |
|
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.
Pssm-ID: 372164 [Multi-domain] Cd Length: 115 Bit Score: 45.45 E-value: 4.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 983 APEEPDTAAVRvSTPEEPASPAAAVPTPEEPTSPAAavPTPEEPTSPAAAVPPPEEPTSPaaavPTPEEPTSPAAAVPTP 1062
Cdd:pfam12526 30 SPPESAHPDPP-PPVGDPRPPVVDTPPPVSAVWVLP--PPSEPAAPEPDLVPPVTGPAGP----PSPLAPPAPAQKPPLP 102
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
973-1094 |
5.09e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 49.29 E-value: 5.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 973 GPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEptSPAAAVP----PPEEPTSPAAAVPT 1048
Cdd:PRK14959 376 GGASAPSGSAAEGPASGGAATIPTPGTQGPQGTAPAAGMTPSSAAPATPAPSA--APSPRVPwddaPPAPPRSGIPPRPA 453
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 2245149928 1049 PEEPtspaAAVPTPEEPTSPAAAVPTPeePTSPAAAVPTPEEPTSP 1094
Cdd:PRK14959 454 PRMP----EASPVPGAPDSVASASDAP--PTLGDPSDTAEHTPSGP 493
|
|
| PRK04654 |
PRK04654 |
sec-independent translocase; Provisional |
989-1099 |
5.12e-05 |
|
sec-independent translocase; Provisional
Pssm-ID: 135173 [Multi-domain] Cd Length: 214 Bit Score: 47.50 E-value: 5.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 989 TAAVRVSTPEEPA----SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAvpTPEE 1064
Cdd:PRK04654 103 TSATPVATPLELAhadlSASAQVDAAAGAEPGAGQAHTPVPAPAPVIAQAQPIAPAPHQTLVPAPHDTIVPAPH--AAHL 180
|
90 100 110
....*....|....*....|....*....|....*.
gi 2245149928 1065 PTSPAAAVPT-PEEPTSPAAavPTPEEPTSPAAAVP 1099
Cdd:PRK04654 181 PSAPATPVSVaPVDAGTSAS--PTPSEPTKIQEKQP 214
|
|
| PHA02030 |
PHA02030 |
hypothetical protein |
1078-1151 |
5.33e-05 |
|
hypothetical protein
Pssm-ID: 222843 [Multi-domain] Cd Length: 336 Bit Score: 48.44 E-value: 5.33e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1078 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA-AVP-TPEEPASPaaAVPTPEEPASPAAavptPEEPAFPA-PAVP 1151
Cdd:PHA02030 264 SNLPAVPNVAADAGSAAAPAVPAAAAAVAQAApSVPqVPNVAVLP--DVPQVAPVAAPAA----PEVPAVPVvPAAP 334
|
|
| PRK15313 |
PRK15313 |
intestinal colonization autotransporter adhesin MisL; |
1088-1161 |
5.51e-05 |
|
intestinal colonization autotransporter adhesin MisL;
Pssm-ID: 237940 [Multi-domain] Cd Length: 955 Bit Score: 49.41 E-value: 5.51e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 1088 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPtpeEPASPAAAVPTPEEPAFPAPAVPTPEESASAAV 1161
Cdd:PRK15313 560 PDEPIIPDPVDPVIPDPVIPDPVDPDPVDPVIPDPVIP---DPVDPDPVDPEPVDPVIPDPTIPDIGQSDTPPI 630
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
985-1050 |
5.51e-05 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 49.23 E-value: 5.51e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 985 EEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPA--AAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPE 1050
Cdd:COG5373 38 AEAAEAASAPAEPEPEAAAAATAAAPEAAPAPVpeAPAAPPAAAEAPAPAAAAPPAEAEPAAAPAAAS 105
|
|
| rad23 |
TIGR00601 |
UV excision repair protein Rad23; All proteins in this family for which functions are known ... |
985-1147 |
5.53e-05 |
|
UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273167 [Multi-domain] Cd Length: 378 Bit Score: 48.74 E-value: 5.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 985 EEPDTAAVRVSTPEepASPAAAVPTPEEPTSPAAAVPTPEeptspaaAVPPPEEPTSPAAAVPtPEEPTSPAAAVPTpee 1064
Cdd:TIGR00601 65 KEKDFVVVMVSKPK--TGTGKVAPPAATPTSAPTPTPSPP-------ASPASGMSAAPASAVE-EKSPSEESATATA--- 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1065 PTSPAAAVPTPEEPTSPAAAVPTPEEPT----------------SPAAAVPTPEE---------PTSPAAAVPTPEEPAS 1119
Cdd:TIGR00601 132 PESPSTSVPSSGSDAASTLVVGSERETTieeimemgyereeverALRAAFNNPDRaveylltgiPEDPEQPEPVQQTAAS 211
|
170 180 190
....*....|....*....|....*....|
gi 2245149928 1120 PAAA-VPTPEEPA-SPAAAVPTPEEPAFPA 1147
Cdd:TIGR00601 212 TAAAtTETPQHGSvFEQAAQGGTEQPATEA 241
|
|
| DUF3432 |
pfam11914 |
Domain of unknown function (DUF3432); This presumed domain is functionally uncharacterized. ... |
1116-1207 |
5.97e-05 |
|
Domain of unknown function (DUF3432); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is about 100 amino acids in length. This domain is found associated with pfam00096. This domain has two conserved sequence motifs: YPSPV and PSP.
Pssm-ID: 403204 [Multi-domain] Cd Length: 98 Bit Score: 44.71 E-value: 5.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1116 EPASPAAAV-PTPEEPASPAAAVPTPEEPAFPAPaVPTPEESasaavavPTPEESASPA-AAVPTPAESASFAAVVATLe 1193
Cdd:pfam11914 1 EKVAPASAVsSISSYSSSVTTSYPSPITTSYPSP-VSTSYSS-------PVPSSYPSPVhTSFPSPSIATTYPSVTTTF- 71
|
90
....*....|....
gi 2245149928 1194 ePTSPAASVPTPAA 1207
Cdd:pfam11914 72 -QTQVASSFPSSVV 84
|
|
| PHA03269 |
PHA03269 |
envelope glycoprotein C; Provisional |
1188-1316 |
6.06e-05 |
|
envelope glycoprotein C; Provisional
Pssm-ID: 165527 [Multi-domain] Cd Length: 566 Bit Score: 48.96 E-value: 6.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1188 VVATLEEPTSPAASVPTPaamVATLEEFTSPAASVPtSEEPASLAAAVSNPE---EPTSPAAAVPTLEE-PTSSAAAVLT 1263
Cdd:PHA03269 8 LIITIACINLIIANLNTN---IPIPELHTSAATQKP-DPAPAPHQAASRAPDpavAPTSAASRKPDLAQaPTPAASEKFD 83
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 1264 PEELSSPAASVpTPEEPASPAAAVSNLEEPASPAAAVPT----PEVAAIPAAS-VPTP 1316
Cdd:PHA03269 84 PAPAPHQAASR-APDPAVAPQLAAAPKPDAAEAFTSAAQaheaPADAGTSAASkKPDP 140
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1111-1365 |
6.84e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.17 E-value: 6.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1111 VPTPEEPASPAA----------AVPT--PEEPASP---AAAVPTPEEPAFPAPA-VPTPEESASAAVAVPTPEESASPAA 1174
Cdd:PHA03247 205 VPSGPGPAAPADltaaalhlygASETylQDEPFVErrvVISHPLRGDIAAPAPPpVVGEGADRAPETARGATGPPPPPEA 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1175 AVPTPAESASFAAVVATLE--EPTSPAASVPTPAAMVATLEEftspaasvpTSEEPASLAAAVSNPEEPTSPAAAVPTLE 1252
Cdd:PHA03247 285 AAPNGAAAPPDGVWGAALAgaPLALPAPPDPPPPAPAGDAEE---------EDDEDGAMEVVSPLPRPRQHYPLGFPKRR 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1253 EPT---SSAAAVLTPEELSSPAASVPT-----PEEPASPAAAVSNLEEPASPAAAVPtpevaaipaASVPTPEVPAIPAA 1324
Cdd:PHA03247 356 RPTwtpPSSLEDLSAGRHHPKRASLPTrkrrsARHAATPFARGPGGDDQTRPAAPVP---------ASVPTPAPTPVPAS 426
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 2245149928 1325 AVPPMEEVSPIGVPflgvsAHTDSVPISEEGTPVLEEASST 1365
Cdd:PHA03247 427 APPPPATPLPSAEP-----GSDDGPAPPPERQPPAPATEPA 462
|
|
| SAV_2336_NTERM |
NF041121 |
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ... |
1079-1181 |
7.23e-05 |
|
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.
Pssm-ID: 469044 [Multi-domain] Cd Length: 473 Bit Score: 48.46 E-value: 7.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1079 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPAspaaavPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESAS 1158
Cdd:NF041121 15 MGRAAAPPSPEGPAPTAASQPATPPPPAAPPSPPGDPPEP------PAPEPAPLPAPYPGSLAPPPPPPPGPAGAAPGAA 88
|
90 100
....*....|....*....|...
gi 2245149928 1159 AAVAVPTPeesaspaAAVPTPAE 1181
Cdd:NF041121 89 LPVRVPAP-------PALPNPLE 104
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
1462-2107 |
7.27e-05 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 49.18 E-value: 7.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1462 RIAQLQEALLHCGK---FQDALEPLLSWLADTEELIANQKPPSAEYKVVKAQIQEQ-KLLQRLLDDRKATVDMLQAEGGR 1537
Cdd:COG3096 335 HLNLVQTALRQQEKierYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEvDSLKSQLADYQQALDVQQTRAIQ 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1538 IAQSaeladrekitgqLESLEsRWTELLSKAAARQKQLEDILvlaKQFHETAEPISDFLSVTEKKLANSEPVGTQTAKIQ 1617
Cdd:COG3096 415 YQQA------------VQALE-KARALCGLPDLTPENAEDYL---AAFRAKEQQATEEVLELEQKLSVADAARRQFEKAY 478
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1618 QQIirhKALNEEiVNRkknvDQAIKNGQALLKQTTGEEVLLiqEKLDGIKTRYADItvtsSKALRTLEQARQLATKFQ-- 1695
Cdd:COG3096 479 ELV---CKIAGE-VER----SQAWQTARELLRRYRSQQALA--QRLQQLRAQLAEL----EQRLRQQQNAERLLEEFCqr 544
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1696 -----STYEELTGWLREVEEELAT-SGGQSPTGEQIPQFQQRQKELKKEVMEHRlvldtvnevSRALLelvpWR-AREGL 1768
Cdd:COG3096 545 igqqlDAAEELEELLAELEAQLEElEEQAAEAVEQRSELRQQLEQLRARIKELA---------ARAPA----WLaAQDAL 611
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1769 DKL-------VSDANE-------------QYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAET-KRKLMA---- 1823
Cdd:COG3096 612 ERLreqsgeaLADSQEvtaamqqllererEATVERDELAARKQALESQIERLSQPGGAEDPRLLALAERlGGVLLSeiyd 691
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1824 -------------LGPIR---LEQDQTTAQLQVQK----------------AFSiDIIRHKDSMDEL-----------FS 1860
Cdd:COG3096 692 dvtledapyfsalYGPARhaiVVPDLSAVKEQLAGledcpedlyliegdpdSFD-DSVFDAEELEDAvvvklsdrqwrYS 770
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1861 HRSEI--FGTCGEEQK-TVLQEKTESLIQQY----------------------------------EAISLLNSERY---A 1900
Cdd:COG3096 771 RFPEVplFGRAAREKRlEELRAERDELAEQYakasfdvqklqrlhqafsqfvgghlavafapdpeAELAALRQRRSeleR 850
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1901 RLERAQVLVNQFWETYEELSPWIEETRALIAQLPSPAIDH-----EQLRQQQEEMRQLRESIAEHKPHIDKLLKIGPQLK 1975
Cdd:COG3096 851 ELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQANLLADETladrlEELREELDAAQEAQAFIQQHGKALAQLEPLVAVLQ 930
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1976 ElNPEEGEMVEEKYQKAENMYAQIK------EEVRQR--ALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRmppli 2047
Cdd:COG3096 931 S-DPEQFEQLQADYLQAKEQQRRLKqqifalSEVVQRrpHFSYEDAVGLLGENSDLNEKLRARLEQAEEARREAR----- 1004
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 2048 paevDKIRECISDNKSATVELEKLQPSFEA-------LKRRGEELiGRSQGADKDLAAKEIQDKLDQ 2107
Cdd:COG3096 1005 ----EQLRQAQAQYSQYNQVLASLKSSRDAkqqtlqeLEQELEEL-GVQADAEAEERARIRRDELHE 1066
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
1041-1165 |
7.28e-05 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 48.42 E-value: 7.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1041 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAvPTPEEpTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAavptpeePASP 1120
Cdd:PRK06995 52 APPAAAAPAAAQPPPAAAPAAVSRPAAPAAE-PAPWL-VEHAKRLTAQREQLVARAAAPAAPEAQAPAA-------PAER 122
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 2245149928 1121 AAAVPTPEEPASPAAAVPTPEEPAfPAPAVPTPEESASAAVAVPT 1165
Cdd:PRK06995 123 AAAENAARRLARAAAAAPRPRVPA-DAAAAVADAVKARIERIVND 166
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
1027-1094 |
7.28e-05 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 48.14 E-value: 7.28e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 1027 TSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1094
Cdd:PTZ00144 120 TGGAPPAAAPAAAAAAKAEKTTPEKPKAAAPTPEPPAASKPTPPAAAKPPEPAPAAKPPPTPVARADP 187
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
999-1063 |
7.60e-05 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 48.84 E-value: 7.60e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2245149928 999 EPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1063
Cdd:COG5373 41 AEAASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEAEPAAAPAAAS 105
|
|
| PRK11633 |
PRK11633 |
cell division protein DedD; Provisional |
1085-1189 |
7.60e-05 |
|
cell division protein DedD; Provisional
Pssm-ID: 236940 [Multi-domain] Cd Length: 226 Bit Score: 46.92 E-value: 7.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1085 VPTP---EEPTS-PAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAA 1160
Cdd:PRK11633 44 VPKPgdrDEPDMmPAATQALPTQPPEGAAEAVRAGDAAAPSLDPATVAPPNTPVEPEPAPVEPPKPKPVEKPKPKPKPQQ 123
|
90 100
....*....|....*....|....*....
gi 2245149928 1161 VAVPTPEESASPAAAVPTPAESASFAAVV 1189
Cdd:PRK11633 124 KVEAPPAPKPEPKPVVEEKAAPTGKAYVV 152
|
|
| PRK11633 |
PRK11633 |
cell division protein DedD; Provisional |
1072-1173 |
7.74e-05 |
|
cell division protein DedD; Provisional
Pssm-ID: 236940 [Multi-domain] Cd Length: 226 Bit Score: 46.92 E-value: 7.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1072 VPTP---EEPTS-PAAAVPTPEEPTSPAAavptpEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPA 1147
Cdd:PRK11633 44 VPKPgdrDEPDMmPAATQALPTQPPEGAA-----EAVRAGDAAAPSLDPATVAPPNTPVEPEPAPVEPPKPKPVEKPKPK 118
|
90 100
....*....|....*....|....*.
gi 2245149928 1148 PAVPTPEESASAAVAVPTPEESASPA 1173
Cdd:PRK11633 119 PKPQQKVEAPPAPKPEPKPVVEEKAA 144
|
|
| rad23 |
TIGR00601 |
UV excision repair protein Rad23; All proteins in this family for which functions are known ... |
1077-1246 |
7.75e-05 |
|
UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273167 [Multi-domain] Cd Length: 378 Bit Score: 47.97 E-value: 7.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1077 EPTSPAAAVPTPEePTSPAAAVPTPeeptSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPeepafPAPAVPTPEES 1156
Cdd:TIGR00601 76 KPKTGTGKVAPPA-ATPTSAPTPTP----SPPASPASGMSAAPASAVEEKSPSEESATATAPES-----PSTSVPSSGSD 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1157 ASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPA----ASVPTPAAMVATLEEFTSPAASVPTSE-EPASL 1231
Cdd:TIGR00601 146 AASTLVVGSERETTIEEIMEMGYEREEVERALRAAFNNPDRAVeyllTGIPEDPEQPEPVQQTAASTAAATTETpQHGSV 225
|
170
....*....|....*..
gi 2245149928 1232 --AAAVSNPEEPTSPAA 1246
Cdd:TIGR00601 226 feQAAQGGTEQPATEAA 242
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
991-1307 |
7.80e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 49.01 E-value: 7.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 991 AVRVSTPEEPASPAAAVPTPEEPTsPAAAVPTPEEPTSPAA----------------------AVPPPEEPTS---PAAA 1045
Cdd:PHA03307 602 AYPENAADTGAGAAAPAPAAPRPD-AAAAGGASARPLRELAdacvlacravleallegpdglsAVPGLAFPRPacpPRAL 680
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1046 VPTPEEPTSPAA-------AVPTPEEPTSPAAAVpTPEEPTSPAAAVPTPEEPTSPAAAVpTPEEPTSPAAAVPTPEEPA 1118
Cdd:PHA03307 681 EACPARLESWLRelrdlrdAVYLARLRGDLPVAG-GREERVAAVRAVSLVARTVAPLVRY-SPRRARARASAWDITDALF 758
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1119 SPAAAVPTpeePASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSP 1198
Cdd:PHA03307 759 SNPSLVPA---KLAEALALLEPAEPQRGAGSSPPVRAEAAFRRPGRLRRSGPAADAASRTASKRKSRSHTPDGGSESSGP 835
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1199 A---ASVPTPAAMVATLEEFTSPAASVP-----------TSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTP 1264
Cdd:PHA03307 836 ArppGAAARPPPARSSESSKSKPAAAGGrargkngrrrpRPPEPRARPGAAAPPKAAAAAPPAGAPAPRPRPAPRVKLGP 915
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1265 EELSSPAAS-----VP--TPEEPASPAAAVsnleepaspaAAVPTPEVAA 1307
Cdd:PHA03307 916 MPPGGPDPRggfrrVPpgDLHTPAPSAAAL----------AAYCPPEVVA 955
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
1015-1094 |
7.87e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 48.42 E-value: 7.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1015 SPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAvPTPEEPTSP 1094
Cdd:PRK14948 518 SNTAKTPPPPQKSPPPPAPTPPLPQPTATAPPPTPPPPPPTATQASSNAPAQIPADSSPPPPIPEEPTPS-PTKDSSPEE 596
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1659-2160 |
8.09e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 48.61 E-value: 8.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1659 IQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELATSggqsptgeqipqfQQRQKELKKE 1738
Cdd:COG4717 51 LEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEEL-------------EAELEELREE 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1739 VMEHRLVLDTVNevsrallelvPWRAREGLDKLVSDaneqyklvsdtIGQRVDEIDAAIQRSQQYEQAADAELAWVAETK 1818
Cdd:COG4717 118 LEKLEKLLQLLP----------LYQELEALEAELAE-----------LPERLEELEERLEELRELEEELEELEAELAELQ 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1819 RKLMALgpirLEQDQTTAQLQVQKAfsidiirhKDSMDELFSHRSEIfgtcgEEQKTVLQEKTESLIQQYEAIS--LLNS 1896
Cdd:COG4717 177 EELEEL----LEQLSLATEEELQDL--------AEELEELQQRLAEL-----EEELEEAQEELEELEEELEQLEneLEAA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1897 ERYARLERAQVLVNQF---------WETYEELSPWIEETRALIAQLPSPAI-----DHEQLRQQQEEMRQLRESIAEHKP 1962
Cdd:COG4717 240 ALEERLKEARLLLLIAaallallglGGSLLSLILTIAGVLFLVLGLLALLFlllarEKASLGKEAEELQALPALEELEEE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1963 HIDKLLKIGPQLKELNPEEGEMVEEKYQKAENMYAQIKEEVRQRALALDE-------AVSQSTQITEF------HDKIEP 2029
Cdd:COG4717 320 ELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEqeiaallAEAGVEDEEELraaleqAEEYQE 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2030 MLETLENLSSRLR-MPPLIPAEVDKIrecisDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQm 2108
Cdd:COG4717 400 LKEELEELEEQLEeLLGELEELLEAL-----DEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAE- 473
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 2109 vffwedikARAEEREIKflDVLELAEKFWYDMAALLTTIKDTQDIVHDLESP 2160
Cdd:COG4717 474 --------LLQELEELK--AELRELAEEWAALKLALELLEEAREEYREERLP 515
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
1584-1689 |
8.59e-05 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 44.23 E-value: 8.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1584 QFHETAEPISDFLSVTEKKLAnSEPVGTQTAKIQQQIIRHKALNEEIVNRKKNVDQAIKNGQALLkQTTGEEVLLIQEKL 1663
Cdd:pfam00435 5 QFFRDADDLESWIEEKEALLS-SEDYGKDLESVQALLKKHKALEAELAAHQDRVEALNELAEKLI-DEGHYASEEIQERL 82
|
90 100
....*....|....*....|....*.
gi 2245149928 1664 DGIKTRYaditvtssKALRTLEQARQ 1689
Cdd:pfam00435 83 EELNERW--------EQLLELAAERK 100
|
|
| PHA03169 |
PHA03169 |
hypothetical protein; Provisional |
998-1153 |
8.85e-05 |
|
hypothetical protein; Provisional
Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 48.04 E-value: 8.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 998 EEPASPAAAVPTPEEPTSPAAAvpTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAaavptPEEPTSPAAAVPTPEE 1077
Cdd:PHA03169 102 SPTPSPSGSAEELASGLSPENT--SGSSPESPASHSPPPSPPSHPGPHEPAPPESHNPS-----PNQQPSSFLQPSHEDS 174
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1078 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTP 1153
Cdd:PHA03169 175 PEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPTPQQAPSPNTQQAVEHEDEPTEPEREGPPFPGH 250
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
1212-1313 |
9.00e-05 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 48.73 E-value: 9.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1212 LEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAvptleEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAvsnlE 1291
Cdd:PRK12270 33 FADYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPA-----APAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAA----A 103
|
90 100
....*....|....*....|....
gi 2245149928 1292 EPASPAAAVPTPEVAAI--PAASV 1313
Cdd:PRK12270 104 AAAAPAAAAVEDEVTPLrgAAAAV 127
|
|
| PHA02030 |
PHA02030 |
hypothetical protein |
1065-1135 |
9.25e-05 |
|
hypothetical protein
Pssm-ID: 222843 [Multi-domain] Cd Length: 336 Bit Score: 47.67 E-value: 9.25e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1065 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA-AVP-TPEEPTSPaaAVPTPEEPASPAAAVpTPEEPASPAA 1135
Cdd:PHA02030 264 SNLPAVPNVAADAGSAAAPAVPAAAAAVAQAApSVPqVPNVAVLP--DVPQVAPVAAPAAPE-VPAVPVVPAA 333
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
1069-1141 |
9.43e-05 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 48.14 E-value: 9.43e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1069 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAaavPTPEEPASPAAAVPTPEEPASPAAAVPTPE 1141
Cdd:PTZ00144 120 TGGAPPAAAPAAAAAAKAEKTTPEKPKAAAPTPEPPAASK---PTPPAAAKPPEPAPAAKPPPTPVARADPRE 189
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
985-1068 |
9.51e-05 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 47.75 E-value: 9.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 985 EEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1064
Cdd:PTZ00144 104 EEGDTVEVGAPLSEIDTGGAPPAAAPAAAAAAKAEKTTPEKPKAAAPTPEPPAASKPTPPAAAKPPEPAPAAKPPPTPVA 183
|
....
gi 2245149928 1065 PTSP 1068
Cdd:PTZ00144 184 RADP 187
|
|
| CT47 |
pfam15623 |
Cancer/testis gene family 47; CT47 is a family of proteins found in eukaryotes. Proteins in ... |
1023-1116 |
9.58e-05 |
|
Cancer/testis gene family 47; CT47 is a family of proteins found in eukaryotes. Proteins in this family are typically between 262 and 291 amino acids in length. There is a conserved HIL sequence motif. The function of this family is not known.
Pssm-ID: 464779 [Multi-domain] Cd Length: 281 Bit Score: 47.24 E-value: 9.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1023 PEEPTSPAAAVPPPEEPTSPAAAVpTPEEPTSPAAAVPTPEEPTSPAAAvptpEEPTSPAAAVPTPEEPTSPAAAVPTPE 1102
Cdd:pfam15623 170 LPRLGPVGAAAPEGEGLGLPQEAA-SVEEPAVPADLAEMAREPAEEAAE----EEPAEEAAEEPAAEEPAAEAAEEPAAE 244
|
90
....*....|....
gi 2245149928 1103 EPTSPAAAVPTPEE 1116
Cdd:pfam15623 245 EAEAPEEVTKSQPE 258
|
|
| half-pint |
TIGR01645 |
poly-U binding splicing factor, half-pint family; The proteins represented by this model ... |
1032-1223 |
9.83e-05 |
|
poly-U binding splicing factor, half-pint family; The proteins represented by this model contain three RNA recognition motifs (rrm: pfam00076) and have been characterized as poly-pyrimidine tract binding proteins associated with RNA splicing factors. In the case of PUF60 (GP|6176532), in complex with p54, and in the presence of U2AF, facilitates association of U2 snRNP with pre-mRNA.
Pssm-ID: 130706 [Multi-domain] Cd Length: 612 Bit Score: 48.14 E-value: 9.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1032 AVPPPE---EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV-PTPEEPTSPAAAVPTPEEptspaaAVPTPEEPTSP 1107
Cdd:TIGR01645 281 CVTPPDallQPATVSAIPAAAAVAAAAATAKIMAAEAVAGAAVLgPRAQSPATPSSSLPTDIG------NKAVVSSAKKE 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1108 AAAVPtPEEPASPAAAVPTPEEpaspaaaVPTPEEPafpaPAVPTPEESASAAVAVPT---PEESASPAAAVPTPAESAS 1184
Cdd:TIGR01645 355 AEEVP-PLPQAAPAVVKPGPME-------IPTPVPP----PGLAIPSLVAPPGLVAPTeinPSFLASPRKKMKREKLPVT 422
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2245149928 1185 FAAVVATL--EEPTSPAASvPTPAAMVATLEEFTSPAASVP 1223
Cdd:TIGR01645 423 FGALDDTLawKEPSKEDQT-SEDGKMLAIMGEAAAALALEP 462
|
|
| PHA02030 |
PHA02030 |
hypothetical protein |
1026-1096 |
9.83e-05 |
|
hypothetical protein
Pssm-ID: 222843 [Multi-domain] Cd Length: 336 Bit Score: 47.67 E-value: 9.83e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1026 PTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAA-AVP-TPEEPTSPAaaVPTpEEPTSPAAAVPTPEEPTSPAA 1096
Cdd:PHA02030 264 SNLPAVPNVAADAGSAAAPAVPAAAAAVAQAApSVPqVPNVAVLPD--VPQ-VAPVAAPAAPEVPAVPVVPAA 333
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
1110-1208 |
1.04e-04 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 47.33 E-value: 1.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1110 AVPTPEEPASPAAAVPtpeEPASPAAAVPTP-EEPAFPAPAVPTPEESASAAVAvPTPEESASPAAAVPTPAESASFAAV 1188
Cdd:PRK10856 161 SVPLDTSTTTDPATTP---APAAPVDTTPTNsQTPAVATAPAPAVDPQQNAVVA-PSQANVDTAATPAPAAPATPDGAAP 236
|
90 100
....*....|....*....|
gi 2245149928 1189 VATLEEPTSPAASVPTPAAM 1208
Cdd:PRK10856 237 LPTDQAGVSTPAADPNALVM 256
|
|
| PHA03377 |
PHA03377 |
EBNA-3C; Provisional |
1073-1286 |
1.05e-04 |
|
EBNA-3C; Provisional
Pssm-ID: 177614 [Multi-domain] Cd Length: 1000 Bit Score: 48.51 E-value: 1.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1073 PTPEEPTSPAAAVPTPEEPTSPAaavPTPEepTSPAAAVPTPEEPASPAA--AVPTPEEPAsPAAAVPTPEEPAfpapaV 1150
Cdd:PHA03377 399 PVQQRPVMFVSRVPWRKPRTLPW---PTPK--THPVKRTLVKTSGRSDEAeqAQSTPERPG-PSDQPSVPVEPA-----H 467
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLE-------EPTSPAASVPTPA----AMVATLE------ 1213
Cdd:PHA03377 468 LTPVEHTTVILHQPPQSPPTVAIKPAPPPSRRRRGACVVYDDDiievidvETTEEEESVTQPAkphrKVQDGFQrsgrrq 547
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2245149928 1214 EFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTlEEPTSSAAAVLTPEELSSPAASVP--TPEEPASPAAA 1286
Cdd:PHA03377 548 KRATPPKVSPSDRGPPKASPPVMAPPSTGPRVMATPS-TGPRDMAPPSTGPRQQAKCKDGPPasGPHEKQPPSSA 621
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
1000-1081 |
1.08e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 48.04 E-value: 1.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1000 PASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAvPTPEEPT 1079
Cdd:PRK14948 516 SASNTAKTPPPPQKSPPPPAPTPPLPQPTATAPPPTPPPPPPTATQASSNAPAQIPADSSPPPPIPEEPTPS-PTKDSSP 594
|
..
gi 2245149928 1080 SP 1081
Cdd:PRK14948 595 EE 596
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
1251-1317 |
1.08e-04 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 48.07 E-value: 1.08e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1251 LEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVsnlEEPASPAAAVPTPEVAAIPAASVPTPE 1317
Cdd:COG5373 37 LAEAAEAASAPAEPEPEAAAAATAAAPEAAPAPVPEA---PAAPPAAAEAPAPAAAAPPAEAEPAAA 100
|
|
| PHA01929 |
PHA01929 |
putative scaffolding protein |
1001-1089 |
1.09e-04 |
|
putative scaffolding protein
Pssm-ID: 177328 Cd Length: 306 Bit Score: 47.36 E-value: 1.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1001 ASPAAAvPTPE-EPTSPAAAVPTPEEPTSPA-AAVPPPEEPTSPAAAVPTPEEPTSPAAavPTPEEPTSPAAAVPTPEEP 1078
Cdd:PHA01929 19 VPPAAA-PTPQpNPVIQPQAPVQPGQPGAPQqLAIPTQQPQPVPTSAMTPHVVQQAPAQ--PAPAAPPAAGAALPEALEV 95
|
90
....*....|.
gi 2245149928 1079 TSPAAAVPTPE 1089
Cdd:PHA01929 96 PPPPAFTPNGE 106
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
956-1074 |
1.14e-04 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 47.65 E-value: 1.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 956 AALAITVPITEEDGTPEGPVTPATTVHAPEE-PDTAAVRVSTPEEPASPAAAvPTPEEPTSPAAAVPTPEEPTSPAAAVP 1034
Cdd:PRK06995 49 AALAPPAAAAPAAAQPPPAAAPAAVSRPAAPaAEPAPWLVEHAKRLTAQREQ-LVARAAAPAAPEAQAPAAPAERAAAEN 127
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2245149928 1035 PPEEPTSPAAAVPTPeEPTSPAAAVPTPEEPTSPAAAVPT 1074
Cdd:PRK06995 128 AARRLARAAAAAPRP-RVPADAAAAVADAVKARIERIVND 166
|
|
| PRK04654 |
PRK04654 |
sec-independent translocase; Provisional |
976-1086 |
1.15e-04 |
|
sec-independent translocase; Provisional
Pssm-ID: 135173 [Multi-domain] Cd Length: 214 Bit Score: 46.34 E-value: 1.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 976 TPATTVHAPEE----PDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAvpTPEE 1051
Cdd:PRK04654 103 TSATPVATPLElahaDLSASAQVDAAAGAEPGAGQAHTPVPAPAPVIAQAQPIAPAPHQTLVPAPHDTIVPAPH--AAHL 180
|
90 100 110
....*....|....*....|....*....|....*.
gi 2245149928 1052 PTSPAAAVPT-PEEPTSPAAavPTPEEPTSPAAAVP 1086
Cdd:PRK04654 181 PSAPATPVSVaPVDAGTSAS--PTPSEPTKIQEKQP 214
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
1066-1133 |
1.16e-04 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 47.75 E-value: 1.16e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 1066 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASP 1133
Cdd:PTZ00144 120 TGGAPPAAAPAAAAAAKAEKTTPEKPKAAAPTPEPPAASKPTPPAAAKPPEPAPAAKPPPTPVARADP 187
|
|
| KLF9_13_N-like |
cd21975 |
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like ... |
953-1090 |
1.17e-04 |
|
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like transcription factors (KLFs) belong to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the related N-terminal domains of KLF9, KLF13, KLF14, KLF16, and similar proteins.
Pssm-ID: 409240 [Multi-domain] Cd Length: 163 Bit Score: 45.45 E-value: 1.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 953 PEWAALAITVPITEEDGTPEGPVTPATTVhAPEEPDTAAVRVSTPE-EPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1031
Cdd:cd21975 25 PEGAGLAAGLDVRATREVAKGPGPPGPAW-KPDGADSPGLVTAAPHlLAANVLAPLRGPSVEGSSLESGDADMGSDSDVA 103
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 1032 AVPPPEEPTSPAAAVPTPEEPtSPAAAVPTPEepTSPAAAVPTPEEPTSPAAAVPTPEE 1090
Cdd:cd21975 104 PASGAAASTSPESSSDAASSP-SPLSLLHPGE--AGLEPERPRPRVRRGVRRRGVTPAA 159
|
|
| DUF3729 |
pfam12526 |
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ... |
1093-1180 |
1.17e-04 |
|
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.
Pssm-ID: 372164 [Multi-domain] Cd Length: 115 Bit Score: 44.30 E-value: 1.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1093 SPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPeePASPAAAVPTPEEPAFPAPAvptPEESASAAVAVPTPEESASP 1172
Cdd:pfam12526 21 STSGFSSCFSPPESAHPDPPPPVGDPRPPVVDTPP--PVSAVWVLPPPSEPAAPEPD---LVPPVTGPAGPPSPLAPPAP 95
|
....*...
gi 2245149928 1173 AAAVPTPA 1180
Cdd:pfam12526 96 AQKPPLPP 103
|
|
| half-pint |
TIGR01645 |
poly-U binding splicing factor, half-pint family; The proteins represented by this model ... |
1002-1199 |
1.22e-04 |
|
poly-U binding splicing factor, half-pint family; The proteins represented by this model contain three RNA recognition motifs (rrm: pfam00076) and have been characterized as poly-pyrimidine tract binding proteins associated with RNA splicing factors. In the case of PUF60 (GP|6176532), in complex with p54, and in the presence of U2AF, facilitates association of U2 snRNP with pre-mRNA.
Pssm-ID: 130706 [Multi-domain] Cd Length: 612 Bit Score: 47.76 E-value: 1.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1002 SPAAAVPTPEEPTS--PAAAVPTpeepTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEptspaaAVPTPEEPT 1079
Cdd:TIGR01645 283 TPPDALLQPATVSAipAAAAVAA----AAATAKIMAAEAVAGAAVLGPRAQSPATPSSSLPTDIG------NKAVVSSAK 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1080 SPAAAVPtPEEPTSPAAAVPTPEEPTSPAA--AVPTPEEPASPAAAVPTPEEP---ASPAAAVPTPEEPAFPAPAVPTpe 1154
Cdd:TIGR01645 353 KEAEEVP-PLPQAAPAVVKPGPMEIPTPVPppGLAIPSLVAPPGLVAPTEINPsflASPRKKMKREKLPVTFGALDDT-- 429
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2245149928 1155 esasaaVAVPTPEESASPAAAVPTPAESASFAAvvATLEEPTSPA 1199
Cdd:TIGR01645 430 ------LAWKEPSKEDQTSEDGKMLAIMGEAAA--ALALEPKKKK 466
|
|
| PHA03269 |
PHA03269 |
envelope glycoprotein C; Provisional |
1135-1298 |
1.23e-04 |
|
envelope glycoprotein C; Provisional
Pssm-ID: 165527 [Multi-domain] Cd Length: 566 Bit Score: 47.80 E-value: 1.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1135 AAVPTPeepafpapaVPTPEESASAAVAVPTPE-ESASPAAAVPTPAESasfaavvatleePTSPAASVPTPAAMvatle 1213
Cdd:PHA03269 20 ANLNTN---------IPIPELHTSAATQKPDPApAPHQAASRAPDPAVA------------PTSAASRKPDLAQA----- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1214 efTSPAASVPTSEEPASLAAAVSNPEeptsPAAAvptleePTSSAAAVLTPEElssPAASVPTpEEPASPAAAVSNLEEP 1293
Cdd:PHA03269 74 --PTPAASEKFDPAPAPHQAASRAPD----PAVA------PQLAAAPKPDAAE---AFTSAAQ-AHEAPADAGTSAASKK 137
|
....*
gi 2245149928 1294 ASPAA 1298
Cdd:PHA03269 138 PDPAA 142
|
|
| EFh_PEF_ALG-2_like |
cd16185 |
EF-hand, calcium binding motif, found in homologs of mammalian apoptosis-linked gene 2 protein ... |
3176-3234 |
1.26e-04 |
|
EF-hand, calcium binding motif, found in homologs of mammalian apoptosis-linked gene 2 protein (ALG-2); The family includes some homologs of mammalian apoptosis-linked gene 2 protein (ALG-2) mainly found in lower eukaryotes, such as a parasitic protist Leishmarua major and a cellular slime mold Dictyostelium discoideum. These homologs contains five EF-hand motifs. Due to the presence of unfavorable residues at the Ca2+-coordinating positions, their non-canonical EF4 and EF5 hands may not bind Ca2+. Two Dictyostelium PEF proteins are the prototypes of this family. They may bind to cytoskeletal proteins and/or signal-transducing proteins localized to detergent-resistant membranes named lipid rafts, and occur as monomers or weak homo- or heterodimers like ALG-2. They can serve as a mediator for Ca2+ signaling-related Dictyostehum programmed cell death (PCD).
Pssm-ID: 320060 [Multi-domain] Cd Length: 163 Bit Score: 45.28 E-value: 1.26e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 3176 FFRRIDKDQDGKITRQEfIDGILASKFPTTKLEMTA-VADIFDRDGDGYIDYYEFvAALH 3234
Cdd:cd16185 5 WFRAVDRDRSGSIDVNE-LQKALAGGGLLFSLATAEkLIRMFDRDGNGTIDFEEF-AALH 62
|
|
| CT47 |
pfam15623 |
Cancer/testis gene family 47; CT47 is a family of proteins found in eukaryotes. Proteins in ... |
972-1064 |
1.31e-04 |
|
Cancer/testis gene family 47; CT47 is a family of proteins found in eukaryotes. Proteins in this family are typically between 262 and 291 amino acids in length. There is a conserved HIL sequence motif. The function of this family is not known.
Pssm-ID: 464779 [Multi-domain] Cd Length: 281 Bit Score: 46.85 E-value: 1.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 972 EGPVTPAttvhAPEEPDTAAVR-VSTPEEPASPAAAVPTPEEPTSPAAAvptpEEPTSPAAAVPPPEEPTSPAAAVPTPE 1050
Cdd:pfam15623 173 LGPVGAA----APEGEGLGLPQeAASVEEPAVPADLAEMAREPAEEAAE----EEPAEEAAEEPAAEEPAAEAAEEPAAE 244
|
90
....*....|....
gi 2245149928 1051 EPTSPAAAVPTPEE 1064
Cdd:pfam15623 245 EAEAPEEVTKSQPE 258
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1508-2329 |
1.34e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 48.14 E-value: 1.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1508 KAQIQEQKLLQRLLDDRKATVDMLQAEggriaqsAELADREKITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHE 1587
Cdd:TIGR02169 207 REKAERYQALLKEKREYEGYELLKEKE-------ALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNK 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1588 TAEPISDFLSVTekklansepVGTQTAKIQQQIIRHKALNEEIVNRKKNVDQAIKNGQALLKQTtgeevlliQEKLDGIK 1667
Cdd:TIGR02169 280 KIKDLGEEEQLR---------VKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL--------LAEIEELE 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1668 TRyaditVTSSKALRtleqaRQLATKFQSTYEELTGWLREVEEELATSGgqsPTGEQIPQFQQRQKELKKEVMEHRLVLD 1747
Cdd:TIGR02169 343 RE-----IEEERKRR-----DKLTEEYAELKEELEDLRAELEEVDKEFA---ETRDELKDYREKLEKLKREINELKRELD 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1748 TVNEVSRALLELVPwRAREGLDKLVSDANEqYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMA-LGP 1826
Cdd:TIGR02169 410 RLQEELQRLSEELA-DLNAAIAGIEAKINE-LEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKeLSK 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1827 IRLEQDQTTAQLQVQKAFSIDiirHKDSMDELFSHRSEIFGTC------GEEQKTVLQE-----------KTESLIQqyE 1889
Cdd:TIGR02169 488 LQRELAEAEAQARASEERVRG---GRAVEEVLKASIQGVHGTVaqlgsvGERYATAIEVaagnrlnnvvvEDDAVAK--E 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1890 AISLLNSERYAR-----LERAQV----------------LVN--QFWETYEELSPW----------IEETRALIAQL--- 1933
Cdd:TIGR02169 563 AIELLKRRKAGRatflpLNKMRDerrdlsilsedgvigfAVDlvEFDPKYEPAFKYvfgdtlvvedIEAARRLMGKYrmv 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1934 --------PSPAIDHEQLRQQQEEMRQLREsiaehkphidkllkigpqlkelnPEEGEMVEEKYQKAENMYAQIKEEVRQ 2005
Cdd:TIGR02169 643 tlegelfeKSGAMTGGSRAPRGGILFSRSE-----------------------PAELQRLRERLEGLKRELSSLQSELRR 699
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2006 RALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRmpplipAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEEL 2085
Cdd:TIGR02169 700 IENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLK------ERLEELEEDLSSLEQEIENVKSELKELEARIEELEED 773
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2086 IGRSQGADKDLAAKEIQDKLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALLTTIKDTQDIVHDLEspgIDPS 2165
Cdd:TIGR02169 774 LHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLK---EQIK 850
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2166 IIKQQVEAAETIKEETDglhEELEFIRILGADLifacgETEKPEVRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQY 2245
Cdd:TIGR02169 851 SIEKEIENLNGKKEELE---EELEELEAALRDL-----ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSEL 922
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2246 QDTLQAMFDWL---DNTVIKLCTMPPVGTDLNTVKDQLNEMKE---------FKVEvyqQQIEmEKLNHQGELMLKKATD 2313
Cdd:TIGR02169 923 KAKLEALEEELseiEDPKGEDEEIPEEELSLEDVQAELQRVEEeiralepvnMLAI---QEYE-EVLKRLDELKEKRAKL 998
|
890
....*....|....*....
gi 2245149928 2314 ETDRDIIR---EPLTELKH 2329
Cdd:TIGR02169 999 EEERKAILeriEEYEKKKR 1017
|
|
| KREPA2 |
cd23959 |
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of ... |
849-1080 |
1.36e-04 |
|
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of the parasitic protozoan's KREPA RNA editing catalytic complex (RECC). Kinetoplastid RNA editing (KRE) proteins occur as pairs or sets of related proteins in multiple complexes. KREPA complex is composed of six components (KREPA1-6), which share a conserved C-terminal region containing an oligonucleotide-binding (OB)-fold-like domain. KREPAs are responsible for the site-specific insertion and deletion of U nucleotides in the kinetoplastid mitochondria pre-messenger RNA. Apart from the conserved C-terminal OB-fold domain, KREPA1, KREPA2, and KREPA3 contain two conserved C2H2 zinc-finger domains. KREPA2 and kinetoplastid RNA editing ligase 1 (KREL1) are specific for ligation post-U-deletion and are paralogous to KREL2 and KREPA1 that are specific for ligation post-U-insertion. KREPA2, is critical for RECC stability and KREL1 integration into the complex.
Pssm-ID: 467780 [Multi-domain] Cd Length: 424 Bit Score: 47.56 E-value: 1.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 849 AALPS-PEEGTSIAAVPAPEGtavvaalvPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVpeGTAAVAAVS 927
Cdd:cd23959 47 AARPSdQEEPLYGAVSPEGEN--------PFDGPGLVTASTVSDCYVGNANFYEVDMSDAFAMAPDESL--GPFRAARVP 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 928 SPeetapavaaaitqegMSAVAGFSPEWAALAITVPITEEDGTPegPVTPATTV-----HAPEEPDTAAVRVSTPEepAS 1002
Cdd:cd23959 117 NP---------------FSASSSTQRETHKTAQVAPPKAEPQTA--PVTPFGQLpmfgqHPPPAKPLPAAAAAQQS--SA 177
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 1003 PAAAVPtpeeptSPAAAVPTPEEPTSPAAAVPPPeePTSPAAAVPTPEEPtSPAAAVPTPEepTSPAAAVPTPEEPTS 1080
Cdd:cd23959 178 SPGEVA------SPFASGTVSASPFATATDTAPS--SGAPDGFPAEASAP-SPFAAPASAA--SFPAAPVANGEAATP 244
|
|
| PRK10905 |
PRK10905 |
cell division protein DamX; Validated |
1122-1313 |
1.39e-04 |
|
cell division protein DamX; Validated
Pssm-ID: 236792 [Multi-domain] Cd Length: 328 Bit Score: 47.24 E-value: 1.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1122 AAVPTPEEPASPAAAVPTPEEPAFPA-PAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPA- 1199
Cdd:PRK10905 50 GVQPAPGTTSAEQTAGNTQQDVSLPPiSSTPTQGQTPVATDGQQRVEVQGDLNNALTQPQNQQQLNNVAVNSTLPTEPAt 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1200 -ASVPTPAAMVATLEEFTSPAASVPTSE------EPASLAAAVSNPEEPTspaAAVPTLEEPTSSAAAVLTPEELSSPAa 1272
Cdd:PRK10905 130 vAPVRNGNASRQTAKTQTAERPATTRPArkqaviEPKKPQATAKTEPKPV---AQTPKRTEPAAPVASTKAPAATSTPA- 205
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2245149928 1273 svPTPEEPASPAAAvsnleepASPAAAVPTPEVAAIPAASV 1313
Cdd:PRK10905 206 --PKETATTAPVQT-------ASPAQTTATPAAGGKTAGNV 237
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
1092-1157 |
1.43e-04 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 47.37 E-value: 1.43e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1092 TSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESA 1157
Cdd:PTZ00144 120 TGGAPPAAAPAAAAAAKAEKTTPEKPKAAAPTPEPPAASKPTPPAAAKPPEPAPAAKPPPTPVARA 185
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
1095-1160 |
1.44e-04 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 47.37 E-value: 1.44e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1095 AAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAA 1160
Cdd:PTZ00144 120 TGGAPPAAAPAAAAAAKAEKTTPEKPKAAAPTPEPPAASKPTPPAAAKPPEPAPAAKPPPTPVARA 185
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
1209-1292 |
1.46e-04 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 47.69 E-value: 1.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1209 VATLE-EFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEelsspAASVPTPEEPASPAAAV 1287
Cdd:COG5373 30 VEELEaELAEAAEAASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPA-----AAAPPAEAEPAAAPAAA 104
|
....*
gi 2245149928 1288 SNLEE 1292
Cdd:COG5373 105 SSFEE 109
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
1056-1128 |
1.50e-04 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 47.37 E-value: 1.50e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1056 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAaavPTPEEPTSPAAAVPTPEEPASPAAAVPTPE 1128
Cdd:PTZ00144 120 TGGAPPAAAPAAAAAAKAEKTTPEKPKAAAPTPEPPAASK---PTPPAAAKPPEPAPAAKPPPTPVARADPRE 189
|
|
| PHA03308 |
PHA03308 |
transcriptional regulator ICP4; Provisional |
984-1152 |
1.51e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 165563 [Multi-domain] Cd Length: 1463 Bit Score: 47.88 E-value: 1.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 984 PEEPDTAA--VRVSTPE--EPASPAAAVPTPEEPTsPAAAVPTPEEPTSPAAAVPPPEEPtsPAAAVPTPE---EPTSPA 1056
Cdd:PHA03308 728 PGTPDRAAhlLLYGSPGggDGAEPSAAQESPANPW-PRAPPCDEQEPLSVSPYGPEPDRP--PDDDFETRKglkRKSSED 804
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1057 AAVPTPE----EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAaavpTPEEPTSPAAavptpEEPASPAAavptPEEPAS 1132
Cdd:PHA03308 805 HADPIPEgnatKKTCGLQGLPDSLPPAVPETDRDNPLLPPCPI----TPEGPPCPPR-----EEPQQPQE----PQEPQS 871
|
170 180
....*....|....*....|.
gi 2245149928 1133 PAAAVPTPEEPAF-PAPAVPT 1152
Cdd:PHA03308 872 PSFHISEIGEALFhSTPVSPT 892
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
1130-1232 |
1.58e-04 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 47.96 E-value: 1.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1130 PASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAvPTPAESASFAAVVATLEEPTSPAAsvPTPAAMV 1209
Cdd:PRK12270 38 PGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAP-PKPAAAAAAAAAPAAPPAAAAAAA--PAAAAVE 114
|
90 100
....*....|....*....|...
gi 2245149928 1210 ATLEEFTSPAASVPTSEEpASLA 1232
Cdd:PRK12270 115 DEVTPLRGAAAAVAKNMD-ASLE 136
|
|
| rad23 |
TIGR00601 |
UV excision repair protein Rad23; All proteins in this family for which functions are known ... |
1066-1240 |
1.66e-04 |
|
UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273167 [Multi-domain] Cd Length: 378 Bit Score: 47.20 E-value: 1.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1066 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV----PTPEEPTSPAaavptpeePASPAAAVPTPEEPASPAAAVPTPE 1141
Cdd:TIGR00601 85 APPAATPTSAPTPTPSPPASPASGMSAAPASAVeeksPSEESATATA--------PESPSTSVPSSGSDAASTLVVGSER 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1142 EPAF-----------------------PAPAVP-----TPEESASAAVAVPTpeeSASPAAA-VPTPAESASF-AAVVAT 1191
Cdd:TIGR00601 157 ETTIeeimemgyereeveralraafnnPDRAVEylltgIPEDPEQPEPVQQT---AASTAAAtTETPQHGSVFeQAAQGG 233
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1192 LEEPTSPAASVPTPAAMVATLEEFTS--------PAASVPTSEE-----PASLAAAVSNPEE 1240
Cdd:TIGR00601 234 TEQPATEAAQGGNPLEFLRNQPQFQQlrqvvqqnPQLLPPLLQQigqenPQLLQQISQHPEQ 295
|
|
| PHA01929 |
PHA01929 |
putative scaffolding protein |
975-1063 |
1.68e-04 |
|
putative scaffolding protein
Pssm-ID: 177328 Cd Length: 306 Bit Score: 46.59 E-value: 1.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 975 VTPATTVHAPEEPDTAAVRVSTPEEPASPA-AAVPTPEE---PTSPAAAVPTPEEPTSPAAAVPPPeeptsPAAAVPTPE 1050
Cdd:PHA01929 19 VPPAAAPTPQPNPVIQPQAPVQPGQPGAPQqLAIPTQQPqpvPTSAMTPHVVQQAPAQPAPAAPPA-----AGAALPEAL 93
|
90
....*....|...
gi 2245149928 1051 EPTSPAAAVPTPE 1063
Cdd:PHA01929 94 EVPPPPAFTPNGE 106
|
|
| PRK04654 |
PRK04654 |
sec-independent translocase; Provisional |
1041-1144 |
1.70e-04 |
|
sec-independent translocase; Provisional
Pssm-ID: 135173 [Multi-domain] Cd Length: 214 Bit Score: 45.96 E-value: 1.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1041 SPAAAVPTPEE----PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA-AVPTPE 1115
Cdd:PRK04654 103 TSATPVATPLElahaDLSASAQVDAAAGAEPGAGQAHTPVPAPAPVIAQAQPIAPAPHQTLVPAPHDTIVPAPhAAHLPS 182
|
90 100
....*....|....*....|....*....
gi 2245149928 1116 EPASPAAAVPTPeepaSPAAAVPTPEEPA 1144
Cdd:PRK04654 183 APATPVSVAPVD----AGTSASPTPSEPT 207
|
|
| PHA02030 |
PHA02030 |
hypothetical protein |
1039-1109 |
1.77e-04 |
|
hypothetical protein
Pssm-ID: 222843 [Multi-domain] Cd Length: 336 Bit Score: 46.90 E-value: 1.77e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1039 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA-AVP-TPEEPTSPAaaVPTpEEPTSPAAAVPTPEEPTSPAA 1109
Cdd:PHA02030 264 SNLPAVPNVAADAGSAAAPAVPAAAAAVAQAApSVPqVPNVAVLPD--VPQ-VAPVAAPAAPEVPAVPVVPAA 333
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
1062-1185 |
1.77e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 47.46 E-value: 1.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1062 PEEPTSPAAAVPTPEEPTsPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPtPEEPASPAAAVPTPEEPASPAAAVPTPE 1141
Cdd:PRK14971 375 PKQHIKPVFTQPAAAPQP-SAAAAASPSPSQSSAAAQPSAPQSATQPAGTP-PTVSVDPPAAVPVNPPSTAPQAVRPAQF 452
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 2245149928 1142 EPAFPAPAVPTPEESASAAVAVPTPEESAS-PAAAVPTPAESASF 1185
Cdd:PRK14971 453 KEEKKIPVSKVSSLGPSTLRPIQEKAEQATgNIKEAPTGTQKEIF 497
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
1014-1138 |
1.82e-04 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 47.02 E-value: 1.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1014 TSPAAAvPTPEEPTSPAAAVPPPEEPTSPAAAVPTPeeptspaaaVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1093
Cdd:PRK12799 298 TVPVAA-VTPSSAVTQSSAITPSSAAIPSPAVIPSS---------VTTQSATTTQASAVALSSAGVLPSDVTLPGTVALP 367
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 2245149928 1094 PAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP 1138
Cdd:PRK12799 368 AAEPVNMQPQPMSTTETQQSSTGNITSTANGPTTSLPAAPASNIP 412
|
|
| PRK04654 |
PRK04654 |
sec-independent translocase; Provisional |
1080-1183 |
1.82e-04 |
|
sec-independent translocase; Provisional
Pssm-ID: 135173 [Multi-domain] Cd Length: 214 Bit Score: 45.57 E-value: 1.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1080 SPAAAVPTPEE----PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPaVPTPEE 1155
Cdd:PRK04654 103 TSATPVATPLElahaDLSASAQVDAAAGAEPGAGQAHTPVPAPAPVIAQAQPIAPAPHQTLVPAPHDTIVPAP-HAAHLP 181
|
90 100
....*....|....*....|....*...
gi 2245149928 1156 SASAAVAVPTPEESASPAAavPTPAESA 1183
Cdd:PRK04654 182 SAPATPVSVAPVDAGTSAS--PTPSEPT 207
|
|
| DedD |
COG3147 |
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, ... |
1078-1145 |
1.89e-04 |
|
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442381 [Multi-domain] Cd Length: 140 Bit Score: 44.38 E-value: 1.89e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 1078 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEepASPAAAVPTPEEPASPAAAVPTPEEPAF 1145
Cdd:COG3147 1 PAEEAAAAPAAAAAPAAPAAAAAPAPAAAAAAAAPKPA--AKPAAPKPAAAAAAAPAAKAAAPAGGGW 66
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
905-1051 |
1.89e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 47.11 E-value: 1.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 905 ERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAaaitqegmsavagfspewaalaitvPITEEDGTPEGPVTPATTVHAP 984
Cdd:PRK14950 352 ELAVIEALLVPVPAPQPAKPTAAAPSPVRPTPA-------------------------PSTRPKAAAAANIPPKEPVRET 406
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 985 EEPDTAAVRVSTPEEPASPAAAvptpeePTSPAAAVPTPEEPTSPAAAvPPPEEPTSPAAAVPTPEE 1051
Cdd:PRK14950 407 ATPPPVPPRPVAPPVPHTPESA------PKLTRAAIPVDEKPKYTPPA-PPKEEEKALIADGDVLEQ 466
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1487-2043 |
1.91e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.45 E-value: 1.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1487 LADTEELIANQKPPSAEYKVVKAQIQE-QKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQLESLESRWTELL 1565
Cdd:COG4717 73 LKELEEELKEAEEKEEEYAELQEELEElEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELE 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1566 SKAAARQKQLEDILVLAKQFHETAEPIsdflsvteKKLANSEPVGTQTAkIQQQIIRHKALNEEIVNRKKNVDQAIkngq 1645
Cdd:COG4717 153 ERLEELRELEEELEELEAELAELQEEL--------EELLEQLSLATEEE-LQDLAEELEELQQRLAELEEELEEAQ---- 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1646 allkqttgEEVLLIQEKLDGIKTRyaditVTSSKALRTLEQARQLA------TKFQSTYEELTGWLREVEEELATSGGQS 1719
Cdd:COG4717 220 --------EELEELEEELEQLENE-----LEAAALEERLKEARLLLliaaalLALLGLGGSLLSLILTIAGVLFLVLGLL 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1720 PTGeqiPQFQQRQKELKKEVMEHRLVLDTVNEVSRAllELVPWRAREGLDKLVSdaneqyklvsdtigqrVDEIDAAIQR 1799
Cdd:COG4717 287 ALL---FLLLAREKASLGKEAEELQALPALEELEEE--ELEELLAALGLPPDLS----------------PEELLELLDR 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1800 SQQYEQAADAelawvAETKRKLMALGPIRLEQDQTTAQLQVqkafsidiirhkdSMDELFSHRSEIFgtcgeEQKTVLQE 1879
Cdd:COG4717 346 IEELQELLRE-----AEELEEELQLEELEQEIAALLAEAGV-------------EDEEELRAALEQA-----EEYQELKE 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1880 KTESLIQQYEAISLLNSERYARLERAQVLvnqfwETYEELspwieetraliaqlpspaidHEQLRQQQEEMRQLRESIAE 1959
Cdd:COG4717 403 ELEELEEQLEELLGELEELLEALDEEELE-----EELEEL--------------------EEELEELEEELEELREELAE 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1960 HKPHIDKLlkigpqlkelnpEEGEMVEEKYQKAENMYAQIKEEVRQRALA--LDEAVSQStqITEFHDKIEPmlETLENL 2037
Cdd:COG4717 458 LEAELEQL------------EEDGELAELLQELEELKAELRELAEEWAALklALELLEEA--REEYREERLP--PVLERA 521
|
....*.
gi 2245149928 2038 SSRLRM 2043
Cdd:COG4717 522 SEYFSR 527
|
|
| KLF9_13_N-like |
cd21975 |
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like ... |
1125-1271 |
1.96e-04 |
|
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like transcription factors (KLFs) belong to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the related N-terminal domains of KLF9, KLF13, KLF14, KLF16, and similar proteins.
Pssm-ID: 409240 [Multi-domain] Cd Length: 163 Bit Score: 44.68 E-value: 1.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1125 PTPEEPASPAAAVPTPEEPAFPAPAVPTPEEsasaavaVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPT 1204
Cdd:cd21975 23 PDPEGAGLAAGLDVRATREVAKGPGPPGPAW-------KPDGADSPGLVTAAPHLLAANVLAPLRGPSVEGSSLESGDAD 95
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1205 paaMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPA 1271
Cdd:cd21975 96 ---MGSDSDVAPASGAAASTSPESSSDAASSPSPLSLLHPGEAGLEPERPRPRVRRGVRRRGVTPAA 159
|
|
| PHA02030 |
PHA02030 |
hypothetical protein |
1052-1122 |
1.96e-04 |
|
hypothetical protein
Pssm-ID: 222843 [Multi-domain] Cd Length: 336 Bit Score: 46.51 E-value: 1.96e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1052 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA-AVP-TPEEPTSPAaaVPTpEEPTSPAAAVPTPEEPASPAA 1122
Cdd:PHA02030 264 SNLPAVPNVAADAGSAAAPAVPAAAAAVAQAApSVPqVPNVAVLPD--VPQ-VAPVAAPAAPEVPAVPVVPAA 333
|
|
| PHA03169 |
PHA03169 |
hypothetical protein; Provisional |
982-1205 |
2.04e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 46.89 E-value: 2.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 982 HAPEEPDTAAvRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPT 1061
Cdd:PHA03169 26 HGGTREQAGR-RRGTAARAAKPAPPAPTTSGPQVRAVAEQGHRQTESDTETAEESRHGEKEERGQGGPSGSGSESVGSPT 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1062 PEEPTSP--AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPT 1139
Cdd:PHA03169 105 PSPSGSAeeLASGLSPENTSGSSPESPASHSPPPSPPSHPGPHEPAPPESHNPSPNQQPSSFLQPSHEDSPEEPEPPTSE 184
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1140 PEEPAFPAPAVPTPEESASAAvavPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTP 1205
Cdd:PHA03169 185 PEPDSPGPPQSETPTSSPPPQ---SPPDEPGEPQSPTPQQAPSPNTQQAVEHEDEPTEPEREGPPF 247
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
1123-1221 |
2.06e-04 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 46.56 E-value: 2.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1123 AVPTPEEPASPAAAVPTPeepafPAPAVPTPEESASAAVAVPTPEESASPAAAV--PTPAESASFAAVVATLEEPTSPAA 1200
Cdd:PRK10856 161 SVPLDTSTTTDPATTPAP-----AAPVDTTPTNSQTPAVATAPAPAVDPQQNAVvaPSQANVDTAATPAPAAPATPDGAA 235
|
90 100
....*....|....*....|.
gi 2245149928 1201 SVPTPAAMVATleeftsPAAS 1221
Cdd:PRK10856 236 PLPTDQAGVST------PAAD 250
|
|
| PLN02983 |
PLN02983 |
biotin carboxyl carrier protein of acetyl-CoA carboxylase |
1007-1130 |
2.07e-04 |
|
biotin carboxyl carrier protein of acetyl-CoA carboxylase
Pssm-ID: 215533 [Multi-domain] Cd Length: 274 Bit Score: 45.99 E-value: 2.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1007 VPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAaaVPTPEE----------------------------------- 1051
Cdd:PLN02983 59 VAVDGSSNSAKSDDPKSEVAPSEPKDEPPSNSSSKPN--LPDEESisefmtqvsslvklvdsrdivelqlkqldcelvir 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1052 -----PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPeeptSPAAAVPTPEEPTSPAAAVPTPEepaSPAAAV-- 1124
Cdd:PLN02983 137 kkealPQPPPPAPVVMMQPPPPHAMPPASPPAAQPAPSAPAS----SPPPTPASPPPAKAPKSSHPPLK---SPMAGTfy 209
|
....*...
gi 2245149928 1125 --PTPEEP 1130
Cdd:PLN02983 210 rsPAPGEP 217
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
1079-1146 |
2.14e-04 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 46.98 E-value: 2.14e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 1079 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFP 1146
Cdd:PTZ00144 120 TGGAPPAAAPAAAAAAKAEKTTPEKPKAAAPTPEPPAASKPTPPAAAKPPEPAPAAKPPPTPVARADP 187
|
|
| ftsN |
TIGR02223 |
cell division protein FtsN; FtsN is a poorly conserved protein active in cell division in a ... |
1003-1176 |
2.15e-04 |
|
cell division protein FtsN; FtsN is a poorly conserved protein active in cell division in a number of Proteobacteria. The N-terminal 30 residue region tends to by Lys/Arg-rich, and is followed by a membrane-spanning region. This is followed by an acidic low-complexity region of variable length and a well-conserved C-terminal domain of two tandem regions matched by pfam05036 (Sporulation related repeat), found in several cell division and sporulation proteins. The role of FtsN as a suppressor for other cell division mutations is poorly understood; it may involve cell wall hydrolysis. [Cellular processes, Cell division]
Pssm-ID: 274041 [Multi-domain] Cd Length: 298 Bit Score: 46.22 E-value: 2.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1003 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPtSPAAAVPTPEEPTSPAAAVPTPEEP---T 1079
Cdd:TIGR02223 53 QANEPETLQPKNQTENGETAADLPPKPEERWSYIEELEAREVLINDPEEP-SNGGGVEESAQLTAEQRQLLEQMQAdmrA 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1080 SPAAAVPTPEE----PTSPAAAVPTPEEPTSPAAAVPTPEEpASPAAAVPTPEEPASPAAAVPTPEEPAFPAPaVPTPEE 1155
Cdd:TIGR02223 132 AEKVLATAPSEqtvaVEARKQTAEKKPQKARTAEAQKTPVE-TEKIASKVKEAKQKQKALPKQTAETQSNSKP-IETAPK 209
|
170 180
....*....|....*....|.
gi 2245149928 1156 SASAAVAVPTPEESASPAAAV 1176
Cdd:TIGR02223 210 ADKADKTKPKPKEKAERAAAL 230
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
1136-1238 |
2.21e-04 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 46.56 E-value: 2.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1136 AVPTPEEPAFPAPAVPTPeesasAAVAVPTPEESASPAAAV-PTPAESASFAAVVATLEEPTSPAA-SVPTPAAMVATle 1213
Cdd:PRK10856 161 SVPLDTSTTTDPATTPAP-----AAPVDTTPTNSQTPAVATaPAPAVDPQQNAVVAPSQANVDTAAtPAPAAPATPDG-- 233
|
90 100
....*....|....*....|....*
gi 2245149928 1214 eftspAASVPTSEEPASLAAAVSNP 1238
Cdd:PRK10856 234 -----AAPLPTDQAGVSTPAADPNA 253
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
962-1047 |
2.29e-04 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 46.56 E-value: 2.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 962 VPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASP----AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPE 1037
Cdd:PRK10856 162 VPLDTSTTTDPATTPAPAAPVDTTPTNSQTPAVATAPAPAVDpqqnAVVAPSQANVDTAATPAPAAPATPDGAAPLPTDQ 241
|
90
....*....|
gi 2245149928 1038 EPTSPAAAVP 1047
Cdd:PRK10856 242 AGVSTPAADP 251
|
|
| PHA02777 |
PHA02777 |
major capsid L1 protein; Provisional |
1026-1316 |
2.30e-04 |
|
major capsid L1 protein; Provisional
Pssm-ID: 165142 Cd Length: 555 Bit Score: 46.95 E-value: 2.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1026 PTSPAAAVPP----PEEPTSPAAAVPTPEEPTSPAaaVPTPEEPTSPAAAvptpEEPTSPAAaVPtPEEPTspaaavpTP 1101
Cdd:PHA02777 79 PSIPAGAIGPgdiiPIDAEAGALAEEIELLPMAPI--SGRARDPFGEGFG----EEPFDPIG-IP-PERPN-------IL 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1102 EEPTSPAAAVPTPEEPaSPAAAVPTPEEPASPAAAVPTPEepafpAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAE 1181
Cdd:PHA02777 144 HEQRFPTDAAPFDNGN-TDIATIEGPHDPFGAGGDIAIIE-----LPSVNDPGPSVTARTQYNNPAFEVEIHSDIPSAET 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1182 SASFAAVVATleeptspaasvPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNP-EEPTSPAAAVPTLEEPTSSAAA 1260
Cdd:PHA02777 218 SSTDHIIVGA-----------ESGGSFVGDDAEFEIPLLDAERAILDDQADTSFIAHgEEEEAFLTSTPDPVLPIQEAIA 286
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1261 VLTPEELSSPAASVPTPEEPASPAAAVSnLEEPASPAAAVPTPEVAAIPAASVPTP 1316
Cdd:PHA02777 287 PIRPYGRQFGQVRVGDAAFLDRAAVLFQ-AENPAFDADISILFEDDLADAERLDDD 341
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
1082-1214 |
2.31e-04 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 46.88 E-value: 2.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1082 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAV 1161
Cdd:PRK06995 49 AALAPPAAAAPAAAQPPPAAAPAAVSRPAAPAAEPAPWLVEHAKRLTAQREQLVARAAAPAAPEAQAPAAPAERAAAENA 128
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1162 AVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEE 1214
Cdd:PRK06995 129 ARRLARAAAAAPRPRVPADAAAAVADAVKARIERIVNDTVMQELRSLRGMLEE 181
|
|
| PRK04654 |
PRK04654 |
sec-independent translocase; Provisional |
1054-1152 |
2.38e-04 |
|
sec-independent translocase; Provisional
Pssm-ID: 135173 [Multi-domain] Cd Length: 214 Bit Score: 45.19 E-value: 2.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1054 SPAAAVPTPEE----PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAA-AVPTPE 1128
Cdd:PRK04654 103 TSATPVATPLElahaDLSASAQVDAAAGAEPGAGQAHTPVPAPAPVIAQAQPIAPAPHQTLVPAPHDTIVPAPhAAHLPS 182
|
90 100
....*....|....*....|....*
gi 2245149928 1129 EPASPAAAVPTPE-EPAFPAPAVPT 1152
Cdd:PRK04654 183 APATPVSVAPVDAgTSASPTPSEPT 207
|
|
| PHA02030 |
PHA02030 |
hypothetical protein |
1013-1083 |
2.44e-04 |
|
hypothetical protein
Pssm-ID: 222843 [Multi-domain] Cd Length: 336 Bit Score: 46.51 E-value: 2.44e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1013 PTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAA-AVP-TPEEPTSPAaaVPTpEEPTSPAAAVPTPEEPTSPAA 1083
Cdd:PHA02030 264 SNLPAVPNVAADAGSAAAPAVPAAAAAVAQAApSVPqVPNVAVLPD--VPQ-VAPVAAPAAPEVPAVPVVPAA 333
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
1040-1107 |
2.45e-04 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 46.60 E-value: 2.45e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 1040 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1107
Cdd:PTZ00144 120 TGGAPPAAAPAAAAAAKAEKTTPEKPKAAAPTPEPPAASKPTPPAAAKPPEPAPAAKPPPTPVARADP 187
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1531-2152 |
2.47e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.44 E-value: 2.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1531 LQAEGGRIAQSAELADREKITGQL-ESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDflSVTEKKLANSepv 1609
Cdd:PTZ00121 1272 IKAEEARKADELKKAEEKKKADEAkKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKK--KAEEAKKAAE--- 1346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1610 gTQTAKIQQQIIRHKALNEEIVNRKKNVDQAIKNGQALLKQttGEEVlliqEKLDGIKTRyADITVTSSKALRTLEQARQ 1689
Cdd:PTZ00121 1347 -AAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK--AEEK----KKADEAKKK-AEEDKKKADELKKAAAAKK 1418
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1690 LATKFQSTYEELtgwlREVEEelatsggqsptGEQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRAllelvpwRAREGLD 1769
Cdd:PTZ00121 1419 KADEAKKKAEEK----KKADE-----------AKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEA-------KKADEAK 1476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1770 KLVSDAN--EQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKlmalGPIRLEQDQTTAQLQVQKAfsiD 1847
Cdd:PTZ00121 1477 KKAEEAKkaDEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKK----AEEAKKADEAKKAEEKKKA---D 1549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1848 IIRHKDSMDElfshrseifgtcGEEQKTVLQEKTEsliQQYEAISLLNSERYARLERAQVlvnqfwetyEELSPWIEETR 1927
Cdd:PTZ00121 1550 ELKKAEELKK------------AEEKKKAEEAKKA---EEDKNMALRKAEEAKKAEEARI---------EEVMKLYEEEK 1605
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1928 ALIAQLPSPA----IDHEQLRQQQEEMR---QLRESIAEHKPHIDKLLKIGPQLKELNPEEGEMVEEKYQKAENMYAQiK 2000
Cdd:PTZ00121 1606 KMKAEEAKKAeeakIKAEELKKAEEEKKkveQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKA-E 1684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2001 EEVRQRALALDEAVSQSTQITEFHDKIEpmletlenlssrlrmpplipAEVDKIRECISDNKSATVELEKLQPSFEALKR 2080
Cdd:PTZ00121 1685 EDEKKAAEALKKEAEEAKKAEELKKKEA--------------------EEKKKAEELKKAEEENKIKAEEAKKEAEEDKK 1744
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 2081 RGEEligrsqgadkdLAAKEIQDKLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALLTTIKDTQD 2152
Cdd:PTZ00121 1745 KAEE-----------AKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFD 1805
|
|
| CT47 |
pfam15623 |
Cancer/testis gene family 47; CT47 is a family of proteins found in eukaryotes. Proteins in ... |
1062-1155 |
2.53e-04 |
|
Cancer/testis gene family 47; CT47 is a family of proteins found in eukaryotes. Proteins in this family are typically between 262 and 291 amino acids in length. There is a conserved HIL sequence motif. The function of this family is not known.
Pssm-ID: 464779 [Multi-domain] Cd Length: 281 Bit Score: 46.08 E-value: 2.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1062 PEEPTSPAAAVPTPEEPTSPAAAVpTPEEPTSPAAAVPTPEEPTSPAAAvptpEEPASPAAAVPTPEEPASPAAAVPTPE 1141
Cdd:pfam15623 170 LPRLGPVGAAAPEGEGLGLPQEAA-SVEEPAVPADLAEMAREPAEEAAE----EEPAEEAAEEPAAEEPAAEAAEEPAAE 244
|
90
....*....|....
gi 2245149928 1142 EPAFPAPAVPTPEE 1155
Cdd:pfam15623 245 EAEAPEEVTKSQPE 258
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
1219-1363 |
2.57e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 46.79 E-value: 2.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1219 AASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAA 1298
Cdd:PRK12323 372 AGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPA 451
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2245149928 1299 AVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEvsPIGVPflgvSAHTDSVPISEEGTPVLEEAS 1363
Cdd:PRK12323 452 PAPAAAPAAAARPAAAGPRPVAAAAAAAPARAA--PAAAP----APADDDPPPWEELPPEFASPA 510
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1154-1316 |
2.58e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 47.09 E-value: 2.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1154 EESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPaamvaTLEEFTSPAASVPTSEEPASLAA 1233
Cdd:PHA03307 12 EAAAEGGEFFPRPPATPGDAADDLLSGSQGQLVSDSAELAAVTVVAGAAACD-----RFEPPTGPPPGPGTEAPANESRS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1234 AVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASV 1313
Cdd:PHA03307 87 TPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDA 166
|
...
gi 2245149928 1314 PTP 1316
Cdd:PHA03307 167 ASS 169
|
|
| FAP |
pfam07174 |
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment ... |
1131-1277 |
2.60e-04 |
|
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment proteins (FAP). Family members are rich in alanine and proline, are approximately 300 long, and seem to be restricted to mycobacteria. These proteins contain a fibronectin-binding motif that allows mycobacteria to bind to fibronectin in the extracellular matrix.
Pssm-ID: 429334 Cd Length: 301 Bit Score: 46.07 E-value: 2.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1131 ASPAAAVPTPEepafPAPAVPTPEESASAavavpTPEESASPAAAVPTPAESASFAAVVATleEPTSPAASVPTPAamva 1210
Cdd:pfam07174 32 ALPAVAHADPE----PAPPPPSTATAPPA-----PPPPPPAPAAPAPPPPPAAPNAPNAPP--PPADPNAPPPPPA---- 96
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2245149928 1211 tleeftSPAASVPTSEEP-ASLAAAVSNPEEPTS---PAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTP 1277
Cdd:pfam07174 97 ------DPNAPPPPAVDPnAPEPGRIDNAVGGFSyvvPAGWVESDATHLDYGSALLSKTTGQPPEGGQPPP 161
|
|
| PRK11901 |
PRK11901 |
hypothetical protein; Reviewed |
1027-1159 |
2.61e-04 |
|
hypothetical protein; Reviewed
Pssm-ID: 237015 [Multi-domain] Cd Length: 327 Bit Score: 46.21 E-value: 2.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1027 TSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP-------EEP----------------TSPAA 1083
Cdd:PRK11901 88 SSGNQSSPSAANNTSDGHDASGVKNTAPPQDISAPPISPTPTQAAPPQTpngqqriELPgnisdalsqqqgqvnaASQNA 167
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1084 AVPTPEEPTSPAAaVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVpTPEEPAFPAPAVPTPEESASA 1159
Cdd:PRK11901 168 QGNTSTLPTAPAT-VAPSKGAKVPATAETHPTPPQKPATKKPAVNHHKTATVAV-PPATSGKPKSGAASARALSSA 241
|
|
| PLN02983 |
PLN02983 |
biotin carboxyl carrier protein of acetyl-CoA carboxylase |
1000-1078 |
2.71e-04 |
|
biotin carboxyl carrier protein of acetyl-CoA carboxylase
Pssm-ID: 215533 [Multi-domain] Cd Length: 274 Bit Score: 45.99 E-value: 2.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1000 PASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPeeptSPAAAVPTPEEPTSPAAAVPTPEeptSPAAAV----PTP 1075
Cdd:PLN02983 142 PQPPPPAPVVMMQPPPPHAMPPASPPAAQPAPSAPAS----SPPPTPASPPPAKAPKSSHPPLK---SPMAGTfyrsPAP 214
|
...
gi 2245149928 1076 EEP 1078
Cdd:PLN02983 215 GEP 217
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
1053-1120 |
2.72e-04 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 46.60 E-value: 2.72e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 1053 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASP 1120
Cdd:PTZ00144 120 TGGAPPAAAPAAAAAAKAEKTTPEKPKAAAPTPEPPAASKPTPPAAAKPPEPAPAAKPPPTPVARADP 187
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
975-1316 |
2.97e-04 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 46.98 E-value: 2.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 975 VTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTS-PAAAVPPPEEPTSPAAAVPTPEEPT 1053
Cdd:PHA03378 417 VTDPSVIKAIEEEHRKKKAARTEQPRATPHSQAPTVVLHRPPTQPLEGPTGPLSvQAPLEPWQPLPHPQVTPVILHQPPA 496
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1054 SPAAAVPT-----------PEEPTSPAAAVPTPEEPTSPAAA--VPTPE---EPTSPAAAVPTPEEPTSPAAAVPTPEEP 1117
Cdd:PHA03378 497 QGVQAHGSmldllekddedMEQRVMATLLPPSPPQPRAGRRApcVYTEDldiESDEPASTEPVHDQLLPAPGLGPLQIQP 576
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1118 -ASPAAAVPTPEEPASPAAAVPTPEEPAFPAPavPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAavVATLEEPT 1196
Cdd:PHA03378 577 lTSPTTSQLASSAPSYAQTPWPVPHPSQTPEP--PTTQSHIPETSAPRQWPMPLRPIPMRPLRMQPITFN--VLVFPTPH 652
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1197 SPAASVPTPAAmvatleeftspaasvPTSEEPASLAAavsNPEePTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASvPT 1276
Cdd:PHA03378 653 QPPQVEITPYK---------------PTWTQIGHIPY---QPS-PTGANTMLPIQWAPGTMQPPPRAPTPMRPPAAP-PG 712
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 2245149928 1277 PEEPasPAAAVSnleePASPAAAVPTpevAAIPAASVPTP 1316
Cdd:PHA03378 713 RAQR--PAAATG----RARPPAAAPG---RARPPAAAPGR 743
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
1118-1243 |
3.04e-04 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 46.25 E-value: 3.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1118 ASPAAAVPtpEEPASPAAAVPTPEEPAFPAPA-VPTPEESASAAVavptpeeSASPAAAVPTPAESASFAAVVATLEEP- 1195
Cdd:PRK12799 298 TVPVAAVT--PSSAVTQSSAITPSSAAIPSPAvIPSSVTTQSATT-------TQASAVALSSAGVLPSDVTLPGTVALPa 368
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 2245149928 1196 TSPAASVPTPAAMVATLEEFT---SPAASVPTSEEPAslAAAVSNPEEPTS 1243
Cdd:PRK12799 369 AEPVNMQPQPMSTTETQQSSTgniTSTANGPTTSLPA--APASNIPVSPTS 417
|
|
| PDHac_trf_long |
TIGR01348 |
pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; This model ... |
1155-1303 |
3.09e-04 |
|
pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; This model describes a subset of pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase specifically close by both phylogenetic and per cent identity (UPGMA) trees. Members of this set include two or three copies of the lipoyl-binding domain. E. coli AceF is a member of this model, while mitochondrial and some other bacterial forms belong to a separate model. [Energy metabolism, Pyruvate dehydrogenase]
Pssm-ID: 273566 [Multi-domain] Cd Length: 546 Bit Score: 46.41 E-value: 3.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1155 ESASAAVAVPTPEESASPAAAVPTPAESASFAAVVAtlEEPTSPAASVPTP----AAMVATLEEFTSPAASVPTSEEPAS 1230
Cdd:TIGR01348 74 EVGAGAQAQAEAKKEAAPAPTAGAPAPAAQAQAAPA--AGQSSGVQEVTVPdigdIEKVTVIEVLVKVGDTVSADQSLIT 151
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 1231 LAAAVSNPEEPTSPAAAVPTL------EEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTP 1303
Cdd:TIGR01348 152 LESDKASMEVPAPASGVVKSVkvkvgdSVPTGDLILTLSVAGSTPATAPAPASAQPAAQSPAATQPEPAAAPAAAKAQA 230
|
|
| DUF3729 |
pfam12526 |
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ... |
1230-1316 |
3.34e-04 |
|
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.
Pssm-ID: 372164 [Multi-domain] Cd Length: 115 Bit Score: 42.76 E-value: 3.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1230 SLAAAVSNPEEPTSPAAAVPTLEEPtSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEvaaiP 1309
Cdd:pfam12526 21 STSGFSSCFSPPESAHPDPPPPVGD-PRPPVVDTPPPVSAVWVLPPPSEPAAPEPDLVPPVTGPAGPPSPLAPPA----P 95
|
....*..
gi 2245149928 1310 AASVPTP 1316
Cdd:pfam12526 96 AQKPPLP 102
|
|
| ZipA |
COG3115 |
Cell division protein ZipA, interacts with FtsZ [Cell cycle control, cell division, chromosome ... |
1063-1168 |
3.41e-04 |
|
Cell division protein ZipA, interacts with FtsZ [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442349 [Multi-domain] Cd Length: 298 Bit Score: 45.84 E-value: 3.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1063 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSpAAAVPTPEEPTSPAAAVPTPEEPASPAAAV-PTPE----EPASPAAAV 1137
Cdd:COG3115 51 GEVRVVAAEAPERVEPEASFDAEDEVREPDQ-EEVDPLLDDEADIEAAPAEPVRWAGTAAAVePAPEqeayEEAGPAGES 129
|
90 100 110
....*....|....*....|....*....|.
gi 2245149928 1138 PTPEEPAFPAPAVPTPEESASAAVAVPTPEE 1168
Cdd:COG3115 130 AEQEDAPAEEPEAEAPAEEALAAELCAEPEE 160
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
1027-1159 |
3.46e-04 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 46.25 E-value: 3.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1027 TSPAAAvPPPEEPTSPAAAVPTPEEPTSPAAAVPTPeeptspaaaVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1106
Cdd:PRK12799 298 TVPVAA-VTPSSAVTQSSAITPSSAAIPSPAVIPSS---------VTTQSATTTQASAVALSSAGVLPSDVTLPGTVALP 367
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1107 PAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASA 1159
Cdd:PRK12799 368 AAEPVNMQPQPMSTTETQQSSTGNITSTANGPTTSLPAAPASNIPVSPTSRDA 420
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
1023-1149 |
3.55e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 46.31 E-value: 3.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1023 PEEPTSPA----AAVPPPEEPTSPAAAVPTPEEPTSPAAAvptpeePTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1098
Cdd:PRK14971 375 PKQHIKPVftqpAAAPQPSAAAAASPSPSQSSAAAQPSAP------QSATQPAGTPPTVSVDPPAAVPVNPPSTAPQAVR 448
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 2245149928 1099 PTPEEPTSPAAAVPTPEEpaspaaaVPTPEEPASPAAAVPTPEEPAFPAPA 1149
Cdd:PRK14971 449 PAQFKEEKKIPVSKVSSL-------GPSTLRPIQEKAEQATGNIKEAPTGT 492
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
2610-2953 |
3.69e-04 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 46.64 E-value: 3.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2610 EEHKVFANE--VNAHRDQIIELdQTGNQ---LKF---LSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAK 2681
Cdd:pfam05483 104 KENKLQENRkiIEAQRKAIQEL-QFENEkvsLKLeeeIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETR 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2682 Q----FHEAWKKLIDWLED----AE-SHLDSELEISNDPDKIKlqlSKHKEFQKTLGGKQP-----VYDTTIRTGRaLKE 2747
Cdd:pfam05483 183 QvymdLNNNIEKMILAFEElrvqAEnARLEMHFKLKEDHEKIQ---HLEEEYKKEINDKEKqvsllLIQITEKENK-MKD 258
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2748 KTLLPEDSQKLDNFLGEVRDKWDTVCGKSVERQHKLEE-------ALLFSGQFMDALQALVDWLYKVEPQLAEDQPVHgd 2820
Cdd:pfam05483 259 LTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKeledikmSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQ-- 336
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2821 LDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENSRDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQ---ALKQ 2897
Cdd:pfam05483 337 MEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEElkkILAE 416
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 2898 AEVFRD---TVHMLLEWLSEAEQTLRF----RGALPDDTEALQSLIDTHKE-FMKKVEEKRVDV 2953
Cdd:pfam05483 417 DEKLLDekkQFEKIAEELKGKEQELIFllqaREKEIHDLEIQLTAIKTSEEhYLKEVEDLKTEL 480
|
|
| PRK10905 |
PRK10905 |
cell division protein DamX; Validated |
1149-1316 |
3.82e-04 |
|
cell division protein DamX; Validated
Pssm-ID: 236792 [Multi-domain] Cd Length: 328 Bit Score: 45.70 E-value: 3.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1149 AVPTPEESASAAVAVPTPEE-SASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTP--------AAMVATLEefTSPA 1219
Cdd:PRK10905 51 VQPAPGTTSAEQTAGNTQQDvSLPPISSTPTQGQTPVATDGQQRVEVQGDLNNALTQPqnqqqlnnVAVNSTLP--TEPA 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1220 ASVPTSEEPASLAAAVSNPEE--PTSPAAAVPTLEEPTSSAAAVLTPEElssPAASVPTPEEPASPAAAVSnleEPASPA 1297
Cdd:PRK10905 129 TVAPVRNGNASRQTAKTQTAErpATTRPARKQAVIEPKKPQATAKTEPK---PVAQTPKRTEPAAPVASTK---APAATS 202
|
170 180
....*....|....*....|....*
gi 2245149928 1298 AAVPTPEVA------AIPAASVPTP 1316
Cdd:PRK10905 203 TPAPKETATtapvqtASPAQTTATP 227
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
963-1041 |
3.87e-04 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 45.83 E-value: 3.87e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 963 PITEEDGTPEGPVtpattvHAPEEPDTAAVRVSTPEEPASPAaavPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTS 1041
Cdd:PTZ00144 114 PLSEIDTGGAPPA------AAPAAAAAAKAEKTTPEKPKAAA---PTPEPPAASKPTPPAAAKPPEPAPAAKPPPTPVA 183
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
1014-1081 |
4.01e-04 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 45.83 E-value: 4.01e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 1014 TSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1081
Cdd:PTZ00144 120 TGGAPPAAAPAAAAAAKAEKTTPEKPKAAAPTPEPPAASKPTPPAAAKPPEPAPAAKPPPTPVARADP 187
|
|
| PPE |
COG5651 |
PPE-repeat protein [Function unknown]; |
1043-1271 |
4.09e-04 |
|
PPE-repeat protein [Function unknown];
Pssm-ID: 444372 [Multi-domain] Cd Length: 385 Bit Score: 45.65 E-value: 4.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1043 AAAV----PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP----TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1114
Cdd:COG5651 159 AAAValtpFTQPPPTITNPGGLLGAQNAGSGNTSSNPGFAnlglTGLNQVGIGGLNSGSGPIGLNSGPGNTGFAGTGAAA 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1115 EEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPeesaSPAAAVPTPAESASFAAVVATLEE 1194
Cdd:COG5651 239 GAAAAAAAAAAAAGAGASAALASLAATLLNASSLGLAATAASSAATNLGLAG----SPLGLAGGGAGAAAATGLGLGAGG 314
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1195 PTSPAASVPTPAAMVATLEEFTSPAASVPTSeepaslAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPA 1271
Cdd:COG5651 315 AAGAAGATGAGAALGAGAAAAAAGAAAGAGA------AAAAAAGGAGGGGGGALGAGGGGGSAGAAAGAASGGGAAA 385
|
|
| PRK10118 |
PRK10118 |
flagellar hook length control protein FliK; |
1095-1307 |
4.19e-04 |
|
flagellar hook length control protein FliK;
Pssm-ID: 236652 [Multi-domain] Cd Length: 408 Bit Score: 46.01 E-value: 4.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1095 AAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAA 1174
Cdd:PRK10118 57 AAGGKLSKGLLTTKGEPLVSDKLADLLAQQANLLIPVDETLPVITDEQSLSSPLTPALKTSALAALSKNAQKDEKADDLS 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1175 AVPTPAESASFAAVVATleePTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEP 1254
Cdd:PRK10118 137 DEDLASLSALFAMLPGQ---DNTTPVADAPSTVLPAEKPTLLTKDMPSAPQDETHTLSSDEHEKGLTSAQLTTAQPDDAP 213
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1255 TSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAA 1307
Cdd:PRK10118 214 GTPAQPLTPLAAEAQAKAEVISTPSPVTAAASPTITPHQTQPLPTAAAPVLSA 266
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
1004-1076 |
4.26e-04 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 45.83 E-value: 4.26e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1004 AAAVPTPEEPTSPAAAVPTPEEPTSPAaavPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1076
Cdd:PTZ00144 120 TGGAPPAAAPAAAAAAKAEKTTPEKPK---AAAPTPEPPAASKPTPPAAAKPPEPAPAAKPPPTPVARADPRE 189
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
1001-1122 |
4.29e-04 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 45.86 E-value: 4.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1001 ASPAAAVPTPEEPTSPAAavPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1080
Cdd:PRK12799 298 TVPVAAVTPSSAVTQSSA--ITPSSAAIPSPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVALPAAEPVNMQ 375
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 2245149928 1081 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAA 1122
Cdd:PRK12799 376 PQPMSTTETQQSSTGNITSTANGPTTSLPAAPASNIPVSPTS 417
|
|
| PRK12373 |
PRK12373 |
NADH-quinone oxidoreductase subunit E; |
1001-1123 |
4.35e-04 |
|
NADH-quinone oxidoreductase subunit E;
Pssm-ID: 237082 [Multi-domain] Cd Length: 400 Bit Score: 45.95 E-value: 4.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1001 ASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTpeepTSPAAAVPTPeEPTSPAAAVPTPEEPTS 1080
Cdd:PRK12373 208 ASKALAEDIGDTVKRIDGTEVPLLAPWQGDAAPVPPSEAARPKSADAE----TNAALKTPAT-APKAAAKNAKAPEAQPV 282
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 2245149928 1081 PAAAVPTPeeptSPAAAVPTPEEPTSPAAAV-PTPEEPASPAAA 1123
Cdd:PRK12373 283 SGTAAAEP----APKEAAKAAAAAAKPALEDkPRPLGIARPGGA 322
|
|
| PRK12373 |
PRK12373 |
NADH-quinone oxidoreductase subunit E; |
971-1110 |
4.39e-04 |
|
NADH-quinone oxidoreductase subunit E;
Pssm-ID: 237082 [Multi-domain] Cd Length: 400 Bit Score: 45.95 E-value: 4.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 971 PEGPVTPATTvHAPEEPDTAAVRVstpEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEP-TSPAAAVPTP 1049
Cdd:PRK12373 190 PAGGLTSLTE-EAGKARYNASKAL---AEDIGDTVKRIDGTEVPLLAPWQGDAAPVPPSEAARPKSADAeTNAALKTPAT 265
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1050 eEPTSPAAAVPTPEEPTSPAAAVPTPeeptSPAAAVPTPEEPTSPAAAV-PTPEEPTSPAAA 1110
Cdd:PRK12373 266 -APKAAAKNAKAPEAQPVSGTAAAEP----APKEAAKAAAAAAKPALEDkPRPLGIARPGGA 322
|
|
| PHA03309 |
PHA03309 |
transcriptional regulator ICP4; Provisional |
889-1205 |
4.44e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 165564 [Multi-domain] Cd Length: 2033 Bit Score: 46.39 E-value: 4.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 889 VSLEEEDVTAAAVSAPE---------RATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMS-------AVAGFS 952
Cdd:PHA03309 899 VTERREDLFSAARRCPRalyswersmRATTAALWGHLASRGPIAAPVADLEELSQALSAVLSVTSVPdggdvryAFAEAD 978
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 953 PEWAALAITVPiteedgtpEGPVTPATTVHAPEEPDtAAVRVSTPEEPASPAAAVPT--PEEPTSPAAAVPTPEEPTSPA 1030
Cdd:PHA03309 979 EGWRALAVMLG--------GGAVRTSSGESGDAETD-AAYALLAPGKQSSAGVNHPRgrPGRATASSPRTPASRPPHGSA 1049
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1031 AAvpPPEEPTSPAAAVPTPEeptspaaavpTPEEPTSPAAAVPTPEEPTSPAAAvpTPEEPTSPaaAVPTPEEPTSPaaa 1110
Cdd:PHA03309 1050 AA--PPSGRDSPPGALNVPE----------AAEEELRLAAARDTTGDLLSDEAG--TDDDGDAP--VVISYVGPSSP--- 1110
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1111 vPTPEEPASPAAAVPTPeepaSPAAAVPTPEEPAFPAPAVPTPEESASAavavPTPEESASPAAAVPTPAESASFAAVVA 1190
Cdd:PHA03309 1111 -PGVEDPSPDGLAALRP----LPEGYVPRPGDVLRGDPGADENDDDARA----PCRVGDASPPRQLPSSSSFASSSLASA 1181
|
330
....*....|....*
gi 2245149928 1191 TLEEPTSPaASVPTP 1205
Cdd:PHA03309 1182 VPGDPYLP-RSVAEP 1195
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
1028-1089 |
4.52e-04 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 46.15 E-value: 4.52e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1028 SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1089
Cdd:COG5373 44 ASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEAEPAAAPAAAS 105
|
|
| half-pint |
TIGR01645 |
poly-U binding splicing factor, half-pint family; The proteins represented by this model ... |
971-1136 |
4.58e-04 |
|
poly-U binding splicing factor, half-pint family; The proteins represented by this model contain three RNA recognition motifs (rrm: pfam00076) and have been characterized as poly-pyrimidine tract binding proteins associated with RNA splicing factors. In the case of PUF60 (GP|6176532), in complex with p54, and in the presence of U2AF, facilitates association of U2 snRNP with pre-mRNA.
Pssm-ID: 130706 [Multi-domain] Cd Length: 612 Bit Score: 46.22 E-value: 4.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 971 PEGPVTPATTVHAPEEPDTAAV----RVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEP---TSPAAAVPPPEEPTSPA 1043
Cdd:TIGR01645 285 PDALLQPATVSAIPAAAAVAAAaataKIMAAEAVAGAAVLGPRAQSPATPSSSLPTDIGNkavVSSAKKEAEEVPPLPQA 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1044 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAA 1123
Cdd:TIGR01645 365 APAVVKPGPMEIPTPVPPPGLAIPSLVAPPGLVAPTEINPSFLASPRKKMKREKLPVTFGALDDTLAWKEPSKEDQTSED 444
|
170
....*....|...
gi 2245149928 1124 VPTPEEPASPAAA 1136
Cdd:TIGR01645 445 GKMLAIMGEAAAA 457
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
949-1046 |
4.65e-04 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 46.42 E-value: 4.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 949 AGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTS 1028
Cdd:PRK12270 34 ADYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAV 113
|
90
....*....|....*...
gi 2245149928 1029 PAAAVPppeePTSPAAAV 1046
Cdd:PRK12270 114 EDEVTP----LRGAAAAV 127
|
|
| PRK13042 |
PRK13042 |
superantigen-like protein SSL4; Reviewed; |
1014-1104 |
4.68e-04 |
|
superantigen-like protein SSL4; Reviewed;
Pssm-ID: 183854 [Multi-domain] Cd Length: 291 Bit Score: 45.39 E-value: 4.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1014 TSPAAAVPTPEEPTSPAAAVPPPEepTSPAAAVPTPEEPTSPAAAVPTPEeptspaaavPTPEEPTSPAAAVPTPEEPTS 1093
Cdd:PRK13042 24 TTQAANATTPSSTKVEAPQSTPPS--TKVEAPQSKPNATTPPSTKVEAPQ---------QTPNATTPSSTKVETPQSPTT 92
|
90
....*....|.
gi 2245149928 1094 paAAVPTPEEP 1104
Cdd:PRK13042 93 --KQVPTEINP 101
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
1077-1259 |
4.69e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 45.89 E-value: 4.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1077 EPTSPAAAVPTPEEPTSPAAAVPTPEeptspAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEES 1156
Cdd:PRK14965 378 ERGAPAPPSAAWGAPTPAAPAAPPPA-----AAPPVPPAAPARPAAARPAPAPAPPAAAAPPARSADPAAAASAGDRWRA 452
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1157 ASAAVavptpeESASPAAAvpTPAESASFAAVVATLEEPTSPAASVP--------TPAAMVATLEEFTSPAASV------ 1222
Cdd:PRK14965 453 FVAFV------KGKKPALG--ASLEQGSPLGVSAGLLEIGFPEGSFElsamqdpdSRAELKALAEQFFGRPTRLritvla 524
|
170 180 190
....*....|....*....|....*....|....*...
gi 2245149928 1223 -PTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAA 1259
Cdd:PRK14965 525 aPPGAAPPSLAEKKAAEREQRQARLREEAREHPLVQEA 562
|
|
| PHA03169 |
PHA03169 |
hypothetical protein; Provisional |
1050-1203 |
4.71e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 45.73 E-value: 4.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1050 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAaavptPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEE 1129
Cdd:PHA03169 126 SSPESPASHSPPPSPPSHPGPHEPAPPESHNPS-----PNQQPSSFLQPSHEDSPEEPEPPTSEPEPDSPGPPQSETPTS 200
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 1130 PASPAAAvptPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATlEEPTSPAASVP 1203
Cdd:PHA03169 201 SPPPQSP---PDEPGEPQSPTPQQAPSPNTQQAVEHEDEPTEPEREGPPFPGHRSHSYTVVG-WKPSTRPGGVP 270
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
1105-1172 |
4.85e-04 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 45.83 E-value: 4.85e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 1105 TSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASP 1172
Cdd:PTZ00144 120 TGGAPPAAAPAAAAAAKAEKTTPEKPKAAAPTPEPPAASKPTPPAAAKPPEPAPAAKPPPTPVARADP 187
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
985-1125 |
4.88e-04 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 45.86 E-value: 4.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 985 EEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEepTSPAAAVPTPEEPTSpAAAVPTPEE 1064
Cdd:PRK12799 275 ENLDNRALDIEKATGLKQIDTHGTVPVAAVTPSSAVTQSSAITPSSAAIPSPA--VIPSSVTTQSATTTQ-ASAVALSSA 351
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2245149928 1065 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVP 1125
Cdd:PRK12799 352 GVLPSDVTLPGTVALPAAEPVNMQPQPMSTTETQQSSTGNITSTANGPTTSLPAAPASNIP 412
|
|
| PPE |
COG5651 |
PPE-repeat protein [Function unknown]; |
1001-1235 |
4.95e-04 |
|
PPE-repeat protein [Function unknown];
Pssm-ID: 444372 [Multi-domain] Cd Length: 385 Bit Score: 45.65 E-value: 4.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1001 ASPAAAVptpeeptspAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEP----TSPAAAVPTPEEPTSPAAAVPTPE 1076
Cdd:COG5651 156 AASAAAV---------ALTPFTQPPPTITNPGGLLGAQNAGSGNTSSNPGFAnlglTGLNQVGIGGLNSGSGPIGLNSGP 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1077 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEES 1156
Cdd:COG5651 227 GNTGFAGTGAAAGAAAAAAAAAAAAGAGASAALASLAATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAAAT 306
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 1157 ASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAV 1235
Cdd:COG5651 307 GLGLGAGGAAGAAGATGAGAALGAGAAAAAAGAAAGAGAAAAAAAGGAGGGGGGALGAGGGGGSAGAAAGAASGGGAAA 385
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1614-2239 |
4.99e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 46.21 E-value: 4.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1614 AKIQQQIIRHKALNEEIVNRKKNVDQAIKNGQALLKQTTgEEVLLIQEKLDGIKTRYADItvtsSKALRTLEQARQLATK 1693
Cdd:PRK03918 168 GEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVL-REINEISSELPELREELEKL----EKEVKELEELKEEIEE 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1694 FQSTYEELTGWLREVEEelatsggqsptgeQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVpwRAREGLDKLVS 1773
Cdd:PRK03918 243 LEKELESLEGSKRKLEE-------------KIRELEERIEELKKEIEELEEKVKELKELKEKAEEYI--KLSEFYEEYLD 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1774 DANEQYKLVSDtIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPiRLEQDQTTAQLQVQKAfsidiiRHKD 1853
Cdd:PRK03918 308 ELREIEKRLSR-LEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEE-RHELYEEAKAKKEELE------RLKK 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1854 SMDELFSHRSEIFGTCGEEQKTVLQEKTESLIQQyeaISLLNSERyARLERAqvlVNQFWE------------TYEELSP 1921
Cdd:PRK03918 380 RLTGLTPEKLEKELEELEKAKEEIEEEISKITAR---IGELKKEI-KELKKA---IEELKKakgkcpvcgrelTEEHRKE 452
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1922 WIEETRALIAQLPSPAID-HEQLRQQQEEMRQLrESIAEHKPHIDKLLKIGPQLKELNPEEGEMVEEKYQKAENMYaqik 2000
Cdd:PRK03918 453 LLEEYTAELKRIEKELKEiEEKERKLRKELREL-EKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEY---- 527
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2001 EEVRQRALALDEAVSqstqitefhdKIEPMLETLENLSSRLRmppLIPAEVDKIRECISDNKSatvELEKLQ-PSFEALK 2079
Cdd:PRK03918 528 EKLKEKLIKLKGEIK----------SLKKELEKLEELKKKLA---ELEKKLDELEEELAELLK---ELEELGfESVEELE 591
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2080 RRGEELigrSQGADKDLAAKEIQDKLdqmvffwedikaRAEEREIKFLDvLELAEKFwydmaallttiKDTQDIVHDLES 2159
Cdd:PRK03918 592 ERLKEL---EPFYNEYLELKDAEKEL------------EREEKELKKLE-EELDKAF-----------EELAETEKRLEE 644
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2160 pgidpsiIKQQVEAAETI--KEETDGLHEELEFIRILGADLifacgETEKPEVRKSIDEMNNAWENLN------KTWKER 2231
Cdd:PRK03918 645 -------LRKELEELEKKysEEEYEELREEYLELSRELAGL-----RAELEELEKRREEIKKTLEKLKeeleerEKAKKE 712
|
....*...
gi 2245149928 2232 LEKLEDAM 2239
Cdd:PRK03918 713 LEKLEKAL 720
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
1015-1076 |
5.00e-04 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 46.15 E-value: 5.00e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1015 SPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1076
Cdd:COG5373 44 ASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEAEPAAAPAAAS 105
|
|
| PRK15313 |
PRK15313 |
intestinal colonization autotransporter adhesin MisL; |
1036-1120 |
5.15e-04 |
|
intestinal colonization autotransporter adhesin MisL;
Pssm-ID: 237940 [Multi-domain] Cd Length: 955 Bit Score: 45.95 E-value: 5.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1036 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPtpeEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPaaavPTPE 1115
Cdd:PRK15313 560 PDEPIIPDPVDPVIPDPVIPDPVDPDPVDPVIPDPVIP---DPVDPDPVDPEPVDPVIPDPTIPDIGQSDTP----PITE 632
|
....*
gi 2245149928 1116 EPASP 1120
Cdd:PRK15313 633 HQFRP 637
|
|
| Cornifin |
pfam02389 |
Cornifin (SPRR) family; SPRR genes (formerly SPR) encode a novel class of polypeptides (small ... |
960-1075 |
5.46e-04 |
|
Cornifin (SPRR) family; SPRR genes (formerly SPR) encode a novel class of polypeptides (small proline rich proteins) that are strongly induced during differentiation of human epidermal keratinocytes in vitro and in vivo. The most characteriztic feature of the SPRR gene family resides in the structure of the central segments of the encoded polypeptides that are built up from tandemly repeated units of either eight (SPRR1 and SPRR3) or nine (SPRR2) amino acids with the general consensus XKXPEPXX where X is any amino acid. In order to avoid bacterial contamination due to the high polar-nature of the HMM the threshold has been set very high.
Pssm-ID: 280537 [Multi-domain] Cd Length: 135 Bit Score: 42.73 E-value: 5.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 960 ITVPITEEDGTPEGPvTPATTvHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPaaAVPPPEEP 1039
Cdd:pfam02389 16 PCVPTTKEPCHSKVP-EPCNP-KVPEPCCPKVPEPCCPKVPEPCCPKVPEPCCPKVPEPCYPKVPEPCSP--KVPEPCHP 91
|
90 100 110
....*....|....*....|....*....|....*....
gi 2245149928 1040 TSP---AAAVPTPEEPTSPAAAVPTPEEPTsPAAAVPTP 1075
Cdd:pfam02389 92 KAPepcHPKVPEPCYPKAPEPCQPKVPEPC-PSTVTPGP 129
|
|
| PTZ00436 |
PTZ00436 |
60S ribosomal protein L19-like protein; Provisional |
1159-1316 |
5.68e-04 |
|
60S ribosomal protein L19-like protein; Provisional
Pssm-ID: 185616 [Multi-domain] Cd Length: 357 Bit Score: 45.33 E-value: 5.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1159 AAVAVPTPEESASPAAAVPTPAESASFAAvvatleeptsPAASVPTPAAMVATLEEFTSPAASVPTSeePASLAAAVSNP 1238
Cdd:PTZ00436 193 AAAAAAAKQKAAAKKAAAPSGKKSAKAAA----------PAKAAAAPAKAAAPPAKAAAAPAKAAAA--PAKAAAPPAKA 260
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 1239 EEPTSPAAAVPtleeptssAAAVLTPEELSSPAASVPTPeePASPAAAVSNLEEPASPAAAVPTpEVAAIPAASVPTP 1316
Cdd:PTZ00436 261 AAPPAKAAAPP--------AKAAAPPAKAAAPPAKAAAP--PAKAAAAPAKAAAAPAKAAAAPA-KAAAPPAKAAAPP 327
|
|
| PRK15313 |
PRK15313 |
intestinal colonization autotransporter adhesin MisL; |
1010-1094 |
5.70e-04 |
|
intestinal colonization autotransporter adhesin MisL;
Pssm-ID: 237940 [Multi-domain] Cd Length: 955 Bit Score: 45.95 E-value: 5.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1010 PEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPtpeEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPaaavPTPE 1089
Cdd:PRK15313 560 PDEPIIPDPVDPVIPDPVIPDPVDPDPVDPVIPDPVIP---DPVDPDPVDPEPVDPVIPDPTIPDIGQSDTP----PITE 632
|
....*
gi 2245149928 1090 EPTSP 1094
Cdd:PRK15313 633 HQFRP 637
|
|
| PHA03381 |
PHA03381 |
tegument protein VP22; Provisional |
1051-1200 |
5.79e-04 |
|
tegument protein VP22; Provisional
Pssm-ID: 177618 [Multi-domain] Cd Length: 290 Bit Score: 45.00 E-value: 5.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1051 EPTSPAA--AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT--------PEEPTSPAAAVPTPEEPA-S 1119
Cdd:PHA03381 24 DFISPDAspARVSFEEPADRARRGAGQARGRSQAERRFHHYDEARADYPYYTgsssederPADPRPSRRPHAQPEASGpG 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1120 PAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAvptPAESASFAAVVATLE---EPT 1196
Cdd:PHA03381 104 PARGARGPAGSRGRGRRAESPSPRDPPNPKGASAPRGRKSACADSAALLDAPAPAA---PKRQKTPAGLARKLHfstAPT 180
|
....
gi 2245149928 1197 SPAA 1200
Cdd:PHA03381 181 SPTA 184
|
|
| PHA01929 |
PHA01929 |
putative scaffolding protein |
1000-1076 |
5.98e-04 |
|
putative scaffolding protein
Pssm-ID: 177328 Cd Length: 306 Bit Score: 45.05 E-value: 5.98e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 1000 PASPAAAVPTPEEPTSPA-AAVPTPEEPTSPAAAVPPPEEPTSPAAavPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1076
Cdd:PHA01929 31 PVIQPQAPVQPGQPGAPQqLAIPTQQPQPVPTSAMTPHVVQQAPAQ--PAPAAPPAAGAALPEALEVPPPPAFTPNGE 106
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
1106-1204 |
5.98e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 45.83 E-value: 5.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1106 SPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAV----AVPTPEES---ASPAAAVP- 1177
Cdd:PRK14959 379 SAPSGSAAEGPASGGAATIPTPGTQGPQGTAPAAGMTPSSAAPATPAPSAAPSPRVpwddAPPAPPRSgipPRPAPRMPe 458
|
90 100 110
....*....|....*....|....*....|...
gi 2245149928 1178 ------TPAESASFAAVVATLEEPTSPAASVPT 1204
Cdd:PRK14959 459 aspvpgAPDSVASASDAPPTLGDPSDTAEHTPS 491
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
2022-2125 |
5.98e-04 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 41.55 E-value: 5.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2022 EFHDKIEPMLETLENLSSRLRMPPlIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIgrsqgADKDLAAKEI 2101
Cdd:smart00150 2 QFLRDADELEAWLEEKEQLLASED-LGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLI-----EEGHPDAEEI 75
|
90 100
....*....|....*....|....
gi 2245149928 2102 QDKLDQMVFFWEDIKARAEEREIK 2125
Cdd:smart00150 76 EERLEELNERWEELKELAEERRQK 99
|
|
| PRK15313 |
PRK15313 |
intestinal colonization autotransporter adhesin MisL; |
997-1081 |
6.00e-04 |
|
intestinal colonization autotransporter adhesin MisL;
Pssm-ID: 237940 [Multi-domain] Cd Length: 955 Bit Score: 45.95 E-value: 6.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 997 PEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPppeEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPaaavPTPE 1076
Cdd:PRK15313 560 PDEPIIPDPVDPVIPDPVIPDPVDPDPVDPVIPDPVIP---DPVDPDPVDPEPVDPVIPDPTIPDIGQSDTP----PITE 632
|
....*
gi 2245149928 1077 EPTSP 1081
Cdd:PRK15313 633 HQFRP 637
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
1941-2373 |
6.05e-04 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 45.60 E-value: 6.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1941 EQLRQQQEEMRQLRESIAEHKPHIDKLLKI---------------GP-------QLKELNPEEGEMVEEK----YQKAEN 1994
Cdd:PRK04778 119 EDIEQILEELQELLESEEKNREEVEQLKDLyrelrksllanrfsfGPaldelekQLENLEEEFSQFVELTesgdYVEARE 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1995 MYAQIKEEVrqralaldeavsqsTQITEFHDKIEPMLETLEN--------LSSRLR--------MPPL-IPAEVDKIREC 2057
Cdd:PRK04778 199 ILDQLEEEL--------------AALEQIMEEIPELLKELQTelpdqlqeLKAGYRelveegyhLDHLdIEKEIQDLKEQ 264
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2058 ISDNKSATVELEklqpsfeaLKRRGEELigrsqgadkdlaaKEIQDKLDQM--VFfwedikaraeEREIKfldvlelAEK 2135
Cdd:PRK04778 265 IDENLALLEELD--------LDEAEEKN-------------EEIQERIDQLydIL----------EREVK-------ARK 306
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2136 FwydmaallttIKDTQDIVhdlespgidPSIIKQQVEAAETIKEETDGL-------HEELEFIRILGADLifacgetekP 2208
Cdd:PRK04778 307 Y----------VEKNSDTL---------PDFLEHAKEQNKELKEEIDRVkqsytlnESELESVRQLEKQL---------E 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2209 EVRKSIDEMNNAWENLNKTW---KERLEKLEDAMQAA----VQYQDTLQAMFDwldntviklctmppvgtDLNTVKDQLN 2281
Cdd:PRK04778 359 SLEKQYDEITERIAEQEIAYselQEELEEILKQLEEIekeqEKLSEMLQGLRK-----------------DELEAREKLE 421
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2282 EMKEFKVEVYQQqieMEKLNHQG-----ELMLKKATDetdrdiirepltELKHLWENLGEK---IAHRQHKLEGALLALG 2353
Cdd:PRK04778 422 RYRNKLHEIKRY---LEKSNLPGlpedyLEMFFEVSD------------EIEALAEELEEKpinMEAVNRLLEEATEDVE 486
|
490 500
....*....|....*....|
gi 2245149928 2354 QFQHALEELMSWLTHTEELL 2373
Cdd:PRK04778 487 TLEEETEELVENATLTEQLI 506
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
1041-1102 |
6.12e-04 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 45.76 E-value: 6.12e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1041 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1102
Cdd:COG5373 44 ASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEAEPAAAPAAAS 105
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
1798-1904 |
6.18e-04 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 41.92 E-value: 6.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1798 QRSQQYEQAADAELAWVAETKRKLMAlGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFsHRSEIFGTCGEEQKTVL 1877
Cdd:pfam00435 1 LLLQQFFRDADDLESWIEEKEALLSS-EDYGKDLESVQALLKKHKALEAELAAHQDRVEALN-ELAEKLIDEGHYASEEI 78
|
90 100
....*....|....*....|....*..
gi 2245149928 1878 QEKTESLIQQYEAISLLNSERYARLER 1904
Cdd:pfam00435 79 QERLEELNERWEQLLELAAERKQKLEE 105
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1871-2364 |
6.21e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.53 E-value: 6.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1871 EEQKTVLQEKTESLIQQYEAISLLNsERYARLERAQVLVNQ---FWETYEELSPWIEETRALIAQLPSPAIDHEQLRQQQ 1947
Cdd:COG4717 77 EEELKEAEEKEEEYAELQEELEELE-EELEELEAELEELREeleKLEKLLQLLPLYQELEALEAELAELPERLEELEERL 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1948 EEMRQLRESIAEHKPHIDKLLKigpQLKELNPEEGEMVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKI 2027
Cdd:COG4717 156 EELRELEEELEELEAELAELQE---ELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2028 EPMLETLENLSSRLRMPPLIPAEvdkirecisdnkSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQ 2107
Cdd:COG4717 233 ENELEAAALEERLKEARLLLLIA------------AALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASL 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2108 MVFFwEDIKARAEEREIKFLDVLELAEKFWYDMAALLTTIKDTQDIVHDLespgidpsiiKQQVEAAETIKEETDGLHEE 2187
Cdd:COG4717 301 GKEA-EELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEEL----------QELLREAEELEEELQLEELE 369
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2188 LEFIRILGadlifACGETEKPEVRKSIDEMNNAwenlnKTWKERLEKLEDAMQAAvqyqdtLQAMFDWLDNtviklctmp 2267
Cdd:COG4717 370 QEIAALLA-----EAGVEDEEELRAALEQAEEY-----QELKEELEELEEQLEEL------LGELEELLEA--------- 424
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2268 pvgTDLNTVKDQLNEMKEfKVEVYQQQIEmEKLNHQGELMLKKATDETDRDiirepLTELKHLWENLGEKIAHRQHKLEG 2347
Cdd:COG4717 425 ---LDEEELEEELEELEE-ELEELEEELE-ELREELAELEAELEQLEEDGE-----LAELLQELEELKAELRELAEEWAA 494
|
490
....*....|....*..
gi 2245149928 2348 ALLALGQFQHALEELMS 2364
Cdd:COG4717 495 LKLALELLEEAREEYRE 511
|
|
| PHA02030 |
PHA02030 |
hypothetical protein |
1000-1070 |
6.21e-04 |
|
hypothetical protein
Pssm-ID: 222843 [Multi-domain] Cd Length: 336 Bit Score: 44.97 E-value: 6.21e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2245149928 1000 PASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPtPEEPTSPAAAVPTPEEPTSPAA 1070
Cdd:PHA02030 264 SNLPAVPNVAADAGSAAAPAVPAAAAAVAQAAPSVPQVPNVAVLPDVP-QVAPVAAPAAPEVPAVPVVPAA 333
|
|
| PRK12373 |
PRK12373 |
NADH-quinone oxidoreductase subunit E; |
1035-1175 |
6.30e-04 |
|
NADH-quinone oxidoreductase subunit E;
Pssm-ID: 237082 [Multi-domain] Cd Length: 400 Bit Score: 45.18 E-value: 6.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1035 PPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTpeepTSPAAAVPTP 1114
Cdd:PRK12373 190 PAGGLTSLTEEAGKARYNASKALAEDIGDTVKRIDGTEVPLLAPWQGDAAPVPPSEAARPKSADAE----TNAALKTPAT 265
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2245149928 1115 EePASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAvavPTPEESASPAAA 1175
Cdd:PRK12373 266 A-PKAAAKNAKAPEAQPVSGTAAAEPAPKEAAKAAAAAAKPALEDK---PRPLGIARPGGA 322
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
983-1039 |
6.33e-04 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 45.76 E-value: 6.33e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 983 APEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAvPPPEEP 1039
Cdd:COG5373 46 APAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEA-EPAAAP 101
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
1190-1310 |
6.40e-04 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 45.65 E-value: 6.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1190 ATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSS 1269
Cdd:PRK12270 34 ADYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAV 113
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 2245149928 1270 PAASVPTpeepASPAAAV-SNLEEPASpaaaVPTP-EVAAIPA 1310
Cdd:PRK12270 114 EDEVTPL----RGAAAAVaKNMDASLE----VPTAtSVRAVPA 148
|
|
| KREPA2 |
cd23959 |
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of ... |
972-1106 |
6.45e-04 |
|
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of the parasitic protozoan's KREPA RNA editing catalytic complex (RECC). Kinetoplastid RNA editing (KRE) proteins occur as pairs or sets of related proteins in multiple complexes. KREPA complex is composed of six components (KREPA1-6), which share a conserved C-terminal region containing an oligonucleotide-binding (OB)-fold-like domain. KREPAs are responsible for the site-specific insertion and deletion of U nucleotides in the kinetoplastid mitochondria pre-messenger RNA. Apart from the conserved C-terminal OB-fold domain, KREPA1, KREPA2, and KREPA3 contain two conserved C2H2 zinc-finger domains. KREPA2 and kinetoplastid RNA editing ligase 1 (KREL1) are specific for ligation post-U-deletion and are paralogous to KREL2 and KREPA1 that are specific for ligation post-U-insertion. KREPA2, is critical for RECC stability and KREL1 integration into the complex.
Pssm-ID: 467780 [Multi-domain] Cd Length: 424 Bit Score: 45.24 E-value: 6.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 972 EGPVTPATTVHAPEEPDTAAVRvstpEEPASPAAAVPTPEEpTSPAAAVPTPEEPTSPAAAvpPPEEPTSPAAAVPTPEE 1051
Cdd:cd23959 122 SSSTQRETHKTAQVAPPKAEPQ----TAPVTPFGQLPMFGQ-HPPPAKPLPAAAAAQQSSA--SPGEVASPFASGTVSAS 194
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1052 PTSPAAAV-PTPEEPTSPAAAVPTPeeptSPAAAVPTPEepTSPAAAVPTPEEPTS 1106
Cdd:cd23959 195 PFATATDTaPSSGAPDGFPAEASAP----SPFAAPASAA--SFPAAPVANGEAATP 244
|
|
| motB |
PRK05996 |
MotB family protein; |
1018-1167 |
6.48e-04 |
|
MotB family protein;
Pssm-ID: 235665 [Multi-domain] Cd Length: 423 Bit Score: 45.46 E-value: 6.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1018 AAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEeptspaAAVPTPEEPTSPAAAVpTPEEPTSPAAAVPTPEEPTSPAAA 1097
Cdd:PRK05996 162 AAQSGPATGADGGEAYRDPFDPDFWSKQVEVTT------AGDLLPPGQAREQAQG-AKSATAAPATVPQAAPLPQAQPKK 234
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1098 VPTPEEPTSPAAAVPTPEEPASPAAAvPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPE 1167
Cdd:PRK05996 235 AATEEELIADAKKAATGEPAANAAKA-AKPEPMPDDQQKEAEQLQAAIAQAIGGVAGKLAEGVTVTPVEG 303
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
995-1109 |
6.54e-04 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 45.09 E-value: 6.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 995 STPEEPASPAAAVPTPEEPTSPAAAVPTPEepTSPAAAVPPPEEPTS-PAAAVPTPEEPTSPAAAVPTPEEP-TSPAAAV 1072
Cdd:PRK12799 298 TVPVAAVTPSSAVTQSSAITPSSAAIPSPA--VIPSSVTTQSATTTQaSAVALSSAGVLPSDVTLPGTVALPaAEPVNMQ 375
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 2245149928 1073 PTPEEPT-----SPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1109
Cdd:PRK12799 376 PQPMSTTetqqsSTGNITSTANGPTTSLPAAPASNIPVSPTS 417
|
|
| PLN02983 |
PLN02983 |
biotin carboxyl carrier protein of acetyl-CoA carboxylase |
995-1139 |
6.55e-04 |
|
biotin carboxyl carrier protein of acetyl-CoA carboxylase
Pssm-ID: 215533 [Multi-domain] Cd Length: 274 Bit Score: 44.44 E-value: 6.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 995 STPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAA-----AVPTPEEPTSPAAAVPTPEEPTSPA 1069
Cdd:PLN02983 3 SLSVPCAKTAAAAANVGSRLSRSSFRLQPKPNISFPSKGPNPKRSAVPKVkaqlnEVAVDGSSNSAKSDDPKSEVAPSEP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1070 AAVPTPEEPTSPAaaVPTPEE----------------------------------------PTSPAAAVPTPEEPTSPAA 1109
Cdd:PLN02983 83 KDEPPSNSSSKPN--LPDEESisefmtqvsslvklvdsrdivelqlkqldcelvirkkealPQPPPPAPVVMMQPPPPHA 160
|
170 180 190
....*....|....*....|....*....|
gi 2245149928 1110 AVPTPEEPASPAAAVPTPEEPASPAAAVPT 1139
Cdd:PLN02983 161 MPPASPPAAQPAPSAPASSPPPTPASPPPA 190
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
1801-1903 |
6.59e-04 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 41.55 E-value: 6.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1801 QQYEQAADAELAWVAETKRKLMALGPIRLEqDQTTAQLQVQKAFSIDIIRHKDSMDELfSHRSEIFGTCGEEQKTVLQEK 1880
Cdd:smart00150 1 QQFLRDADELEAWLEEKEQLLASEDLGKDL-ESVEALLKKHEAFEAELEAHEERVEAL-NELGEQLIEEGHPDAEEIEER 78
|
90 100
....*....|....*....|...
gi 2245149928 1881 TESLIQQYEAISLLNSERYARLE 1903
Cdd:smart00150 79 LEELNERWEELKELAEERRQKLE 101
|
|
| PPE |
COG5651 |
PPE-repeat protein [Function unknown]; |
1095-1316 |
6.70e-04 |
|
PPE-repeat protein [Function unknown];
Pssm-ID: 444372 [Multi-domain] Cd Length: 385 Bit Score: 45.27 E-value: 6.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1095 AAAV----PTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESA 1170
Cdd:COG5651 159 AAAValtpFTQPPPTITNPGGLLGAQNAGSGNTSSNPGFANLGLTGLNQVGIGGLNSGSGPIGLNSGPGNTGFAGTGAAA 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1171 SPAAAVPTPAESASFAAVVAtleePTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPT 1250
Cdd:COG5651 239 GAAAAAAAAAAAAGAGASAA----LASLAATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAAATGLGLGAGG 314
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1251 LEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTP 1316
Cdd:COG5651 315 AAGAAGATGAGAALGAGAAAAAAGAAAGAGAAAAAAAGGAGGGGGGALGAGGGGGSAGAAAGAASG 380
|
|
| motB |
PRK05996 |
MotB family protein; |
939-1194 |
6.76e-04 |
|
MotB family protein;
Pssm-ID: 235665 [Multi-domain] Cd Length: 423 Bit Score: 45.07 E-value: 6.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 939 AITQEGMSAVAG-FSPewaalaitVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAA---VPTPEEPT 1014
Cdd:PRK05996 55 AANEETKAAVASyFNP--------IKLTDRKPSEKGLKDPVDGAEGEQKPGKSKFEEDQRVEGSSAVTGddtTRTSGDQT 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1015 SPAAAV--PTPEEPTSPAAAVPPPEEPTSPA----AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEeptspaAAVPTP 1088
Cdd:PRK05996 127 NYSEADlfRNPYAVLAEIAQEVGQQANVSAKgdggAAQSGPATGADGGEAYRDPFDPDFWSKQVEVTT------AGDLLP 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1089 EEPTSPAAAVpTPEEPTSPAAAvPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAvPTPEE 1168
Cdd:PRK05996 201 PGQAREQAQG-AKSATAAPATV-PQAAPLPQAQPKKAATEEELIADAKKAATGEPAANAAKAAKPEPMPDDQQK-EAEQL 277
|
250 260
....*....|....*....|....*.
gi 2245149928 1169 SASPAAAVPTPAESASFAAVVATLEE 1194
Cdd:PRK05996 278 QAAIAQAIGGVAGKLAEGVTVTPVEG 303
|
|
| PHA03169 |
PHA03169 |
hypothetical protein; Provisional |
1102-1301 |
7.12e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 44.96 E-value: 7.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1102 EEPTSPAAAVPTPEEPASPAAAvpTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASaavavPTPEESASPAAAvPTPAE 1181
Cdd:PHA03169 102 SPTPSPSGSAEELASGLSPENT--SGSSPESPASHSPPPSPPSHPGPHEPAPPESHN-----PSPNQQPSSFLQ-PSHED 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1182 SAsfaavvatleEPTSPAASVPTPaamvatleeftsPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAV 1261
Cdd:PHA03169 174 SP----------EEPEPPTSEPEP------------DSPGPPQSETPTSSPPPQSPPDEPGEPQSPTPQQAPSPNTQQAV 231
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 2245149928 1262 LTPEELSSPAASVPTPEEPASPAAAVSNlEEPASPAAAVP 1301
Cdd:PHA03169 232 EHEDEPTEPEREGPPFPGHRSHSYTVVG-WKPSTRPGGVP 270
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
1195-1316 |
7.23e-04 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 44.76 E-value: 7.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1195 PTSPAASVPTPA--AMVATLEEFTSPAASVPT----SEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELS 1268
Cdd:NF040712 195 PLRPLATVPRLArePADARPEEVEPAPAAEGApatdSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPDEAT 274
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2245149928 1269 SPAASVPTPEEPASPAAAVSNLEEPASPAA-AVPTPEVAAIPAASVPTP 1316
Cdd:NF040712 275 RDAGEPPAPGAAETPEAAEPPAPAPAAPAApAAPEAEEPARPEPPPAPK 323
|
|
| DedD |
COG3147 |
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, ... |
1035-1102 |
7.28e-04 |
|
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442381 [Multi-domain] Cd Length: 140 Bit Score: 42.45 E-value: 7.28e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 1035 PPEEPTSPAAAVPTPEEPtsPAAAVPTPEEPTSPAAAVPTPeeptSPAAAVPTPEEPTSPAAAVPTPE 1102
Cdd:COG3147 1 PAEEAAAAPAAAAAPAAP--AAAAAPAPAAAAAAAAPKPAA----KPAAPKPAAAAAAAPAAKAAAPA 62
|
|
| KLF14_N |
cd21576 |
N-terminal domain of Kruppel-like factor 14; Kruppel-like factor 14 (KLF14; also known as ... |
1034-1200 |
7.35e-04 |
|
N-terminal domain of Kruppel-like factor 14; Kruppel-like factor 14 (KLF14; also known as Krueppel-like factor 14 or basic transcription element-binding protein 5/BTEB5) is a protein that in humans is encoded by the KLF14 gene. KLF14 regulates the transcription of various genes, including TGFbetaRII (the type II receptor for TGFbeta). KLF14 is expressed in many tissues, lacks introns, and is subject to parent-specific expression. It also appears to be a master regulator of gene expression in adipose tissue. KLF14 is associated with coronary artery disease, hypercholesterolemia, and type 2 diabetes. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. KLF14 belongs to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the N-terminal domain of KLF14.
Pssm-ID: 409238 [Multi-domain] Cd Length: 195 Bit Score: 43.66 E-value: 7.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1034 PPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS--PAAAVPTPEEPTSPAAavptpeePTSPAAAVPTPEEPTSPAAAV 1111
Cdd:cd21576 28 APDPEGAGGAAGSEVGAAPPESALPGPGPPGPAWvpPLLQVPAPSPGAGGAA-------PHLLAASVLADLRGGAGEGSR 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1112 PTPEEpaSPAAAVPTPEePASPAAAVPTPEE-PAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPA----ESASFA 1186
Cdd:cd21576 101 EDSGE--APRASSGSSD-PARGSSPTLGSEPaPASGEDAVSGPESSFGAPAIPSAPAAPGAPAVSGEVPGgapgAGPAPA 177
|
170
....*....|....
gi 2245149928 1187 AVVATLEEPTSPAA 1200
Cdd:cd21576 178 AGPAPRRRPVTPAA 191
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1408-2016 |
7.42e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 45.44 E-value: 7.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1408 KEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEHDMEEINARWNTLNK---KVAQRIAQLQEALlhcGKFQDALEPLL 1484
Cdd:PRK03918 196 KEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKeleSLEGSKRKLEEKI---RELEERIEELK 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1485 SWLADTEELIanqkppsAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIaqSAELADREKITGQLESLESRWTEL 1564
Cdd:PRK03918 273 KEIEELEEKV-------KELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRL--EEEINGIEERIKELEEKEERLEEL 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1565 LSKAAARQKQLEDILVLAKQFhETAEPISDFLSVTEKKLANSEPvgtqtAKIQQQIirhkalnEEIVNRKKNVDQAIKNg 1644
Cdd:PRK03918 344 KKKLKELEKRLEELEERHELY-EEAKAKKEELERLKKRLTGLTP-----EKLEKEL-------EELEKAKEEIEEEISK- 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1645 qallkqttgeevllIQEKLDGIKTRYADItvtsSKALRTLEQA--------RQLATKFQSTY-EELTGWLREVEEELATs 1715
Cdd:PRK03918 410 --------------ITARIGELKKEIKEL----KKAIEELKKAkgkcpvcgRELTEEHRKELlEEYTAELKRIEKELKE- 470
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1716 ggqspTGEQIPQFQQRQKELKKEVMEHRLVLdTVNEVSRALLELVPWRAREGLDKLVSDANEQYKLVSDTIG-------- 1787
Cdd:PRK03918 471 -----IEEKERKLRKELRELEKVLKKESELI-KLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKlkgeiksl 544
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1788 -QRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQDQTTaqLQVQKAFSIDIIRHKDSMDELfshrseif 1866
Cdd:PRK03918 545 kKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEER--LKELEPFYNEYLELKDAEKEL-------- 614
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1867 gtcgEEQKTVLQEKTESLIQQYEAISLLNS---ERYARLERAQVLVNQfwETYEELSPWIEETRALIAqlpspaidheQL 1943
Cdd:PRK03918 615 ----EREEKELKKLEEELDKAFEELAETEKrleELRKELEELEKKYSE--EEYEELREEYLELSRELA----------GL 678
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 1944 RQQQEEMRQLRESIAEhkpHIDKLLKigpQLKELnpEEGEMVEEKYQKAENMYAQIKEEVRQ-RALALDEAVSQ 2016
Cdd:PRK03918 679 RAELEELEKRREEIKK---TLEKLKE---ELEER--EKAKKELEKLEKALERVEELREKVKKyKALLKERALSK 744
|
|
| PRK10118 |
PRK10118 |
flagellar hook length control protein FliK; |
1076-1257 |
7.53e-04 |
|
flagellar hook length control protein FliK;
Pssm-ID: 236652 [Multi-domain] Cd Length: 408 Bit Score: 44.86 E-value: 7.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1076 EEPTSPAAAVPTPEEPTSPAAavpTPEEPTSPAAAVPTPEEPASPAAAVpTPEEPASPAAAVPT-PEEPAFPAPAVPTPE 1154
Cdd:PRK10118 90 LIPVDETLPVITDEQSLSSPL---TPALKTSALAALSKNAQKDEKADDL-SDEDLASLSALFAMlPGQDNTTPVADAPST 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1155 ESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEP--ASLA 1232
Cdd:PRK10118 166 VLPAEKPTLLTKDMPSAPQDETHTLSSDEHEKGLTSAQLTTAQPDDAPGTPAQPLTPLAAEAQAKAEVISTPSPvtAAAS 245
|
170 180
....*....|....*....|....*
gi 2245149928 1233 AAVSNPEEPTSPAAAVPTLEEPTSS 1257
Cdd:PRK10118 246 PTITPHQTQPLPTAAAPVLSAPLGS 270
|
|
| PRK10819 |
PRK10819 |
transport protein TonB; Provisional |
956-1097 |
7.61e-04 |
|
transport protein TonB; Provisional
Pssm-ID: 236768 [Multi-domain] Cd Length: 246 Bit Score: 44.29 E-value: 7.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 956 AALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAavrVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPP 1035
Cdd:PRK10819 29 GLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQA---VQPPPEPVVEPEPEPEPIPEPPKEAPVVIPKPEPKPKPKPKP 105
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 1036 PEEPTSPAAAVPTPE----EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP---EEPTSPAAA 1097
Cdd:PRK10819 106 KPKPVKKVEEQPKREvkpvEPRPASPFENTAPARPTSSTATAAASKPVTSVSSGPRAlsrNQPQYPARA 174
|
|
| PHA02030 |
PHA02030 |
hypothetical protein |
1104-1174 |
7.73e-04 |
|
hypothetical protein
Pssm-ID: 222843 [Multi-domain] Cd Length: 336 Bit Score: 44.59 E-value: 7.73e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1104 PTSPAAAVPTPEEPASPAAAVPTPeePASPAAAVPT-PEEPAFPA-PAVPTPEESAsAAVAVPTPEESASPAA 1174
Cdd:PHA02030 264 SNLPAVPNVAADAGSAAAPAVPAA--AAAVAQAAPSvPQVPNVAVlPDVPQVAPVA-APAAPEVPAVPVVPAA 333
|
|
| EFh |
cd00051 |
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal ... |
3146-3197 |
7.78e-04 |
|
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to the activation or inactivation of target proteins. EF-hands tend to occur in pairs or higher copy numbers.
Pssm-ID: 238008 [Multi-domain] Cd Length: 63 Bit Score: 40.22 E-value: 7.78e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 3146 ELKE-FANFDFD----VWRKKYMRWMNH-----KKSRVMDFFRRIDKDQDGKITRQEFIDGI 3197
Cdd:cd00051 1 ELREaFRLFDKDgdgtISADELKAALKSlgeglSEEEIDEMIREVDKDGDGKIDFEEFLELM 62
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
1693-1789 |
8.09e-04 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 41.16 E-value: 8.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1693 KFQSTYEELTGWLREVEEELATSG-GQSPtgEQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPwRAREGLDKL 1771
Cdd:smart00150 2 QFLRDADELEAWLEEKEQLLASEDlGKDL--ESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGH-PDAEEIEER 78
|
90
....*....|....*...
gi 2245149928 1772 VSDANEQYKLVSDTIGQR 1789
Cdd:smart00150 79 LEELNERWEELKELAEER 96
|
|
| PRK04654 |
PRK04654 |
sec-independent translocase; Provisional |
1015-1125 |
8.22e-04 |
|
sec-independent translocase; Provisional
Pssm-ID: 135173 [Multi-domain] Cd Length: 214 Bit Score: 43.65 E-value: 8.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1015 SPAAAVPTPEE----PTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAvpTPEE 1090
Cdd:PRK04654 103 TSATPVATPLElahaDLSASAQVDAAAGAEPGAGQAHTPVPAPAPVIAQAQPIAPAPHQTLVPAPHDTIVPAPH--AAHL 180
|
90 100 110
....*....|....*....|....*....|....*.
gi 2245149928 1091 PTSPAAAVPT-PEEPTSPAAavPTPEEPASPAAAVP 1125
Cdd:PRK04654 181 PSAPATPVSVaPVDAGTSAS--PTPSEPTKIQEKQP 214
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
1225-1300 |
8.44e-04 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 45.38 E-value: 8.44e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1225 SEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAvsnleEPASPAAAV 1300
Cdd:COG5373 34 EAELAEAAEAASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEA-----EPAAAPAAA 104
|
|
| DedD |
COG3147 |
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, ... |
1091-1157 |
8.64e-04 |
|
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442381 [Multi-domain] Cd Length: 140 Bit Score: 42.45 E-value: 8.64e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEepASPAAAVPTPEEPAFPAPAVPTPEESA 1157
Cdd:COG3147 1 PAEEAAAAPAAAAAPAAPAAAAAPAPAAAAAAAAPKPA--AKPAAPKPAAAAAAAPAAKAAAPAGGG 65
|
|
| PDHac_trf_long |
TIGR01348 |
pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; This model ... |
887-1095 |
8.74e-04 |
|
pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; This model describes a subset of pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase specifically close by both phylogenetic and per cent identity (UPGMA) trees. Members of this set include two or three copies of the lipoyl-binding domain. E. coli AceF is a member of this model, while mitochondrial and some other bacterial forms belong to a separate model. [Energy metabolism, Pyruvate dehydrogenase]
Pssm-ID: 273566 [Multi-domain] Cd Length: 546 Bit Score: 45.25 E-value: 8.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 887 SIVSLEEeDVTAAAVSAPERATVPAVTVSV----PEG---------TAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSP 953
Cdd:TIGR01348 32 SLITLES-DKASMEVPSSAAGIIKEIKVKVgdtlPVGgviatlevgAGAQAQAEAKKEAAPAPTAGAPAPAAQAQAAPAA 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 954 EWAALAITVPITEEDGTPEGPVTPA-TTVHAPEEPDTAAVRVstpeEPASPAAAVPTPEEPTSPAAAVPTPEE-PTSPAA 1031
Cdd:TIGR01348 111 GQSSGVQEVTVPDIGDIEKVTVIEVlVKVGDTVSADQSLITL----ESDKASMEVPAPASGVVKSVKVKVGDSvPTGDLI 186
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 1032 AVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1095
Cdd:TIGR01348 187 LTLSVAGSTPATAPAPASAQPAAQSPAATQPEPAAAPAAAKAQAPAPQQAGTQNPAKVDHAAPA 250
|
|
| PRK13108 |
PRK13108 |
prolipoprotein diacylglyceryl transferase; Reviewed |
848-1061 |
8.96e-04 |
|
prolipoprotein diacylglyceryl transferase; Reviewed
Pssm-ID: 237284 [Multi-domain] Cd Length: 460 Bit Score: 44.97 E-value: 8.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 848 DAALPSPEEgtsiaavpapegtavvaalvpfphedilvasivsleeedVTAAAVSAPERATVPAvtvsvPEGTAAvaavs 927
Cdd:PRK13108 294 EALEREPAE---------------------------------------LAAAAVASAASAVGPV-----GPGEPN----- 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 928 speeTAPAVAAAITQEGMSAVAGFSPEwAALAITVPITEEDGTPEGPVTPAttVHAPEEPDTAAVRVSTPEEPASPAAAv 1007
Cdd:PRK13108 325 ----QPDDVAEAVKAEVAEVTDEVAAE-SVVQVADRDGESTPAVEETSEAD--IEREQPGDLAGQAPAAHQVDAEAASA- 396
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1008 pTPEEPTSPAAAVPTPEEPTSP--AAAVPPPEEPTSPAAAVPTPeEPTSPAAAVPT 1061
Cdd:PRK13108 397 -APEEPAALASEAHDETEPEVPekAAPIPDPAKPDELAVAGPGD-DPAEPDGIRRQ 450
|
|
| KLF9_13_N-like |
cd21975 |
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like ... |
1108-1266 |
8.98e-04 |
|
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like transcription factors (KLFs) belong to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the related N-terminal domains of KLF9, KLF13, KLF14, KLF16, and similar proteins.
Pssm-ID: 409240 [Multi-domain] Cd Length: 163 Bit Score: 42.76 E-value: 8.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1108 AAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAfpAPAVPTPEESASAAVAVPTPEeSASPAAAVPTPAESASFAA 1187
Cdd:cd21975 14 AGAVVHGVRPDPEGAGLAAGLDVRATREVAKGPGPPG--PAWKPDGADSPGLVTAAPHLL-AANVLAPLRGPSVEGSSLE 90
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 1188 VVATLEEPTSPAASVPTPAAMvatleefTSPAASvptSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEE 1266
Cdd:cd21975 91 SGDADMGSDSDVAPASGAAAS-------TSPESS---SDAASSPSPLSLLHPGEAGLEPERPRPRVRRGVRRRGVTPAA 159
|
|
| PRK04654 |
PRK04654 |
sec-independent translocase; Provisional |
1002-1112 |
9.01e-04 |
|
sec-independent translocase; Provisional
Pssm-ID: 135173 [Multi-domain] Cd Length: 214 Bit Score: 43.65 E-value: 9.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1002 SPAAAVPTPEE----PTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAvpTPEE 1077
Cdd:PRK04654 103 TSATPVATPLElahaDLSASAQVDAAAGAEPGAGQAHTPVPAPAPVIAQAQPIAPAPHQTLVPAPHDTIVPAPH--AAHL 180
|
90 100 110
....*....|....*....|....*....|....*.
gi 2245149928 1078 PTSPAAAVPT-PEEPTSPAAavPTPEEPTSPAAAVP 1112
Cdd:PRK04654 181 PSAPATPVSVaPVDAGTSAS--PTPSEPTKIQEKQP 214
|
|
| DedD |
COG3147 |
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, ... |
1065-1136 |
9.24e-04 |
|
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442381 [Multi-domain] Cd Length: 140 Bit Score: 42.07 E-value: 9.24e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1065 PTSPAAAVPTPEEptspAAAVPTPEEPTSPAAAVPTPEepTSPAAAvPTPEEPASPAAAVPTPEEPASPAAA 1136
Cdd:COG3147 1 PAEEAAAAPAAAA----APAAPAAAAAPAPAAAAAAAA--PKPAAK-PAAPKPAAAAAAAPAAKAAAPAGGG 65
|
|
| PRK14954 |
PRK14954 |
DNA polymerase III subunits gamma and tau; Provisional |
1023-1138 |
9.35e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184918 [Multi-domain] Cd Length: 620 Bit Score: 44.93 E-value: 9.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1023 PEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAavptPEEPTSPAAAVPTPEEPTSPAAAVPTPEE---PTSPAAAVP 1099
Cdd:PRK14954 376 NDGGVAPSPAGSPDVKKKAPEPDLPQPDRHPGPAK----PEAPGARPAELPSPASAPTPEQQPPVARSaplPPSPQASAP 451
|
90 100 110
....*....|....*....|....*....|....*....
gi 2245149928 1100 TPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP 1138
Cdd:PRK14954 452 RNVASGKPGVDLGSWQGKFMNFTRNGSRKQPVQASSSDA 490
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
3014-3139 |
9.48e-04 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 41.15 E-value: 9.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 3014 LEELLAWIQWAETTLIQRDqepIPQNIDRVKALIAEHQTFMEEMTRKQPDVDRVTKTYKR-KNIEPTHAPFIEKsrsggr 3092
Cdd:pfam00435 10 ADDLESWIEEKEALLSSED---YGKDLESVQALLKKHKALEAELAAHQDRVEALNELAEKlIDEGHYASEEIQE------ 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 2245149928 3093 kslsqptpppmpilsqseaknpRINQLSARWQQVWLLALERQRKLND 3139
Cdd:pfam00435 81 ----------------------RLEELNERWEQLLELAAERKQKLEE 105
|
|
| DUF3729 |
pfam12526 |
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ... |
1216-1303 |
9.59e-04 |
|
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.
Pssm-ID: 372164 [Multi-domain] Cd Length: 115 Bit Score: 41.60 E-value: 9.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1216 TSPAASVPTSEEPASLAAAvSNPEEPTSPAAAVPtleePTSSAAAVL--TPEELSSPAASVPTPEEPASPAAAVsnleEP 1293
Cdd:pfam12526 22 TSGFSSCFSPPESAHPDPP-PPVGDPRPPVVDTP----PPVSAVWVLppPSEPAAPEPDLVPPVTGPAGPPSPL----AP 92
|
90
....*....|
gi 2245149928 1294 ASPAAAVPTP 1303
Cdd:pfam12526 93 PAPAQKPPLP 102
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
980-1104 |
9.61e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 45.15 E-value: 9.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 980 TVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTS-PAAAVPPPEEPTSPAAAVPTPEEPTSPAAA 1058
Cdd:PRK14971 368 DASGGRGPKQHIKPVFTQPAAAPQPSAAAAASPSPSQSSAAAQPSAPQSaTQPAGTPPTVSVDPPAAVPVNPPSTAPQAV 447
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 2245149928 1059 VPTPEEPTSPAAAVPTP-EEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1104
Cdd:PRK14971 448 RPAQFKEEKKIPVSKVSsLGPSTLRPIQEKAEQATGNIKEAPTGTQK 494
|
|
| DUF3729 |
pfam12526 |
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ... |
1079-1166 |
9.78e-04 |
|
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.
Pssm-ID: 372164 [Multi-domain] Cd Length: 115 Bit Score: 41.60 E-value: 9.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1079 TSPAAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPtpeePASPAAAV--PTPEEPASPAAAVPTPEEPAFPaPAVPTPEES 1156
Cdd:pfam12526 22 TSGFSSCFSPPESAHPDPP-PPVGDPRPPVVDTP----PPVSAVWVlpPPSEPAAPEPDLVPPVTGPAGP-PSPLAPPAP 95
|
90
....*....|
gi 2245149928 1157 ASaavAVPTP 1166
Cdd:pfam12526 96 AQ---KPPLP 102
|
|
| PLN02983 |
PLN02983 |
biotin carboxyl carrier protein of acetyl-CoA carboxylase |
974-1052 |
9.86e-04 |
|
biotin carboxyl carrier protein of acetyl-CoA carboxylase
Pssm-ID: 215533 [Multi-domain] Cd Length: 274 Bit Score: 44.06 E-value: 9.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 974 PVTPATTVHAPEEPDTAAVRVSTPeePASPAAAVPTPeeptSPAAAVPTPEEPTSPAAAVPPPEeptSPAAAV----PTP 1049
Cdd:PLN02983 144 PPPPAPVVMMQPPPPHAMPPASPP--AAQPAPSAPAS----SPPPTPASPPPAKAPKSSHPPLK---SPMAGTfyrsPAP 214
|
...
gi 2245149928 1050 EEP 1052
Cdd:PLN02983 215 GEP 217
|
|
| PHA02777 |
PHA02777 |
major capsid L1 protein; Provisional |
997-1277 |
9.95e-04 |
|
major capsid L1 protein; Provisional
Pssm-ID: 165142 Cd Length: 555 Bit Score: 45.02 E-value: 9.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 997 PEEPASPAAAVPTPEEPTSPaaAVPTPEEPTSPAAAvpppEEPTSPaAAVPtPEEPTspaaavpTPEEPTSPAAAVPTPE 1076
Cdd:PHA02777 93 PIDAEAGALAEEIELLPMAP--ISGRARDPFGEGFG----EEPFDP-IGIP-PERPN-------ILHEQRFPTDAAPFDN 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1077 EPTSpAAAVPTPEEPTSPAAAVPTPEEPTSPaaavptpeepaSPAAAVPTPEEPASPAAAVPTPEEpafpapaVPTPEES 1156
Cdd:PHA02777 158 GNTD-IATIEGPHDPFGAGGDIAIIELPSVN-----------DPGPSVTARTQYNNPAFEVEIHSD-------IPSAETS 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1157 ASAAVAVPTPEESASPA--AAVPTPAESASFAAVVATLE--------EPTSPAASVPTPAamvatleeftspaasVPTSE 1226
Cdd:PHA02777 219 STDHIIVGAESGGSFVGddAEFEIPLLDAERAILDDQADtsfiahgeEEEAFLTSTPDPV---------------LPIQE 283
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 1227 EPASL--------AAAVSNPEEPTSPAAAVpTLEEPTSSAAAVLTPEELSSPAASVPTP 1277
Cdd:PHA02777 284 AIAPIrpygrqfgQVRVGDAAFLDRAAVLF-QAENPAFDADISILFEDDLADAERLDDD 341
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
1091-1184 |
1.03e-03 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 44.25 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEepafpAPAVPTPEESASAAVAVPTPEeSA 1170
Cdd:PRK10856 163 PLDTSTTTDPATTPAPAAPVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPS-----QANVDTAATPAPAAPATPDGA-AP 236
|
90
....*....|....*.
gi 2245149928 1171 SPA--AAVPTPAESAS 1184
Cdd:PRK10856 237 LPTdqAGVSTPAADPN 252
|
|
| PHA03381 |
PHA03381 |
tegument protein VP22; Provisional |
973-1123 |
1.06e-03 |
|
tegument protein VP22; Provisional
Pssm-ID: 177618 [Multi-domain] Cd Length: 290 Bit Score: 44.23 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 973 GPVTPATT--VHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPT--------PEEPTSPAAAVPPPEEP-TS 1041
Cdd:PHA03381 24 DFISPDASpaRVSFEEPADRARRGAGQARGRSQAERRFHHYDEARADYPYYTgsssederPADPRPSRRPHAQPEASgPG 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1042 PAAAVPTPEEPTSPAAAVPTP---EEPTSPAAAVPTPEEPTSPAAAVPtpeePTSPAAAVPTPEEPTSPAA-------AV 1111
Cdd:PHA03381 104 PARGARGPAGSRGRGRRAESPsprDPPNPKGASAPRGRKSACADSAAL----LDAPAPAAPKRQKTPAGLArklhfstAP 179
|
170
....*....|..
gi 2245149928 1112 PTPEEPASPAAA 1123
Cdd:PHA03381 180 TSPTAPWTPRVA 191
|
|
| Pneumo_att_G |
pfam05539 |
Pneumovirinae attachment membrane glycoprotein G; |
994-1169 |
1.07e-03 |
|
Pneumovirinae attachment membrane glycoprotein G;
Pssm-ID: 114270 [Multi-domain] Cd Length: 408 Bit Score: 44.65 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 994 VSTPEEPASPAAAVPTPEEPTSpaaaVPTPEEPTSPAAAVPPPEEPTSPAAA----VPTPEEPTSPAAAVPTPEEPTSPA 1069
Cdd:pfam05539 162 VSCCKEPKTAVTTSKTTSWPTE----VSHPTYPSQVTPQSQPATQGHQTATAnqrlSSTEPVGTQGTTTSSNPEPQTEPP 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1070 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEePTSPaaavPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPA 1149
Cdd:pfam05539 238 PSQRGPSGSPQHPPSTTSQDQSTTGDGQEHTQR-RKTP----PATSNRRSPHSTATPPPTTKRQETGRPTPRPTATTQSG 312
|
170 180
....*....|....*....|
gi 2245149928 1150 VPTPEESASAAVAVPTPEES 1169
Cdd:pfam05539 313 SSPPHSSPPGVQANPTTQNL 332
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1446-1933 |
1.12e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.76 E-value: 1.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1446 EEINARWNTLNKKVA---QRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQ---KPPSAEYKVVKAQIQEQKLLQR 1519
Cdd:COG4717 84 EEKEEEYAELQEELEeleEELEELEAELEELREELEKLEKLLQLLPLYQELEALEaelAELPERLEELEERLEELRELEE 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1520 LLDDRKATVDMLQAEGGRIAQSAELADREkitgQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVT 1599
Cdd:COG4717 164 ELEELEAELAELQEELEELLEQLSLATEE----ELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAA 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1600 EKKLANSEpvGTQTAKIQQQIIRHKALNEEIVNRKKNVDQAIKNGQALLkqtTGEEVLLIQEKLDGIKTRYADITVTSSK 1679
Cdd:COG4717 240 ALEERLKE--ARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLL---ALLFLLLAREKASLGKEAEELQALPALE 314
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1680 ALRTLEQARQLATKFQSTYEELTGWLREVeeelatsggqsptgEQIPQFQQRQKELKKevMEHRLVLDTVNEVSRALLEL 1759
Cdd:COG4717 315 ELEEEELEELLAALGLPPDLSPEELLELL--------------DRIEELQELLREAEE--LEEELQLEELEQEIAALLAE 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1760 VPWRAREGLDKLVSDANEQYKLVsdtigQRVDEIDaaiqrsQQYEQAADAELAWVAETKRKlmalgPIRLEQDQTTAQLQ 1839
Cdd:COG4717 379 AGVEDEEELRAALEQAEEYQELK-----EELEELE------EQLEELLGELEELLEALDEE-----ELEEELEELEEELE 442
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1840 VQKAfsidiiRHKDSMDELFSHRSEIFGTCGEEQKTVLQEKTESLIQQYEAIsllnSERYARLERAQVLVNQFWETYEE- 1918
Cdd:COG4717 443 ELEE------ELEELREELAELEAELEQLEEDGELAELLQELEELKAELREL----AEEWAALKLALELLEEAREEYREe 512
|
490
....*....|....*.
gi 2245149928 1919 -LSPWIEETRALIAQL 1933
Cdd:COG4717 513 rLPPVLERASEYFSRL 528
|
|
| PRK04654 |
PRK04654 |
sec-independent translocase; Provisional |
1028-1138 |
1.15e-03 |
|
sec-independent translocase; Provisional
Pssm-ID: 135173 [Multi-domain] Cd Length: 214 Bit Score: 43.26 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1028 SPAAAVPPPEE----PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAvpTPEE 1103
Cdd:PRK04654 103 TSATPVATPLElahaDLSASAQVDAAAGAEPGAGQAHTPVPAPAPVIAQAQPIAPAPHQTLVPAPHDTIVPAPH--AAHL 180
|
90 100 110
....*....|....*....|....*....|....*.
gi 2245149928 1104 PTSPAAAVPT-PEEPASPAAavPTPEEPASPAAAVP 1138
Cdd:PRK04654 181 PSAPATPVSVaPVDAGTSAS--PTPSEPTKIQEKQP 214
|
|
| PHA03291 |
PHA03291 |
envelope glycoprotein I; Provisional |
1172-1311 |
1.21e-03 |
|
envelope glycoprotein I; Provisional
Pssm-ID: 223033 [Multi-domain] Cd Length: 401 Bit Score: 44.18 E-value: 1.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1172 PAAAVPTPAESASFAAvvatlEEPTSPAasVPTPAAMVATLEEFTsPAASVPTSEEPASlaaavsnPEEPTSPAAAVPTL 1251
Cdd:PHA03291 167 PAEGTLAAPPLGEGSA-----DGSCDPA--LPLSAPRLGPADVFV-PATPRPTPRTTAS-------PETTPTPSTTTSPP 231
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1252 EEPTSSAAAVLTPEElssPAASVPTPEEPASPAAAVSNleepASPAAAVPTPEVA------------AIPAA 1311
Cdd:PHA03291 232 STTIPAPSTTIAAPQ---AGTTPEAEGTPAPPTPGGGE----APPANATPAPEASryeltvtqiiqiAIPAS 296
|
|
| ftsN |
TIGR02223 |
cell division protein FtsN; FtsN is a poorly conserved protein active in cell division in a ... |
1016-1189 |
1.21e-03 |
|
cell division protein FtsN; FtsN is a poorly conserved protein active in cell division in a number of Proteobacteria. The N-terminal 30 residue region tends to by Lys/Arg-rich, and is followed by a membrane-spanning region. This is followed by an acidic low-complexity region of variable length and a well-conserved C-terminal domain of two tandem regions matched by pfam05036 (Sporulation related repeat), found in several cell division and sporulation proteins. The role of FtsN as a suppressor for other cell division mutations is poorly understood; it may involve cell wall hydrolysis. [Cellular processes, Cell division]
Pssm-ID: 274041 [Multi-domain] Cd Length: 298 Bit Score: 43.91 E-value: 1.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1016 PAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPtSPAAAVPTPEEPTSPAAAVPTPEEP---T 1092
Cdd:TIGR02223 53 QANEPETLQPKNQTENGETAADLPPKPEERWSYIEELEAREVLINDPEEP-SNGGGVEESAQLTAEQRQLLEQMQAdmrA 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1093 SPAAAVPTPEE----PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAvpTPEESASAAVAVPTPEE 1168
Cdd:TIGR02223 132 AEKVLATAPSEqtvaVEARKQTAEKKPQKARTAEAQKTPVETEKIASKVKEAKQKQKALPK--QTAETQSNSKPIETAPK 209
|
170 180
....*....|....*....|.
gi 2245149928 1169 SASPAAAVPTPAESASFAAVV 1189
Cdd:TIGR02223 210 ADKADKTKPKPKEKAERAAAL 230
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
1125-1279 |
1.23e-03 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 43.99 E-value: 1.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1125 PTPEEPASPAAAVPTPEepafPAPAVPTPEEsasaAVAVPTPEesasPAAAVPTPAESASFAAVVATLEEPTSPAASVPT 1204
Cdd:NF040712 190 PDFGRPLRPLATVPRLA----REPADARPEE----VEPAPAAE----GAPATDSDPAEAGTPDDLASARRRRAGVEQPED 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1205 PAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPtleEPTSSAAAVLTPEELSSPA---------ASVP 1275
Cdd:NF040712 258 EPVGPGAAPAAEPDEATRDAGEPPAPGAAETPEAAEPPAPAPAAP---AAPAAPEAEEPARPEPPPApkpkrrrrrASVP 334
|
....
gi 2245149928 1276 TPEE 1279
Cdd:NF040712 335 SWDD 338
|
|
| PRK11901 |
PRK11901 |
hypothetical protein; Reviewed |
1040-1175 |
1.25e-03 |
|
hypothetical protein; Reviewed
Pssm-ID: 237015 [Multi-domain] Cd Length: 327 Bit Score: 43.90 E-value: 1.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1040 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP-------EEP----------------TSPAA 1096
Cdd:PRK11901 88 SSGNQSSPSAANNTSDGHDASGVKNTAPPQDISAPPISPTPTQAAPPQTpngqqriELPgnisdalsqqqgqvnaASQNA 167
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 1097 AVPTPEEPTSPAAaVPTPEEPASPAAAVPTPEEPASPAAAVPTPEepafPAPAVPTPEESASAAVAVPTPEESASPAAA 1175
Cdd:PRK11901 168 QGNTSTLPTAPAT-VAPSKGAKVPATAETHPTPPQKPATKKPAVN----HHKTATVAVPPATSGKPKSGAASARALSSA 241
|
|
| PRK04654 |
PRK04654 |
sec-independent translocase; Provisional |
1067-1177 |
1.32e-03 |
|
sec-independent translocase; Provisional
Pssm-ID: 135173 [Multi-domain] Cd Length: 214 Bit Score: 43.26 E-value: 1.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1067 SPAAAVPTPEE----PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAvpTPEE 1142
Cdd:PRK04654 103 TSATPVATPLElahaDLSASAQVDAAAGAEPGAGQAHTPVPAPAPVIAQAQPIAPAPHQTLVPAPHDTIVPAPH--AAHL 180
|
90 100 110
....*....|....*....|....*....|....*
gi 2245149928 1143 PAFPAPAVPTPEESASAAvAVPTPEESASPAAAVP 1177
Cdd:PRK04654 181 PSAPATPVSVAPVDAGTS-ASPTPSEPTKIQEKQP 214
|
|
| PRK12373 |
PRK12373 |
NADH-quinone oxidoreductase subunit E; |
970-1097 |
1.37e-03 |
|
NADH-quinone oxidoreductase subunit E;
Pssm-ID: 237082 [Multi-domain] Cd Length: 400 Bit Score: 44.02 E-value: 1.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 970 TPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTP 1049
Cdd:PRK12373 198 TEEAGKARYNASKALAEDIGDTVKRIDGTEVPLLAPWQGDAAPVPPSEAARPKSADAETNAALKTPATAPKAAAKNAKAP 277
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2245149928 1050 EEPTSPAAAVPTPeeptSPAAAVPTPEEPTSPAAAV-PTPEEPTSPAAA 1097
Cdd:PRK12373 278 EAQPVSGTAAAEP----APKEAAKAAAAAAKPALEDkPRPLGIARPGGA 322
|
|
| ZipA |
COG3115 |
Cell division protein ZipA, interacts with FtsZ [Cell cycle control, cell division, chromosome ... |
977-1103 |
1.41e-03 |
|
Cell division protein ZipA, interacts with FtsZ [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442349 [Multi-domain] Cd Length: 298 Bit Score: 43.91 E-value: 1.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 977 PATTVHAPEEPDTAAVRVSTPEEPA--SPAAAVPTPEEPTSPAAAVPTPEEpTSPAAAVPPPEEPTSPAAAVPTPEepts 1054
Cdd:COG3115 38 PSKRDVLLDDDGIGEVRVVAAEAPErvEPEASFDAEDEVREPDQEEVDPLL-DDEADIEAAPAEPVRWAGTAAAVE---- 112
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2245149928 1055 pAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1103
Cdd:COG3115 113 -PAPEQEAYEEAGPAGESAEQEDAPAEEPEAEAPAEEALAAELCAEPEE 160
|
|
| PRK14954 |
PRK14954 |
DNA polymerase III subunits gamma and tau; Provisional |
1021-1137 |
1.42e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184918 [Multi-domain] Cd Length: 620 Bit Score: 44.55 E-value: 1.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1021 PTPEEPTSPAAAVPPPEEPTSPAAAVP-TPEEPTSPAAAVPTPEEPTSPAAAVPTPEE---PTSPAAAVPTPEEPTSPAA 1096
Cdd:PRK14954 382 PSPAGSPDVKKKAPEPDLPQPDRHPGPaKPEAPGARPAELPSPASAPTPEQQPPVARSaplPPSPQASAPRNVASGKPGV 461
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 2245149928 1097 AVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAV 1137
Cdd:PRK14954 462 DLGSWQGKFMNFTRNGSRKQPVQASSSDAAQTGVFEGVAEL 502
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
1237-1317 |
1.42e-03 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 44.88 E-value: 1.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1237 NPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAavsnleePASPAAAvPTPEVAAIPAASVPTP 1316
Cdd:PRK12270 37 GPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPK-------PAAAAAA-AAAPAAPPAAAAAAAP 108
|
.
gi 2245149928 1317 E 1317
Cdd:PRK12270 109 A 109
|
|
| EFh_CREC_RCN3 |
cd16230 |
EF-hand, calcium binding motif, found in reticulocalbin-3 (RCN-3); RCN-3, also termed EF-hand ... |
3177-3234 |
1.46e-03 |
|
EF-hand, calcium binding motif, found in reticulocalbin-3 (RCN-3); RCN-3, also termed EF-hand calcium-binding protein RLP49, is a putative six EF-hand Ca2+-binding protein that contains five RXXR (X is any amino acid) motifs and a C-terminal ER retrieval signal His-Asp-Glu-Leu (HDEL) tetrapeptide. The RXXR motif represents the target sequence of subtilisin-like proprotein convertases (SPCs). RCN-3 is specifically bound to the paired basic amino-acid-cleaving enzyme-4 (PACE4) precursor protein and plays an important role in the biosynthesis of PACE4.
Pssm-ID: 320028 [Multi-domain] Cd Length: 268 Bit Score: 43.42 E-value: 1.46e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 3177 FRRIDKDQDGKITRQEFIDGILASKFPTTK-LEMTAVADIFDRDGDGYIDYYEFVAALH 3234
Cdd:cd16230 129 FRVADQDGDSMATREELTAFLHPEEFPHMRdIVVAETLEDLDKNKDGYVQVEEYIADLY 187
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
970-1129 |
1.46e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 44.57 E-value: 1.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 970 TPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPE------------ 1037
Cdd:PRK14948 370 NASAPANPTPAPNPSPPPAPIQPSAPKTKQAATTPSPPPAKASPPIPVPAEPTEPSPTPPANAANAPPslnleelwqqil 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1038 ---EPTS---------------PAAAV----------------------------------------PTPEEPTSPAAAV 1059
Cdd:PRK14948 450 aklELPStrmllsqqaelvsldSNRAViavspnwlgmvqsrkplleqafakvlgrsiklnlesqsgsASNTAKTPPPPQK 529
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1060 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAaavPTPEEPASPAAAVPTPEE 1129
Cdd:PRK14948 530 SPPPPAPTPPLPQPTATAPPPTPPPPPPTATQASSNAPAQIPADSSPPP---PIPEEPTPSPTKDSSPEE 596
|
|
| PRK10547 |
PRK10547 |
chemotaxis protein CheA; Provisional |
1030-1163 |
1.48e-03 |
|
chemotaxis protein CheA; Provisional
Pssm-ID: 236712 [Multi-domain] Cd Length: 670 Bit Score: 44.34 E-value: 1.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1030 AAAVPPPEEPTSPAAAVPTPEEPTSPAAA---------------VPTPEEPTSPAAAVPTPEE-PTSPAAAVPTPEEPTS 1093
Cdd:PRK10547 129 KGETPSAVTRLSVVAIQEKSEPQDESPRSqsglriilsrlkageVDLLEEELGNLGTLTDVVKgADSLEATLPGSVAEDD 208
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1094 PAAA---VPTPEE---PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAV 1163
Cdd:PRK10547 209 ITAVlcfVIEADQitfETAVAAPQEKAEETTEVVEVSPKISVPPVLKLAAEQAPAGRVEREKTARSSESTSIRVAV 284
|
|
| PRK12495 |
PRK12495 |
hypothetical protein; Provisional |
1043-1162 |
1.49e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 183558 [Multi-domain] Cd Length: 226 Bit Score: 42.93 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1043 AAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPTPEEPTSPAAAvptpeEPASPAA 1122
Cdd:PRK12495 81 GAEATAPSDAGSQASP-DDDAQPAAEAEAADQSAPPEASSTS-ATDEAATDPPATAAARDGPTPDPTA-----QPATPDE 153
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2245149928 1123 AVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVA 1162
Cdd:PRK12495 154 RRSPRQRPPVSGEPPTPSTPDAHVAGTLQAARESLVETLA 193
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
1108-1235 |
1.49e-03 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 44.19 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1108 AAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEepafPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAA 1187
Cdd:PRK06995 49 AALAPPAAAAPAAAQPPPAAAPAAVSRPAAPAAE----PAPWLVEHAKRLTAQREQLVARAAAPAAPEAQAPAAPAERAA 124
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 2245149928 1188 VVATLEEPTSPAASVPTPAAmvatleefTSPAASVPTSEEPASLAAAV 1235
Cdd:PRK06995 125 AENAARRLARAAAAAPRPRV--------PADAAAAVADAVKARIERIV 164
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1622-2241 |
1.50e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.54 E-value: 1.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1622 RHKALNEEIVNRKKNVdqaikngQALLKQTTGEEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEEL 1701
Cdd:COG1196 214 RYRELKEELKELEAEL-------LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEA 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1702 TGWLREVEEELA-TSGGQSPTGEQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLElvpwrAREGLDKLVSDANEQyk 1780
Cdd:COG1196 287 QAEEYELLAELArLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEE-----ELEEAEEELEEAEAE-- 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1781 lvsdtigqrvdEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELfs 1860
Cdd:COG1196 360 -----------LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEEL-- 426
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1861 hrseifgtcgEEQKTVLQEKTESLIQQYEAISLLNSERYARLERAQVLVNQfwetyeelspwIEETRALIAQLPSPAIDH 1940
Cdd:COG1196 427 ----------EEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE-----------LLEEAALLEAALAELLEE 485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1941 EQLRQQQEEMRQLRESIAEHKPHIDKLLKIGPQLKELNPEEGEM--VEEKYQKAenmyAQIKEEVRQRALALDEAVSQST 2018
Cdd:COG1196 486 LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLigVEAAYEAA----LEAALAAALQNIVVEDDEVAAA 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2019 QITEFHDKIEPMLETLENLSSRLRMPPLIPAEVDKIRECISDNKSATVELEklqpsfEALKRRGEELIGRSQGADKDLAA 2098
Cdd:COG1196 562 AIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREAD------ARYYVLGDTLLGRTLVAARLEAA 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2099 KEIQDKLDQMVFFW-----------EDIKARAEEREIKFLDVLELAEKFWYDMAALLTTIKDTQDIVHDLESpgidpsII 2167
Cdd:COG1196 636 LRRAVTLAGRLREVtlegeggsaggSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER------EL 709
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 2168 KQQVEAAETIKEETDGLHEELEFIRILGADLIFACGETEKPEVRKSIDEMNNAwenlnKTWKERLEKLEDAMQA 2241
Cdd:COG1196 710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL-----EELERELERLEREIEA 778
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
1122-1267 |
1.53e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 44.38 E-value: 1.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1122 AAVPTPEEPASPAAAVPTPEEPAF--PAPAVPTPeesaSAAVAVPTPEESASPAAAV-PTPAESASFAAVVATlEEPTSP 1198
Cdd:PRK14971 360 AQLTQKGDDASGGRGPKQHIKPVFtqPAAAPQPS----AAAAASPSPSQSSAAAQPSaPQSATQPAGTPPTVS-VDPPAA 434
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 1199 AASVPTPAAMVATLEEFTSPAASVPTSEEPaSLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEEL 1267
Cdd:PRK14971 435 VPVNPPSTAPQAVRPAQFKEEKKIPVSKVS-SLGPSTLRPIQEKAEQATGNIKEAPTGTQKEIFTEEDL 502
|
|
| PHA03291 |
PHA03291 |
envelope glycoprotein I; Provisional |
1083-1309 |
1.56e-03 |
|
envelope glycoprotein I; Provisional
Pssm-ID: 223033 [Multi-domain] Cd Length: 401 Bit Score: 44.18 E-value: 1.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1083 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE-EPAS---PAAAVPTPEEPASPAAAVPtpeepafPAPAVPTPeesas 1158
Cdd:PHA03291 164 AAFPAEGTLAAPPLGEGSADGSCDPALPLSAPRlGPADvfvPATPRPTPRTTASPETTPT-------PSTTTSPP----- 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1159 aavavPTPEESASPAAAVPTPAESAsfaavvatlEEPTSPAAsvPTPAAmvatleEFTSPAASVPTSEE----------- 1227
Cdd:PHA03291 232 -----STTIPAPSTTIAAPQAGTTP---------EAEGTPAP--PTPGG------GEAPPANATPAPEAsryeltvtqii 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1228 ----PASLAAAVS-----------------NPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAA 1286
Cdd:PHA03291 290 qiaiPASIIACVFlgscacclhrrcrrrrrRPARIYRPPSPVAPSISAVNEAALARLGDELKRHPPESPRRSKRRSSQTM 369
|
250 260
....*....|....*....|...
gi 2245149928 1287 VSNLEEPASPAAAVPTPEVAAIP 1309
Cdd:PHA03291 370 VPSLTAISEESEAPAVVELSRSP 392
|
|
| PRK10905 |
PRK10905 |
cell division protein DamX; Validated |
1144-1310 |
1.56e-03 |
|
cell division protein DamX; Validated
Pssm-ID: 236792 [Multi-domain] Cd Length: 328 Bit Score: 43.77 E-value: 1.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1144 AFPAPAVPTPEESASAAVAVPTPEESASPA-AAVPTP-AESASFAAVVATLEEPTSPAASVPTPAAMVATLE-----EFT 1216
Cdd:PRK10905 19 ALKAPSTSSSDQTASGEKSIDLAGNATDQAnGVQPAPgTTSAEQTAGNTQQDVSLPPISSTPTQGQTPVATDgqqrvEVQ 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1217 SPAASVPTS-EEPASLAAAVSNPEEPTSPAAAVP---------TLEEPTSSAAAVLTPE------ELSSPAASVPTPEEP 1280
Cdd:PRK10905 99 GDLNNALTQpQNQQQLNNVAVNSTLPTEPATVAPvrngnasrqTAKTQTAERPATTRPArkqaviEPKKPQATAKTEPKP 178
|
170 180 190
....*....|....*....|....*....|
gi 2245149928 1281 AspaAAVSNLEEPASPAAAVPTPEVAAIPA 1310
Cdd:PRK10905 179 V---AQTPKRTEPAAPVASTKAPAATSTPA 205
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
1146-1255 |
1.63e-03 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 44.50 E-value: 1.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1146 PAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAEsasfaavvatleEPTSPAASVPTPAAMVAtleeftsPAASVPTS 1225
Cdd:PRK12270 39 GSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAP------------PAAAAPAAPPKPAAAAA-------AAAAPAAP 99
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2245149928 1226 EEPASLAAAVSNPEEPTS-----PAAAVPT-----LEEPT 1255
Cdd:PRK12270 100 PAAAAAAAPAAAAVEDEVtplrgAAAAVAKnmdasLEVPT 139
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1679-2573 |
1.65e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.29 E-value: 1.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1679 KALRTLEQARQLATKFQSTYEELTGWLREVEEELATSggqsptgeqipqfqQRQKELKKEVMEHRlvldtVNEVSRALLE 1758
Cdd:TIGR02169 174 KALEELEEVEENIERLDLIIDEKRQQLERLRREREKA--------------ERYQALLKEKREYE-----GYELLKEKEA 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1759 LVpwRAREGLDKLVSDANEQYKLVSDTIGQRVDEIDAAIQRsqqyeqaadaelawVAETKRKLMALGpirlEQDQTTAQL 1838
Cdd:TIGR02169 235 LE--RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQL--------------LEELNKKIKDLG----EEEQLRVKE 294
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1839 QVQKaFSIDIIRHKDSMDELfshrseifgtcgEEQKTVLQEKTESLIQQYEAISLLNSERYARLERAQVLVNQFWETYEE 1918
Cdd:TIGR02169 295 KIGE-LEAEIASLERSIAEK------------ERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAE 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1919 LSpwiEETRALIAQLPSPAIDHEQLRQQ----QEEMRQLRESIAEHKPHIDKLLKIGPQLKelnpEEGEMVEEKYQKAEN 1994
Cdd:TIGR02169 362 LK---EELEDLRAELEEVDKEFAETRDElkdyREKLEKLKREINELKRELDRLQEELQRLS----EELADLNAAIAGIEA 434
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1995 MYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPML----ETLENLSSRLRMPPL----IPAEVDKIRECISDNKSATV 2066
Cdd:TIGR02169 435 KINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELydlkEEYDRVEKELSKLQRelaeAEAQARASEERVRGGRAVEE 514
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2067 ELEKLQP----SFEALKRRGEELI--------GRSQG---ADKDLAAKEIQ----DKLDQMVF--------FWEDIKARA 2119
Cdd:TIGR02169 515 VLKASIQgvhgTVAQLGSVGERYAtaievaagNRLNNvvvEDDAVAKEAIEllkrRKAGRATFlplnkmrdERRDLSILS 594
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2120 EEREIKF-LDVLELAEKFwydMAALLTTIKDTQdIVHDLESpGIDPSIIKQQVEAAETIKEE----TDGlheeleFIRIL 2194
Cdd:TIGR02169 595 EDGVIGFaVDLVEFDPKY---EPAFKYVFGDTL-VVEDIEA-ARRLMGKYRMVTLEGELFEKsgamTGG------SRAPR 663
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2195 GADLIFACGETEKPEVRKSIDEMnnawENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLctmppvGTDLN 2274
Cdd:TIGR02169 664 GGILFSRSEPAELQRLRERLEGL----KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQL------EQEEE 733
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2275 TVKDQLNEmkefkVEVYQQQIEMEKLNHQGELmlkkatDETDRDIirEPLTELKHlweNLGEKIAhrqhKLEgALLALGQ 2354
Cdd:TIGR02169 734 KLKERLEE-----LEEDLSSLEQEIENVKSEL------KELEARI--EELEEDLH---KLEEALN----DLE-ARLSHSR 792
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2355 FQHALEELmswlthtEELLDAQRPISGDPKVIEVELAKHHVLKNdvLAHQATVETVNKagNELLEssagDDASSLRSRLE 2434
Cdd:TIGR02169 793 IPEIQAEL-------SKLEEEVSRIEARLREIEQKLNRLTLEKE--YLEKEIQELQEQ--RIDLK----EQIKSIEKEIE 857
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2435 AMNqcweSVLQKTEEREQQLQSTLQQAQGFHSEIEDfllELTRMESQLSASKPTGGLPETAREQLDTHMelySQLKAKEE 2514
Cdd:TIGR02169 858 NLN----GKKEELEEELEELEAALRDLESRLGDLKK---ERDELEAQLRELERKIEELEAQIEKKRKRL---SELKAKLE 927
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 2515 TYNQLLDkgrlmllSRDDSGSGSKTEQSVALLEQKWHVVSSKMEERKSKLEEALNLATE 2573
Cdd:TIGR02169 928 ALEEELS-------EIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQ 979
|
|
| PRK05704 |
PRK05704 |
2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase; |
1093-1184 |
1.65e-03 |
|
2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase;
Pssm-ID: 235571 [Multi-domain] Cd Length: 407 Bit Score: 44.05 E-value: 1.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1093 SPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAvPTPEEPAFPAPAVP--------TPEESASAAVAVP 1164
Cdd:PRK05704 77 DEGAAAGAAAAAAAAAAAAAAAPAQAQAAAAAEQSNDALSPAAR-KLAAENGLDASAVKgtgkggrvTKEDVLAALAAAA 155
|
90 100
....*....|....*....|
gi 2245149928 1165 TPEESASPAAAVPTPAESAS 1184
Cdd:PRK05704 156 AAPAAPAAAAPAAAPAPLGA 175
|
|
| DedD |
COG3147 |
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, ... |
1026-1089 |
1.70e-03 |
|
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442381 [Multi-domain] Cd Length: 140 Bit Score: 41.30 E-value: 1.70e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 1026 PTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEptSPAAAVPTPEEPTSPAAAVPTPE 1089
Cdd:COG3147 1 PAEEAAAAPAAAAAPAAPAAAAAPAPAAAAAAAAPKPAA--KPAAPKPAAAAAAAPAAKAAAPA 62
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1897-2349 |
1.74e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 44.28 E-value: 1.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1897 ERYARLERAQV-LVNQFWETYEELSPWIEETRALIAQLPSPAIDHEQLRQQQEEMRQLRESIAEHKPHIDKLLKIGPQLK 1975
Cdd:PRK03918 293 EEYIKLSEFYEeYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKE 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1976 ELN-------PEEGEMVEEKYQKAENMyaqiKEEVRQRALALDEavsqstQITEFHDKIEPMLETLENLSSRLRMPPLIP 2048
Cdd:PRK03918 373 ELErlkkrltGLTPEKLEKELEELEKA----KEEIEEEISKITA------RIGELKKEIKELKKAIEELKKAKGKCPVCG 442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2049 AEVDK------IRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQM-----VFFWEDIKA 2117
Cdd:PRK03918 443 RELTEehrkelLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELeeklkKYNLEELEK 522
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2118 RAEEREikfldvlELAEKfwydmaaLLTTIKDTQDIVHDLESpgidpsiIKQQVEAAETIKEETDGLHEEL-EFIRILGa 2196
Cdd:PRK03918 523 KAEEYE-------KLKEK-------LIKLKGEIKSLKKELEK-------LEELKKKLAELEKKLDELEEELaELLKELE- 580
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2197 DLIFACGEtekpEVRKSIDEMNNAWENLN--KTWKERLEKLEDAMQAAvqyQDTLQAMFDWLDNTviklctmppvGTDLN 2274
Cdd:PRK03918 581 ELGFESVE----ELEERLKELEPFYNEYLelKDAEKELEREEKELKKL---EEELDKAFEELAET----------EKRLE 643
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 2275 TVKDQLNEM-KEFKVEVYqQQIEMEKLNHQGELMLKKATDETDRDIIREPLTELKHLWENLGE--KIAHRQHKLEGAL 2349
Cdd:PRK03918 644 ELRKELEELeKKYSEEEY-EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEreKAKKELEKLEKAL 720
|
|
| KLF9_13_N-like |
cd21975 |
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like ... |
1156-1316 |
1.82e-03 |
|
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like transcription factors (KLFs) belong to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the related N-terminal domains of KLF9, KLF13, KLF14, KLF16, and similar proteins.
Pssm-ID: 409240 [Multi-domain] Cd Length: 163 Bit Score: 41.98 E-value: 1.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1156 SASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAV 1235
Cdd:cd21975 13 SAGAVVHGVRPDPEGAGLAAGLDVRATREVAKGPGPPGPAWKPDGADSPGLVTAAPHLLAANVLAPLRGPSVEGSSLESG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1236 SNPEEPTSPAAavptleePTSSAAAVLTPEELSSPAAsvptpeePASPAAAVSnlEEPASPAAAVPTPEVAAIPAASVPT 1315
Cdd:cd21975 93 DADMGSDSDVA-------PASGAAASTSPESSSDAAS-------SPSPLSLLH--PGEAGLEPERPRPRVRRGVRRRGVT 156
|
.
gi 2245149928 1316 P 1316
Cdd:cd21975 157 P 157
|
|
| EF-hand_1 |
pfam00036 |
EF hand; The EF-hands can be divided into two classes: signalling proteins and buffering ... |
3172-3197 |
1.93e-03 |
|
EF hand; The EF-hands can be divided into two classes: signalling proteins and buffering/transport proteins. The first group is the largest and includes the most well-known members of the family such as calmodulin, troponin C and S100B. These proteins typically undergo a calcium-dependent conformational change which opens a target binding site. The latter group is represented by calbindin D9k and do not undergo calcium dependent conformational changes.
Pssm-ID: 425435 [Multi-domain] Cd Length: 29 Bit Score: 38.15 E-value: 1.93e-03
|
| Hamartin |
pfam04388 |
Hamartin protein; This family includes the hamartin protein which is thought to function as a ... |
960-1135 |
1.95e-03 |
|
Hamartin protein; This family includes the hamartin protein which is thought to function as a tumour suppressor. The hamartin protein interacts with the tuberin protein pfam03542. Tuberous sclerosis complex (TSC) is an autosomal dominant disorder and is characterized by the presence of hamartomas in many organs, such as brain, skin, heart, lung, and kidney. It is caused by mutation either TSC1 or TSC2 tumour suppressor gene. TSC1 encodes a protein, hamartin, containing two coiled-coil regions, which have been shown to mediate binding to tuberin. The TSC2 gene codes for tuberin pfam03542. These two proteins function within the same pathway(s) regulating cell cycle, cell growth, adhesion, and vesicular trafficking.
Pssm-ID: 461287 [Multi-domain] Cd Length: 730 Bit Score: 43.89 E-value: 1.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 960 ITVPITE---EDGTPEGPVTPATTVHapeePDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAavptpeepTSPAAAVPPP 1036
Cdd:pfam04388 256 FSLDPKEascEEGYSSSAADPTASPY----TDQQSSYGSSTSTPSSTPRLQLSSSSGTSPPY--------LSPPSIRLKT 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1037 EEPT--SPAA--AVPTPeePTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEepTSPAAAVPTPEEPTS-----P 1107
Cdd:pfam04388 324 DSFPlwSPSSvcGMTTP--PTSPGMVPTTPSELSPSSSHLSSRGSSPPEAAGEATPE--TTPAKDSPYLKQPPPlsdshV 399
|
170 180
....*....|....*....|....*...
gi 2245149928 1108 AAAVPTPEEPASPAAAVPTPEEPASPAA 1135
Cdd:pfam04388 400 HRALPASSQPSSPPRKDGRSQSSFPPLS 427
|
|
| PRK11901 |
PRK11901 |
hypothetical protein; Reviewed |
927-1074 |
1.95e-03 |
|
hypothetical protein; Reviewed
Pssm-ID: 237015 [Multi-domain] Cd Length: 327 Bit Score: 43.52 E-value: 1.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 927 SSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPiteedgtpegPVTPATTVHAPEEPDTAAVRVSTPEE------- 999
Cdd:PRK11901 86 SLSSGNQSSPSAANNTSDGHDASGVKNTAPPQDISAP----------PISPTPTQAAPPQTPNGQQRIELPGNisdalsq 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1000 ------PASPAAAVPTPEEPTSPAAaVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVpTPEEPTSPAAAVP 1073
Cdd:PRK11901 156 qqgqvnAASQNAQGNTSTLPTAPAT-VAPSKGAKVPATAETHPTPPQKPATKKPAVNHHKTATVAV-PPATSGKPKSGAA 233
|
.
gi 2245149928 1074 T 1074
Cdd:PRK11901 234 S 234
|
|
| SAV_2336_NTERM |
NF041121 |
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ... |
1119-1213 |
1.99e-03 |
|
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.
Pssm-ID: 469044 [Multi-domain] Cd Length: 473 Bit Score: 43.84 E-value: 1.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1119 SPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLeeptsp 1198
Cdd:NF041121 16 GRAAAPPSPEGPAPTAASQPATPPPPAAPPSPPGDPPEPPAPEPAPLPAPYPGSLAPPPPPPPGPAGAAPGAAL------ 89
|
90
....*....|....*
gi 2245149928 1199 AASVPTPAAMVATLE 1213
Cdd:NF041121 90 PVRVPAPPALPNPLE 104
|
|
| DUF6264 |
pfam19779 |
Family of unknown function (DUF6264); This family of putative integral membrane proteins is ... |
1010-1072 |
2.05e-03 |
|
Family of unknown function (DUF6264); This family of putative integral membrane proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 179 and 218 amino acids in length.
Pssm-ID: 466182 Cd Length: 182 Bit Score: 41.87 E-value: 2.05e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1010 PEEPTSPAAAVPTPEEPTSPAAAvPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1072
Cdd:pfam19779 9 PPGWQRAPIGDPAAAAAAAPPAA-PAPAAPAPPAAPAAPPAAPPPPGAPAPGAPAAARRARRW 70
|
|
| PRK11633 |
PRK11633 |
cell division protein DedD; Provisional |
1098-1206 |
2.07e-03 |
|
cell division protein DedD; Provisional
Pssm-ID: 236940 [Multi-domain] Cd Length: 226 Bit Score: 42.68 E-value: 2.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1098 VPTP---EEPTS-PAAAVPTPEEPASPAAavptpEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESaspa 1173
Cdd:PRK11633 44 VPKPgdrDEPDMmPAATQALPTQPPEGAA-----EAVRAGDAAAPSLDPATVAPPNTPVEPEPAPVEPPKPKPVEK---- 114
|
90 100 110
....*....|....*....|....*....|...
gi 2245149928 1174 aavPTPAESASFAAVVATLEEPTSPAASVPTPA 1206
Cdd:PRK11633 115 ---PKPKPKPQQKVEAPPAPKPEPKPVVEEKAA 144
|
|
| PRK12495 |
PRK12495 |
hypothetical protein; Provisional |
1004-1142 |
2.30e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 183558 [Multi-domain] Cd Length: 226 Bit Score: 42.55 E-value: 2.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1004 AAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPPPEEPTSPAaavptpeepTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1083
Cdd:PRK12495 81 GAEATAPSDAGSQASP-DDDAQPAAEAEAADQSAPPEASS---------TSATDEAATDPPATAAARDGPTPDPTAQPAT 150
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 1084 avPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEE 1142
Cdd:PRK12495 151 --PDERRSPRQRPPVSGEPPTPSTPDAHVAGTLQAARESLVETLARFARRAAATDDPRR 207
|
|
| PHA03325 |
PHA03325 |
nuclear-egress-membrane-like protein; Provisional |
906-1068 |
2.31e-03 |
|
nuclear-egress-membrane-like protein; Provisional
Pssm-ID: 223044 Cd Length: 418 Bit Score: 43.33 E-value: 2.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 906 RATVPAVTVSVPEGTAAVAAVSSpeeTAPAVAAAITQEGMSAVAGFSPEwaalaiTVPITEEDGTPEGPVTPATTVH--A 983
Cdd:PHA03325 256 QLTSSAFMLNSSLPTSAPKRRSR---RAGAMRAAAGETADLADDDGSEH------SDPEPLPASLPPPPVRRPRVKHpeA 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 984 PEEPDTAAvRVSTPEEPASPAAAVPTPEEP---------TSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPtPEEPTS 1054
Cdd:PHA03325 327 GKEEPDGA-RNAEAKEPAQPATSTSSKGSSsaqnkdsgsTGPGSSLAAASSFLEDDDFGSPPLDLTTSLRHMP-SPSVTS 404
|
170
....*....|....
gi 2245149928 1055 PAAAVPTPEEPTSP 1068
Cdd:PHA03325 405 APEPPSIPLTYLSD 418
|
|
| EntF |
COG1020 |
EntF, seryl-AMP synthase component of non-ribosomal peptide synthetase [Secondary metabolites ... |
870-1274 |
2.33e-03 |
|
EntF, seryl-AMP synthase component of non-ribosomal peptide synthetase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 440643 [Multi-domain] Cd Length: 1329 Bit Score: 44.08 E-value: 2.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 870 AVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPE---------GTAAVAAVSSPEETAPAVAAAI 940
Cdd:COG1020 901 AVVVAREDAPGDKRLVAYVVPEAGAAAAAALLRLALALLLPPYMVPAAVvlllplpltGNGKLDRLALPAPAAAAAAAAA 980
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 941 TQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHApeepdTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAV 1020
Cdd:COG1020 981 APPAEEEEEEAALALLLLLVVVVGDDDFFFFGGGLGLLLLLAL-----ARAARLLLLLLLLLLLFLAAAAAAAAAAAAAA 1055
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1021 PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1100
Cdd:COG1020 1056 AAAAAAPLAAAAAPLPLPPLLLSLLALLLALLLLLALLALLALLLLLLLLLLLLALLLLLALLLALLAALRARRAVRQEG 1135
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1101 PEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPA 1180
Cdd:COG1020 1136 PRLRLLVALAAALALAALLALLLAAAAAAAELLAAAALLLLLALLLLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 1215
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1181 ESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAA 1260
Cdd:COG1020 1216 LLLLLLLLLAAAAAALLALALLLALLALAALLALAALAALAAALLALALALLALALLLLALALLLPALARARAARTARAL 1295
|
410
....*....|....
gi 2245149928 1261 VLTPEELSSPAASV 1274
Cdd:COG1020 1296 ALLLLLALLLLLAL 1309
|
|
| DedD |
COG3147 |
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, ... |
1000-1063 |
2.33e-03 |
|
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442381 [Multi-domain] Cd Length: 140 Bit Score: 40.91 E-value: 2.33e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 1000 PASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEptSPAAAVPTPEEPTSPAAAVPTPE 1063
Cdd:COG3147 1 PAEEAAAAPAAAAAPAAPAAAAAPAPAAAAAAAAPKPAA--KPAAPKPAAAAAAAPAAKAAAPA 62
|
|
| DedD |
COG3147 |
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, ... |
1047-1118 |
2.36e-03 |
|
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442381 [Multi-domain] Cd Length: 140 Bit Score: 40.91 E-value: 2.36e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1047 PTPEEPTSPAAAVpTPEEPtsPAAAVPTPEEPTSPAAAVPTPeeptSPAAAVPTPEEPTSPAAAVPTPEEPA 1118
Cdd:COG3147 1 PAEEAAAAPAAAA-APAAP--AAAAAPAPAAAAAAAAPKPAA----KPAAPKPAAAAAAAPAAKAAAPAGGG 65
|
|
| KLF14_N |
cd21576 |
N-terminal domain of Kruppel-like factor 14; Kruppel-like factor 14 (KLF14; also known as ... |
1062-1220 |
2.36e-03 |
|
N-terminal domain of Kruppel-like factor 14; Kruppel-like factor 14 (KLF14; also known as Krueppel-like factor 14 or basic transcription element-binding protein 5/BTEB5) is a protein that in humans is encoded by the KLF14 gene. KLF14 regulates the transcription of various genes, including TGFbetaRII (the type II receptor for TGFbeta). KLF14 is expressed in many tissues, lacks introns, and is subject to parent-specific expression. It also appears to be a master regulator of gene expression in adipose tissue. KLF14 is associated with coronary artery disease, hypercholesterolemia, and type 2 diabetes. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. KLF14 belongs to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the N-terminal domain of KLF14.
Pssm-ID: 409238 [Multi-domain] Cd Length: 195 Bit Score: 42.11 E-value: 2.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1062 PEEPTSPAAAVPTPEEPTSPAAAVPTPEePTSPAAAVPTPEEPT-SPAAAVPTPEEPASPAAA----------VPTPEEp 1130
Cdd:cd21576 28 APDPEGAGGAAGSEVGAAPPESALPGPG-PPGPAWVPPLLQVPApSPGAGGAAPHLLAASVLAdlrggagegsREDSGE- 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1131 aSPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASpAAAVPTPAESAsfAAVVATLEEPTSPAASVPTPAAMVA 1210
Cdd:cd21576 106 -APRASSGSSDPARGSSPTLGSEPAPASGEDAVSGPESSFG-APAIPSAPAAP--GAPAVSGEVPGGAPGAGPAPAAGPA 181
|
170
....*....|
gi 2245149928 1211 TLEEFTSPAA 1220
Cdd:cd21576 182 PRRRPVTPAA 191
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
1118-1179 |
2.36e-03 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 43.52 E-value: 2.36e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1118 ASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTP 1179
Cdd:PTZ00144 120 TGGAPPAAAPAAAAAAKAEKTTPEKPKAAAPTPEPPAASKPTPPAAAKPPEPAPAAKPPPTP 181
|
|
| PRK12373 |
PRK12373 |
NADH-quinone oxidoreductase subunit E; |
999-1136 |
2.48e-03 |
|
NADH-quinone oxidoreductase subunit E;
Pssm-ID: 237082 [Multi-domain] Cd Length: 400 Bit Score: 43.25 E-value: 2.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 999 EPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAA-VPTPEEPTSPAAAVPTPEEpTSPAAAVPTPeE 1077
Cdd:PRK12373 189 EPAGGLTSLTEEAGKARYNASKALAEDIGDTVKRIDGTEVPLLAPWQgDAAPVPPSEAARPKSADAE-TNAALKTPAT-A 266
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1078 PTSPAAAVPTPEEPTSPAAAVPTPeeptSPAAAVPTPEEPASPAAAV-PTPEEPASPAAA 1136
Cdd:PRK12373 267 PKAAAKNAKAPEAQPVSGTAAAEP----APKEAAKAAAAAAKPALEDkPRPLGIARPGGA 322
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1216-1365 |
2.50e-03 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 43.75 E-value: 2.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1216 TSPAASVPTSEEPASLAAAVSNPEEPTSPAAavPTLEEPTSSAAAVLTPEELSSPAASVP-TPEEPASPAAAVSNLEEPA 1294
Cdd:pfam05109 430 TSPTLNTTGFAAPNTTTGLPSSTHVPTNLTA--PASTGPTVSTADVTSPTPAGTTSGASPvTPSPSPRDNGTESKAPDMT 507
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1295 SPAAAVPTP---EVAAIPAASVPTPEVPAIPAAAVppmEEVSPIGVPFLGVSAHTDSV--PISEEGTPVLEEASST 1365
Cdd:pfam05109 508 SPTSAVTTPtpnATSPTPAVTTPTPNATSPTLGKT---SPTSAVTTPTPNATSPTPAVttPTPNATIPTLGKTSPT 580
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
810-1023 |
2.51e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 43.71 E-value: 2.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 810 PEKQVTKAGNTEPVLEEWIPVLQRPSRT-AAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAAlVPFPHEDILVASI 888
Cdd:PRK12323 391 APAAAAPAPAAPPAAPAAAPAAAAAARAvAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAA-APAAAARPAAAGP 469
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 889 VSLEEEDVTAAAVSAPERATVPAVTVSVP-EGTAAVAAVSSPEETAPAVAAaitqegmsavagfspeWAALAITVPITEE 967
Cdd:PRK12323 470 RPVAAAAAAAPARAAPAAAPAPADDDPPPwEELPPEFASPAPAQPDAAPAG----------------WVAESIPDPATAD 533
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 968 DGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTP 1023
Cdd:PRK12323 534 PDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPALAARLP 589
|
|
| CT47 |
pfam15623 |
Cancer/testis gene family 47; CT47 is a family of proteins found in eukaryotes. Proteins in ... |
1088-1181 |
2.56e-03 |
|
Cancer/testis gene family 47; CT47 is a family of proteins found in eukaryotes. Proteins in this family are typically between 262 and 291 amino acids in length. There is a conserved HIL sequence motif. The function of this family is not known.
Pssm-ID: 464779 [Multi-domain] Cd Length: 281 Bit Score: 43.00 E-value: 2.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1088 PEEPTSPAAAVPTPEEPTSPAAAVpTPEEPASPAAAVPTPEEPASPAAAvptpEEPAFPAPAVPTPEESASAAVAVPTPE 1167
Cdd:pfam15623 170 LPRLGPVGAAAPEGEGLGLPQEAA-SVEEPAVPADLAEMAREPAEEAAE----EEPAEEAAEEPAAEEPAAEAAEEPAAE 244
|
90
....*....|....
gi 2245149928 1168 ESASPAAAVPTPAE 1181
Cdd:pfam15623 245 EAEAPEEVTKSQPE 258
|
|
| DedD |
COG3147 |
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, ... |
1052-1123 |
2.57e-03 |
|
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442381 [Multi-domain] Cd Length: 140 Bit Score: 40.91 E-value: 2.57e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1052 PTSPAAAVPTPEEptspAAAVPTPEEPTSPAAAVPTPEepTSPAAAvPTPEEPTSPAAAVPTPEEPASPAAA 1123
Cdd:COG3147 1 PAEEAAAAPAAAA----APAAPAAAAAPAPAAAAAAAA--PKPAAK-PAAPKPAAAAAAAPAAKAAAPAGGG 65
|
|
| PRK11901 |
PRK11901 |
hypothetical protein; Reviewed |
1053-1184 |
2.60e-03 |
|
hypothetical protein; Reviewed
Pssm-ID: 237015 [Multi-domain] Cd Length: 327 Bit Score: 43.13 E-value: 2.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1053 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT---------SPA---------AAVPTP 1114
Cdd:PRK11901 88 SSGNQSSPSAANNTSDGHDASGVKNTAPPQDISAPPISPTPTQAAPPQTPNGQqrielpgniSDAlsqqqgqvnAASQNA 167
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 1115 EEPAS---PAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESAS 1184
Cdd:PRK11901 168 QGNTStlpTAPATVAPSKGAKVPATAETHPTPPQKPATKKPAVNHHKTATVAVPPATSGKPKSGAASARALSS 240
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
2459-2566 |
2.63e-03 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 39.99 E-value: 2.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2459 QQAQGFHSEIEDFLLELTRMESQLSaSKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLlsrDDSGSGSK 2538
Cdd:pfam00435 1 LLLQQFFRDADDLESWIEEKEALLS-SEDYGKDLESVQALLKKHKALEAELAAHQDRVEALNELAEKLI---DEGHYASE 76
|
90 100
....*....|....*....|....*....
gi 2245149928 2539 -TEQSVALLEQKWHVVSSKMEERKSKLEE 2566
Cdd:pfam00435 77 eIQERLEELNERWEQLLELAAERKQKLEE 105
|
|
| DUF4045 |
pfam13254 |
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. ... |
1080-1334 |
2.67e-03 |
|
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. This domain family is found in bacteria and eukaryotes, and is typically between 384 and 430 amino acids in length.
Pssm-ID: 433066 [Multi-domain] Cd Length: 415 Bit Score: 43.23 E-value: 2.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1080 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT--PEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPA----PAVPTP 1153
Cdd:pfam13254 41 SFASNRGSVAGPSGSLSPGLSPTKLSREGSPESTsrPSSSHSEATIVRHSKDDERPSTPDEGFVKPALPRhsrsSSALSN 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1154 EESASAAVAVPTPEESASPAAAV----PTPA---ESAsfaavvatLEEPTSP-AASVPTPAAMVATLEEFT--------- 1216
Cdd:pfam13254 121 TGSEEDSPSLPTSPPSPSKTMDPkrwsPTKSswlESA--------LNRPESPkPKAQPSQPAQPAWMKELNkirqsrasv 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1217 ------SPAASVPTSEE-PASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTP-----------E 1278
Cdd:pfam13254 193 dlgrpnSFKEVTPVGLMrSPAPGGHSKSPSVSGISADSSPTKEEPSEEADTLSTDKEQSPAPTSASEPppktkelpkdsE 272
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 1279 EPASPAAAVSnLEEPASPAAAVPTPEVAA---IPAASVPTPEVPAIPAAAVPPMEEVSP 1334
Cdd:pfam13254 273 EPAAPSKSAE-ASTEKKEPDTESSPETSSeksAPSLLSPVSKASIDKPLSSPDRDPLSP 330
|
|
| Rib_recp_KP_reg |
pfam05104 |
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards ... |
997-1092 |
2.71e-03 |
|
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards the C-terminus of the transmembrane domain. The function is unclear.
Pssm-ID: 461548 [Multi-domain] Cd Length: 140 Bit Score: 40.88 E-value: 2.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 997 PEEPASPAAAVPTPEEPTSPAAAVPTPEeptsPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTpEEPTSPAAAVPTPe 1076
Cdd:pfam05104 51 PESEQADESEEEPREFKTPDEAPSAALE----PEPVPTPVPAPVEPEPAPPSESPAPSPKEKKKK-EKKSAKVEPAETP- 124
|
90
....*....|....*.
gi 2245149928 1077 EPTSPAAAVPTPEEPT 1092
Cdd:pfam05104 125 EAVQPKPALEKEEPPA 140
|
|
| PRK10672 |
PRK10672 |
endolytic peptidoglycan transglycosylase RlpA; |
968-1097 |
2.77e-03 |
|
endolytic peptidoglycan transglycosylase RlpA;
Pssm-ID: 236733 [Multi-domain] Cd Length: 361 Bit Score: 43.13 E-value: 2.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 968 DGTPEGPVTPATTVhapeepdtaavrvstpeepASPAAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPPPEEPTSPAAAVP 1047
Cdd:PRK10672 174 DGSLSGPGTAGTTV-------------------AKQSYALPARPDLSGGMGT-PSVQPAPAPQGDVLPVSNSTLKSEDPT 233
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1048 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1097
Cdd:PRK10672 234 GAPVTSSGFLGAPTTLAPGVLEGSEPTPTAPSSAPATAPAAAAPQAAATS 283
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
1017-1190 |
2.84e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 43.41 E-value: 2.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1017 AAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTP----EEPTSPAAAVPTPEEPTSPAAAVPTPE--- 1089
Cdd:PRK14948 361 PSAFISEIANASAPANPTPAPNPSPPPAPIQPSAPKTKQAATTPSPppakASPPIPVPAEPTEPSPTPPANAANAPPsln 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1090 ------------EPTS---------------PAAAV----------------------------------PTPEEPTSPA 1108
Cdd:PRK14948 441 leelwqqilaklELPStrmllsqqaelvsldSNRAViavspnwlgmvqsrkplleqafakvlgrsiklnlESQSGSASNT 520
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1109 AAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAvPTPAESASFAAV 1188
Cdd:PRK14948 521 AKTPPPPQKSPPPPAPTPPLPQPTATAPPPTPPPPPPTATQASSNAPAQIPADSSPPPPIPEEPTPS-PTKDSSPEEIDK 599
|
..
gi 2245149928 1189 VA 1190
Cdd:PRK14948 600 AA 601
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
1086-1280 |
2.88e-03 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 43.28 E-value: 2.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1086 PTPEEPTSPAAAVPTPEEPTSPA------AAVPTPEEPASPAAAVPTPEEPASPAAA---VPTPEEPAFPAPAVPTPEES 1156
Cdd:PRK14086 90 PSAGEPAPPPPHARRTSEPELPRpgrrpyEGYGGPRADDRPPGLPRQDQLPTARPAYpayQQRPEPGAWPRAADDYGWQQ 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1157 ASAavAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPaamvatleEFTSPAASVPTSEEPASLAAAVs 1236
Cdd:PRK14086 170 QRL--GFPPRAPYASPASYAPEQERDREPYDAGRPEYDQRRRDYDHPRP--------DWDRPRRDRTDRPEPPPGAGHV- 238
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2245149928 1237 nPEEPTSPAAAVPTLEEPTSSAAavltPEELSSPAASVPTPEEP 1280
Cdd:PRK14086 239 -HRGGPGPPERDDAPVVPIRPSA----PGPLAAQPAPAPGPGEP 277
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
971-1091 |
2.95e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 43.23 E-value: 2.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 971 PEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEepTSPAAAVPTPE 1050
Cdd:PRK14971 375 PKQHIKPVFTQPAAAPQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVPVNPPS--TAPQAVRPAQF 452
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 2245149928 1051 EPTSPAAAVPTP-EEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1091
Cdd:PRK14971 453 KEEKKIPVSKVSsLGPSTLRPIQEKAEQATGNIKEAPTGTQK 494
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1791-2056 |
2.95e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.75 E-value: 2.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1791 DEIDAAIQRSQQYEQAADAelawVAETKRKLMALGPIRlEQDQTTAQLQVQkafsidiIRHKDSMDELFSHRseifgtCG 1870
Cdd:COG4913 225 EAADALVEHFDDLERAHEA----LEDAREQIELLEPIR-ELAERYAAARER-------LAELEYLRAALRLW------FA 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1871 EEQKTVLQEKTESLIQQYEAisllNSERYARLERAQvlvnqfwetyEELSPWIEETRALIAQlpspaIDHEQLRQQQEEM 1950
Cdd:COG4913 287 QRRLELLEAELEELRAELAR----LEAELERLEARL----------DALREELDELEAQIRG-----NGGDRLEQLEREI 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1951 RQLRESIAEHKPHIDKLLKIGPQLKELNPEEGEMVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPM 2030
Cdd:COG4913 348 ERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAE 427
|
250 260
....*....|....*....|....*.
gi 2245149928 2031 LETLENLSSRlrmpplIPAEVDKIRE 2056
Cdd:COG4913 428 IASLERRKSN------IPARLLALRD 447
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
833-1031 |
2.96e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 43.32 E-value: 2.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 833 RPSRTAAVPTVKDALDAALPSPeegtsiAAVPAPEGTAVVAALVPFPHEdilvasivsleeedVTAAAVSAPeraTVPAV 912
Cdd:PRK07994 360 HPAAPLPEPEVPPQSAAPAASA------QATAAPTAAVAPPQAPAVPPP--------------PASAPQQAP---AVPLP 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 913 TVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEdgtpegpvtpattvhAPEEPDTAAV 992
Cdd:PRK07994 417 ETTSQLLAARQQLQRAQGATKAKKSEPAAASRARPVNSALERLASVRPAPSALEK---------------APAKKEAYRW 481
|
170 180 190
....*....|....*....|....*....|....*....
gi 2245149928 993 RVSTPEEpaSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1031
Cdd:PRK07994 482 KATNPVE--VKKEPVATPKALKKALEHEKTPELAAKLAA 518
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
1121-1184 |
2.98e-03 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 43.13 E-value: 2.98e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 1121 AAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESAS 1184
Cdd:PTZ00144 120 TGGAPPAAAPAAAAAAKAEKTTPEKPKAAAPTPEPPAASKPTPPAAAKPPEPAPAAKPPPTPVA 183
|
|
| EF-hand_6 |
pfam13405 |
EF-hand domain; |
3172-3197 |
3.05e-03 |
|
EF-hand domain;
Pssm-ID: 463869 [Multi-domain] Cd Length: 30 Bit Score: 37.54 E-value: 3.05e-03
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1004-1329 |
3.05e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 43.62 E-value: 3.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1004 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAvpPPEE-------------------PTSPAAAVPTPEeptsPAAAVPtPEE 1064
Cdd:PHA03307 607 AADTGAGAAAPAPAAPRPDAAAAGGASAR--PLREladacvlacravleallegPDGLSAVPGLAF----PRPACP-PRA 679
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1065 PTSPAAAVPT-PEEPTSPAAAVPTPEEPTSPAAAVpTPEEPTSPAAAVPTPEEPASPAaaVPTPEEPASPAAAVPTPEEP 1143
Cdd:PHA03307 680 LEACPARLESwLRELRDLRDAVYLARLRGDLPVAG-GREERVAAVRAVSLVARTVAPL--VRYSPRRARARASAWDITDA 756
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1144 AFPAPAVpTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTpaamvatleeftSPAASVP 1223
Cdd:PHA03307 757 LFSNPSL-VPAKLAEALALLEPAEPQRGAGSSPPVRAEAAFRRPGRLRRSGPAADAASRTA------------SKRKSRS 823
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1224 TSEEPASLAaavsnPEEPTSPAAAVPtleeptsSAAAVLTPEELSSPAASVPTPEEpASPAAAVSNLEEPASPAAAVPTP 1303
Cdd:PHA03307 824 HTPDGGSES-----SGPARPPGAAAR-------PPPARSSESSKSKPAAAGGRARG-KNGRRRPRPPEPRARPGAAAPPK 890
|
330 340
....*....|....*....|....*.
gi 2245149928 1304 EVAAIPAASVPTPEVPAIPAAAVPPM 1329
Cdd:PHA03307 891 AAAAAPPAGAPAPRPRPAPRVKLGPM 916
|
|
| PRK12495 |
PRK12495 |
hypothetical protein; Provisional |
1069-1205 |
3.13e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 183558 [Multi-domain] Cd Length: 226 Bit Score: 42.16 E-value: 3.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1069 AAAVPTPEEPTSPAAAvPTPEEPTSPAAAVPTPEEPTSPAAavptpeepaSPAAAVPTPEEPASPAAAVPTPEEPAfpAP 1148
Cdd:PRK12495 81 GAEATAPSDAGSQASP-DDDAQPAAEAEAADQSAPPEASST---------SATDEAATDPPATAAARDGPTPDPTA--QP 148
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1149 AVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTP 1205
Cdd:PRK12495 149 ATPDERRSPRQRPPVSGEPPTPSTPDAHVAGTLQAARESLVETLARFARRAAATDDP 205
|
|
| PTZ00144 |
PTZ00144 |
dihydrolipoamide succinyltransferase; Provisional |
1108-1174 |
3.16e-03 |
|
dihydrolipoamide succinyltransferase; Provisional
Pssm-ID: 240289 [Multi-domain] Cd Length: 418 Bit Score: 43.13 E-value: 3.16e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1108 AAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPavpTPEESASAAVAVPTPEESASPAA 1174
Cdd:PTZ00144 120 TGGAPPAAAPAAAAAAKAEKTTPEKPKAAAPTPEPPAASKP---TPPAAAKPPEPAPAAKPPPTPVA 183
|
|
| Rib_recp_KP_reg |
pfam05104 |
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards ... |
1076-1159 |
3.19e-03 |
|
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards the C-terminus of the transmembrane domain. The function is unclear.
Pssm-ID: 461548 [Multi-domain] Cd Length: 140 Bit Score: 40.49 E-value: 3.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1076 EEPTSPAAAVPTPEEPTSPAAaVPTPEEPTSPAAAVPTPEEPASPAAAVPTPE-EPASPAAAVPTPEEPAFPAPAVPTPE 1154
Cdd:pfam05104 57 DESEEEPREFKTPDEAPSAAL-EPEPVPTPVPAPVEPEPAPPSESPAPSPKEKkKKEKKSAKVEPAETPEAVQPKPALEK 135
|
....*
gi 2245149928 1155 ESASA 1159
Cdd:pfam05104 136 EEPPA 140
|
|
| EFh_PEF_Group_I |
cd16180 |
Penta-EF hand, calcium binding motifs, found in Group I PEF proteins; The family corresponds ... |
3172-3234 |
3.25e-03 |
|
Penta-EF hand, calcium binding motifs, found in Group I PEF proteins; The family corresponds to Group I PEF proteins that have been found not only in higher animals but also in lower animals, plants, fungi and protists. Group I PEF proteins include apoptosis-linked gene 2 protein (ALG-2), peflin and similar proteins. ALG-2, also termed programmed cell death protein 6 (PDCD6), is a widely expressed calcium-binding modulator protein associated with cell proliferation and death, as well as cell survival. It forms a homodimer in the cell or a heterodimer with its closest paralog peflin. Among the PEF proteins, ALG-2 can bind three Ca2+ ions through its EF1, EF3, and EF5 hands, where it is unique in that its EF5 hand binds Ca2+ ion in a canonical coordination. Peflin is a ubiquitously expressed 30-kD PEF protein containing five EF-hand motifs in its C-terminal domain and a longer N-terminal hydrophobic domain (NHB domain) than any other member of the PEF family. The NHB domain harbors nine repeats of a nonapeptide (A/PPGGPYGGP). Peflin may modulate the function of ALG-2 in Ca2+ signaling. It exists only as a heterodimer with ALG-2, and binds two Ca2+ ions through its EF1 and EF3 hands. Its additional EF5 hand is unpaired and does not bind Ca2+ ion but mediates the heterodimerization with ALG-2. The dissociation of heterodimer occurs in the presence of Ca2+.
Pssm-ID: 320055 [Multi-domain] Cd Length: 164 Bit Score: 40.97 E-value: 3.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 3172 RVMDFFRRIDKDQDGKITRQEF-------------IDGI--LASKFPTT---KLEMT-------------AVADIFDRDG 3220
Cdd:cd16180 1 ELRRIFQAVDRDRSGRISAKELqralsngdwtpfsIETVrlMINMFDRDrsgTINFDefvglwkyiqdwrRLFRRFDRDR 80
|
90
....*....|....
gi 2245149928 3221 DGYIDYYEFVAALH 3234
Cdd:cd16180 81 SGSIDFNELQNALS 94
|
|
| DUF6264 |
pfam19779 |
Family of unknown function (DUF6264); This family of putative integral membrane proteins is ... |
1114-1220 |
3.29e-03 |
|
Family of unknown function (DUF6264); This family of putative integral membrane proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 179 and 218 amino acids in length.
Pssm-ID: 466182 Cd Length: 182 Bit Score: 41.48 E-value: 3.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1114 PEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPeesasPAAAVPTPAE-SASFA------ 1186
Cdd:pfam19779 9 PPGWQRAPIGDPAAAAAAAPPAAPAPAAPAPPAAPAAPPAAPPPPGAPAPGAP-----AAARRARRWDrIATIAllvfgl 83
|
90 100 110
....*....|....*....|....*....|....*
gi 2245149928 1187 -AVVATLEEPTSPAASVPTPAAMvATLEEFTSPAA 1220
Cdd:pfam19779 84 fNVLSSIPSLLDLPSTLQTLFAQ-LGIDEFTPPAA 117
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
1154-1289 |
3.35e-03 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 42.71 E-value: 3.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1154 EESASAAVAVPTPEESASPAAAVPTPAesasfaavvatleePTSPAASVPTPAAMVATleeftsPAASVPTSEEPASLAA 1233
Cdd:PRK10856 153 ELSQNSGQSVPLDTSTTTDPATTPAPA--------------APVDTTPTNSQTPAVAT------APAPAVDPQQNAVVAP 212
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 2245149928 1234 AVSNPeepTSPAAAVPTLEEPTSSAAAVLTPeelsspAASVPTPeePASPAAAVSN 1289
Cdd:PRK10856 213 SQANV---DTAATPAPAAPATPDGAAPLPTD------QAGVSTP--AADPNALVMN 257
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
976-1106 |
3.38e-03 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 42.78 E-value: 3.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 976 TPATTVHAPeePDTAAVRVSTPEEPASPAaavpTPEEPTSPAAAVPTPEEPTSpAAAVPPPEEPTSPAAAVPTPEEPTSP 1055
Cdd:PRK12799 296 HGTVPVAAV--TPSSAVTQSSAITPSSAA----IPSPAVIPSSVTTQSATTTQ-ASAVALSSAGVLPSDVTLPGTVALPA 368
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 2245149928 1056 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTpeEPTS 1106
Cdd:PRK12799 369 AEPVNMQPQPMSTTETQQSSTGNITSTANGPTTSLPAAPASNIPV--SPTS 417
|
|
| DedD |
COG3147 |
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, ... |
1008-1076 |
3.59e-03 |
|
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442381 [Multi-domain] Cd Length: 140 Bit Score: 40.53 E-value: 3.59e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 1008 PTPEEPTSPAAAVpTPEEPtsPAAAVPPPEEPTSPAAAVPTPeeptSPAAAVPTPEEPTSPAAAVPTPE 1076
Cdd:COG3147 1 PAEEAAAAPAAAA-APAAP--AAAAAPAPAAAAAAAAPKPAA----KPAAPKPAAAAAAAPAAKAAAPA 62
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
1192-1314 |
3.75e-03 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 42.78 E-value: 3.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1192 LEEPTSPAASVPTPAAMVATLEEFTSPAASvptseEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPA 1271
Cdd:PRK12799 295 THGTVPVAAVTPSSAVTQSSAITPSSAAIP-----SPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVALPAA 369
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 2245149928 1272 ASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVP 1314
Cdd:PRK12799 370 EPVNMQPQPMSTTETQQSSTGNITSTANGPTTSLPAAPASNIP 412
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
940-1067 |
3.84e-03 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 42.78 E-value: 3.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 940 ITQEGMSAVAGFSPEWAALAITVPITEEDGTPeGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAA 1019
Cdd:PRK12799 293 IDTHGTVPVAAVTPSSAVTQSSAITPSSAAIP-SPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVALPAAEP 371
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 2245149928 1020 VPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTpeEPTS 1067
Cdd:PRK12799 372 VNMQPQPMSTTETQQSSTGNITSTANGPTTSLPAAPASNIPV--SPTS 417
|
|
| EFh |
smart00054 |
EF-hand, calcium binding motif; EF-hands are calcium-binding motifs that occur at least in ... |
3214-3233 |
3.94e-03 |
|
EF-hand, calcium binding motif; EF-hands are calcium-binding motifs that occur at least in pairs. Links between disease states and genes encoding EF-hands, particularly the S100 subclass, are emerging. Each motif consists of a 12 residue loop flanked on either side by a 12 residue alpha-helix. EF-hands undergo a conformational change unpon binding calcium ions.
Pssm-ID: 197492 [Multi-domain] Cd Length: 29 Bit Score: 37.36 E-value: 3.94e-03
|
| EFh |
smart00054 |
EF-hand, calcium binding motif; EF-hands are calcium-binding motifs that occur at least in ... |
3173-3197 |
4.02e-03 |
|
EF-hand, calcium binding motif; EF-hands are calcium-binding motifs that occur at least in pairs. Links between disease states and genes encoding EF-hands, particularly the S100 subclass, are emerging. Each motif consists of a 12 residue loop flanked on either side by a 12 residue alpha-helix. EF-hands undergo a conformational change unpon binding calcium ions.
Pssm-ID: 197492 [Multi-domain] Cd Length: 29 Bit Score: 37.36 E-value: 4.02e-03
|
| half-pint |
TIGR01645 |
poly-U binding splicing factor, half-pint family; The proteins represented by this model ... |
1136-1334 |
4.03e-03 |
|
poly-U binding splicing factor, half-pint family; The proteins represented by this model contain three RNA recognition motifs (rrm: pfam00076) and have been characterized as poly-pyrimidine tract binding proteins associated with RNA splicing factors. In the case of PUF60 (GP|6176532), in complex with p54, and in the presence of U2AF, facilitates association of U2 snRNP with pre-mRNA.
Pssm-ID: 130706 [Multi-domain] Cd Length: 612 Bit Score: 43.14 E-value: 4.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1136 AVPTPEEPAFPAPAVPTPEESASAAVAvptpeesaspAAAVPTPAESASFAAVVA-TLEEPTSPAASVPTPAAMVATLEE 1214
Cdd:TIGR01645 281 CVTPPDALLQPATVSAIPAAAAVAAAA----------ATAKIMAAEAVAGAAVLGpRAQSPATPSSSLPTDIGNKAVVSS 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1215 FTSPAASVPTSeEPASLAAAVSNPEEPTSPAA----AVPTLEEPTSSAAAVLTPEE-LSSPAASVPTPEEPASPAAAVSN 1289
Cdd:TIGR01645 351 AKKEAEEVPPL-PQAAPAVVKPGPMEIPTPVPppglAIPSLVAPPGLVAPTEINPSfLASPRKKMKREKLPVTFGALDDT 429
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2245149928 1290 L--EEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSP 1334
Cdd:TIGR01645 430 LawKEPSKEDQTSEDGKMLAIMGEAAAALALEPKKKKKEKEGEELQP 476
|
|
| PRK05704 |
PRK05704 |
2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase; |
1080-1169 |
4.05e-03 |
|
2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase;
Pssm-ID: 235571 [Multi-domain] Cd Length: 407 Bit Score: 42.51 E-value: 4.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1080 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAvPTPEEPASPAAAVP--------TPEE----PAFPA 1147
Cdd:PRK05704 77 DEGAAAGAAAAAAAAAAAAAAAPAQAQAAAAAEQSNDALSPAAR-KLAAENGLDASAVKgtgkggrvTKEDvlaaLAAAA 155
|
90 100
....*....|....*....|..
gi 2245149928 1148 PAVPTPEESASAAVAVPTPEES 1169
Cdd:PRK05704 156 AAPAAPAAAAPAAAPAPLGARP 177
|
|
| ZipA |
COG3115 |
Cell division protein ZipA, interacts with FtsZ [Cell cycle control, cell division, chromosome ... |
1021-1142 |
4.10e-03 |
|
Cell division protein ZipA, interacts with FtsZ [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442349 [Multi-domain] Cd Length: 298 Bit Score: 42.37 E-value: 4.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1021 PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT------SPAAAVPTPEEPTSPAAAVPTPEeptsp 1094
Cdd:COG3115 38 PSKRDVLLDDDGIGEVRVVAAEAPERVEPEASFDAEDEVREPDQEEvdplldDEADIEAAPAEPVRWAGTAAAVE----- 112
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 2245149928 1095 AAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEE 1142
Cdd:COG3115 113 PAPEQEAYEEAGPAGESAEQEDAPAEEPEAEAPAEEALAAELCAEPEE 160
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
1266-1317 |
4.31e-03 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 43.07 E-value: 4.31e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1266 ELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPE 1317
Cdd:COG5373 36 ELAEAAEAASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPA 87
|
|
| DUF4045 |
pfam13254 |
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. ... |
917-1053 |
4.32e-03 |
|
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. This domain family is found in bacteria and eukaryotes, and is typically between 384 and 430 amino acids in length.
Pssm-ID: 433066 [Multi-domain] Cd Length: 415 Bit Score: 42.46 E-value: 4.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 917 PEGTAAVAAVSSPEETAPAV--AAAITQEGMSAVAGFSPEWAALAITVPITEEdgtpegPVTPATTVHAPEEPDTAAVRV 994
Cdd:pfam13254 214 PGGHSKSPSVSGISADSSPTkeEPSEEADTLSTDKEQSPAPTSASEPPPKTKE------LPKDSEEPAAPSKSAEASTEK 287
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 995 STPEEPASPaaavPTPEEPTSPAAAVPTPeeptSPAAAVPPPEEPTSPAAAVPTPEEPT 1053
Cdd:pfam13254 288 KEPDTESSP----ETSSEKSAPSLLSPVS----KASIDKPLSSPDRDPLSPKPKPQSPP 338
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
1116-1317 |
4.44e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 43.15 E-value: 4.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1116 EPASPAAAVPTPeepaspAAAVPTPEEPAFPAPAVPTPEesasaavavptpeesaspaAAVPTPAESASFAAVVATLEEP 1195
Cdd:PRK10263 318 EPVAVAAAATTA------TQSWAAPVEPVTQTPPVASVD-------------------VPPAQPTVAWQPVPGPQTGEPV 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1196 TSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVP 1275
Cdd:PRK10263 373 IAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQ 452
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2245149928 1276 -TPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPE 1317
Cdd:PRK10263 453 qSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPV 495
|
|
| ftsN |
TIGR02223 |
cell division protein FtsN; FtsN is a poorly conserved protein active in cell division in a ... |
967-1137 |
4.50e-03 |
|
cell division protein FtsN; FtsN is a poorly conserved protein active in cell division in a number of Proteobacteria. The N-terminal 30 residue region tends to by Lys/Arg-rich, and is followed by a membrane-spanning region. This is followed by an acidic low-complexity region of variable length and a well-conserved C-terminal domain of two tandem regions matched by pfam05036 (Sporulation related repeat), found in several cell division and sporulation proteins. The role of FtsN as a suppressor for other cell division mutations is poorly understood; it may involve cell wall hydrolysis. [Cellular processes, Cell division]
Pssm-ID: 274041 [Multi-domain] Cd Length: 298 Bit Score: 41.99 E-value: 4.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 967 EDGTPEGPVTPATT------VHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPtSPAAAVPTPEEPTSPAAAVPPPEEP- 1039
Cdd:TIGR02223 50 ESKQANEPETLQPKnqtengETAADLPPKPEERWSYIEELEAREVLINDPEEP-SNGGGVEESAQLTAEQRQLLEQMQAd 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1040 --TSPAAAVPTPEE----PTSPAAAVPTPEEPTSPAAAVPTPEEpTSPAAAVPTPEEPTSPAAAVPTPeEPTSPAAAVPT 1113
Cdd:TIGR02223 129 mrAAEKVLATAPSEqtvaVEARKQTAEKKPQKARTAEAQKTPVE-TEKIASKVKEAKQKQKALPKQTA-ETQSNSKPIET 206
|
170 180
....*....|....*....|....
gi 2245149928 1114 PEEPASPAAAVPTPEEPASPAAAV 1137
Cdd:TIGR02223 207 APKADKADKTKPKPKEKAERAAAL 230
|
|
| EF-hand_1 |
pfam00036 |
EF hand; The EF-hands can be divided into two classes: signalling proteins and buffering ... |
3214-3233 |
4.58e-03 |
|
EF hand; The EF-hands can be divided into two classes: signalling proteins and buffering/transport proteins. The first group is the largest and includes the most well-known members of the family such as calmodulin, troponin C and S100B. These proteins typically undergo a calcium-dependent conformational change which opens a target binding site. The latter group is represented by calbindin D9k and do not undergo calcium dependent conformational changes.
Pssm-ID: 425435 [Multi-domain] Cd Length: 29 Bit Score: 36.99 E-value: 4.58e-03
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
2341-2911 |
4.65e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 43.03 E-value: 4.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2341 RQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRpisgdpKVIEVELAKHHVLKNDvLAHQATVETVNKAGNELLES 2420
Cdd:TIGR00618 373 QQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQ------ATIDTRTSAFRDLQGQ-LAHAKKQQELQQRYAELCAA 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2421 SAGDDASSLRSRLEAMNQCWESvLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTgglPETAREQLD 2500
Cdd:TIGR00618 446 AITCTAQCEKLEKIHLQESAQS-LKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIH---PNPARQDID 521
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2501 THMELYSQLKAKEETYNQLLDkgrlmllsrddsgSGSKTE-QSVALLEQKWhvvssKMEERKSKLEEALNLATEFQNSLQ 2579
Cdd:TIGR00618 522 NPGPLTRRMQRGEQTYAQLET-------------SEEDVYhQLTSERKQRA-----SLKEQMQEIQQSFSILTQCDNRSK 583
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2580 EFINWLTLAEQslniasppsLILNTVLSQIEEHKVFANEVNAHRDQIIEldQTGNQLKFLSQKQDVVLIKNLLVSVQSRW 2659
Cdd:TIGR00618 584 EDIPNLQNITV---------RLQDLTEKLSEAEDMLACEQHALLRKLQP--EQDLQDVRLHLQQCSQELALKLTALHALQ 652
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2660 EKVVQRSIErgrsldDARKRAKQFHEAWKKLIDWLEDAESHLDSELeiSNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTI 2739
Cdd:TIGR00618 653 LTLTQERVR------EHALSIRVLPKELLASRQLALQKMQSEKEQL--TYWKEMLAQCQTLLRELETHIEEYDREFNEIE 724
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2740 RTGRALKEKtlLPEDSQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQPV-- 2817
Cdd:TIGR00618 725 NASSSLGSD--LAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLlk 802
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2818 --------HGDLDLVMNLMDAHKVFQkelgKRTGTVQVLKRSGRELIENSRDdttwvKGQLQELSTRWDTVCKlsvsKQS 2889
Cdd:TIGR00618 803 tleaeigqEIPSDEDILNLQCETLVQ----EEEQFLSRLEEKSATLGEITHQ-----LLKYEECSKQLAQLTQ----EQA 869
|
570 580
....*....|....*....|..
gi 2245149928 2890 RLEQALKQAEVFRDTVHMLLEW 2911
Cdd:TIGR00618 870 KIIQLSDKLNGINQIKIQFDGD 891
|
|
| DUF3729 |
pfam12526 |
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ... |
1165-1251 |
4.97e-03 |
|
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.
Pssm-ID: 372164 [Multi-domain] Cd Length: 115 Bit Score: 39.68 E-value: 4.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1165 TPEESASPAAAVPTPAESAsFAAVVATLEEPTSPAASVPTPAAMVATL----EEFTSPAASVPTSEEPASLAAAVsnpeE 1240
Cdd:pfam12526 17 TRTWSTSGFSSCFSPPESA-HPDPPPPVGDPRPPVVDTPPPVSAVWVLpppsEPAAPEPDLVPPVTGPAGPPSPL----A 91
|
90
....*....|.
gi 2245149928 1241 PTSPAAAVPTL 1251
Cdd:pfam12526 92 PPAPAQKPPLP 102
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
1020-1086 |
4.99e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 42.81 E-value: 4.99e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1020 VPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1086
Cdd:PRK14965 381 APAPPSAAWGAPTPAAPAAPPPAAAPPVPPAAPARPAAARPAPAPAPPAAAAPPARSADPAAAASAG 447
|
|
| Rib_recp_KP_reg |
pfam05104 |
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards ... |
982-1065 |
5.05e-03 |
|
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards the C-terminus of the transmembrane domain. The function is unclear.
Pssm-ID: 461548 [Multi-domain] Cd Length: 140 Bit Score: 40.10 E-value: 5.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 982 HAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPT-SPAAAVPTPEEPTSPAAAVP 1060
Cdd:pfam05104 53 SEQADESEEEPREFKTPDEAPSAALEPEPVPTPVPAPVEPEPAPPSESPAPSPKEKKKKeKKSAKVEPAETPEAVQPKPA 132
|
....*
gi 2245149928 1061 TPEEP 1065
Cdd:pfam05104 133 LEKEE 137
|
|
| motB |
PRK05996 |
MotB family protein; |
1218-1312 |
5.09e-03 |
|
MotB family protein;
Pssm-ID: 235665 [Multi-domain] Cd Length: 423 Bit Score: 42.38 E-value: 5.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1218 PAASVPTSEEPASLAAAVSnPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPA 1297
Cdd:PRK05996 193 TTAGDLLPPGQAREQAQGA-KSATAAPATVPQAAPLPQAQPKKAATEEELIADAKKAATGEPAANAAKAAKPEPMPDDQQ 271
|
90
....*....|....*
gi 2245149928 1298 AAVPTPEVAAIPAAS 1312
Cdd:PRK05996 272 KEAEQLQAAIAQAIG 286
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
1144-1276 |
5.11e-03 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 42.65 E-value: 5.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1144 AFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAA-VVATLEEPTSPAASVPTPAAMVATLEEFTSPAASV 1222
Cdd:PRK06995 42 ALADSDLAALAPPAAAAPAAAQPPPAAAPAAVSRPAAPAAEPAPwLVEHAKRLTAQREQLVARAAAPAAPEAQAPAAPAE 121
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 1223 PTSEEPASLAAAvsnPEEPTSPAAAVPtleeptSSAAAVLTPEELSSPAASVPT 1276
Cdd:PRK06995 122 RAAAENAARRLA---RAAAAAPRPRVP------ADAAAAVADAVKARIERIVND 166
|
|
| SAV_2336_NTERM |
NF041121 |
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ... |
958-1051 |
5.27e-03 |
|
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.
Pssm-ID: 469044 [Multi-domain] Cd Length: 473 Bit Score: 42.30 E-value: 5.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 958 LAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPeePASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPE 1037
Cdd:NF041121 11 LAAQMGRAAAPPSPEGPAPTAASQPATPPPPAAPPSPPGD--PPEPPAPEPAPLPAPYPGSLAPPPPPPPGPAGAAPGAA 88
|
90
....*....|....*.
gi 2245149928 1038 EP-TSPAAAV-PTPEE 1051
Cdd:NF041121 89 LPvRVPAPPAlPNPLE 104
|
|
| SAV_2336_NTERM |
NF041121 |
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ... |
1105-1183 |
5.27e-03 |
|
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.
Pssm-ID: 469044 [Multi-domain] Cd Length: 473 Bit Score: 42.30 E-value: 5.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1105 TSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEE---PAFPAPaVPTPEESASAAVAVPTPE-ESASPAAAVP--T 1178
Cdd:NF041121 15 MGRAAAPPSPEGPAPTAASQPATPPPPAAPPSPPGDPPeppAPEPAP-LPAPYPGSLAPPPPPPPGpAGAAPGAALPvrV 93
|
....*
gi 2245149928 1179 PAESA 1183
Cdd:NF041121 94 PAPPA 98
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
1148-1259 |
5.61e-03 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 42.40 E-value: 5.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1148 PAVPTPEESASAAVAVPTPEESASPA-AAVPTPAESASFAAVVATleePTSPAASVPTPAAMVATLEEFTSPAASVPTSE 1226
Cdd:PRK12799 300 PVAAVTPSSAVTQSSAITPSSAAIPSpAVIPSSVTTQSATTTQAS---AVALSSAGVLPSDVTLPGTVALPAAEPVNMQP 376
|
90 100 110
....*....|....*....|....*....|...
gi 2245149928 1227 EPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAA 1259
Cdd:PRK12799 377 QPMSTTETQQSSTGNITSTANGPTTSLPAAPAS 409
|
|
| Rib_recp_KP_reg |
pfam05104 |
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards ... |
1060-1144 |
5.66e-03 |
|
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards the C-terminus of the transmembrane domain. The function is unclear.
Pssm-ID: 461548 [Multi-domain] Cd Length: 140 Bit Score: 40.10 E-value: 5.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1060 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPtSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPT 1139
Cdd:pfam05104 55 QADESEEEPREFKTPDEAPSAALEPEPVPTPVPAPVEPEPAPPSE-SPAPSPKEKKKKEKKSAKVEPAETPEAVQPKPAL 133
|
....*
gi 2245149928 1140 PEEPA 1144
Cdd:pfam05104 134 EKEEP 138
|
|
| EFh_CREC_Calumenin_like |
cd16226 |
EF-hand, calcium binding motif, found in calumenin, reticulocalbin-1 (RCN-1), reticulocalbin-3 ... |
3177-3238 |
5.68e-03 |
|
EF-hand, calcium binding motif, found in calumenin, reticulocalbin-1 (RCN-1), reticulocalbin-3 (RCN-3), and similar proteins; The family corresponds to a group of six EF-hand Ca2+-binding proteins, including calumenin (also known as crocalbin or CBP-50), reticulocalbin-1 (RCN-1), reticulocalbin-3 (RCN-3), and similar proteins. Calumenin is an endo/sarcoplasmic reticulum (ER/SR) resident low-affinity Ca2+-binding protein that contains six EF-hand domains and a C-terminal SR retention signal His-Asp-Glu-Phe (HDEF) tetrapeptide. It functions as a novel regulator of SERCA2, and its expressional changes are tightly coupled with Ca2+-cycling of cardiomyocytes. It is also broadly involved in haemostasis and in the pathophysiology of thrombosis. Moreover, the extracellular calumenin acts as a suppressor of cell migration and tumor metastasis. RCN-1 is an endoplasmic reticulum resident Ca2+-binding protein with a carboxyl-terminal His-Asp-Glu-Leu (HDEL) tetrapeptide signal. It acts as a potential negative regulator of B-RAF activation and can negatively modulate cardiomyocyte hypertrophy by inhibition of the mitogen-activated protein kinase signalling cascade. It also plays a key role in the development of doxorubicin-associated resistance. RCN-3 is a putative six EF-hand Ca2+-binding protein that contains five RXXR (X is any amino acid) motifs and a C-terminal ER retrieval signal HDEL tetrapeptide. The RXXR motif represents the target sequence of subtilisin-like proprotein convertases (SPCs). RCN-3 is specifically bound to the paired basic amino-acid-cleaving enzyme-4 (PACE4) precursor protein and plays an important role in the biosynthesis of PACE4.
Pssm-ID: 320024 [Multi-domain] Cd Length: 264 Bit Score: 41.42 E-value: 5.68e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2245149928 3177 FRRIDKDQDGKITRQEFIDGILASKFPTTK--LEMTAVADIfDRDGDGYIDYYEFVAALHPNKD 3238
Cdd:cd16226 125 WKAADQDGDGKLTKEEFTAFLHPEEFPHMRdiVVQETLEDI-DKNKDGFISLEEYIGDMYRDDD 187
|
|
| PRK05035 |
PRK05035 |
electron transport complex protein RnfC; Provisional |
998-1236 |
5.73e-03 |
|
electron transport complex protein RnfC; Provisional
Pssm-ID: 235334 [Multi-domain] Cd Length: 695 Bit Score: 42.63 E-value: 5.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 998 EEPASPAAAVPTPEEPTSPAAAVptpeeptSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1077
Cdd:PRK05035 470 EARHKKAAEARAAKDKDAVAAAL-------ARVKAKKAAATQPIVIKAGARPDNSAVIAAREARKAQARARQAEKQAAAA 542
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1078 PTSPAAAVptpeeptspAAAVPTPE----EPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTP 1153
Cdd:PRK05035 543 ADPKKAAV---------AAAIARAKakkaAQQAANAEAEEEVDPKKAAVAAAIARAKAKKAAQQAASAEPEEQVAEVDPK 613
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1154 EESASAAVAVPTPEESASPAAAVPTPAESASFAAVvatleeptspAASVPTPAAMVATLEEFTSPAASvPTSEEPASLAA 1233
Cdd:PRK05035 614 KAAVAAAIARAKAKKAEQQANAEPEEPVDPRKAAV----------AAAIARAKARKAAQQQANAEPEE-AEDPKKAAVAA 682
|
...
gi 2245149928 1234 AVS 1236
Cdd:PRK05035 683 AIA 685
|
|
| PRK10118 |
PRK10118 |
flagellar hook length control protein FliK; |
993-1183 |
5.84e-03 |
|
flagellar hook length control protein FliK;
Pssm-ID: 236652 [Multi-domain] Cd Length: 408 Bit Score: 42.16 E-value: 5.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 993 RVSTPEEPASPAAAVPTPEEPTSPAAavpTPEEPTSPAAAVPPPEEPTSPAAAVpTPEE-----------PTSPAAAVPT 1061
Cdd:PRK10118 85 QQANLLIPVDETLPVITDEQSLSSPL---TPALKTSALAALSKNAQKDEKADDL-SDEDlaslsalfamlPGQDNTTPVA 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1062 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPtpeePTSPAAAVPTPEEPASPAAAvptpeePASPAAAVPTPE 1141
Cdd:PRK10118 161 DAPSTVLPAEKPTLLTKDMPSAPQDETHTLSSDEHEKG----LTSAQLTTAQPDDAPGTPAQ------PLTPLAAEAQAK 230
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2245149928 1142 EPAFpapAVPTPEESASAAVAVPTpeeSASPAAAVPTPAESA 1183
Cdd:PRK10118 231 AEVI---STPSPVTAAASPTITPH---QTQPLPTAAAPVLSA 266
|
|
| PRK12373 |
PRK12373 |
NADH-quinone oxidoreductase subunit E; |
1052-1180 |
5.97e-03 |
|
NADH-quinone oxidoreductase subunit E;
Pssm-ID: 237082 [Multi-domain] Cd Length: 400 Bit Score: 42.10 E-value: 5.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1052 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPeepaSPAAAVPTPeEPA 1131
Cdd:PRK12373 194 LTSLTEEAGKARYNASKALAEDIGDTVKRIDGTEVPLLAPWQGDAAPVPPSEAARPKSADAET----NAALKTPAT-APK 268
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1132 SPAAAVPTPEEPAFPAPAVPTP---EESASAAVAVPTPEESASPAAAVPTPA 1180
Cdd:PRK12373 269 AAAKNAKAPEAQPVSGTAAAEPapkEAAKAAAAAAKPALEDKPRPLGIARPG 320
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
1186-1315 |
6.06e-03 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 42.26 E-value: 6.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1186 AAVVATLeePTSPAASVPTPAAMVAtleefTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPE 1265
Cdd:PRK06995 49 AALAPPA--AAAPAAAQPPPAAAPA-----AVSRPAAPAAEPAPWLVEHAKRLTAQREQLVARAAAPAAPEAQAPAAPAE 121
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1266 ELSSPAASVPTPEEPASPAAAvsnleEPASPAAAVPTPEVAAIPAASVPT 1315
Cdd:PRK06995 122 RAAAENAARRLARAAAAAPRP-----RVPADAAAAVADAVKARIERIVND 166
|
|
| ZipA |
COG3115 |
Cell division protein ZipA, interacts with FtsZ [Cell cycle control, cell division, chromosome ... |
1060-1183 |
6.08e-03 |
|
Cell division protein ZipA, interacts with FtsZ [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442349 [Multi-domain] Cd Length: 298 Bit Score: 41.60 E-value: 6.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1060 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEptspAAAVPTPEEPASPAAAVPTPEEPASPAAAV-P 1138
Cdd:COG3115 38 PSKRDVLLDDDGIGEVRVVAAEAPERVEPEASFDAEDEVREPDQ----EEVDPLLDDEADIEAAPAEPVRWAGTAAAVeP 113
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 2245149928 1139 TPEEPAFpAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESA 1183
Cdd:COG3115 114 APEQEAY-EEAGPAGESAEQEDAPAEEPEAEAPAEEALAAELCAE 157
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
1220-1313 |
6.16e-03 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 41.94 E-value: 6.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1220 ASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAvsnleePASPAAA 1299
Cdd:PRK10856 168 TTTDPATTPAPAAPVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPSQANVDTAATPAPAAPATPDGA------APLPTDQ 241
|
90
....*....|....
gi 2245149928 1300 VPTPEVAAIPAASV 1313
Cdd:PRK10856 242 AGVSTPAADPNALV 255
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
1066-1182 |
6.22e-03 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 42.01 E-value: 6.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1066 TSPAAAvPTPEEPTSPAAAVPTPEEPTSPAAAVPTPeePTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAF 1145
Cdd:PRK12799 298 TVPVAA-VTPSSAVTQSSAITPSSAAIPSPAVIPSS--VTTQSATTTQASAVALSSAGVLPSDVTLPGTVALPAAEPVNM 374
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 2245149928 1146 PAPAVPTPEESASAAVAV------PTPEESASPAAAVPTPAES 1182
Cdd:PRK12799 375 QPQPMSTTETQQSSTGNItstangPTTSLPAAPASNIPVSPTS 417
|
|
| PRK14954 |
PRK14954 |
DNA polymerase III subunits gamma and tau; Provisional |
967-1098 |
6.26e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184918 [Multi-domain] Cd Length: 620 Bit Score: 42.24 E-value: 6.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 967 EDGTPEGPVTPATTV------HAPEEPDTAAVRVSTPEEPASPAAavpTPEEPTSPAAAvPTPEE-PTSPaaavPPPEEP 1039
Cdd:PRK14954 372 ELVRNDGGVAPSPAGspdvkkKAPEPDLPQPDRHPGPAKPEAPGA---RPAELPSPASA-PTPEQqPPVA----RSAPLP 443
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 1040 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1098
Cdd:PRK14954 444 PSPQASAPRNVASGKPGVDLGSWQGKFMNFTRNGSRKQPVQASSSDAAQTGVFEGVAEL 502
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
852-1009 |
6.34e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 42.39 E-value: 6.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 852 PSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASivsleeedVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEE 931
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAP--------APAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAA 437
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2245149928 932 TAPAVAAAITQEGMSAVAgfSPEWAALAITVpiteedgTPEGPVTPAttvHAPEEPDTAAVRVSTPEEPASPAAAVPT 1009
Cdd:PRK14951 438 PAAAPAAVALAPAPPAQA--APETVAIPVRV-------APEPAVASA---APAPAAAPAAARLTPTEEGDVWHATVQQ 503
|
|
| EFh_CREC |
cd15899 |
EF-hand, calcium binding motif, found in CREC-EF hand family; The CREC (Cab45/reticulocalbin ... |
3129-3251 |
6.36e-03 |
|
EF-hand, calcium binding motif, found in CREC-EF hand family; The CREC (Cab45/reticulocalbin/ERC45/calumenin)-EF hand family contains a group of six EF-hand, low-affinity Ca2+-binding proteins, including reticulocalbin (RCN-1), ER Ca2+-binding protein of 55 kDa (ERC-55, also known as TCBP-49 or E6BP), reticulocalbin-3 (RCN-3), Ca2+-binding protein of 45 kDa (Cab45 and its splice variant Cab45b), and calumenin ( also known as crocalbin or CBP-50). The proteins are not only localized in various parts of the secretory pathway, but also found in the cytosolic compartment and at the cell surface. They interact with different ligands or proteins and have been implicated in the secretory process, chaperone activity, signal transduction as well as in a large variety of disease processes.
Pssm-ID: 320021 [Multi-domain] Cd Length: 267 Bit Score: 41.66 E-value: 6.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 3129 LALERQRKlndaldRLEELKEFANFDFDVW--RKKYMRWMNHK-KSRVMD----FFRRIDKDQDGKITRQEFIDGILASK 3201
Cdd:cd15899 28 LTPEESKR------RLGVIVSKMDVDKDGFisAKELHSWILESfKRHAMEeskeQFRAVDPDEDGHVSWDEYKNDTYGSV 101
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 3202 FPTTKLEMTAVADIF----------------DRDGDGYIDYYEFVAALHPNKDAY-RPTTDADKIED 3251
Cdd:cd15899 102 GDDEENVADNIKEDEeykklllkdkkrfeaaDQDGDLILTLEEFLAFLHPEESPYmLDFVIKETLED 168
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1871-2338 |
6.37e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 42.31 E-value: 6.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1871 EEQKTVLQEKTESLIQqyeaISLLNSERYARLERAQVLVNQFWETYEELSPWIEETRALIAQLPSPAID------HEQLR 1944
Cdd:TIGR04523 242 NEKTTEISNTQTQLNQ----LKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQdwnkelKSELK 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1945 QQQEEMRQLRESIAEHKPHIDKLLKIGPQL-KELNPEEGEMVEEKYQKAENMyAQIKEEVRQRALALDEAVSQSTQITEF 2023
Cdd:TIGR04523 318 NQEKKLEEIQNQISQNNKIISQLNEQISQLkKELTNSESENSEKQRELEEKQ-NEIEKLKKENQSYKQEIKNLESQINDL 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2024 HDKIEPMLETLENLSSRLRM----PPLIPAEVDKIRECISDNKSATVELEK----LQPSFEALKRRGEELigRSQGADKD 2095
Cdd:TIGR04523 397 ESKIQNQEKLNQQKDEQIKKlqqeKELLEKEIERLKETIIKNNSEIKDLTNqdsvKELIIKNLDNTRESL--ETQLKVLS 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2096 LAAKEIQDKLDQMVffwedikaraEEREIKFLDVLELAEKfwydmaallttIKDTQDIVHDLESPgIDPSIIKQQVEAAE 2175
Cdd:TIGR04523 475 RSINKIKQNLEQKQ----------KELKSKEKELKKLNEE-----------KKELEEKVKDLTKK-ISSLKEKIEKLESE 532
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2176 --TIKEETDGLHEELEFIRilgADLIFACGETEKPEVRKSIDEMNNAWENLNKTWKERLEKLEdamqaavQYQDtlqamf 2253
Cdd:TIGR04523 533 kkEKESKISDLEDELNKDD---FELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELID-------QKEK------ 596
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2254 dwldntviklctmppvgtDLNTVKDQLnEMKEFKVEVYQQQIE-MEKLNHQGELMLKK---ATDETDRDI--IREPLTEL 2327
Cdd:TIGR04523 597 ------------------EKKDLIKEI-EEKEKKISSLEKELEkAKKENEKLSSIIKNiksKKNKLKQEVkqIKETIKEI 657
|
490
....*....|.
gi 2245149928 2328 KHLWENLGEKI 2338
Cdd:TIGR04523 658 RNKWPEIIKKI 668
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1464-2085 |
6.68e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 42.26 E-value: 6.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1464 AQLQEALLHC--GKFQDALEPLLSWLADTEELIANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIA-- 1539
Cdd:TIGR00618 203 SQLLTLCTPCmpDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEet 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1540 --------QSAELA-----------DREKITGQLESLESRWTELLSKAAARQKQ---LEDILVLAKQFHETAEPISD--- 1594
Cdd:TIGR00618 283 qerinrarKAAPLAahikavtqieqQAQRIHTELQSKMRSRAKLLMKRAAHVKQqssIEEQRRLLQTLHSQEIHIRDahe 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1595 ----FLSVTEKKLANSEPVgtqtaKIQQQIIRHKALNEEIVNRKKNVDQAIKNGQA--LLKQTTGEEVLLIQEKLDGIKT 1668
Cdd:TIGR00618 363 vatsIREISCQQHTLTQHI-----HTLQQQKTTLTQKLQSLCKELDILQREQATIDtrTSAFRDLQGQLAHAKKQQELQQ 437
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1669 RYADI-TVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELATsggQSPTGEQIPQFQQRQKELKKEVmEHRLVLD 1747
Cdd:TIGR00618 438 RYAELcAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQ---ETRKKAVVLARLLELQEEPCPL-CGSCIHP 513
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1748 TVNEVSRALLELVPWRAREGLD--KLVSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLmaLG 1825
Cdd:TIGR00618 514 NPARQDIDNPGPLTRRMQRGEQtyAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNL--QN 591
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1826 PIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELfSHRSEIFGTCGEEQKTVLQEKT------ESLIQQYEAISLLNSERY 1899
Cdd:TIGR00618 592 ITVRLQDLTEKLSEAEDMLACEQHALLRKLQPE-QDLQDVRLHLQQCSQELALKLTalhalqLTLTQERVREHALSIRVL 670
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1900 AR--LERAQVLVNQFWETYEELSPWIEEtraliaqlpspaidheqLRQQQEEMRQLRESIAEHKPHIDKL-LKIGPQLKE 1976
Cdd:TIGR00618 671 PKelLASRQLALQKMQSEKEQLTYWKEM-----------------LAQCQTLLRELETHIEEYDREFNEIeNASSSLGSD 733
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1977 LNPEEgEMVEEKYQKAENMY-AQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRMPPLIPAEVDKIR 2055
Cdd:TIGR00618 734 LAARE-DALNQSLKELMHQArTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEI 812
|
650 660 670
....*....|....*....|....*....|
gi 2245149928 2056 EciSDNKSATVELEKLQPSFEALKRRGEEL 2085
Cdd:TIGR00618 813 P--SDEDILNLQCETLVQEEEQFLSRLEEK 840
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
1097-1317 |
6.71e-03 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 42.06 E-value: 6.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1097 AVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAV---PTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPA 1173
Cdd:NF033839 139 AVSKFEKDSSSSSSSGSSTKPETPQPENPEHQKPTTPAPDTkpsPQPEGKKPSVPDINQEKEKAKLAVATYMSKILDDIQ 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1174 AAVPTPAESASFAAVVATLEEPTSPAAS-VPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLE 1252
Cdd:NF033839 219 KHHLQKEKHRQIVALIKELDELKKQALSeIDNVNTKVEIENTVHKIFADMDAVVTKFKKGLTQDTPKEPGNKKPSAPKPG 298
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1253 EPTSSAaavlTPEELSSPAASVPTPE---EPASPAAAVSnlEEPASPAAAVP----TPEVAAIPAASVPTPE 1317
Cdd:NF033839 299 MQPSPQ----PEKKEVKPEPETPKPEvkpQLEKPKPEVK--PQPEKPKPEVKpqleTPKPEVKPQPEKPKPE 364
|
|
| DedD |
COG3147 |
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, ... |
1117-1183 |
7.20e-03 |
|
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442381 [Multi-domain] Cd Length: 140 Bit Score: 39.76 E-value: 7.20e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1117 PASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAavAVPTPEESASPAAAVPTPAESA 1183
Cdd:COG3147 1 PAEEAAAAPAAAAAPAAPAAAAAPAPAAAAAAAAPKPAAKPAA--PKPAAAAAAAPAAKAAAPAGGG 65
|
|
| sucB |
TIGR01347 |
2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component); This ... |
1026-1125 |
7.35e-03 |
|
2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component); This model describes the TCA cycle 2-oxoglutarate system E2 component, dihydrolipoamide succinyltransferase. It is closely related to the pyruvate dehydrogenase E2 component, dihydrolipoamide acetyltransferase. The seed for this model includes mitochondrial and Gram-negative bacterial forms. Mycobacterial candidates are highly derived, differ in having and extra copy of the lipoyl-binding domain at the N-terminus. They score below the trusted cutoff, but above the noise cutoff and above all examples of dihydrolipoamide acetyltransferase. [Energy metabolism, TCA cycle]
Pssm-ID: 273565 [Multi-domain] Cd Length: 403 Bit Score: 41.64 E-value: 7.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1026 PTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPE---EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAvptpe 1102
Cdd:TIGR01347 81 TAAPPAKSGEEKEETPAASAAAAPTAAANRPSLSPAARrlaKEHGIDLSAVPGTGVTGRVTKEDIIKKTEAPASA----- 155
|
90 100
....*....|....*....|...
gi 2245149928 1103 EPTSPAAAVPTPEEPASPAAAVP 1125
Cdd:TIGR01347 156 QPPAAAAAAAAPAAATRPEERVK 178
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
834-965 |
7.55e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 42.17 E-value: 7.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 834 PSRTAAVP--TVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVA-SIVSLEEED-----VTAAAVSAPE 905
Cdd:PRK12323 451 APAPAAAPaaAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEfASPAPAQPDaapagWVAESIPDPA 530
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2245149928 906 RATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAG-FSPEWAALAITVPIT 965
Cdd:PRK12323 531 TADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDmFDGDWPALAARLPVR 591
|
|
| EFh_CREC |
cd15899 |
EF-hand, calcium binding motif, found in CREC-EF hand family; The CREC (Cab45/reticulocalbin ... |
3170-3257 |
7.73e-03 |
|
EF-hand, calcium binding motif, found in CREC-EF hand family; The CREC (Cab45/reticulocalbin/ERC45/calumenin)-EF hand family contains a group of six EF-hand, low-affinity Ca2+-binding proteins, including reticulocalbin (RCN-1), ER Ca2+-binding protein of 55 kDa (ERC-55, also known as TCBP-49 or E6BP), reticulocalbin-3 (RCN-3), Ca2+-binding protein of 45 kDa (Cab45 and its splice variant Cab45b), and calumenin ( also known as crocalbin or CBP-50). The proteins are not only localized in various parts of the secretory pathway, but also found in the cytosolic compartment and at the cell surface. They interact with different ligands or proteins and have been implicated in the secretory process, chaperone activity, signal transduction as well as in a large variety of disease processes.
Pssm-ID: 320021 [Multi-domain] Cd Length: 267 Bit Score: 41.27 E-value: 7.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 3170 KSRVMDFFRRIDKDQDGKITRQEFIDGILASkfpTTKLEMTAVADIF---DRDGDGYIDYYEFVAALHPNKDAYRPTTDA 3246
Cdd:cd15899 34 KRRLGVIVSKMDVDKDGFISAKELHSWILES---FKRHAMEESKEQFravDPDEDGHVSWDEYKNDTYGSVGDDEENVAD 110
|
90
....*....|.
gi 2245149928 3247 DKIEDEVTRQV 3257
Cdd:cd15899 111 NIKEDEEYKKL 121
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
3332-3513 |
8.03e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 42.08 E-value: 8.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 3332 PEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVIPSSGSKLKRPTPTFHSSRTSlA 3411
Cdd:PHA03307 242 SESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSS-S 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 3412 GDTSNSSSPASTGAKtnRADPKKSASRPGSRAGSRAGSRASSRRGSDASdfdlleTQSACSDTSESSAAGGQGNSRRGLN 3491
Cdd:PHA03307 321 SRESSSSSTSSSSES--SRGAAVSPGPSPSRSPSPSRPPPPADPSSPRK------RPRPSRAPSSPAASAGRPTRRRARA 392
|
170 180
....*....|....*....|....
gi 2245149928 3492 KPSKIPTMSKKT--TTASPRTPGP 3513
Cdd:PHA03307 393 AVAGRARRRDATgrFPAGRPRPSP 416
|
|
| PRK12373 |
PRK12373 |
NADH-quinone oxidoreductase subunit E; |
1022-1149 |
8.07e-03 |
|
NADH-quinone oxidoreductase subunit E;
Pssm-ID: 237082 [Multi-domain] Cd Length: 400 Bit Score: 41.71 E-value: 8.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1022 TPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP-TSPAAAVP--TPEEPTSPAAAv 1098
Cdd:PRK12373 198 TEEAGKARYNASKALAEDIGDTVKRIDGTEVPLLAPWQGDAAPVPPSEAARPKSADAeTNAALKTPatAPKAAAKNAKA- 276
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 2245149928 1099 PTPEEPTSPAAAVPTPEEPASPAAavptpeEPASPAAAV-PTPEEPAFPAPA 1149
Cdd:PRK12373 277 PEAQPVSGTAAAEPAPKEAAKAAA------AAAKPALEDkPRPLGIARPGGA 322
|
|
| PDHac_trf_long |
TIGR01348 |
pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; This model ... |
929-1134 |
8.28e-03 |
|
pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; This model describes a subset of pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase specifically close by both phylogenetic and per cent identity (UPGMA) trees. Members of this set include two or three copies of the lipoyl-binding domain. E. coli AceF is a member of this model, while mitochondrial and some other bacterial forms belong to a separate model. [Energy metabolism, Pyruvate dehydrogenase]
Pssm-ID: 273566 [Multi-domain] Cd Length: 546 Bit Score: 41.78 E-value: 8.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 929 PEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEePASPAAAvP 1008
Cdd:TIGR01348 23 PGDKVEAGQSLITLESDKASMEVPSSAAGIIKEIKVKVGDTLPVGGVIATLEVGAGAQAQAEAKKEAAPA-PTAGAPA-P 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1009 TPEEPTSPAAAVPTP-EEPTSP----AAAVPPPE------------------EPTSPAAAVPTPEEPTSPAAAVPTPEE- 1064
Cdd:TIGR01348 101 AAQAQAAPAAGQSSGvQEVTVPdigdIEKVTVIEvlvkvgdtvsadqslitlESDKASMEVPAPASGVVKSVKVKVGDSv 180
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1065 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPA 1134
Cdd:TIGR01348 181 PTGDLILTLSVAGSTPATAPAPASAQPAAQSPAATQPEPAAAPAAAKAQAPAPQQAGTQNPAKVDHAAPA 250
|
|
| PRK06975 |
PRK06975 |
bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed |
1095-1161 |
8.40e-03 |
|
bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed
Pssm-ID: 235899 [Multi-domain] Cd Length: 656 Bit Score: 42.01 E-value: 8.40e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245149928 1095 AAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAV 1161
Cdd:PRK06975 260 RAFLTWADAAAQPATAAPAPSRMTDTNDSKSVTSQPAAAAAAPAPPPNPPATPPEPPARRGRGSAAL 326
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
1049-1166 |
8.45e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 42.07 E-value: 8.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1049 PEEPTSPAAAVPTPEEPTsPAAAVPTPEEPTSPAAavPTPEEPTSPAAAVPTPEE-PTSPAAAVPTPEEPASPAAAVPTP 1127
Cdd:PRK14971 375 PKQHIKPVFTQPAAAPQP-SAAAAASPSPSQSSAA--AQPSAPQSATQPAGTPPTvSVDPPAAVPVNPPSTAPQAVRPAQ 451
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2245149928 1128 EEPASPAAAVPTP-EEPAFPAPAVPTPEESASAAVAVPTP 1166
Cdd:PRK14971 452 FKEEKKIPVSKVSsLGPSTLRPIQEKAEQATGNIKEAPTG 491
|
|
| EFh_PI-PLC |
cd15898 |
EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4. ... |
3172-3234 |
8.54e-03 |
|
EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes; PI-PLC isozymes are signaling enzymes that hydrolyze the membrane phospholipids phosphatidylinositol-4,5-bisphosphate (PIP2) to generate two important second messengers in eukaryotic signal transduction cascades, Inositol 1,4,5-trisphosphate (InsP3) and diacylglycerol (DAG). InsP3 triggers inflow of calcium from intracellular stores, while DAG, together with calcium, activates protein kinase C, which goes on to phosphorylate other molecules, leading to altered cellular activity. Calcium is required for the catalysis. This family corresponds to the four EF-hand motifs containing PI-PLC isozymes, including PI-PLC-beta (1-4), -gamma (1-2), -delta (1,3,4), -epsilon (1), -zeta (1), eta (1-2). Lower eukaryotes such as yeast and slime molds contain only delta-type isozymes. In contrast, other types of isoforms present in higher eukaryotes. This family also includes 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1 (PLC1) from fungi. Some homologs from plants contain only two atypical EF-hand motifs and they are not included. All PI-PLC isozymes except sperm-specific PI-PLC-zeta share a core set of domains, including an N-terminal pleckstrin homology (PH) domain, four atypical EF-hand motifs, a PLC catalytic core, and a single C2 domain. PI-PLC-zeta lacks the PH domain. The PLC catalytic core domain is a TIM barrel with two highly conserved regions (X and Y) split by a highly degenerate linker sequence. Most of EF-hand motifs found in PI-PLCs consist of a helix-loop-helix structure, but lack residues critical to metal binding. Moreover, the EF-hand region of most of PI-PLCs may have an important regulatory function, but it has yet to be identified. However, PI-PLC-zeta is a key exception. It is responsible for Ca2+ oscillations in fertilized oocytes and exhibits a high sensitivity to Ca2+ mediated through its EF-hand domain. In addition, PI-PLC-eta2 shows a canonical EF-loop directing Ca2+-sensitivity and thus can amplify transient Ca2+ signals. Also it appears that PI-PLC-delta1 can regulate the binding of PH domain to PIP2 in a Ca2+-dependent manner through its functionally important EF-hand domains. PI-PLCs can be activated by a variety of extracellular ligands, such as growth factors, hormones, cytokines and lipids. Their activation has been implicated in tumorigenesis and/or metastasis linked to migration, proliferation, growth, inflammation, angiogenesis and actin cytoskeleton reorganization. PI-PLC-beta isozymes are activated by G-protein coupled receptor (GPCR) through different mechanisms. However, PI-PLC-gamma isozymes are activated by receptor tyrosine kinase (RTK), such as Rho and Ras GTPases. In contrast, PI-PLC-epsilon are activated by both GPCR and RTK. PI-PLC-delta1 and PLC-eta 1 are activated by GPCR-mediated calcium mobilization. The activation mechanism for PI-PLC-zeta remains unclear.
Pssm-ID: 320029 [Multi-domain] Cd Length: 137 Bit Score: 39.19 E-value: 8.54e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 3172 RVMDFFRRIDKDQDGKITRQEF---IDGILaskFPTTKLEmtaVADIF---DRDGDGYIDYYEFVAALH 3234
Cdd:cd15898 1 WLRRQWIKADKDGDGKLSLKEIkklLKRLN---IRVSEKE---LKKLFkevDTNGDGTLTFDEFEELYK 63
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
885-1025 |
8.60e-03 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 41.29 E-value: 8.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 885 VASIVSLE--EEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGmSAVAGFSPEWAALAITV 962
Cdd:NF040712 199 LATVPRLArePADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPV-GPGAAPAAEPDEATRDA 277
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 963 PITEEDGTPEGPVTPATTVHAPEEPDTAAVRVstPEEPASPAAAVPTPEEPTSPAAAVPTPEE 1025
Cdd:NF040712 278 GEPPAPGAAETPEAAEPPAPAPAAPAAPAAPE--AEEPARPEPPPAPKPKRRRRRASVPSWDD 338
|
|
| PHA03369 |
PHA03369 |
capsid maturational protease; Provisional |
983-1115 |
8.65e-03 |
|
capsid maturational protease; Provisional
Pssm-ID: 223061 [Multi-domain] Cd Length: 663 Bit Score: 41.91 E-value: 8.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 983 APEEPDTAA---VRVSTPEEPAsPAAAVPTPEEPTSPAAAVPTPEEPT---SPAAAVPPPEEpTSPAAAVPTP------- 1049
Cdd:PHA03369 517 KNAGAKTAAaniEPNCSADAAA-PATKRARPETKTELEAVVRFPYQIRnmeSPAFVHSFTST-TLAAAAGQGSdtaeala 594
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2245149928 1050 ---EEPTSPAAAVPTPEEPTSPAAAVptpeeptSPAAAVPTPEePTSPAAavPTPEEPTSPAAAVPTPE 1115
Cdd:PHA03369 595 gaiETLLTQASAQPAGLSLPAPAVPV-------NASTPASTPP-PLAPQE--PPQPGTSAPSLETSLPQ 653
|
|
| PLN02550 |
PLN02550 |
threonine dehydratase |
1120-1236 |
8.93e-03 |
|
threonine dehydratase
Pssm-ID: 178165 [Multi-domain] Cd Length: 591 Bit Score: 41.83 E-value: 8.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1120 PAAAVPTPEEP-ASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASF-AAVVATLEEPTS 1197
Cdd:PLN02550 2 SSVGLPTAGSPlRSHIGSPSKPVVGSTPFSRSRIPAAVDSADETSMAPPPPPSPLPLLKVSPNSLQYpAGYLGAVPERTN 81
|
90 100 110
....*....|....*....|....*....|....*....
gi 2245149928 1198 PAASVPTPAAMVATLEEFTSPAASVPTsEEPASLAAAVS 1236
Cdd:PLN02550 82 EAENGSIPEAMEYLTNILSAKVYDVAI-ESPLQLAKKLS 119
|
|
| EF-hand_5 |
pfam13202 |
EF hand; |
3175-3193 |
8.99e-03 |
|
EF hand;
Pssm-ID: 433035 [Multi-domain] Cd Length: 25 Bit Score: 36.14 E-value: 8.99e-03
|
| PRK12373 |
PRK12373 |
NADH-quinone oxidoreductase subunit E; |
1091-1208 |
9.02e-03 |
|
NADH-quinone oxidoreductase subunit E;
Pssm-ID: 237082 [Multi-domain] Cd Length: 400 Bit Score: 41.71 E-value: 9.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTP---EESASAAVAVPTPE 1167
Cdd:PRK12373 194 LTSLTEEAGKARYNASKALAEDIGDTVKRIDGTEVPLLAPWQGDAAPVPPSEAARPKSADAETnaaLKTPATAPKAAAKN 273
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 2245149928 1168 ESASPAAAVPTPAESASFAAVVATLE-EPTSPAASV-PTPAAM 1208
Cdd:PRK12373 274 AKAPEAQPVSGTAAAEPAPKEAAKAAaAAAKPALEDkPRPLGI 316
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
2408-2787 |
9.27e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.96 E-value: 9.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2408 ETVNKAGNELLesSAGDDASSLRSRLEAMNQCWESVLQKTEER-------EQQLQSTLQQAQGFHSEIEDFLLELTRMES 2480
Cdd:TIGR00606 695 EFISDLQSKLR--LAPDKLKSTESELKKKEKRRDEMLGLAPGRqsiidlkEKEIPELRNKLQKVNRDIQRLKNDIEEQET 772
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2481 QLSASKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKgrlmLLSRDDSGSGSKTEQSVALLEQKWHVVSSKMEER 2560
Cdd:TIGR00606 773 LLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAK----LQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELN 848
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2561 KSKLEEALNLATEFQNSLQEF-INWLTLAEqslNIASPPSLILNTVlSQIEEHKVFANEVNAHRDQIIELDQTgnqlkfl 2639
Cdd:TIGR00606 849 RKLIQDQQEQIQHLKSKTNELkSEKLQIGT---NLQRRQQFEEQLV-ELSTEVQSLIREIKDAKEQDSPLETF------- 917
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2640 sqKQDVVLIKNLLVSVQSRWEKVVQRSIErgrsldDARKRAKQFHEAWKKLIDWLEDAEShlDSELEISNDPDKIKLQLS 2719
Cdd:TIGR00606 918 --LEKDQQEKEELISSKETSNKKAQDKVN------DIKEKVKNIHGYMKDIENKIQDGKD--DYLKQKETELNTVNAQLE 987
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 2720 ---KHKE-FQKTLGGKQPVYDTTIRTGRALKEKTLLpedsQKLDNFLGEVRDKWDTVCGKSVERQ--------HKLEEAL 2787
Cdd:TIGR00606 988 eceKHQEkINEDMRLMRQDIDTQKIQERWLQDNLTL----RKRENELKEVEEELKQHLKEMGQMQvlqmkqehQKLEENI 1063
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
1045-1317 |
9.35e-03 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 41.68 E-value: 9.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1045 AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP-TPEEPTSPAAAVPTPEEPASPAAA 1123
Cdd:NF033839 139 AVSKFEKDSSSSSSSGSSTKPETPQPENPEHQKPTTPAPDTKPSPQPEGKKPSVPdINQEKEKAKLAVATYMSKILDDIQ 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1124 VPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESasfAAVVATLEEPTSPAASVP 1203
Cdd:NF033839 219 KHHLQKEKHRQIVALIKELDELKKQALSEIDNVNTKVEIENTVHKIFADMDAVVTKFKK---GLTQDTPKEPGNKKPSAP 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1204 TPAAMvatleefTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVL-TPEELSSPAASVPTPE---E 1279
Cdd:NF033839 296 KPGMQ-------PSPQPEKKEVKPEPETPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQLeTPKPEVKPQPEKPKPEvkpQ 368
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 2245149928 1280 PASPAAAVSnlEEPASPAAAV------PTPEVAaiPAASVPTPE 1317
Cdd:NF033839 369 PEKPKPEVK--PQPETPKPEVkpqpekPKPEVK--PQPEKPKPE 408
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
1441-1710 |
9.37e-03 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 41.75 E-value: 9.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1441 LEHDMEEINARWNTLNKKVAQRIAQLQEA---LLHCG------KFQDALEPLLSWLADTEELIANQKPPSAEYKV----- 1506
Cdd:PRK04778 210 LEQIMEEIPELLKELQTELPDQLQELKAGyreLVEEGyhldhlDIEKEIQDLKEQIDENLALLEELDLDEAEEKNeeiqe 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1507 ------------VKAQ---IQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADRE-----KITGQLESLESRWTELLS 1566
Cdd:PRK04778 290 ridqlydilereVKARkyvEKNSDTLPDFLEHAKEQNKELKEEIDRVKQSYTLNESElesvrQLEKQLESLEKQYDEITE 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1567 KAAAR-------QKQLEDILVLAKQFHETAEPISDFLsvteKKLANSEPVGTQTAKIQQQ----IIRH-KALN-----EE 1629
Cdd:PRK04778 370 RIAEQeiayselQEELEEILKQLEEIEKEQEKLSEML----QGLRKDELEAREKLERYRNklheIKRYlEKSNlpglpED 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245149928 1630 IVNRKKNVDQAIkngQALLKQTtgEEVLL----IQEKLDGIKTryaDITVTSSKALRTLEQAR------QLATKFQSTYE 1699
Cdd:PRK04778 446 YLEMFFEVSDEI---EALAEEL--EEKPInmeaVNRLLEEATE---DVETLEEETEELVENATlteqliQYANRYRSDNE 517
|
330
....*....|.
gi 2245149928 1700 ELTGWLREVEE 1710
Cdd:PRK04778 518 EVAEALNEAER 528
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
999-1073 |
9.44e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 41.65 E-value: 9.44e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2245149928 999 EPASPAAAVPTPEEPTSPAAAVPTPEeptspAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1073
Cdd:PRK14965 378 ERGAPAPPSAAWGAPTPAAPAAPPPA-----AAPPVPPAAPARPAAARPAPAPAPPAAAAPPARSADPAAAASAG 447
|
|
| EFh_PEF_ALG-2 |
cd16183 |
EF-hand, calcium binding motif, found in apoptosis-linked gene 2 protein (ALG-2) and similar ... |
3173-3231 |
9.62e-03 |
|
EF-hand, calcium binding motif, found in apoptosis-linked gene 2 protein (ALG-2) and similar proteins; ALG-2, also termed programmed cell death protein 6 (PDCD6), or probable calcium-binding protein ALG-2, is one of the prototypic members of the penta EF-hand protein family. It is a widely expressed calcium-binding modulator protein associated with cell proliferation and death, as well as cell survival. ALG-2 acts as a pro-apoptotic factor participating in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death, and also serves as a useful molecular marker for the prognosis of cancers. Moreover, ALG-2 functions as a calcium ion sensor at endoplasmic reticulum (ER) exit sites, and modulates ER-stress-stimulated cell death and neuronal apoptosis during organ formation. Furthermore, ALG-2 can mediate the pro-apoptotic activity of cisplatin or tumor necrosis factor alpha (TNFalpha) through the down-regulation of nuclear factor-kappaB (NF-kappaB) expression. It also inhibits angiogenesis through PI3K/mTOR/p70S6K pathway by interacting of vascular endothelial growth factor receptor-2 (VEGFR-2). In addition, nuclear ALG-2 may participate in the post-transcriptional regulation of Inositol Trisphosphate Receptor Type 1 (IP3R1) pre-mRNA at least in part by interacting with CHERP (Ca2+ homeostasis endoplasmic reticulum protein) calcium-dependently. ALG-2 contains five serially repeated EF-hand motifs and interacts with various proteins, including ALG-2-interacting protein X (Alix), Fas, annexin XI, death-associated protein kinase 1 (DAPk1), Tumor susceptibility gene 101 (TSG101), Sec31A, phospholipid scramblase 3 (PLSCR3), the P-body component PATL1, and endosomal sorting complex required for transport (ESCRT)-III-related protein IST1, in a calcium-dependent manner. It forms a homodimer in the cell or a heterodimer with its closest paralog peflin. Among the PEF proteins, ALG-2 can bind three Ca2+ ions through its EF1, EF3, and EF5 hands, where it is unique in that its EF5 hand binds Ca2+ ion in a canonical coordination.
Pssm-ID: 320058 [Multi-domain] Cd Length: 165 Bit Score: 39.55 E-value: 9.62e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2245149928 3173 VMDFFRRIDKDQDGKIT----RQEFIDGILASKFPTTKLEMTAvadIFDRDGDGYIDYYEFVA 3231
Cdd:cd16183 2 LWNVFQRVDKDRSGQISatelQQALSNGTWTPFNPETVRLMIG---MFDRDNSGTINFQEFAA 61
|
|
| |
