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Conserved domains on  [gi|2161398609|ref|NP_989563|]
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protein HIRA [Gallus gallus]

Protein Classification

WD40 and Hira domain-containing protein( domain architecture ID 11456814)

WD40 and Hira domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Hira pfam07569
TUP1-like enhancer of split; The Hira proteins are found in a range of eukaryotes and are ...
 770-968 1.10e-67

TUP1-like enhancer of split; The Hira proteins are found in a range of eukaryotes and are implicated in the assembly of repressive chromatin. These proteins also contain pfam00400.


:

Pssm-ID: 462211  Cd Length: 221  Bit Score: 225.96  E-value: 1.10e-67
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  770 GRRLLPPIILNTPISTLHCTGSYIMTLTTAATLSVWDVHKQTVIVRDESLQTILSGS---------DTTVSQILLTQHGI 840
Cdd:pfam07569    1 GRRLLPPIVLGSPASFLECSGSYLLAVTSVGLLYVWDIKKQKALLPPVSLAPLLDSSsrysdkltrAPTITSASLTSNGV 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  841 PVMSMSDGKAYCFNPSLSTWNLVSDKQDSLA-QCADFRSSLPSQEAMLCSGPLAVIQGRTSN--SGRQAARLFSMPHLV- 916
Cdd:pfam07569   81 PIVTLSNGDGYLYDKSLETWLRISDSWWALGsQYWDSTGSSRSSSQSSAAGILSFLERKTNEelLRKGRGRLLQRLAKTl 160

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2161398609  917 ---------QQETTLAYLENQIAAALMLQSSHEYRHWLLIYARYLVNEGFEYRLRELCKDL 968
Cdd:pfam07569  161 lmkegfenfETVVTLAHLENRLAAALLLGSPDEYRHWLLMYAKRLAEEGLKGRLRELCKEL 221
WD40 COG2319
WD40 repeat [General function prediction only];
3-352 7.38e-44

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 164.70  E-value: 7.38e-44
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609    3 LLKPTWVNHNGkPIFSVDIHPDGTKFATGGqgqDSGKVVIWNMAPvlkeedekneniPKMLCQMDNHLACVNCVRWSNNG 82
Cdd:COG2319    111 LLLRTLTGHTG-AVRSVAFSPDGKTLASGS---ADGTVRLWDLAT------------GKLLRTLTGHSGAVTSVAFSPDG 174

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609   83 VYLASGGDDKLIMVWkraayigpstvfgssskltNVEQWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNaVK 162
Cdd:COG2319    175 KLLASGSDDGTVRLW-------------------DLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWD-LA 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  163 FPEILATLKGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTMDWQLETSITkpfdecGGTTHVLRLSWSPDGHYLVSAha 242
Cdd:COG2319    235 TGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLT------GHSGGVNSVAFSPDGKLLASG-- 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  243 mnNSGPTAQIIERDGWKTNMDFVGHRKAVTVVKFNPkifkkkqkNGSSTksscpycccAVGSKDRSLSVWLTCLKRPLVV 322
Cdd:COG2319    307 --SDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSP--------DGKTL---------ASGSDDGTVRLWDLATGELLRT 367

                          330       340       350
                   ....*....|....*....|....*....|
gi 2161398609  323 IHElFDKSIMDISWTLNGLGILVCSMDGSV 352
Cdd:COG2319    368 LTG-HTGAVTSVAFSPDGRTLASGSADGTV 396
 
Name Accession Description Interval E-value
Hira pfam07569
TUP1-like enhancer of split; The Hira proteins are found in a range of eukaryotes and are ...
 770-968 1.10e-67

TUP1-like enhancer of split; The Hira proteins are found in a range of eukaryotes and are implicated in the assembly of repressive chromatin. These proteins also contain pfam00400.


Pssm-ID: 462211  Cd Length: 221  Bit Score: 225.96  E-value: 1.10e-67
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  770 GRRLLPPIILNTPISTLHCTGSYIMTLTTAATLSVWDVHKQTVIVRDESLQTILSGS---------DTTVSQILLTQHGI 840
Cdd:pfam07569    1 GRRLLPPIVLGSPASFLECSGSYLLAVTSVGLLYVWDIKKQKALLPPVSLAPLLDSSsrysdkltrAPTITSASLTSNGV 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  841 PVMSMSDGKAYCFNPSLSTWNLVSDKQDSLA-QCADFRSSLPSQEAMLCSGPLAVIQGRTSN--SGRQAARLFSMPHLV- 916
Cdd:pfam07569   81 PIVTLSNGDGYLYDKSLETWLRISDSWWALGsQYWDSTGSSRSSSQSSAAGILSFLERKTNEelLRKGRGRLLQRLAKTl 160

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2161398609  917 ---------QQETTLAYLENQIAAALMLQSSHEYRHWLLIYARYLVNEGFEYRLRELCKDL 968
Cdd:pfam07569  161 lmkegfenfETVVTLAHLENRLAAALLLGSPDEYRHWLLMYAKRLAEEGLKGRLRELCKEL 221
WD40 COG2319
WD40 repeat [General function prediction only];
3-352 7.38e-44

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 164.70  E-value: 7.38e-44
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609    3 LLKPTWVNHNGkPIFSVDIHPDGTKFATGGqgqDSGKVVIWNMAPvlkeedekneniPKMLCQMDNHLACVNCVRWSNNG 82
Cdd:COG2319    111 LLLRTLTGHTG-AVRSVAFSPDGKTLASGS---ADGTVRLWDLAT------------GKLLRTLTGHSGAVTSVAFSPDG 174

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609   83 VYLASGGDDKLIMVWkraayigpstvfgssskltNVEQWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNaVK 162
Cdd:COG2319    175 KLLASGSDDGTVRLW-------------------DLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWD-LA 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  163 FPEILATLKGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTMDWQLETSITkpfdecGGTTHVLRLSWSPDGHYLVSAha 242
Cdd:COG2319    235 TGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLT------GHSGGVNSVAFSPDGKLLASG-- 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  243 mnNSGPTAQIIERDGWKTNMDFVGHRKAVTVVKFNPkifkkkqkNGSSTksscpycccAVGSKDRSLSVWLTCLKRPLVV 322
Cdd:COG2319    307 --SDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSP--------DGKTL---------ASGSDDGTVRLWDLATGELLRT 367

                          330       340       350
                   ....*....|....*....|....*....|
gi 2161398609  323 IHElFDKSIMDISWTLNGLGILVCSMDGSV 352
Cdd:COG2319    368 LTG-HTGAVTSVAFSPDGRTLASGSADGTV 396
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 7-352 1.53e-41

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 154.42  E-value: 1.53e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609    7 TWVNHNGkPIFSVDIHPDGTKFATGGQgqdSGKVVIWNMAPVLKEEDEKNenipkmlcqmdnHLACVNCVRWSNNGVYLA 86
Cdd:cd00200      4 TLKGHTG-GVTCVAFSPDGKLLATGSG---DGTIKVWDLETGELLRTLKG------------HTGPVRDVAASADGTYLA 67

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609   87 SGGDDKLIMVWkraayigpstvfgssskltNVEQWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFpEI 166
Cdd:cd00200     68 SGSSDKTIRLW-------------------DLETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETG-KC 127

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  167 LATLKGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTMDWQLETSItkpfdecggTTH---VLRLSWSPDGHYLVSAham 243
Cdd:cd00200    128 LTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATL---------TGHtgeVNSVAFSPDGEKLLSS--- 195

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  244 nNSGPTAQIIERDGWKTNMDFVGHRKAVTVVKFNP--KIFkkkqkngsstksscpycccAVGSKDRSLSVWLTCLKRPLV 321
Cdd:cd00200    196 -SSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPdgYLL-------------------ASGSEDGTIRVWDLRTGECVQ 255

                          330       340       350
                   ....*....|....*....|....*....|.
gi 2161398609  322 VIHElFDKSIMDISWTLNGLGILVCSMDGSV 352
Cdd:cd00200    256 TLSG-HTNSVTSLAWSPDGKRLASGSADGTI 285
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 120-159 2.14e-09

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 53.86  E-value: 2.14e-09
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|
gi 2161398609   120 QWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWN 159
Cdd:smart00320    1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
121-159 3.25e-09

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 53.12  E-value: 3.25e-09
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 2161398609  121 WRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWN 159
Cdd:pfam00400    1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
PTZ00420 PTZ00420
coronin; Provisional
 127-201 1.67e-05

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 48.79  E-value: 1.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  127 LRSHSGDVMDVAWSP-HDAWLASCSVDNTVVIW---------NAVKFPeiLATLKGHSGLVKGLTWDPVGKYI-ASQADD 195
Cdd:PTZ00420    70 LKGHTSSILDLQFNPcFSEILASGSEDLTIRVWeiphndesvKEIKDP--QCILKGHKKKISIIDWNPMNYYImCSSGFD 147


                   ....*.
gi 2161398609  196 RSLKVW 201
Cdd:PTZ00420   148 SFVNIW 153
 
Name Accession Description Interval E-value
Hira pfam07569
TUP1-like enhancer of split; The Hira proteins are found in a range of eukaryotes and are ...
 770-968 1.10e-67

TUP1-like enhancer of split; The Hira proteins are found in a range of eukaryotes and are implicated in the assembly of repressive chromatin. These proteins also contain pfam00400.


Pssm-ID: 462211  Cd Length: 221  Bit Score: 225.96  E-value: 1.10e-67
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  770 GRRLLPPIILNTPISTLHCTGSYIMTLTTAATLSVWDVHKQTVIVRDESLQTILSGS---------DTTVSQILLTQHGI 840
Cdd:pfam07569    1 GRRLLPPIVLGSPASFLECSGSYLLAVTSVGLLYVWDIKKQKALLPPVSLAPLLDSSsrysdkltrAPTITSASLTSNGV 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  841 PVMSMSDGKAYCFNPSLSTWNLVSDKQDSLA-QCADFRSSLPSQEAMLCSGPLAVIQGRTSN--SGRQAARLFSMPHLV- 916
Cdd:pfam07569   81 PIVTLSNGDGYLYDKSLETWLRISDSWWALGsQYWDSTGSSRSSSQSSAAGILSFLERKTNEelLRKGRGRLLQRLAKTl 160

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2161398609  917 ---------QQETTLAYLENQIAAALMLQSSHEYRHWLLIYARYLVNEGFEYRLRELCKDL 968
Cdd:pfam07569  161 lmkegfenfETVVTLAHLENRLAAALLLGSPDEYRHWLLMYAKRLAEEGLKGRLRELCKEL 221
WD40 COG2319
WD40 repeat [General function prediction only];
3-352 7.38e-44

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 164.70  E-value: 7.38e-44
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609    3 LLKPTWVNHNGkPIFSVDIHPDGTKFATGGqgqDSGKVVIWNMAPvlkeedekneniPKMLCQMDNHLACVNCVRWSNNG 82
Cdd:COG2319    111 LLLRTLTGHTG-AVRSVAFSPDGKTLASGS---ADGTVRLWDLAT------------GKLLRTLTGHSGAVTSVAFSPDG 174

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609   83 VYLASGGDDKLIMVWkraayigpstvfgssskltNVEQWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNaVK 162
Cdd:COG2319    175 KLLASGSDDGTVRLW-------------------DLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWD-LA 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  163 FPEILATLKGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTMDWQLETSITkpfdecGGTTHVLRLSWSPDGHYLVSAha 242
Cdd:COG2319    235 TGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLT------GHSGGVNSVAFSPDGKLLASG-- 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  243 mnNSGPTAQIIERDGWKTNMDFVGHRKAVTVVKFNPkifkkkqkNGSSTksscpycccAVGSKDRSLSVWLTCLKRPLVV 322
Cdd:COG2319    307 --SDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSP--------DGKTL---------ASGSDDGTVRLWDLATGELLRT 367

                          330       340       350
                   ....*....|....*....|....*....|
gi 2161398609  323 IHElFDKSIMDISWTLNGLGILVCSMDGSV 352
Cdd:COG2319    368 LTG-HTGAVTSVAFSPDGRTLASGSADGTV 396
WD40 COG2319
WD40 repeat [General function prediction only];
2-312 3.66e-42

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 159.69  E-value: 3.66e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609    2 KLLKpTWVNHNGkPIFSVDIHPDGTKFATGGqgqDSGKVVIWNMAPvlkeedekneniPKMLCQMDNHLACVNCVRWSNN 81
Cdd:COG2319    153 KLLR-TLTGHSG-AVTSVAFSPDGKLLASGS---DDGTVRLWDLAT------------GKLLRTLTGHTGAVRSVAFSPD 215

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609   82 GVYLASGGDDKLIMVWkraayigpstvfgssskltNVEQWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNaV 161
Cdd:COG2319    216 GKLLASGSADGTVRLW-------------------DLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWD-L 275

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  162 KFPEILATLKGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTMDWQLETSITkpfdecGGTTHVLRLSWSPDGHYLVSAH 241
Cdd:COG2319    276 ATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLT------GHTGAVRSVAFSPDGKTLASGS 349

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2161398609  242 AMNnsgpTAQIIERDGWKTNMDFVGHRKAVTVVKFNPkifkkkqkNGSSTksscpycccAVGSKDRSLSVW 312
Cdd:COG2319    350 DDG----TVRLWDLATGELLRTLTGHTGAVTSVAFSP--------DGRTL---------ASGSADGTVRLW 399
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 7-352 1.53e-41

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 154.42  E-value: 1.53e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609    7 TWVNHNGkPIFSVDIHPDGTKFATGGQgqdSGKVVIWNMAPVLKEEDEKNenipkmlcqmdnHLACVNCVRWSNNGVYLA 86
Cdd:cd00200      4 TLKGHTG-GVTCVAFSPDGKLLATGSG---DGTIKVWDLETGELLRTLKG------------HTGPVRDVAASADGTYLA 67

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609   87 SGGDDKLIMVWkraayigpstvfgssskltNVEQWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFpEI 166
Cdd:cd00200     68 SGSSDKTIRLW-------------------DLETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETG-KC 127

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  167 LATLKGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTMDWQLETSItkpfdecggTTH---VLRLSWSPDGHYLVSAham 243
Cdd:cd00200    128 LTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATL---------TGHtgeVNSVAFSPDGEKLLSS--- 195

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  244 nNSGPTAQIIERDGWKTNMDFVGHRKAVTVVKFNP--KIFkkkqkngsstksscpycccAVGSKDRSLSVWLTCLKRPLV 321
Cdd:cd00200    196 -SSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPdgYLL-------------------ASGSEDGTIRVWDLRTGECVQ 255

                          330       340       350
                   ....*....|....*....|....*....|.
gi 2161398609  322 VIHElFDKSIMDISWTLNGLGILVCSMDGSV 352
Cdd:cd00200    256 TLSG-HTNSVTSLAWSPDGKRLASGSADGTI 285
WD40 COG2319
WD40 repeat [General function prediction only];
15-367 5.33e-38

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 147.37  E-value: 5.33e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609   15 PIFSVDIHPDGTKFATGGqgqDSGKVVIWNMAPvlkeedekneniPKMLCQMDNHLACVNCVRWSNNGVYLASGGDDKLI 94
Cdd:COG2319     80 AVLSVAFSPDGRLLASAS---ADGTVRLWDLAT------------GLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTV 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609   95 MVWkraayigpstvfgssskltNVEQWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKfPEILATLKGHS 174
Cdd:COG2319    145 RLW-------------------DLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLAT-GKLLRTLTGHT 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  175 GLVKGLTWDPVGKYIASQADDRSLKVWRTMDWQLETSITkpfdecGGTTHVLRLSWSPDGHYLVSAHAmnnsGPTAQIIE 254
Cdd:COG2319    205 GAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLT------GHSGSVRSVAFSPDGRLLASGSA----DGTVRLWD 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  255 RDGWKTNMDFVGHRKAVTVVKFNPkifkkkqkNGSStksscpyccCAVGSKDRSLSVWlTCLKRPLVVIHELFDKSIMDI 334
Cdd:COG2319    275 LATGELLRTLTGHSGGVNSVAFSP--------DGKL---------LASGSDDGTVRLW-DLATGKLLRTLTGHTGAVRSV 336

                          330       340       350
                   ....*....|....*....|....*....|...
gi 2161398609  335 SWTLNGLGILVCSMDGSVAFLDFSQDELGDPLS 367
Cdd:COG2319    337 AFSPDGKTLASGSDDGTVRLWDLATGELLRTLT 369
WD40 COG2319
WD40 repeat [General function prediction only];
69-367 5.54e-34

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 135.42  E-value: 5.54e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609   69 HLACVNCVRWSNNGVYLASGGDDKLIMVWkraayigpstvfgssskltNVEQWRCVSILRSHSGDVMDVAWSPHDAWLAS 148
Cdd:COG2319     77 HTAAVLSVAFSPDGRLLASASADGTVRLW-------------------DLATGLLLRTLTGHTGAVRSVAFSPDGKTLAS 137

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  149 CSVDNTVVIWNAVKfPEILATLKGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTMDWQLETSITkpfdecGGTTHVLRL 228
Cdd:COG2319    138 GSADGTVRLWDLAT-GKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLT------GHTGAVRSV 210

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  229 SWSPDGHYLVSAHAmnnsGPTAQIIERDGWKTNMDFVGHRKAVTVVKFNPkifkkkqkNGSStksscpyccCAVGSKDRS 308
Cdd:COG2319    211 AFSPDGKLLASGSA----DGTVRLWDLATGKLLRTLTGHSGSVRSVAFSP--------DGRL---------LASGSADGT 269

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2161398609  309 LSVWLTCLKRPLVVIHELFDkSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLS 367
Cdd:COG2319    270 VRLWDLATGELLRTLTGHSG-GVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLT 327
WD40 COG2319
WD40 repeat [General function prediction only];
10-203 5.15e-33

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 132.73  E-value: 5.15e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609   10 NHNGKPIFSVDIHPDGTKFATGGqgqDSGKVVIWNMAPvlkeedekneniPKMLCQMDNHLACVNCVRWSNNGVYLASGG 89
Cdd:COG2319    243 TGHSGSVRSVAFSPDGRLLASGS---ADGTVRLWDLAT------------GELLRTLTGHSGGVNSVAFSPDGKLLASGS 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609   90 DDKLIMVWkraayigpstvfgssskltNVEQWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNaVKFPEILAT 169
Cdd:COG2319    308 DDGTVRLW-------------------DLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWD-LATGELLRT 367

                          170       180       190
                   ....*....|....*....|....*....|....
gi 2161398609  170 LKGHSGLVKGLTWDPVGKYIASQADDRSLKVWRT 203
Cdd:COG2319    368 LTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDL 401
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 7-202 4.44e-28

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 115.12  E-value: 4.44e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609    7 TWVNHNgKPIFSVDIHPDGTKFATGGqgqDSGKVVIWNMapvlkeedEKNENIPKMLCqmdnHLACVNCVRWSNNGVYLA 86
Cdd:cd00200     88 TLTGHT-SYVSSVAFSPDGRILSSSS---RDKTIKVWDV--------ETGKCLTTLRG----HTDWVNSVAFSPDGTFVA 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609   87 SGGDDKLIMVW------------------KRAAYIGPSTVFGSSS-----KLTNVEQWRCVSILRSHSGDVMDVAWSPHD 143
Cdd:cd00200    152 SSSQDGTIKLWdlrtgkcvatltghtgevNSVAFSPDGEKLLSSSsdgtiKLWDLSTGKCLGTLRGHENGVNSVAFSPDG 231

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2161398609  144 AWLASCSVDNTVVIWNAVKFpEILATLKGHSGLVKGLTWDPVGKYIASQADDRSLKVWR 202
Cdd:cd00200    232 YLLASGSEDGTIRVWDLRTG-ECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 123-372 9.73e-26

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 108.19  E-value: 9.73e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  123 CVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNaVKFPEILATLKGHSGLVKGLTWDPVGKYIASQADDRSLKVWR 202
Cdd:cd00200      1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWD-LETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWD 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  203 TMDWQLETSITkpfdecGGTTHVLRLSWSPDGHYLVSAHamnnsgptaqiieRDG----WKTN-----MDFVGHRKAVTV 273
Cdd:cd00200     80 LETGECVRTLT------GHTSYVSSVAFSPDGRILSSSS-------------RDKtikvWDVEtgkclTTLRGHTDWVNS 140

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  274 VKFNPkifkkkqkngSSTKSSCpycccavGSKDRSLSVW-LTCLKrpLVVIHELFDKSIMDISWTLNGLGILVCSMDGSV 352
Cdd:cd00200    141 VAFSP----------DGTFVAS-------SSQDGTIKLWdLRTGK--CVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTI 201

                          250       260
                   ....*....|....*....|
gi 2161398609  353 AFLDFSQDELGDPLSEEEKS 372
Cdd:cd00200    202 KLWDLSTGKCLGTLRGHENG 221
WD40 COG2319
WD40 repeat [General function prediction only];
96-367 2.00e-25

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 110.00  E-value: 2.00e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609   96 VWKRAAYIGPSTVFGSSSKLTNVEQWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNaVKFPEILATLKGHSG 175
Cdd:COG2319     43 AASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWD-LATGLLLRTLTGHTG 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  176 LVKGLTWDPVGKYIASQADDRSLKVWRTMDWQLETSITkpfdecGGTTHVLRLSWSPDGHYLVSAHamnnSGPTAQIIER 255
Cdd:COG2319    122 AVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLT------GHSGAVTSVAFSPDGKLLASGS----DDGTVRLWDL 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  256 DGWKTNMDFVGHRKAVTVVKFNP--KIFkkkqkngsstksscpycccAVGSKDRSLSVW-LTclKRPLVVIHELFDKSIM 332
Cdd:COG2319    192 ATGKLLRTLTGHTGAVRSVAFSPdgKLL-------------------ASGSADGTVRLWdLA--TGKLLRTLTGHSGSVR 250

                          250       260       270
                   ....*....|....*....|....*....|....*
gi 2161398609  333 DISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLS 367
Cdd:COG2319    251 SVAFSPDGRLLASGSADGTVRLWDLATGELLRTLT 285
WD40 COG2319
WD40 repeat [General function prediction only];
115-367 5.51e-16

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 81.50  E-value: 5.51e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  115 LTNVEQWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKfPEILATLKGHSGLVKGLTWDPVGKYIASQAD 194
Cdd:COG2319     20 LLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAA-GALLATLLGHTAAVLSVAFSPDGRLLASASA 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  195 DRSLKVWRTMDWQLETSITkpfdecGGTTHVLRLSWSPDGHYLVSAHAmnnsGPTAQIIERDGWKTNMDFVGHRKAVTVV 274
Cdd:COG2319     99 DGTVRLWDLATGLLLRTLT------GHTGAVRSVAFSPDGKTLASGSA----DGTVRLWDLATGKLLRTLTGHSGAVTSV 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  275 KFNPkifkkkqkNGSSTksscpycccAVGSKDRSLSVWLTCLKRPLVVI--HelfDKSIMDISWTLNGLGILVCSMDGSV 352
Cdd:COG2319    169 AFSP--------DGKLL---------ASGSDDGTVRLWDLATGKLLRTLtgH---TGAVRSVAFSPDGKLLASGSADGTV 228

                          250
                   ....*....|....*
gi 2161398609  353 AFLDFSQDELGDPLS 367
Cdd:COG2319    229 RLWDLATGKLLRTLT 243
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 120-159 2.14e-09

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 53.86  E-value: 2.14e-09
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|
gi 2161398609   120 QWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWN 159
Cdd:smart00320    1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
121-159 3.25e-09

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 53.12  E-value: 3.25e-09
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 2161398609  121 WRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWN 159
Cdd:pfam00400    1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 COG2319
WD40 repeat [General function prediction only];
7-100 3.30e-07

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 53.76  E-value: 3.30e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609    7 TWVNHNGkPIFSVDIHPDGTKFATGGqgqDSGKVVIWNMAPvlkeedekneniPKMLCQMDNHLACVNCVRWSNNGVYLA 86
Cdd:COG2319    325 TLTGHTG-AVRSVAFSPDGKTLASGS---DDGTVRLWDLAT------------GELLRTLTGHTGAVTSVAFSPDGRTLA 388

                           90
                   ....*....|....
gi 2161398609   87 SGGDDKLIMVWKRA 100
Cdd:COG2319    389 SGSADGTVRLWDLA 402
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 165-201 3.64e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 44.61  E-value: 3.64e-06
                            10        20        30
                    ....*....|....*....|....*....|....*..
gi 2161398609   165 EILATLKGHSGLVKGLTWDPVGKYIASQADDRSLKVW 201
Cdd:smart00320    3 ELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLW 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 61-98 4.79e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 44.23  E-value: 4.79e-06
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 2161398609    61 KMLCQMDNHLACVNCVRWSNNGVYLASGGDDKLIMVWK 98
Cdd:smart00320    3 ELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
PTZ00420 PTZ00420
coronin; Provisional
 127-201 1.67e-05

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 48.79  E-value: 1.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  127 LRSHSGDVMDVAWSP-HDAWLASCSVDNTVVIW---------NAVKFPeiLATLKGHSGLVKGLTWDPVGKYI-ASQADD 195
Cdd:PTZ00420    70 LKGHTSSILDLQFNPcFSEILASGSEDLTIRVWeiphndesvKEIKDP--QCILKGHKKKISIIDWNPMNYYImCSSGFD 147


                   ....*.
gi 2161398609  196 RSLKVW 201
Cdd:PTZ00420   148 SFVNIW 153
WD40 pfam00400
WD domain, G-beta repeat;
61-97 2.06e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 42.33  E-value: 2.06e-05
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 2161398609   61 KMLCQMDNHLACVNCVRWSNNGVYLASGGDDKLIMVW 97
Cdd:pfam00400    2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVW 38
WD40 pfam00400
WD domain, G-beta repeat;
165-201 2.65e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 41.95  E-value: 2.65e-05
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 2161398609  165 EILATLKGHSGLVKGLTWDPVGKYIASQADDRSLKVW 201
Cdd:pfam00400    2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVW 38
COG4946 COG4946
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ...
 129-245 7.31e-05

Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];


Pssm-ID: 443973 [Multi-domain]  Cd Length: 1072  Bit Score: 46.96  E-value: 7.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161398609  129 SHSGDVMD--VAWSPHDAWLASCS-VDNTVVIW----NAVKFPEILAtlKGHSGLVKGLTWDPVGKYIASQADDRSLKVw 201
Cdd:COG4946    338 TNTPGVRErlPAWSPDGKSIAYFSdASGEYELYiapaDGSGEPKQLT--LGDLGRVFNPVWSPDGKKIAFTDNRGRLWV- 414

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 2161398609  202 rtMDwqLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNN 245
Cdd:COG4946    415 --VD--LASGKVRKVDTDGYGDGISDLAWSPDSKWLAYSKPGPN 454
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 7-44 6.59e-03

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 35.37  E-value: 6.59e-03
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 2161398609     7 TWVNHNGkPIFSVDIHPDGTKFATGGqgqDSGKVVIWN 44
Cdd:smart00320    7 TLKGHTG-PVTSVAFSPDGKYLASGS---DDGTIKLWD 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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