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Conserved domains on  [gi|31983687|ref|NP_858241|]
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IS600 ORF1 (plasmid) [Shigella flexneri 2a str. 301]

Protein Classification

transposase( domain architecture ID 11459289)

transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism; similar to Escherichia coli IS150 protein InsAB

CATH:  1.10.10.10
Gene Ontology:  GO:0006313|GO:0003677|GO:0004803
PubMed:  20885819

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
1-91 1.27e-20

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


:

Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 78.43  E-value: 1.27e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31983687   1 MSRKTQRYSKEFKAEAVRTVLENQLSISEGASRLSLPEGTLGQWVTAARKG--LGTPGSRTVAELESEILQLRKALNEAR 78
Cdd:COG2963   1 MSKKRRRYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYREGglGGFPGDGRTTPEQAEIRRLRKELRRLE 80

                        90
                ....*....|...
gi 31983687  79 LERDILKKATAYF 91
Cdd:COG2963  81 MENDILKKAAALL 93
 
Name Accession Description Interval E-value
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
1-91 1.27e-20

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 78.43  E-value: 1.27e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31983687   1 MSRKTQRYSKEFKAEAVRTVLENQLSISEGASRLSLPEGTLGQWVTAARKG--LGTPGSRTVAELESEILQLRKALNEAR 78
Cdd:COG2963   1 MSKKRRRYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYREGglGGFPGDGRTTPEQAEIRRLRKELRRLE 80

                        90
                ....*....|...
gi 31983687  79 LERDILKKATAYF 91
Cdd:COG2963  81 MENDILKKAAALL 93
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 3-75 4.17e-16

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 66.61  E-value: 4.17e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 31983687     3 RKTQRYSKEFKAEAVRTVLENQLSISEGASRLSLPEGTLGQWVTAARKGLG-TPGSRTVAELESEILQLRKALN 75
Cdd:pfam01527   2 KKRRRFSEEFKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQYEGGMGaSPARPRLTALEEENRRLKRELA 75
transpos_IS3 NF033516
IS3 family transposase;
11-87 1.19e-14

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 67.59  E-value: 1.19e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31983687   11 EFKAEAVRTVLENQLSISEGASRLSLPEGTLGQWVTAARKG----LGTPGSRTVAELESEILQLRKALNEARLERDILKK 86
Cdd:NF033516   1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYRGGgeaaDAGRLKELLTPEEEENRRLKRELAELRLENEILKK 80


                 .
gi 31983687   87 A 87
Cdd:NF033516  81 A 81
 
Name Accession Description Interval E-value
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
1-91 1.27e-20

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 78.43  E-value: 1.27e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31983687   1 MSRKTQRYSKEFKAEAVRTVLENQLSISEGASRLSLPEGTLGQWVTAARKG--LGTPGSRTVAELESEILQLRKALNEAR 78
Cdd:COG2963   1 MSKKRRRYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYREGglGGFPGDGRTTPEQAEIRRLRKELRRLE 80

                        90
                ....*....|...
gi 31983687  79 LERDILKKATAYF 91
Cdd:COG2963  81 MENDILKKAAALL 93
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 3-75 4.17e-16

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 66.61  E-value: 4.17e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 31983687     3 RKTQRYSKEFKAEAVRTVLENQLSISEGASRLSLPEGTLGQWVTAARKGLG-TPGSRTVAELESEILQLRKALN 75
Cdd:pfam01527   2 KKRRRFSEEFKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQYEGGMGaSPARPRLTALEEENRRLKRELA 75
transpos_IS3 NF033516
IS3 family transposase;
11-87 1.19e-14

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 67.59  E-value: 1.19e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31983687   11 EFKAEAVRTVLENQLSISEGASRLSLPEGTLGQWVTAARKG----LGTPGSRTVAELESEILQLRKALNEARLERDILKK 86
Cdd:NF033516   1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYRGGgeaaDAGRLKELLTPEEEENRRLKRELAELRLENEILKK 80


                 .
gi 31983687   87 A 87
Cdd:NF033516  81 A 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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