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Conserved domains on  [gi|30684050|ref|NP_850594|]
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PYK10-binding protein 1 [Arabidopsis thaliana]

Protein Classification

jacalin family lectin; zinc metalloproteinase family protein( domain architecture ID 10477402)

jacalin family lectin is a sugar-binding protein containing a jacalin domain| zinc metalloproteinase family protein contains an HEXXH motif characteristic of metallopeptidases; contains a Jacalin-like lectin domain that may bind mono- or oligosaccharides

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 163-295 5.14e-63

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


:

Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 195.19  E-value: 5.14e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050   163 GTVWDDGAYVGVKKVYVGQAQDGISAVKFVYDKSPEEVTGEEHGKSTLLGFEEFVLDYPSEYITAVDGTYDKIFGSDGSV 242
Cdd:pfam01419   1 GASWDDGVYDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDYPDEYITSVEGTYDKVFGSDSEV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 30684050   243 ITMLRFKTNKQ-TSPPFGLEAGTVFELKEEGHKIVGFHGRADVLLHKIGVHVRP 295
Cdd:pfam01419  81 ITSLTFKTNKGrTSPFFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYFAP 134
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 14-141 6.36e-48

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


:

Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 156.67  E-value: 6.36e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050    14 NLWDDGsTHDAVTKIQLAAGIDGIQYVQFDYVKNGQPEQAPLRGTKGRvLPADPFVINHPDEHLVSVEGWYSP-----EG 88
Cdd:pfam01419   2 ASWDDG-VYDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGL-LGPEEFEIDYPDEYITSVEGTYDKvfgsdSE 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 30684050    89 IIQGIKFISNK-KTSDVIGSDEGTHFTLQVKDKKIIGFHGSAGGNLNSLGAYFA 141
Cdd:pfam01419  80 VITSLTFKTNKgRTSPFFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYFA 133
 
Name Accession Description Interval E-value
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 163-295 5.14e-63

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 195.19  E-value: 5.14e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050   163 GTVWDDGAYVGVKKVYVGQAQDGISAVKFVYDKSPEEVTGEEHGKSTLLGFEEFVLDYPSEYITAVDGTYDKIFGSDGSV 242
Cdd:pfam01419   1 GASWDDGVYDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDYPDEYITSVEGTYDKVFGSDSEV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 30684050   243 ITMLRFKTNKQ-TSPPFGLEAGTVFELKEEGHKIVGFHGRADVLLHKIGVHVRP 295
Cdd:pfam01419  81 ITSLTFKTNKGrTSPFFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYFAP 134
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 163-294 4.14e-50

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 161.97  E-value: 4.14e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050 163 GTVWDDGAYV-GVKKVYVGQAQDGISAVKFVYDKSPEEVTGEEHGKSTLlGFEEFVLDYPSEYITAVDGTYDKIFGSDgs 241
Cdd:cd09612   1 GSAWDDGVFPdGLRKITVRSGENGIDSIKFEYDKDGQHVVGPWHGGGGG-TPEEIVLDYPDEYITSVSGTYGPVSGSN-- 77

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|...
gi 30684050 242 VITMLRFKTNKQTSPPFGLEAGTVFELKEEGHKIVGFHGRADVLLHKIGVHVR 294
Cdd:cd09612  78 VITSLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYVS 130
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 163-295 2.34e-48

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 157.39  E-value: 2.34e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050    163 GTVWDDGAYVGVKKVYVGQAQDGISAVKFVYDKSpEEVTGEEHGKSTLLGFeeFVLDYPSEYITAVDGTYDKIfgsdgSV 242
Cdd:smart00915   1 GTEWDDGAFDGVRKIYVGQGGEGIKSIQFDYDKG-GKVWGDEHGGKGGTGE--EILLYPGEYITSVEGTYDKS-----GV 72

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 30684050    243 ITMLRFKTNK-QTSPPFGLEAGTVFELK-EEGHKIVGFHGR-ADVLLHKIGVHVRP 295
Cdd:smart00915  73 ITSLTFKTNKgRTSPFGGYEGGTKFVLEsKEGKKIVGFHGRsSGDGLDSLGAYFSP 128
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 14-141 6.36e-48

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 156.67  E-value: 6.36e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050    14 NLWDDGsTHDAVTKIQLAAGIDGIQYVQFDYVKNGQPEQAPLRGTKGRvLPADPFVINHPDEHLVSVEGWYSP-----EG 88
Cdd:pfam01419   2 ASWDDG-VYDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGL-LGPEEFEIDYPDEYITSVEGTYDKvfgsdSE 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 30684050    89 IIQGIKFISNK-KTSDVIGSDEGTHFTLQVKDKKIIGFHGSAGGNLNSLGAYFA 141
Cdd:pfam01419  80 VITSLTFKTNKgRTSPFFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYFA 133
PLN02193 PLN02193
nitrile-specifier protein
 152-293 6.21e-40

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 145.10  E-value: 6.21e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050  152 AKQLTAFGSDDGTVWDDGAYVGVKKVYVGQAQDGISAVKFVYDKSPEEVTGEEHGKSTLLGFEEFVLDyPSEYITAVDGT 231
Cdd:PLN02193   2 AQKLEAKGGETGDVWDDGVYDNVRKVYVGQGQYGIAFVKFEYVNGSQVVVGDEHGKKTELGVEEFEID-ADDYIVYVEGY 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 30684050  232 YDKIFGSDGSVITMLRFKTNK-QTSPPFGLEAGTVFELkeEGHKIVGFHGRADVLLHKIGVHV 293
Cdd:PLN02193  81 REKVNDMTSEMITFLSFKTYKgKTSHPIEKRPGVKFVL--QGGKIVGFHGRSTDVLHSLGAYI 141
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 14-141 1.05e-39

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 135.05  E-value: 1.05e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050     14 NLWDDGStHDAVTKIQLAAGIDGIQYVQFDYVKnGQPEQAPLRGTKGRVLPadpFVINHPDEHLVSVEGWYSPEGIIQGI 93
Cdd:smart00915   2 TEWDDGA-FDGVRKIYVGQGGEGIKSIQFDYDK-GGKVWGDEHGGKGGTGE---EILLYPGEYITSVEGTYDKSGVITSL 76

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 30684050     94 KFISNK-KTSDVIGSDEGTHFTLQ-VKDKKIIGFHG-SAGGNLNSLGAYFA 141
Cdd:smart00915  77 TFKTNKgRTSPFGGYEGGTKFVLEsKEGKKIVGFHGrSSGDGLDSLGAYFS 127
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 16-141 9.57e-39

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 132.69  E-value: 9.57e-39
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050  16 WDDGSTHDAVTKIQLAAGIDGIQYVQFDYVKNGQPEQAPLRGTKGRVlpADPFVINHPDEHLVSVEGWY---SPEGIIQG 92
Cdd:cd09612   4 WDDGVFPDGLRKITVRSGENGIDSIKFEYDKDGQHVVGPWHGGGGGT--PEEIVLDYPDEYITSVSGTYgpvSGSNVITS 81

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*....
gi 30684050  93 IKFISNKKTSDVIGSDEGTHFTLQVKDKKIIGFHGSAGGNLNSLGAYFA 141
Cdd:cd09612  82 LTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYVS 130
 
Name Accession Description Interval E-value
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 163-295 5.14e-63

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 195.19  E-value: 5.14e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050   163 GTVWDDGAYVGVKKVYVGQAQDGISAVKFVYDKSPEEVTGEEHGKSTLLGFEEFVLDYPSEYITAVDGTYDKIFGSDGSV 242
Cdd:pfam01419   1 GASWDDGVYDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDYPDEYITSVEGTYDKVFGSDSEV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 30684050   243 ITMLRFKTNKQ-TSPPFGLEAGTVFELKEEGHKIVGFHGRADVLLHKIGVHVRP 295
Cdd:pfam01419  81 ITSLTFKTNKGrTSPFFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYFAP 134
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 163-294 4.14e-50

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 161.97  E-value: 4.14e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050 163 GTVWDDGAYV-GVKKVYVGQAQDGISAVKFVYDKSPEEVTGEEHGKSTLlGFEEFVLDYPSEYITAVDGTYDKIFGSDgs 241
Cdd:cd09612   1 GSAWDDGVFPdGLRKITVRSGENGIDSIKFEYDKDGQHVVGPWHGGGGG-TPEEIVLDYPDEYITSVSGTYGPVSGSN-- 77

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|...
gi 30684050 242 VITMLRFKTNKQTSPPFGLEAGTVFELKEEGHKIVGFHGRADVLLHKIGVHVR 294
Cdd:cd09612  78 VITSLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYVS 130
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 163-295 2.34e-48

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 157.39  E-value: 2.34e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050    163 GTVWDDGAYVGVKKVYVGQAQDGISAVKFVYDKSpEEVTGEEHGKSTLLGFeeFVLDYPSEYITAVDGTYDKIfgsdgSV 242
Cdd:smart00915   1 GTEWDDGAFDGVRKIYVGQGGEGIKSIQFDYDKG-GKVWGDEHGGKGGTGE--EILLYPGEYITSVEGTYDKS-----GV 72

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 30684050    243 ITMLRFKTNK-QTSPPFGLEAGTVFELK-EEGHKIVGFHGR-ADVLLHKIGVHVRP 295
Cdd:smart00915  73 ITSLTFKTNKgRTSPFGGYEGGTKFVLEsKEGKKIVGFHGRsSGDGLDSLGAYFSP 128
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 14-141 6.36e-48

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 156.67  E-value: 6.36e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050    14 NLWDDGsTHDAVTKIQLAAGIDGIQYVQFDYVKNGQPEQAPLRGTKGRvLPADPFVINHPDEHLVSVEGWYSP-----EG 88
Cdd:pfam01419   2 ASWDDG-VYDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGL-LGPEEFEIDYPDEYITSVEGTYDKvfgsdSE 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 30684050    89 IIQGIKFISNK-KTSDVIGSDEGTHFTLQVKDKKIIGFHGSAGGNLNSLGAYFA 141
Cdd:pfam01419  80 VITSLTFKTNKgRTSPFFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYFA 133
PLN02193 PLN02193
nitrile-specifier protein
 152-293 6.21e-40

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 145.10  E-value: 6.21e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050  152 AKQLTAFGSDDGTVWDDGAYVGVKKVYVGQAQDGISAVKFVYDKSPEEVTGEEHGKSTLLGFEEFVLDyPSEYITAVDGT 231
Cdd:PLN02193   2 AQKLEAKGGETGDVWDDGVYDNVRKVYVGQGQYGIAFVKFEYVNGSQVVVGDEHGKKTELGVEEFEID-ADDYIVYVEGY 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 30684050  232 YDKIFGSDGSVITMLRFKTNK-QTSPPFGLEAGTVFELkeEGHKIVGFHGRADVLLHKIGVHV 293
Cdd:PLN02193  81 REKVNDMTSEMITFLSFKTYKgKTSHPIEKRPGVKFVL--QGGKIVGFHGRSTDVLHSLGAYI 141
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 14-141 1.05e-39

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 135.05  E-value: 1.05e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050     14 NLWDDGStHDAVTKIQLAAGIDGIQYVQFDYVKnGQPEQAPLRGTKGRVLPadpFVINHPDEHLVSVEGWYSPEGIIQGI 93
Cdd:smart00915   2 TEWDDGA-FDGVRKIYVGQGGEGIKSIQFDYDK-GGKVWGDEHGGKGGTGE---EILLYPGEYITSVEGTYDKSGVITSL 76

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 30684050     94 KFISNK-KTSDVIGSDEGTHFTLQ-VKDKKIIGFHG-SAGGNLNSLGAYFA 141
Cdd:smart00915  77 TFKTNKgRTSPFGGYEGGTKFVLEsKEGKKIVGFHGrSSGDGLDSLGAYFS 127
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 16-141 9.57e-39

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 132.69  E-value: 9.57e-39
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050  16 WDDGSTHDAVTKIQLAAGIDGIQYVQFDYVKNGQPEQAPLRGTKGRVlpADPFVINHPDEHLVSVEGWY---SPEGIIQG 92
Cdd:cd09612   4 WDDGVFPDGLRKITVRSGENGIDSIKFEYDKDGQHVVGPWHGGGGGT--PEEIVLDYPDEYITSVSGTYgpvSGSNVITS 81

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*....
gi 30684050  93 IKFISNKKTSDVIGSDEGTHFTLQVKDKKIIGFHGSAGGNLNSLGAYFA 141
Cdd:cd09612  82 LTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYVS 130
Jacalin_like cd09302
Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly ...
 177-291 2.69e-09

Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. Taxonomic distribution is not restricted to plants, the domain is also found in various mammalian proteins, for example.


Pssm-ID: 187706  Cd Length: 128  Bit Score: 54.33  E-value: 2.69e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050 177 VYVGQAqdgISAVKFVYDkspeEVTGEEHGKSTLLGFEEFVLDyPSEYITAVDGTYDKIfgSDGSVITMLRFKTNKQTSP 256
Cdd:cd09302  19 VRSGGA---VDAIRVVLR----DYTDGRHGGNGGPNTSSVFLD-PGEYITITSVSSGDN--GGGTRIDAIQFTTNKGRSG 88

                        90       100       110
                ....*....|....*....|....*....|....*...
gi 30684050 257 PFG---LEAGTVFELkEEGHKIVGFHGRADVLLHKIGV 291
Cdd:cd09302  89 TYGttsGALGTEFTV-PVGGEIVGIYGRAGDDVDAFGF 125
Jacalin_like cd09302
Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly ...
 17-137 4.57e-05

Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. Taxonomic distribution is not restricted to plants, the domain is also found in various mammalian proteins, for example.


Pssm-ID: 187706  Cd Length: 128  Bit Score: 42.39  E-value: 4.57e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050  17 DDGSTHDAVTKIQLAAG--IDGIQYVQFDYVkngqpeqAPLRGTKGRVLPADPFVINHPDEHLVSVEGWYSPEG-IIQGI 93
Cdd:cd09302   6 DTGGDGARLTEIRVRSGgaVDAIRVVLRDYT-------DGRHGGNGGPNTSSVFLDPGEYITITSVSSGDNGGGtRIDAI 78

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 30684050  94 KFISNKKTSDVIGS---DEGTHFTLQVKdKKIIGFHGSAGGNLNSLG 137
Cdd:cd09302  79 QFTTNKGRSGTYGTtsgALGTEFTVPVG-GEIVGIYGRAGDDVDAFG 124
Jacalin_ZG16_like cd09611
Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins; ZG16p is a ...
 159-292 8.14e-05

Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins; ZG16p is a conserved secreted vertebrate protein with tissue-specific expression profiles, which might play a role in glycoprotein secretion, perhaps as a linker protein that participates in the formation and/or transport of the zymogen granule. Its paralog ZG16b (PAUF) has been associated with roles in gene regulation and cancer. This domain family also contains mammalian proteins labelled as prostatic spermine-binding protein (SBP) and salivary-gland specific secreted proteins.


Pssm-ID: 187707 [Multi-domain]  Cd Length: 128  Bit Score: 41.54  E-value: 8.14e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050 159 GSDDGTVWDDGAYVG--VKKVYVGQAQDGISAVKFVYDKSPEEVTGEEHGKstllgFEEFVLDyPSEYITAVDGTYDKIf 236
Cdd:cd09611   1 GSGGGKYFSDVGEGGgpITGIRVSVGNNYIKGIQVRYGSNWSDVYGGRGGN-----EQEIVLE-PGESITKVSGSYKIY- 73

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 30684050 237 gsdgsvITMLRFKTNKQTSPPFGLEAGTVF--ELKEEGHKIVGFHGRADVL-LHKIGVH 292
Cdd:cd09611  74 ------LHGLVFTTNKGRYLSFGKLRGRSFnaTPPPSNYVLRGISGRYGGLgIKSIGFH 126
Jacalin_ZG16_like cd09611
Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins; ZG16p is a ...
 25-139 3.07e-03

Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins; ZG16p is a conserved secreted vertebrate protein with tissue-specific expression profiles, which might play a role in glycoprotein secretion, perhaps as a linker protein that participates in the formation and/or transport of the zymogen granule. Its paralog ZG16b (PAUF) has been associated with roles in gene regulation and cancer. This domain family also contains mammalian proteins labelled as prostatic spermine-binding protein (SBP) and salivary-gland specific secreted proteins.


Pssm-ID: 187707 [Multi-domain]  Cd Length: 128  Bit Score: 36.92  E-value: 3.07e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050  25 VTKIQLAAGIDGIQYVQFDYVKNgqpeQAPLRGTKGRvlPADPFVInHPDEHLVSVEGWYSPegIIQGIKFISNKKTSDV 104
Cdd:cd09611  18 ITGIRVSVGNNYIKGIQVRYGSN----WSDVYGGRGG--NEQEIVL-EPGESITKVSGSYKI--YLHGLVFTTNKGRYLS 88

                        90       100       110
                ....*....|....*....|....*....|....*...
gi 30684050 105 IGSDEGTHFTLQ--VKDKKIIGFHGSAGGN-LNSLGAY 139
Cdd:cd09611  89 FGKLRGRSFNATppPSNYVLRGISGRYGGLgIKSIGFH 126
griffithsin_like cd09614
Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin ...
 205-293 7.05e-03

Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin isolated from a red alga, which has shown potential as an inhibitor of viral entry, exhibiting antiviral activity against HIV and SARS. The biological functions of griffithsin and griffithsin-like proteins with respect to their source organisms are not known.


Pssm-ID: 187710  Cd Length: 128  Bit Score: 35.84  E-value: 7.05e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684050 205 HGKSTllGFEEFVLDYPS-EYITAVDGTYdkifgsdGSVITMLRFKTNKQTSP-PFGLEAGTVFELK-EEGHKIVGFHGR 281
Cdd:cd09614  44 HGGGG--GNLSPTLNFSSgEYITEVTGRS-------GDRVDQVQFTTNYGGRTlPGGGGGGSAFTWTvPDNQKVIGFAGR 114

                        90
                ....*....|..
gi 30684050 282 ADVLLHKIGVHV 293
Cdd:cd09614 115 SGSYLDQLQVYY 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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