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Conserved domains on  [gi|30679979|ref|NP_850524|]
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importin alpha isoform 1 [Arabidopsis thaliana]

Protein Classification

armadillo/beta-catenin-like repeat-containing protein( domain architecture ID 1000979)

armadillo/beta-catenin-like repeat-containing protein similar to Saccharomyces cerevisiae vacuolar protein 8 that functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SRP1 super family cl34886
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
10-530 0e+00

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


The actual alignment was detected with superfamily member COG5064:

Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 617.67  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979  10 EVRRNRY--KVAVDAEEGRRRREDNMVEIRKSKREESLMKKRRegMQALQGFPSASAASVD-KKLDSLKDMVAGVWSDDP 86
Cdd:COG5064   8 EARRYNFkgKGRFSADELRRRREEQQVELRKQKREELLNKRRN--LADVSEEAESSFIPMEqQFYSELPQLTQQLFSDDI 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979  87 ALQLESTTQFRKLLSIERSPPIEEVISAGVVPRFVEFLKKEDYPAIQFEAAWALTNIASGTSDHTKVVIDHNAVPIFVQL 166
Cdd:COG5064  86 EQQLQAVYKFRKLLSKETSPPIQPVIDAGVVPRFVEFMDEIQRDMLQFEAAWALTNIASGTTQQTKVVVDAGAVPLFIQL 165

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979 167 LASPSDDVREQAVWALGNVAGDSPRCRDLVLGCGALLPLLNQLNEHA-KLSMLRNATWTLSNFCRGK-PQPHFDQVKPAL 244
Cdd:COG5064 166 LSSTEDDVREQAVWALGNIAGDSEGCRDYVLQCGALEPLLGLLLSSAiHISMLRNATWTLSNLCRGKnPPPDWSNISQAL 245

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979 245 PALERLIHSDDEEVLTDACWALSYLSDGTNDKIQTVIQAGVVPKLVELLLHHSPSVLIPALRTVGNIVTGDDIQTQCVIN 324
Cdd:COG5064 246 PILAKLIYSRDPEVLVDACWAISYLSDGPNEKIQAVLDVGIPGRLVELLSHESAKIQTPALRSVGNIVTGSDDQTQVIIN 325

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979 325 SGALPCLANLLTqNHKKSIKKEACWTISNITAGNKDQIQTVVEANLISPLVSLLQNAEFDIKKEAAWAISNATSGGSH-- 402
Cdd:COG5064 326 CGALKAFRSLLS-SPKENIRKEACWTISNITAGNTEQIQAVIDANLIPPLIHLLSSAEYKIKKEACWAISNATSGGLNrp 404

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979 403 DQIKYLVEQGCIKPLCDLLVCPDPRIITVCLEGLENILKVGEAEKnLGHTGDMNYYAQLIDDAEGLEKIENLQSHDNNEI 482
Cdd:COG5064 405 DIIRYLVSQGFIKPLCDLLDVVDNKIIEVALDAIENILKVGEQDR-LRYGKNINIYAVYVEKAGGMDAIHGLQDSVNRTI 483

                       490       500       510       520
                ....*....|....*....|....*....|....*....|....*...
gi 30679979 483 YEKAVKILETYWLEEEDDETQQPPGVDGSqagFQFGGNQApvPSGGFN 530
Cdd:COG5064 484 YDKAYSIIEKFFGEEDAVDELAPETAGNT---FTFGSNVN--QQGNFN 526
 
Name Accession Description Interval E-value
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
10-530 0e+00

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 617.67  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979  10 EVRRNRY--KVAVDAEEGRRRREDNMVEIRKSKREESLMKKRRegMQALQGFPSASAASVD-KKLDSLKDMVAGVWSDDP 86
Cdd:COG5064   8 EARRYNFkgKGRFSADELRRRREEQQVELRKQKREELLNKRRN--LADVSEEAESSFIPMEqQFYSELPQLTQQLFSDDI 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979  87 ALQLESTTQFRKLLSIERSPPIEEVISAGVVPRFVEFLKKEDYPAIQFEAAWALTNIASGTSDHTKVVIDHNAVPIFVQL 166
Cdd:COG5064  86 EQQLQAVYKFRKLLSKETSPPIQPVIDAGVVPRFVEFMDEIQRDMLQFEAAWALTNIASGTTQQTKVVVDAGAVPLFIQL 165

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979 167 LASPSDDVREQAVWALGNVAGDSPRCRDLVLGCGALLPLLNQLNEHA-KLSMLRNATWTLSNFCRGK-PQPHFDQVKPAL 244
Cdd:COG5064 166 LSSTEDDVREQAVWALGNIAGDSEGCRDYVLQCGALEPLLGLLLSSAiHISMLRNATWTLSNLCRGKnPPPDWSNISQAL 245

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979 245 PALERLIHSDDEEVLTDACWALSYLSDGTNDKIQTVIQAGVVPKLVELLLHHSPSVLIPALRTVGNIVTGDDIQTQCVIN 324
Cdd:COG5064 246 PILAKLIYSRDPEVLVDACWAISYLSDGPNEKIQAVLDVGIPGRLVELLSHESAKIQTPALRSVGNIVTGSDDQTQVIIN 325

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979 325 SGALPCLANLLTqNHKKSIKKEACWTISNITAGNKDQIQTVVEANLISPLVSLLQNAEFDIKKEAAWAISNATSGGSH-- 402
Cdd:COG5064 326 CGALKAFRSLLS-SPKENIRKEACWTISNITAGNTEQIQAVIDANLIPPLIHLLSSAEYKIKKEACWAISNATSGGLNrp 404

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979 403 DQIKYLVEQGCIKPLCDLLVCPDPRIITVCLEGLENILKVGEAEKnLGHTGDMNYYAQLIDDAEGLEKIENLQSHDNNEI 482
Cdd:COG5064 405 DIIRYLVSQGFIKPLCDLLDVVDNKIIEVALDAIENILKVGEQDR-LRYGKNINIYAVYVEKAGGMDAIHGLQDSVNRTI 483

                       490       500       510       520
                ....*....|....*....|....*....|....*....|....*...
gi 30679979 483 YEKAVKILETYWLEEEDDETQQPPGVDGSqagFQFGGNQApvPSGGFN 530
Cdd:COG5064 484 YDKAYSIIEKFFGEEDAVDELAPETAGNT---FTFGSNVN--QQGNFN 526
IBB pfam01749
Importin beta binding domain; This family consists of the importin alpha (karyopherin alpha), ...
 12-94 1.28e-33

Importin beta binding domain; This family consists of the importin alpha (karyopherin alpha), importin beta (karyopherin beta) binding domain. The domain mediates formation of the importin alpha beta complex; required for classical NLS import of proteins into the nucleus, through the nuclear pore complex and across the nuclear envelope. Also in the alignment is the NLS of importin alpha which overlaps with the IBB domain.


Pssm-ID: 460311 [Multi-domain]  Cd Length: 79  Bit Score: 122.26  E-value: 1.28e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979    12 RRNRYKVAV-DAEEGRRRREDNMVEIRKSKREESLMKKRREGMQAlqgfpSASAASVDKKLDSLKDMVAGVWSDDPALQL 90
Cdd:pfam01749   1 RRKSFKNKGkDADELRRRREEVQVELRKQKREEQLLKRRNVGAPS-----SSSSSAESQLLESLPEMVQGVNSDDPELQL 75


                  ....
gi 30679979    91 ESTT 94
Cdd:pfam01749  76 EATQ 79
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 147-186 1.56e-09

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 53.20  E-value: 1.56e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 30679979    147 TSDHTKVVIDHNAVPIFVQLLASPSDDVREQAVWALGNVA 186
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLS 40
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 117-376 4.50e-06

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 49.72  E-value: 4.50e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979   117 VPRFVEFLKKEDYPAIQFEAAWA-LTNIASGTSDHTKVVIDH-NAVPIFVQLLASPSDDVREQAVWALGNVAGDSP-RCR 193
Cdd:PLN03200   15 VAQCIEQLRAKSSSPQEKELTTArLLELAKTREEARKAIGSHsQAMPLLVSLLRSGTLGAKVNAAAVLGVLCKEEDlRVK 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979   194 DLVLGC-GALLPLLNQLNEHAKlsmlRNATWTLSNFCRGKPQPHF-------DQVKPALPALERLIHSDDEEVLTDACWA 265
Cdd:PLN03200   95 VLLGGCiPPLLSLLKSGSAEAQ----KAAAEAIYAVSSGGLSDHVgskifstEGVVPSLWDQLQPGNKQDKVVEGLLTGA 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979   266 LSYLSDGTNDKIQTVIQAGVVPKLVELLLHHSPSVLIPALRTVGNIVTGDDIQTQCVINSGALPCLANLLTQNHKKSIKK 345
Cdd:PLN03200  171 LRNLCGSTDGFWSATLEAGGVDILVKLLSSGNSDAQANAASLLARLMMAFESSISKVLDAGAVKQLLKLLGQGNEVSVRA 250

                         250       260       270
                  ....*....|....*....|....*....|.
gi 30679979   346 EACWTISNITAGNKDQIQTVVEANLISPLVS 376
Cdd:PLN03200  251 EAAGALEALSSQSKEAKQAIADAGGIPALIN 281
 
Name Accession Description Interval E-value
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
10-530 0e+00

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 617.67  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979  10 EVRRNRY--KVAVDAEEGRRRREDNMVEIRKSKREESLMKKRRegMQALQGFPSASAASVD-KKLDSLKDMVAGVWSDDP 86
Cdd:COG5064   8 EARRYNFkgKGRFSADELRRRREEQQVELRKQKREELLNKRRN--LADVSEEAESSFIPMEqQFYSELPQLTQQLFSDDI 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979  87 ALQLESTTQFRKLLSIERSPPIEEVISAGVVPRFVEFLKKEDYPAIQFEAAWALTNIASGTSDHTKVVIDHNAVPIFVQL 166
Cdd:COG5064  86 EQQLQAVYKFRKLLSKETSPPIQPVIDAGVVPRFVEFMDEIQRDMLQFEAAWALTNIASGTTQQTKVVVDAGAVPLFIQL 165

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979 167 LASPSDDVREQAVWALGNVAGDSPRCRDLVLGCGALLPLLNQLNEHA-KLSMLRNATWTLSNFCRGK-PQPHFDQVKPAL 244
Cdd:COG5064 166 LSSTEDDVREQAVWALGNIAGDSEGCRDYVLQCGALEPLLGLLLSSAiHISMLRNATWTLSNLCRGKnPPPDWSNISQAL 245

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979 245 PALERLIHSDDEEVLTDACWALSYLSDGTNDKIQTVIQAGVVPKLVELLLHHSPSVLIPALRTVGNIVTGDDIQTQCVIN 324
Cdd:COG5064 246 PILAKLIYSRDPEVLVDACWAISYLSDGPNEKIQAVLDVGIPGRLVELLSHESAKIQTPALRSVGNIVTGSDDQTQVIIN 325

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979 325 SGALPCLANLLTqNHKKSIKKEACWTISNITAGNKDQIQTVVEANLISPLVSLLQNAEFDIKKEAAWAISNATSGGSH-- 402
Cdd:COG5064 326 CGALKAFRSLLS-SPKENIRKEACWTISNITAGNTEQIQAVIDANLIPPLIHLLSSAEYKIKKEACWAISNATSGGLNrp 404

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979 403 DQIKYLVEQGCIKPLCDLLVCPDPRIITVCLEGLENILKVGEAEKnLGHTGDMNYYAQLIDDAEGLEKIENLQSHDNNEI 482
Cdd:COG5064 405 DIIRYLVSQGFIKPLCDLLDVVDNKIIEVALDAIENILKVGEQDR-LRYGKNINIYAVYVEKAGGMDAIHGLQDSVNRTI 483

                       490       500       510       520
                ....*....|....*....|....*....|....*....|....*...
gi 30679979 483 YEKAVKILETYWLEEEDDETQQPPGVDGSqagFQFGGNQApvPSGGFN 530
Cdd:COG5064 484 YDKAYSIIEKFFGEEDAVDELAPETAGNT---FTFGSNVN--QQGNFN 526
IBB pfam01749
Importin beta binding domain; This family consists of the importin alpha (karyopherin alpha), ...
 12-94 1.28e-33

Importin beta binding domain; This family consists of the importin alpha (karyopherin alpha), importin beta (karyopherin beta) binding domain. The domain mediates formation of the importin alpha beta complex; required for classical NLS import of proteins into the nucleus, through the nuclear pore complex and across the nuclear envelope. Also in the alignment is the NLS of importin alpha which overlaps with the IBB domain.


Pssm-ID: 460311 [Multi-domain]  Cd Length: 79  Bit Score: 122.26  E-value: 1.28e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979    12 RRNRYKVAV-DAEEGRRRREDNMVEIRKSKREESLMKKRREGMQAlqgfpSASAASVDKKLDSLKDMVAGVWSDDPALQL 90
Cdd:pfam01749   1 RRKSFKNKGkDADELRRRREEVQVELRKQKREEQLLKRRNVGAPS-----SSSSSAESQLLESLPEMVQGVNSDDPELQL 75


                  ....
gi 30679979    91 ESTT 94
Cdd:pfam01749  76 EATQ 79
Arm_3 pfam16186
Atypical Arm repeat; This atypical Arm repeat appears at the very C-terminus of eukaryotic ...
 460-503 1.10e-17

Atypical Arm repeat; This atypical Arm repeat appears at the very C-terminus of eukaryotic proteins such as importin subunit alpha-2, as the last of the repeating units.


Pssm-ID: 465050 [Multi-domain]  Cd Length: 49  Bit Score: 76.47  E-value: 1.10e-17
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 30679979   460 QLIDDAEGLEKIENLQSHDNNEIYEKAVKILETYWLEEEDDETQ 503
Cdd:pfam16186   1 LLIEEAGGLDKIEALQNHENEEIYKKAYKIIEKYFSDEEEEDDE 44
HEAT COG1413
HEAT repeat [General function prediction only];
136-311 1.21e-10

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 59.26  E-value: 1.21e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979 136 AAWALTNIAsgtsdhtkvviDHNAVPIFVQLLASPSDDVREQAVWALGNVagDSPRCRDlvlgcgALLPLLNQLNEHAKl 215
Cdd:COG1413   5 AARALGRLG-----------DPAAVPALIAALADEDPDVRAAAARALGRL--GDPRAVP------ALLEALKDPDPEVR- 64

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979 216 smlRNATWTLSNFcrGKPQphfdqvkpALPALERLIHSDDEEVLTDACWALSYLSDgtndkiqtviqAGVVPKLVELLLH 295
Cdd:COG1413  65 ---AAAAEALGRI--GDPE--------AVPALIAALKDEDPEVRRAAAEALGRLGD-----------PAAVPALLEALKD 120

                       170
                ....*....|....*.
gi 30679979 296 HSPSVLIPALRTVGNI 311
Cdd:COG1413 121 PDWEVRRAAARALGRL 136
HEAT COG1413
HEAT repeat [General function prediction only];
113-266 3.06e-10

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 58.10  E-value: 3.06e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979 113 SAGVVPRFVEFLKKEDyPAIQFEAAWALTNIAsgtsdhtkvviDHNAVPIFVQLLASPSDDVREQAVWALGNvagdsprc 192
Cdd:COG1413  14 DPAAVPALIAALADED-PDVRAAAARALGRLG-----------DPRAVPALLEALKDPDPEVRAAAAEALGR-------- 73

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 30679979 193 rdlvLGCGALLPLLNQLNEHAKLSMLRNATWTLSNFcrgkpqphfdQVKPALPALERLIHSDDEEVLTDACWAL 266
Cdd:COG1413  74 ----IGDPEAVPALIAALKDEDPEVRRAAAEALGRL----------GDPAAVPALLEALKDPDWEVRRAAARAL 133
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 358-398 6.01e-10

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 54.38  E-value: 6.01e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 30679979   358 NKDQIQTVVEANLISPLVSLLQNAEFDIKKEAAWAISNATS 398
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 147-186 9.99e-10

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 54.00  E-value: 9.99e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 30679979   147 TSDHTKVVIDHNAVPIFVQLLASPSDDVREQAVWALGNVA 186
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
HEAT_EZ pfam13513
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ...
 130-185 1.24e-09

HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.


Pssm-ID: 463906 [Multi-domain]  Cd Length: 55  Bit Score: 53.91  E-value: 1.24e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 30679979   130 PAIQFEAAWALTNIASGTSDHTKVVIDhNAVPIFVQLLASPSDDVREQAVWALGNV 185
Cdd:pfam13513   1 WRVREAAALALGSLAEGGPDLLAPAVP-ELLPALLPLLNDDSDLVREAAAWALGRL 55
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 147-186 1.56e-09

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 53.20  E-value: 1.56e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 30679979    147 TSDHTKVVIDHNAVPIFVQLLASPSDDVREQAVWALGNVA 186
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLS 40
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 105-145 7.72e-09

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 51.30  E-value: 7.72e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 30679979   105 SPPIEEVISAGVVPRFVEFLKKEDyPAIQFEAAWALTNIAS 145
Cdd:pfam00514   2 PENKQAVIEAGAVPPLVRLLSSPD-EEVQEEAAWALSNLAA 41
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 358-398 6.91e-08

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 48.58  E-value: 6.91e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 30679979    358 NKDQIQTVVEANLISPLVSLLQNAEFDIKKEAAWAISNATS 398
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 273-313 7.87e-08

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 48.60  E-value: 7.87e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 30679979   273 TNDKIQTVIQAGVVPKLVELLLHHSPSVLIPALRTVGNIVT 313
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 318-356 8.34e-08

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 48.22  E-value: 8.34e-08
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 30679979   318 QTQCVINSGALPCLANLLtQNHKKSIKKEACWTISNITA 356
Cdd:pfam00514   4 NKQAVIEAGAVPPLVRLL-SSPDEEVQEEAAWALSNLAA 41
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 104-145 2.92e-07

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 47.04  E-value: 2.92e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 30679979    104 RSPPIEEVISAGVVPRFVEFLKKEDyPAIQFEAAWALTNIAS 145
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSED-EEVVKEAAWALSNLSS 41
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 273-312 4.07e-07

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 46.27  E-value: 4.07e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 30679979    273 TNDKIQTVIQAGVVPKLVELLLHHSPSVLIPALRTVGNIV 312
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLS 40
HEAT COG1413
HEAT repeat [General function prediction only];
241-395 5.66e-07

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 48.86  E-value: 5.66e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979 241 KPALPALERLIHSDDEEVLTDACWALSYLSDgtndkiqtviqAGVVPKLVELLLHHSPSVLIPALRTVGNIvtGDDiqtq 320
Cdd:COG1413  15 PAAVPALIAALADEDPDVRAAAARALGRLGD-----------PRAVPALLEALKDPDPEVRAAAAEALGRI--GDP---- 77

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 30679979 321 cvinsGALPCLANLLtQNHKKSIKKEACWTISNITagnkdqiqtvvEANLISPLVSLLQNAEFDIKKEAAWAISN 395
Cdd:COG1413  78 -----EAVPALIAAL-KDEDPEVRRAAAEALGRLG-----------DPAAVPALLEALKDPDWEVRRAAARALGR 135
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 315-356 1.00e-06

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 45.50  E-value: 1.00e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 30679979    315 DDIQTQCVINSGALPCLANLLTQNHKKsIKKEACWTISNITA 356
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEE-VVKEAAWALSNLSS 41
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 401-439 2.48e-06

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 44.37  E-value: 2.48e-06
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 30679979   401 SHDQIKYLVEQGCIKPLCDLLVCPDPRIITVCLEGLENI 439
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNL 39
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 243-271 3.05e-06

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 43.98  E-value: 3.05e-06
                          10        20
                  ....*....|....*....|....*....
gi 30679979   243 ALPALERLIHSDDEEVLTDACWALSYLSD 271
Cdd:pfam00514  13 AVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 401-439 3.07e-06

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 43.96  E-value: 3.07e-06
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 30679979    401 SHDQIKYLVEQGCIKPLCDLLVCPDPRIITVCLEGLENI 439
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNL 39
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 117-376 4.50e-06

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 49.72  E-value: 4.50e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979   117 VPRFVEFLKKEDYPAIQFEAAWA-LTNIASGTSDHTKVVIDH-NAVPIFVQLLASPSDDVREQAVWALGNVAGDSP-RCR 193
Cdd:PLN03200   15 VAQCIEQLRAKSSSPQEKELTTArLLELAKTREEARKAIGSHsQAMPLLVSLLRSGTLGAKVNAAAVLGVLCKEEDlRVK 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979   194 DLVLGC-GALLPLLNQLNEHAKlsmlRNATWTLSNFCRGKPQPHF-------DQVKPALPALERLIHSDDEEVLTDACWA 265
Cdd:PLN03200   95 VLLGGCiPPLLSLLKSGSAEAQ----KAAAEAIYAVSSGGLSDHVgskifstEGVVPSLWDQLQPGNKQDKVVEGLLTGA 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979   266 LSYLSDGTNDKIQTVIQAGVVPKLVELLLHHSPSVLIPALRTVGNIVTGDDIQTQCVINSGALPCLANLLTQNHKKSIKK 345
Cdd:PLN03200  171 LRNLCGSTDGFWSATLEAGGVDILVKLLSSGNSDAQANAASLLARLMMAFESSISKVLDAGAVKQLLKLLGQGNEVSVRA 250

                         250       260       270
                  ....*....|....*....|....*....|.
gi 30679979   346 EACWTISNITAGNKDQIQTVVEANLISPLVS 376
Cdd:PLN03200  251 EAAGALEALSSQSKEAKQAIADAGGIPALIN 281
HEAT_EZ pfam13513
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ...
 219-269 4.81e-06

HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.


Pssm-ID: 463906 [Multi-domain]  Cd Length: 55  Bit Score: 43.89  E-value: 4.81e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 30679979   219 RNATWTLSNFCRGKPQPHFDQVKPALPALERLIHSDDEEVLTDACWALSYL 269
Cdd:pfam13513   5 EAAALALGSLAEGGPDLLAPAVPELLPALLPLLNDDSDLVREAAAWALGRL 55
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 189-230 1.20e-05

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 42.44  E-value: 1.20e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 30679979   189 SPRCRDLVLGCGALLPLLNQLNeHAKLSMLRNATWTLSNFCR 230
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLS-SPDEEVQEEAAWALSNLAA 41
HEAT COG1413
HEAT repeat [General function prediction only];
174-311 1.45e-05

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 45.00  E-value: 1.45e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979 174 VREQAVWALGNvagdsprcrdlvLGCGALLPLLNQLNEHAKLSMLRNATWTLSNFCRgkpqphfdqvKPALPALERLIHS 253
Cdd:COG1413   1 VRRAAARALGR------------LGDPAAVPALIAALADEDPDVRAAAARALGRLGD----------PRAVPALLEALKD 58

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 30679979 254 DDEEVLTDACWALSYLSDgtndkiqtviqAGVVPKLVELLLHHSPSVLIPALRTVGNI 311
Cdd:COG1413  59 PDPEVRAAAAEALGRIGD-----------PEAVPALIAALKDEDPEVRRAAAEALGRL 105
HEAT COG1413
HEAT repeat [General function prediction only];
116-186 3.54e-05

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 43.85  E-value: 3.54e-05
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30679979 116 VVPRFVEFLKKEDyPAIQFEAAWALTNIAsgtsdhtkvviDHNAVPIFVQLLASPSDDVREQAVWALGNVA 186
Cdd:COG1413  79 AVPALIAALKDED-PEVRRAAAEALGRLG-----------DPAAVPALLEALKDPDWEVRRAAARALGRLG 137
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 108-183 6.42e-05

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 41.55  E-value: 6.42e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 30679979   108 IEEVISAGVVPRFVEFLKKEDyPAIQFEAAWALTNIAsgtsdhtkvviDHNAVPIFVQLLASPSDD-VREQAVWALG 183
Cdd:pfam13646  24 LGRIGDPEAVPALLELLKDED-PAVRRAAAEALGKIG-----------DPEALPALLELLRDDDDDvVRAAAAEALA 88
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 243-271 6.57e-05

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 40.11  E-value: 6.57e-05
                           10        20
                   ....*....|....*....|....*....
gi 30679979    243 ALPALERLIHSDDEEVLTDACWALSYLSD 271
Cdd:smart00185  13 GLPALVELLKSEDEEVVKEAAWALSNLSS 41
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 117-185 9.13e-05

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 41.17  E-value: 9.13e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 30679979   117 VPRFVEFLKKEDYPAIQFEAAWALTNIASGTsdhtkvvidhnAVPIFVQLLASPSDDVREQAVWALGNV 185
Cdd:pfam13646   1 LPALLQALLRDPDPEVRAAAIRALGRIGDPE-----------AVPALLELLKDEDPAVRRAAAEALGKI 58
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 165-267 3.69e-04

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 39.63  E-value: 3.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979   165 QLLASPSDDVREQAVWALGNVagDSPRCRDlvlgcgALLPLLnqlnEHAKLSMLRNATWTLSNFcrGKPQphfdqvkpAL 244
Cdd:pfam13646   7 ALLRDPDPEVRAAAIRALGRI--GDPEAVP------ALLELL----KDEDPAVRRAAAEALGKI--GDPE--------AL 64

                          90       100
                  ....*....|....*....|....
gi 30679979   245 PALERLIHSD-DEEVLTDACWALS 267
Cdd:pfam13646  65 PALLELLRDDdDDVVRAAAAEALA 88
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 108-187 1.47e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 41.63  E-value: 1.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30679979   108 IEEVISAGVVPRFVEFLKKEDYPAIQFEAAWALTNIASGTSDHTKVVIDHNAVPIFVQLLASPSDDV---------REQA 178
Cdd:PLN03200  224 ISKVLDAGAVKQLLKLLGQGNEVSVRAEAAGALEALSSQSKEAKQAIADAGGIPALINATVAPSKEFmqgefaqalQENA 303


                  ....*....
gi 30679979   179 VWALGNVAG 187
Cdd:PLN03200  304 MGALANICG 312
HEAT pfam02985
HEAT repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see ...
 160-186 1.70e-03

HEAT repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514).


Pssm-ID: 460773  Cd Length: 31  Bit Score: 35.97  E-value: 1.70e-03
                          10        20
                  ....*....|....*....|....*..
gi 30679979   160 VPIFVQLLASPSDDVREQAVWALGNVA 186
Cdd:pfam02985   2 LPLLLKLLNDPSPEVREAAAEALGELA 28
HEAT_EZ pfam13513
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ...
 342-395 2.96e-03

HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.


Pssm-ID: 463906 [Multi-domain]  Cd Length: 55  Bit Score: 36.19  E-value: 2.96e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 30679979   342 SIKKEACWTISNITAGNKDQIQTVVEaNLISPLVSLLQNAEFDIKKEAAWAISN 395
Cdd:pfam13513   2 RVREAAALALGSLAEGGPDLLAPAVP-ELLPALLPLLNDDSDLVREAAAWALGR 54
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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