|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02809 |
PLN02809 |
4-hydroxybenzoate nonaprenyltransferase |
119-407 |
0e+00 |
|
4-hydroxybenzoate nonaprenyltransferase
Pssm-ID: 178405 Cd Length: 289 Bit Score: 518.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 119 YLPEEVRGYAKLARLDKPIGTWLLAWPCMWSIALAADPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTK 198
Cdd:PLN02809 1 YLPPSLRPYAKLARLDKPIGTWLLAWPCMWSIALAAPPGSLPDLKMLALFGCGALLLRGAGCTINDLLDRDIDKKVERTK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 199 LRPIASGLLTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLMKRFTFWPQAFLGLTINWGALLGWTAVK 278
Cdd:PLN02809 81 LRPIASGALTPFQGVGFLGAQLLLGLGILLQLNNYSRILGASSLLLVFTYPLMKRFTFWPQAFLGLTFNWGALLGWAAVK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 279 GSIAPSIVLPLYLSGVCWTLVYDTIYAHQDKEDDVKVGVKSTALRFGDNTKLWLTGFGTASIGFLALSGFSADLGWQYYA 358
Cdd:PLN02809 161 GSLDPAVVLPLYASGVCWTLVYDTIYAHQDKEDDLKVGVKSTALRFGDDTKLWLTGFGAASIGGLALSGYNAGLGWPYYA 240
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 30686272 359 SLAAASGQLGWQIGTADLSSGADCSRKFVSNKWFGAIIFSGVVLGRSFQ 407
Cdd:PLN02809 241 GLAAAAGHLAWQIQTVDLSSRADCNRKFVSNKWFGAIVFAGIVLGKLFS 289
|
|
| PT_UbiA_COQ2 |
cd13959 |
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known ... |
131-403 |
1.94e-111 |
|
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known as Coq2, catalyzes the prenylation of p-hydroxybenzoate with an all-trans polyprenyl group, an important step in ubiquinone (CoQ) biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.
Pssm-ID: 260122 [Multi-domain] Cd Length: 272 Bit Score: 327.50 E-value: 1.94e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 131 ARLDKPIGTWLLAWPCMWSIALAADPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIASGLLTPF 210
Cdd:cd13959 1 MRLDKPIGTLLLLPPALWGLLLAAGGLPLPLLKLLLLFLLGAFLMRSAGCTINDIADRDIDAKVPRTKNRPLASGAISVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 211 QGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLMKRFTFWPQAFLGLTINWGALLGWTAVKGSIaPSIVLPLY 290
Cdd:cd13959 81 EALLFLAVQLLLGLALLLQLNPLTILLSPIALLLVLIYPLMKRFTYWPQLVLGLAFGWGPLMGWAAVTGSL-PLPALLLY 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 291 LSGVCWTLVYDTIYAHQDKEDDVKVGVKSTALRFGDNTKLWLTGFGTASIGFLALSGFSADLGWQYYASLAAASGqLGWQ 370
Cdd:cd13959 160 LAVIFWTAGYDTIYAHQDREDDRKIGVKSTAVLFGDRTKLILALLLHLFVALLLLAGGLAGLGWPYYLGLGAAAH-LLWQ 238
|
250 260 270
....*....|....*....|....*....|....
gi 30686272 371 IGTADLSSGA-DCSRKFVSNKWFGAIIFSGVVLG 403
Cdd:cd13959 239 EHRLDLPDPLrSCLAFFLSNGWVGLLLFAGLLLD 272
|
|
| ubiA_proteo |
TIGR01474 |
4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of ... |
127-403 |
4.85e-111 |
|
4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of integral membrane proteins that condenses para-hydroxybenzoate with any of several polyprenyldiphosphates. Heterologous expression studies suggest that for, many but not all members, the activity seen (e.g. octaprenyltransferase in E. coli) reflects available host isoprenyl pools rather than enzyme specificity. A fairly deep split by both clustering (UPGMA) and phylogenetics (NJ tree) separates this group (mostly Proteobacterial and mitochondrial), with several characterized members, from another group (mostly archaeal and Gram-positive bacterial) lacking characterized members. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]
Pssm-ID: 130539 Cd Length: 281 Bit Score: 326.97 E-value: 4.85e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 127 YAKLARLDKPIGTWLLAWPCMWSIALAADPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIASGL 206
Cdd:TIGR01474 4 YAKLMRADKPIGTLLLLWPCLWSLLLAAQAGGIPPLYLLGLFTVGAILMRGAGCVINDIWDRDFDPQVERTKSRPLASGA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 207 LTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLMKRFTFWPQAFLGLTINWGALLGWTAVKGSIAPSIV 286
Cdd:TIGR01474 84 VSVRQAILFLLVQLLVALGVLLQLNPLTILLGVASLALVATYPFMKRITYWPQLVLGLAFGWGALMGWAAVTGDLSTAAW 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 287 LpLYLSGVCWTLVYDTIYAHQDKEDDVKVGVKSTALRFGDNTKLWLTGFGTASIGFLALSGFSADLGWQYYASLAAASGQ 366
Cdd:TIGR01474 164 V-LYLANILWTLGYDTIYAMQDKEDDIKIGVKSTALRFGDNTKPWLGGLYALMILLLALAGLIAGLGPVYYLGLAAAALL 242
|
250 260 270
....*....|....*....|....*....|....*..
gi 30686272 367 LGWQIGTADLSSGADCSRKFVSNKWFGAIIFSGVVLG 403
Cdd:TIGR01474 243 LIRQIATLDIRDPENCLKLFKANNYVGLLLFAGIALG 279
|
|
| UbiA |
COG0382 |
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate ... |
125-402 |
5.50e-73 |
|
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate polyprenyltransferase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 440151 Cd Length: 280 Bit Score: 229.73 E-value: 5.50e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 125 RGYAKLARLDKPIGTWLLAWPCMWSIALAAdpGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIAS 204
Cdd:COG0382 1 RAYLRLLRLDRPIGILLLLWPTLWALFLAA--GGLPDLLLLLLAVLGTVLMRSAGYVINDYFDREIDRINERKPNRPLAS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 205 GLLTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPL-MKRFTFWPQAFLGLTINWGALLGWTAVKGSIAP 283
Cdd:COG0382 79 GRISLREALLLAIVLLLLALALALLLNPLTFLLALAALALAWAYSLfLKRFTLLGNLVLGLLFGLGILMGFAAVTGSLPL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 284 SIVLpLYLSGVCWTLVYDTIYAHQDKEDDVKVGVKSTALRFGDNTKLWLTG-FGTASIGFLALSGFSADLGWQYYASLAA 362
Cdd:COG0382 159 SAWL-LALAAFLWTLAYDTIYDLEDREGDRKIGIKTLAILFGVRDALIIAGvLYALAVLLLLLLGLLAGLGLLYLLGLLA 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 30686272 363 AsGQLGWQIGTADLSS----GADCSRKFVSNKWFGAIIFSGVVL 402
Cdd:COG0382 238 A-LLLLYLSQLWLLRPrkkdPARALKLFKLNMLLGLLLFLGIAL 280
|
|
| UbiA |
pfam01040 |
UbiA prenyltransferase family; |
142-386 |
1.47e-44 |
|
UbiA prenyltransferase family;
Pssm-ID: 460038 [Multi-domain] Cd Length: 250 Bit Score: 154.69 E-value: 1.47e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 142 LAWPCMWSIALAAdpGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIASGLLTPFQGIGFLGLQLL 221
Cdd:pfam01040 1 LLIPALAGLALAA--GGVPDLLLLLLALLGTVLARAAANALNDYYDRDIDAIMPRTPNRPLPSGRISPREALIFALVLLA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 222 LGLGILLQLNNYSRVLGASSLLLVFSYPL-MKRFTFWPQAFLGLTINWGALLGWTAVKGSIAPSIVLpLYLSGVCWTLVY 300
Cdd:pfam01040 79 LGLLLLLLLNPLTALLGLAALLLYVLYTLrLKRRTLLGQLVGGLAFGLPPLLGWAAVTGSLSPLALL-LALALFLWTWAI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 301 DTIYAHQDKEDDVKVGVKSTALRFGDNTKLWL-TGFGTASIGFLALSGFSADLGWQYYASLAAASGQLGWQIGTADLSSG 379
Cdd:pfam01040 158 ALANDLRDREDDRKAGIKTLPVVLGRKAARILlALLLAVALLLLLLLLLLLLGGLYLLLALLLAALALLYAARLLRLRDP 237
|
....*..
gi 30686272 380 ADCSRKF 386
Cdd:pfam01040 238 KKDAKAF 244
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02809 |
PLN02809 |
4-hydroxybenzoate nonaprenyltransferase |
119-407 |
0e+00 |
|
4-hydroxybenzoate nonaprenyltransferase
Pssm-ID: 178405 Cd Length: 289 Bit Score: 518.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 119 YLPEEVRGYAKLARLDKPIGTWLLAWPCMWSIALAADPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTK 198
Cdd:PLN02809 1 YLPPSLRPYAKLARLDKPIGTWLLAWPCMWSIALAAPPGSLPDLKMLALFGCGALLLRGAGCTINDLLDRDIDKKVERTK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 199 LRPIASGLLTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLMKRFTFWPQAFLGLTINWGALLGWTAVK 278
Cdd:PLN02809 81 LRPIASGALTPFQGVGFLGAQLLLGLGILLQLNNYSRILGASSLLLVFTYPLMKRFTFWPQAFLGLTFNWGALLGWAAVK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 279 GSIAPSIVLPLYLSGVCWTLVYDTIYAHQDKEDDVKVGVKSTALRFGDNTKLWLTGFGTASIGFLALSGFSADLGWQYYA 358
Cdd:PLN02809 161 GSLDPAVVLPLYASGVCWTLVYDTIYAHQDKEDDLKVGVKSTALRFGDDTKLWLTGFGAASIGGLALSGYNAGLGWPYYA 240
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 30686272 359 SLAAASGQLGWQIGTADLSSGADCSRKFVSNKWFGAIIFSGVVLGRSFQ 407
Cdd:PLN02809 241 GLAAAAGHLAWQIQTVDLSSRADCNRKFVSNKWFGAIVFAGIVLGKLFS 289
|
|
| PT_UbiA_COQ2 |
cd13959 |
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known ... |
131-403 |
1.94e-111 |
|
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known as Coq2, catalyzes the prenylation of p-hydroxybenzoate with an all-trans polyprenyl group, an important step in ubiquinone (CoQ) biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.
Pssm-ID: 260122 [Multi-domain] Cd Length: 272 Bit Score: 327.50 E-value: 1.94e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 131 ARLDKPIGTWLLAWPCMWSIALAADPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIASGLLTPF 210
Cdd:cd13959 1 MRLDKPIGTLLLLPPALWGLLLAAGGLPLPLLKLLLLFLLGAFLMRSAGCTINDIADRDIDAKVPRTKNRPLASGAISVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 211 QGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLMKRFTFWPQAFLGLTINWGALLGWTAVKGSIaPSIVLPLY 290
Cdd:cd13959 81 EALLFLAVQLLLGLALLLQLNPLTILLSPIALLLVLIYPLMKRFTYWPQLVLGLAFGWGPLMGWAAVTGSL-PLPALLLY 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 291 LSGVCWTLVYDTIYAHQDKEDDVKVGVKSTALRFGDNTKLWLTGFGTASIGFLALSGFSADLGWQYYASLAAASGqLGWQ 370
Cdd:cd13959 160 LAVIFWTAGYDTIYAHQDREDDRKIGVKSTAVLFGDRTKLILALLLHLFVALLLLAGGLAGLGWPYYLGLGAAAH-LLWQ 238
|
250 260 270
....*....|....*....|....*....|....
gi 30686272 371 IGTADLSSGA-DCSRKFVSNKWFGAIIFSGVVLG 403
Cdd:cd13959 239 EHRLDLPDPLrSCLAFFLSNGWVGLLLFAGLLLD 272
|
|
| ubiA_proteo |
TIGR01474 |
4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of ... |
127-403 |
4.85e-111 |
|
4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of integral membrane proteins that condenses para-hydroxybenzoate with any of several polyprenyldiphosphates. Heterologous expression studies suggest that for, many but not all members, the activity seen (e.g. octaprenyltransferase in E. coli) reflects available host isoprenyl pools rather than enzyme specificity. A fairly deep split by both clustering (UPGMA) and phylogenetics (NJ tree) separates this group (mostly Proteobacterial and mitochondrial), with several characterized members, from another group (mostly archaeal and Gram-positive bacterial) lacking characterized members. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]
Pssm-ID: 130539 Cd Length: 281 Bit Score: 326.97 E-value: 4.85e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 127 YAKLARLDKPIGTWLLAWPCMWSIALAADPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIASGL 206
Cdd:TIGR01474 4 YAKLMRADKPIGTLLLLWPCLWSLLLAAQAGGIPPLYLLGLFTVGAILMRGAGCVINDIWDRDFDPQVERTKSRPLASGA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 207 LTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLMKRFTFWPQAFLGLTINWGALLGWTAVKGSIAPSIV 286
Cdd:TIGR01474 84 VSVRQAILFLLVQLLVALGVLLQLNPLTILLGVASLALVATYPFMKRITYWPQLVLGLAFGWGALMGWAAVTGDLSTAAW 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 287 LpLYLSGVCWTLVYDTIYAHQDKEDDVKVGVKSTALRFGDNTKLWLTGFGTASIGFLALSGFSADLGWQYYASLAAASGQ 366
Cdd:TIGR01474 164 V-LYLANILWTLGYDTIYAMQDKEDDIKIGVKSTALRFGDNTKPWLGGLYALMILLLALAGLIAGLGPVYYLGLAAAALL 242
|
250 260 270
....*....|....*....|....*....|....*..
gi 30686272 367 LGWQIGTADLSSGADCSRKFVSNKWFGAIIFSGVVLG 403
Cdd:TIGR01474 243 LIRQIATLDIRDPENCLKLFKANNYVGLLLFAGIALG 279
|
|
| UbiA |
COG0382 |
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate ... |
125-402 |
5.50e-73 |
|
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate polyprenyltransferase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 440151 Cd Length: 280 Bit Score: 229.73 E-value: 5.50e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 125 RGYAKLARLDKPIGTWLLAWPCMWSIALAAdpGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIAS 204
Cdd:COG0382 1 RAYLRLLRLDRPIGILLLLWPTLWALFLAA--GGLPDLLLLLLAVLGTVLMRSAGYVINDYFDREIDRINERKPNRPLAS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 205 GLLTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPL-MKRFTFWPQAFLGLTINWGALLGWTAVKGSIAP 283
Cdd:COG0382 79 GRISLREALLLAIVLLLLALALALLLNPLTFLLALAALALAWAYSLfLKRFTLLGNLVLGLLFGLGILMGFAAVTGSLPL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 284 SIVLpLYLSGVCWTLVYDTIYAHQDKEDDVKVGVKSTALRFGDNTKLWLTG-FGTASIGFLALSGFSADLGWQYYASLAA 362
Cdd:COG0382 159 SAWL-LALAAFLWTLAYDTIYDLEDREGDRKIGIKTLAILFGVRDALIIAGvLYALAVLLLLLLGLLAGLGLLYLLGLLA 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 30686272 363 AsGQLGWQIGTADLSS----GADCSRKFVSNKWFGAIIFSGVVL 402
Cdd:COG0382 238 A-LLLLYLSQLWLLRPrkkdPARALKLFKLNMLLGLLLFLGIAL 280
|
|
| UbiA |
pfam01040 |
UbiA prenyltransferase family; |
142-386 |
1.47e-44 |
|
UbiA prenyltransferase family;
Pssm-ID: 460038 [Multi-domain] Cd Length: 250 Bit Score: 154.69 E-value: 1.47e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 142 LAWPCMWSIALAAdpGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIASGLLTPFQGIGFLGLQLL 221
Cdd:pfam01040 1 LLIPALAGLALAA--GGVPDLLLLLLALLGTVLARAAANALNDYYDRDIDAIMPRTPNRPLPSGRISPREALIFALVLLA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 222 LGLGILLQLNNYSRVLGASSLLLVFSYPL-MKRFTFWPQAFLGLTINWGALLGWTAVKGSIAPSIVLpLYLSGVCWTLVY 300
Cdd:pfam01040 79 LGLLLLLLLNPLTALLGLAALLLYVLYTLrLKRRTLLGQLVGGLAFGLPPLLGWAAVTGSLSPLALL-LALALFLWTWAI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 301 DTIYAHQDKEDDVKVGVKSTALRFGDNTKLWL-TGFGTASIGFLALSGFSADLGWQYYASLAAASGQLGWQIGTADLSSG 379
Cdd:pfam01040 158 ALANDLRDREDDRKAGIKTLPVVLGRKAARILlALLLAVALLLLLLLLLLLLGGLYLLLALLLAALALLYAARLLRLRDP 237
|
....*..
gi 30686272 380 ADCSRKF 386
Cdd:pfam01040 238 KKDAKAF 244
|
|
| ubiA |
PRK12873 |
4-hydroxybenzoate polyprenyltransferase; |
122-404 |
1.40e-34 |
|
4-hydroxybenzoate polyprenyltransferase;
Pssm-ID: 171787 [Multi-domain] Cd Length: 294 Bit Score: 129.78 E-value: 1.40e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 122 EEVRGYAKLARLDKPIGTWLLAWPCMWSIALAadPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRP 201
Cdd:PRK12873 5 IKLSPWFELLRWNKPTGRLILLIPAGWSLWLT--PSAPPSLLLLLLIILGGLAVSGAGCIANDLWDRRIDRKVERTKNRP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 202 IASGLLTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGAS----SLLLVFSYPLMKRFTFWPQAFLGLTINWGALLGWTAV 277
Cdd:PRK12873 83 LARGKISLKTAYSLLIVLLLLSLFVVLSLPQPSRNLCLSlaflALPPILIYPSAKRWFAYPQAILALCWGFAVLIPWAAA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 278 KGSIAPSIVL-PLYLSGVCWTLVYDTIYAHQDKEDDVKVGVKSTALRFGDNTK--LWLTGFGTASigFLALSGFSADLGW 354
Cdd:PRK12873 163 EGSLNGGWPLlFCWLATLLWTFGFDTVYAMADRRDDAKIGLNSSALSLGSNALktVQICYFLTSI--FLALAAFIAQVGF 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 30686272 355 QYYASLAAASgqLGWQIGTADLS----SGADCSRKFVSNKWFGAIIFSGVVLGR 404
Cdd:PRK12873 241 IFWPFWLIAS--IGMQRDILKLFpekqSIKTIGNHFSNQVILGSLLLLGLILAR 292
|
|
| PT_UbiA |
cd13956 |
UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA ... |
131-403 |
1.10e-19 |
|
UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.
Pssm-ID: 260119 [Multi-domain] Cd Length: 271 Bit Score: 88.17 E-value: 1.10e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 131 ARLDKPIGTWLLAWPCMWSIALAADPGSLPSFKYMALFGcGALLLRGAGCTINDLLDQDIDTKVDRTklRPIASGLLTPF 210
Cdd:cd13956 1 LRLMRPYTLLYVLAPALAGAALAGAFAGPLPALLLLALL-AVFLGAGAGYALNDYTDRELDAINKPD--RPLPSGRLSPR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 211 QGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLM-KRFTFWPQAFLGLTINWGALLGWTAVKGSIAPSIVLPL 289
Cdd:cd13956 78 QALAFAAALLLVGLALALALGPLALLLLLAGLLLGLAYSLGlKRLKLGGWGVLGYATGLALLPGLGAVAAGGLVPLALLL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 290 YLSGVCWTLVYDTIYAHQDKEDDVKVGVKSTALRFGDNTKLWLTgFGTASIGFLALSGFSADLGWQYYASLAA-ASGQLG 368
Cdd:cd13956 158 ALVFLLLGLGINLYNDLPDVEGDRAAGIRTLPVRLGPRRARRLA-AGLLLAALILVVLLAVAGLLGPLALLALlAVALLA 236
|
250 260 270
....*....|....*....|....*....|....*
gi 30686272 369 WQIGTADLSSGADCSRKFVSNKWFGAIIFSGVVLG 403
Cdd:cd13956 237 LRARFARADRLPALPRGFLLLAVYRLLLFAALLLA 271
|
|
| ubiA |
PRK13106 |
prenyltransferase; Reviewed |
164-403 |
3.00e-18 |
|
prenyltransferase; Reviewed
Pssm-ID: 237283 Cd Length: 300 Bit Score: 84.39 E-value: 3.00e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 164 YMALFGcgallLRGAGCTINDLLDQDIDTKVDRTKLRPIASGLLTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLL 243
Cdd:PRK13106 55 FLALFF-----LRTAGMTNDNLADLEIDAKNPRTKNRPLVTGAIKISEAKALITAGLILFFASAYLVNRWALLLSPIVAL 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 244 LVFSYPLMKRFTFWPQAFLGLTINWGALLGWTAVKGSIAPSIVLPLY-------LSGVCWTLVYDTIYAHQDKEDDVKVG 316
Cdd:PRK13106 130 IAMSYPYMKRYTAFANYHLASIQGLAVFSGAVAVLGLYANSLIQVLLrvpwlfvIGTILWAAGFDLYNHIPDAEFDREMG 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 317 VKSTALRFGDNTKLWLTGFGTASIGFLALSGFSADLGWQYYASLAAASGQLGWQIGTAdlSSGADCSRKFVSNkwfgaiI 396
Cdd:PRK13106 210 LHSFAVVLGKWALTFAGLNQLFSVVLDLLGDLYYGLGPIAIAATILHGLIMAYAYYLA--SKKGDFGRAFYYN------I 281
|
....*..
gi 30686272 397 FSGVVLG 403
Cdd:PRK13106 282 YSSIVLG 288
|
|
| ubiA |
PRK12888 |
4-hydroxybenzoate octaprenyltransferase; |
183-402 |
9.89e-18 |
|
4-hydroxybenzoate octaprenyltransferase;
Pssm-ID: 183814 Cd Length: 284 Bit Score: 82.85 E-value: 9.89e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 183 NDLLDQDIDTKVDRTKLRPIASGLLTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLMKRFTFWPQAFL 262
Cdd:PRK12888 59 NRIIDREIDARNPRTAGRELVTGAVSVRTAWTGALVALAVFLGAAALLNPLCLALAPLAVAPLVVYPYAKRFTNFPHAIL 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 263 GLTINWGALLGWTAVKGSIAPSIVLpLYLSGVCWTLVYDTIYAHQDKEDDVKVGVKSTALRFGDNTKLWL-TGFGTASIG 341
Cdd:PRK12888 139 GLAQAVGPVGAWIAVTGTWSWPAVL-LGLAVGLWIGGFDLIYACQDAEVDRRIGVRSVPARFGVRAALWAsRVAHVVTFA 217
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30686272 342 FLALSGFSADLGWQYYASLAAASGQLGWQigtADLSSGADCSRkfVSNKWFGAIIFSGVVL 402
Cdd:PRK12888 218 LFVWFGLAVGFGALWWIGLAITAGAFAYE---HAIVSPTDLSR--VNRAFFTANGFVGIAL 273
|
|
| ubiA |
PRK12886 |
prenyltransferase; Reviewed |
176-406 |
2.98e-17 |
|
prenyltransferase; Reviewed
Pssm-ID: 237247 Cd Length: 291 Bit Score: 81.66 E-value: 2.98e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 176 RGAGCTINDLLDQDIDTKVDRTKLRPIASGLLTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLMKRFT 255
Cdd:PRK12886 55 RTAAMGFNRLIDAEIDARNPRTAGRAIPAGLISKGSAILFIVLSSLLMLFAAWFLNPLCLYLSPPALFFLLLYSYCKRFT 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 256 FWPQAFLGLTINWGALLGWTAVKGSIAPSIVLpLYLSGVCWTLVYDTIYAHQDKEDDVKVGVKSTALRFGDNTKLWLT-G 334
Cdd:PRK12886 135 ALAHVVLGFCLALAPLGAWIAIRGTIELPAIL-LGLAVLFWVAGFDILYALQDLEFDRKEGLHSIPAKLGVNGSLWIArV 213
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 30686272 335 FGTASIGFLALSGFSADLGWQYYASLAAASGQLGWQigtADLSSGADCSRK----FVSNKWFGAIIFSGVVLGRSF 406
Cdd:PRK12886 214 FHLLMIGFLFALGISAGLGPWFLAGLAVTGILLLYE---HWLLRGGDLTRLdaafFNMNGYISVTLFAATLFDRLF 286
|
|
| CyoE |
COG0109 |
Polyprenyltransferase (heme O synthase) [Coenzyme transport and metabolism, Lipid transport ... |
124-297 |
9.99e-11 |
|
Polyprenyltransferase (heme O synthase) [Coenzyme transport and metabolism, Lipid transport and metabolism];
Pssm-ID: 439879 Cd Length: 299 Bit Score: 62.07 E-value: 9.99e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 124 VRGYAKLArldKPIGTWLL---AWPCMWsiaLAadPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLR 200
Cdd:COG0109 16 LRDYLALT---KPRIILLLlftALAGML---LA--AGGLPDLLLLLLTLLGGALAAGAANALNNYIDRDIDALMKRTKNR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 201 PIASGLLTPFQGIGFLGLQLLLGLGILLQLNN-YSRVLGASSLLL-VFSY-PLMKRFTfwPQAflgltINWGA------- 270
Cdd:COG0109 88 PLPTGRISPREALIFGLVLGVLGLALLALFVNpLAALLGLLGIFFyVVVYtLWLKRRT--PQN-----IVIGGaagampp 160
|
170 180
....*....|....*....|....*....
gi 30686272 271 LLGWTAVKGSIAPsivLPLYLSGV--CWT 297
Cdd:COG0109 161 LIGWAAVTGSLSL---EALLLFLIifLWT 186
|
|
| PT_UbiA_Cox10 |
cd13957 |
Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O ... |
135-297 |
1.94e-09 |
|
Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O synthase, heme A:farnesyltransferase, cytochrome c oxidase subunit X [Cox10]) converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of the heme B porphyrin ring with a hydroxyethyl farnesyl side group. It is localized at the mitochondrial inner membrane. Eukaryotic Cox10 is important for the maturation of the heme A prosthetic group of cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, that catalyzes the electron transfer from reduced cytochrome c to oxygen. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.
Pssm-ID: 260120 Cd Length: 271 Bit Score: 57.83 E-value: 1.94e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 135 KPIGTWLLAWPCMWSIALAadPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIASGLLTPFQGIG 214
Cdd:cd13957 5 KPRITLLVLLTALAGYLLA--PGGVPDLLLLLLTLLGTALVSASANALNQYIERDIDAKMKRTRNRPLPSGRISPKHALI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 215 FLGLQLLL-GLGILLQLNNYSRVLGASSLLL-VFSY-PLMKRFTFWpqaflglTINWGA-------LLGWTAVKGSIAPs 284
Cdd:cd13957 83 FGLVLGILgLALLALFVNPLTALLGLLGIFLyVFVYtPLKKRTTPL-------NTVIGGiagaippLIGWAAATGSLDL- 154
|
170
....*....|....*
gi 30686272 285 ivLPLYLSGV--CWT 297
Cdd:cd13957 155 --GAWLLFLIlfLWQ 167
|
|
| PRK04375 |
PRK04375 |
protoheme IX farnesyltransferase; Provisional |
152-297 |
9.83e-09 |
|
protoheme IX farnesyltransferase; Provisional
Pssm-ID: 235293 Cd Length: 296 Bit Score: 56.30 E-value: 9.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 152 LAADPGSLPSFKYMALFGCGALLLrGAGCTINDLLDQDIDTKVDRTKLRPIASGLLTPFQGIGFLGLQLLLGLGILLQLN 231
Cdd:PRK04375 34 LLAPPGVPPLLLLLLTLLGIALVA-GAAGALNNYIDRDIDAKMERTKNRPLVTGRISPREALIFGLVLGVLGFLLLGLFV 112
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 30686272 232 NY-SRVLGASSLLL-VFSYPL-MKRFTfwPQaflglTINWGA-------LLGWTAVKGSIAPSIVLpLYLSGVCWT 297
Cdd:PRK04375 113 NPlAAWLTLAGIFFyVVVYTLwLKRRT--PQ-----NIVIGGaagamppLIGWAAVTGSLSWEALI-LFLIIFLWT 180
|
|
| ubiA |
PRK12874 |
4-hydroxybenzoate polyprenyltransferase; |
182-363 |
1.09e-08 |
|
4-hydroxybenzoate polyprenyltransferase;
Pssm-ID: 237242 Cd Length: 291 Bit Score: 56.17 E-value: 1.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 182 INDLLDQDIDTKVDRTKLRPIASGLLTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLMKRFTFWPQAF 261
Cdd:PRK12874 66 FNRLVDRDIDKDNPRTANRPSVDGRISVKSMVLFIVLNALIFIGVSYFINPLAFKLSFPFLIVLGGYSYFKRFSSLAHLV 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 262 LGLTINWGALLGWTAVKGSIAP-SIVLPLylsGVC-WTLVYDTIYAHQDKEDDVKVGVKSTALRFGDNTKLWLTGFGTA- 338
Cdd:PRK12874 146 LGLSLGLAPIAGVVAVLGEIPLwSVFLAL---GVMfWVAGFDLLYSLQDMEFDKKRGLHSIPSKFGEKATLFISRLFHLl 222
|
170 180
....*....|....*....|....*.
gi 30686272 339 SIGFLALSGFSADLG-WQYYASLAAA 363
Cdd:PRK12874 223 AVLFWLLFVWCAHLGlFAYLGVIVSA 248
|
|
| ubiA |
PRK12876 |
prenyltransferase; Reviewed |
152-325 |
4.36e-08 |
|
prenyltransferase; Reviewed
Pssm-ID: 237244 Cd Length: 300 Bit Score: 54.37 E-value: 4.36e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 152 LAADPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIASGLLTPFQGIGFLGLQLLLGLGILLQLN 231
Cdd:PRK12876 36 ISFSLFSLGGIKTISLGGSAFFCARTVGIIVNQIIDCAIDKKNPRTSSRVLPAKLLSINFSMLLLTLCSFLFLSLCWLLN 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 232 NYSRVLGASSLLLVFSYPLMKRFTFWPQAFLGLTINWGALLGWTAV-KGSIAPSIVLPLYLSGVCWTLVY---DTIYAHQ 307
Cdd:PRK12876 116 PLCFSLAVLSTLLMIIYPYTKRVTFLCHWILGLVYYLAILMNFFAIiETPLSFSLFCMASLWGISFGMIIaanDIIYAIQ 195
|
170
....*....|....*...
gi 30686272 308 DKEDDVKVGVKSTALRFG 325
Cdd:PRK12876 196 DLEFDRKEGLFSIPARFG 213
|
|
| ubiA |
PRK12895 |
prenyltransferase; Reviewed |
242-403 |
1.65e-06 |
|
prenyltransferase; Reviewed
Pssm-ID: 237251 Cd Length: 286 Bit Score: 49.43 E-value: 1.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 242 LLLVFSYPLMKRFTFWPQAFLGLTINWGALLGWTAVKGSIA--PSIVLpLYLSGVCWTLVYDTIYAHQDKEDDVKVGVKS 319
Cdd:PRK12895 116 IFLFIIDPFLKRYTAWRHIYMGSIIGLGVLAGYLAVIPAFPynLLIYI-IFISSSLWIAGFDIIYVIPDIEYDKINGLKT 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 320 TALRFGDNTKLWLTG-FGTASIGFLALSGFSADLGWqYYASLAAASGQLGWQIGTADLSSGADCSRKFV-SNKWFGAIIF 397
Cdd:PRK12895 195 IMNTYGIKNGLYISDiFHISSLILFWISGIYIRTLW-YLAALIIIYTLVIYQHLIIDPRNPINKRMSFFnANSFIGFVFL 273
|
....*.
gi 30686272 398 SGVVLG 403
Cdd:PRK12895 274 IGIILS 279
|
|
| PLN02776 |
PLN02776 |
prenyltransferase |
171-291 |
1.85e-03 |
|
prenyltransferase
Pssm-ID: 215415 Cd Length: 341 Bit Score: 40.11 E-value: 1.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 171 GALLLRGAGCTINDLLDQDIDTKVDRTKLRPIASGLLT-PFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLL-VFSY 248
Cdd:PLN02776 37 GTMLCAASANTLNQVFEVKNDSKMKRTMRRPLPSGRISvPHAVAWAVVVGAAGVALLAYKTNMLTAGLGAGNILLyAFVY 116
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 30686272 249 PLMKRFTFWpQAFLGLTInwGA---LLGWTAVKGSIAP-SIVLP--LYL 291
Cdd:PLN02776 117 TPLKQIHPA-NTWVGAVV--GAippLMGWAAASGQLDAgAMVLAaaLYF 162
|
|
| ubiA |
PRK12882 |
prenyltransferase; Reviewed |
157-363 |
1.91e-03 |
|
prenyltransferase; Reviewed
Pssm-ID: 183811 Cd Length: 276 Bit Score: 39.96 E-value: 1.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 157 GSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDtKVDRTKlRPIASGLLTPFQGIGflglqlllglgillqlnnYSRV 236
Cdd:PRK12882 32 GILSSPSLTGLAFAAVFLATGAGNAINDYFDREID-RINRPD-RPIPSGAVSPRGALA------------------FSIL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 237 LGASSLLLVFSYPLM----------------KRFTFWPqaFLG-LTInwGALLGWT-----AVKGSIAPSIVLPLYLSGV 294
Cdd:PRK12882 92 LFAAGVALAFLLPPLclaialfnslllvlyaETLKGTP--GLGnASV--AYLTGSTflfggAAVGTEGLLALLVLFALAA 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686272 295 CWTLVYDTIYAHQDKEDDVKVGVKSTALRFGDNTKLWL-TGFGTASIGFLALSGFSADLGWQYYASLAAA 363
Cdd:PRK12882 168 LATLAREIIKDVEDIEGDRAEGARTLPILIGVRKALYVaAAFLLVAVAASPLPYLLSTFGLWYLVLVAPA 237
|
|
| |
