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Conserved domains on  [gi|50962841|ref|NP_796342|]
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protein O-mannosyl-transferase TMTC2 precursor [Mus musculus]

Protein Classification

DUF1736 and TPR domain-containing protein( domain architecture ID 12091460)

DUF1736 and TPR domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 247-321 2.87e-37

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


:

Pssm-ID: 462468  Cd Length: 75  Bit Score: 133.81  E-value: 2.87e-37
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 50962841   247 GNKPPSFSNSDNPAADSDSLLARTLTFLYLPTKNLWLLLCPDTLSFDWSMDAVPLLKTVCDWRNLHTVAFYSGLL 321
Cdd:pfam08409   1 GGQLPVFSASDNPAAFSPSLLTRTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYGALA 75
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
488-707 2.07e-29

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 117.42  E-value: 2.07e-29
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 488 IKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYL 565
Cdd:COG0457   1 LELDPddAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 566 NTGIILMNQGKTEEARRTFLKCSEIpdeNLKDPHAHkssvtsclYNLGKLYHEQGRYEEALSVYREAIQKMPRHfapQSL 645
Cdd:COG0457  81 NLGLALQALGRYEEALEDYDKALEL---DPDDAEAL--------YNLGLALLELGRYDEAIEAYERALELDPDD---ADA 146

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 50962841 646 YNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKFFLKAIELD 707
Cdd:COG0457 147 LYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALR 208
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
608-812 2.14e-25

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 105.86  E-value: 2.14e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 608 CLYNLGKLYHEQGRYEEALSVYREAIQKMPRHfaPQSLYNMmGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLL 687
Cdd:COG0457  10 AYNNLGLAYRRLGRYEEAIEDYEKALELDPDD--AEALYNL-GLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLAL 86

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 688 ALTGRKSEAEKFFLKAIELDPTKGNCYMHYGQFLLEESRLteaaemakkaaeldntefdvvfnaahmlrqaslnEAAEKY 767
Cdd:COG0457  87 QALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRY----------------------------------DEAIEA 132

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*
gi 50962841 768 YDLAARLRPNYPAALMNLGAILHLNGRLQKAEANYLRALQLKPDD 812
Cdd:COG0457 133 YERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAA 177
ArnT super family cl43523
PMT family glycosyltransferase ArnT/Agl22, involved in glycosylation of proteins and lipid IVA ...
 78-198 5.65e-03

PMT family glycosyltransferase ArnT/Agl22, involved in glycosylation of proteins and lipid IVA [Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG1807:

Pssm-ID: 441412 [Multi-domain]  Cd Length: 309  Bit Score: 39.61  E-value: 5.65e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841  78 AIGGLNPWSYHLVNVLLHAAVTGLFTRFSKALLGDGYWtFMAGLMFASHPIHteAVAGIVGRADVGASLFFLLSLLCYIk 157
Cdd:COG1807  77 KLFGVSEFAARLPSALLGLLTVLLVYLLARRLFGRRAA-LLAALLLLTSPLL--LLFGRLATPDALLLLFWTLALYALL- 152

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 50962841 158 hcstRGYSARTWGWFLGTGLCAGCSMLWKEQGVTVLAVSAV 198
Cdd:COG1807 153 ----RALERRRLRWLLLAGLALGLGFLTKGPVALLLPGLAL 189
 
Name Accession Description Interval E-value
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 247-321 2.87e-37

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


Pssm-ID: 462468  Cd Length: 75  Bit Score: 133.81  E-value: 2.87e-37
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 50962841   247 GNKPPSFSNSDNPAADSDSLLARTLTFLYLPTKNLWLLLCPDTLSFDWSMDAVPLLKTVCDWRNLHTVAFYSGLL 321
Cdd:pfam08409   1 GGQLPVFSASDNPAAFSPSLLTRTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYGALA 75
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
488-707 2.07e-29

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 117.42  E-value: 2.07e-29
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 488 IKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYL 565
Cdd:COG0457   1 LELDPddAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 566 NTGIILMNQGKTEEARRTFLKCSEIpdeNLKDPHAHkssvtsclYNLGKLYHEQGRYEEALSVYREAIQKMPRHfapQSL 645
Cdd:COG0457  81 NLGLALQALGRYEEALEDYDKALEL---DPDDAEAL--------YNLGLALLELGRYDEAIEAYERALELDPDD---ADA 146

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 50962841 646 YNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKFFLKAIELD 707
Cdd:COG0457 147 LYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALR 208
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
608-812 2.14e-25

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 105.86  E-value: 2.14e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 608 CLYNLGKLYHEQGRYEEALSVYREAIQKMPRHfaPQSLYNMmGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLL 687
Cdd:COG0457  10 AYNNLGLAYRRLGRYEEAIEDYEKALELDPDD--AEALYNL-GLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLAL 86

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 688 ALTGRKSEAEKFFLKAIELDPTKGNCYMHYGQFLLEESRLteaaemakkaaeldntefdvvfnaahmlrqaslnEAAEKY 767
Cdd:COG0457  87 QALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRY----------------------------------DEAIEA 132

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*
gi 50962841 768 YDLAARLRPNYPAALMNLGAILHLNGRLQKAEANYLRALQLKPDD 812
Cdd:COG0457 133 YERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAA 177
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 492-821 9.85e-15

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 78.59  E-value: 9.85e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   492 PAKAWGNLGNVLKSQSKISEAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIIL 571
Cdd:TIGR02917 600 SPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLL 679

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   572 MNQGKTEEARRTFlkcSEIPDENLKDPHAHKSsvtsclynLGKLYHEQGRYEEALSVYREAIQKmprhfAPQSLYNM-MG 650
Cdd:TIGR02917 680 LAAKRTESAKKIA---KSLQKQHPKAALGFEL--------EGDLYLRQKDYPAAIQAYRKALKR-----APSSQNAIkLH 743

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   651 EAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKFFLKAIELDPtkgncymhygqflleesrltea 730
Cdd:TIGR02917 744 RALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAP---------------------- 801

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   731 aemakkaaelDNTefdVVFNAAHMLRQASLNEAAEKYYDLAARLRPNYPAALMNLGAILHLNGRLQKAEANYLRALQLKP 810
Cdd:TIGR02917 802 ----------DNA---VVLNNLAWLYLELKDPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAP 868

                         330
                  ....*....|.
gi 50962841   811 DDVITQSNLRK 821
Cdd:TIGR02917 869 EAAAIRYHLAL 879
TPR_12 pfam13424
Tetratricopeptide repeat;
560-634 3.49e-09

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 53.93  E-value: 3.49e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 50962841   560 LASAYLNTGIILMNQGKTEEARRTFLKCSEIpDENLKDPHAHKSSVTscLYNLGKLYHEQGRYEEALSVYREAIQ 634
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEI-ARRLLGPDHPLTATT--LLNLGRLYLELGRYEEALELLERALA 73
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 510-675 2.19e-07

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 51.60  E-value: 2.19e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841  510 SEAESAYrnaLFYRSNMAdmlynlgllLQENSRFAEALHYYK--LAIGSRPTLASAYL-NTGIILMNQGKTEEARRTFLK 586
Cdd:PRK02603  30 KKAKEAF---VYYRDGMS---------AQADGEYAEALENYEeaLKLEEDPNDRSYILyNMGIIYASNGEHDKALEYYHQ 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841  587 CSEipdENLKDPhahkssvtSCLYNLGKLYHEQGRYEEALSVYREAiqkmprhfapQSLYNMMGEAYMRLSKL-P----E 661
Cdd:PRK02603  98 ALE---LNPKQP--------SALNNIAVIYHKRGEKAEEAGDQDEA----------EALFDKAAEYWKQAIRLaPnnyiE 156

                        170
                 ....*....|....
gi 50962841  662 AEHWYMESLRSKTD 675
Cdd:PRK02603 157 AQNWLKTTGRSNID 170
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 530-706 2.77e-06

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 49.93  E-value: 2.77e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 530 LYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGKTEEARRTFLKCSEIpdenlkDPHAhksSVTSCL 609
Cdd:cd24142   3 LLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIEL------DPDG---GYEKYL 73

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 610 YnLGKLyhEQGryEEALSVYREAIQKMPRHFAPQS------------LYNMMGEA-------YMR-LSKLPEAE---HWY 666
Cdd:cd24142  74 Y-LGQL--SGG--EEALQYYEKGIEILEEELQALQaasaeaeeeaeeLKRKLSSAlcalaeiYMTdLCDEPDAEqrcEEL 148

                       170       180       190       200
                ....*....|....*....|....*....|....*....|.
gi 50962841 667 MES-LRSKTDHIPAHLTYGKLLALTGRKSEAEKFFLKAIEL 706
Cdd:cd24142 149 ITKaLELDPTNPEALQTLASLRISQQRPDEAKEALRRSLEL 189
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 749-812 1.79e-05

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 43.09  E-value: 1.79e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 50962841   749 FNAAHMLRQASLNEAAEKYYDLAARLRPNYP---AALMNLGAILHLNGRLQKAEANYLRALQLKPDD 812
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFPESPdaaAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 611-811 2.68e-05

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 46.56  E-value: 2.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   611 NLGKLYHEQGRYEEALSVYREAIQKMPRHFAPqslYNMMGEAYMRLsklpeaehwymeslrsktdhipahltygkllalt 690
Cdd:TIGR02521  36 QLALGYLEQGDLEVAKENLDKALEHDPDDYLA---YLALALYYQQL---------------------------------- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   691 GRKSEAEKFFLKAIELDPTKGNCYMHYGQFLLEESRLteaaemakkaaeldntefdvvfnaahmlrqaslnEAAEKYYDL 770
Cdd:TIGR02521  79 GELEKAEDSFRRALTLNPNNGDVLNNYGTFLCQQGKY----------------------------------EQAMQQFEQ 124

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 50962841   771 AARLrPNYP---AALMNLGAILHLNGRLQKAEANYLRALQLKPD 811
Cdd:TIGR02521 125 AIED-PLYPqpaRSLENAGLCALKAGDFDKAEKYLTRALQIDPQ 167
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 608-639 3.14e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 41.66  E-value: 3.14e-05
                           10        20        30
                   ....*....|....*....|....*....|..
gi 50962841    608 CLYNLGKLYHEQGRYEEALSVYREAIQKMPRH 639
Cdd:smart00028   3 ALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 779-812 4.77e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 38.20  E-value: 4.77e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 50962841    779 PAALMNLGAILHLNGRLQKAEANYLRALQLKPDD 812
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 762-812 1.44e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 41.46  E-value: 1.44e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|.
gi 50962841 762 EAAEKYYDLAARLRPNYPAALMNLGAILHLNGRLQKAEANYLRALQLKPDD 812
Cdd:cd24142  17 ELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDG 67
ArnT COG1807
PMT family glycosyltransferase ArnT/Agl22, involved in glycosylation of proteins and lipid IVA ...
 78-198 5.65e-03

PMT family glycosyltransferase ArnT/Agl22, involved in glycosylation of proteins and lipid IVA [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441412 [Multi-domain]  Cd Length: 309  Bit Score: 39.61  E-value: 5.65e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841  78 AIGGLNPWSYHLVNVLLHAAVTGLFTRFSKALLGDGYWtFMAGLMFASHPIHteAVAGIVGRADVGASLFFLLSLLCYIk 157
Cdd:COG1807  77 KLFGVSEFAARLPSALLGLLTVLLVYLLARRLFGRRAA-LLAALLLLTSPLL--LLFGRLATPDALLLLFWTLALYALL- 152

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 50962841 158 hcstRGYSARTWGWFLGTGLCAGCSMLWKEQGVTVLAVSAV 198
Cdd:COG1807 153 ----RALERRRLRWLLLAGLALGLGFLTKGPVALLLPGLAL 189
 
Name Accession Description Interval E-value
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 247-321 2.87e-37

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


Pssm-ID: 462468  Cd Length: 75  Bit Score: 133.81  E-value: 2.87e-37
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 50962841   247 GNKPPSFSNSDNPAADSDSLLARTLTFLYLPTKNLWLLLCPDTLSFDWSMDAVPLLKTVCDWRNLHTVAFYSGLL 321
Cdd:pfam08409   1 GGQLPVFSASDNPAAFSPSLLTRTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYGALA 75
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
488-707 2.07e-29

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 117.42  E-value: 2.07e-29
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 488 IKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYL 565
Cdd:COG0457   1 LELDPddAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 566 NTGIILMNQGKTEEARRTFLKCSEIpdeNLKDPHAHkssvtsclYNLGKLYHEQGRYEEALSVYREAIQKMPRHfapQSL 645
Cdd:COG0457  81 NLGLALQALGRYEEALEDYDKALEL---DPDDAEAL--------YNLGLALLELGRYDEAIEAYERALELDPDD---ADA 146

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 50962841 646 YNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKFFLKAIELD 707
Cdd:COG0457 147 LYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALR 208
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 511-807 1.03e-27

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 113.29  E-value: 1.03e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 511 EAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGKTEEARRTFLKCSEI 590
Cdd:COG2956  26 KAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLEL 105

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 591 PDENLkdphahkssvtSCLYNLGKLYHEQGRYEEALSVYREAIQKMPRHFApqsLYNMMGEAYMRLSKLPEAEHWYMESL 670
Cdd:COG2956 106 DPDDA-----------EALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAH---AYCELAELYLEQGDYDEAIEALEKAL 171

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 671 RSKTDHIPAHLTYGKLLALTGRKSEAEKFFLKAIELDPTKGNCYMHYGQFLLEESRLteaaemakkaaeldntefdvvfn 750
Cdd:COG2956 172 KLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDP----------------------- 228

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 50962841 751 aahmlrqaslnEAAEKYYDLAARLRPNyPAALMNLGAILHLNGRLQKAEANYLRALQ 807
Cdd:COG2956 229 -----------EEALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLERQLR 273
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 560-812 7.26e-27

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 110.97  E-value: 7.26e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 560 LASAYLNTGIILMNQGKTEEARRTFLKCSEIPDENLKdphAHkssvtsclYNLGKLYHEQGRYEEALSVYREAIQKMPRH 639
Cdd:COG2956   7 AALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVE---AH--------LALGNLYRRRGEYDRAIRIHQKLLERDPDR 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 640 FApqsLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKFFLKAIELDPTKGNCYMHYGQ 719
Cdd:COG2956  76 AE---ALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAE 152

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 720 FLLEESRLTEAAEMAKKAAELDNTEFDVVFNAAHMLRQASLNEAAEKYYDLAARLRPNYPAALMNLGAILHLNGRLQKAE 799
Cdd:COG2956 153 LYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEAL 232

                       250
                ....*....|...
gi 50962841 800 ANYLRALQLKPDD 812
Cdd:COG2956 233 ELLRKALELDPSD 245
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 473-707 1.00e-26

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 110.59  E-value: 1.00e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 473 RNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALHYY 550
Cdd:COG2956  54 RRGEYDRAIRIHQKLLERDPdrAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVL 133

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 551 KLAIGSRPTLASAYLNTGIILMNQGKTEEARRTFLKCSEIpdenlkDPHAHKSsvtscLYNLGKLYHEQGRYEEALSVYR 630
Cdd:COG2956 134 ERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKL------DPDCARA-----LLLLAELYLEQGDYEEAIAALE 202

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 50962841 631 EAIQKMPRHFapqSLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDhIPAHLTYGKLLALTGRKSEAEKFFLKAIELD 707
Cdd:COG2956 203 RALEQDPDYL---PALPRLAELYEKLGDPEEALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLERQLRRH 275
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 471-708 1.01e-26

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 110.59  E-value: 1.01e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 471 AIRNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALH 548
Cdd:COG2956  18 YLLNGQPDKAIDLLEEALELDPetVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEE 97

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 549 YYKLAIGSRPTLASAYLNTGIILMNQGKTEEARRTFLKCSEIPDENlkdPHAHkssvtsclYNLGKLYHEQGRYEEALSV 628
Cdd:COG2956  98 LLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPEN---AHAY--------CELAELYLEQGDYDEAIEA 166

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 629 YREAIQKMPRHFAPqslYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKFFLKAIELDP 708
Cdd:COG2956 167 LEKALKLDPDCARA---LLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDP 243
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
558-809 2.38e-26

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 108.56  E-value: 2.38e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 558 PTLASAYLNTGIILMNQGKTEEARRTFLKCSEIpdenlkDPHAHKSsvtscLYNLGKLYHEQGRYEEALSVYREAIQKMP 637
Cdd:COG0457   5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL------DPDDAEA-----LYNLGLAYLRLGRYEEALADYEQALELDP 73

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 638 RHFApqsLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKFFLKAIELDPTKGNCYMHY 717
Cdd:COG0457  74 DDAE---ALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNL 150

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 718 GQFLLEESRLTEAAEMAKKAAELDNTEFDVVFNAAHMLRQASLNEAAEKYYDLAARLRPNYPAALMNLGAILHLNGRLQK 797
Cdd:COG0457 151 GIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALL 230

                       250
                ....*....|..
gi 50962841 798 AEANYLRALQLK 809
Cdd:COG0457 231 LALRLAALALYQ 242
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
608-812 2.14e-25

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 105.86  E-value: 2.14e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 608 CLYNLGKLYHEQGRYEEALSVYREAIQKMPRHfaPQSLYNMmGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLL 687
Cdd:COG0457  10 AYNNLGLAYRRLGRYEEAIEDYEKALELDPDD--AEALYNL-GLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLAL 86

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 688 ALTGRKSEAEKFFLKAIELDPTKGNCYMHYGQFLLEESRLteaaemakkaaeldntefdvvfnaahmlrqaslnEAAEKY 767
Cdd:COG0457  87 QALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRY----------------------------------DEAIEA 132

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*
gi 50962841 768 YDLAARLRPNYPAALMNLGAILHLNGRLQKAEANYLRALQLKPDD 812
Cdd:COG0457 133 YERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAA 177
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 511-795 4.41e-23

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 105.08  E-value: 4.41e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 511 EAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGKTEEARRTFLKCSEI 590
Cdd:COG3914  28 LAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALAL 107

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 591 pdenlkDPHAHKSsvtscLYNLGKLYHEQGRYEEALSVYREAIQKMPRHFApqsLYNMMGEAYMRLSKLPEAEHWYMESL 670
Cdd:COG3914 108 ------NPDNAEA-----LFNLGNLLLALGRLEEALAALRRALALNPDFAE---AYLNLGEALRRLGRLEEAIAALRRAL 173

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 671 RSKTDHIPAHLTYGKLLALTGRKSEAEKFFLKAIELDPTKGNCYMHYGQFLLEESRLTEAAEMAKKAAELDNTEFDVVFN 750
Cdd:COG3914 174 ELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSELSPF 253

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*
gi 50962841 751 AAHMLRQASLNEAAEKYYDLAARLRPNYPAALMNLGAILHLNGRL 795
Cdd:COG3914 254 ALLYLPDDDPAELLALARAWAQLVAAAAAPELPPPPNPRDPDRKL 298
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 499-646 1.24e-21

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 100.45  E-value: 1.24e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 499 LGNVLKSQSKISEAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGKTE 578
Cdd:COG3914  84 AALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLE 163

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 50962841 579 EARRTFLKCSEI-PDenlkDPHAHkssvtsclYNLGKLYHEQGRYEEALSVYREAIQKMPRHFAPQSLY 646
Cdd:COG3914 164 EAIAALRRALELdPD----NAEAL--------NNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 472-671 1.97e-21

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 95.18  E-value: 1.97e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 472 IRNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALHY 549
Cdd:COG2956  87 LKAGLLDRAEELLEKLLELDPddAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEA 166

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 550 YKLAIGSRPTLASAYLNTGIILMNQGKTEEARRTFLKCSEIpdenlkDPHAhkssvTSCLYNLGKLYHEQGRYEEALSVY 629
Cdd:COG2956 167 LEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQ------DPDY-----LPALPRLAELYEKLGDPEEALELL 235

                       170       180       190       200
                ....*....|....*....|....*....|....*....|..
gi 50962841 630 REAIQKMPRHfapqSLYNMMGEAYMRLSKLPEAEHWYMESLR 671
Cdd:COG2956 236 RKALELDPSD----DLLLALADLLERKEGLEAALALLERQLR 273
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 473-596 4.23e-21

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 98.53  E-value: 4.23e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 473 RNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALHYY 550
Cdd:COG3914  90 ALGRYEEALALYRRALALNPdnAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAAL 169

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*.
gi 50962841 551 KLAIGSRPTLASAYLNTGIILMNQGKTEEARRTFLKCSEIPDENLK 596
Cdd:COG3914 170 RRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNAD 215
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 561-708 1.93e-20

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 88.33  E-value: 1.93e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 561 ASAYLNTGIILMNQGKTEEARRTFLKCSEIPDENlkdPHAhkssvtscLYNLGKLYHEQGRYEEALSVYREAIQKMPRHF 640
Cdd:COG4783   4 AEALYALAQALLLAGDYDEAEALLEKALELDPDN---PEA--------FALLGEILLQLGDLDEAIVLLHEALELDPDEP 72

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 50962841 641 ApqsLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKFFLKAIELDP 708
Cdd:COG4783  73 E---ARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 532-785 8.28e-20

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 94.67  E-value: 8.28e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 532 NLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGKTEEARRTFLkcSEIPDENLKDPHAHKSSVTSCLYN 611
Cdd:COG3914   6 LLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAAL--LALAAGEAAAAAAALLLLAALLEL 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 612 LGKLYHEQGRYEEALSVYREAIQKMPRHFApqsLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTG 691
Cdd:COG3914  84 AALLLQALGRYEEALALYRRALALNPDNAE---ALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLG 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 692 RKSEAEKFFLKAIELDPtkgncymhygqflleesrlteaaemakkaaelDNTEfdVVFNAAHMLRQASLNEAAEKYYDLA 771
Cdd:COG3914 161 RLEEAIAALRRALELDP--------------------------------DNAE--ALNNLGNALQDLGRLEEAIAAYRRA 206

                       250
                ....*....|....
gi 50962841 772 ARLRPNYPAALMNL 785
Cdd:COG3914 207 LELDPDNADAHSNL 220
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 524-676 2.51e-19

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 84.86  E-value: 2.51e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 524 SNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGKTEEARRTFLKCSEI-PDEnlkdPHAHk 602
Cdd:COG4783   1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELdPDE----PEAR- 75

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 50962841 603 ssvtsclYNLGKLYHEQGRYEEALSVYREAIQKMPRHfaPQSLYNmMGEAYMRLSKLPEAEHWYMESLRSKTDH 676
Cdd:COG4783  76 -------LNLGLALLKAGDYDEALALLEKALKLDPEH--PEAYLR-LARAYRALGRPDEAIAALEKALELDPDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 641-812 2.00e-17

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 79.47  E-value: 2.00e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 641 APQSLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKFFLKAIELDPTkgncymhygqf 720
Cdd:COG4783   2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPD----------- 70

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 721 lleesrlteaaemakkaaeldntEFDVVFNAAHMLRQASLNEAAEKYYDLAARLRPNYPAALMNLGAILHLNGRLQKAEA 800
Cdd:COG4783  71 -----------------------EPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIA 127

                       170
                ....*....|..
gi 50962841 801 NYLRALQLKPDD 812
Cdd:COG4783 128 ALEKALELDPDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 609-727 2.23e-16

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 76.77  E-value: 2.23e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 609 LYNLGKLYHEQGRYEEALSVYREAIQKMPRHFApqsLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLA 688
Cdd:COG4783   7 LYALAQALLLAGDYDEAEALLEKALELDPDNPE---AFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                        90       100       110
                ....*....|....*....|....*....|....*....
gi 50962841 689 LTGRKSEAEKFFLKAIELDPTKGNCYMHYGQFLLEESRL 727
Cdd:COG4783  84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRP 122
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
670-819 3.62e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.90  E-value: 3.62e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 670 LRSKTDHIPAHLTYGKLLALTGRKSEAEKFFLKAIELDPTKGNCYMHYGQFLLEESRLTEAAEMAKKAAELDNTEFDVVF 749
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 750 NAAHMLRQASLNEAAEKYYDLAARLRPNYPAALMNLGAILHLNGRLQKAEANYLRALQLKPDDVITQSNL 819
Cdd:COG0457  81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNL 150
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 493-639 3.98e-16

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 76.00  E-value: 3.98e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 493 AKAWGNLGNVLKSQSKISEAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILM 572
Cdd:COG4783   4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 50962841 573 NQGKTEEARRTFLKCSEIpdeNLKDPHAHkssvtsclYNLGKLYHEQGRYEEALSVYREAIQKMPRH 639
Cdd:COG4783  84 KAGDYDEALALLEKALKL---DPEHPEAY--------LRLARAYRALGRPDEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 511-652 2.67e-15

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 73.12  E-value: 2.67e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 511 EAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGKTEEARRTFLKCSEI 590
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 50962841 591 pdenlkDPHAHKSsvtscLYNLGKLYHEQGRYEEALSVYREAIQKMPRHFAPQSLYNMMGEA 652
Cdd:COG4235  81 ------DPDNPEA-----LYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASIAEA 131
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 492-821 9.85e-15

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 78.59  E-value: 9.85e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   492 PAKAWGNLGNVLKSQSKISEAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIIL 571
Cdd:TIGR02917 600 SPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLL 679

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   572 MNQGKTEEARRTFlkcSEIPDENLKDPHAHKSsvtsclynLGKLYHEQGRYEEALSVYREAIQKmprhfAPQSLYNM-MG 650
Cdd:TIGR02917 680 LAAKRTESAKKIA---KSLQKQHPKAALGFEL--------EGDLYLRQKDYPAAIQAYRKALKR-----APSSQNAIkLH 743

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   651 EAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKFFLKAIELDPtkgncymhygqflleesrltea 730
Cdd:TIGR02917 744 RALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAP---------------------- 801

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   731 aemakkaaelDNTefdVVFNAAHMLRQASLNEAAEKYYDLAARLRPNYPAALMNLGAILHLNGRLQKAEANYLRALQLKP 810
Cdd:TIGR02917 802 ----------DNA---VVLNNLAWLYLELKDPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAP 868

                         330
                  ....*....|.
gi 50962841   811 DDVITQSNLRK 821
Cdd:TIGR02917 869 EAAAIRYHLAL 879
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 615-708 2.73e-14

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 71.14  E-value: 2.73e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 615 LYHEQGRYEEALSVYREAIQKMPRHFApqsLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKS 694
Cdd:COG5010  63 LYNKLGDFEESLALLEQALQLDPNNPE---LYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDD 139

                        90
                ....*....|....
gi 50962841 695 EAEKFFLKAIELDP 708
Cdd:COG5010 140 EAKAALQRALGTSP 153
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
493-634 1.79e-13

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 70.71  E-value: 1.79e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 493 AKAWGNLGNVLKSQSKISEAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILM 572
Cdd:COG4785  73 AQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALY 152

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 50962841 573 NQGKTEEARRTFLKCSEIPDEN------------LKDPHAHKSSVTSclyNLGKLYHEQGRYEEALSVYREAIQ 634
Cdd:COG4785 153 YLGRYELAIADLEKALELDPNDperalwlylaerKLDPEKALALLLE---DWATAYLLQGDTEEARELFKLALA 223
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 469-594 2.23e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 67.91  E-value: 2.23e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 469 KTAIRNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEA 546
Cdd:COG4783  12 QALLLAGDYDEAEALLEKALELDPdnPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEA 91

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 50962841 547 LHYYKLAIGSRPTLASAYLNTGIILMNQGKTEEARRTFLKCSEIPDEN 594
Cdd:COG4783  92 LALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 470-582 3.41e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 73.49  E-value: 3.41e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 470 TAIRNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEAL 547
Cdd:COG3914 121 LLLALGRLEEALAALRRALALNPdfAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAI 200

                        90       100       110
                ....*....|....*....|....*....|....*
gi 50962841 548 HYYKLAIGSRPTLASAYLNTGIILMNQGKTEEARR 582
Cdd:COG3914 201 AAYRRALELDPDNADAHSNLLFALRQACDWEVYDR 235
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 519-824 5.45e-13

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 72.81  E-value: 5.45e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   519 ALFYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGKTEEARRTFLKCSEIPDENlkdP 598
Cdd:TIGR02917 355 ALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPEL---G 431

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   599 HAHKSSVTSclynlgklYHEQGRYEEALSVYREAIQKMPrhfAPQSLYNMMGEAYMRLSKLPEAEHWYMESLRSKTD--- 675
Cdd:TIGR02917 432 RADLLLILS--------YLRSGQFDKALAAAKKLEKKQP---DNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDffp 500

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   676 -------------------------------HIPAHLTYGKLLALTGRKSEAEKFFLKAIELDPTKGNCYMHYGQFLLEE 724
Cdd:TIGR02917 501 aaanlaridiqegnpddaiqrfekvltidpkNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGK 580

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   725 SRLTEAAEMAKKAAEL--DNTEFDVVFNAAHmLRQASLNEAAEKYYDLAARLrPNYPAALMNLGAILHLNGRLQKAEANY 802
Cdd:TIGR02917 581 GQLKKALAILNEAADAapDSPEAWLMLGRAQ-LAAGDLNKAVSSFKKLLALQ-PDSALALLLLADAYAVMKNYAKAITSL 658

                         330       340
                  ....*....|....*....|..
gi 50962841   803 LRALQLKPDDVITQSNLRKLWN 824
Cdd:TIGR02917 659 KRALELKPDNTEAQIGLAQLLL 680
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 492-822 9.25e-13

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 72.04  E-value: 9.25e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   492 PAKAWGNLGNVLKSQSKISEAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIIL 571
Cdd:TIGR02917 192 NVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVD 271

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   572 MNQGKTEEARRTFLKCSEIPDENLkdphahkssvtSCLYNLGKLYHEQGRYEEALSVYREAIQkmprhFAPQSLY--NMM 649
Cdd:TIGR02917 272 FQKKNYEDARETLQDALKSAPEYL-----------PALLLAGASEYQLGNLEQAYQYLNQILK-----YAPNSHQarRLL 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   650 GEAYMRLSKlpeaehwYMESLRSKTDHIPAHLTYGKLLALTGRK-------SEAEKFFLKAIELDPTKGNCYMHYGQFLL 722
Cdd:TIGR02917 336 ASIQLRLGR-------VDEAIATLSPALGLDPDDPAALSLLGEAylalgdfEKAAEYLAKATELDPENAAARTQLGISKL 408

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   723 EESRLTEAAEMAKKAAELDNTEFDV-VFNAAHMLRQASLNEAAEkyydLAARLRPNYP--AALMNL-GAILHLNGRLQKA 798
Cdd:TIGR02917 409 SQGDPSEAIADLETAAQLDPELGRAdLLLILSYLRSGQFDKALA----AAKKLEKKQPdnASLHNLlGAIYLGKGDLAKA 484

                         330       340
                  ....*....|....*....|....
gi 50962841   799 EANYLRALQLKPDDVITQSNLRKL 822
Cdd:TIGR02917 485 REAFEKALSIEPDFFPAAANLARI 508
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
615-708 9.75e-13

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 64.81  E-value: 9.75e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 615 LYHEQGRYEEALSVYREAIQKMPRHFApqsLYNMMGEAYMRLSKLPEAEHwYMESLRSKTDHIPAHLTYGKLLALTGRKS 694
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNAD---ALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYD 76

                        90
                ....*....|....
gi 50962841 695 EAEKFFLKAIELDP 708
Cdd:COG3063  77 EALAYLERALELDP 90
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 511-637 2.95e-12

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 65.37  E-value: 2.95e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 511 EAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGKTEEARRTFLKCSEI 590
Cdd:COG5010  38 KEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALAL 117

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 50962841 591 PDENlkdPHAHkssvtsclYNLGKLYHEQGRYEEALSVYREAIQKMP 637
Cdd:COG5010 118 SPDN---PNAY--------SNLAALLLSLGQDDEAKAALQRALGTSP 153
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 661-812 4.25e-12

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 63.87  E-value: 4.25e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 661 EAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKFFLKAIELDPtkgncymhygqflleesrlteaaemakkaael 740
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDP-------------------------------- 48

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 50962841 741 DNTefDVVFNAAHMLRQASLNEAAEKYYDLAARLRPNYPAALMNLGAILHLNGRLQKAEANYLRALQLKPDD 812
Cdd:COG4235  49 DNA--DALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 470-835 5.47e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 69.73  E-value: 5.47e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   470 TAIRNGDWQNEEMLYRSGIKVNPAKA--WGNLGNVLKSQSKISEAESAYRNAL-------FYRSNMADMLYNLGLLLQEN 540
Cdd:TIGR02917 440 SYLRSGQFDKALAAAKKLEKKQPDNAslHNLLGAIYLGKGDLAKAREAFEKALsiepdffPAAANLARIDIQEGNPDDAI 519

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   541 SRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGKTEEARRtflkcseipdenlKDPHAHKSSVtsclyNLGKLYHEQG 620
Cdd:TIGR02917 520 QRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAE-------------LNPQEIEPAL-----ALAQYYLGKG 581

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   621 RYEEALSVYREAIQKMPRHfapQSLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKFF 700
Cdd:TIGR02917 582 QLKKALAILNEAADAAPDS---PEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSL 658

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   701 LKAIELDPTKGNCYMHYGQFLLEESRLTEAAEMAKKA-AELDNTEFDVVFNAAHMLRQASLnEAAEKYYDLAARLRPNyP 779
Cdd:TIGR02917 659 KRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLqKQHPKAALGFELEGDLYLRQKDY-PAAIQAYRKALKRAPS-S 736

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 50962841   780 AALMNLGAILHLNGRLQKAEANYLRALQLKPDDVITQSNLRKLWnIMEKQGLKTSK 835
Cdd:TIGR02917 737 QNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELY-LAQKDYDKAIK 791
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
536-638 7.12e-12

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 62.11  E-value: 7.12e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 536 LLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGKTEEARRtFLKCSEIpdeNLKDPHAhkssvtscLYNLGKL 615
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKL---DPNNAEA--------LLNLAEL 68

                        90       100
                ....*....|....*....|...
gi 50962841 616 YHEQGRYEEALSVYREAIQKMPR 638
Cdd:COG3063  69 LLELGDYDEALAYLERALELDPS 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 440-586 8.51e-12

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 63.83  E-value: 8.51e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 440 RALYVKVQKRFLKSLVFYATATLIVFYGVKTAIRNGDWQNEEMLYRSGIKVNPAKAWGNLGNVLKSQSKISEAESAYRNA 519
Cdd:COG5010   1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 50962841 520 LFYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGKTEEARRTFLK 586
Cdd:COG5010  81 LQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQR 147
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 512-672 1.46e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 63.44  E-value: 1.46e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 512 AESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGKTEEARRTFLKCSEIp 591
Cdd:COG5010   5 EGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL- 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 592 deNLKDPHAHkssvtsclYNLGKLYHEQGRYEEALSVYREAIQKMPRHfaPQSLYNmMGEAYMRLSKLPEAEHWYMESLR 671
Cdd:COG5010  84 --DPNNPELY--------YNLALLYSRSGDKDEAKEYYEKALALSPDN--PNAYSN-LAALLLSLGQDDEAKAALQRALG 150


                .
gi 50962841 672 S 672
Cdd:COG5010 151 T 151
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 484-594 3.00e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 61.56  E-value: 3.00e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 484 YRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLA 561
Cdd:COG4235   6 LRQALAANPndAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                        90       100       110
                ....*....|....*....|....*....|...
gi 50962841 562 SAYLNTGIILMNQGKTEEARRTFLKCSEIPDEN 594
Cdd:COG4235  86 EALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 714-819 6.60e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 61.51  E-value: 6.60e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 714 YMHYGQFLLEESRLTEAAEMAKKAAELDNTEFDVVFNAAHMLRQaslNEAAEKYYDLAARLRPNYPAALMNLGAILHLNG 793
Cdd:COG5010  26 KYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGD---FEESLALLEQALQLDPNNPELYYNLALLYSRSG 102

                        90       100
                ....*....|....*....|....*.
gi 50962841 794 RLQKAEANYLRALQLKPDDVITQSNL 819
Cdd:COG5010 103 DKDEAKEYYEKALALSPDNPNAYSNL 128
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
502-596 6.83e-11

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 59.41  E-value: 6.83e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 502 VLKSQSKISEAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALHYYKlAIGSRPTLASAYLNTGIILMNQGKTEEAR 581
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEK-ALKLDPNNAEALLNLAELLLELGDYDEAL 79

                        90
                ....*....|....*
gi 50962841 582 RTFLKCSEIPDENLK 596
Cdd:COG3063  80 AYLERALELDPSALR 94
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
512-705 1.17e-10

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 62.24  E-value: 1.17e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 512 AESAYRNALFYRsNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGKTEEARRTFLKCSEI- 590
Cdd:COG4785  59 AAERIDRALALP-DLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELd 137

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 591 PDenlkDPHAHkssvtsclYNLGKLYHEQGRYEEALSVYREAIQKMPrhfapqslynmmgeaymrlsKLPEAEHW-YMES 669
Cdd:COG4785 138 PD----YAYAY--------LNRGIALYYLGRYELAIADLEKALELDP--------------------NDPERALWlYLAE 185

                       170       180       190
                ....*....|....*....|....*....|....*...
gi 50962841 670 LRSKTDHIPAHLT--YGKLLALTGRKSEAEKFFLKAIE 705
Cdd:COG4785 186 RKLDPEKALALLLedWATAYLLQGDTEEARELFKLALA 223
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 651-810 4.26e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 59.20  E-value: 4.26e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 651 EAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKFFLKAIELDPTKGNCYMHYGQFLLEESRLtea 730
Cdd:COG5010  28 EAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDK--- 104

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 731 aemakkaaeldntefdvvfnaahmlrqaslnEAAEKYYDLAARLRPNYPAALMNLGAILHLNGRLQKAEANYLRALQLKP 810
Cdd:COG5010 105 -------------------------------DEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 614-708 4.94e-10

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 57.69  E-value: 4.94e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 614 KLYHEQGRYEEALSVYREAIQKMPRH-FAPQSLYnMMGEAYMRLSKLPEAEHWYMESLRSKTDHIP---AHLTYGKLLAL 689
Cdd:COG1729   1 KALLKAGDYDEAIAAFKAFLKRYPNSpLAPDALY-WLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLE 79

                        90
                ....*....|....*....
gi 50962841 690 TGRKSEAEKFFLKAIELDP 708
Cdd:COG1729  80 LGDYDKARATLEELIKKYP 98
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
686-811 6.06e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 56.72  E-value: 6.06e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 686 LLALTGRKSEAEKFFLKAIELDPTKGNCYMHYGQFLLEESRLteaaemakkaaeldntefdvvfnaahmlrqaslnEAAE 765
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRY----------------------------------DEAI 46

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*.
gi 50962841 766 KYyDLAARLRPNYPAALMNLGAILHLNGRLQKAEANYLRALQLKPD 811
Cdd:COG3063  47 AL-EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPS 91
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 569-668 6.68e-10

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 57.31  E-value: 6.68e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 569 IILMNQGKTEEARRTFLK-CSEIPDENLKDphahkssvtSCLYNLGKLYHEQGRYEEALSVYREAIQKMPRH-FAPQSLY 646
Cdd:COG1729   1 KALLKAGDYDEAIAAFKAfLKRYPNSPLAP---------DALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSpKAPDALL 71

                        90       100
                ....*....|....*....|..
gi 50962841 647 nMMGEAYMRLSKLPEAEHWYME 668
Cdd:COG1729  72 -KLGLSYLELGDYDKARATLEE 92
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 678-822 2.01e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 56.74  E-value: 2.01e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 678 PAHLTYGKLLALTGRKSEAEKFFLKAIELDPTkgncymhygqflleesrlteaaemakkaaeldntEFDVVFNAAHMLRQ 757
Cdd:COG4783   5 EALYALAQALLLAGDYDEAEALLEKALELDPD----------------------------------NPEAFALLGEILLQ 50

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 50962841 758 ASLNEAAEKYYDLAARLRPNYPAALMNLGAILHLNGRLQKAEANYLRALQLKPDDVITQSNLRKL 822
Cdd:COG4783  51 LGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARA 115
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
755-819 2.11e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 55.18  E-value: 2.11e-09
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 50962841 755 LRQASLNEAAEKYYDLAARLRPNYPAALMNLGAILHLNGRLQKAEAnYLRALQLKPDDVITQSNL 819
Cdd:COG3063   2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNL 65
TPR_12 pfam13424
Tetratricopeptide repeat;
560-634 3.49e-09

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 53.93  E-value: 3.49e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 50962841   560 LASAYLNTGIILMNQGKTEEARRTFLKCSEIpDENLKDPHAHKSSVTscLYNLGKLYHEQGRYEEALSVYREAIQ 634
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEI-ARRLLGPDHPLTATT--LLNLGRLYLELGRYEEALELLERALA 73
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
471-560 3.64e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 54.41  E-value: 3.64e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 471 AIRNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAEsAYRNALFYRSNMADMLYNLGLLLQENSRFAEALH 548
Cdd:COG3063   2 YLKLGDLEEAEEYYEKALELDPdnADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEALA 80

                        90
                ....*....|..
gi 50962841 549 YYKLAIGSRPTL 560
Cdd:COG3063  81 YLERALELDPSA 92
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 539-639 4.75e-09

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 54.61  E-value: 4.75e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 539 ENSRFAEALHYYKLAIGSRPT---LASAYLNTGIILMNQGKTEEARRTFLKCSEIPDENLKDPHAhkssvtscLYNLGKL 615
Cdd:COG1729   5 KAGDYDEAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDA--------LLKLGLS 76

                        90       100
                ....*....|....*....|....
gi 50962841 616 YHEQGRYEEALSVYREAIQKMPRH 639
Cdd:COG1729  77 YLELGDYDKARATLEELIKKYPDS 100
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 470-717 5.06e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 60.10  E-value: 5.06e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   470 TAIRNGDWQNEEMLYRSGIKVNPAK--AWGNLGNVLKSQSKISEAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEAL 547
Cdd:TIGR02917 610 AQLAAGDLNKAVSSFKKLLALQPDSalALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAK 689

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   548 HYYKLAIGSRPTLASAYLNTGIILMNQGKTEEAR---RTFLKCSEIPDENLKDPHAH---------------------KS 603
Cdd:TIGR02917 690 KIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIqayRKALKRAPSSQNAIKLHRALlasgntaeavktleawlkthpND 769

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   604 SVTscLYNLGKLYHEQGRYEEALSVYREAIQKMPRHfaPQSLYNMmgeAYMRL-SKLPEAEHWYMESLRSKtDHIPAHL- 681
Cdd:TIGR02917 770 AVL--RTALAELYLAQKDYDKAIKHYQTVVKKAPDN--AVVLNNL---AWLYLeLKDPRALEYAERALKLA-PNIPAILd 841

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 50962841   682 TYGKLLALTGRKSEAEKFFLKAIELDPTKGNCYMHY 717
Cdd:TIGR02917 842 TLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHL 877
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 609-727 7.22e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 55.35  E-value: 7.22e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 609 LYNLGKLYHEQGRYEEALSVYREAIQKMPRHFAPQSLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLA 688
Cdd:COG5010  20 LRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYS 99

                        90       100       110
                ....*....|....*....|....*....|....*....
gi 50962841 689 LTGRKSEAEKFFLKAIELDPTKGNCYMHYGQFLLEESRL 727
Cdd:COG5010 100 RSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQD 138
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
652-727 1.84e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 52.48  E-value: 1.84e-08
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 50962841 652 AYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKfFLKAIELDPTKGNCYMHYGQFLLEESRL 727
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDY 75
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 439-558 2.03e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 54.20  E-value: 2.03e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 439 ARALYVKVQKRFLKSLVFYATATLIVFYGVKTAIRNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAY 516
Cdd:COG5010  32 AGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPnnPELYYNLALLYSRSGDKDEAKEYY 111

                        90       100       110       120
                ....*....|....*....|....*....|....*....|..
gi 50962841 517 RNALFYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRP 558
Cdd:COG5010 112 EKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
611-813 2.92e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 55.31  E-value: 2.92e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 611 NLGKLYHEQGRYEEALSVYREAIQKMPRHFAPQSLYNMMGEAYMRLSKLPEAEHWYMESLR---SKTDHIPAHLTYGKLL 687
Cdd:COG4785   4 LALALLLALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDralALPDLAQLYYERGVAY 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 688 ALTGRKSEAEKFFLKAIELDPTKGNCYMHYGqflleesrlteaaemakkaaeldntefdvvfnAAHMLRQAslNEAAEKY 767
Cdd:COG4785  84 DSLGDYDLAIADFDQALELDPDLAEAYNNRG--------------------------------LAYLLLGD--YDAALED 129

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*.
gi 50962841 768 YDLAARLRPNYPAALMNLGAILHLNGRLQKAEANYLRALQLKPDDV 813
Cdd:COG4785 130 FDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDP 175
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 752-819 7.00e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.93  E-value: 7.00e-08
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 50962841 752 AHMLRQASLNEAAEKYYDLAARLRPNYPAALMNLGAILHLNGRLQKAEANYLRALQLKPDDVITQSNL 819
Cdd:COG4235  24 GRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLL 91
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
749-819 2.07e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 52.61  E-value: 2.07e-07
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 50962841 749 FNAAHMLRQASLNEAAEKYYDLAARLRPNYPAALMNLGAILHLNGRLQKAEANYLRALQLKPDDVITQSNL 819
Cdd:COG4785  77 YERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNR 147
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 510-675 2.19e-07

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 51.60  E-value: 2.19e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841  510 SEAESAYrnaLFYRSNMAdmlynlgllLQENSRFAEALHYYK--LAIGSRPTLASAYL-NTGIILMNQGKTEEARRTFLK 586
Cdd:PRK02603  30 KKAKEAF---VYYRDGMS---------AQADGEYAEALENYEeaLKLEEDPNDRSYILyNMGIIYASNGEHDKALEYYHQ 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841  587 CSEipdENLKDPhahkssvtSCLYNLGKLYHEQGRYEEALSVYREAiqkmprhfapQSLYNMMGEAYMRLSKL-P----E 661
Cdd:PRK02603  98 ALE---LNPKQP--------SALNNIAVIYHKRGEKAEEAGDQDEA----------EALFDKAAEYWKQAIRLaPnnyiE 156

                        170
                 ....*....|....
gi 50962841  662 AEHWYMESLRSKTD 675
Cdd:PRK02603 157 AQNWLKTTGRSNID 170
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 746-830 3.13e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 50.19  E-value: 3.13e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 746 DVVFNAAHMLRQASLNEAAEKYYDLAARLRPNYPAALMNLGAILHLNGRLQKAEANYLRALQLKPDDVITQSNlrkLWNI 825
Cdd:COG4783   5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLN---LGLA 81


                ....*
gi 50962841 826 MEKQG 830
Cdd:COG4783  82 LLKAG 86
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 545-775 3.88e-07

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 53.83  E-value: 3.88e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   545 EALHYYKLAIGSRPTLASAYLNTGIILMNQGKTEEARRTFLKCSEIPDENLKdPHAHkssvtsclynLGKLYHEQGRYEE 624
Cdd:TIGR00990 383 KAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIF-SHIQ----------LGVTQYKEGSIAS 451

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   625 ALSVYREAIQKMPRhfAPQsLYNMMGEAYMRLSKLPEAEHWYMES--LRSKTDHIPAHLT--YGKLLALTGRK---SEAE 697
Cdd:TIGR00990 452 SMATFRRCKKNFPE--APD-VYNYYGELLLDQNKFDEAIEKFDTAieLEKETKPMYMNVLplINKALALFQWKqdfIEAE 528

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   698 KFFLKAIELDPTKGNCYMHYGQFLLEESRLTEAAEMAKKAAELDNTEfdvvfnaAHMLRQASLNEAA-------EKYYDL 770
Cdd:TIGR00990 529 NLCEKALIIDPECDIAVATMAQLLLQQGDVDEALKLFERAAELARTE-------GELVQAISYAEATrtqiqvqEDYPVL 601


                  ....*
gi 50962841   771 AARLR 775
Cdd:TIGR00990 602 ASKLQ 606
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 530-706 2.77e-06

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 49.93  E-value: 2.77e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 530 LYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGKTEEARRTFLKCSEIpdenlkDPHAhksSVTSCL 609
Cdd:cd24142   3 LLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIEL------DPDG---GYEKYL 73

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 610 YnLGKLyhEQGryEEALSVYREAIQKMPRHFAPQS------------LYNMMGEA-------YMR-LSKLPEAE---HWY 666
Cdd:cd24142  74 Y-LGQL--SGG--EEALQYYEKGIEILEEELQALQaasaeaeeeaeeLKRKLSSAlcalaeiYMTdLCDEPDAEqrcEEL 148

                       170       180       190       200
                ....*....|....*....|....*....|....*....|.
gi 50962841 667 MES-LRSKTDHIPAHLTYGKLLALTGRKSEAEKFFLKAIEL 706
Cdd:cd24142 149 ITKaLELDPTNPEALQTLASLRISQQRPDEAKEALRRSLEL 189
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 506-584 4.05e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 46.52  E-value: 4.05e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 506 QSKISEAESAYRNAL--FYRSNMA-DMLYNLGLLLQENSRFAEALHYYKLAIGSRPT---LASAYLNTGIILMNQGKTEE 579
Cdd:COG1729   6 AGDYDEAIAAFKAFLkrYPNSPLApDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYLELGDYDK 85


                ....*
gi 50962841 580 ARRTF 584
Cdd:COG1729  86 ARATL 90
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
481-700 5.03e-06

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 48.72  E-value: 5.03e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 481 EMLYRSGIKVNPAKAWGNLGNVLKSQSKISEAESAYRNalfyrsnmADMLYNlglllqensrfaealhyyklaigsRPTL 560
Cdd:COG4700  48 EVLPELRNSRDARRVQRAARNALDPGRELRELEKALEF--------ADTVQN------------------------RVRL 95

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 561 ASAYLntgiilmNQGKTEEARRTFLKCseipdenLKDPHAHKSSVtscLYNLGKLYHEQGRYEEALSVYREAIQKMPRHF 640
Cdd:COG4700  96 ADALL-------ELGRYDEAIELYEEA-------LTGIFADDPHI---LLGLAQALFELGRYAEALETLEKLIAKNPDFK 158

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 50962841 641 APQS--LYnmmGEAYMRLSKLPEAEHWYmESLRSKTDHIPAHLTYGKLLALTGRKSEAEKFF 700
Cdd:COG4700 159 SSDAhlLY---ARALEALGDLEAAEAEL-EALARRYSGPEARYRYAKFLARQGRTAEAKELL 216
TPR_12 pfam13424
Tetratricopeptide repeat;
526-590 5.15e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 45.07  E-value: 5.15e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 50962841   526 MADMLYNLGLLLQENSRFAEALHYYKLAI--------GSRPTLASAYLNTGIILMNQGKTEEARRTFLKCSEI 590
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALeiarrllgPDHPLTATTLLNLGRLYLELGRYEEALELLERALAL 74
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 749-812 1.79e-05

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 43.09  E-value: 1.79e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 50962841   749 FNAAHMLRQASLNEAAEKYYDLAARLRPNYP---AALMNLGAILHLNGRLQKAEANYLRALQLKPDD 812
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFPESPdaaAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 611-811 2.68e-05

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 46.56  E-value: 2.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   611 NLGKLYHEQGRYEEALSVYREAIQKMPRHFAPqslYNMMGEAYMRLsklpeaehwymeslrsktdhipahltygkllalt 690
Cdd:TIGR02521  36 QLALGYLEQGDLEVAKENLDKALEHDPDDYLA---YLALALYYQQL---------------------------------- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   691 GRKSEAEKFFLKAIELDPTKGNCYMHYGQFLLEESRLteaaemakkaaeldntefdvvfnaahmlrqaslnEAAEKYYDL 770
Cdd:TIGR02521  79 GELEKAEDSFRRALTLNPNNGDVLNNYGTFLCQQGKY----------------------------------EQAMQQFEQ 124

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 50962841   771 AARLrPNYP---AALMNLGAILHLNGRLQKAEANYLRALQLKPD 811
Cdd:TIGR02521 125 AIED-PLYPqpaRSLENAGLCALKAGDFDKAEKYLTRALQIDPQ 167
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 609-638 2.89e-05

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 41.74  E-value: 2.89e-05
                          10        20        30
                  ....*....|....*....|....*....|
gi 50962841   609 LYNLGKLYHEQGRYEEALSVYREAIQKMPR 638
Cdd:pfam07719   4 LYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 608-639 3.14e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 41.66  E-value: 3.14e-05
                           10        20        30
                   ....*....|....*....|....*....|..
gi 50962841    608 CLYNLGKLYHEQGRYEEALSVYREAIQKMPRH 639
Cdd:smart00028   3 ALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_11 pfam13414
TPR repeat;
613-656 3.84e-05

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 41.30  E-value: 3.84e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 50962841   613 GKLYHEQGRYEEALSVYREAIQKMPRhfAPQSLYNmMGEAYMRL 656
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPD--NPEAYYN-LGLAYYKL 41
COG3899 COG3899
Predicted ATPase [General function prediction only];
510-634 4.08e-05

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 47.55  E-value: 4.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841  510 SEAESAYRNALFYRsnMADMLYNLGLLLQENSRFAEALH------YYKLAIGSRPTLASAYLNTGIILMnqGKTEEARRT 583
Cdd:COG3899  737 PDPEEEYRLALLLE--LAEALYLAGRFEEAEALLERALAaralaaLAALRHGNPPASARAYANLGLLLL--GDYEEAYEF 812

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 50962841  584 FLKCSEIPDEnlkdpHAHKSSVTSCLYNLGKLYHEQGRYEEALSVYREAIQ 634
Cdd:COG3899  813 GELALALAER-----LGDRRLEARALFNLGFILHWLGPLREALELLREALE 858
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 536-806 4.17e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.39  E-value: 4.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   536 LLQENsRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGKTEEARRTFLKCSEIpdenlkdphahKSSVTSCLYNLGKL 615
Cdd:TIGR02917  32 YLQKN-KYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSL-----------GYPKNQVLPLLARA 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   616 YHEQGRYEEALSvYREAIQKMPRHFAPQsLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSE 695
Cdd:TIGR02917 100 YLLQGKFQQVLD-ELPGKTLLDDEGAAE-LLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDE 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   696 AEKFFLKAIELDPtkgncymhygqflleesrlteaaemakkaaelDNTEfdvvfnaAHMLRqASL------NEAAEKYYD 769
Cdd:TIGR02917 178 ARALIDEVLTADP--------------------------------GNVD-------ALLLK-GDLllslgnIELALAAYR 217

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 50962841   770 LAARLRPNYPAALMNLGAILHLNGRLQKAE---------------ANYLRAL 806
Cdd:TIGR02917 218 KAIALRPNNIAVLLALATILIEAGEFEEAEkhadallkkapnsplAHYLKAL 269
TPR_1 pfam00515
Tetratricopeptide repeat;
779-812 5.02e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 40.87  E-value: 5.02e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 50962841   779 PAALMNLGAILHLNGRLQKAEANYLRALQLKPDD 812
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
BamD COG4105
Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope ...
 561-661 5.44e-05

Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443281 [Multi-domain]  Cd Length: 254  Bit Score: 45.64  E-value: 5.44e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 561 ASAYLNTGIILMNQGKTEEARRTFlkcseipdENLKD-----PHAHKSsvtscLYNLGKLYHEQGRYEEALSVYREAIQK 635
Cdd:COG4105  32 AEELYEEAKEALEKGDYEKAIKLF--------EELEPrypgsPYAEQA-----QLMLAYAYYKQGDYEEAIAAADRFIKL 98

                        90       100
                ....*....|....*....|....*..
gi 50962841 636 MPRH-FAPQSLYnMMGEAYMRLSKLPE 661
Cdd:COG4105  99 YPNSpNADYAYY-LRGLSYYEQSPDSD 124
TPR_1 pfam00515
Tetratricopeptide repeat;
609-639 8.87e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 40.10  E-value: 8.87e-05
                          10        20        30
                  ....*....|....*....|....*....|.
gi 50962841   609 LYNLGKLYHEQGRYEEALSVYREAIQKMPRH 639
Cdd:pfam00515   4 LYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
Mgr3-like cd24145
Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; ...
 477-635 1.03e-04

Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; Mgr3 (also called mitochondrial genome-required protein 3) is a component of the mitochondrial inner membrane i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins. The supercomplex is composed of Mgr1, Mgr3, and Yme1. Mgr3, together with Mgr1, functions in an adapter complex that targets substrates to the i-AAA protease for degradation.


Pssm-ID: 467945 [Multi-domain]  Cd Length: 307  Bit Score: 45.03  E-value: 1.03e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 477 WQNEEMLYRSGIKVNPaKAWG----NLGNVLKSQSKISEAESAYRNALFYRSNMADMLYNLG-LLLQENSRFAEALHYYK 551
Cdd:cd24145 128 KAVEILLKLGELWMSP-SEVGafleELATAYDLYGRFCLALPLYMQALSLKGQILLSQANCHsLVLMNNEAAELALHALR 206

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 552 LAIGSRPTLASAYLNTGiilmNQGKTEEARRTF---LKCSEIPDENLKDPHAHKSSVTScLYNLGKLYHEQGRYEEALSV 628
Cdd:cd24145 207 KPLSSTLIEASRLPQKS----RDQLLEAALKWAqkaLDVAKSIKPKDRDPECDQACALA-LYNLGVIAEMLGNLDEARKL 281


                ....*..
gi 50962841 629 YREAIQK 635
Cdd:cd24145 282 YKEAISL 288
TPR_7 pfam13176
Tetratricopeptide repeat;
608-634 1.38e-04

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 39.83  E-value: 1.38e-04
                          10        20
                  ....*....|....*....|....*..
gi 50962841   608 CLYNLGKLYHEQGRYEEALSVYREAIQ 634
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALA 27
COG3899 COG3899
Predicted ATPase [General function prediction only];
543-806 1.47e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 45.62  E-value: 1.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841  543 FAEALHYYKLAI------GSRPTLASAYLNTGIILMNQGKTEEARRTFLKC--SEIPDENLKDPHAHKSSVTSCLYNLGK 614
Cdd:COG3899  721 YAEALRYLERALellppdPEEEYRLALLLELAEALYLAGRFEEAEALLERAlaARALAALAALRHGNPPASARAYANLGL 800

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841  615 LYHeqGRYEEALSVYREAIQKMPRHFAPQSL---YNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTG 691
Cdd:COG3899  801 LLL--GDYEEAYEFGELALALAERLGDRRLEaraLFNLGFILHWLGPLREALELLREALEAGLETGDAALALLALAAAAA 878

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841  692 RKSEAEkfflkaieldptkgncymhygqfLLEESRLTEAAEMAKKAAELDNTEFDVVFNAAHMLRQASLNEAAEKYYDLA 771
Cdd:COG3899  879 AAAAAA-----------------------ALAAAAAAAARLLAAAAAALAAAAAAAALAAAELARLAAAAAAAAALALAA 935

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 50962841  772 ARL-----RPNYPAALMNLGAILHLNGRLQKAEANYLRAL 806
Cdd:COG3899  936 AAAaaaaaALAAAAAAAALAAALALAAAAAAAAAAALAAA 975
ycf3 CHL00033
photosystem I assembly protein Ycf3
 505-589 1.80e-04

photosystem I assembly protein Ycf3


Pssm-ID: 176974 [Multi-domain]  Cd Length: 168  Bit Score: 43.07  E-value: 1.80e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841  505 SQSKISEAESAYRNALFYRSNMAD---MLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGII-------LMNQ 574
Cdd:CHL00033  47 SEGEYAEALQNYYEAMRLEIDPYDrsyILYNIGLIHTSNGEHTKALEYYFQALERNPFLPQALNNMAVIchyrgeqAIEQ 126

                         90
                 ....*....|....*
gi 50962841  575 GKTEEARRTFLKCSE 589
Cdd:CHL00033 127 GDSEIAEAWFDQAAE 141
TPR_12 pfam13424
Tetratricopeptide repeat;
750-811 2.29e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 40.45  E-value: 2.29e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   750 NAAHMLRQASLNEAAEKYYDLAARL--------RPNYPAALMNLGAILHLNGRLQKAEANYLRALQLKPD 811
Cdd:pfam13424   8 NLAAVLRRLGRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 469-554 4.01e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 40.75  E-value: 4.01e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 469 KTAIRNGDWQNEEMLYRSGIKVNP-----AKAWGNLGNVLKSQSKISEAESAYRNALFYRSN---MADMLYNLGLLLQEN 540
Cdd:COG1729   1 KALLKAGDYDEAIAAFKAFLKRYPnsplaPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYLEL 80

                        90
                ....*....|....
gi 50962841 541 SRFAEALHYYKLAI 554
Cdd:COG1729  81 GDYDKARATLEELI 94
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 779-812 4.77e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 38.20  E-value: 4.77e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 50962841    779 PAALMNLGAILHLNGRLQKAEANYLRALQLKPDD 812
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_10 pfam13374
Tetratricopeptide repeat;
605-634 4.94e-04

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 38.25  E-value: 4.94e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 50962841   605 VTSCLYNLGKLYHEQGRYEEALSVYREAIQ 634
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALA 30
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 565-634 5.25e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 39.24  E-value: 5.25e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   565 LNTGIILMNQGKTEEARRTFlkcSEIPDENLKDPHAHkssvtSCLYNLGKLYHEQGRYEEALSVYREAIQ 634
Cdd:pfam13432   1 LALARAALRAGDYDDAAAAL---EAALARFPESPDAA-----AALLLLGLAALRQGRLAEAAAAYRAALR 62
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 498-558 5.73e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 38.86  E-value: 5.73e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 50962841   498 NLGNVLKSQSKISEAESAYRNALFYRSN---MADMLYNLGLLLQENSRFAEALHYYKLAIGSRP 558
Cdd:pfam13432   2 ALARAALRAGDYDDAAAALEAALARFPEspdAAAALLLLGLAALRQGRLAEAAAAYRAALRAAP 65
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
611-723 6.63e-04

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 42.18  E-value: 6.63e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 611 NLGKLYHEQGRYEEALSVYREAIQKmprhFAPQSLYNMMG--EAYMRLSKLPEAEHwYMESLRSK---TDHIPAHLTYGK 685
Cdd:COG4700  94 RLADALLELGRYDEAIELYEEALTG----IFADDPHILLGlaQALFELGRYAEALE-TLEKLIAKnpdFKSSDAHLLYAR 168

                        90       100       110
                ....*....|....*....|....*....|....*....
gi 50962841 686 LLALTGRKSEAEKFFLKAIELDPT-KGNCYmhYGQFLLE 723
Cdd:COG4700 169 ALEALGDLEAAEAELEALARRYSGpEARYR--YAKFLAR 205
TPR_12 pfam13424
Tetratricopeptide repeat;
493-554 7.07e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.91  E-value: 7.07e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   493 AKAWGNLGNVLKSQSKISEAESAYRNAL-FYRS-------NMADMLYNLGLLLQENSRFAEALHYYKLAI 554
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALeIARRllgpdhpLTATTLLNLGRLYLELGRYEEALELLERAL 72
TPR_12 pfam13424
Tetratricopeptide repeat;
609-706 1.10e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.52  E-value: 1.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   609 LYNLGKLYHEQGRYEEALSVYREAIQkmprhfapqslynmmgeaymRLSKLPEAEHwymeslrskTDHIPAHLTYGKLLA 688
Cdd:pfam13424   6 LNNLAAVLRRLGRYDEALELLEKALE--------------------IARRLLGPDH---------PLTATTLLNLGRLYL 56

                          90
                  ....*....|....*...
gi 50962841   689 LTGRKSEAEKFFLKAIEL 706
Cdd:pfam13424  57 ELGRYEEALELLERALAL 74
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 610-676 1.19e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 38.09  E-value: 1.19e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 50962841   610 YNLGKLYHEQGRYEEALSVYREAIQKMPRH-FAPQSLYNMmGEAYMRLSKLPEAEHWYMESLRSKTDH 676
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFPESpDAAAALLLL-GLAALRQGRLAEAAAAYRAALRAAPGD 67
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
498-640 1.22e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 41.41  E-value: 1.22e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 498 NLGNVLKSQSKISEAESAYRNAL--FYRSNMaDMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLAS--AYLNTGIILMN 573
Cdd:COG4700  94 RLADALLELGRYDEAIELYEEALtgIFADDP-HILLGLAQALFELGRYAEALETLEKLIAKNPDFKSsdAHLLYARALEA 172

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 574 QGKTEEARRTFlkcsEIPDENLKDPHAhkssvtscLYNLGKLYHEQGRYEEALSVYREAI---QKMPRHF 640
Cdd:COG4700 173 LGDLEAAEAEL----EALARRYSGPEA--------RYRYAKFLARQGRTAEAKELLEEILdeaKHMPKHY 230
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 779-811 1.26e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 37.12  E-value: 1.26e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 50962841   779 PAALMNLGAILHLNGRLQKAEANYLRALQLKPD 811
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 762-812 1.44e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 41.46  E-value: 1.44e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|.
gi 50962841 762 EAAEKYYDLAARLRPNYPAALMNLGAILHLNGRLQKAEANYLRALQLKPDD 812
Cdd:cd24142  17 ELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDG 67
TPR_8 pfam13181
Tetratricopeptide repeat;
609-634 2.01e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 36.22  E-value: 2.01e-03
                          10        20
                  ....*....|....*....|....*.
gi 50962841   609 LYNLGKLYHEQGRYEEALSVYREAIQ 634
Cdd:pfam13181   4 YYNLGLIYLKLGDYEEAKEYYEKALE 29
DUF3856 pfam12968
Domain of Unknown Function (DUF3856); TPR-like protein. The 2hr2 structure belongs to the SCOP ...
 618-706 2.05e-03

Domain of Unknown Function (DUF3856); TPR-like protein. The 2hr2 structure belongs to the SCOP all alpha class, TPR-like superfamily, CT2138-like family. A DALI search gives hits with the putative peptidyl-prolyl isomerase 2fbn (Z=16), the SGTA protein (Z=16), the PLCR protein 2qfc (Z=16), a putative FK506-binding protein (PDB:1qz2-A; DALI Z-score 15.3; RMSD 2.9; 16% sequence identity within 132 superimposed residues), and with the tetratricopeptide repeats of the protein phosphatase 5 (PDB:2bug; DALI Z-score 15.1; RMSD 2.5; 19% sequence identity within 117 superimposed residues).


Pssm-ID: 463761 [Multi-domain]  Cd Length: 142  Bit Score: 39.46  E-value: 2.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   618 EQGRYEEALSVYREAIQkMPRHFAPQSLYNMMG----------EAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKL- 686
Cdd:pfam12968  21 EAAAFEEAAESYRRAME-MSRTIPTEEAFDYDGfdafchaglsEALIGLGRYEEALHSAEKALRYFNRRGELHQDEGKLw 99

                          90       100       110
                  ....*....|....*....|....*....|
gi 50962841   687 --------LAL--TGRKSEAEKFFLKAIEL 706
Cdd:pfam12968 100 iaavfskaRALegLGRKEEAIKYFRMAGEM 129
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 531-586 2.53e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 37.32  E-value: 2.53e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 50962841   531 YNLGLLLQENSRFAEALHYYKLAIGSRPTL---ASAYLNTGIILMNQGKTEEARRTFLK 586
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFPESpdaAAALLLLGLAALRQGRLAEAAAAYRA 59
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 762-830 2.62e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 38.43  E-value: 2.62e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 50962841 762 EAAEKYYDLAARLRPN---YPAALMNLGAILHLNGRLQKAEANYLRALQLKPDDVITQSNLRKLWNIMEKQG 830
Cdd:COG1729  10 DEAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLELG 81
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 609-719 2.72e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 40.69  E-value: 2.72e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 609 LYNLGKLYHEQGRYEEALSVYREAIQKMPrhfapqslynmmgeaymrlsklpeaehwymeslrsktDHIPAHLTYGKLLA 688
Cdd:cd24142   3 LLEKAEELLDQGNFELALKFLQRALELEP-------------------------------------NNVEALELLGEILL 45

                        90       100       110
                ....*....|....*....|....*....|...
gi 50962841 689 LTGRKSEAEKFFLKAIELDPTkGNC--YMHYGQ 719
Cdd:cd24142  46 ELGDVEEAREVLLRAIELDPD-GGYekYLYLGQ 77
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 538-811 3.46e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 40.28  E-value: 3.46e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 538 QENSRFAEALHYYKLAIGSRPTLASAYLNTGI-ILMNQGKTEEARRTFlkcSEIPDENLKDPHAhkssvtscLYNLGKLY 616
Cdd:COG3071  61 QALGDYERRDEYLAQALELAPEAELAVLLTRAeLLLDQGQAEQALATL---EALRAGAPRHPQV--------LRLLLQAY 129

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 617 HEQGRYEEALSVYREAIQKmpRHFAPQSLYNMMGEAYMRL----SKLPEA--EHWymESLRSKTDHIPA-HLTYGKLLAL 689
Cdd:COG3071 130 RQLGDWEELLELLPALRKH--KALSAEEAQALERRAYLGLlrqaARDAEAlkALW--KALPRAERRDPElAAAYARALIA 205

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841 690 TGRKSEAEKFFLKAIELDPTKGNCYmHYGQFLLE---------ESRLTEAAEMAKKAAELdntefdvvfnaAHMLRQASL 760
Cdd:COG3071 206 LGDHDEAERLLREALKRQWDPRLVR-LYGRLQGGdpakqlkraEKWLKKHPNDPDLLLAL-----------GRLCLRNQL 273

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|.
gi 50962841 761 NEAAEKYYDLAARLRPNyPAALMNLGAILHLNGRLQKAEANYLRALQLKPD 811
Cdd:COG3071 274 WGKAREYLEAALALRPS-AEAYAELARLLEQLGDPEEAAEHYRKALALALG 323
TPR_1 pfam00515
Tetratricopeptide repeat;
493-520 4.40e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.47  E-value: 4.40e-03
                          10        20
                  ....*....|....*....|....*...
gi 50962841   493 AKAWGNLGNVLKSQSKISEAESAYRNAL 520
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKAL 28
ArnT COG1807
PMT family glycosyltransferase ArnT/Agl22, involved in glycosylation of proteins and lipid IVA ...
 78-198 5.65e-03

PMT family glycosyltransferase ArnT/Agl22, involved in glycosylation of proteins and lipid IVA [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441412 [Multi-domain]  Cd Length: 309  Bit Score: 39.61  E-value: 5.65e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841  78 AIGGLNPWSYHLVNVLLHAAVTGLFTRFSKALLGDGYWtFMAGLMFASHPIHteAVAGIVGRADVGASLFFLLSLLCYIk 157
Cdd:COG1807  77 KLFGVSEFAARLPSALLGLLTVLLVYLLARRLFGRRAA-LLAALLLLTSPLL--LLFGRLATPDALLLLFWTLALYALL- 152

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 50962841 158 hcstRGYSARTWGWFLGTGLCAGCSMLWKEQGVTVLAVSAV 198
Cdd:COG1807 153 ----RALERRRLRWLLLAGLALGLGFLTKGPVALLLPGLAL 189
TPR_19 pfam14559
Tetratricopeptide repeat;
619-686 7.26e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 35.64  E-value: 7.26e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 50962841   619 QGRYEEALSVYREAIQKMPRHFApqsLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKL 686
Cdd:pfam14559   1 EGDYAEALELLEQALAEDPDNAE---ARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 572-706 7.56e-03

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 39.60  E-value: 7.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   572 MNQGKTEEARR-TFLKCSEIPDENlkdpHAHKSSVTSCLynlGKLYHEQGRYEEALSVYREAIQKMPRHFAP-QSLYNMM 649
Cdd:pfam17874  12 ISKGDAERALElAEQALALLPEDD----LLARGLATFVL---GEAYLCLGDLDAALQAMREAEALARRADSPhVTLWALL 84

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 50962841   650 GEAYMRLSK--LPEAEHWYMESLRSKTD----HIPAHL----TYGKLLALTGRKSEAEKFFLKAIEL 706
Cdd:pfam17874  85 QQGEILRAQgrLHQALETYQQALQLARDhglqHLPLHGfllvGLADLLYEWNDLEEAEQHAQQGIQL 151
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 471-583 7.62e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 7.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50962841   471 AIRNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKsQSKISEAESAYRNALFYRSNMADMLYNLGLLLQENSRFAEALH 548
Cdd:TIGR02917 780 YLAQKDYDKAIKHYQTVVKKAPdnAVVLNNLAWLYL-ELKDPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALP 858

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 50962841   549 YYKLAIGSRPTLASAYLNTGIILMNQGKTEEARRT 583
Cdd:TIGR02917 859 LLRKAVNIAPEAAAIRYHLALALLATGRKAEARKE 893
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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