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Conserved domains on  [gi|28573055|ref|NP_788654|]
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midline fasciclin, isoform M [Drosophila melanogaster]

Protein Classification

fasciclin domain-containing protein( domain architecture ID 10651152)

fasciclin domain-containing protein may be involved in cell adhesion; similar to Drosophila melanogaster midline Fasciclin, a Drosophila fasciclin-I-related membrane protein localized to the CNS midline cells and trachea

CATH:  2.30.180.10
Gene Ontology:  GO:0007155
SCOP:  4002728

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Fasciclin pfam02469
Fasciclin domain; This extracellular domain is found repeated four times in grasshopper ...
397-527 3.14e-27

Fasciclin domain; This extracellular domain is found repeated four times in grasshopper fasciclin I as well as in proteins from mammals, sea urchins, plants, yeast and bacteria.


:

Pssm-ID: 396845  Cd Length: 123  Bit Score: 106.95  E-value: 3.14e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055   397 ADMSIMRTVLEKTNLSAMLED-DKPVTIFVPTDAAFDKLEPHLRRALKEGRGCASNILKNHLLDLTFCSLATVPGakTTA 475
Cdd:pfam02469   1 PGFSTFVALLKAAGLVDTLNGsQGPFTVFAPTNEAFAKLPAGTLNFLLKDKEQLKNLLKYHVVPGRLTSSDLKNG--GTL 78
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 28573055   476 YNLLGEPLLLNRTHraanqtgpTPIYINNlAKIIDADIMGTNGVLHVIDTIL 527
Cdd:pfam02469  79 ATLQGSKLRVNVTG--------GSVTVNG-ARVVQADIEATNGVIHVIDKVL 121
Fasciclin pfam02469
Fasciclin domain; This extracellular domain is found repeated four times in grasshopper ...
542-675 1.55e-25

Fasciclin domain; This extracellular domain is found repeated four times in grasshopper fasciclin I as well as in proteins from mammals, sea urchins, plants, yeast and bacteria.


:

Pssm-ID: 396845  Cd Length: 123  Bit Score: 102.33  E-value: 1.55e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055   542 KNLTIFQRLLEASGYDDQF-DDLDNVTIFAPTDKAlqnteWARMLKEQPE-LLNHNLDLLEFLNYHVVKPMIKTCDL-SE 618
Cdd:pfam02469   1 PGFSTFVALLKAAGLVDTLnGSQGPFTVFAPTNEA-----FAKLPAGTLNfLLKDKEQLKNLLKYHVVPGRLTSSDLkNG 75
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 28573055   619 KSLPTVAGSSVRLNLYSthalfsdvmNRATVNCARLVHFDDESCGSVLHQVDRALAP 675
Cdd:pfam02469  76 GTLATLQGSKLRVNVTG---------GSVTVNGARVVQADIEATNGVIHVIDKVLLP 123
Fasciclin pfam02469
Fasciclin domain; This extracellular domain is found repeated four times in grasshopper ...
688-810 8.19e-23

Fasciclin domain; This extracellular domain is found repeated four times in grasshopper fasciclin I as well as in proteins from mammals, sea urchins, plants, yeast and bacteria.


:

Pssm-ID: 396845  Cd Length: 123  Bit Score: 94.24  E-value: 8.19e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055   688 PNYSKFLELVRKANLTQLLSNDSRSLTLLVPKNDIFEELNESGEGSKPADP---MALVKTHIVEDVVCCAGIIPTnwpfv 764
Cdd:pfam02469   1 PGFSTFVALLKAAGLVDTLNGSQGPFTVFAPTNEAFAKLPAGTLNFLLKDKeqlKNLLKYHVVPGRLTSSDLKNG----- 75
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 28573055   765 RSIESISGQHLRITRDR-RPKIENAGVTKCDVVATNGILHEINDIIV 810
Cdd:pfam02469  76 GTLATLQGSKLRVNVTGgSVTVNGARVVQADIEATNGVIHVIDKVLL 122
FAS1 smart00554
Four repeated domains in the Fasciclin I family of proteins, present in many other contexts;
274-385 1.46e-10

Four repeated domains in the Fasciclin I family of proteins, present in many other contexts;


:

Pssm-ID: 214719  Cd Length: 97  Bit Score: 58.53  E-value: 1.46e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055    274 TLFVPNDAAFMEYRghhQQENNVEDAKaeasKPSIYKLHAVLGEVQLEDVPNEKLLQTeLPDQKIRINSYQlpaalglEP 353
Cdd:smart00554   1 TVFAPTDEAFQKLP---PDLNSLLADK----LKNLLLYHVVPGRLSSADLLNGGTLPT-LAGSKLRITRSG-------GS 65
                           90       100       110
                   ....*....|....*....|....*....|..
gi 28573055    354 YRFAANCVPIEKHDKLSEQALVHTLGGVLKPL 385
Cdd:smart00554  66 GTVTVNGARIVEADIAATNGVVHVIDRVLLPP 97
 
Name Accession Description Interval E-value
Fasciclin pfam02469
Fasciclin domain; This extracellular domain is found repeated four times in grasshopper ...
397-527 3.14e-27

Fasciclin domain; This extracellular domain is found repeated four times in grasshopper fasciclin I as well as in proteins from mammals, sea urchins, plants, yeast and bacteria.


Pssm-ID: 396845  Cd Length: 123  Bit Score: 106.95  E-value: 3.14e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055   397 ADMSIMRTVLEKTNLSAMLED-DKPVTIFVPTDAAFDKLEPHLRRALKEGRGCASNILKNHLLDLTFCSLATVPGakTTA 475
Cdd:pfam02469   1 PGFSTFVALLKAAGLVDTLNGsQGPFTVFAPTNEAFAKLPAGTLNFLLKDKEQLKNLLKYHVVPGRLTSSDLKNG--GTL 78
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 28573055   476 YNLLGEPLLLNRTHraanqtgpTPIYINNlAKIIDADIMGTNGVLHVIDTIL 527
Cdd:pfam02469  79 ATLQGSKLRVNVTG--------GSVTVNG-ARVVQADIEATNGVIHVIDKVL 121
Fasciclin pfam02469
Fasciclin domain; This extracellular domain is found repeated four times in grasshopper ...
542-675 1.55e-25

Fasciclin domain; This extracellular domain is found repeated four times in grasshopper fasciclin I as well as in proteins from mammals, sea urchins, plants, yeast and bacteria.


Pssm-ID: 396845  Cd Length: 123  Bit Score: 102.33  E-value: 1.55e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055   542 KNLTIFQRLLEASGYDDQF-DDLDNVTIFAPTDKAlqnteWARMLKEQPE-LLNHNLDLLEFLNYHVVKPMIKTCDL-SE 618
Cdd:pfam02469   1 PGFSTFVALLKAAGLVDTLnGSQGPFTVFAPTNEA-----FAKLPAGTLNfLLKDKEQLKNLLKYHVVPGRLTSSDLkNG 75
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 28573055   619 KSLPTVAGSSVRLNLYSthalfsdvmNRATVNCARLVHFDDESCGSVLHQVDRALAP 675
Cdd:pfam02469  76 GTLATLQGSKLRVNVTG---------GSVTVNGARVVQADIEATNGVIHVIDKVLLP 123
Fasciclin pfam02469
Fasciclin domain; This extracellular domain is found repeated four times in grasshopper ...
688-810 8.19e-23

Fasciclin domain; This extracellular domain is found repeated four times in grasshopper fasciclin I as well as in proteins from mammals, sea urchins, plants, yeast and bacteria.


Pssm-ID: 396845  Cd Length: 123  Bit Score: 94.24  E-value: 8.19e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055   688 PNYSKFLELVRKANLTQLLSNDSRSLTLLVPKNDIFEELNESGEGSKPADP---MALVKTHIVEDVVCCAGIIPTnwpfv 764
Cdd:pfam02469   1 PGFSTFVALLKAAGLVDTLNGSQGPFTVFAPTNEAFAKLPAGTLNFLLKDKeqlKNLLKYHVVPGRLTSSDLKNG----- 75
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 28573055   765 RSIESISGQHLRITRDR-RPKIENAGVTKCDVVATNGILHEINDIIV 810
Cdd:pfam02469  76 GTLATLQGSKLRVNVTGgSVTVNGARVVQADIEATNGVIHVIDKVLL 122
FAS1 COG2335
Uncaracterized surface protein containing fasciclin (FAS1) repeats [General function ...
386-527 3.13e-21

Uncaracterized surface protein containing fasciclin (FAS1) repeats [General function prediction only];


Pssm-ID: 441906 [Multi-domain]  Cd Length: 164  Bit Score: 91.12  E-value: 3.13e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055 386 TKNLMDIIRERADMSIMRTVLEKTNLSAMLEDDKPVTIFVPTDAAFDKLEPHLRRALK--EGRGCASNILKNHLldltfc 463
Cdd:COG2335  30 TKNIVETAANNPDFSTLVAALKAAGLVDTLSGEGPFTVFAPTDAAFAALPAGTLDALLkpENKATLTKILTYHV------ 103
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28573055 464 slatVPGAKTTAY--------NLLGEPLLLNRTHRAanqtgptpIYINNlAKIIDADIMGTNGVLHVIDTIL 527
Cdd:COG2335 104 ----VPGKVTAADlkdgktltTLQGQTLTVTVSGGG--------VTVNG-ANVITADIEASNGVIHVIDKVL 162
FAS1 smart00554
Four repeated domains in the Fasciclin I family of proteins, present in many other contexts;
422-527 1.62e-19

Four repeated domains in the Fasciclin I family of proteins, present in many other contexts;


Pssm-ID: 214719  Cd Length: 97  Bit Score: 83.95  E-value: 1.62e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055    422 TIFVPTDAAFDKLEPHLRRALKEgrgCASNILKNHLLDLTFCSLATVPGAKTTAynLLGEPLLLNRTHraanqtGPTPIY 501
Cdd:smart00554   1 TVFAPTDEAFQKLPPDLNSLLAD---KLKNLLLYHVVPGRLSSADLLNGGTLPT--LAGSKLRITRSG------GSGTVT 69
                           90       100
                   ....*....|....*....|....*.
gi 28573055    502 INNlAKIIDADIMGTNGVLHVIDTIL 527
Cdd:smart00554  70 VNG-ARIVEADIAATNGVVHVIDRVL 94
FAS1 smart00554
Four repeated domains in the Fasciclin I family of proteins, present in many other contexts;
567-676 5.09e-17

Four repeated domains in the Fasciclin I family of proteins, present in many other contexts;


Pssm-ID: 214719  Cd Length: 97  Bit Score: 77.02  E-value: 5.09e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055    567 TIFAPTDKALQNTEWARmlkeqPELLNHnlDLLEFLNYHVVKPMIKTCDL-SEKSLPTVAGSSVRLNLYSThalfsdvMN 645
Cdd:smart00554   1 TVFAPTDEAFQKLPPDL-----NSLLAD--KLKNLLLYHVVPGRLSSADLlNGGTLPTLAGSKLRITRSGG-------SG 66
                           90       100       110
                   ....*....|....*....|....*....|.
gi 28573055    646 RATVNCARLVHFDDESCGSVLHQVDRALAPP 676
Cdd:smart00554  67 TVTVNGARIVEADIAATNGVVHVIDRVLLPP 97
FAS1 COG2335
Uncaracterized surface protein containing fasciclin (FAS1) repeats [General function ...
661-810 9.40e-15

Uncaracterized surface protein containing fasciclin (FAS1) repeats [General function prediction only];


Pssm-ID: 441906 [Multi-domain]  Cd Length: 164  Bit Score: 72.63  E-value: 9.40e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055 661 SCGSVLHQVDRALAPPKNnMLKLLEANPNYSKFLELVRKANLTQLLSNDsRSLTLLVPKNDIFEELNES--GEGSKPADP 738
Cdd:COG2335  15 ACASSAAAEGAAMAPTKN-IVETAANNPDFSTLVAALKAAGLVDTLSGE-GPFTVFAPTDAAFAALPAGtlDALLKPENK 92
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 28573055 739 ---MALVKTHIVEDVVCCAGIIPTnwpfvRSIESISGQHLRITR-DRRPKIENAGVTKCDVVATNGILHEINDIIV 810
Cdd:COG2335  93 atlTKILTYHVVPGKVTAADLKDG-----KTLTTLQGQTLTVTVsGGGVTVNGANVITADIEASNGVIHVIDKVLL 163
FAS1 smart00554
Four repeated domains in the Fasciclin I family of proteins, present in many other contexts;
714-809 1.16e-14

Four repeated domains in the Fasciclin I family of proteins, present in many other contexts;


Pssm-ID: 214719  Cd Length: 97  Bit Score: 70.08  E-value: 1.16e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055    714 TLLVPKNDIFEELNESGEGSKPADPMALVKTHIVEDVVCCAGIIPTNwpfvrSIESISGQHLRITRDRRP---KIENAGV 790
Cdd:smart00554   1 TVFAPTDEAFQKLPPDLNSLLADKLKNLLLYHVVPGRLSSADLLNGG-----TLPTLAGSKLRITRSGGSgtvTVNGARI 75
                           90
                   ....*....|....*....
gi 28573055    791 TKCDVVATNGILHEINDII 809
Cdd:smart00554  76 VEADIAATNGVVHVIDRVL 94
FAS1 COG2335
Uncaracterized surface protein containing fasciclin (FAS1) repeats [General function ...
538-675 8.50e-11

Uncaracterized surface protein containing fasciclin (FAS1) repeats [General function prediction only];


Pssm-ID: 441906 [Multi-domain]  Cd Length: 164  Bit Score: 61.08  E-value: 8.50e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055 538 LMSQKNLTIFQRLLEASGYDDQFDDLDNVTIFAPTDKALqntewARMLKEQPE-LLNH-NLDLL-EFLNYHVVKPMIKTC 614
Cdd:COG2335  37 AANNPDFSTLVAALKAAGLVDTLSGEGPFTVFAPTDAAF-----AALPAGTLDaLLKPeNKATLtKILTYHVVPGKVTAA 111
                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28573055 615 DLSE-KSLPTVAGSSVRLNLysthalfSDvmNRATVNCARLVHFDDESCGSVLHQVDRALAP 675
Cdd:COG2335 112 DLKDgKTLTTLQGQTLTVTV-------SG--GGVTVNGANVITADIEASNGVIHVIDKVLLP 164
FAS1 smart00554
Four repeated domains in the Fasciclin I family of proteins, present in many other contexts;
274-385 1.46e-10

Four repeated domains in the Fasciclin I family of proteins, present in many other contexts;


Pssm-ID: 214719  Cd Length: 97  Bit Score: 58.53  E-value: 1.46e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055    274 TLFVPNDAAFMEYRghhQQENNVEDAKaeasKPSIYKLHAVLGEVQLEDVPNEKLLQTeLPDQKIRINSYQlpaalglEP 353
Cdd:smart00554   1 TVFAPTDEAFQKLP---PDLNSLLADK----LKNLLLYHVVPGRLSSADLLNGGTLPT-LAGSKLRITRSG-------GS 65
                           90       100       110
                   ....*....|....*....|....*....|..
gi 28573055    354 YRFAANCVPIEKHDKLSEQALVHTLGGVLKPL 385
Cdd:smart00554  66 GTVTVNGARIVEADIAATNGVVHVIDRVLLPP 97
Fasciclin pfam02469
Fasciclin domain; This extracellular domain is found repeated four times in grasshopper ...
247-384 9.74e-08

Fasciclin domain; This extracellular domain is found repeated four times in grasshopper fasciclin I as well as in proteins from mammals, sea urchins, plants, yeast and bacteria.


Pssm-ID: 396845  Cd Length: 123  Bit Score: 51.49  E-value: 9.74e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055   247 GAKQFLESARTAGeLADMLgAGSGKKVTLFVPNDAAFMEYRGhHQQENNVEDAKAeasKPSIYKLHAVLGEVQLEDVPNE 326
Cdd:pfam02469   2 GFSTFVALLKAAG-LVDTL-NGSQGPFTVFAPTNEAFAKLPA-GTLNFLLKDKEQ---LKNLLKYHVVPGRLTSSDLKNG 75
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 28573055   327 KLLQTeLPDQKIRINSYQLpaalglepyRFAANCVPIEKHDKLSEQALVHTLGGVLKP 384
Cdd:pfam02469  76 GTLAT-LQGSKLRVNVTGG---------SVTVNGARVVQADIEATNGVIHVIDKVLLP 123
FAS1 COG2335
Uncaracterized surface protein containing fasciclin (FAS1) repeats [General function ...
237-341 6.61e-03

Uncaracterized surface protein containing fasciclin (FAS1) repeats [General function prediction only];


Pssm-ID: 441906 [Multi-domain]  Cd Length: 164  Bit Score: 38.35  E-value: 6.61e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055 237 KDVEATASdmGAKQF--LESARTAGELADML-GAGSgkkVTLFVPNDAAFMEYrghhqQENNVEDAKAEASKP---SIYK 310
Cdd:COG2335  31 KNIVETAA--NNPDFstLVAALKAAGLVDTLsGEGP---FTVFAPTDAAFAAL-----PAGTLDALLKPENKAtltKILT 100
                        90       100       110
                ....*....|....*....|....*....|.
gi 28573055 311 LHAVLGEVQLEDVPNEKLLQTeLPDQKIRIN 341
Cdd:COG2335 101 YHVVPGKVTAADLKDGKTLTT-LQGQTLTVT 130
 
Name Accession Description Interval E-value
Fasciclin pfam02469
Fasciclin domain; This extracellular domain is found repeated four times in grasshopper ...
397-527 3.14e-27

Fasciclin domain; This extracellular domain is found repeated four times in grasshopper fasciclin I as well as in proteins from mammals, sea urchins, plants, yeast and bacteria.


Pssm-ID: 396845  Cd Length: 123  Bit Score: 106.95  E-value: 3.14e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055   397 ADMSIMRTVLEKTNLSAMLED-DKPVTIFVPTDAAFDKLEPHLRRALKEGRGCASNILKNHLLDLTFCSLATVPGakTTA 475
Cdd:pfam02469   1 PGFSTFVALLKAAGLVDTLNGsQGPFTVFAPTNEAFAKLPAGTLNFLLKDKEQLKNLLKYHVVPGRLTSSDLKNG--GTL 78
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 28573055   476 YNLLGEPLLLNRTHraanqtgpTPIYINNlAKIIDADIMGTNGVLHVIDTIL 527
Cdd:pfam02469  79 ATLQGSKLRVNVTG--------GSVTVNG-ARVVQADIEATNGVIHVIDKVL 121
Fasciclin pfam02469
Fasciclin domain; This extracellular domain is found repeated four times in grasshopper ...
542-675 1.55e-25

Fasciclin domain; This extracellular domain is found repeated four times in grasshopper fasciclin I as well as in proteins from mammals, sea urchins, plants, yeast and bacteria.


Pssm-ID: 396845  Cd Length: 123  Bit Score: 102.33  E-value: 1.55e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055   542 KNLTIFQRLLEASGYDDQF-DDLDNVTIFAPTDKAlqnteWARMLKEQPE-LLNHNLDLLEFLNYHVVKPMIKTCDL-SE 618
Cdd:pfam02469   1 PGFSTFVALLKAAGLVDTLnGSQGPFTVFAPTNEA-----FAKLPAGTLNfLLKDKEQLKNLLKYHVVPGRLTSSDLkNG 75
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 28573055   619 KSLPTVAGSSVRLNLYSthalfsdvmNRATVNCARLVHFDDESCGSVLHQVDRALAP 675
Cdd:pfam02469  76 GTLATLQGSKLRVNVTG---------GSVTVNGARVVQADIEATNGVIHVIDKVLLP 123
Fasciclin pfam02469
Fasciclin domain; This extracellular domain is found repeated four times in grasshopper ...
688-810 8.19e-23

Fasciclin domain; This extracellular domain is found repeated four times in grasshopper fasciclin I as well as in proteins from mammals, sea urchins, plants, yeast and bacteria.


Pssm-ID: 396845  Cd Length: 123  Bit Score: 94.24  E-value: 8.19e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055   688 PNYSKFLELVRKANLTQLLSNDSRSLTLLVPKNDIFEELNESGEGSKPADP---MALVKTHIVEDVVCCAGIIPTnwpfv 764
Cdd:pfam02469   1 PGFSTFVALLKAAGLVDTLNGSQGPFTVFAPTNEAFAKLPAGTLNFLLKDKeqlKNLLKYHVVPGRLTSSDLKNG----- 75
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 28573055   765 RSIESISGQHLRITRDR-RPKIENAGVTKCDVVATNGILHEINDIIV 810
Cdd:pfam02469  76 GTLATLQGSKLRVNVTGgSVTVNGARVVQADIEATNGVIHVIDKVLL 122
FAS1 COG2335
Uncaracterized surface protein containing fasciclin (FAS1) repeats [General function ...
386-527 3.13e-21

Uncaracterized surface protein containing fasciclin (FAS1) repeats [General function prediction only];


Pssm-ID: 441906 [Multi-domain]  Cd Length: 164  Bit Score: 91.12  E-value: 3.13e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055 386 TKNLMDIIRERADMSIMRTVLEKTNLSAMLEDDKPVTIFVPTDAAFDKLEPHLRRALK--EGRGCASNILKNHLldltfc 463
Cdd:COG2335  30 TKNIVETAANNPDFSTLVAALKAAGLVDTLSGEGPFTVFAPTDAAFAALPAGTLDALLkpENKATLTKILTYHV------ 103
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28573055 464 slatVPGAKTTAY--------NLLGEPLLLNRTHRAanqtgptpIYINNlAKIIDADIMGTNGVLHVIDTIL 527
Cdd:COG2335 104 ----VPGKVTAADlkdgktltTLQGQTLTVTVSGGG--------VTVNG-ANVITADIEASNGVIHVIDKVL 162
FAS1 smart00554
Four repeated domains in the Fasciclin I family of proteins, present in many other contexts;
422-527 1.62e-19

Four repeated domains in the Fasciclin I family of proteins, present in many other contexts;


Pssm-ID: 214719  Cd Length: 97  Bit Score: 83.95  E-value: 1.62e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055    422 TIFVPTDAAFDKLEPHLRRALKEgrgCASNILKNHLLDLTFCSLATVPGAKTTAynLLGEPLLLNRTHraanqtGPTPIY 501
Cdd:smart00554   1 TVFAPTDEAFQKLPPDLNSLLAD---KLKNLLLYHVVPGRLSSADLLNGGTLPT--LAGSKLRITRSG------GSGTVT 69
                           90       100
                   ....*....|....*....|....*.
gi 28573055    502 INNlAKIIDADIMGTNGVLHVIDTIL 527
Cdd:smart00554  70 VNG-ARIVEADIAATNGVVHVIDRVL 94
FAS1 smart00554
Four repeated domains in the Fasciclin I family of proteins, present in many other contexts;
567-676 5.09e-17

Four repeated domains in the Fasciclin I family of proteins, present in many other contexts;


Pssm-ID: 214719  Cd Length: 97  Bit Score: 77.02  E-value: 5.09e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055    567 TIFAPTDKALQNTEWARmlkeqPELLNHnlDLLEFLNYHVVKPMIKTCDL-SEKSLPTVAGSSVRLNLYSThalfsdvMN 645
Cdd:smart00554   1 TVFAPTDEAFQKLPPDL-----NSLLAD--KLKNLLLYHVVPGRLSSADLlNGGTLPTLAGSKLRITRSGG-------SG 66
                           90       100       110
                   ....*....|....*....|....*....|.
gi 28573055    646 RATVNCARLVHFDDESCGSVLHQVDRALAPP 676
Cdd:smart00554  67 TVTVNGARIVEADIAATNGVVHVIDRVLLPP 97
FAS1 COG2335
Uncaracterized surface protein containing fasciclin (FAS1) repeats [General function ...
661-810 9.40e-15

Uncaracterized surface protein containing fasciclin (FAS1) repeats [General function prediction only];


Pssm-ID: 441906 [Multi-domain]  Cd Length: 164  Bit Score: 72.63  E-value: 9.40e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055 661 SCGSVLHQVDRALAPPKNnMLKLLEANPNYSKFLELVRKANLTQLLSNDsRSLTLLVPKNDIFEELNES--GEGSKPADP 738
Cdd:COG2335  15 ACASSAAAEGAAMAPTKN-IVETAANNPDFSTLVAALKAAGLVDTLSGE-GPFTVFAPTDAAFAALPAGtlDALLKPENK 92
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 28573055 739 ---MALVKTHIVEDVVCCAGIIPTnwpfvRSIESISGQHLRITR-DRRPKIENAGVTKCDVVATNGILHEINDIIV 810
Cdd:COG2335  93 atlTKILTYHVVPGKVTAADLKDG-----KTLTTLQGQTLTVTVsGGGVTVNGANVITADIEASNGVIHVIDKVLL 163
FAS1 smart00554
Four repeated domains in the Fasciclin I family of proteins, present in many other contexts;
714-809 1.16e-14

Four repeated domains in the Fasciclin I family of proteins, present in many other contexts;


Pssm-ID: 214719  Cd Length: 97  Bit Score: 70.08  E-value: 1.16e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055    714 TLLVPKNDIFEELNESGEGSKPADPMALVKTHIVEDVVCCAGIIPTNwpfvrSIESISGQHLRITRDRRP---KIENAGV 790
Cdd:smart00554   1 TVFAPTDEAFQKLPPDLNSLLADKLKNLLLYHVVPGRLSSADLLNGG-----TLPTLAGSKLRITRSGGSgtvTVNGARI 75
                           90
                   ....*....|....*....
gi 28573055    791 TKCDVVATNGILHEINDII 809
Cdd:smart00554  76 VEADIAATNGVVHVIDRVL 94
FAS1 COG2335
Uncaracterized surface protein containing fasciclin (FAS1) repeats [General function ...
538-675 8.50e-11

Uncaracterized surface protein containing fasciclin (FAS1) repeats [General function prediction only];


Pssm-ID: 441906 [Multi-domain]  Cd Length: 164  Bit Score: 61.08  E-value: 8.50e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055 538 LMSQKNLTIFQRLLEASGYDDQFDDLDNVTIFAPTDKALqntewARMLKEQPE-LLNH-NLDLL-EFLNYHVVKPMIKTC 614
Cdd:COG2335  37 AANNPDFSTLVAALKAAGLVDTLSGEGPFTVFAPTDAAF-----AALPAGTLDaLLKPeNKATLtKILTYHVVPGKVTAA 111
                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28573055 615 DLSE-KSLPTVAGSSVRLNLysthalfSDvmNRATVNCARLVHFDDESCGSVLHQVDRALAP 675
Cdd:COG2335 112 DLKDgKTLTTLQGQTLTVTV-------SG--GGVTVNGANVITADIEASNGVIHVIDKVLLP 164
FAS1 smart00554
Four repeated domains in the Fasciclin I family of proteins, present in many other contexts;
274-385 1.46e-10

Four repeated domains in the Fasciclin I family of proteins, present in many other contexts;


Pssm-ID: 214719  Cd Length: 97  Bit Score: 58.53  E-value: 1.46e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055    274 TLFVPNDAAFMEYRghhQQENNVEDAKaeasKPSIYKLHAVLGEVQLEDVPNEKLLQTeLPDQKIRINSYQlpaalglEP 353
Cdd:smart00554   1 TVFAPTDEAFQKLP---PDLNSLLADK----LKNLLLYHVVPGRLSSADLLNGGTLPT-LAGSKLRITRSG-------GS 65
                           90       100       110
                   ....*....|....*....|....*....|..
gi 28573055    354 YRFAANCVPIEKHDKLSEQALVHTLGGVLKPL 385
Cdd:smart00554  66 GTVTVNGARIVEADIAATNGVVHVIDRVLLPP 97
Fasciclin pfam02469
Fasciclin domain; This extracellular domain is found repeated four times in grasshopper ...
247-384 9.74e-08

Fasciclin domain; This extracellular domain is found repeated four times in grasshopper fasciclin I as well as in proteins from mammals, sea urchins, plants, yeast and bacteria.


Pssm-ID: 396845  Cd Length: 123  Bit Score: 51.49  E-value: 9.74e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055   247 GAKQFLESARTAGeLADMLgAGSGKKVTLFVPNDAAFMEYRGhHQQENNVEDAKAeasKPSIYKLHAVLGEVQLEDVPNE 326
Cdd:pfam02469   2 GFSTFVALLKAAG-LVDTL-NGSQGPFTVFAPTNEAFAKLPA-GTLNFLLKDKEQ---LKNLLKYHVVPGRLTSSDLKNG 75
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 28573055   327 KLLQTeLPDQKIRINSYQLpaalglepyRFAANCVPIEKHDKLSEQALVHTLGGVLKP 384
Cdd:pfam02469  76 GTLAT-LQGSKLRVNVTGG---------SVTVNGARVVQADIEATNGVIHVIDKVLLP 123
FAS1 COG2335
Uncaracterized surface protein containing fasciclin (FAS1) repeats [General function ...
237-341 6.61e-03

Uncaracterized surface protein containing fasciclin (FAS1) repeats [General function prediction only];


Pssm-ID: 441906 [Multi-domain]  Cd Length: 164  Bit Score: 38.35  E-value: 6.61e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573055 237 KDVEATASdmGAKQF--LESARTAGELADML-GAGSgkkVTLFVPNDAAFMEYrghhqQENNVEDAKAEASKP---SIYK 310
Cdd:COG2335  31 KNIVETAA--NNPDFstLVAALKAAGLVDTLsGEGP---FTVFAPTDAAFAAL-----PAGTLDALLKPENKAtltKILT 100
                        90       100       110
                ....*....|....*....|....*....|.
gi 28573055 311 LHAVLGEVQLEDVPNEKLLQTeLPDQKIRIN 341
Cdd:COG2335 101 YHVVPGKVTAADLKDGKTLTT-LQGQTLTVT 130
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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