|
Name |
Accession |
Description |
Interval |
E-value |
| PRK06129 |
PRK06129 |
3-hydroxyacyl-CoA dehydrogenase; Validated |
8-317 |
2.27e-105 |
|
3-hydroxyacyl-CoA dehydrogenase; Validated
Pssm-ID: 235706 [Multi-domain] Cd Length: 308 Bit Score: 310.05 E-value: 2.27e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 8 APGGVAVVGSGLIGRSWAMLFASAGFRVKLFDIEPRQVTDALVSLRKEMKMLELSGYLKGElGAEEQLSLISGCSDLREA 87
Cdd:PRK06129 1 PMGSVAIIGAGLIGRAWAIVFARAGHEVRLWDADPAAAAAAPAYIAGRLEDLAAFDLLDGE-APDAVLARIRVTDSLADA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 88 VEGALHVQECVPENLELKRKLFAQLDKIADDHVILSSSSSCLLPSKLFAGLAHVKQCLVAHPVNPPYYVPLVELVPHPET 167
Cdd:PRK06129 80 VADADYVQESAPENLELKRALFAELDALAPPHAILASSTSALLASAFTEHLAGRERCLVAHPINPPYLIPVVEVVPAPWT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 168 APATVDRTYALMRRVGQSPVRLLREIDGFALNRLQYAVIAEAWRLVEEGVVSPGDLDLVMSDGLGLRYAFIGPLETMHLN 247
Cdd:PRK06129 160 APATLARAEALYRAAGQSPVRLRREIDGFVLNRLQGALLREAFRLVADGVASVDDIDAVIRDGLGLRWSFMGPFETIDLN 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 27805847 248 A-EGMLSYCDRYGEGMKRVLKTFG-PVPeFSGATAEKVHQAMCVKVPddAEHLAARRAWRDGCLMRLAQLKH 317
Cdd:PRK06129 240 ApGGVADYAQRYGPMYRRMAAERGqPVP-WDGELVARVEAERRAALP--LDQLAARQAWRDRRLMALAAHRR 308
|
|
| FadB |
COG1250 |
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA ... |
12-246 |
2.39e-68 |
|
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA dehydrogenase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440862 [Multi-domain] Cd Length: 281 Bit Score: 214.59 E-value: 2.39e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 12 VAVVGSGLIGRSWAMLFASAGFRVKLFDIEPRQVTDALVSLRKEMKMLELSGYLKGElGAEEQLSLISGCSDLrEAVEGA 91
Cdd:COG1250 5 VAVIGAGTMGAGIAAVFANAGYEVVLLDISPEALERARARIAKLLDKLVKKGKLTEE-EADAALARITPTTDL-AALADA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 92 LHVQECVPENLELKRKLFAQLDKIADDHVIlssssscllpsklFA-------------GLAHVKQCLVAHPVNPPYYVPL 158
Cdd:COG1250 83 DLVIEAVPEDLDLKQEVFAELDAVAPPDAI-------------LAsntsslsitelaaATKRPERFIGLHFFNPVPLMPL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 159 VELVPHPETAPATVDRTYALMRRVGQSPVRlLREIDGFALNRLQYAVIAEAWRLVEEGVVSPGDLDLVMSDGLGLRyafI 238
Cdd:COG1250 150 VEVIRGPATSDETVATAVAFARRLGKTPVV-VKDTPGFIVNRILVPYLNEAIRLLEEGVASPEDIDAAMRLGFGFP---M 225
|
....*...
gi 27805847 239 GPLETMHL 246
Cdd:COG1250 226 GPFELADL 233
|
|
| 3HCDH_N |
pfam02737 |
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda ... |
12-189 |
2.67e-57 |
|
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda crystallin.
Pssm-ID: 397037 [Multi-domain] Cd Length: 180 Bit Score: 183.12 E-value: 2.67e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 12 VAVVGSGLIGRSWAMLFASAGFRVKLFDIEPRQVTDALVSLRKEMKMLELSGYLKgELGAEEQLSLISGCSDLREAVeGA 91
Cdd:pfam02737 2 VAVIGAGTMGAGIAQVFALAGLEVVLVDISEEALEKALERIESSLERLVEKGRIT-EEEVDAALARISFTTDLAAAV-DA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 92 LHVQECVPENLELKRKLFAQLDKIADDHVILSSSSSCLLPSKLFAGLAHVKQCLVAHPVNPPYYVPLVELVPHPETAPAT 171
Cdd:pfam02737 80 DLVIEAVPENLELKRKLFAELDAIAPPDAILATNTSSLSITELAAATKRPERFIGLHFFNPPPLMPLVEVVRGEKTSPET 159
|
170
....*....|....*...
gi 27805847 172 VDRTYALMRRVGQSPVRL 189
Cdd:pfam02737 160 VATTVELAKKIGKTPVVV 177
|
|
| fa_ox_alpha_mit |
TIGR02441 |
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ... |
12-224 |
2.44e-08 |
|
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).
Pssm-ID: 131494 [Multi-domain] Cd Length: 737 Bit Score: 55.23 E-value: 2.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 12 VAVVGSGLIGRSWAMLFASAGFRVKLFDIEP----RQVTDALVSLRKEMKMLELSGYLKgelgaEEQLSLISGCSDLrEA 87
Cdd:TIGR02441 338 LAVLGAGLMGAGIAQVSVDKGLKTVLKDATPagldRGQQQVFKGLNKKVKRKKITSLER-----DSILSNLTPTLDY-SG 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 88 VEGALHVQECVPENLELKRKLFAQLDKIADDHVILSSSSSCLLPSKLFAGLAHVKQCLVAHPVNPPYYVPLVELVPHPET 167
Cdd:TIGR02441 412 FKNADMVIEAVFEDLSLKHKVIKEVEAVVPPHCIIASNTSALPIKDIAAVSSRPEKVIGMHYFSPVDKMQLLEIITHDGT 491
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 27805847 168 APATVDRTYALMRRVGQSpVRLLREIDGFALNRLQYAVIAEAWRLVEEGvVSPGDLD 224
Cdd:TIGR02441 492 SKDTLASAVAVGLKQGKV-VIVVKDGPGFYTTRCLGPMLAEVIRLLQEG-VDPKKLD 546
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK06129 |
PRK06129 |
3-hydroxyacyl-CoA dehydrogenase; Validated |
8-317 |
2.27e-105 |
|
3-hydroxyacyl-CoA dehydrogenase; Validated
Pssm-ID: 235706 [Multi-domain] Cd Length: 308 Bit Score: 310.05 E-value: 2.27e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 8 APGGVAVVGSGLIGRSWAMLFASAGFRVKLFDIEPRQVTDALVSLRKEMKMLELSGYLKGElGAEEQLSLISGCSDLREA 87
Cdd:PRK06129 1 PMGSVAIIGAGLIGRAWAIVFARAGHEVRLWDADPAAAAAAPAYIAGRLEDLAAFDLLDGE-APDAVLARIRVTDSLADA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 88 VEGALHVQECVPENLELKRKLFAQLDKIADDHVILSSSSSCLLPSKLFAGLAHVKQCLVAHPVNPPYYVPLVELVPHPET 167
Cdd:PRK06129 80 VADADYVQESAPENLELKRALFAELDALAPPHAILASSTSALLASAFTEHLAGRERCLVAHPINPPYLIPVVEVVPAPWT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 168 APATVDRTYALMRRVGQSPVRLLREIDGFALNRLQYAVIAEAWRLVEEGVVSPGDLDLVMSDGLGLRYAFIGPLETMHLN 247
Cdd:PRK06129 160 APATLARAEALYRAAGQSPVRLRREIDGFVLNRLQGALLREAFRLVADGVASVDDIDAVIRDGLGLRWSFMGPFETIDLN 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 27805847 248 A-EGMLSYCDRYGEGMKRVLKTFG-PVPeFSGATAEKVHQAMCVKVPddAEHLAARRAWRDGCLMRLAQLKH 317
Cdd:PRK06129 240 ApGGVADYAQRYGPMYRRMAAERGqPVP-WDGELVARVEAERRAALP--LDQLAARQAWRDRRLMALAAHRR 308
|
|
| FadB |
COG1250 |
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA ... |
12-246 |
2.39e-68 |
|
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA dehydrogenase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440862 [Multi-domain] Cd Length: 281 Bit Score: 214.59 E-value: 2.39e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 12 VAVVGSGLIGRSWAMLFASAGFRVKLFDIEPRQVTDALVSLRKEMKMLELSGYLKGElGAEEQLSLISGCSDLrEAVEGA 91
Cdd:COG1250 5 VAVIGAGTMGAGIAAVFANAGYEVVLLDISPEALERARARIAKLLDKLVKKGKLTEE-EADAALARITPTTDL-AALADA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 92 LHVQECVPENLELKRKLFAQLDKIADDHVIlssssscllpsklFA-------------GLAHVKQCLVAHPVNPPYYVPL 158
Cdd:COG1250 83 DLVIEAVPEDLDLKQEVFAELDAVAPPDAI-------------LAsntsslsitelaaATKRPERFIGLHFFNPVPLMPL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 159 VELVPHPETAPATVDRTYALMRRVGQSPVRlLREIDGFALNRLQYAVIAEAWRLVEEGVVSPGDLDLVMSDGLGLRyafI 238
Cdd:COG1250 150 VEVIRGPATSDETVATAVAFARRLGKTPVV-VKDTPGFIVNRILVPYLNEAIRLLEEGVASPEDIDAAMRLGFGFP---M 225
|
....*...
gi 27805847 239 GPLETMHL 246
Cdd:COG1250 226 GPFELADL 233
|
|
| 3HCDH_N |
pfam02737 |
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda ... |
12-189 |
2.67e-57 |
|
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda crystallin.
Pssm-ID: 397037 [Multi-domain] Cd Length: 180 Bit Score: 183.12 E-value: 2.67e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 12 VAVVGSGLIGRSWAMLFASAGFRVKLFDIEPRQVTDALVSLRKEMKMLELSGYLKgELGAEEQLSLISGCSDLREAVeGA 91
Cdd:pfam02737 2 VAVIGAGTMGAGIAQVFALAGLEVVLVDISEEALEKALERIESSLERLVEKGRIT-EEEVDAALARISFTTDLAAAV-DA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 92 LHVQECVPENLELKRKLFAQLDKIADDHVILSSSSSCLLPSKLFAGLAHVKQCLVAHPVNPPYYVPLVELVPHPETAPAT 171
Cdd:pfam02737 80 DLVIEAVPENLELKRKLFAELDAIAPPDAILATNTSSLSITELAAATKRPERFIGLHFFNPPPLMPLVEVVRGEKTSPET 159
|
170
....*....|....*...
gi 27805847 172 VDRTYALMRRVGQSPVRL 189
Cdd:pfam02737 160 VATTVELAKKIGKTPVVV 177
|
|
| PRK06130 |
PRK06130 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
12-247 |
1.22e-50 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 235707 [Multi-domain] Cd Length: 311 Bit Score: 170.34 E-value: 1.22e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 12 VAVVGSGLIGRSWAMLFASAGFRVKLFDIEPrqvtDALVSLRKEMKMLElsGYLKGELGAEEQLSLISGCSDLREAVEGA 91
Cdd:PRK06130 7 LAIIGAGTMGSGIAALFARKGLQVVLIDVME----GALERARGVIERAL--GVYAPLGIASAGMGRIRMEAGLAAAVSGA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 92 LHVQECVPENLELKRKLFAQLDKIADDHVILSSSSSCLLPSKLFAGLAHVKQCLVAHPVNPPYYVPLVELVPHPETAPAT 171
Cdd:PRK06130 81 DLVIEAVPEKLELKRDVFARLDGLCDPDTIFATNTSGLPITAIAQAVTRPERFVGTHFFTPADVIPLVEVVRGDKTSPQT 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 27805847 172 VDRTYALMRRVGQSPVRLLREIDGFALNRLQYAVIAEAWRLVEEGVVSPGDLDLVMSDGLGLRYAFIGPLETMHLN 247
Cdd:PRK06130 161 VATTMALLRSIGKRPVLVKKDIPGFIANRIQHALAREAISLLEKGVASAEDIDEVVKWSLGIRLALTGPLEQRDMN 236
|
|
| PRK07531 |
PRK07531 |
carnitine 3-dehydrogenase; |
13-283 |
1.74e-47 |
|
carnitine 3-dehydrogenase;
Pssm-ID: 236044 [Multi-domain] Cd Length: 495 Bit Score: 166.45 E-value: 1.74e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 13 AVVGSGLIGRSWAMLFASAGFRVKLFDIEP---RQVTDALVSLRKEMKMLELSgylkgELGAEEQLSLisgCSDLREAVE 89
Cdd:PRK07531 8 ACIGGGVIGGGWAARFLLAGIDVAVFDPHPeaeRIIGEVLANAERAYAMLTDA-----PLPPEGRLTF---CASLAEAVA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 90 GALHVQECVPENLELKRKLFAQLDKIADDHVILSSSSSCLLPSKLFAGLAHVKQCLVAHPVNPPYYVPLVELVPHPETAP 169
Cdd:PRK07531 80 GADWIQESVPERLDLKRRVLAEIDAAARPDALIGSSTSGFLPSDLQEGMTHPERLFVAHPYNPVYLLPLVELVGGGKTSP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 170 ATVDRTYALMRRVGQSPVRLLREIDGFALNRLQYAVIAEAWRLVEEGVVSPGDLDLVMSDGLGLRYAFIGPLETMHLNAe 249
Cdd:PRK07531 160 ETIRRAKEILREIGMKPVHIAKEIDAFVGDRLLEALWREALWLVKDGIATTEEIDDVIRYSFGLRWAQMGLFETYRIAG- 238
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 27805847 250 gmlsycdryGE-GMKRVLKTFGP-----------VPEFSGATAEKV 283
Cdd:PRK07531 239 ---------GEaGMRHFLAQFGPclkwpwtklmdVPDLDDALVDKI 275
|
|
| PRK07066 |
PRK07066 |
L-carnitine dehydrogenase; |
13-310 |
8.36e-34 |
|
L-carnitine dehydrogenase;
Pssm-ID: 168796 [Multi-domain] Cd Length: 321 Bit Score: 126.10 E-value: 8.36e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 13 AVVGSGLIGRSWAMLFASAGFRVKLFDIEPrqvtDALVSLRKEMK----MLELSGYLKGelGAEEQLSLISgcsDLREAV 88
Cdd:PRK07066 11 AAIGSGVIGSGWVARALAHGLDVVAWDPAP----GAEAALRANVAnawpALERQGLAPG--ASPARLRFVA---TIEACV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 89 EGALHVQECVPENLELKRKLFAQLDKIADDHVILSSSSSCLLPSKLFAGLAHVKQCLVAHPVNPPYYVPLVELVPHPETA 168
Cdd:PRK07066 82 ADADFIQESAPEREALKLELHERISRAAKPDAIIASSTSGLLPTDFYARATHPERCVVGHPFNPVYLLPLVEVLGGERTA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 169 PATVDRTYALMRRVGQSPVRLLREIDGFALNRLQYAVIAEAWRLVEEGVVSPGDLDLVMSDGLGLRYAFIGPLETMHLNA 248
Cdd:PRK07066 162 PEAVDAAMGIYRALGMRPLHVRKEVPGFIADRLLEALWREALHLVNEGVATTGEIDDAIRFGAGIRWSFMGTFLTYTLAG 241
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 27805847 249 --EGMLSYCDRYGEGMKrVLKTFGPVPEFSGATAEKVhqamcvkVPDDAEHLAAR-----RAWRDGCLM 310
Cdd:PRK07066 242 gdAGMRHFMQQFGPALE-LPWTKLVAPELTDALIDRV-------VEGTAEQQGPRsikalERYRDECIT 302
|
|
| PRK08269 |
PRK08269 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
20-261 |
2.55e-33 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 181340 [Multi-domain] Cd Length: 314 Bit Score: 124.78 E-value: 2.55e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 20 IGRSWAMLFASAGFRVKLFDIEPRQVTDALVSLRKEMKMLELSGYLKGELG------AEEQLSLIS--GCSDLREAVEGA 91
Cdd:PRK08269 1 MGQGIALAFAFAGHDVTLIDFKPRDAAGWRALDAEARAEIERTLAALVALGridaaqADAVLARIAvvARDGAADALADA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 92 LHVQECVPENLELKRKLFAQLDKIADDHVILSSSSSCLLPSKLFAGLAHVKQCLVAHPVNPPYYVPLVELVPHPETAPAT 171
Cdd:PRK08269 81 DLVFEAVPEVLDAKREALRWLGRHVDADAIIASTTSTFLVTDLQRHVAHPERFLNAHWLNPAYLMPLVEVSPSDATDPAV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 172 VDRTYALMRRVGQSPVrLLREIDGFALNRLQYAVIAEAWRLVEEGVVSPGDLDLVMSDGLGLRYAFIGPLETMHLNAEGM 251
Cdd:PRK08269 161 VDRLAALLERIGKVPV-VCGPSPGYIVPRIQALAMNEAARMVEEGVASAEDIDKAIRTGFGLRFAVLGLLEFIDWGGCDI 239
|
250
....*....|
gi 27805847 252 LSYCDRYGEG 261
Cdd:PRK08269 240 LYYASRYLAG 249
|
|
| PRK08268 |
PRK08268 |
3-hydroxy-acyl-CoA dehydrogenase; Validated |
1-246 |
1.39e-31 |
|
3-hydroxy-acyl-CoA dehydrogenase; Validated
Pssm-ID: 236211 [Multi-domain] Cd Length: 507 Bit Score: 123.42 E-value: 1.39e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 1 MASPGSSAPggVAVVGSGLIGRSWAMLFASAGFRVKLFDIEPRQVTDALVSLRKEM-KMLElsgylKGELGAEE---QLS 76
Cdd:PRK08268 1 MMALPSIAT--VAVIGAGAMGAGIAQVAAQAGHTVLLYDARAGAAAAARDGIAARLaKLVE-----KGKLTAEQadaALA 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 77 LISGCSDLREAVEGALhVQECVPENLELKRKLFAQLDKIADDHVILSSSSSCLLPSKLFAGLAHVKQclVA--HPVNPpy 154
Cdd:PRK08268 74 RLRPVEALADLADCDL-VVEAIVERLDVKQALFAQLEAIVSPDCILATNTSSLSITAIAAALKHPER--VAglHFFNP-- 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 155 yVPL---VELVPHPETAPATVDRTYALMRRVGQSPVRLlREIDGFALNRLQYAVIAEAWRLVEEGVVSPGDLDLVMSDGL 231
Cdd:PRK08268 149 -VPLmklVEVVSGLATDPAVADALYALARAWGKTPVRA-KDTPGFIVNRAARPYYTEALRVLEEGVADPATIDAILREAA 226
|
250
....*....|....*
gi 27805847 232 GLRyafIGPLETMHL 246
Cdd:PRK08268 227 GFR---MGPFELMDL 238
|
|
| PRK09260 |
PRK09260 |
3-hydroxyacyl-CoA dehydrogenase; |
12-242 |
1.17e-28 |
|
3-hydroxyacyl-CoA dehydrogenase;
Pssm-ID: 236434 [Multi-domain] Cd Length: 288 Bit Score: 111.81 E-value: 1.17e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 12 VAVVGSGLIGRSWAMLFASAGFRVKLFDIEPRQvtdaLVSLRKEMKMLELSGYLKGELGAEEQLSLISGCS---DLREAV 88
Cdd:PRK09260 4 LVVVGAGVMGRGIAYVFAVSGFQTTLVDIKQEQ----LESAQQEIASIFEQGVARGKLTEAARQAALARLSyslDLKAAV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 89 EGALHVQECVPENLELKRKLFAQLDKIADDHVILSSSSSCLLPSKLFAGLAHVKQCLVAHPVNPPYYVPLVELVPHPETA 168
Cdd:PRK09260 80 ADADLVIEAVPEKLELKKAVFETADAHAPAECYIATNTSTMSPTEIASFTKRPERVIAMHFFNPVHKMKLVELIRGLETS 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 27805847 169 PATVDRTYALMRRVGQSPVrLLREIDGFALNRLQYAVIAEAWRLVEEGVVSPGDLDLVMSdgLGLRYAfIGPLE 242
Cdd:PRK09260 160 DETVQVAKEVAEQMGKETV-VVNEFPGFVTSRISALVGNEAFYMLQEGVATAEDIDKAIR--LGLNFP-MGPLE 229
|
|
| PLN02545 |
PLN02545 |
3-hydroxybutyryl-CoA dehydrogenase |
12-242 |
4.78e-27 |
|
3-hydroxybutyryl-CoA dehydrogenase
Pssm-ID: 215300 [Multi-domain] Cd Length: 295 Bit Score: 107.51 E-value: 4.78e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 12 VAVVGSGLIGRSWAMLFASAGFRVKLFDIEPRQVTDALVSLRKEMKMLELSGYLKGElGAEEQLSLISGCSDLrEAVEGA 91
Cdd:PLN02545 7 VGVVGAGQMGSGIAQLAAAAGMDVWLLDSDPAALSRGLDSISSSLARLVKKGKMSQE-EADATLGRIRCTTNL-EELRDA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 92 LHVQECVPENLELKRKLFAQLDKIADDHVILSSSSSCLLPSKLFAGLAHVKQCLVAHPVNPPYYVPLVELVPHPETAPAT 171
Cdd:PLN02545 85 DFIIEAIVESEDLKKKLFSELDRICKPSAILASNTSSISITRLASATQRPQQVIGMHFMNPPPIMKLVEIIRGADTSDEV 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 27805847 172 VDRTYALMRRVGQSPVrLLREIDGFALNRLQYAVIAEAWRLVEEGVVSPGDLDLVMSDGLGLRyafIGPLE 242
Cdd:PLN02545 165 FDATKALAERFGKTVV-CSQDYPGFIVNRILMPMINEAFYALYTGVASKEDIDTGMKLGTNHP---MGPLH 231
|
|
| PRK05808 |
PRK05808 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
12-241 |
5.17e-26 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 180269 [Multi-domain] Cd Length: 282 Bit Score: 104.27 E-value: 5.17e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 12 VAVVGSGLIGRSWAMLFASAGFRVKLFDIEPRQVTDALVSLRKEMKMLELsgylKGELGAEEQ---LSLISGCSDLREAV 88
Cdd:PRK05808 6 IGVIGAGTMGNGIAQVCAVAGYDVVMVDISDAAVDRGLATITKSLDRLVK----KGKMTEADKeaaLARITGTTDLDDLK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 89 EGALhVQECVPENLELKRKLFAQLDKIADDHVILSSSSSCLLPSKLFAGLAHVKQCLVAHPVNPPYYVPLVELVPHPETA 168
Cdd:PRK05808 82 DADL-VIEAATENMDLKKKIFAQLDEIAKPEAILATNTSSLSITELAAATKRPDKVIGMHFFNPVPVMKLVEIIRGLATS 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 27805847 169 PATVDRTYALMRRVGQSPVRlLREIDGFALNRLQYAVIAEAWRLVEEGVVSPGDLDLVMSdgLGLRYAfIGPL 241
Cdd:PRK05808 161 DATHEAVEALAKKIGKTPVE-VKNAPGFVVNRILIPMINEAIFVLAEGVATAEDIDEGMK--LGCNHP-IGPL 229
|
|
| PRK08293 |
PRK08293 |
3-hydroxyacyl-CoA dehydrogenase; |
12-244 |
4.97e-23 |
|
3-hydroxyacyl-CoA dehydrogenase;
Pssm-ID: 181359 [Multi-domain] Cd Length: 287 Bit Score: 96.55 E-value: 4.97e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 12 VAVVGSGLIGRSWAMLFASAGFRVKLFDIEPRQVTDALVSLRKEMKMLELSGYLKGELGAEEQLSLISGCSDLREAVEGA 91
Cdd:PRK08293 6 VTVAGAGVLGSQIAFQTAFHGFDVTIYDISDEALEKAKERIAKLADRYVRDLEATKEAPAEAALNRITLTTDLAEAVKDA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 92 LHVQECVPENLELKRKLFAQLDKIADDHVIlssssscllpsklFAG---------LAHV----KQCLVAHPVNPPYYVPL 158
Cdd:PRK08293 86 DLVIEAVPEDPEIKGDFYEELAKVAPEKTI-------------FATnsstllpsqFAEAtgrpEKFLALHFANEIWKNNT 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 159 VELVPHPETAPATVDRTYALMRRVGQSPVRLLREIDGFALNRLQYAVIAEAWRLVEEGVVSPGDLDLVMSDGLGlryAFI 238
Cdd:PRK08293 153 AEIMGHPGTDPEVFDTVVAFAKAIGMVPIVLKKEQPGYILNSLLVPFLSAALALWAKGVADPETIDKTWMIATG---APM 229
|
....*.
gi 27805847 239 GPLETM 244
Cdd:PRK08293 230 GPFGIL 235
|
|
| PRK06035 |
PRK06035 |
3-hydroxyacyl-CoA dehydrogenase; Validated |
12-246 |
6.90e-20 |
|
3-hydroxyacyl-CoA dehydrogenase; Validated
Pssm-ID: 180361 [Multi-domain] Cd Length: 291 Bit Score: 88.01 E-value: 6.90e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 12 VAVVGSGLIGRSWAMLFASAGFRVKLFDIEPRQVTDALVSLRKE----MKMLElsgylKGELGAEEQLSLIS--GCSDLR 85
Cdd:PRK06035 6 IGVVGSGVMGQGIAQVFARTGYDVTIVDVSEEILKNAMELIESGpyglRNLVE-----KGKMSEDEAKAIMAriRTSTSY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 86 EAVEGALHVQECVPENLELKRKLFAQLDKIADDHVILSSSSSCLLPSKLFAGLAHVKQCLVAHPVNPPYYVPLVELVPHP 165
Cdd:PRK06035 81 ESLSDADFIVEAVPEKLDLKRKVFAELERNVSPETIIASNTSGIMIAEIATALERKDRFIGMHWFNPAPVMKLIEVVRAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 166 ETAPATVDRTYALMRRVGQSPVRlLREIDGFALNRLQYAVIAEAWRLVEEGVVSPGDLDLVMSDGLGLRyafIGPLETMH 245
Cdd:PRK06035 161 LTSEETFNTTVELSKKIGKIPIE-VADVPGFFTTRFIEGWLLEAIRSFEIGIATIKDIDEMCKLAFGFP---MGPFELMD 236
|
.
gi 27805847 246 L 246
Cdd:PRK06035 237 I 237
|
|
| 3HCDH |
pfam00725 |
3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda ... |
195-283 |
5.58e-16 |
|
3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda crystallin. Some proteins include two copies of this domain.
Pssm-ID: 395588 [Multi-domain] Cd Length: 97 Bit Score: 72.25 E-value: 5.58e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 195 GFALNRLQYAVIAEAWRLVEEGVVSPGDLDLVMSDGLGLRYAFIGPLETMHLNAE--GMLSYCDRYGEGMKR---VLKTF 269
Cdd:pfam00725 1 GFVVNRLLAPYLNEAIRLVEEGVATPEDIDAAMRLGLGLPMGPFELSDLVGLDVGyhILEVLAEEFGDRAYRpppLLEKL 80
|
90
....*....|....
gi 27805847 270 GPVPEFSGATAEKV 283
Cdd:pfam00725 81 VEAGRLGRKTGKGF 94
|
|
| PRK07819 |
PRK07819 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
12-251 |
3.67e-14 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 181133 [Multi-domain] Cd Length: 286 Bit Score: 71.56 E-value: 3.67e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 12 VAVVGSGLIGRSWAMLFASAGFRVKLFDIEPRQVTDALVSLRKEMKMLELSGYLKgELGAEEQLSLISGCSDLREAVEGA 91
Cdd:PRK07819 8 VGVVGAGQMGAGIAEVCARAGVDVLVFETTEELATAGRNRIEKSLERAVSRGKLT-ERERDAALARLRFTTDLGDFADRQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 92 LhVQECVPENLELKRKLFAQLDKI-ADDHVILSSSSSCLLPSKLFAGLAHVKQCLVAHPVNPPYYVPLVELVPHPETAPA 170
Cdd:PRK07819 87 L-VIEAVVEDEAVKTEIFAELDKVvTDPDAVLASNTSSIPIMKLAAATKRPGRVLGLHFFNPVPVLPLVELVPTLVTSEA 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 171 TVDRTYALMRRV-GQSPVRlLREIDGFALNRLQYAVIAEAWRLVEEGVVSPGDLDLVMSDGLG-----LRYA-FIGpLET 243
Cdd:PRK07819 166 TVARAEEFASDVlGKQVVR-AQDRSGFVVNALLVPYLLSAIRMVESGFATAEDIDKAMVLGCAhpmgpLRLSdLVG-LDT 243
|
....*...
gi 27805847 244 MHLNAEGM 251
Cdd:PRK07819 244 VKAIADSM 251
|
|
| PRK07530 |
PRK07530 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
12-242 |
2.70e-11 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 181018 [Multi-domain] Cd Length: 292 Bit Score: 63.10 E-value: 2.70e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 12 VAVVGSGLIGRSWAMLFASAGFRVKLFDIEPRQVTDALVSLRKEMKMlELSgylKGELGAEEQ---LSLISGCSDLrEAV 88
Cdd:PRK07530 7 VGVIGAGQMGNGIAHVCALAGYDVLLNDVSADRLEAGLATINGNLAR-QVA---KGKISEEARaaaLARISTATDL-EDL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 89 EGALHVQECVPENLELKRKLFAQLDKIADDHVILSS---------SSSCLLPSKLFAGLahvkqclvaHPVNPpyyVP-- 157
Cdd:PRK07530 82 ADCDLVIEAATEDETVKRKIFAQLCPVLKPEAILATntssisitrLASATDRPERFIGI---------HFMNP---VPvm 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 158 -LVELVPHPETAPATVDRTYALMRRVGQSPVrLLREIDGFALNRLQYAVIAEAWRLVEEGVVSPGDLDLVMSdgLGLRYA 236
Cdd:PRK07530 150 kLVELIRGIATDEATFEAAKEFVTKLGKTIT-VAEDFPAFIVNRILLPMINEAIYTLYEGVGSVEAIDTAMK--LGANHP 226
|
....*.
gi 27805847 237 fIGPLE 242
Cdd:PRK07530 227 -MGPLE 231
|
|
| fadJ |
PRK11154 |
fatty acid oxidation complex subunit alpha FadJ; |
12-217 |
5.08e-11 |
|
fatty acid oxidation complex subunit alpha FadJ;
Pssm-ID: 236864 [Multi-domain] Cd Length: 708 Bit Score: 63.38 E-value: 5.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 12 VAVVGSGLIGRSWAMLFAS-AGFRVKLFDIEPRQVTDALVSL---------RKEMKMLELsgylkgelgaEEQLSLISGC 81
Cdd:PRK11154 312 VGVLGGGLMGGGIAYVTATkAGLPVRIKDINPQGINHALKYSwdlldkkvkRRHLKPSER----------DKQMALISGT 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 82 SDLReAVEGALHVQECVPENLELKRKLFAQLDKIADDHVILSSSSSCLLPSKLFAGLAHVKQCLVAHPVNPPYYVPLVEL 161
Cdd:PRK11154 382 TDYR-GFKHADVVIEAVFEDLALKQQMVAEVEQNCAPHTIFASNTSSLPIGQIAAAAARPEQVIGLHYFSPVEKMPLVEV 460
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 27805847 162 VPHPETAPATVDRTYALMRRVGQSPVrLLREIDGFALNRLQYAVIAEAWRLVEEGV 217
Cdd:PRK11154 461 IPHAKTSAETIATTVALAKKQGKTPI-VVRDGAGFYVNRILAPYINEAARLLLEGE 515
|
|
| fa_ox_alpha_mit |
TIGR02441 |
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ... |
12-224 |
2.44e-08 |
|
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).
Pssm-ID: 131494 [Multi-domain] Cd Length: 737 Bit Score: 55.23 E-value: 2.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 12 VAVVGSGLIGRSWAMLFASAGFRVKLFDIEP----RQVTDALVSLRKEMKMLELSGYLKgelgaEEQLSLISGCSDLrEA 87
Cdd:TIGR02441 338 LAVLGAGLMGAGIAQVSVDKGLKTVLKDATPagldRGQQQVFKGLNKKVKRKKITSLER-----DSILSNLTPTLDY-SG 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 88 VEGALHVQECVPENLELKRKLFAQLDKIADDHVILSSSSSCLLPSKLFAGLAHVKQCLVAHPVNPPYYVPLVELVPHPET 167
Cdd:TIGR02441 412 FKNADMVIEAVFEDLSLKHKVIKEVEAVVPPHCIIASNTSALPIKDIAAVSSRPEKVIGMHYFSPVDKMQLLEIITHDGT 491
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 27805847 168 APATVDRTYALMRRVGQSpVRLLREIDGFALNRLQYAVIAEAWRLVEEGvVSPGDLD 224
Cdd:TIGR02441 492 SKDTLASAVAVGLKQGKV-VIVVKDGPGFYTTRCLGPMLAEVIRLLQEG-VDPKKLD 546
|
|
| PRK08268 |
PRK08268 |
3-hydroxy-acyl-CoA dehydrogenase; Validated |
157-242 |
5.81e-04 |
|
3-hydroxy-acyl-CoA dehydrogenase; Validated
Pssm-ID: 236211 [Multi-domain] Cd Length: 507 Bit Score: 41.37 E-value: 5.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 157 PLVELVPHPETAPATVDRTYALMRRVGQsPVRLLREIDGFALNRLQYAVIAEAWRLVEEGVVSPGDLDLVMSdgLGLRYA 236
Cdd:PRK08268 379 KRRTLMAAPATSPAARDAAHALFQQDGK-AVSVIRDSPGFVAQRTVAMIVNEAADIAQQGIASPADIDLAMR--LGLNYP 455
|
....*.
gi 27805847 237 FiGPLE 242
Cdd:PRK08268 456 L-GPLA 460
|
|
| NAD_Gly3P_dh_N |
pfam01210 |
NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; NAD-dependent ... |
12-91 |
6.67e-03 |
|
NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase (GPDH) catalyzes the interconversion of dihydroxyacetone phosphate and L-glycerol-3-phosphate. This family represents the N-terminal NAD-binding domain.
Pssm-ID: 395967 [Multi-domain] Cd Length: 158 Bit Score: 36.79 E-value: 6.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27805847 12 VAVVGSGLIGRSWAMLFASAGFRVKLFDIEPrQVTDALVSLRkemkmlELSGYLKGELGAEEqlslISGCSDLREAVEGA 91
Cdd:pfam01210 2 IAVLGAGSWGTALAKVLADNGHEVRLWGRDE-ELIEEINTTH------ENVRYLPGIKLPEN----LKATTDLAEALKGA 70
|
|
| |
