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Concise Results
Standard Results
Full Results
urocanate hydratase isoform 1 [Homo sapiens]
Protein Classification
HutU family protein ( domain architecture ID 10006832 )
HutU family protein
List of domain hits
Name
Accession
Description
Interval
E-value
HutU
COG2987 Urocanate hydratase [Amino acid transport and metabolism];
68-669
0e+00
Urocanate hydratase [Amino acid transport and metabolism];
Pssm-ID: 442226 [Multi-domain]
Cd Length: 567
Bit Score: 879.05
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 68 LQL YG H IY M YRF C P DI E M RA Y P IEQY P CQTKVAA A IMH M I MNNLDP A VA QF P Q ELV T YGG N G QVFS NWAQ FW L TMF YL SK 147
Cdd:COG2987 1 MTT YG R IY G YRF R P ER E I RA P P GTEL P AKGWQQE A ALR M L MNNLDP E VA EH P E ELV V YGG T G RAAR NWAQ YD L IVK YL KE 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 148 MTEEQ TL VMY SG H P L G L F PSSRS APR LV I T N GMVI PN YSSRTEY E K L F ALG V TMYGQMTAGS YC YIGPQGIV H GT VL T VL 227
Cdd:COG2987 81 LEDDE TL LVQ SG K P V G V F RTHPD APR VL I A N SNLV PN WANWEDF E E L E ALG L TMYGQMTAGS WI YIGPQGIV Q GT YE T FA 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 228 NAAR RYL G i E DLAGK V F V T S GLGGM S GAQ AK AA VIV G CI G V IAEVD KAAL EKR HR QG W L M EV T D S LD RCIQ R LR EA RK KK 307
Cdd:COG2987 161 NAAR KHF G - G DLAGK L F L T A GLGGM G GAQ PL AA TMA G GV G L IAEVD PSRI EKR LE QG Y L D EV A D D LD EALA R AK EA KA KK 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 308 E V LS L G YH GN VVALWER LV HE ldttg ECLV DL GS DQTS C H N P F N g GY Y P VQ LSF T EA QS L M A SN P AV FK D LV Q ES LR R Q V 387
Cdd:COG2987 240 E P LS I G LL GN AADVLPE LV RR ----- GIVP DL VT DQTS A H D P L N - GY L P AG LSF E EA NE L R A ED P EE FK E LV K ES MA R H V 313
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 388 S A INRLAEEKFF F W DYGN AFLL EA QR AG AD vekkgagr TE F RY P SY V QHIMGDI F SQ G F GPFRWV CT SGDP Q D LAV TDE L 467
Cdd:COG2987 314 E A MLEFQARGAY F F DYGN NIRQ EA YD AG VK -------- DA F DF P GF V PAYIRPL F CY G K GPFRWV AL SGDP E D IYK TDE A 385
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 468 A TSVLE eaiadgvkvsvkl Q YM D NI RWIR E A ARHR L VV G SQ ARI LYSDQKG R VA IA V A I N QAIACRRI KAP V V LS RDH H D 547
Cdd:COG2987 386 A LELFP ------------- Q DR D LH RWIR M A RENV L FQ G LP ARI CWLGYGE R AK IA L A F N EMVRKGEL KAP I V IG RDH L D 452
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 548 V SGTD SP F RET S N IY DGS AFC AD MAVQ N FV G DAC RGATWV A LH N GGGVG W G EV I NG GF GL V L DG TP EA EG R ARLM L SW D V 627
Cdd:COG2987 453 V GSVA SP N RET E N MK DGS DAV AD WPLL N AL G NTA RGATWV S LH H GGGVG I G YS I HA GF VI V A DG SE EA DE R LKRV L TN D P 532
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 21389467 628 SN GVAR RCWS G NQK A Y E iicq T MQ E NS tlv VTLP HK V E DE RV 669
Cdd:COG2987 533 GM GVAR HADA G YEE A I E ---- T AK E RG --- VTLP ML V D DE LL 567
Name
Accession
Description
Interval
E-value
HutU
COG2987 Urocanate hydratase [Amino acid transport and metabolism];
68-669
0e+00
Urocanate hydratase [Amino acid transport and metabolism];
Pssm-ID: 442226 [Multi-domain]
Cd Length: 567
Bit Score: 879.05
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 68 LQL YG H IY M YRF C P DI E M RA Y P IEQY P CQTKVAA A IMH M I MNNLDP A VA QF P Q ELV T YGG N G QVFS NWAQ FW L TMF YL SK 147
Cdd:COG2987 1 MTT YG R IY G YRF R P ER E I RA P P GTEL P AKGWQQE A ALR M L MNNLDP E VA EH P E ELV V YGG T G RAAR NWAQ YD L IVK YL KE 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 148 MTEEQ TL VMY SG H P L G L F PSSRS APR LV I T N GMVI PN YSSRTEY E K L F ALG V TMYGQMTAGS YC YIGPQGIV H GT VL T VL 227
Cdd:COG2987 81 LEDDE TL LVQ SG K P V G V F RTHPD APR VL I A N SNLV PN WANWEDF E E L E ALG L TMYGQMTAGS WI YIGPQGIV Q GT YE T FA 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 228 NAAR RYL G i E DLAGK V F V T S GLGGM S GAQ AK AA VIV G CI G V IAEVD KAAL EKR HR QG W L M EV T D S LD RCIQ R LR EA RK KK 307
Cdd:COG2987 161 NAAR KHF G - G DLAGK L F L T A GLGGM G GAQ PL AA TMA G GV G L IAEVD PSRI EKR LE QG Y L D EV A D D LD EALA R AK EA KA KK 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 308 E V LS L G YH GN VVALWER LV HE ldttg ECLV DL GS DQTS C H N P F N g GY Y P VQ LSF T EA QS L M A SN P AV FK D LV Q ES LR R Q V 387
Cdd:COG2987 240 E P LS I G LL GN AADVLPE LV RR ----- GIVP DL VT DQTS A H D P L N - GY L P AG LSF E EA NE L R A ED P EE FK E LV K ES MA R H V 313
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 388 S A INRLAEEKFF F W DYGN AFLL EA QR AG AD vekkgagr TE F RY P SY V QHIMGDI F SQ G F GPFRWV CT SGDP Q D LAV TDE L 467
Cdd:COG2987 314 E A MLEFQARGAY F F DYGN NIRQ EA YD AG VK -------- DA F DF P GF V PAYIRPL F CY G K GPFRWV AL SGDP E D IYK TDE A 385
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 468 A TSVLE eaiadgvkvsvkl Q YM D NI RWIR E A ARHR L VV G SQ ARI LYSDQKG R VA IA V A I N QAIACRRI KAP V V LS RDH H D 547
Cdd:COG2987 386 A LELFP ------------- Q DR D LH RWIR M A RENV L FQ G LP ARI CWLGYGE R AK IA L A F N EMVRKGEL KAP I V IG RDH L D 452
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 548 V SGTD SP F RET S N IY DGS AFC AD MAVQ N FV G DAC RGATWV A LH N GGGVG W G EV I NG GF GL V L DG TP EA EG R ARLM L SW D V 627
Cdd:COG2987 453 V GSVA SP N RET E N MK DGS DAV AD WPLL N AL G NTA RGATWV S LH H GGGVG I G YS I HA GF VI V A DG SE EA DE R LKRV L TN D P 532
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 21389467 628 SN GVAR RCWS G NQK A Y E iicq T MQ E NS tlv VTLP HK V E DE RV 669
Cdd:COG2987 533 GM GVAR HADA G YEE A I E ---- T AK E RG --- VTLP ML V D DE LL 567
PRK05414
PRK05414 urocanate hydratase; Provisional
74-662
0e+00
urocanate hydratase; Provisional
Pssm-ID: 235448 [Multi-domain]
Cd Length: 556
Bit Score: 788.94
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 74 IY M YRF C P DI E M RA YPIEQYPCQTKVAA A IMH M I MNNLDP A VA QF P Q ELV T YGG N G QVFS NW AQFWLTMFY L SKMTEEQ T 153
Cdd:PRK05414 1 IY G YRF R P ER E I RA PRGTELTAKGWLQE A ALR M L MNNLDP E VA ER P E ELV V YGG I G RAAR NW ECYDAIVKT L KELEDDE T 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 154 L VMY SG H P L G L F PSSRS APR LV I T N GMVI P NYSSRTEYEK L F A L G V TMYGQMTAGS YC YIG P QGIV H GT VL T VLN AAR RY 233
Cdd:PRK05414 81 L LVQ SG K P V G V F KTHPD APR VL I A N SNLV P HWANWEHFNE L E A K G L TMYGQMTAGS WI YIG S QGIV Q GT YE T FAE AAR QH 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 234 L G i E DLAG KVFV T S GLGGM S GAQ AK AA VIV G CIGVIA EVD KAALE KR H R Q G W L M E VT D S LD RCIQRLR EA RKKK E V LS L G 313
Cdd:PRK05414 161 F G - G DLAG RLVL T A GLGGM G GAQ PL AA TMA G AVCLAV EVD ESRID KR L R T G Y L D E KA D D LD EALALAE EA KAAG E P LS I G 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 314 YH GN VVALWER LV HE ldttg ECLV DL GS DQTS C H N P F N g GY Y PV QLSFT EA QS L M A SN P AV F KDLVQE S LR R Q V S A INRL 393
Cdd:PRK05414 240 LL GN AADVLPE LV RR ----- GIRP DL VT DQTS A H D P L N - GY L PV GWTLE EA AE L R A ED P EE F VKAAKA S MA R H V E A MLAF 313
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 394 AEEKFFFW DYGN AFLLE A QR AG AD vekkgagr TE F RY P SY V QHIMGDI F SQ G F GPFRWV CT SGDP Q D LAV TD ELATSVLE 473
Cdd:PRK05414 314 QARGAYVF DYGN NIRQM A FD AG VE -------- NA F DF P GF V PAYIRPL F CE G K GPFRWV AL SGDP E D IYK TD AAVKELFP 385
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 474 eaiadgvkvsvkl QYMDNI RWI RE A ARHR L VV G SQ ARI LYSDQKG R VAIAV A I N QAIACRRI KAP V V LS RDH H D VSGTD S 553
Cdd:PRK05414 386 ------------- DDEHLH RWI DM A RERI L FQ G LP ARI CWLGYGE R ARLGL A F N EMVRNGEL KAP I V IG RDH L D SGSVA S 452
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 554 P F RET SNIY DGS AFC AD MAVQ N FVGDACR GATWV A LH N GGGVG W G EV I NG GF GL V L DGT P EA EG R ARLM L SW D VSN GV A R 633
Cdd:PRK05414 453 P N RET EAMK DGS DAV AD WPLL N ALLNTAS GATWV S LH H GGGVG M G YS I HA GF VI V A DGT E EA AE R LERV L TN D PAT GV M R 532
570 580
....*....|....*....|....*....
gi 21389467 634 RCWS G nqka YEI ICQ T MQ E NS tlv V TLP H 662
Cdd:PRK05414 533 HADA G ---- YEI AIE T AK E KG --- I TLP M 554
hutU
TIGR01228 urocanate hydratase; This model represents the second of four enzymes involved in the ...
102-646
4.59e-134
urocanate hydratase; This model represents the second of four enzymes involved in the degradation of histidine to glutamate. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130295
Cd Length: 545
Bit Score: 404.99
E-value: 4.59e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 102 A IMH M I MNNLDP A VA QF P QE LV T YGG N G QVFS NW AQ F WLTMFY L SKMTEEQ TL VMY SG H P L G L F PSSRS APR LV I T N GMV 181
Cdd:TIGR01228 20 A ALR M L MNNLDP E VA ED P EN LV V YGG I G KAAR NW EA F DKIVET L KRLENDE TL LVQ SG K P V G V F KTHEN APR VL I A N SNL 99
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 182 I P NYSSRTEYEK L F A L G VT MYGQMTAGS YC YIG P QGI VH GT VL T VLNA AR RYL G i ED L A GK VFV T S GLGGM S GAQ AK A AV 261
Cdd:TIGR01228 100 V P HWADWEHFHE L E A K G LM MYGQMTAGS WI YIG T QGI LQ GT YE T FAEL AR QHF G - GS L K GK WVL T A GLGGM G GAQ PL A VT 178
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 262 IV G CIGVIA EVD KAALE KR HRQGWLM E V TDSLD RCIQ R LR EA RKKKEVL S L G YH GN VVALWER L V h ELDTT gecl V D LGS 341
Cdd:TIGR01228 179 MN G GVSIAV EVD ESRID KR LETKYCD E Q TDSLD EALA R AE EA KAEGKPI S I G LL GN AAEVLPE L L - KRGVV ---- P D VVT 253
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 342 DQTS C H N P F N g GY Y P VQLSFTE A QS L MASN P AVFKDLVQE S LRRQ V S A INRLAEEKFFFW DYGN AFLLE A QRA G A dvekk 421
Cdd:TIGR01228 254 DQTS A H D P L N - GY I P EGYTVED A DK L RQEE P EAYVKAAKQ S MAKH V R A MLAFQKQGSVTF DYGN NIRQV A KEE G V ----- 327
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 422 gag RTE F RY P SY V QHIMGDI F SQ G F GPFRWV CT SGDP Q D LAV TD ELATSVLE E aiadgvkv SVK L Q ymdni RWI RE A ARH 501
Cdd:TIGR01228 328 --- EDA F DF P GF V PAYIRPL F CR G K GPFRWV AL SGDP A D IYR TD AAVKELFP E -------- DAH L H ----- RWI DM A QER 391
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 502 RLVV G SQ ARI LYSDQKG R VAIAV AIN QAIACRRI KAPVV LS RDH H D VSGTD SP F RET SNIY DGS AFCA D MAVQ N FVGDAC 581
Cdd:TIGR01228 392 VSFQ G LP ARI CWLGYGE R AKLGL AIN EMVRSGEL KAPVV IG RDH L D AGSVA SP N RET EAMK DGS DAVS D WPLL N ALLNTA 471
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 21389467 582 R GATWV AL H N GGGVG W G EVING G FGL V L DGT P EA EG R ARLM L SW D VSN GV A R RCWS G NQK A YEII 646
Cdd:TIGR01228 472 A GATWV SF H H GGGVG M G FSLHA G MVI V A DGT D EA AE R IARV L TN D PGM GV I R HADA G YEI A IDVA 536
Urocanase_C
pfam17392 Urocanase C-terminal domain;
440-648
1.99e-120
Urocanase C-terminal domain;
Pssm-ID: 465414 [Multi-domain]
Cd Length: 196
Bit Score: 356.80
E-value: 1.99e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 440 DI F SQ GFGPFRWV CT SGDP Q D LAV TDE L A TSVLE eaiadgvkvsvkl Q YM D N IRWI RE A ARHR L VV G SQ ARI L Y SDQKG R 519
Cdd:pfam17392 1 PL F CE GFGPFRWV AL SGDP E D IYR TDE A A LELFP ------------- Q DE D L IRWI KL A RENV L FQ G LP ARI C Y LGYGE R 67
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 520 VA IA V A I N QAIACRR I K AP V V LS RDH H DV SGTD SPFRET S N IY DGS AFC AD MAVQ N FV G D A C RGATWV A LHNGGGVG W G E 599
Cdd:pfam17392 68 AK IA L A F N ELVREGE I S AP I V IG RDH L DV GSVA SPFRET E N MK DGS DAI AD WPLL N AL G N A A RGATWV S LHNGGGVG I G Y 147
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 21389467 600 V I NG GFG L V L DGT P EA EG R A R LM L S WD VS NGVAR RCWS G NQK A YEIICQ 648
Cdd:pfam17392 148 S I HA GFG M V A DGT E EA DE R L R RV L T WD PG NGVAR HADA G YEE A IDVARR 196
Name
Accession
Description
Interval
E-value
HutU
COG2987 Urocanate hydratase [Amino acid transport and metabolism];
68-669
0e+00
Urocanate hydratase [Amino acid transport and metabolism];
Pssm-ID: 442226 [Multi-domain]
Cd Length: 567
Bit Score: 879.05
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 68 LQL YG H IY M YRF C P DI E M RA Y P IEQY P CQTKVAA A IMH M I MNNLDP A VA QF P Q ELV T YGG N G QVFS NWAQ FW L TMF YL SK 147
Cdd:COG2987 1 MTT YG R IY G YRF R P ER E I RA P P GTEL P AKGWQQE A ALR M L MNNLDP E VA EH P E ELV V YGG T G RAAR NWAQ YD L IVK YL KE 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 148 MTEEQ TL VMY SG H P L G L F PSSRS APR LV I T N GMVI PN YSSRTEY E K L F ALG V TMYGQMTAGS YC YIGPQGIV H GT VL T VL 227
Cdd:COG2987 81 LEDDE TL LVQ SG K P V G V F RTHPD APR VL I A N SNLV PN WANWEDF E E L E ALG L TMYGQMTAGS WI YIGPQGIV Q GT YE T FA 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 228 NAAR RYL G i E DLAGK V F V T S GLGGM S GAQ AK AA VIV G CI G V IAEVD KAAL EKR HR QG W L M EV T D S LD RCIQ R LR EA RK KK 307
Cdd:COG2987 161 NAAR KHF G - G DLAGK L F L T A GLGGM G GAQ PL AA TMA G GV G L IAEVD PSRI EKR LE QG Y L D EV A D D LD EALA R AK EA KA KK 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 308 E V LS L G YH GN VVALWER LV HE ldttg ECLV DL GS DQTS C H N P F N g GY Y P VQ LSF T EA QS L M A SN P AV FK D LV Q ES LR R Q V 387
Cdd:COG2987 240 E P LS I G LL GN AADVLPE LV RR ----- GIVP DL VT DQTS A H D P L N - GY L P AG LSF E EA NE L R A ED P EE FK E LV K ES MA R H V 313
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 388 S A INRLAEEKFF F W DYGN AFLL EA QR AG AD vekkgagr TE F RY P SY V QHIMGDI F SQ G F GPFRWV CT SGDP Q D LAV TDE L 467
Cdd:COG2987 314 E A MLEFQARGAY F F DYGN NIRQ EA YD AG VK -------- DA F DF P GF V PAYIRPL F CY G K GPFRWV AL SGDP E D IYK TDE A 385
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 468 A TSVLE eaiadgvkvsvkl Q YM D NI RWIR E A ARHR L VV G SQ ARI LYSDQKG R VA IA V A I N QAIACRRI KAP V V LS RDH H D 547
Cdd:COG2987 386 A LELFP ------------- Q DR D LH RWIR M A RENV L FQ G LP ARI CWLGYGE R AK IA L A F N EMVRKGEL KAP I V IG RDH L D 452
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 548 V SGTD SP F RET S N IY DGS AFC AD MAVQ N FV G DAC RGATWV A LH N GGGVG W G EV I NG GF GL V L DG TP EA EG R ARLM L SW D V 627
Cdd:COG2987 453 V GSVA SP N RET E N MK DGS DAV AD WPLL N AL G NTA RGATWV S LH H GGGVG I G YS I HA GF VI V A DG SE EA DE R LKRV L TN D P 532
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 21389467 628 SN GVAR RCWS G NQK A Y E iicq T MQ E NS tlv VTLP HK V E DE RV 669
Cdd:COG2987 533 GM GVAR HADA G YEE A I E ---- T AK E RG --- VTLP ML V D DE LL 567
PRK05414
PRK05414 urocanate hydratase; Provisional
74-662
0e+00
urocanate hydratase; Provisional
Pssm-ID: 235448 [Multi-domain]
Cd Length: 556
Bit Score: 788.94
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 74 IY M YRF C P DI E M RA YPIEQYPCQTKVAA A IMH M I MNNLDP A VA QF P Q ELV T YGG N G QVFS NW AQFWLTMFY L SKMTEEQ T 153
Cdd:PRK05414 1 IY G YRF R P ER E I RA PRGTELTAKGWLQE A ALR M L MNNLDP E VA ER P E ELV V YGG I G RAAR NW ECYDAIVKT L KELEDDE T 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 154 L VMY SG H P L G L F PSSRS APR LV I T N GMVI P NYSSRTEYEK L F A L G V TMYGQMTAGS YC YIG P QGIV H GT VL T VLN AAR RY 233
Cdd:PRK05414 81 L LVQ SG K P V G V F KTHPD APR VL I A N SNLV P HWANWEHFNE L E A K G L TMYGQMTAGS WI YIG S QGIV Q GT YE T FAE AAR QH 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 234 L G i E DLAG KVFV T S GLGGM S GAQ AK AA VIV G CIGVIA EVD KAALE KR H R Q G W L M E VT D S LD RCIQRLR EA RKKK E V LS L G 313
Cdd:PRK05414 161 F G - G DLAG RLVL T A GLGGM G GAQ PL AA TMA G AVCLAV EVD ESRID KR L R T G Y L D E KA D D LD EALALAE EA KAAG E P LS I G 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 314 YH GN VVALWER LV HE ldttg ECLV DL GS DQTS C H N P F N g GY Y PV QLSFT EA QS L M A SN P AV F KDLVQE S LR R Q V S A INRL 393
Cdd:PRK05414 240 LL GN AADVLPE LV RR ----- GIRP DL VT DQTS A H D P L N - GY L PV GWTLE EA AE L R A ED P EE F VKAAKA S MA R H V E A MLAF 313
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 394 AEEKFFFW DYGN AFLLE A QR AG AD vekkgagr TE F RY P SY V QHIMGDI F SQ G F GPFRWV CT SGDP Q D LAV TD ELATSVLE 473
Cdd:PRK05414 314 QARGAYVF DYGN NIRQM A FD AG VE -------- NA F DF P GF V PAYIRPL F CE G K GPFRWV AL SGDP E D IYK TD AAVKELFP 385
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 474 eaiadgvkvsvkl QYMDNI RWI RE A ARHR L VV G SQ ARI LYSDQKG R VAIAV A I N QAIACRRI KAP V V LS RDH H D VSGTD S 553
Cdd:PRK05414 386 ------------- DDEHLH RWI DM A RERI L FQ G LP ARI CWLGYGE R ARLGL A F N EMVRNGEL KAP I V IG RDH L D SGSVA S 452
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 554 P F RET SNIY DGS AFC AD MAVQ N FVGDACR GATWV A LH N GGGVG W G EV I NG GF GL V L DGT P EA EG R ARLM L SW D VSN GV A R 633
Cdd:PRK05414 453 P N RET EAMK DGS DAV AD WPLL N ALLNTAS GATWV S LH H GGGVG M G YS I HA GF VI V A DGT E EA AE R LERV L TN D PAT GV M R 532
570 580
....*....|....*....|....*....
gi 21389467 634 RCWS G nqka YEI ICQ T MQ E NS tlv V TLP H 662
Cdd:PRK05414 533 HADA G ---- YEI AIE T AK E KG --- I TLP M 554
hutU
TIGR01228 urocanate hydratase; This model represents the second of four enzymes involved in the ...
102-646
4.59e-134
urocanate hydratase; This model represents the second of four enzymes involved in the degradation of histidine to glutamate. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130295
Cd Length: 545
Bit Score: 404.99
E-value: 4.59e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 102 A IMH M I MNNLDP A VA QF P QE LV T YGG N G QVFS NW AQ F WLTMFY L SKMTEEQ TL VMY SG H P L G L F PSSRS APR LV I T N GMV 181
Cdd:TIGR01228 20 A ALR M L MNNLDP E VA ED P EN LV V YGG I G KAAR NW EA F DKIVET L KRLENDE TL LVQ SG K P V G V F KTHEN APR VL I A N SNL 99
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 182 I P NYSSRTEYEK L F A L G VT MYGQMTAGS YC YIG P QGI VH GT VL T VLNA AR RYL G i ED L A GK VFV T S GLGGM S GAQ AK A AV 261
Cdd:TIGR01228 100 V P HWADWEHFHE L E A K G LM MYGQMTAGS WI YIG T QGI LQ GT YE T FAEL AR QHF G - GS L K GK WVL T A GLGGM G GAQ PL A VT 178
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 262 IV G CIGVIA EVD KAALE KR HRQGWLM E V TDSLD RCIQ R LR EA RKKKEVL S L G YH GN VVALWER L V h ELDTT gecl V D LGS 341
Cdd:TIGR01228 179 MN G GVSIAV EVD ESRID KR LETKYCD E Q TDSLD EALA R AE EA KAEGKPI S I G LL GN AAEVLPE L L - KRGVV ---- P D VVT 253
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 342 DQTS C H N P F N g GY Y P VQLSFTE A QS L MASN P AVFKDLVQE S LRRQ V S A INRLAEEKFFFW DYGN AFLLE A QRA G A dvekk 421
Cdd:TIGR01228 254 DQTS A H D P L N - GY I P EGYTVED A DK L RQEE P EAYVKAAKQ S MAKH V R A MLAFQKQGSVTF DYGN NIRQV A KEE G V ----- 327
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 422 gag RTE F RY P SY V QHIMGDI F SQ G F GPFRWV CT SGDP Q D LAV TD ELATSVLE E aiadgvkv SVK L Q ymdni RWI RE A ARH 501
Cdd:TIGR01228 328 --- EDA F DF P GF V PAYIRPL F CR G K GPFRWV AL SGDP A D IYR TD AAVKELFP E -------- DAH L H ----- RWI DM A QER 391
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 502 RLVV G SQ ARI LYSDQKG R VAIAV AIN QAIACRRI KAPVV LS RDH H D VSGTD SP F RET SNIY DGS AFCA D MAVQ N FVGDAC 581
Cdd:TIGR01228 392 VSFQ G LP ARI CWLGYGE R AKLGL AIN EMVRSGEL KAPVV IG RDH L D AGSVA SP N RET EAMK DGS DAVS D WPLL N ALLNTA 471
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 21389467 582 R GATWV AL H N GGGVG W G EVING G FGL V L DGT P EA EG R ARLM L SW D VSN GV A R RCWS G NQK A YEII 646
Cdd:TIGR01228 472 A GATWV SF H H GGGVG M G FSLHA G MVI V A DGT D EA AE R IARV L TN D PGM GV I R HADA G YEI A IDVA 536
Urocanase_C
pfam17392 Urocanase C-terminal domain;
440-648
1.99e-120
Urocanase C-terminal domain;
Pssm-ID: 465414 [Multi-domain]
Cd Length: 196
Bit Score: 356.80
E-value: 1.99e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 440 DI F SQ GFGPFRWV CT SGDP Q D LAV TDE L A TSVLE eaiadgvkvsvkl Q YM D N IRWI RE A ARHR L VV G SQ ARI L Y SDQKG R 519
Cdd:pfam17392 1 PL F CE GFGPFRWV AL SGDP E D IYR TDE A A LELFP ------------- Q DE D L IRWI KL A RENV L FQ G LP ARI C Y LGYGE R 67
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 520 VA IA V A I N QAIACRR I K AP V V LS RDH H DV SGTD SPFRET S N IY DGS AFC AD MAVQ N FV G D A C RGATWV A LHNGGGVG W G E 599
Cdd:pfam17392 68 AK IA L A F N ELVREGE I S AP I V IG RDH L DV GSVA SPFRET E N MK DGS DAI AD WPLL N AL G N A A RGATWV S LHNGGGVG I G Y 147
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 21389467 600 V I NG GFG L V L DGT P EA EG R A R LM L S WD VS NGVAR RCWS G NQK A YEIICQ 648
Cdd:pfam17392 148 S I HA GFG M V A DGT E EA DE R L R RV L T WD PG NGVAR HADA G YEE A IDVARR 196
Urocanase
pfam01175 Urocanase Rossmann-like domain;
214-437
1.71e-113
Urocanase Rossmann-like domain;
Pssm-ID: 460098 [Multi-domain]
Cd Length: 209
Bit Score: 339.39
E-value: 1.71e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 214 G P QGIV H GT VL T VLN AAR RYL G i E DLAGK V FVT S GLGGM S GAQ AK AA VIV G CI G VIA EVD KAAL EKR HR QG W L M EV T D S L 293
Cdd:pfam01175 1 G T QGIV Q GT YE T FAA AAR KHF G - G DLAGK L FVT A GLGGM G GAQ PL AA TMA G GV G LVV EVD PSRI EKR LE QG Y L D EV A D D L 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 294 D RCIQ R LR EA RKK KE V LS L G YH GN VVALW E R LV HE ldttg ECLV DL GS DQTS C H N P F N g GY Y P VQ L S F T EA QS L MASN P A 373
Cdd:pfam01175 80 D EALA R AK EA KAE KE P LS I G LL GN AADVL E E LV RR ----- GIIP DL VT DQTS A H D P L N - GY I P AG L T F E EA NE L RKED P E 153
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 21389467 374 VF K D LVQES LR R Q V S A INR L AEEKFF F W DYGN A F L LEA QR AG A D vekk GA grte F RY P SY V QHI 437
Cdd:pfam01175 154 KY K E LVQES MA R H V E A MLA L QARGAY F F DYGN N F R LEA KD AG V D ---- GA ---- F DF P GF V PAY 209
Urocanase_N
pfam17391 Urocanase N-terminal domain;
85-211
1.93e-78
Urocanase N-terminal domain;
Pssm-ID: 465413 [Multi-domain]
Cd Length: 127
Bit Score: 245.53
E-value: 1.93e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21389467 85 M RA YPIEQY PC QTKVAA A IMH M I MNNLDP A VA QF P Q ELV T YGGNG QVFS NWAQF W L TMF YL SKMT E E QTL VMY SG H P L GL 164
Cdd:pfam17391 1 I RA PRGTEL PC KGWQQE A ALR M L MNNLDP E VA EY P E ELV V YGGNG KAAR NWAQF D L IVK YL KELE E D QTL LVQ SG K P V GL 80
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 21389467 165 F PSSRS APR LV I T N GMVI PN YSSRTEY E K L F ALG V TMYGQMTAGS YC 211
Cdd:pfam17391 81 F RTHPD APR VL I A N SNLV PN WATWEDF E R L E ALG L TMYGQMTAGS WI 127
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
