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Conserved domains on  [gi|24644735|ref|NP_652310|]
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enhancer of yellow 2b, isoform A [Drosophila melanogaster]

Protein Classification

ENY2 family protein( domain architecture ID 10562752)

mammalian enhancer of yellow 2 (ENY2) family protein, along with its ortholog Sus1 in yeast and E(y)2 in drosophila, is involved in coupling transcription and mRNA export in yeast and metazoa, as it is a component both of the transcriptional co-activator complex SAGA and of the mRNA export complex TREX-2

Gene Ontology:  GO:0000124|GO:0070390|GO:0015031|GO:0003713

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
EnY2 pfam10163
Transcription factor e(y)2; EnY2 is a small transcription factor which is combined in a ...
 21-92 1.37e-18

Transcription factor e(y)2; EnY2 is a small transcription factor which is combined in a complex with the TAFII40 protein. The protein is conserved from paramecium to humans.


:

Pssm-ID: 462972  Cd Length: 78  Bit Score: 72.57  E-value: 1.37e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24644735   21 SQDKAALKELLHTRLVECGWHKDIKEMIRNIIMERgVDNINRDQLAAQIVPQARALVPEVVKNEMMLRVHAA 92
Cdd:pfam10163  8 SGEYERLKNLLRERLIESGWRDEVKELCKEIIREL-EDVLTFDELVEKITPKARALVPDEVKKELLQRIRAF 78
 
Name Accession Description Interval E-value
EnY2 pfam10163
Transcription factor e(y)2; EnY2 is a small transcription factor which is combined in a ...
 21-92 1.37e-18

Transcription factor e(y)2; EnY2 is a small transcription factor which is combined in a complex with the TAFII40 protein. The protein is conserved from paramecium to humans.


Pssm-ID: 462972  Cd Length: 78  Bit Score: 72.57  E-value: 1.37e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24644735   21 SQDKAALKELLHTRLVECGWHKDIKEMIRNIIMERgVDNINRDQLAAQIVPQARALVPEVVKNEMMLRVHAA 92
Cdd:pfam10163  8 SGEYERLKNLLRERLIESGWRDEVKELCKEIIREL-EDVLTFDELVEKITPKARALVPDEVKKELLQRIRAF 78
 
Name Accession Description Interval E-value
EnY2 pfam10163
Transcription factor e(y)2; EnY2 is a small transcription factor which is combined in a ...
 21-92 1.37e-18

Transcription factor e(y)2; EnY2 is a small transcription factor which is combined in a complex with the TAFII40 protein. The protein is conserved from paramecium to humans.


Pssm-ID: 462972  Cd Length: 78  Bit Score: 72.57  E-value: 1.37e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24644735   21 SQDKAALKELLHTRLVECGWHKDIKEMIRNIIMERgVDNINRDQLAAQIVPQARALVPEVVKNEMMLRVHAA 92
Cdd:pfam10163  8 SGEYERLKNLLRERLIESGWRDEVKELCKEIIREL-EDVLTFDELVEKITPKARALVPDEVKKELLQRIRAF 78
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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