NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|24651688|ref|NP_651877|]
View 

microtubule-associated Nat9, isoform A [Drosophila melanogaster]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 11447364)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.-.-
Gene Ontology:  GO:0016746|GO:0008080
SCOP:  3000403

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
9-169 5.00e-16

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 72.34  E-value: 5.00e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651688   9 ILGHRVILVPYEARHVPKYHEWMSNETLRELTASEELTLEEEHEMQRSWR---EDSDKLTFIVLDAETysrdqdeiAAMV 85
Cdd:COG1670   3 LETERLRLRPLRPEDAEALAELLNDPEVARYLPGPPYSLEEARAWLERLLadwADGGALPFAIEDKED--------GELI 74
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651688  86 GDTNLFlhqDPDSQIPTAEAEIMIAEPYaRGKGFGREAMLLMLKYAQSqpQLKLDKFEVKIDMDNAASLHLFKSFMFVET 165
Cdd:COG1670  75 GVVGLY---DIDRANRSAEIGYWLAPAY-WGKGYATEALRALLDYAFE--ELGLHRVEAEVDPDNTASIRVLEKLGFRLE 148

                ....
gi 24651688 166 RRVE 169
Cdd:COG1670 149 GTLR 152
 
Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
9-169 5.00e-16

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 72.34  E-value: 5.00e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651688   9 ILGHRVILVPYEARHVPKYHEWMSNETLRELTASEELTLEEEHEMQRSWR---EDSDKLTFIVLDAETysrdqdeiAAMV 85
Cdd:COG1670   3 LETERLRLRPLRPEDAEALAELLNDPEVARYLPGPPYSLEEARAWLERLLadwADGGALPFAIEDKED--------GELI 74
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651688  86 GDTNLFlhqDPDSQIPTAEAEIMIAEPYaRGKGFGREAMLLMLKYAQSqpQLKLDKFEVKIDMDNAASLHLFKSFMFVET 165
Cdd:COG1670  75 GVVGLY---DIDRANRSAEIGYWLAPAY-WGKGYATEALRALLDYAFE--ELGLHRVEAEVDPDNTASIRVLEKLGFRLE 148

                ....
gi 24651688 166 RRVE 169
Cdd:COG1670 149 GTLR 152
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
13-158 3.42e-14

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 66.60  E-value: 3.42e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651688    13 RVILVPYEARHVPKYHEWMSNETLRELTASEEL-TLEEEHEMQRSWREDSDK--LTFIVLDAETysrdqdeiaAMVGDTN 89
Cdd:pfam13302   1 RLLLRPLTEEDAEALFELLSDPEVMRYGVPWPLtLEEAREWLARIWAADEAErgYGWAIELKDT---------GFIGSIG 71
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24651688    90 LFLHQDPDsqiPTAEAEIMIAEPYaRGKGFGREAMLLMLKYAQSqpQLKLDKFEVKIDMDNAASLHLFK 158
Cdd:pfam13302  72 LYDIDGEP---ERAELGYWLGPDY-WGKGYATEAVRALLEYAFE--ELGLPRLVARIDPENTASRRVLE 134
 
Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
9-169 5.00e-16

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 72.34  E-value: 5.00e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651688   9 ILGHRVILVPYEARHVPKYHEWMSNETLRELTASEELTLEEEHEMQRSWR---EDSDKLTFIVLDAETysrdqdeiAAMV 85
Cdd:COG1670   3 LETERLRLRPLRPEDAEALAELLNDPEVARYLPGPPYSLEEARAWLERLLadwADGGALPFAIEDKED--------GELI 74
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651688  86 GDTNLFlhqDPDSQIPTAEAEIMIAEPYaRGKGFGREAMLLMLKYAQSqpQLKLDKFEVKIDMDNAASLHLFKSFMFVET 165
Cdd:COG1670  75 GVVGLY---DIDRANRSAEIGYWLAPAY-WGKGYATEALRALLDYAFE--ELGLHRVEAEVDPDNTASIRVLEKLGFRLE 148

                ....
gi 24651688 166 RRVE 169
Cdd:COG1670 149 GTLR 152
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
13-158 3.42e-14

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 66.60  E-value: 3.42e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651688    13 RVILVPYEARHVPKYHEWMSNETLRELTASEEL-TLEEEHEMQRSWREDSDK--LTFIVLDAETysrdqdeiaAMVGDTN 89
Cdd:pfam13302   1 RLLLRPLTEEDAEALFELLSDPEVMRYGVPWPLtLEEAREWLARIWAADEAErgYGWAIELKDT---------GFIGSIG 71
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24651688    90 LFLHQDPDsqiPTAEAEIMIAEPYaRGKGFGREAMLLMLKYAQSqpQLKLDKFEVKIDMDNAASLHLFK 158
Cdd:pfam13302  72 LYDIDGEP---ERAELGYWLGPDY-WGKGYATEAVRALLEYAFE--ELGLPRLVARIDPENTASRRVLE 134
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
57-160 2.46e-05

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 42.12  E-value: 2.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651688    57 WREDSDKLTFIVLdaetysRDQDEIAAMVGdtnlfLHQDPDSQIPTAEAEIMIAEPYaRGKGFGREAMLLMLKYAQsqpQ 136
Cdd:pfam00583  26 DWDEDASEGFFVA------EEDGELVGFAS-----LSIIDDEPPVGEIEGLAVAPEY-RGKGIGTALLQALLEWAR---E 90
                          90       100
                  ....*....|....*....|....
gi 24651688   137 LKLDKFEVKIDMDNAASLHLFKSF 160
Cdd:pfam00583  91 RGCERIFLEVAADNLAAIALYEKL 114
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
33-169 5.28e-05

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 41.90  E-value: 5.28e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651688  33 NETLRELTASEELTLEEEHEMQRSWRE-DSDKLTFIVldAEtysrDQDEIAAMVGdtnLFLHQDPDSQIPTAEAEIMIAe 111
Cdd:COG1247  20 NEAIAEGTATFETEPPSEEEREAWFAAiLAPGRPVLV--AE----EDGEVVGFAS---LGPFRPRPAYRGTAEESIYVD- 89
                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 24651688 112 PYARGKGFGREAMLLMLKYAQSQpqlKLDKFEVKIDMDNAASLHLFKSFMFVETRRVE 169
Cdd:COG1247  90 PDARGRGIGRALLEALIERARAR---GYRRLVAVVLADNEASIALYEKLGFEEVGTLP 144
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
104-181 5.69e-04

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 37.71  E-value: 5.69e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651688 104 EAEI-MIA-EPYARGKGFGREAMLLMLKYAQSQpqlKLDKFEVKIDMDNAASLHLFKSFMFVETRRVEIF---HEVTLER 178
Cdd:COG0456  13 EAEIeDLAvDPEYRGRGIGRALLEAALERARER---GARRLRLEVREDNEAAIALYEKLGFEEVGERPNYygdDALVMEK 89

                ...
gi 24651688 179 PIT 181
Cdd:COG0456  90 ELA 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH