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Conserved domains on  [gi|24651092|ref|NP_651709|]
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CAP-D2 condensin subunit [Drosophila melanogaster]

Protein Classification

CND1 family protein( domain architecture ID 1005726)

CND1 (condensin subunit 1) family protein similar to condensin complex subunit 1, which is a regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
COG5098 super family cl34900
Chromosome condensation complex Condensin, subunit D2 [Chromatin structure and dynamics / Cell ...
85-1269 3.24e-78

Chromosome condensation complex Condensin, subunit D2 [Chromatin structure and dynamics / Cell division and chromosome partitioning];


The actual alignment was detected with superfamily member COG5098:

Pssm-ID: 227429 [Multi-domain]  Cd Length: 1128  Bit Score: 282.25  E-value: 3.24e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092   85 DLLYLTVEKLFQDLQPLLTASEPMSNQQrnsyLNLTKMTLFLQVsTVKKINNSVQQAmRDQQLNVQKKRAKpSEGLEQFP 164
Cdd:COG5098   74 KLKTSTVSDNSEDYNYLVSHNVNFTIPQ----CNLENKGRIFQL-LKSKLNSPLEVA-PSLSTNVSKLEKK-NDSANVEK 146
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  165 NWEVKRGKFLVQLFNVLQCPLEKLWSPPVAEEDFINLLCDPCYRTIELLPLrMDNKHVFDTIFQILGTSIKRFNQAMTFP 244
Cdd:COG5098  147 RDCNQMEDLLPKIVDLIRGCLSNSRETSEEMDKFLFLFLEPTKVLLERERD-SKVRSRLLECIRIYGKDVRLHNHVIDLM 225
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  245 VRILQILRGTEHAAHSVAAGILLLHEEYGISSVFSILIKSIvDALRMDSSDSSVSKHFSNFLAEFSNIAPSLIVPHLEKL 324
Cdd:COG5098  226 CTKNSNLTYFAHLSGLIAELIPSISDELNRCALKEDIPVLL-KNLSFNLPDLSGPKDISLFLNKLSELSPGIMLRQYEHF 304
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  325 AEdLLDCQSHTLRNCVLQIIGDTVVSELTSEDLSEELKEVRNEFLEHLMAHILDISAHVRSKVLSIWHHLKTQHAIPLNF 404
Cdd:COG5098  305 DE-LLDSESFTLRCCFLEICANLVEHFKKDGQMVEHYKQKLNDLVGLLVERLSDTYPYTRTKALQVLEKIFDLNSKTVGR 383
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  405 LTRVLEEAIGRLEDKSSLVRRAAMHLIKSALESNPYSSKLSIDELRAKHEHEVQAMEklNEVLEEERKQEEKLNDefssl 484
Cdd:COG5098  384 RHEVIRLVGRRLQDRSSVVRRNAIKLCSKLLMRHPFASEHGSQLRLTLWEKNLGSAE--NQLNSLKSGLQETLCD----- 456
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  485 apellpfieenltefpdmqfDKEESDETLMEriiplmreknykdvivlvrKVDFLAGNQNMSSLLKHEEHCVYVLALlkt 564
Cdd:COG5098  457 --------------------GEKEVEQDEGQ-------------------CRTELEGSFNKSAESRIENEVENINAT--- 494
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  565 yhllaagfkqSSEEMLQQIKTVQFLKDSIDFAVLMTSAFPKLHEMLMSKTNTDVFEAVDLFTTGYMFGIHGTESGMQRML 644
Cdd:COG5098  495 ----------NTSVLMKLKLMIVYYEDANQFIDIMKEIQDNISTLLFGKNKTEVNESMDFIVLCFYFRIDGSREAIKKMF 564
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  645 QLVWSSDKEKRDA-----VSDAYKRVLF-----STDQTGRAHAIKVVQNLS--KFLSEIeyghyTALESLMTEWVLGGDI 712
Cdd:COG5098  565 HLVWTKGTDDEGTsielhVLSCYKLLFQmkpnnSSLFEFAKEIARNLINLSfeASLAEL-----SSLEQLLGMMYARRYI 639
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  713 DAAVIQVLFERFTLKLEGTTSNESRLSLQLLIMASQSKSSIVSANTAIIEDIAVG-----------------ERVRRDPR 775
Cdd:COG5098  640 DKTVISELWSMYSLQKFDFSLLQASGSIIHIGMLLLVDMFHSLVGLSTLLLIGLGveglldlmlsrykciaqIRVRQRVK 719
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  776 IFTSclqllVNSIDANNTAKyykrqnsdaefvgKITRLFLDFFFHRSLYDFDALAMSVFeyfYRMCQAPDVIAQQLVTAL 855
Cdd:COG5098  720 FDDE-----INEVLAKNLAK-------------KLEHQVVDVTVSTEYSISTEQAKSAI---MLLEKLPDMLRTSLIAIS 778
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  856 LKQfneswlvkeaaaIVPSPDKADTEtvpdsqpleiphsqtltptQTQADSQSqmqgtlipVYLVSRLIFCIGYMTIKEM 935
Cdd:COG5098  779 TVG------------CFGKPHEEDSM-------------------QYLEELER--------LVKLNRLKFKVGKVAIKPL 819
                        890       900       910       920       930       940       950       960
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  936 IFLDmdiYNNMKYRDELTALEERKNRNQQAGSSHNAArltlnmsamevrkrlsgvaaepQQEPDDDLVGATAEDNIAEEI 1015
Cdd:COG5098  820 VYEE---RCEAEFKRRKISAELEENVDNDDSILNNSA----------------------QDRGESSRIGGTSEDDFVDAF 874
                        970       980       990      1000      1010      1020      1030      1040
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092 1016 HGICEDMLLYNPDALLSKLAPFIIEICKRPGEFGDPTLQQAATLALARLMTVSSRFCESNMSFLMNILNLTKNIRIKCNT 1095
Cdd:COG5098  875 FFIKEKELLYGEKSVLSNFKPVVEEGCSNSSRFSDEELQVAAYLSLYKLMCLSFEFCSEHLPLLITSMEKHPIPRIRANA 954
                       1050      1060      1070      1080      1090      1100      1110      1120
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092 1096 VVGLSDLTFRFPNIIEPWTGHFYAQLHESNTELRLTAVKMLSHLILNEMIRVKGQIADMALCIVDGNEEIRNITKQFFKE 1175
Cdd:COG5098  955 VVGLGDFLVCFNTTADEHTHYLYRRLGDEDADVRRTCLMTIHFLILAGQLKVKGQLGKMALLLTDEDAEISDMARHFFTQ 1034
                       1130      1140      1150      1160      1170      1180      1190      1200
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092 1176 IANKSNILYNVLPDIISRLGDINLNLDEDKYRIImSYILGLIQKDRQIETLVEKLCLRFPVTRVERQWRDIAYCLGLLTY 1255
Cdd:COG5098 1035 IAKKDNTMYNGFIDIFSTLSSDAENGQEPFKLII-GFLTDFISKERHQKQLKESLFLRLLRCNTQSQWDKLLCSLFNLPD 1113
                       1210
                 ....*....|....
gi 24651092 1256 NERAVKKLMDNMQH 1269
Cdd:COG5098 1114 KIAGSGGLLNRGKK 1127
 
Name Accession Description Interval E-value
COG5098 COG5098
Chromosome condensation complex Condensin, subunit D2 [Chromatin structure and dynamics / Cell ...
85-1269 3.24e-78

Chromosome condensation complex Condensin, subunit D2 [Chromatin structure and dynamics / Cell division and chromosome partitioning];


Pssm-ID: 227429 [Multi-domain]  Cd Length: 1128  Bit Score: 282.25  E-value: 3.24e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092   85 DLLYLTVEKLFQDLQPLLTASEPMSNQQrnsyLNLTKMTLFLQVsTVKKINNSVQQAmRDQQLNVQKKRAKpSEGLEQFP 164
Cdd:COG5098   74 KLKTSTVSDNSEDYNYLVSHNVNFTIPQ----CNLENKGRIFQL-LKSKLNSPLEVA-PSLSTNVSKLEKK-NDSANVEK 146
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  165 NWEVKRGKFLVQLFNVLQCPLEKLWSPPVAEEDFINLLCDPCYRTIELLPLrMDNKHVFDTIFQILGTSIKRFNQAMTFP 244
Cdd:COG5098  147 RDCNQMEDLLPKIVDLIRGCLSNSRETSEEMDKFLFLFLEPTKVLLERERD-SKVRSRLLECIRIYGKDVRLHNHVIDLM 225
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  245 VRILQILRGTEHAAHSVAAGILLLHEEYGISSVFSILIKSIvDALRMDSSDSSVSKHFSNFLAEFSNIAPSLIVPHLEKL 324
Cdd:COG5098  226 CTKNSNLTYFAHLSGLIAELIPSISDELNRCALKEDIPVLL-KNLSFNLPDLSGPKDISLFLNKLSELSPGIMLRQYEHF 304
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  325 AEdLLDCQSHTLRNCVLQIIGDTVVSELTSEDLSEELKEVRNEFLEHLMAHILDISAHVRSKVLSIWHHLKTQHAIPLNF 404
Cdd:COG5098  305 DE-LLDSESFTLRCCFLEICANLVEHFKKDGQMVEHYKQKLNDLVGLLVERLSDTYPYTRTKALQVLEKIFDLNSKTVGR 383
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  405 LTRVLEEAIGRLEDKSSLVRRAAMHLIKSALESNPYSSKLSIDELRAKHEHEVQAMEklNEVLEEERKQEEKLNDefssl 484
Cdd:COG5098  384 RHEVIRLVGRRLQDRSSVVRRNAIKLCSKLLMRHPFASEHGSQLRLTLWEKNLGSAE--NQLNSLKSGLQETLCD----- 456
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  485 apellpfieenltefpdmqfDKEESDETLMEriiplmreknykdvivlvrKVDFLAGNQNMSSLLKHEEHCVYVLALlkt 564
Cdd:COG5098  457 --------------------GEKEVEQDEGQ-------------------CRTELEGSFNKSAESRIENEVENINAT--- 494
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  565 yhllaagfkqSSEEMLQQIKTVQFLKDSIDFAVLMTSAFPKLHEMLMSKTNTDVFEAVDLFTTGYMFGIHGTESGMQRML 644
Cdd:COG5098  495 ----------NTSVLMKLKLMIVYYEDANQFIDIMKEIQDNISTLLFGKNKTEVNESMDFIVLCFYFRIDGSREAIKKMF 564
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  645 QLVWSSDKEKRDA-----VSDAYKRVLF-----STDQTGRAHAIKVVQNLS--KFLSEIeyghyTALESLMTEWVLGGDI 712
Cdd:COG5098  565 HLVWTKGTDDEGTsielhVLSCYKLLFQmkpnnSSLFEFAKEIARNLINLSfeASLAEL-----SSLEQLLGMMYARRYI 639
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  713 DAAVIQVLFERFTLKLEGTTSNESRLSLQLLIMASQSKSSIVSANTAIIEDIAVG-----------------ERVRRDPR 775
Cdd:COG5098  640 DKTVISELWSMYSLQKFDFSLLQASGSIIHIGMLLLVDMFHSLVGLSTLLLIGLGveglldlmlsrykciaqIRVRQRVK 719
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  776 IFTSclqllVNSIDANNTAKyykrqnsdaefvgKITRLFLDFFFHRSLYDFDALAMSVFeyfYRMCQAPDVIAQQLVTAL 855
Cdd:COG5098  720 FDDE-----INEVLAKNLAK-------------KLEHQVVDVTVSTEYSISTEQAKSAI---MLLEKLPDMLRTSLIAIS 778
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  856 LKQfneswlvkeaaaIVPSPDKADTEtvpdsqpleiphsqtltptQTQADSQSqmqgtlipVYLVSRLIFCIGYMTIKEM 935
Cdd:COG5098  779 TVG------------CFGKPHEEDSM-------------------QYLEELER--------LVKLNRLKFKVGKVAIKPL 819
                        890       900       910       920       930       940       950       960
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  936 IFLDmdiYNNMKYRDELTALEERKNRNQQAGSSHNAArltlnmsamevrkrlsgvaaepQQEPDDDLVGATAEDNIAEEI 1015
Cdd:COG5098  820 VYEE---RCEAEFKRRKISAELEENVDNDDSILNNSA----------------------QDRGESSRIGGTSEDDFVDAF 874
                        970       980       990      1000      1010      1020      1030      1040
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092 1016 HGICEDMLLYNPDALLSKLAPFIIEICKRPGEFGDPTLQQAATLALARLMTVSSRFCESNMSFLMNILNLTKNIRIKCNT 1095
Cdd:COG5098  875 FFIKEKELLYGEKSVLSNFKPVVEEGCSNSSRFSDEELQVAAYLSLYKLMCLSFEFCSEHLPLLITSMEKHPIPRIRANA 954
                       1050      1060      1070      1080      1090      1100      1110      1120
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092 1096 VVGLSDLTFRFPNIIEPWTGHFYAQLHESNTELRLTAVKMLSHLILNEMIRVKGQIADMALCIVDGNEEIRNITKQFFKE 1175
Cdd:COG5098  955 VVGLGDFLVCFNTTADEHTHYLYRRLGDEDADVRRTCLMTIHFLILAGQLKVKGQLGKMALLLTDEDAEISDMARHFFTQ 1034
                       1130      1140      1150      1160      1170      1180      1190      1200
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092 1176 IANKSNILYNVLPDIISRLGDINLNLDEDKYRIImSYILGLIQKDRQIETLVEKLCLRFPVTRVERQWRDIAYCLGLLTY 1255
Cdd:COG5098 1035 IAKKDNTMYNGFIDIFSTLSSDAENGQEPFKLII-GFLTDFISKERHQKQLKESLFLRLLRCNTQSQWDKLLCSLFNLPD 1113
                       1210
                 ....*....|....
gi 24651092 1256 NERAVKKLMDNMQH 1269
Cdd:COG5098 1114 KIAGSGGLLNRGKK 1127
Cnd1 pfam12717
non-SMC mitotic condensation complex subunit 1; The three non-SMC (structural maintenance of ...
1091-1250 3.93e-50

non-SMC mitotic condensation complex subunit 1; The three non-SMC (structural maintenance of chromosomes) subunits of the mitotic condensation complex are Cnd1-3. The whole complex is essential for viability and the condensing of chromosomes in mitosis.


Pssm-ID: 463677 [Multi-domain]  Cd Length: 162  Bit Score: 174.57  E-value: 3.93e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092   1091 IKCNTVVGLSdlTFRFPNIIEPWTGHFYAQLHESNTELRLTAVKMLSHLILNEMIRVKGQIADMALCIVDGNEEIRNITK 1170
Cdd:pfam12717    2 IRALAIRTMG--CIRFPNLVEYLTEPLYRRLKDEDPYVRKTAAMCVAKLILPDMVKVKGFISELAKLLEDPNPMVVANAL 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092   1171 QFFKEIANKS-NILYNVLPDIISRLGDINLNLDEDKYRIIMSYILGLIQKDRQ-IETLVEKLCLRFPVTRVERQWRDIAY 1248
Cdd:pfam12717   80 AALTEISEKDpNAIYNLLPDIISKLSDALNECSEWGQIYILDFLASYIPKDKQeAESLVEKLCPRLQHANSAVVLRAIKV 159

                   ..
gi 24651092   1249 CL 1250
Cdd:pfam12717  160 IL 161
 
Name Accession Description Interval E-value
COG5098 COG5098
Chromosome condensation complex Condensin, subunit D2 [Chromatin structure and dynamics / Cell ...
85-1269 3.24e-78

Chromosome condensation complex Condensin, subunit D2 [Chromatin structure and dynamics / Cell division and chromosome partitioning];


Pssm-ID: 227429 [Multi-domain]  Cd Length: 1128  Bit Score: 282.25  E-value: 3.24e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092   85 DLLYLTVEKLFQDLQPLLTASEPMSNQQrnsyLNLTKMTLFLQVsTVKKINNSVQQAmRDQQLNVQKKRAKpSEGLEQFP 164
Cdd:COG5098   74 KLKTSTVSDNSEDYNYLVSHNVNFTIPQ----CNLENKGRIFQL-LKSKLNSPLEVA-PSLSTNVSKLEKK-NDSANVEK 146
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  165 NWEVKRGKFLVQLFNVLQCPLEKLWSPPVAEEDFINLLCDPCYRTIELLPLrMDNKHVFDTIFQILGTSIKRFNQAMTFP 244
Cdd:COG5098  147 RDCNQMEDLLPKIVDLIRGCLSNSRETSEEMDKFLFLFLEPTKVLLERERD-SKVRSRLLECIRIYGKDVRLHNHVIDLM 225
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  245 VRILQILRGTEHAAHSVAAGILLLHEEYGISSVFSILIKSIvDALRMDSSDSSVSKHFSNFLAEFSNIAPSLIVPHLEKL 324
Cdd:COG5098  226 CTKNSNLTYFAHLSGLIAELIPSISDELNRCALKEDIPVLL-KNLSFNLPDLSGPKDISLFLNKLSELSPGIMLRQYEHF 304
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  325 AEdLLDCQSHTLRNCVLQIIGDTVVSELTSEDLSEELKEVRNEFLEHLMAHILDISAHVRSKVLSIWHHLKTQHAIPLNF 404
Cdd:COG5098  305 DE-LLDSESFTLRCCFLEICANLVEHFKKDGQMVEHYKQKLNDLVGLLVERLSDTYPYTRTKALQVLEKIFDLNSKTVGR 383
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  405 LTRVLEEAIGRLEDKSSLVRRAAMHLIKSALESNPYSSKLSIDELRAKHEHEVQAMEklNEVLEEERKQEEKLNDefssl 484
Cdd:COG5098  384 RHEVIRLVGRRLQDRSSVVRRNAIKLCSKLLMRHPFASEHGSQLRLTLWEKNLGSAE--NQLNSLKSGLQETLCD----- 456
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  485 apellpfieenltefpdmqfDKEESDETLMEriiplmreknykdvivlvrKVDFLAGNQNMSSLLKHEEHCVYVLALlkt 564
Cdd:COG5098  457 --------------------GEKEVEQDEGQ-------------------CRTELEGSFNKSAESRIENEVENINAT--- 494
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  565 yhllaagfkqSSEEMLQQIKTVQFLKDSIDFAVLMTSAFPKLHEMLMSKTNTDVFEAVDLFTTGYMFGIHGTESGMQRML 644
Cdd:COG5098  495 ----------NTSVLMKLKLMIVYYEDANQFIDIMKEIQDNISTLLFGKNKTEVNESMDFIVLCFYFRIDGSREAIKKMF 564
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  645 QLVWSSDKEKRDA-----VSDAYKRVLF-----STDQTGRAHAIKVVQNLS--KFLSEIeyghyTALESLMTEWVLGGDI 712
Cdd:COG5098  565 HLVWTKGTDDEGTsielhVLSCYKLLFQmkpnnSSLFEFAKEIARNLINLSfeASLAEL-----SSLEQLLGMMYARRYI 639
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  713 DAAVIQVLFERFTLKLEGTTSNESRLSLQLLIMASQSKSSIVSANTAIIEDIAVG-----------------ERVRRDPR 775
Cdd:COG5098  640 DKTVISELWSMYSLQKFDFSLLQASGSIIHIGMLLLVDMFHSLVGLSTLLLIGLGveglldlmlsrykciaqIRVRQRVK 719
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  776 IFTSclqllVNSIDANNTAKyykrqnsdaefvgKITRLFLDFFFHRSLYDFDALAMSVFeyfYRMCQAPDVIAQQLVTAL 855
Cdd:COG5098  720 FDDE-----INEVLAKNLAK-------------KLEHQVVDVTVSTEYSISTEQAKSAI---MLLEKLPDMLRTSLIAIS 778
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  856 LKQfneswlvkeaaaIVPSPDKADTEtvpdsqpleiphsqtltptQTQADSQSqmqgtlipVYLVSRLIFCIGYMTIKEM 935
Cdd:COG5098  779 TVG------------CFGKPHEEDSM-------------------QYLEELER--------LVKLNRLKFKVGKVAIKPL 819
                        890       900       910       920       930       940       950       960
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092  936 IFLDmdiYNNMKYRDELTALEERKNRNQQAGSSHNAArltlnmsamevrkrlsgvaaepQQEPDDDLVGATAEDNIAEEI 1015
Cdd:COG5098  820 VYEE---RCEAEFKRRKISAELEENVDNDDSILNNSA----------------------QDRGESSRIGGTSEDDFVDAF 874
                        970       980       990      1000      1010      1020      1030      1040
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092 1016 HGICEDMLLYNPDALLSKLAPFIIEICKRPGEFGDPTLQQAATLALARLMTVSSRFCESNMSFLMNILNLTKNIRIKCNT 1095
Cdd:COG5098  875 FFIKEKELLYGEKSVLSNFKPVVEEGCSNSSRFSDEELQVAAYLSLYKLMCLSFEFCSEHLPLLITSMEKHPIPRIRANA 954
                       1050      1060      1070      1080      1090      1100      1110      1120
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092 1096 VVGLSDLTFRFPNIIEPWTGHFYAQLHESNTELRLTAVKMLSHLILNEMIRVKGQIADMALCIVDGNEEIRNITKQFFKE 1175
Cdd:COG5098  955 VVGLGDFLVCFNTTADEHTHYLYRRLGDEDADVRRTCLMTIHFLILAGQLKVKGQLGKMALLLTDEDAEISDMARHFFTQ 1034
                       1130      1140      1150      1160      1170      1180      1190      1200
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092 1176 IANKSNILYNVLPDIISRLGDINLNLDEDKYRIImSYILGLIQKDRQIETLVEKLCLRFPVTRVERQWRDIAYCLGLLTY 1255
Cdd:COG5098 1035 IAKKDNTMYNGFIDIFSTLSSDAENGQEPFKLII-GFLTDFISKERHQKQLKESLFLRLLRCNTQSQWDKLLCSLFNLPD 1113
                       1210
                 ....*....|....
gi 24651092 1256 NERAVKKLMDNMQH 1269
Cdd:COG5098 1114 KIAGSGGLLNRGKK 1127
Cnd1 pfam12717
non-SMC mitotic condensation complex subunit 1; The three non-SMC (structural maintenance of ...
1091-1250 3.93e-50

non-SMC mitotic condensation complex subunit 1; The three non-SMC (structural maintenance of chromosomes) subunits of the mitotic condensation complex are Cnd1-3. The whole complex is essential for viability and the condensing of chromosomes in mitosis.


Pssm-ID: 463677 [Multi-domain]  Cd Length: 162  Bit Score: 174.57  E-value: 3.93e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092   1091 IKCNTVVGLSdlTFRFPNIIEPWTGHFYAQLHESNTELRLTAVKMLSHLILNEMIRVKGQIADMALCIVDGNEEIRNITK 1170
Cdd:pfam12717    2 IRALAIRTMG--CIRFPNLVEYLTEPLYRRLKDEDPYVRKTAAMCVAKLILPDMVKVKGFISELAKLLEDPNPMVVANAL 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092   1171 QFFKEIANKS-NILYNVLPDIISRLGDINLNLDEDKYRIIMSYILGLIQKDRQ-IETLVEKLCLRFPVTRVERQWRDIAY 1248
Cdd:pfam12717   80 AALTEISEKDpNAIYNLLPDIISKLSDALNECSEWGQIYILDFLASYIPKDKQeAESLVEKLCPRLQHANSAVVLRAIKV 159

                   ..
gi 24651092   1249 CL 1250
Cdd:pfam12717  160 IL 161
Cnd1_N pfam12922
non-SMC mitotic condensation complex subunit 1, N-term; The three non-SMC (structural ...
77-243 2.56e-39

non-SMC mitotic condensation complex subunit 1, N-term; The three non-SMC (structural maintenance of chromosomes) subunits of the mitotic condensation complex are Cnd1-3. The whole complex is essential for viability and the condensing of chromosomes in mitosis. This is the conserved N-terminus of the subunit 1.


Pssm-ID: 463750  Cd Length: 164  Bit Score: 143.87  E-value: 2.56e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092     77 AQNLMRSFDLLYLTVEKLFQDLQPLLTASEpmSNQQRNSYLNLTKMTLFLQVSTVKKINNSVQQAMRDQQLNVQKKR-AK 155
Cdd:pfam12922    1 PKLLSKLLDLLSSGLSALAESLAADLESSD--EQDDRASHKNALEMYGFLLQWLLKALEKEAASASSAAAASRGRGKkSK 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651092    156 PSEGLEQFpNWEVKRGKFLVQLFNVLQCPLEKLWSPPVAEEDFINLLCDPCYRTIElLPLRMDNKHVFDTIFQILGTSIK 235
Cdd:pfam12922   79 SKKKLESW-DWEAQRERALDLMSKVLQLDLSRLWVTTPERDTFISLFTRPCYLLLE-NEQRVKNKSIRDAIFKVLGLAVK 156

                   ....*...
gi 24651092    236 RFNQAMTF 243
Cdd:pfam12922  157 KHGHALAA 164
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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