NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|28572980|ref|NP_650659|]
View 

nicknack [Drosophila melanogaster]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
zf-AD smart00868
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 4-74 2.12e-09

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


:

Pssm-ID: 214871  Cd Length: 73  Bit Score: 53.67  E-value: 2.12e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 28572980      4 QCRLCgdLIYTQNPVNIFDENS--KMVRQIALVTGLWLTDHSKMPRNMCSCCLLSLKSAIAFRQACIKTNNRL 74
Cdd:smart00868   1 VCRLC--LSESENLVSIFDESSeaSLAEKIEECTGIEIEPDDGLPKVICGDCLEKLESFHKFRERCRESDELL 71
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 397-421 2.41e-05

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


:

Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 40.94  E-value: 2.41e-05
                          10        20
                  ....*....|....*....|....*
gi 28572980   397 FHCEVCKVSFTRNSNLKTHYRSRQH 421
Cdd:pfam12874   1 FYCELCNVTFNSESQLKSHLQGKKH 25
 
Name Accession Description Interval E-value
zf-AD smart00868
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 4-74 2.12e-09

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 214871  Cd Length: 73  Bit Score: 53.67  E-value: 2.12e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 28572980      4 QCRLCgdLIYTQNPVNIFDENS--KMVRQIALVTGLWLTDHSKMPRNMCSCCLLSLKSAIAFRQACIKTNNRL 74
Cdd:smart00868   1 VCRLC--LSESENLVSIFDESSeaSLAEKIEECTGIEIEPDDGLPKVICGDCLEKLESFHKFRERCRESDELL 71
zf-AD pfam07776
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 4-74 5.32e-08

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 462262  Cd Length: 75  Bit Score: 49.76  E-value: 5.32e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 28572980     4 QCRLCGDliYTQNPVNIFDENSK---MVRQIALVTGLWLTDHSKMPRNMCSCCLLSLKSAIAFRQACIKTNNRL 74
Cdd:pfam07776   1 VCRLCLD--ESDELIPIFDPSDSektLAEILEDCTGIELDPNDLLPKQICERCLSKLQEFYSFRERCLESQELL 72
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 397-421 2.41e-05

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 40.94  E-value: 2.41e-05
                          10        20
                  ....*....|....*....|....*
gi 28572980   397 FHCEVCKVSFTRNSNLKTHYRSRQH 421
Cdd:pfam12874   1 FYCELCNVTFNSESQLKSHLQGKKH 25
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 395-425 5.90e-04

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 37.23  E-value: 5.90e-04
                           10        20        30
                   ....*....|....*....|....*....|.
gi 28572980    395 RNFHCEVCKVSFTRNSNLKTHYRSRQHQNKL 425
Cdd:smart00451   2 GGFYCKLCNVTFTDEISVEAHLKGKKHKKNV 32
 
Name Accession Description Interval E-value
zf-AD smart00868
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 4-74 2.12e-09

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 214871  Cd Length: 73  Bit Score: 53.67  E-value: 2.12e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 28572980      4 QCRLCgdLIYTQNPVNIFDENS--KMVRQIALVTGLWLTDHSKMPRNMCSCCLLSLKSAIAFRQACIKTNNRL 74
Cdd:smart00868   1 VCRLC--LSESENLVSIFDESSeaSLAEKIEECTGIEIEPDDGLPKVICGDCLEKLESFHKFRERCRESDELL 71
zf-AD pfam07776
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 4-74 5.32e-08

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 462262  Cd Length: 75  Bit Score: 49.76  E-value: 5.32e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 28572980     4 QCRLCGDliYTQNPVNIFDENSK---MVRQIALVTGLWLTDHSKMPRNMCSCCLLSLKSAIAFRQACIKTNNRL 74
Cdd:pfam07776   1 VCRLCLD--ESDELIPIFDPSDSektLAEILEDCTGIELDPNDLLPKQICERCLSKLQEFYSFRERCLESQELL 72
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 397-421 2.41e-05

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 40.94  E-value: 2.41e-05
                          10        20
                  ....*....|....*....|....*
gi 28572980   397 FHCEVCKVSFTRNSNLKTHYRSRQH 421
Cdd:pfam12874   1 FYCELCNVTFNSESQLKSHLQGKKH 25
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 395-425 5.90e-04

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 37.23  E-value: 5.90e-04
                           10        20        30
                   ....*....|....*....|....*....|.
gi 28572980    395 RNFHCEVCKVSFTRNSNLKTHYRSRQHQNKL 425
Cdd:smart00451   2 GGFYCKLCNVTFTDEISVEAHLKGKKHKKNV 32
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH