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Conserved domains on  [gi|21356419|ref|NP_650060|]
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uncharacterized protein Dmel_CG31388, isoform A [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-AD pfam07776
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 4-76 6.38e-10

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


:

Pssm-ID: 462262  Cd Length: 75  Bit Score: 55.16  E-value: 6.38e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 21356419     4 ICRTCSRMADPAVakNLFDPSSSSV--LRQIETLTNLQLKEDGKLPRFMCQDCQHDLQIAIDFRRVCIEAQELLE 76
Cdd:pfam07776   1 VCRLCLDESDELI--PIFDPSDSEKtlAEILEDCTGIELDPNDLLPKQICERCLSKLQEFYSFRERCLESQELLQ 73
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 401-423 9.43e-03

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


:

Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 33.62  E-value: 9.43e-03
                          10        20
                  ....*....|....*....|...
gi 21356419   401 CEICRISFKTAKHYRSHLKSNAH 423
Cdd:pfam12874   3 CELCNVTFNSESQLKSHLQGKKH 25
 
Name Accession Description Interval E-value
zf-AD pfam07776
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 4-76 6.38e-10

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 462262  Cd Length: 75  Bit Score: 55.16  E-value: 6.38e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 21356419     4 ICRTCSRMADPAVakNLFDPSSSSV--LRQIETLTNLQLKEDGKLPRFMCQDCQHDLQIAIDFRRVCIEAQELLE 76
Cdd:pfam07776   1 VCRLCLDESDELI--PIFDPSDSEKtlAEILEDCTGIELDPNDLLPKQICERCLSKLQEFYSFRERCLESQELLQ 73
zf-AD smart00868
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 4-76 4.37e-09

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 214871  Cd Length: 73  Bit Score: 52.90  E-value: 4.37e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 21356419      4 ICRTCSRMADPAVakNLFDPSSSSVLRQ-IETLTNLQLKEDGKLPRFMCQDCQHDLQIAIDFRRVCIEAQELLE 76
Cdd:smart00868   1 VCRLCLSESENLV--SIFDESSEASLAEkIEECTGIEIEPDDGLPKVICGDCLEKLESFHKFRERCRESDELLR 72
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 401-423 9.43e-03

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 33.62  E-value: 9.43e-03
                          10        20
                  ....*....|....*....|...
gi 21356419   401 CEICRISFKTAKHYRSHLKSNAH 423
Cdd:pfam12874   3 CELCNVTFNSESQLKSHLQGKKH 25
 
Name Accession Description Interval E-value
zf-AD pfam07776
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 4-76 6.38e-10

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 462262  Cd Length: 75  Bit Score: 55.16  E-value: 6.38e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 21356419     4 ICRTCSRMADPAVakNLFDPSSSSV--LRQIETLTNLQLKEDGKLPRFMCQDCQHDLQIAIDFRRVCIEAQELLE 76
Cdd:pfam07776   1 VCRLCLDESDELI--PIFDPSDSEKtlAEILEDCTGIELDPNDLLPKQICERCLSKLQEFYSFRERCLESQELLQ 73
zf-AD smart00868
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 4-76 4.37e-09

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 214871  Cd Length: 73  Bit Score: 52.90  E-value: 4.37e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 21356419      4 ICRTCSRMADPAVakNLFDPSSSSVLRQ-IETLTNLQLKEDGKLPRFMCQDCQHDLQIAIDFRRVCIEAQELLE 76
Cdd:smart00868   1 VCRLCLSESENLV--SIFDESSEASLAEkIEECTGIEIEPDDGLPKVICGDCLEKLESFHKFRERCRESDELLR 72
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 401-423 9.43e-03

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 33.62  E-value: 9.43e-03
                          10        20
                  ....*....|....*....|...
gi 21356419   401 CEICRISFKTAKHYRSHLKSNAH 423
Cdd:pfam12874   3 CELCNVTFNSESQLKSHLQGKKH 25
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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