uncharacterized protein Dmel_CG6878 [Drosophila melanogaster]
Protein Classification
MGR2/ROMO1 family protein( domain architecture ID 10563009)
MGR2/ROMO1 family protein such as fungal protein MGR2 (mitochondrial genome-required protein 2) and vertebrate Reactive oxygen species modulator 1 (ROMO1)
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| Romo1 | pfam10247 | Reactive mitochondrial oxygen species modulator 1; This is a family of small, approximately ... |
14-79 | 1.83e-20 | ||
Reactive mitochondrial oxygen species modulator 1; This is a family of small, approximately 100 amino acid, proteins found from yeasts to humans. The majority of endogenous reactive oxygen species (ROS) in cells are produced by the mitochondrial respiratory chain. An increase or imbalance in ROS alters the intracellular redox homeostasis, triggers DNA damage, and may contribute to cancer development and progression. Members of this family are mitochondrial reactive oxygen species modulator 1 (Romo1) proteins that are responsible for increasing the level of ROS in cells. Increased Romo1 expression can have a number of other effects including: inducing premature senescence of cultured human fibroblasts.and increased resistance to 5-fluorouracil. : Pssm-ID: 431168 Cd Length: 66 Bit Score: 76.45 E-value: 1.83e-20
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| Name | Accession | Description | Interval | E-value | ||
| Romo1 | pfam10247 | Reactive mitochondrial oxygen species modulator 1; This is a family of small, approximately ... |
14-79 | 1.83e-20 | ||
Reactive mitochondrial oxygen species modulator 1; This is a family of small, approximately 100 amino acid, proteins found from yeasts to humans. The majority of endogenous reactive oxygen species (ROS) in cells are produced by the mitochondrial respiratory chain. An increase or imbalance in ROS alters the intracellular redox homeostasis, triggers DNA damage, and may contribute to cancer development and progression. Members of this family are mitochondrial reactive oxygen species modulator 1 (Romo1) proteins that are responsible for increasing the level of ROS in cells. Increased Romo1 expression can have a number of other effects including: inducing premature senescence of cultured human fibroblasts.and increased resistance to 5-fluorouracil. Pssm-ID: 431168 Cd Length: 66 Bit Score: 76.45 E-value: 1.83e-20
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| Name | Accession | Description | Interval | E-value | ||
| Romo1 | pfam10247 | Reactive mitochondrial oxygen species modulator 1; This is a family of small, approximately ... |
14-79 | 1.83e-20 | ||
Reactive mitochondrial oxygen species modulator 1; This is a family of small, approximately 100 amino acid, proteins found from yeasts to humans. The majority of endogenous reactive oxygen species (ROS) in cells are produced by the mitochondrial respiratory chain. An increase or imbalance in ROS alters the intracellular redox homeostasis, triggers DNA damage, and may contribute to cancer development and progression. Members of this family are mitochondrial reactive oxygen species modulator 1 (Romo1) proteins that are responsible for increasing the level of ROS in cells. Increased Romo1 expression can have a number of other effects including: inducing premature senescence of cultured human fibroblasts.and increased resistance to 5-fluorouracil. Pssm-ID: 431168 Cd Length: 66 Bit Score: 76.45 E-value: 1.83e-20
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