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Conserved domains on  [gi|21355333|ref|NP_648590|]
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uncharacterized protein Dmel_CG4069 [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
64-353 1.64e-24

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 102.93  E-value: 1.64e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333  64 PPPTPRSNFTLVchpekeeliMFGGELYTG---TKTTVYNDLFFYNTKTVEWRQLKSPSGPtPRSGHQMVAVasnGGELW 140
Cdd:COG3055   8 DLPTPRSEAAAA---------LLDGKVYVAgglSGGSASNSFEVYDPATNTWSELAPLPGP-PRHHAAAVAQ---DGKLY 74

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333 141 MFGGEHASPSQLQFhhYKDLWKFALKSRKWERIaaPNGPSPRSGHRMTVSKKRLFIFGGFHDNnqsyHYFNDVHIFSLES 220
Cdd:COG3055  75 VFGGFTGANPSSTP--LNDVYVYDPATNTWTKL--APMPTPRGGATALLLDGKIYVVGGWDDG----GNVAWVEVYDPAT 146

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333 221 YQWLKAeiggAIVPSPRSGCCIAASPEGKIYVWGGYsraamkkeadrgvthtdmfvlsqdkNAGDADNkyKWAPVKPggy 300
Cdd:COG3055 147 GTWTQL----APLPTPRDHLAAAVLPDGKILVIGGR-------------------------NGSGFSN--TWTTLAP--- 192

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|...
gi 21355333 301 KPKPRSSVGCTVaANGKAYTFGGVmdvdeddedvhGQFGDDLLAFDLTSQTWR 353
Cdd:COG3055 193 LPTARAGHAAAV-LGGKILVFGGE-----------SGFSDEVEAYDPATNTWT 233
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 423-463 9.64e-05

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


:

Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 39.86  E-value: 9.64e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 21355333   423 PSPRMNPGMCVCKGTLYIFGGIFEEDDKqlTYNDFYALDLH 463
Cdd:pfam13854   1 PVPRYGHCAVTVGDYIYLYGGYTGGEGQ--PSDDVYVLSLP 39
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
64-353 1.64e-24

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 102.93  E-value: 1.64e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333  64 PPPTPRSNFTLVchpekeeliMFGGELYTG---TKTTVYNDLFFYNTKTVEWRQLKSPSGPtPRSGHQMVAVasnGGELW 140
Cdd:COG3055   8 DLPTPRSEAAAA---------LLDGKVYVAgglSGGSASNSFEVYDPATNTWSELAPLPGP-PRHHAAAVAQ---DGKLY 74

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333 141 MFGGEHASPSQLQFhhYKDLWKFALKSRKWERIaaPNGPSPRSGHRMTVSKKRLFIFGGFHDNnqsyHYFNDVHIFSLES 220
Cdd:COG3055  75 VFGGFTGANPSSTP--LNDVYVYDPATNTWTKL--APMPTPRGGATALLLDGKIYVVGGWDDG----GNVAWVEVYDPAT 146

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333 221 YQWLKAeiggAIVPSPRSGCCIAASPEGKIYVWGGYsraamkkeadrgvthtdmfvlsqdkNAGDADNkyKWAPVKPggy 300
Cdd:COG3055 147 GTWTQL----APLPTPRDHLAAAVLPDGKILVIGGR-------------------------NGSGFSN--TWTTLAP--- 192

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|...
gi 21355333 301 KPKPRSSVGCTVaANGKAYTFGGVmdvdeddedvhGQFGDDLLAFDLTSQTWR 353
Cdd:COG3055 193 LPTARAGHAAAV-LGGKILVFGGE-----------SGFSDEVEAYDPATNTWT 233
PLN02153 PLN02153
epithiospecifier protein
 111-323 7.15e-13

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 69.63  E-value: 7.15e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333  111 EWRQL--KSPSGPTPRSGHQMVAVasnGGELWMFGGEhASPSQlqfHHYKDLWKFALKSRKWErIAAPNGPSPRS---GH 185
Cdd:PLN02153   8 GWIKVeqKGGKGPGPRCSHGIAVV---GDKLYSFGGE-LKPNE---HIDKDLYVFDFNTHTWS-IAPANGDVPRIsclGV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333  186 RMTVSKKRLFIFGGFHDNNQsyhyFNDVHIFSLESYQWL----KAEIGGaivPSPRSGCCIaASPEGKIYVWGGYSRAAM 261
Cdd:PLN02153  80 RMVAVGTKLYIFGGRDEKRE----FSDFYSYDTVKNEWTfltkLDEEGG---PEARTFHSM-ASDENHVYVFGGVSKGGL 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 21355333  262 KKEADRgvthtdmFVLSQDKNAGDAdnkyKWAPVKPGGYKPKPRSSVGCTVaANGKAYTFGG 323
Cdd:PLN02153 152 MKTPER-------FRTIEAYNIADG----KWVQLPDPGENFEKRGGAGFAV-VQGKIWVVYG 201
Kelch_4 pfam13418
Galactose oxidase, central domain;
68-118 2.98e-07

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 46.84  E-value: 2.98e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 21355333    68 PRSNFTLVCHPeKEELIMFGGElytGTKTTVYNDLFFYNTKTVEWRQLKSP 118
Cdd:pfam13418   1 PRAYHTSTSIP-DDTIYLFGGE---GEDGTLLSDLWVFDLSTNEWTRLGSL 47
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 423-463 9.64e-05

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 39.86  E-value: 9.64e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 21355333   423 PSPRMNPGMCVCKGTLYIFGGIFEEDDKqlTYNDFYALDLH 463
Cdd:pfam13854   1 PVPRYGHCAVTVGDYIYLYGGYTGGEGQ--PSDDVYVLSLP 39
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
64-353 1.64e-24

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 102.93  E-value: 1.64e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333  64 PPPTPRSNFTLVchpekeeliMFGGELYTG---TKTTVYNDLFFYNTKTVEWRQLKSPSGPtPRSGHQMVAVasnGGELW 140
Cdd:COG3055   8 DLPTPRSEAAAA---------LLDGKVYVAgglSGGSASNSFEVYDPATNTWSELAPLPGP-PRHHAAAVAQ---DGKLY 74

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333 141 MFGGEHASPSQLQFhhYKDLWKFALKSRKWERIaaPNGPSPRSGHRMTVSKKRLFIFGGFHDNnqsyHYFNDVHIFSLES 220
Cdd:COG3055  75 VFGGFTGANPSSTP--LNDVYVYDPATNTWTKL--APMPTPRGGATALLLDGKIYVVGGWDDG----GNVAWVEVYDPAT 146

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333 221 YQWLKAeiggAIVPSPRSGCCIAASPEGKIYVWGGYsraamkkeadrgvthtdmfvlsqdkNAGDADNkyKWAPVKPggy 300
Cdd:COG3055 147 GTWTQL----APLPTPRDHLAAAVLPDGKILVIGGR-------------------------NGSGFSN--TWTTLAP--- 192

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|...
gi 21355333 301 KPKPRSSVGCTVaANGKAYTFGGVmdvdeddedvhGQFGDDLLAFDLTSQTWR 353
Cdd:COG3055 193 LPTARAGHAAAV-LGGKILVFGGE-----------SGFSDEVEAYDPATNTWT 233
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
110-324 2.16e-20

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 90.99  E-value: 2.16e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333 110 VEWRQLksPSGPTPRSGHqmvAVASNGGELWMFGGEHASpsqlqfHHYKDLWKFALKSRKWERIAAPNGPsPRSGHRMTV 189
Cdd:COG3055   1 ATWSSL--PDLPTPRSEA---AAALLDGKVYVAGGLSGG------SASNSFEVYDPATNTWSELAPLPGP-PRHHAAAVA 68

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333 190 SKKRLFIFGGFHDNNQSYHYFNDVHIFSLESYQWLKaeigGAIVPSPRSGcCIAASPEGKIYVWGGYSRAAMKKEADRGV 269
Cdd:COG3055  69 QDGKLYVFGGFTGANPSSTPLNDVYVYDPATNTWTK----LAPMPTPRGG-ATALLLDGKIYVVGGWDDGGNVAWVEVYD 143

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*
gi 21355333 270 THTDmfvlsqdknagdadnkyKWAPVKPGgykPKPRSSVGCTVAANGKAYTFGGV 324
Cdd:COG3055 144 PATG-----------------TWTQLAPL---PTPRDHLAAAVLPDGKILVIGGR 178
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
64-259 6.22e-14

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 72.11  E-value: 6.22e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333  64 PPPTPRSNFTLVCHPEKeeLIMFGGELYTGTKTTVYNdlffYNTKTVEWRQLKSPsgPTPRSGHQmvAVASNGGELWMFG 143
Cdd:COG3055 107 PMPTPRGGATALLLDGK--IYVVGGWDDGGNVAWVEV----YDPATGTWTQLAPL--PTPRDHLA--AAVLPDGKILVIG 176

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333 144 GEHASPSQLQFHHYKDLwkfalksrkweriaapngPSPRSGHRMTVSKKRLFIFGGfhdnnqSYHYFNDVHIFSLESYQW 223
Cdd:COG3055 177 GRNGSGFSNTWTTLAPL------------------PTARAGHAAAVLGGKILVFGG------ESGFSDEVEAYDPATNTW 232

                       170       180       190
                ....*....|....*....|....*....|....*.
gi 21355333 224 LKAeigGAIvPSPRSGCcIAASPEGKIYVWGGYSRA 259
Cdd:COG3055 233 TAL---GEL-PTPRHGH-AAVLTDGKVYVIGGETKP 263
PLN02153 PLN02153
epithiospecifier protein
 111-323 7.15e-13

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 69.63  E-value: 7.15e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333  111 EWRQL--KSPSGPTPRSGHQMVAVasnGGELWMFGGEhASPSQlqfHHYKDLWKFALKSRKWErIAAPNGPSPRS---GH 185
Cdd:PLN02153   8 GWIKVeqKGGKGPGPRCSHGIAVV---GDKLYSFGGE-LKPNE---HIDKDLYVFDFNTHTWS-IAPANGDVPRIsclGV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333  186 RMTVSKKRLFIFGGFHDNNQsyhyFNDVHIFSLESYQWL----KAEIGGaivPSPRSGCCIaASPEGKIYVWGGYSRAAM 261
Cdd:PLN02153  80 RMVAVGTKLYIFGGRDEKRE----FSDFYSYDTVKNEWTfltkLDEEGG---PEARTFHSM-ASDENHVYVFGGVSKGGL 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 21355333  262 KKEADRgvthtdmFVLSQDKNAGDAdnkyKWAPVKPGGYKPKPRSSVGCTVaANGKAYTFGG 323
Cdd:PLN02153 152 MKTPER-------FRTIEAYNIADG----KWVQLPDPGENFEKRGGAGFAV-VQGKIWVVYG 201
PLN02153 PLN02153
epithiospecifier protein
 66-306 3.14e-10

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 61.54  E-value: 3.14e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333   66 PTPRSNFTLVCHPEKeeLIMFGGELYTGTKttVYNDLFFYNTKTVEWrQLKSPSGPTPRS---GHQMVAVasnGGELWMF 142
Cdd:PLN02153  20 PGPRCSHGIAVVGDK--LYSFGGELKPNEH--IDKDLYVFDFNTHTW-SIAPANGDVPRIsclGVRMVAV---GTKLYIF 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333  143 GGEHASPSQLQFHHY---KDLWKFALKsrkwerIAAPNGPSPRSGHRMTVSKKRLFIFGGFHDNN--QSYHYFNDVHIFS 217
Cdd:PLN02153  92 GGRDEKREFSDFYSYdtvKNEWTFLTK------LDEEGGPEARTFHSMASDENHVYVFGGVSKGGlmKTPERFRTIEAYN 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333  218 LESYQWLKaeiggaiVPSP------RSGCCIAASpEGKIYVWGGYSRAAMKKEADRGVTHTDMFVlsqDKNAGdadnkyK 291
Cdd:PLN02153 166 IADGKWVQ-------LPDPgenfekRGGAGFAVV-QGKIWVVYGFATSILPGGKSDYESNAVQFF---DPASG------K 228

                        250
                 ....*....|....*
gi 21355333  292 WAPVKPGGYKPKPRS 306
Cdd:PLN02153 229 WTEVETTGAKPSARS 243
PLN02193 PLN02193
nitrile-specifier protein
 86-362 2.31e-09

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 59.58  E-value: 2.31e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333   86 FGGELYTgtKTTVYNDLFFYNTKTVEWrQLKSPSGPTPRSGHQMVAVASNGGELWMFGGEHASpsqlqfHHYKDLWKFAL 165
Cdd:PLN02193 181 FGGEFTP--NQPIDKHLYVFDLETRTW-SISPATGDVPHLSCLGVRMVSIGSTLYVFGGRDAS------RQYNGFYSFDT 251

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333  166 KSRKWERIA-APNGPSPRSGHRMTVSKKRLFIFGGFHDNnqsyhyfndVHIFSLESY-----QWLKAEIGGAIVpSPRSG 239
Cdd:PLN02193 252 TTNEWKLLTpVEEGPTPRSFHSMAADEENVYVFGGVSAT---------ARLKTLDSYnivdkKWFHCSTPGDSF-SIRGG 321

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333  240 CCIAASpEGKIYVWGGYSRAAmkkeadrgVTHTDMFVLSQDknagdadnkyKWAPVKPGGYKPKPRsSVGCTVAANGKAY 319
Cdd:PLN02193 322 AGLEVV-QGKVWVVYGFNGCE--------VDDVHYYDPVQD----------KWTQVETFGVRPSER-SVFASAAVGKHIV 381

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 21355333  320 TFGGVMDVDEDDEDVHGQFGDDLLAFDLTSQTW-RL----QEIQTKSS 362
Cdd:PLN02193 382 IFGGEIAMDPLAHVGPGQLTDGTFALDTETLQWeRLdkfgEEEETPSS 429
PHA03098 PHA03098
kelch-like protein; Provisional
 98-257 2.15e-07

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 53.23  E-value: 2.15e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333   98 VYNDLFFYNTKTVEWrqLKSPSGPTPRSGhqmVAVASNGGELWMFGGEHASPSQLQFhhykDLWKFalKSRKWERiaAPN 177
Cdd:PHA03098 309 SVNSVVSYDTKTKSW--NKVPELIYPRKN---PGVTVFNNRIYVIGGIYNSISLNTV----ESWKP--GESKWRE--EPP 375

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333  178 GPSPRSGHRMTVSKKRLFIFGGFHDNnqsYHYFNDVHIFSLESYQWLKaeigGAIVPSPRSGCCiAASPEGKIYVWGGYS 257
Cdd:PHA03098 376 LIFPRYNPCVVNVNNLIYVIGGISKN---DELLKTVECFSLNTNKWSK----GSPLPISHYGGC-AIYHDGKIYVIGGIS 447
Kelch_4 pfam13418
Galactose oxidase, central domain;
68-118 2.98e-07

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 46.84  E-value: 2.98e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 21355333    68 PRSNFTLVCHPeKEELIMFGGElytGTKTTVYNDLFFYNTKTVEWRQLKSP 118
Cdd:pfam13418   1 PRAYHTSTSIP-DDTIYLFGGE---GEDGTLLSDLWVFDLSTNEWTRLGSL 47
Kelch_4 pfam13418
Galactose oxidase, central domain;
123-176 1.43e-06

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 44.91  E-value: 1.43e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 21355333   123 PRSGHQMVAVASngGELWMFGGEhASPSQLqfhhYKDLWKFALKSRKWERIAAP 176
Cdd:pfam13418   1 PRAYHTSTSIPD--DTIYLFGGE-GEDGTL----LSDLWVFDLSTNEWTRLGSL 47
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 179-221 4.91e-06

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 43.32  E-value: 4.91e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 21355333   179 PSPRSGHRMTVSKKRLFIFGGFHDNNQSyhYFNDVHIFSLESY 221
Cdd:pfam13854   1 PVPRYGHCAVTVGDYIYLYGGYTGGEGQ--PSDDVYVLSLPTF 41
Kelch_3 pfam13415
Galactose oxidase, central domain;
136-189 1.19e-05

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 42.66  E-value: 1.19e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 21355333   136 GGELWMFGGEHASPSQlqfhHYKDLWKFALKSRKWERIAapNGPSPRSGHRMTV 189
Cdd:pfam13415   1 GDKLYIFGGLGFDGQT----RLNDLYVYDLDTNTWTQIG--DLPPPRSGHSATY 48
Kelch_3 pfam13415
Galactose oxidase, central domain;
80-132 5.03e-05

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 40.74  E-value: 5.03e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 21355333    80 KEELIMFGGELYTGTktTVYNDLFFYNTKTVEWRQLksPSGPTPRSGHQMVAV 132
Cdd:pfam13415   1 GDKLYIFGGLGFDGQ--TRLNDLYVYDLDTNTWTQI--GDLPPPRSGHSATYI 49
Kelch_3 pfam13415
Galactose oxidase, central domain;
191-244 5.39e-05

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 40.74  E-value: 5.39e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 21355333   191 KKRLFIFGGFHDNNQSYHyfNDVHIFSLESYQWLKAeiggAIVPSPRSGCCIAA 244
Cdd:pfam13415   1 GDKLYIFGGLGFDGQTRL--NDLYVYDLDTNTWTQI----GDLPPPRSGHSATY 48
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 423-463 9.64e-05

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 39.86  E-value: 9.64e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 21355333   423 PSPRMNPGMCVCKGTLYIFGGIFEEDDKqlTYNDFYALDLH 463
Cdd:pfam13854   1 PVPRYGHCAVTVGDYIYLYGGYTGGEGQ--PSDDVYVLSLP 39
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 181-223 3.61e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 38.36  E-value: 3.61e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 21355333   181 PRSGHRMTVSKKRLFIFGGFHDNNqsyhYFNDVHIFSLESYQW 223
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGNQ----SLNSVEVYDPETNTW 39
PRK14131 PRK14131
N-acetylneuraminate epimerase;
104-214 8.72e-04

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 41.54  E-value: 8.72e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333  104 FY----NTKTVEWRQLKSPSGPtPRSGHQMVAVasnGGELWMFGGEHASPSQLQFHHYKDLWKFALKSRKWERIAApngP 179
Cdd:PRK14131  52 WYkldlNAPSKGWTKIAAFPGG-PREQAVAAFI---DGKLYVFGGIGKTNSEGSPQVFDDVYKYDPKTNSWQKLDT---R 124

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 21355333  180 SPR--SGHRMTVS-KKRLFIFGGFhdnNQSYH--YFNDVH 214
Cdd:PRK14131 125 SPVglAGHVAVSLhNGKAYITGGV---NKNIFdgYFEDLA 161
Kelch_4 pfam13418
Galactose oxidase, central domain;
425-470 1.11e-03

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 36.82  E-value: 1.11e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 21355333   425 PRMNPGMCVC-KGTLYIFGGIFEEDDkqlTYNDFYALDLHKLEWKVL 470
Cdd:pfam13418   1 PRAYHTSTSIpDDTIYLFGGEGEDGT---LLSDLWVFDLSTNEWTRL 44
Kelch_4 pfam13418
Galactose oxidase, central domain;
181-223 1.12e-03

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 36.82  E-value: 1.12e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 21355333   181 PRSGHRMT-VSKKRLFIFGGFHDNNQSYhyfNDVHIFSLESYQW 223
Cdd:pfam13418   1 PRAYHTSTsIPDDTIYLFGGEGEDGTLL---SDLWVFDLSTNEW 41
Kelch_6 pfam13964
Kelch motif;
123-179 1.29e-03

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 36.93  E-value: 1.29e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 21355333   123 PRSGHQMVAVasnGGELWMFGGEHASPSqlqfhHYKDLWKFALKSRKWERIAAPNGP 179
Cdd:pfam13964   1 PRTFHSVVSV---GGYIYVFGGYTNASP-----ALNKLEVYNPLTKSWEELPPLPTP 49
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 425-470 3.25e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 35.67  E-value: 3.25e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 21355333   425 PRMNPGMCVCKGTLYIFGGIfeedDKQLTYNDFYALDLHKLEWKVL 470
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGF----DGNQSLNSVEVYDPETNTWSKL 42
Kelch_2 pfam07646
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 181-223 4.27e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 462220 [Multi-domain]  Cd Length: 47  Bit Score: 35.39  E-value: 4.27e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 21355333   181 PRSGHRMTVSKKRLFIFGGFHDNNQSyhYFNDVHIFSLESYQW 223
Cdd:pfam07646   1 PRYPHASSVPGGKLYVVGGSDGLGDL--SSSDVLVYDPETNVW 41
PHA03098 PHA03098
kelch-like protein; Provisional
 155-324 8.53e-03

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 38.60  E-value: 8.53e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333  155 HHYKDLWKFALKSRKWERIaaPNGPSPRSGHRMTVSKKRLFIFGGFHDNNqsyhYFNDVHIFSLESYQWLKAeiggAIVP 234
Cdd:PHA03098 308 LSVNSVVSYDTKTKSWNKV--PELIYPRKNPGVTVFNNRIYVIGGIYNSI----SLNTVESWKPGESKWREE----PPLI 377

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355333  235 SPRSGCCIAaSPEGKIYVWGGYSraamkkeaDRGVTHTDMFVLSQDKNagdadnkyKWAPVKPGGYKpkprSSVGCTVAA 314
Cdd:PHA03098 378 FPRYNPCVV-NVNNLIYVIGGIS--------KNDELLKTVECFSLNTN--------KWSKGSPLPIS----HYGGCAIYH 436

                        170
                 ....*....|
gi 21355333  315 NGKAYTFGGV 324
Cdd:PHA03098 437 DGKIYVIGGI 446
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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