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Dis3 like 3'-5' exoribonuclease 2, isoform A [Drosophila melanogaster]
Protein Classification
ribonuclease R family protein ( domain architecture ID 11426128 )
ribonuclease R (RNaseR or RNR) family protein similar to RNR, a 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
List of domain hits
Name
Accession
Description
Interval
E-value
RNB
pfam00773 RNB domain; This domain is the catalytic domain of ribonuclease II.
548-897
1.47e-97
RNB domain; This domain is the catalytic domain of ribonuclease II.
Pssm-ID: 459934 [Multi-domain]
Cd Length: 314
Bit Score: 310.76
E-value: 1.47e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 548 RKDLR KMCIF TIDP MT A R DLDDA V S I EKL GDNE Y EI GVHI S DVSH FLIEDNE LD NIVKE R S TS I YL ANE VI H MLP QS L CM 627
Cdd:pfam00773 1 RKDLR DLPFI TIDP AD A K DLDDA I S V EKL PNGG Y RL GVHI A DVSH YVPPGSP LD REARK R G TS V YL PDR VI P MLP EK L SN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 628 R - CSL L PG Q D KF A F SV FWRMNGK G VM lq KKP E FCRT VI N S CSQFA YE HAQKIIDNPNE rftendfptiln GFNPD D IRNR 706
Cdd:pfam00773 81 D l CSL N PG E D RL A L SV EITIDAD G EV -- TSY E IYPS VI R S KARLT YE EVDDLLEGKDA ------------ EKDKP D LAED 146
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 707 VLW L HDI A SSI R KT RL DN GAL TINNAKLRFL LD P it GEPLSFEVEKQRE A NR LIEEFMLLAN Q AVAR FIHD s FPDI A VL R 786
Cdd:pfam00773 147 LRL L YEL A KIL R AK RL QR GAL DLDTPENKLI LD E -- EGVIDILIQERTD A HS LIEEFMLLAN E AVAR HLQE - LGIP A LY R 223
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 787 N HP P P LIKS L KA L REK L LA L GFELDY S S S KALQESMV RL cneapnpvamnac LS Q LL MKP M A RA T Y F csegkse P AD L W H 866
Cdd:pfam00773 224 V HP E P DLEK L NS L IKL L QL L PDDKGL S K S LEKIKDDE RL ------------- LS I LL LRT M P RA E Y S ------- P EP L G H 283
330 340 350
....*....|....*....|....*....|.
gi 19922976 867 YA L SIP IYTHFTSPIRRYPD IL VHR L L A A A L 897
Cdd:pfam00773 284 FG L GLD IYTHFTSPIRRYPD LI VHR Q L K A L L 314
OB_Dis3 super family
cl39334 Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 ...
442-518
8.27e-10
Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 protein. This domain along with CSD1 binds to RNA.
pfam17849 :Pssm-ID: 436091 [Multi-domain]
Cd Length: 77
Bit Score: 56.08
E-value: 8.27e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19922976 442 FYK F R P Y D L R V P MVYV P KDACAAHIGNKQQ i D VS G L L YLAH I LETDC N - GHCIAELIQPV G RV G NLDD E LK AIL FH NG 518
Cdd:pfam17849 1 YVL F V P R D K R I P RIRI P TKSAPEEFLENPE - D LE G K L FVVK I DDWPE N s RYPLGHIVKVL G EI G DIET E TE AIL LE NG 77
Name
Accession
Description
Interval
E-value
RNB
pfam00773 RNB domain; This domain is the catalytic domain of ribonuclease II.
548-897
1.47e-97
RNB domain; This domain is the catalytic domain of ribonuclease II.
Pssm-ID: 459934 [Multi-domain]
Cd Length: 314
Bit Score: 310.76
E-value: 1.47e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 548 RKDLR KMCIF TIDP MT A R DLDDA V S I EKL GDNE Y EI GVHI S DVSH FLIEDNE LD NIVKE R S TS I YL ANE VI H MLP QS L CM 627
Cdd:pfam00773 1 RKDLR DLPFI TIDP AD A K DLDDA I S V EKL PNGG Y RL GVHI A DVSH YVPPGSP LD REARK R G TS V YL PDR VI P MLP EK L SN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 628 R - CSL L PG Q D KF A F SV FWRMNGK G VM lq KKP E FCRT VI N S CSQFA YE HAQKIIDNPNE rftendfptiln GFNPD D IRNR 706
Cdd:pfam00773 81 D l CSL N PG E D RL A L SV EITIDAD G EV -- TSY E IYPS VI R S KARLT YE EVDDLLEGKDA ------------ EKDKP D LAED 146
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 707 VLW L HDI A SSI R KT RL DN GAL TINNAKLRFL LD P it GEPLSFEVEKQRE A NR LIEEFMLLAN Q AVAR FIHD s FPDI A VL R 786
Cdd:pfam00773 147 LRL L YEL A KIL R AK RL QR GAL DLDTPENKLI LD E -- EGVIDILIQERTD A HS LIEEFMLLAN E AVAR HLQE - LGIP A LY R 223
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 787 N HP P P LIKS L KA L REK L LA L GFELDY S S S KALQESMV RL cneapnpvamnac LS Q LL MKP M A RA T Y F csegkse P AD L W H 866
Cdd:pfam00773 224 V HP E P DLEK L NS L IKL L QL L PDDKGL S K S LEKIKDDE RL ------------- LS I LL LRT M P RA E Y S ------- P EP L G H 283
330 340 350
....*....|....*....|....*....|.
gi 19922976 867 YA L SIP IYTHFTSPIRRYPD IL VHR L L A A A L 897
Cdd:pfam00773 284 FG L GLD IYTHFTSPIRRYPD LI VHR Q L K A L L 314
VacB
COG0557 Exoribonuclease R [Transcription];
408-917
1.11e-94
Exoribonuclease R [Transcription];
Pssm-ID: 440323 [Multi-domain]
Cd Length: 711
Bit Score: 316.28
E-value: 1.11e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 408 P KAF V IA I TK R T e LRQI VG TISFTNP tklcddql F YKFR P Y D L R VPM - VYV P K D ACA - A HI G NK qqid V sglly LAH I LE 485
Cdd:COG0557 122 P EGR V VE I LE R A - NTRV VG RFEKEKG -------- F GFVV P D D K R LLQ d IFI P P D DLN g A KD G DL ---- V ----- VVE I TR 183
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 486 TDCNGH ciaeli Q P V GRV ---- G NLD D --- E LKAILFHN GL RDI kp F EQRFIDIYSQP P PPISQE DL RQ R K DLR KMCIF T 558
Cdd:COG0557 184 YPERRG ------ P P E GRV vevl G SPG D pga E ILIAIRKH GL PHE -- F PEEVLAEAEAL P DEVPEA DL KG R R DLR DLPLV T 255
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 559 ID PMT A R D L DDAVS I EKL GDNEYEI GVHI S DVSH FLIEDNE LD NIVKE R S TS I YL ANE VI H MLP QS L C - MR CSL L PG Q D K 637
Cdd:COG0557 256 ID GED A K D F DDAVS A EKL DNGGWRL GVHI A DVSH YVRPGSA LD REARK R G TS V YL PDR VI P MLP ER L S n GL CSL N PG E D R 335
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 638 F A F S VFWRMNG KG VM lq KKP EF C R T VI N S CSQFA YE HA Q K I I D NPN E RFT E ND fptilngfnp D D IRNRVLW L HDI A SSI 717
Cdd:COG0557 336 L A M S CEMEIDA KG EV -- VSY EF Y R S VI R S DARLT YE EV Q A I L D GKD E ELR E EY ---------- A D LVPMLEE L YEL A KIL 403
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 718 RK T R LDN GA LTINNAKLRFL LD P i T G E P LSFEVEKQRE A NR LIEEFMLLAN Q AVA R F IHDS fp DIAV L - R N H PP P LIKS L 796
Cdd:COG0557 404 RK A R EKR GA IDFDLPETKII LD E - E G K P EDIVPRERND A HK LIEEFMLLAN E AVA E F LEKL -- KLPF L y R V H EE P DPEK L 480
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 797 K ALRE K L LA LG FE L --- D YSSS K A LQ esmv R L CNEAPNPVAMNA c L SQ LL MKP M AR A T Y fcsegks E P ADLW H YA L SIPI 873
Cdd:COG0557 481 E ALRE F L AN LG LK L kgg D EPTP K D LQ ---- K L LEQVKGRPEEEL - L NT LL LRS M KQ A V Y ------- S P ENIG H FG L ALEA 548
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 19922976 874 YTHFTSPIRRYPD I LVHR L L A A A L KYCTP P KRTPDDLHT L TKL A 917
Cdd:COG0557 549 YTHFTSPIRRYPD L LVHR A L K A Y L EGKRS P GLQEYLEEE L EEI A 592
RNB
smart00955 This domain is the catalytic domain of ribonuclease II;
548-898
1.91e-92
This domain is the catalytic domain of ribonuclease II;
Pssm-ID: 214935 [Multi-domain]
Cd Length: 286
Bit Score: 296.10
E-value: 1.91e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 548 R K DLR KMCI FTIDP MT A R D L DDAVS I EKL GDNE Y EI GVHI S DVSH FLIEDNE LD NIVKE R S TS I YL ANE VI H MLP QS L CM 627
Cdd:smart00955 1 R V DLR DLPL FTIDP ED A K D I DDAVS V EKL DNGG Y RL GVHI A DVSH YVKPGSA LD REARK R G TS V YL PDR VI P MLP EE L SN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 628 - R CSL L PG Q D KF A F SV FWRMNGK G VMLQKK p EF C R T VI N S CSQFA YE HAQK I ID npnerftendfptilngfnpddirnr 706
Cdd:smart00955 81 g L CSL N PG E D RL A L SV EMTLDAD G GEILDY - EF Y R S VI R S KARLT YE EVDA I LE -------------------------- 133
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 707 vlwlhdiassirktrldngaltinnakl RFL LD P i T G EPLSFEVEKQRE A NR L I EEFM L LAN Q AVARF IHDSFPD i AVL R 786
Cdd:smart00955 134 ---------------------------- KIV LD E - E G KIEDIVPRERND A HS L V EEFM I LAN E AVARF LAKNGIP - GLY R 183
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 787 N H PP P - LI K SLKA L R E K L LA LG FE L - DYSSS KAL QESMVRLCNEAPNPV amnac L SQ LL MKP M AR A T Y FCSEGK sepadl 864
Cdd:smart00955 184 V H EG P d PE K LAEL L K E F L AL LG LL L l GGDGP KAL AKLLEKIRDSPEERL ----- L EL LL LRS M PH A E Y SVDNSG ------ 252
330 340 350
....*....|....*....|....*....|....
gi 19922976 865 w H YA L SIPI YTHFTSPIRRYPD IL VHR L L A AAL K 898
Cdd:smart00955 253 - H FG L ALDA YTHFTSPIRRYPD LI VHR Q L K AAL R 285
RNase_R
TIGR02063 ribonuclease R; This family consists of an exoribonuclease, ribonuclease R, also called VacB. ...
408-945
3.68e-82
ribonuclease R; This family consists of an exoribonuclease, ribonuclease R, also called VacB. It is one of the eight exoribonucleases reported in E. coli and is broadly distributed throughout the bacteria. In E. coli, double mutants of this protein and polynucleotide phosphorylase are not viable. Scoring between trusted and noise cutoffs to the model are shorter, divergent forms from the Chlamydiae, and divergent forms from the Campylobacterales (including Helicobacter pylori) and Leptospira interrogans. [Transcription, Degradation of RNA]
Pssm-ID: 273947 [Multi-domain]
Cd Length: 709
Bit Score: 281.85
E-value: 3.68e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 408 PK A F VI A I TK R T e LR QIVGT ISFT N PTKLC --- D DQLFYKF rpydlrvpmv YV P KDACA - A HI G N K qqidvsgll Y L AH I 483
Cdd:TIGR02063 123 FE A R VI K I LE R A - ND QIVGT FYIE N GIGFV ipd D KRIYLDI ---------- FI P PEQIL g A EE G D K --------- V L VE I 182
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 484 LE - T D C N GHC I AELIQ pvg RV G NL DD --- ELKA I LFHN G L rd IKP F EQRFI D IYSQP P PPISQ E DLRQ RKDLR KMCIF TI 559
Cdd:TIGR02063 183 TK y P D R N RPA I GKVVE --- IL G HA DD pgi DILI I IRKH G I -- PYE F PEEVL D EAAKI P EEVPE E EIKG RKDLR DLPFV TI 257
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 560 D PMT A R D L DDAV SI EKL G D NE Y EI GV H I S DVSH FLI E DNE LD NIVKE R S TS I YL ANE VI H MLP QS L CMR - CSL L P GQ D KF 638
Cdd:TIGR02063 258 D GED A K D F DDAV YV EKL K D GN Y KL GV A I A DVSH YVR E GSA LD KEALK R G TS V YL PDR VI P MLP ER L SNG i CSL N P NE D RL 337
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 639 AF S VFWRMNG KG VM lq KK P EF CRT VINS CSQFA Y EHAQK II - DNPNERFT E NDFPTI L NG fnpddirnrvlw L HDIASSI 717
Cdd:TIGR02063 338 TL S CEMEIDK KG RV -- KK Y EF YEA VINS HARLT Y NQVND II e GKDALDKK E PPLKEM L KN ------------ L FELYKIL 403
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 718 RK T R LDN GA LTINNAKLRFL LD P i T G E P LSFEVEKQRE A NR LIEEFM LL AN QA VA RFIHDS - F P di AVL R N H PP P LIKS L 796
Cdd:TIGR02063 404 RK K R KKR GA IDFDSKEAKII LD E - N G K P IDIVPRERGD A HK LIEEFM IA AN ET VA EHLEKA k L P -- FIY R V H ER P SEEK L 480
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 797 KA LRE K L LA LG FE L DYSS S KAL Q ESMVR -- L CNEAPN P VAM na CLSQL L MKP M AR A T Y fcsegks E P ADLW H YA L SIPI Y 874
Cdd:TIGR02063 481 QN LRE F L KT LG IT L KGGT S DKP Q PKDFQ kl L EKVKGR P EEE -- LINTV L LRS M QQ A K Y ------- S P ENIG H FG L ALEY Y 551
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 19922976 875 THFTSPIRRYPD IL VHRL LAA AL --- KYC T PP K RT --- PDD L HTLTKLANERKYN A KK A GE D SGNLYFKR Y VHN K Q G 945
Cdd:TIGR02063 552 THFTSPIRRYPD LI VHRL IKK AL fgg ENT T TE K ER eyl EAK L EEIAEHSSKTERR A DE A ER D VNDWKKAE Y MSE K I G 628
PRK05054
PRK05054 exoribonuclease II; Provisional
548-973
8.63e-38
exoribonuclease II; Provisional
Pssm-ID: 179920 [Multi-domain]
Cd Length: 644
Bit Score: 151.18
E-value: 8.63e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 548 R K DL RKMCIF TID PMTAR D L DDA VSI EKL G D NEYEIG V H I S D VSHFLI E DNE LD NIVKE R STSI YL ANEV I H MLP QS L C - 626
Cdd:PRK05054 190 R E DL TALDFV TID SASTE D M DDA LYV EKL P D GGLQLT V A I A D PTAYIA E GSK LD KAARQ R AFTN YL PGFN I P MLP RE L S d 269
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 627 MR CSL L P GQDKF A FSVFWRMNGK G V m LQKKPE F CRTV I N S CSQF AY EHAQKIID N PNERFT E N dfptilngfnp DD I RNR 706
Cdd:PRK05054 270 DL CSL R P NERRP A LACRVTIDAD G T - IEDDIR F FAAW I E S KAKL AY DNVSDWLE N GGDWQP E S ----------- EA I AEQ 337
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 707 VLW LH DIASSIRKT R LDNGALTINNAKL RF L L DP i T GE P L SFEV E KQ R E ANR LI EE F M LL AN QAV AR FIH D SF ------- 779
Cdd:PRK05054 338 IRL LH QFCLARSEW R KQHALVFKDRPDY RF E L GE - K GE V L DIVA E PR R I ANR IV EE S M IA AN ICA AR VLR D KL gfgiynv 416
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 780 ----- P D ----- I A V L RN H ppplik S L KALR E K LL A L - GF ----- ELD YSSSKA L q E S MV R lcneapnpvamnaclsqll 843
Cdd:PRK05054 417 hsgfd P A naeqa V A L L KE H ------ G L HFDA E E LL T L e GF cklrr ELD AQPTGY L - D S RI R ------------------- 470
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 844 mkpma R ATY F c S E GKS EP AD lw H YA L SIPI Y THF TSPIR R Y P D ILV HRLL A A AL K YC T PPK rt P D D l HTLTK LA NE R KY N 923
Cdd:PRK05054 471 ----- R FQS F - A E IST EP GP -- H FG L GLEA Y ATW TSPIR K Y G D MIN HRLL K A VI K GE T AER -- P Q D - EITVQ LA ER R RL N 539
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 19922976 924 a KK A GE D S G N - LY F k RY VHN K Q G IYM R -- A VV I E I FQHM M N V VT LE S G H V IS I 973
Cdd:PRK05054 540 - RM A ER D V G D w LY A - RY LKD K A G TDT R fa A EI I D I SRGG M R V RL LE N G A V AF I 590
OB_Dis3
pfam17849 Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 ...
442-518
8.27e-10
Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 protein. This domain along with CSD1 binds to RNA.
Pssm-ID: 436091 [Multi-domain]
Cd Length: 77
Bit Score: 56.08
E-value: 8.27e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19922976 442 FYK F R P Y D L R V P MVYV P KDACAAHIGNKQQ i D VS G L L YLAH I LETDC N - GHCIAELIQPV G RV G NLDD E LK AIL FH NG 518
Cdd:pfam17849 1 YVL F V P R D K R I P RIRI P TKSAPEEFLENPE - D LE G K L FVVK I DDWPE N s RYPLGHIVKVL G EI G DIET E TE AIL LE NG 77
Name
Accession
Description
Interval
E-value
RNB
pfam00773 RNB domain; This domain is the catalytic domain of ribonuclease II.
548-897
1.47e-97
RNB domain; This domain is the catalytic domain of ribonuclease II.
Pssm-ID: 459934 [Multi-domain]
Cd Length: 314
Bit Score: 310.76
E-value: 1.47e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 548 RKDLR KMCIF TIDP MT A R DLDDA V S I EKL GDNE Y EI GVHI S DVSH FLIEDNE LD NIVKE R S TS I YL ANE VI H MLP QS L CM 627
Cdd:pfam00773 1 RKDLR DLPFI TIDP AD A K DLDDA I S V EKL PNGG Y RL GVHI A DVSH YVPPGSP LD REARK R G TS V YL PDR VI P MLP EK L SN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 628 R - CSL L PG Q D KF A F SV FWRMNGK G VM lq KKP E FCRT VI N S CSQFA YE HAQKIIDNPNE rftendfptiln GFNPD D IRNR 706
Cdd:pfam00773 81 D l CSL N PG E D RL A L SV EITIDAD G EV -- TSY E IYPS VI R S KARLT YE EVDDLLEGKDA ------------ EKDKP D LAED 146
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 707 VLW L HDI A SSI R KT RL DN GAL TINNAKLRFL LD P it GEPLSFEVEKQRE A NR LIEEFMLLAN Q AVAR FIHD s FPDI A VL R 786
Cdd:pfam00773 147 LRL L YEL A KIL R AK RL QR GAL DLDTPENKLI LD E -- EGVIDILIQERTD A HS LIEEFMLLAN E AVAR HLQE - LGIP A LY R 223
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 787 N HP P P LIKS L KA L REK L LA L GFELDY S S S KALQESMV RL cneapnpvamnac LS Q LL MKP M A RA T Y F csegkse P AD L W H 866
Cdd:pfam00773 224 V HP E P DLEK L NS L IKL L QL L PDDKGL S K S LEKIKDDE RL ------------- LS I LL LRT M P RA E Y S ------- P EP L G H 283
330 340 350
....*....|....*....|....*....|.
gi 19922976 867 YA L SIP IYTHFTSPIRRYPD IL VHR L L A A A L 897
Cdd:pfam00773 284 FG L GLD IYTHFTSPIRRYPD LI VHR Q L K A L L 314
VacB
COG0557 Exoribonuclease R [Transcription];
408-917
1.11e-94
Exoribonuclease R [Transcription];
Pssm-ID: 440323 [Multi-domain]
Cd Length: 711
Bit Score: 316.28
E-value: 1.11e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 408 P KAF V IA I TK R T e LRQI VG TISFTNP tklcddql F YKFR P Y D L R VPM - VYV P K D ACA - A HI G NK qqid V sglly LAH I LE 485
Cdd:COG0557 122 P EGR V VE I LE R A - NTRV VG RFEKEKG -------- F GFVV P D D K R LLQ d IFI P P D DLN g A KD G DL ---- V ----- VVE I TR 183
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 486 TDCNGH ciaeli Q P V GRV ---- G NLD D --- E LKAILFHN GL RDI kp F EQRFIDIYSQP P PPISQE DL RQ R K DLR KMCIF T 558
Cdd:COG0557 184 YPERRG ------ P P E GRV vevl G SPG D pga E ILIAIRKH GL PHE -- F PEEVLAEAEAL P DEVPEA DL KG R R DLR DLPLV T 255
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 559 ID PMT A R D L DDAVS I EKL GDNEYEI GVHI S DVSH FLIEDNE LD NIVKE R S TS I YL ANE VI H MLP QS L C - MR CSL L PG Q D K 637
Cdd:COG0557 256 ID GED A K D F DDAVS A EKL DNGGWRL GVHI A DVSH YVRPGSA LD REARK R G TS V YL PDR VI P MLP ER L S n GL CSL N PG E D R 335
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 638 F A F S VFWRMNG KG VM lq KKP EF C R T VI N S CSQFA YE HA Q K I I D NPN E RFT E ND fptilngfnp D D IRNRVLW L HDI A SSI 717
Cdd:COG0557 336 L A M S CEMEIDA KG EV -- VSY EF Y R S VI R S DARLT YE EV Q A I L D GKD E ELR E EY ---------- A D LVPMLEE L YEL A KIL 403
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 718 RK T R LDN GA LTINNAKLRFL LD P i T G E P LSFEVEKQRE A NR LIEEFMLLAN Q AVA R F IHDS fp DIAV L - R N H PP P LIKS L 796
Cdd:COG0557 404 RK A R EKR GA IDFDLPETKII LD E - E G K P EDIVPRERND A HK LIEEFMLLAN E AVA E F LEKL -- KLPF L y R V H EE P DPEK L 480
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 797 K ALRE K L LA LG FE L --- D YSSS K A LQ esmv R L CNEAPNPVAMNA c L SQ LL MKP M AR A T Y fcsegks E P ADLW H YA L SIPI 873
Cdd:COG0557 481 E ALRE F L AN LG LK L kgg D EPTP K D LQ ---- K L LEQVKGRPEEEL - L NT LL LRS M KQ A V Y ------- S P ENIG H FG L ALEA 548
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 19922976 874 YTHFTSPIRRYPD I LVHR L L A A A L KYCTP P KRTPDDLHT L TKL A 917
Cdd:COG0557 549 YTHFTSPIRRYPD L LVHR A L K A Y L EGKRS P GLQEYLEEE L EEI A 592
RNB
smart00955 This domain is the catalytic domain of ribonuclease II;
548-898
1.91e-92
This domain is the catalytic domain of ribonuclease II;
Pssm-ID: 214935 [Multi-domain]
Cd Length: 286
Bit Score: 296.10
E-value: 1.91e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 548 R K DLR KMCI FTIDP MT A R D L DDAVS I EKL GDNE Y EI GVHI S DVSH FLIEDNE LD NIVKE R S TS I YL ANE VI H MLP QS L CM 627
Cdd:smart00955 1 R V DLR DLPL FTIDP ED A K D I DDAVS V EKL DNGG Y RL GVHI A DVSH YVKPGSA LD REARK R G TS V YL PDR VI P MLP EE L SN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 628 - R CSL L PG Q D KF A F SV FWRMNGK G VMLQKK p EF C R T VI N S CSQFA YE HAQK I ID npnerftendfptilngfnpddirnr 706
Cdd:smart00955 81 g L CSL N PG E D RL A L SV EMTLDAD G GEILDY - EF Y R S VI R S KARLT YE EVDA I LE -------------------------- 133
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 707 vlwlhdiassirktrldngaltinnakl RFL LD P i T G EPLSFEVEKQRE A NR L I EEFM L LAN Q AVARF IHDSFPD i AVL R 786
Cdd:smart00955 134 ---------------------------- KIV LD E - E G KIEDIVPRERND A HS L V EEFM I LAN E AVARF LAKNGIP - GLY R 183
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 787 N H PP P - LI K SLKA L R E K L LA LG FE L - DYSSS KAL QESMVRLCNEAPNPV amnac L SQ LL MKP M AR A T Y FCSEGK sepadl 864
Cdd:smart00955 184 V H EG P d PE K LAEL L K E F L AL LG LL L l GGDGP KAL AKLLEKIRDSPEERL ----- L EL LL LRS M PH A E Y SVDNSG ------ 252
330 340 350
....*....|....*....|....*....|....
gi 19922976 865 w H YA L SIPI YTHFTSPIRRYPD IL VHR L L A AAL K 898
Cdd:smart00955 253 - H FG L ALDA YTHFTSPIRRYPD LI VHR Q L K AAL R 285
RNase_R
TIGR02063 ribonuclease R; This family consists of an exoribonuclease, ribonuclease R, also called VacB. ...
408-945
3.68e-82
ribonuclease R; This family consists of an exoribonuclease, ribonuclease R, also called VacB. It is one of the eight exoribonucleases reported in E. coli and is broadly distributed throughout the bacteria. In E. coli, double mutants of this protein and polynucleotide phosphorylase are not viable. Scoring between trusted and noise cutoffs to the model are shorter, divergent forms from the Chlamydiae, and divergent forms from the Campylobacterales (including Helicobacter pylori) and Leptospira interrogans. [Transcription, Degradation of RNA]
Pssm-ID: 273947 [Multi-domain]
Cd Length: 709
Bit Score: 281.85
E-value: 3.68e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 408 PK A F VI A I TK R T e LR QIVGT ISFT N PTKLC --- D DQLFYKF rpydlrvpmv YV P KDACA - A HI G N K qqidvsgll Y L AH I 483
Cdd:TIGR02063 123 FE A R VI K I LE R A - ND QIVGT FYIE N GIGFV ipd D KRIYLDI ---------- FI P PEQIL g A EE G D K --------- V L VE I 182
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 484 LE - T D C N GHC I AELIQ pvg RV G NL DD --- ELKA I LFHN G L rd IKP F EQRFI D IYSQP P PPISQ E DLRQ RKDLR KMCIF TI 559
Cdd:TIGR02063 183 TK y P D R N RPA I GKVVE --- IL G HA DD pgi DILI I IRKH G I -- PYE F PEEVL D EAAKI P EEVPE E EIKG RKDLR DLPFV TI 257
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 560 D PMT A R D L DDAV SI EKL G D NE Y EI GV H I S DVSH FLI E DNE LD NIVKE R S TS I YL ANE VI H MLP QS L CMR - CSL L P GQ D KF 638
Cdd:TIGR02063 258 D GED A K D F DDAV YV EKL K D GN Y KL GV A I A DVSH YVR E GSA LD KEALK R G TS V YL PDR VI P MLP ER L SNG i CSL N P NE D RL 337
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 639 AF S VFWRMNG KG VM lq KK P EF CRT VINS CSQFA Y EHAQK II - DNPNERFT E NDFPTI L NG fnpddirnrvlw L HDIASSI 717
Cdd:TIGR02063 338 TL S CEMEIDK KG RV -- KK Y EF YEA VINS HARLT Y NQVND II e GKDALDKK E PPLKEM L KN ------------ L FELYKIL 403
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 718 RK T R LDN GA LTINNAKLRFL LD P i T G E P LSFEVEKQRE A NR LIEEFM LL AN QA VA RFIHDS - F P di AVL R N H PP P LIKS L 796
Cdd:TIGR02063 404 RK K R KKR GA IDFDSKEAKII LD E - N G K P IDIVPRERGD A HK LIEEFM IA AN ET VA EHLEKA k L P -- FIY R V H ER P SEEK L 480
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 797 KA LRE K L LA LG FE L DYSS S KAL Q ESMVR -- L CNEAPN P VAM na CLSQL L MKP M AR A T Y fcsegks E P ADLW H YA L SIPI Y 874
Cdd:TIGR02063 481 QN LRE F L KT LG IT L KGGT S DKP Q PKDFQ kl L EKVKGR P EEE -- LINTV L LRS M QQ A K Y ------- S P ENIG H FG L ALEY Y 551
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 19922976 875 THFTSPIRRYPD IL VHRL LAA AL --- KYC T PP K RT --- PDD L HTLTKLANERKYN A KK A GE D SGNLYFKR Y VHN K Q G 945
Cdd:TIGR02063 552 THFTSPIRRYPD LI VHRL IKK AL fgg ENT T TE K ER eyl EAK L EEIAEHSSKTERR A DE A ER D VNDWKKAE Y MSE K I G 628
3_prime_RNase
TIGR00358 VacB and RNase II family 3'-5' exoribonucleases; This model is defined to identify a pair of ...
410-955
2.35e-59
VacB and RNase II family 3'-5' exoribonucleases; This model is defined to identify a pair of paralogous 3-prime exoribonucleases in E. coli, plus the set of proteins apparently orthologous to one or the other in other eubacteria. VacB was characterized originally as required for the expression of virulence genes, but is now recognized as the exoribonuclease RNase R (Rnr). Its paralog in E. coli and H. influenzae is designated exoribonuclease II (Rnb). Both are involved in the degradation of mRNA, and consequently have strong pleiotropic effects that may be difficult to disentangle. Both these proteins share domain-level similarity (RNB, S1) with a considerable number of other proteins, and full-length similarity scoring below the trusted cutoff to proteins associated with various phenotypes but uncertain biochemistry; it may be that these latter proteins are also 3-prime exoribonucleases. [Transcription, Degradation of RNA]
Pssm-ID: 273033 [Multi-domain]
Cd Length: 654
Bit Score: 216.12
E-value: 2.35e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 410 A F V IA I TKRT e L RQI VG TISFT N PTK -- LC DD QLF Y K frpy D LR VP MVY V PKDA caahignkqqid VS G LLYLAHIL E TD 487
Cdd:TIGR00358 72 A E V ER I LEPA - L TRF VG KFLGE N DFG fv VP DD PRI Y L ---- D II VP KAS V KNEL ------------ AE G DKVVVELT E YP 134
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 488 C - NGHCIA E LI Q pvg RV GN L DD E L --- KAI L FHNGL rdik PFE qr F I D IYS Q P ---- PPPISQEDLRQ R K DL RKMCIF TI 559
Cdd:TIGR00358 135 L r RNLFYG E IT Q --- IL GN N DD P L ipw WVT L ARHEI ---- PFE -- F P D GVE Q Q aakl QFDVDEQAKKY R E DL TDLAFV TI 205
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 560 D PMT A R DLDDAV SIE KL G D NEYEIG V H I S DVS HFLI E DNE LD NIV K E R ST S I YL ANE VI H MLP QS L CMR - CSL L P GQ D KF 638
Cdd:TIGR00358 206 D GAD A K DLDDAV YVK KL P D GGWKLY V A I A DVS YYVA E NSP LD KEA K H R GF S V YL PGF VI P MLP EE L SNG l CSL N P NE D RL 285
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 639 AFSVFWRMNGK G VMLQK kp EF CRTV I N S CSQFA Y EHAQKIID N PN E RFT E nd FP T ILNGFN pddirnrvl W LH DIASSIR 718
Cdd:TIGR00358 286 VLVCEMTISAQ G RITDN -- EF YPAT I E S KARLT Y DKVNDWLE N DD E LQP E -- YE T LVEQLK --------- A LH QLSQALG 352
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 719 KT R LDN G ALTINNAKLR F LL D P i T G EPLSFEV E KQ R E A NRL IEE F M LL AN QAV ARF I H DS f PDIAVL R N HP P P LI K S L KA 798
Cdd:TIGR00358 353 EW R HKR G LIDFEHPETK F IV D E - E G RVIDIVA E VR R I A EKI IEE A M IV AN ICA ARF L H NH - KVPGIY R V HP G P SK K K L QS 430
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 799 L R E K L LA LG ----- FELDYSSSKALQESMVR lcn EAPN P VA mn AC L SQL L MKPMAR A T Y fcseg KS EP ad L W H YA L SIPI 873
Cdd:TIGR00358 431 L L E F L AE LG ltlpg GNAENVTTLDGACWLRE --- VKDR P EY -- EI L VTR L LRSLSQ A E Y ----- SP EP -- L G H FG L GLEH 498
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 874 Y T HFTSPIRRYPD ILV HRL LA A A L KYCTPPKRTPDDLHT L TKL A NERKYNAKK A GE --- D SGNLYFK RY VHN K Q G IYMRA 950
Cdd:TIGR00358 499 Y A HFTSPIRRYPD LTN HRL IK A V L AKEQTDTERYQPQDE L LQI A EHCSDTERR A RD aer D VADWLKC RY LLD K V G TEFSG 578
....*
gi 19922976 951 VVIEI 955
Cdd:TIGR00358 579 EISSV 583
PRK05054
PRK05054 exoribonuclease II; Provisional
548-973
8.63e-38
exoribonuclease II; Provisional
Pssm-ID: 179920 [Multi-domain]
Cd Length: 644
Bit Score: 151.18
E-value: 8.63e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 548 R K DL RKMCIF TID PMTAR D L DDA VSI EKL G D NEYEIG V H I S D VSHFLI E DNE LD NIVKE R STSI YL ANEV I H MLP QS L C - 626
Cdd:PRK05054 190 R E DL TALDFV TID SASTE D M DDA LYV EKL P D GGLQLT V A I A D PTAYIA E GSK LD KAARQ R AFTN YL PGFN I P MLP RE L S d 269
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 627 MR CSL L P GQDKF A FSVFWRMNGK G V m LQKKPE F CRTV I N S CSQF AY EHAQKIID N PNERFT E N dfptilngfnp DD I RNR 706
Cdd:PRK05054 270 DL CSL R P NERRP A LACRVTIDAD G T - IEDDIR F FAAW I E S KAKL AY DNVSDWLE N GGDWQP E S ----------- EA I AEQ 337
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 707 VLW LH DIASSIRKT R LDNGALTINNAKL RF L L DP i T GE P L SFEV E KQ R E ANR LI EE F M LL AN QAV AR FIH D SF ------- 779
Cdd:PRK05054 338 IRL LH QFCLARSEW R KQHALVFKDRPDY RF E L GE - K GE V L DIVA E PR R I ANR IV EE S M IA AN ICA AR VLR D KL gfgiynv 416
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 780 ----- P D ----- I A V L RN H ppplik S L KALR E K LL A L - GF ----- ELD YSSSKA L q E S MV R lcneapnpvamnaclsqll 843
Cdd:PRK05054 417 hsgfd P A naeqa V A L L KE H ------ G L HFDA E E LL T L e GF cklrr ELD AQPTGY L - D S RI R ------------------- 470
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 844 mkpma R ATY F c S E GKS EP AD lw H YA L SIPI Y THF TSPIR R Y P D ILV HRLL A A AL K YC T PPK rt P D D l HTLTK LA NE R KY N 923
Cdd:PRK05054 471 ----- R FQS F - A E IST EP GP -- H FG L GLEA Y ATW TSPIR K Y G D MIN HRLL K A VI K GE T AER -- P Q D - EITVQ LA ER R RL N 539
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 19922976 924 a KK A GE D S G N - LY F k RY VHN K Q G IYM R -- A VV I E I FQHM M N V VT LE S G H V IS I 973
Cdd:PRK05054 540 - RM A ER D V G D w LY A - RY LKD K A G TDT R fa A EI I D I SRGG M R V RL LE N G A V AF I 590
Rnb
COG4776 Exoribonuclease II [Transcription];
542-973
1.02e-36
Exoribonuclease II [Transcription];
Pssm-ID: 443808 [Multi-domain]
Cd Length: 644
Bit Score: 148.08
E-value: 1.02e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 542 QEDLRQ R K DL RKMCIF TID PMTAR D L DDA VS IEKL GDNEYEIG V H I S D VSHFLI E DN ELD NIVKE R STSI YL ANEV I H ML 621
Cdd:COG4776 184 LDEGLE R E DL TALPFV TID SESTE D M DDA LY IEKL ENGGWKLT V A I A D PTAYIP E GS ELD KEARQ R AFTN YL PGFN I P ML 263
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 622 P QS L C - MR CSL LPGQDKF A F -- S V FWRMN G K gvm LQKKP EF CRTV I N S CSQF AY EHAQKIIDNPN E RFT EN D fptilngf 698
Cdd:COG4776 264 P RE L S d DL CSL KENEKRP A L vc R V TIDAD G S --- IGDDI EF FAAW I R S KAKL AY DNVSDWLEGKG E WQP EN E -------- 332
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 699 npd D I RNRVLW LH DI A SSIRKT R LDNGALTINNAKL RF L LD P i T G EP L SFEV E KQ R E ANR LI EE F M LL AN QAV AR F ---- 774
Cdd:COG4776 333 --- E I AEQIRL LH QF A LARSQW R QQHALVFKDRPDY RF E LD E - K G NV L DIHA E PR R I ANR IV EE A M IA AN ICA AR V lreh 408
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 775 ------- I H DS F PD ------ IAV L RN H PPPLIK slkalr E K LL A L - GF ----- ELD YSSSKA L q E S MV R LCN eapnpvam 835
Cdd:COG4776 409 lgfgifn V H SG F DP ekleqa VEL L AE H GIEFDP ------ E Q LL T L e GF calrr ELD AQPTSY L - D S RL R RFQ -------- 473
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 836 naclsqllmkpmara T Y fc S E GKS EP AD lw H YA L SIPI Y THF TSPIR R Y P D ILV HRL LA A ALKY c T P PKRTPDD L ht LTK 915
Cdd:COG4776 474 --------------- T F -- A E IST EP GP -- H FG L GLDA Y ATW TSPIR K Y G D MVN HRL IK A VILG - Q P AEKPDEE L -- TER 531
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 916 LA NE R KY N a KK A GE D SGNLYFK RY VHN K -- Q G IYMR A VV I E I FQHMMN V VT LE S G H V IS I 973
Cdd:COG4776 532 LA ER R RL N - RM A ER D VADWLYA RY LKP K vg S G QVFT A EI I D I NRGGLR V RL LE N G A V AF I 590
PRK11642
PRK11642 ribonuclease R;
548-899
3.97e-33
ribonuclease R;
Pssm-ID: 236944 [Multi-domain]
Cd Length: 813
Bit Score: 137.95
E-value: 3.97e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 548 R K DLR KMCIF TID PMT ARD L DDAV SI EK LGDNEYEIG V H I S DVS HFLIEDNE LD NIVKE R S TS I Y LANE V IH MLP QS L CM 627
Cdd:PRK11642 260 R V DLR DLPLV TID GED ARD F DDAV YC EK KRGGGWRLW V A I A DVS YYVRPPTP LD REARN R G TS V Y FPSQ V VP MLP EV L SN 339
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 628 - R CSL L P GQ D KFAFSVFWRMNG KG VMLQK K pe F CRT V IN S CSQFA Y EHAQK I IDN p NERFT E NDF P TI lngfnpddir NR 706
Cdd:PRK11642 340 g L CSL N P QV D RLCMVCEMTISS KG RLTGY K -- F YEA V MS S HARLT Y TKVWH I LQG - DQDLR E QYA P LV ---------- KH 406
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 707 VLW LH DIASSIR K T R LDN G ALTINNAKLR F L ldpitgepls F EV E KQR E --------- A NR LIEE F M L LAN QAV ARF IHD 777
Cdd:PRK11642 407 LEE LH NLYKVLD K A R EER G GISFESEEAK F I ---------- F NA E RRI E rieqtqrnd A HK LIEE C M I LAN ISA ARF VEK 476
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922976 778 S f PDI A VL R N H PP P LIKSLKAL R EK L LA LG F EL DYSSSKALQESMVR L CNE A PN P V A mn AC L SQL L MKP M AR A T Y fcseg 857
Cdd:PRK11642 477 A - KEP A LF R I H DK P STEAITSF R SV L AE LG L EL PGGNKPEPRDYAEL L ESV A DR P D A -- EM L QTM L LRS M KQ A I Y ----- 548
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 19922976 858 ks E P ADLW H YA L SIPI Y T HFTSPIRRYPD ILV HR llaa A L KY 899
Cdd:PRK11642 549 -- D P ENRG H FG L ALQS Y A HFTSPIRRYPD LSL HR ---- A I KY 584
OB_Dis3
pfam17849 Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 ...
442-518
8.27e-10
Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 protein. This domain along with CSD1 binds to RNA.
Pssm-ID: 436091 [Multi-domain]
Cd Length: 77
Bit Score: 56.08
E-value: 8.27e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19922976 442 FYK F R P Y D L R V P MVYV P KDACAAHIGNKQQ i D VS G L L YLAH I LETDC N - GHCIAELIQPV G RV G NLDD E LK AIL FH NG 518
Cdd:pfam17849 1 YVL F V P R D K R I P RIRI P TKSAPEEFLENPE - D LE G K L FVVK I DDWPE N s RYPLGHIVKVL G EI G DIET E TE AIL LE NG 77
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
