|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
346-718 |
6.98e-25 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 108.87 E-value: 6.98e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 346 LLDLAENNITKIEKNSFKDIYQAIINVSHNALELIETAAFENCVNITVLDLSHNRlanfsrrSFDETTFATYFQLSYNNL 425
Cdd:COG4886 53 LSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQL 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 426 TNLAQIpIQNMTGLKVLNASYNSITEIPKNcFPKLYELHTIDVSHNNISSIFNGVFQtLFSLRSIDLSHNSMREIkSSTF 505
Cdd:COG4886 126 TDLPEE-LANLTNLKELDLSNNQLTDLPEP-LGNLTNLKSLDLSNNQLTDLPEELGN-LTNLKELDLSNNQITDL-PEPL 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 506 GTLPTLLEMDLSHNELvSVVRGSLAKLTSLRQLYLNNNQLEKLFQLP--ISLNELYFSHNRLTNIPSGTWpvMNSLIYLD 583
Cdd:COG4886 202 GNLTNLEELDLSGNQL-TDLPEPLANLTNLETLDLSNNQLTDLPELGnlTNLEELDLSNNQLTDLPPLAN--LTNLKTLD 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 584 LSHNQLGDTLNGESFTGLLVVQRLKLQNNGISQPPKDAVAVMSTLQYLHLENNNITTLERSAFGKLPVLFELNLYGNQVK 663
Cdd:COG4886 279 LSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNL 358
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 161077058 664 DISKRAFEGLLQLLTLNLSSNGIQTLQNDIFVGLPSLRNLDLSFNSLTKLDNKTN 718
Cdd:COG4886 359 LSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNT 413
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
387-888 |
1.10e-24 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 111.48 E-value: 1.10e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 387 NCVNITVLDLSHNRLANFSRRSFDETTFATYFQLSYNNLTnlAQIP---IQNMTGLKVLNASYNSIT-EIPKNCFPKLYe 462
Cdd:PLN00113 67 NSSRVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLS--GPIPddiFTTSSSLRYLNLSNNNFTgSIPRGSIPNLE- 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 463 lhTIDVSHNNISSIFNGVFQTLFSLRSIDLSHNSMREIKSSTFGTLPTLLEMDLSHNELVSVVRGSLAKLTSLRQLYLNN 542
Cdd:PLN00113 144 --TLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGY 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 543 NQLE-----KLFQLpISLNELYFSHNRLTN-IPSGTWPVMNsLIYLDLSHNQLGDTLNGESFtGLLVVQRLKLQNNGISQ 616
Cdd:PLN00113 222 NNLSgeipyEIGGL-TSLNHLDLVYNNLTGpIPSSLGNLKN-LQYLFLYQNKLSGPIPPSIF-SLQKLISLDLSDNSLSG 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 617 PPKDAVAVMSTLQYLHLENNNITTLERSAFGKLPVLFELNLYGNQV-----KDISKRafeglLQLLTLNLSSNGIQTLQN 691
Cdd:PLN00113 299 EIPELVIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFsgeipKNLGKH-----NNLTVLDLSTNNLTGEIP 373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 692 DIFVGLPSLRNLDLSFNSLtklDNKTNGVLDDLLSLETLDLSHNRISFVTKKTFPSHQYIPY-NLRNLNLSYNL------ 764
Cdd:PLN00113 374 EGLCSSGNLFKLILFSNSL---EGEIPKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFlDISNNNLQGRInsrkwd 450
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 765 MPILTY------------DITFGTKKLVRLDVSHNQINDLRRGVISNFTSLQSLDMSYNELSNLKSEEhiFDLPQNLSWL 832
Cdd:PLN00113 451 MPSLQMlslarnkffgglPDSFGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDE--LSSCKKLVSL 528
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 161077058 833 DLSHNKIY-HLPfANLVKVKSLKYVDLTNNSLE-DVPASIvGSMRNGSQVLLAGNPLH 888
Cdd:PLN00113 529 DLSHNQLSgQIP-ASFSEMPVLSQLDLSQNQLSgEIPKNL-GNVESLVQVNISHNHLH 584
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
486-738 |
1.68e-12 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 69.69 E-value: 1.68e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 486 SLRSIDLSHNSMREIKSST------FGTLPTLLEMDLSHNELVSVVRGSLAKLT---SLRQLYLNNNQLEK--------- 547
Cdd:cd00116 52 SLKELCLSLNETGRIPRGLqsllqgLTKGCGLQELDLSDNALGPDGCGVLESLLrssSLQELKLNNNGLGDrglrllakg 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 548 LFQLPISLNELYFSHNRLTNIP----SGTWPVMNSLIYLDLSHNQLGDTLngesftgllvVQRLKLqnngisqppkdAVA 623
Cdd:cd00116 132 LKDLPPALEKLVLGRNRLEGAScealAKALRANRDLKELNLANNGIGDAG----------IRALAE-----------GLK 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 624 VMSTLQYLHLENNNITTLERSAFG----KLPVLFELNLYGNQVkdiskrafegllqlltlnlSSNGIQTLQNDIFVGLPS 699
Cdd:cd00116 191 ANCNLEVLDLNNNGLTDEGASALAetlaSLKSLEVLNLGDNNL-------------------TDAGAAALASALLSPNIS 251
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 161077058 700 LRNLDLSFNSLTKLDNKT-NGVLDDLLSLETLDLSHNRIS 738
Cdd:cd00116 252 LLTLSLSCNDITDDGAKDlAEVLAEKESLLELDLRGNKFG 291
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
631-849 |
1.48e-11 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 65.19 E-value: 1.48e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 631 LHLENNNITTLER-SAFGKLPVLFelnLYGNQvkdiskrafegllqlltlnlssngIQTLQNdiFVGLPSLRNLDLSFNS 709
Cdd:cd21340 7 LYLNDKNITKIDNlSLCKNLKVLY---LYDNK------------------------ITKIEN--LEFLTNLTHLYLQNNQ 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 710 LTKLDNktngvLDDLLSLETLDLSHNRISFVtkktfpSHQYIPYNLRNLNLSYNLMPI---LTYD---ITFGTKKLVRLD 783
Cdd:cd21340 58 IEKIEN-----LENLVNLKKLYLGGNRISVV------EGLENLTNLEELHIENQRLPPgekLTFDprsLAALSNSLRVLN 126
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 161077058 784 VSHNQINDLRrgVISNFTSLQSLDMSYNELSNLKS-EEHIFDLPQnLSWLDLSHNkiyhlPFANLVK 849
Cdd:cd21340 127 ISGNNIDSLE--PLAPLRNLEQLDASNNQISDLEElLDLLSSWPS-LRELDLTGN-----PVCKKPK 185
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
486-545 |
1.71e-10 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 57.53 E-value: 1.71e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 486 SLRSIDLSHNSMREIKSSTFGTLPTLLEMDLSHNELVSVVRGSLAKLTSLRQLYLNNNQL 545
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
606-887 |
4.38e-09 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 60.48 E-value: 4.38e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 606 RLKLQNNGISQPPKDAVAVMSTLQylhLENNNITTLERsafgklpvlfelNLYGNqVKDISKRAfegLLQLLTLNLSSNG 685
Cdd:PRK15370 182 ELRLKILGLTTIPACIPEQITTLI---LDNNELKSLPE------------NLQGN-IKTLYANS---NQLTSIPATLPDT 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 686 IQTLQNDI--FVGLP-----SLRNLDLSFNSLTKL-DNKTNGvlddllsLETLDLSHNRIsfvtkKTFPSHqyIPYNLRN 757
Cdd:PRK15370 243 IQEMELSInrITELPerlpsALQSLDLFHNKISCLpENLPEE-------LRYLSVYDNSI-----RTLPAH--LPSGITH 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 758 LNLSYNLMPILTYDITFGTKKLVRLDvshNQINDLRRGVISnftSLQSLDMSYNELSNLKSEehifdLPQNLSWLDLSHN 837
Cdd:PRK15370 309 LNVQSNSLTALPETLPPGLKTLEAGE---NALTSLPASLPP---ELQVLDVSKNQITVLPET-----LPPTITTLDVSRN 377
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 161077058 838 KIYHLPfANLvkVKSLKYVDLTNNSLEDVPASIVGSMRNGSQ---VLLAGNPL 887
Cdd:PRK15370 378 ALTNLP-ENL--PAALQIMQASRNNLVRLPESLPHFRGEGPQptrIIVEYNPF 427
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
198-258 |
7.12e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 52.91 E-value: 7.12e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 161077058 198 RKLKTLDLHGNQLENLKRNQFKNLRELEVLDISHNQIKKLEAQHIADLTKLGWCNVSHNAL 258
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
191-359 |
2.62e-08 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 55.56 E-value: 2.62e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 191 IETFQPLRKLKTLDLHGNQLENLKrnQFKNLRELEVLDISHNQIKKLE-AQHIADLTKLgwcNVSHNALSELSrGtFARN 269
Cdd:cd21340 17 IDNLSLCKNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKIEnLENLVNLKKL---YLGGNRISVVE-G-LENL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 270 SVLKVLHLSHNQIAR-----LDANSFRGM-RFLRRLFLSDNVLTDIgrGTFGSIARIGTIDLARNRLKKIE--FQMFTQM 341
Cdd:cd21340 90 TNLEELHIENQRLPPgekltFDPRSLAALsNSLRVLNISGNNIDSL--EPLAPLRNLEQLDASNNQISDLEelLDLLSSW 167
|
170
....*....|....*...
gi 161077058 342 NYVELLDLAENNITKIEK 359
Cdd:cd21340 168 PSLRELDLTGNPVCKKPK 185
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
245-306 |
3.18e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 50.99 E-value: 3.18e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 161077058 245 LTKLgwcNVSHNALSELSRGTFARNSVLKVLHLSHNQIARLDANSFRGMRFLRRLFLSDNVL 306
Cdd:pfam13855 3 LRSL---DLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
778-839 |
2.05e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 48.67 E-value: 2.05e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 161077058 778 KLVRLDVSHNQINDLRRGVISNFTSLQSLDMSYNELSNLkSEEHIFDLPqNLSWLDLSHNKI 839
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTL-SPGAFSGLP-SLRYLDLSGNRL 61
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
191-361 |
5.08e-05 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 47.09 E-value: 5.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 191 IETFQPLRKLKTLDLHGNQL---------ENLKRNqfknlRELEVLDISHNQIkklEAQHIADLTKlgwcnvshnalsel 261
Cdd:COG5238 229 AEALKGNKSLTTLDLSNNQIgdegvialaEALKNN-----TTVETLYLSGNQI---GAEGAIALAK-------------- 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 262 srgTFARNSVLKVLHLSHNQI----ARLDANSFRGMRFLRRLFLSDNVLTDIG-RGTFGSI---ARIGTIDLARNRLKK- 332
Cdd:COG5238 287 ---ALQGNTTLTSLDLSVNRIgdegAIALAEGLQGNKTLHTLNLAYNGIGAQGaIALAKALqenTTLHSLDLSDNQIGDe 363
|
170 180 190
....*....|....*....|....*....|..
gi 161077058 333 --IEFQMFTQMN-YVELLDLAENNITKIEKNS 361
Cdd:COG5238 364 gaIALAKYLEGNtTLRELNLGKNNIGKQGAEA 395
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
197-259 |
4.80e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 40.95 E-value: 4.80e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 161077058 197 LRKLKTLDLHGNQLENLKRNQFKNLRELEVLDISHNQIKKLEAQHIADLTKLGWCNVSHNALS 259
Cdd:PLN03150 441 LRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLS 503
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
346-718 |
6.98e-25 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 108.87 E-value: 6.98e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 346 LLDLAENNITKIEKNSFKDIYQAIINVSHNALELIETAAFENCVNITVLDLSHNRlanfsrrSFDETTFATYFQLSYNNL 425
Cdd:COG4886 53 LSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQL 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 426 TNLAQIpIQNMTGLKVLNASYNSITEIPKNcFPKLYELHTIDVSHNNISSIFNGVFQtLFSLRSIDLSHNSMREIkSSTF 505
Cdd:COG4886 126 TDLPEE-LANLTNLKELDLSNNQLTDLPEP-LGNLTNLKSLDLSNNQLTDLPEELGN-LTNLKELDLSNNQITDL-PEPL 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 506 GTLPTLLEMDLSHNELvSVVRGSLAKLTSLRQLYLNNNQLEKLFQLP--ISLNELYFSHNRLTNIPSGTWpvMNSLIYLD 583
Cdd:COG4886 202 GNLTNLEELDLSGNQL-TDLPEPLANLTNLETLDLSNNQLTDLPELGnlTNLEELDLSNNQLTDLPPLAN--LTNLKTLD 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 584 LSHNQLGDTLNGESFTGLLVVQRLKLQNNGISQPPKDAVAVMSTLQYLHLENNNITTLERSAFGKLPVLFELNLYGNQVK 663
Cdd:COG4886 279 LSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNL 358
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 161077058 664 DISKRAFEGLLQLLTLNLSSNGIQTLQNDIFVGLPSLRNLDLSFNSLTKLDNKTN 718
Cdd:COG4886 359 LSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNT 413
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
387-888 |
1.10e-24 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 111.48 E-value: 1.10e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 387 NCVNITVLDLSHNRLANFSRRSFDETTFATYFQLSYNNLTnlAQIP---IQNMTGLKVLNASYNSIT-EIPKNCFPKLYe 462
Cdd:PLN00113 67 NSSRVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLS--GPIPddiFTTSSSLRYLNLSNNNFTgSIPRGSIPNLE- 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 463 lhTIDVSHNNISSIFNGVFQTLFSLRSIDLSHNSMREIKSSTFGTLPTLLEMDLSHNELVSVVRGSLAKLTSLRQLYLNN 542
Cdd:PLN00113 144 --TLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGY 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 543 NQLE-----KLFQLpISLNELYFSHNRLTN-IPSGTWPVMNsLIYLDLSHNQLGDTLNGESFtGLLVVQRLKLQNNGISQ 616
Cdd:PLN00113 222 NNLSgeipyEIGGL-TSLNHLDLVYNNLTGpIPSSLGNLKN-LQYLFLYQNKLSGPIPPSIF-SLQKLISLDLSDNSLSG 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 617 PPKDAVAVMSTLQYLHLENNNITTLERSAFGKLPVLFELNLYGNQV-----KDISKRafeglLQLLTLNLSSNGIQTLQN 691
Cdd:PLN00113 299 EIPELVIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFsgeipKNLGKH-----NNLTVLDLSTNNLTGEIP 373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 692 DIFVGLPSLRNLDLSFNSLtklDNKTNGVLDDLLSLETLDLSHNRISFVTKKTFPSHQYIPY-NLRNLNLSYNL------ 764
Cdd:PLN00113 374 EGLCSSGNLFKLILFSNSL---EGEIPKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFlDISNNNLQGRInsrkwd 450
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 765 MPILTY------------DITFGTKKLVRLDVSHNQINDLRRGVISNFTSLQSLDMSYNELSNLKSEEhiFDLPQNLSWL 832
Cdd:PLN00113 451 MPSLQMlslarnkffgglPDSFGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDE--LSSCKKLVSL 528
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 161077058 833 DLSHNKIY-HLPfANLVKVKSLKYVDLTNNSLE-DVPASIvGSMRNGSQVLLAGNPLH 888
Cdd:PLN00113 529 DLSHNQLSgQIP-ASFSEMPVLSQLDLSQNQLSgEIPKNL-GNVESLVQVNISHNHLH 584
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
411-835 |
3.34e-22 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 100.78 E-value: 3.34e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 411 ETTFATYFQLSYNNLTNLAQIPIQNMTGLKVLNASYNSITEIPKNCFPKLYELHTIDVSHNNISSIFNGVFQTLFSLRSI 490
Cdd:COG4886 22 TTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTEL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 491 DLSHNSmreikssTFGTLPTLLEMDLSHNELVSVVRgSLAKLTSLRQLYLNNNQL----EKLFQLPiSLNELYFSHNRLT 566
Cdd:COG4886 102 DLSGNE-------ELSNLTNLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLtdlpEPLGNLT-NLKSLDLSNNQLT 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 567 NIPSGTWPvMNSLIYLDLSHNQLGDTlnGESFTGLLVVQRLKLQNNGISQPPkDAVAVMSTLQYLHLENNNITTLErsAF 646
Cdd:COG4886 173 DLPEELGN-LTNLKELDLSNNQITDL--PEPLGNLTNLEELDLSGNQLTDLP-EPLANLTNLETLDLSNNQLTDLP--EL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 647 GKLPVLFELNLYGNQVKDISKRAfegllqlltlnlssngiqtlqndifvGLPSLRNLDLSFNSLTKLDNKTNGVLDDLLS 726
Cdd:COG4886 247 GNLTNLEELDLSNNQLTDLPPLA--------------------------NLTNLKTLDLSNNQLTDLKLKELELLLGLNS 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 727 LETLDLSHNRISFVTKKTFPSHQYIPYNLRNLNLSYNLMPILTYDITFGTKKLVRLDVSHNQINDLRRGVISNFTSLQSL 806
Cdd:COG4886 301 LLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLL 380
|
410 420
....*....|....*....|....*....
gi 161077058 807 DMSYNELSNLKSEEHIFDLPQNLSWLDLS 835
Cdd:COG4886 381 TLALLLLTLLLLLLTTTAGVLLLTLALLD 409
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
342-794 |
3.29e-21 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 97.70 E-value: 3.29e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 342 NYVELLDLAENNITKIEKNSFKDIYQAIINVSHNALELIETAAFENCVNITVLDLSHNRLANFSRRSFDETTFATYFQLS 421
Cdd:COG4886 1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 422 YNNLTNLAQIPIQNMTGLKVLNASYNSIteipkncFPKLYELHTIDVSHNNISSIFNGVFQtLFSLRSIDLSHNSMREIk 501
Cdd:COG4886 81 LLSLLLLGLTDLGDLTNLTELDLSGNEE-------LSNLTNLESLDLSGNQLTDLPEELAN-LTNLKELDLSNNQLTDL- 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 502 SSTFGTLPTLLEMDLSHNELvSVVRGSLAKLTSLRQLYLNNNQLEK----LFQLPiSLNELYFSHNRLTNIPSgTWPVMN 577
Cdd:COG4886 152 PEPLGNLTNLKSLDLSNNQL-TDLPEELGNLTNLKELDLSNNQITDlpepLGNLT-NLEELDLSGNQLTDLPE-PLANLT 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 578 SLIYLDLSHNQLGDTlngesftgllvvqrlklqnngisqppkDAVAVMSTLQYLHLENNNITTLerSAFGKLPVLFELNL 657
Cdd:COG4886 229 NLETLDLSNNQLTDL---------------------------PELGNLTNLEELDLSNNQLTDL--PPLANLTNLKTLDL 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 658 YGNQVKDISKRAFEGLLQLLTLNLSSNGIqtLQNDIFVGLPSLRNLDLSFNSLTKLDNKTNGVLDDLLSLETLDLSHNRI 737
Cdd:COG4886 280 SNNQLTDLKLKELELLLGLNSLLLLLLLL--NLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLN 357
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 161077058 738 SFVTKKTFPSHQYIPYNLRNLNLSYNLMPILTYDITFGTKKLVRLDVSHNQINDLRR 794
Cdd:COG4886 358 LLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNTE 414
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
439-847 |
8.37e-20 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 93.46 E-value: 8.37e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 439 LKVLNASYNSITEIPKNCFPKLYELHTIDVSHNNISSIFNGVFQTLFSLRSIDLSHNSMREIKSSTFGTLPTLLEMDLSH 518
Cdd:COG4886 2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 519 NELVSVVRGSLAKLTSLRQLYLNNNqlEKLFQLPiSLNELYFSHNRLTNIPSGTWPvMNSLIYLDLSHNQLGDTlnGESF 598
Cdd:COG4886 82 LSLLLLGLTDLGDLTNLTELDLSGN--EELSNLT-NLESLDLSGNQLTDLPEELAN-LTNLKELDLSNNQLTDL--PEPL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 599 TGLLVVQRLKLQNNGISQPPKdAVAVMSTLQYLHLENNNITTLErSAFGKLPVLFELNLYGNQVKDISkrafegllqllt 678
Cdd:COG4886 156 GNLTNLKSLDLSNNQLTDLPE-ELGNLTNLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDLP------------ 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 679 lnlssngiqtlqnDIFVGLPSLRNLDLSFNSLTKLDNktngvLDDLLSLETLDLSHNRISfvtkkTFPSHQYIPyNLRNL 758
Cdd:COG4886 222 -------------EPLANLTNLETLDLSNNQLTDLPE-----LGNLTNLEELDLSNNQLT-----DLPPLANLT-NLKTL 277
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 759 NLSYNLMPILTYDITFGTKKLVRLDVSHNQINDLRRGVISNFTSLQSLDMSYNELSNLKSEEHIFDLPQNLSWLDLSHNK 838
Cdd:COG4886 278 DLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLN 357
|
....*....
gi 161077058 839 IYHLPFANL 847
Cdd:COG4886 358 LLSLLLTLL 366
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
200-593 |
4.56e-19 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 93.37 E-value: 4.56e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 200 LKTLDLHGNQLENLKRNQFKNLRELEVLDISHNQIKKLEAQHIADLTKLGWCNVSHNALSELSRGTFARNSVLKVLHLSH 279
Cdd:PLN00113 166 LKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVY 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 280 NQIARLDANSFRGMRFLRRLFLSDNVLTD-IGRGTFGsIARIGTIDLARNRLKKIEFQMFTQMNYVELLDLAENNIT-KI 357
Cdd:PLN00113 246 NNLTGPIPSSLGNLKNLQYLFLYQNKLSGpIPPSIFS-LQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTgKI 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 358 EKNSFKDIYQAIINVSHNAL--ELIETAAFENcvNITVLDLSHNRLANFSRRSFDETTFATYFQLSYNNLTnlAQIP--I 433
Cdd:PLN00113 325 PVALTSLPRLQVLQLWSNKFsgEIPKNLGKHN--NLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLE--GEIPksL 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 434 QNMTGLKVLNASYNSIT-EIPKNcFPKLYELHTIDVSHNNIS---------------------SIFNGVFQTLFS--LRS 489
Cdd:PLN00113 401 GACRSLRRVRLQDNSFSgELPSE-FTKLPLVYFLDISNNNLQgrinsrkwdmpslqmlslarnKFFGGLPDSFGSkrLEN 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 490 IDLSHNSMREIKSSTFGTLPTLLEMDLSHNELVSVVRGSLAKLTSLRQLYLNNNQLEKlfQLPIS------LNELYFSHN 563
Cdd:PLN00113 480 LDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSG--QIPASfsempvLSQLDLSQN 557
|
410 420 430
....*....|....*....|....*....|.
gi 161077058 564 RLT-NIPSGTWPVmNSLIYLDLSHNQLGDTL 593
Cdd:PLN00113 558 QLSgEIPKNLGNV-ESLVQVNISHNHLHGSL 587
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
532-887 |
1.72e-18 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 89.22 E-value: 1.72e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 532 LTSLRQLYLNNNQLEKLFQLPISLNELYFSHNRLTNIPSGTWPVMNSLIYLDLSHNQLGDTLNGESFTGLLVVQRLKLQN 611
Cdd:COG4886 2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 612 NGISQPPKDAVAVMSTLQYLHLENNNittlersAFGKLPVLFELNLYGNQVKDISkrafegllqlltlnlssngiqtlqn 691
Cdd:COG4886 82 LSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLP------------------------- 129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 692 DIFVGLPSLRNLDLSFNSLTKLDNktngVLDDLLSLETLDLSHNRISfvtkktfpshqYIPYNLRNLnlsynlmpiltyd 771
Cdd:COG4886 130 EELANLTNLKELDLSNNQLTDLPE----PLGNLTNLKSLDLSNNQLT-----------DLPEELGNL------------- 181
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 772 itfgtKKLVRLDVSHNQINDLRrGVISNFTSLQSLDMSYNELSNLKSEehIFDLPqNLSWLDLSHNKIYHLPfaNLVKVK 851
Cdd:COG4886 182 -----TNLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDLPEP--LANLT-NLETLDLSNNQLTDLP--ELGNLT 250
|
330 340 350
....*....|....*....|....*....|....*.
gi 161077058 852 SLKYVDLTNNSLEDVPASivGSMRNGSQVLLAGNPL 887
Cdd:COG4886 251 NLEELDLSNNQLTDLPPL--ANLTNLKTLDLSNNQL 284
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
192-524 |
6.79e-17 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 84.60 E-value: 6.79e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 192 ETFQPLRKLKTLDLHGNQLENLKrNQFKNLRELEVLDISHNQIKKLEAQhIADLTKLGWCNVSHNALSELSRGtFARNSV 271
Cdd:COG4886 107 EELSNLTNLESLDLSGNQLTDLP-EELANLTNLKELDLSNNQLTDLPEP-LGNLTNLKSLDLSNNQLTDLPEE-LGNLTN 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 272 LKVLHLSHNQIARLdANSFRGMRFLRRLFLSDNVLTDIGRgTFGSIARIGTIDLARNRLKKIEFqmFTQMNYVELLDLAE 351
Cdd:COG4886 184 LKELDLSNNQITDL-PEPLGNLTNLEELDLSGNQLTDLPE-PLANLTNLETLDLSNNQLTDLPE--LGNLTNLEELDLSN 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 352 NNITKIEKNSfkdiyqaiinvshnalelietaafeNCVNITVLDLSHNRLANFSRRSFDETTFAtyFQLSYNNLTNLAQI 431
Cdd:COG4886 260 NQLTDLPPLA-------------------------NLTNLKTLDLSNNQLTDLKLKELELLLGL--NSLLLLLLLLNLLE 312
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 432 PIQNMTGLKVLNASYNSITEIPKNCFPKLYELHTIDVSHNNISSIFNGVFQTLFSLRSIDLSHNSMREIKSSTFGTLPTL 511
Cdd:COG4886 313 LLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLL 392
|
330
....*....|...
gi 161077058 512 LEMDLSHNELVSV 524
Cdd:COG4886 393 LLTTTAGVLLLTL 405
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
199-735 |
8.55e-13 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 72.96 E-value: 8.55e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 199 KLKTLDLHGNQLENLKRNQFKNLRELEVLDISHNQIKKLEAQHIADLT-KLGWCNVSHNALS-ELSRGTFarnSVLKVLH 276
Cdd:PLN00113 70 RVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLSGPIPDDIFTTSsSLRYLNLSNNNFTgSIPRGSI---PNLETLD 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 277 LSHNQIA---RLDANSFRGMRFLRrlfLSDNVLTDIGRGTFGSIARIGTIDLARNRLKKIEFQMFTQMNYVELLDLAENN 353
Cdd:PLN00113 147 LSNNMLSgeiPNDIGSFSSLKVLD---LGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYNN 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 354 IT-KIEKnsfkDIYQaIINVSHnalelietaafencvnitvLDLSHNRLANFSRRSFDETTFATYFQLSYNNLTNlaQIP 432
Cdd:PLN00113 224 LSgEIPY----EIGG-LTSLNH-------------------LDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSG--PIP 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 433 --IQNMTGLKVLNASYNSIT-EIPKncfpKLYELHTIDVSH---NNISSIFNGVFQTLFSLRSIDLSHNSMREIKSSTFG 506
Cdd:PLN00113 278 psIFSLQKLISLDLSDNSLSgEIPE----LVIQLQNLEILHlfsNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKNLG 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 507 TLPTLLEMDLSHNELVSVVRGSLAKLTSLRQLYLNNNQLEKlfQLPISLN------ELYFSHNRLTNIPSGTWPVMNSLI 580
Cdd:PLN00113 354 KHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEG--EIPKSLGacrslrRVRLQDNSFSGELPSEFTKLPLVY 431
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 581 YLDLSHNQLGDTLNGESFTgLLVVQRLKLQNNGISQPPKDAVAVmSTLQYLHLENNNITTLERSAFGKLPVLFELNLYGN 660
Cdd:PLN00113 432 FLDISNNNLQGRINSRKWD-MPSLQMLSLARNKFFGGLPDSFGS-KRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSEN 509
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 161077058 661 QVKDISKRAFEGLLQLLTLNLSSNGIQTLQNDIFVGLPSLRNLDLSFNSLTkldNKTNGVLDDLLSLETLDLSHN 735
Cdd:PLN00113 510 KLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLS---GEIPKNLGNVESLVQVNISHN 581
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
486-738 |
1.68e-12 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 69.69 E-value: 1.68e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 486 SLRSIDLSHNSMREIKSST------FGTLPTLLEMDLSHNELVSVVRGSLAKLT---SLRQLYLNNNQLEK--------- 547
Cdd:cd00116 52 SLKELCLSLNETGRIPRGLqsllqgLTKGCGLQELDLSDNALGPDGCGVLESLLrssSLQELKLNNNGLGDrglrllakg 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 548 LFQLPISLNELYFSHNRLTNIP----SGTWPVMNSLIYLDLSHNQLGDTLngesftgllvVQRLKLqnngisqppkdAVA 623
Cdd:cd00116 132 LKDLPPALEKLVLGRNRLEGAScealAKALRANRDLKELNLANNGIGDAG----------IRALAE-----------GLK 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 624 VMSTLQYLHLENNNITTLERSAFG----KLPVLFELNLYGNQVkdiskrafegllqlltlnlSSNGIQTLQNDIFVGLPS 699
Cdd:cd00116 191 ANCNLEVLDLNNNGLTDEGASALAetlaSLKSLEVLNLGDNNL-------------------TDAGAAALASALLSPNIS 251
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 161077058 700 LRNLDLSFNSLTKLDNKT-NGVLDDLLSLETLDLSHNRIS 738
Cdd:cd00116 252 LLTLSLSCNDITDDGAKDlAEVLAEKESLLELDLRGNKFG 291
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
391-589 |
6.30e-12 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 69.73 E-value: 6.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 391 ITVLDLSHNRLanfsrRSFDETTFATYFQLSYNNlTNLAQIPIQNMTGLKVLNASYNSITEIPKNcFPKlyELHTIDVSH 470
Cdd:PRK15370 201 ITTLILDNNEL-----KSLPENLQGNIKTLYANS-NQLTSIPATLPDTIQEMELSINRITELPER-LPS--ALQSLDLFH 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 471 NNISSIFNGVFQtlfSLRSIDLSHNSMREI---------------KSSTF--GTLPTLLEMDLSHNELVSVVRGSLAKlt 533
Cdd:PRK15370 272 NKISCLPENLPE---ELRYLSVYDNSIRTLpahlpsgithlnvqsNSLTAlpETLPPGLKTLEAGENALTSLPASLPP-- 346
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 161077058 534 SLRQLYLNNNQLEKLFQ-LPISLNELYFSHNRLTNIPSGtwpVMNSLIYLDLSHNQL 589
Cdd:PRK15370 347 ELQVLDVSKNQITVLPEtLPPTITTLDVSRNALTNLPEN---LPAALQIMQASRNNL 400
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
631-849 |
1.48e-11 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 65.19 E-value: 1.48e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 631 LHLENNNITTLER-SAFGKLPVLFelnLYGNQvkdiskrafegllqlltlnlssngIQTLQNdiFVGLPSLRNLDLSFNS 709
Cdd:cd21340 7 LYLNDKNITKIDNlSLCKNLKVLY---LYDNK------------------------ITKIEN--LEFLTNLTHLYLQNNQ 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 710 LTKLDNktngvLDDLLSLETLDLSHNRISFVtkktfpSHQYIPYNLRNLNLSYNLMPI---LTYD---ITFGTKKLVRLD 783
Cdd:cd21340 58 IEKIEN-----LENLVNLKKLYLGGNRISVV------EGLENLTNLEELHIENQRLPPgekLTFDprsLAALSNSLRVLN 126
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 161077058 784 VSHNQINDLRrgVISNFTSLQSLDMSYNELSNLKS-EEHIFDLPQnLSWLDLSHNkiyhlPFANLVK 849
Cdd:cd21340 127 ISGNNIDSLE--PLAPLRNLEQLDASNNQISDLEElLDLLSSWPS-LRELDLTGN-----PVCKKPK 185
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
486-545 |
1.71e-10 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 57.53 E-value: 1.71e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 486 SLRSIDLSHNSMREIKSSTFGTLPTLLEMDLSHNELVSVVRGSLAKLTSLRQLYLNNNQL 545
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
275-495 |
3.49e-10 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 60.96 E-value: 3.49e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 275 LHLSHNQIARLDAnsFRGMRFLRRLFLSDNVLTDIGrgTFGSIARIGTIDLARNRLKKIEfqMFTQMNYVELLDLAENNI 354
Cdd:cd21340 7 LYLNDKNITKIDN--LSLCKNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKIE--NLENLVNLKKLYLGGNRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 355 TKIEknsfkdiyqaiinvshnalelietaAFENCVNITVLDLSHNRLANFSRRSFDETTFATyfqLSYNnltnlaqipiq 434
Cdd:cd21340 81 SVVE-------------------------GLENLTNLEELHIENQRLPPGEKLTFDPRSLAA---LSNS----------- 121
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 161077058 435 nmtgLKVLNASYNSITEIpkNCFPKLYELHTIDVSHNNISSI--FNGVFQTLFSLRSIDLSHN 495
Cdd:cd21340 122 ----LRVLNISGNNIDSL--EPLAPLRNLEQLDASNNQISDLeeLLDLLSSWPSLRELDLTGN 178
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
484-545 |
3.86e-09 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 60.60 E-value: 3.86e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 161077058 484 LFSLRSIDLSHNSMREIKSSTFGTLPTLLEMDLSHNELVSVVRGSLAKLTSLRQLYLNNNQL 545
Cdd:PLN03150 441 LRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSL 502
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
606-887 |
4.38e-09 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 60.48 E-value: 4.38e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 606 RLKLQNNGISQPPKDAVAVMSTLQylhLENNNITTLERsafgklpvlfelNLYGNqVKDISKRAfegLLQLLTLNLSSNG 685
Cdd:PRK15370 182 ELRLKILGLTTIPACIPEQITTLI---LDNNELKSLPE------------NLQGN-IKTLYANS---NQLTSIPATLPDT 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 686 IQTLQNDI--FVGLP-----SLRNLDLSFNSLTKL-DNKTNGvlddllsLETLDLSHNRIsfvtkKTFPSHqyIPYNLRN 757
Cdd:PRK15370 243 IQEMELSInrITELPerlpsALQSLDLFHNKISCLpENLPEE-------LRYLSVYDNSI-----RTLPAH--LPSGITH 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 758 LNLSYNLMPILTYDITFGTKKLVRLDvshNQINDLRRGVISnftSLQSLDMSYNELSNLKSEehifdLPQNLSWLDLSHN 837
Cdd:PRK15370 309 LNVQSNSLTALPETLPPGLKTLEAGE---NALTSLPASLPP---ELQVLDVSKNQITVLPET-----LPPTITTLDVSRN 377
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 161077058 838 KIYHLPfANLvkVKSLKYVDLTNNSLEDVPASIVGSMRNGSQ---VLLAGNPL 887
Cdd:PRK15370 378 ALTNLP-ENL--PAALQIMQASRNNLVRLPESLPHFRGEGPQptrIIVEYNPF 427
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
198-258 |
7.12e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 52.91 E-value: 7.12e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 161077058 198 RKLKTLDLHGNQLENLKRNQFKNLRELEVLDISHNQIKKLEAQHIADLTKLGWCNVSHNAL 258
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
191-359 |
2.62e-08 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 55.56 E-value: 2.62e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 191 IETFQPLRKLKTLDLHGNQLENLKrnQFKNLRELEVLDISHNQIKKLE-AQHIADLTKLgwcNVSHNALSELSrGtFARN 269
Cdd:cd21340 17 IDNLSLCKNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKIEnLENLVNLKKL---YLGGNRISVVE-G-LENL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 270 SVLKVLHLSHNQIAR-----LDANSFRGM-RFLRRLFLSDNVLTDIgrGTFGSIARIGTIDLARNRLKKIE--FQMFTQM 341
Cdd:cd21340 90 TNLEELHIENQRLPPgekltFDPRSLAALsNSLRVLNISGNNIDSL--EPLAPLRNLEQLDASNNQISDLEelLDLLSSW 167
|
170
....*....|....*...
gi 161077058 342 NYVELLDLAENNITKIEK 359
Cdd:cd21340 168 PSLRELDLTGNPVCKKPK 185
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
245-306 |
3.18e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 50.99 E-value: 3.18e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 161077058 245 LTKLgwcNVSHNALSELSRGTFARNSVLKVLHLSHNQIARLDANSFRGMRFLRRLFLSDNVL 306
Cdd:pfam13855 3 LRSL---DLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
626-710 |
9.08e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 49.83 E-value: 9.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 626 STLQYLHLENNNITTLERSAFGKLPVLFELNLYGNQVKDISKRAfegllqlltlnlssngiqtlqndiFVGLPSLRNLDL 705
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGA------------------------FSGLPSLRYLDL 56
|
....*
gi 161077058 706 SFNSL 710
Cdd:pfam13855 57 SGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
544-814 |
9.61e-08 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 55.05 E-value: 9.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 544 QLEKLFQLPISLNELYFSHNRLTNIPSGTWPVMNSLI------YLDLSHNQLGDTLNG--ESFTGLLVVQRLKLQNNGIS 615
Cdd:cd00116 42 ALASALRPQPSLKELCLSLNETGRIPRGLQSLLQGLTkgcglqELDLSDNALGPDGCGvlESLLRSSSLQELKLNNNGLG 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 616 QPPKDAVA-----VMSTLQYLHLENNNIT--TLER--SAFGKLPVLFELNLYGNQVKDiskrafegllqlltlnlssNGI 686
Cdd:cd00116 122 DRGLRLLAkglkdLPPALEKLVLGRNRLEgaSCEAlaKALRANRDLKELNLANNGIGD-------------------AGI 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 687 QTLqndiFVGLPS---LRNLDLSFNSLTKL-DNKTNGVLDDLLSLETLDLSHNRISFVTKKTFPShQYIPYN--LRNLNL 760
Cdd:cd00116 183 RAL----AEGLKAncnLEVLDLNNNGLTDEgASALAETLASLKSLEVLNLGDNNLTDAGAAALAS-ALLSPNisLLTLSL 257
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 161077058 761 SYNlmpiltyDITF-GTKKLvrldvshnqindlrRGVISNFTSLQSLDMSYNELS 814
Cdd:cd00116 258 SCN-------DITDdGAKDL--------------AEVLAEKESLLELDLRGNKFG 291
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
682-737 |
1.64e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 49.06 E-value: 1.64e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 161077058 682 SSNGIQTLQNDIFVGLPSLRNLDLSFNSLTKLDnktNGVLDDLLSLETLDLSHNRI 737
Cdd:pfam13855 9 SNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLS---PGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
437-495 |
1.93e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 48.67 E-value: 1.93e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 161077058 437 TGLKVLNASYNSITEIPKNCFPKLYELHTIDVSHNNISSIFNGVFQTLFSLRSIDLSHN 495
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
778-839 |
2.05e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 48.67 E-value: 2.05e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 161077058 778 KLVRLDVSHNQINDLRRGVISNFTSLQSLDMSYNELSNLkSEEHIFDLPqNLSWLDLSHNKI 839
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTL-SPGAFSGLP-SLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
462-521 |
2.33e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 48.67 E-value: 2.33e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 462 ELHTIDVSHNNISSIFNGVFQTLFSLRSIDLSHNSMREIKSSTFGTLPTLLEMDLSHNEL 521
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
201-545 |
2.68e-07 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 53.90 E-value: 2.68e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 201 KTLDLHGNQLENLK-RNQFKNLRELEVLDISHNQIKKLEAQHIADLTKlgwcnvshnalselsrgtfaRNSVLKVLHLSH 279
Cdd:cd00116 1 LQLSLKGELLKTERaTELLPKLLCLQVLRLEGNTLGEEAAKALASALR--------------------PQPSLKELCLSL 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 280 NQIARLDANSFRGMRF------LRRLFLSDNVLTDIGRGTFgsiarigtidlarnrlkkiefQMFTQMNYVELLDLAENN 353
Cdd:cd00116 61 NETGRIPRGLQSLLQGltkgcgLQELDLSDNALGPDGCGVL---------------------ESLLRSSSLQELKLNNNG 119
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 354 ITKieknsfkdiyqaiinvshNALELIETAAFENCVNITVLDLSHNRLANFSrrsfdettfatyfqlsynnLTNLAQIPI 433
Cdd:cd00116 120 LGD------------------RGLRLLAKGLKDLPPALEKLVLGRNRLEGAS-------------------CEALAKALR 162
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 434 QNMTgLKVLNASYNSITE--IPKNC--FPKLYELHTIDVSHNNI----SSIFNGVFQTLFSLRSIDLSHNS-----MREI 500
Cdd:cd00116 163 ANRD-LKELNLANNGIGDagIRALAegLKANCNLEVLDLNNNGLtdegASALAETLASLKSLEVLNLGDNNltdagAAAL 241
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 161077058 501 KSSTFGTLPTLLEMDLSHNEL----VSVVRGSLAKLTSLRQLYLNNNQL 545
Cdd:cd00116 242 ASALLSPNISLLTLSLSCNDItddgAKDLAEVLAEKESLLELDLRGNKF 290
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
516-763 |
2.90e-07 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 54.70 E-value: 2.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 516 LSHNELVSVVRGSLAkltSLRQLYLNNNQLEKLFQ-LPISLNELYFSHNRLTNIPSgtwPVMNSLIYLDLSHNQLG---D 591
Cdd:PRK15370 206 LDNNELKSLPENLQG---NIKTLYANSNQLTSIPAtLPDTIQEMELSINRITELPE---RLPSALQSLDLFHNKISclpE 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 592 TLNGEsftgllvVQRLKLQNNGISQPPKDavaVMSTLQYLHLENNNITTLERSafgkLPVLFELNLYGNqvkdiskrafe 671
Cdd:PRK15370 280 NLPEE-------LRYLSVYDNSIRTLPAH---LPSGITHLNVQSNSLTALPET----LPPGLKTLEAGE----------- 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 672 gllqlltlnlssNGIQTLQNDIfvgLPSLRNLDLSFNSLTkldnktngVLDDLL--SLETLDLSHNRISfvtkkTFPSHq 749
Cdd:PRK15370 335 ------------NALTSLPASL---PPELQVLDVSKNQIT--------VLPETLppTITTLDVSRNALT-----NLPEN- 385
|
250
....*....|....
gi 161077058 750 yIPYNLRNLNLSYN 763
Cdd:PRK15370 386 -LPAALQIMQASRN 398
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
175-234 |
3.31e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 48.29 E-value: 3.31e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 175 SLGIIRVTNGNLSDLPIETFQPLRKLKTLDLHGNQLENLKRNQFKNLRELEVLDISHNQI 234
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
272-330 |
3.80e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 47.90 E-value: 3.80e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 161077058 272 LKVLHLSHNQIARLDANSFRGMRFLRRLFLSDNVLTDIGRGTFGSIARIGTIDLARNRL 330
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
469-865 |
6.05e-07 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 53.26 E-value: 6.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 469 SHNNISSIFNGVFQTLFSLRSIDLS-------HNSMREIKSSTFGTLPTLLEMDLSHNE----------LVSVVRGSLAK 531
Cdd:COG5238 17 SANPATTEQSELTKRATIVNLRSYHlhggailLARYLQSRSSITQYLRFEGQGDPGLNPvalekaaeafPTQLLVVDWEG 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 532 LTSLRQLYLNNNQLEKLFQLP----------ISLNELYFSHNRLTNIPSGTW--PVMNSLIYLDLSHNQLGDTLNGESFT 599
Cdd:COG5238 97 AEEVSPVALAETATAVATPPPdlrrimaktlEDSLILYLALPRRINLIQVLKdpLGGNAVHLLGLAARLGLLAAISMAKA 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 600 GLLV-VQRLKLQNNGISQPPKDAVAVmstlqylHLE-NNNITTLErsafgklpvlfelnLYGNQVKDISKRAFegllqll 677
Cdd:COG5238 177 LQNNsVETVYLGCNQIGDEGIEELAE-------ALTqNTTVTTLW--------------LKRNPIGDEGAEIL------- 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 678 tlnlssngIQTLQndifvGLPSLRNLDLSFNSLTklDNKTNGVLDDLL---SLETLDLSHNRISFVTKKTFPSHQYIPYN 754
Cdd:COG5238 229 --------AEALK-----GNKSLTTLDLSNNQIG--DEGVIALAEALKnntTVETLYLSGNQIGAEGAIALAKALQGNTT 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 755 LRNLNLSYNlmpiltyDITF-----------GTKKLVRLDVSHNQINDlrRGVISNFTSLQ------SLDMSYNELSNLK 817
Cdd:COG5238 294 LTSLDLSVN-------RIGDegaialaeglqGNKTLHTLNLAYNGIGA--QGAIALAKALQenttlhSLDLSDNQIGDEG 364
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 161077058 818 SEE--HIFDLPQNLSWLDLSHNKIYHLPFANLVK---VKSLKYVDLTNNSLED 865
Cdd:COG5238 365 AIAlaKYLEGNTTLRELNLGKNNIGKQGAEALIDalqTNRLHTLILDGNLIGA 417
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
554-614 |
1.64e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 46.36 E-value: 1.64e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 161077058 554 SLNELYFSHNRLTNIPSGTWPVMNSLIYLDLSHNQLgDTLNGESFTGLLVVQRLKLQNNGI 614
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL-TTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
698-765 |
1.74e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.98 E-value: 1.74e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 161077058 698 PSLRNLDLSFNSLTKLDNKTngvLDDLLSLETLDLSHNRISFVTKKTFpshQYIPyNLRNLNLSYNLM 765
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGA---FKGLSNLKVLDLSNNLLTTLSPGAF---SGLP-SLRYLDLSGNRL 61
|
|
| LRR_5 |
pfam13306 |
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ... |
355-505 |
3.84e-06 |
|
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.
Pssm-ID: 463839 [Multi-domain] Cd Length: 127 Bit Score: 47.15 E-value: 3.84e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 355 TKIEKNSFKDIYQAIINVSHNaLELIETAAFENCVNITVLDLShNRLANFSRRSFdettfatyfqlSYNNLTNLAqIPiq 434
Cdd:pfam13306 1 TSIGSYAFYNCSLTSITIPSS-LTSIGEYAFSNCTSLKSITLP-SSLTSIGSYAF-----------YNCSLTSIT-IP-- 64
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 161077058 435 nmtglkvlnasyNSITEIPKNCFPKLYELHTIDVShNNISSIFNGVFQTlFSLRSIDLShNSMREIKSSTF 505
Cdd:pfam13306 65 ------------SSLTSIGEYAFSNCSNLKSITLP-SNLTSIGSYAFSN-CSLKSITIP-SSVTTIGSYAF 120
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
423-616 |
6.57e-06 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 50.55 E-value: 6.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 423 NNLTNLAQIPiqnmTGLKVLNASYNSITEIPknCFPKlyELHTIDVSHNNISSIfngvfQTLFS-LRSIDLSHNSMreik 501
Cdd:PRK15387 292 NQLTSLPVLP----PGLQELSVSDNQLASLP--ALPS--ELCKLWAYNNQLTSL-----PTLPSgLQELSVSDNQL---- 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 502 sSTFGTLPTLLEMDLSHNELVSvvrgSLAKLTS-LRQLYLNNNQLEKLFQLPISLNELYFSHNRLTNIPSgtwpVMNSLI 580
Cdd:PRK15387 355 -ASLPTLPSELYKLWAYNNRLT----SLPALPSgLKELIVSGNRLTSLPVLPSELKELMVSGNRLTSLPM----LPSGLL 425
|
170 180 190
....*....|....*....|....*....|....*.
gi 161077058 581 YLDLSHNQLgdTLNGESFTGLLVVQRLKLQNNGISQ 616
Cdd:PRK15387 426 SLSVYRNQL--TRLPESLIHLSSETTVNLEGNPLSE 459
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
698-898 |
6.93e-06 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 48.24 E-value: 6.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 698 PSLRNLDLSFNSLTKLDNktngvLDDLLSLETLDLSHNRISFVTkktfpshqyipyNLRNLnlsynlmpiltyditfgtK 777
Cdd:cd21340 24 KNLKVLYLYDNKITKIEN-----LEFLTNLTHLYLQNNQIEKIE------------NLENL------------------V 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 778 KLVRLDVSHNQINdlrrgVISNF---TSLQSLDMSYNELSNlkSEEHIFD------LPQNLSWLDLSHNKIYHLpfANLV 848
Cdd:cd21340 69 NLKKLYLGGNRIS-----VVEGLenlTNLEELHIENQRLPP--GEKLTFDprslaaLSNSLRVLNISGNNIDSL--EPLA 139
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 161077058 849 KVKSLKYVDLTNNSLEDVP--ASIVGSMRNGSQVLLAGNPLhcgcnARPLKY 898
Cdd:cd21340 140 PLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGNPV-----CKKPKY 186
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
438-738 |
1.23e-05 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 49.39 E-value: 1.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 438 GLKVLNASYNSITEIPkNCFPKlyELHTIDVSHNNISSIFngvfQTLFSLRSIDLSHNSMREIKSSTfgtlPTLLEMDLS 517
Cdd:PRK15387 202 GNAVLNVGESGLTTLP-DCLPA--HITTLVIPDNNLTSLP----ALPPELRTLEVSGNQLTSLPVLP----PGLLELSIF 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 518 HNELVSVVrgslAKLTSLRQLYLNNNQLEKLFQLPISLNELYFSHNRLTNIPSgtwpVMNSLIYLDLSHNQLGDTLNGES 597
Cdd:PRK15387 271 SNPLTHLP----ALPSGLCKLWIFGNQLTSLPVLPPGLQELSVSDNQLASLPA----LPSELCKLWAYNNQLTSLPTLPS 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 598 ftGLlvvQRLKLQNNGISQPPkdavAVMSTLQYLHLENNNITTLERSAFGklpvLFELNLYGNQVKDISKRAFEgllqLL 677
Cdd:PRK15387 343 --GL---QELSVSDNQLASLP----TLPSELYKLWAYNNRLTSLPALPSG----LKELIVSGNRLTSLPVLPSE----LK 405
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 161077058 678 TLNLSSNGIQTLQNdifvgLPS-LRNLDLSFNSLTKLDNKtngvLDDLLSLETLDLSHNRIS 738
Cdd:PRK15387 406 ELMVSGNRLTSLPM-----LPSgLLSLSVYRNQLTRLPES----LIHLSSETTVNLEGNPLS 458
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
529-738 |
1.35e-05 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 47.47 E-value: 1.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 529 LAKLTslrQLYLNNNQLEKL--FQLPISLNELYFSHNRLTNIPsgtwpvmnsliyldlshnqlgdtlNGESFTGLlvvQR 606
Cdd:cd21340 1 LKRIT---HLYLNDKNITKIdnLSLCKNLKVLYLYDNKITKIE------------------------NLEFLTNL---TH 50
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 607 LKLQNNGISqppK-DAVAVMSTLQYLHLENNNITTLErsAFGKLPVLFELNLYGNQVKDISKRAFEGLLQLLTLNL---- 681
Cdd:cd21340 51 LYLQNNQIE---KiENLENLVNLKKLYLGGNRISVVE--GLENLTNLEELHIENQRLPPGEKLTFDPRSLAALSNSlrvl 125
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 161077058 682 --SSNGIQTLQNdiFVGLPSLRNLDLSFNSLTKLDnKTNGVLDDLLSLETLDLSHNRIS 738
Cdd:cd21340 126 niSGNNIDSLEP--LAPLRNLEQLDASNNQISDLE-ELLDLLSSWPSLRELDLTGNPVC 181
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
416-473 |
1.38e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 43.67 E-value: 1.38e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 161077058 416 TYFQLSYNNLTNLAQIPIQNMTGLKVLNASYNSITEIPKNCFPKLYELHTIDVSHNNI 473
Cdd:pfam13855 4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
529-667 |
1.68e-05 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 47.09 E-value: 1.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 529 LAKLTSLRQLYLNNNQLEKL--FQLPISLNELYFSHNR------LTNIPsgtwpvmnSLIYLDLSHNQL--GDTL--NGE 596
Cdd:cd21340 42 LEFLTNLTHLYLQNNQIEKIenLENLVNLKKLYLGGNRisvvegLENLT--------NLEELHIENQRLppGEKLtfDPR 113
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 161077058 597 SFTGLLV-VQRLKLQNNGISQPpkDAVAVMSTLQYLHLENNNITTLER--SAFGKLPVLFELNLYGNQVKDISK 667
Cdd:cd21340 114 SLAALSNsLRVLNISGNNIDSL--EPLAPLRNLEQLDASNNQISDLEEllDLLSSWPSLRELDLTGNPVCKKPK 185
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
604-662 |
1.71e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 43.28 E-value: 1.71e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 161077058 604 VQRLKLQNNGISQPPKDAVAVMSTLQYLHLENNNITTLERSAFGKLPVLFELNLYGNQV 662
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
582-866 |
2.10e-05 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 47.74 E-value: 2.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 582 LDLSHNQLGDTLNGESFTGLLVVQRLKLQNNGISQPPKDAVAVM----STLQYLHLENNNITTLER------SAFGKLPV 651
Cdd:cd00116 3 LSLKGELLKTERATELLPKLLCLQVLRLEGNTLGEEAAKALASAlrpqPSLKELCLSLNETGRIPRglqsllQGLTKGCG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 652 LFELNLYGNQVKDISKRAFEgllqlltlnlssngiQTLQNdifvglPSLRNLDLSFNSL--TKLDNKTNGVLDDLLSLET 729
Cdd:cd00116 83 LQELDLSDNALGPDGCGVLE---------------SLLRS------SSLQELKLNNNGLgdRGLRLLAKGLKDLPPALEK 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 730 LDLSHNRIS----FVTKKTFPSHQyipynlrnlnlsynlmpiltyditfgtkKLVRLDVSHNQIND-----LRRGVISNf 800
Cdd:cd00116 142 LVLGRNRLEgascEALAKALRANR----------------------------DLKELNLANNGIGDagiraLAEGLKAN- 192
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 161077058 801 TSLQSLDMSYNELS--NLKSEEHIFDLPQNLSWLDLSHNKI-----YHLPFANLVKVKSLKYVDLTNNSLEDV 866
Cdd:cd00116 193 CNLEVLDLNNNGLTdeGASALAETLASLKSLEVLNLGDNNLtdagaAALASALLSPNISLLTLSLSCNDITDD 265
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
726-813 |
4.13e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 42.13 E-value: 4.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 726 SLETLDLSHNRISFVTKKTFpshqyipynlrnlnlsynlmpiltyditFGTKKLVRLDVSHNQINDLRRGVISNFTSLQS 805
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAF----------------------------KGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRY 53
|
....*...
gi 161077058 806 LDMSYNEL 813
Cdd:pfam13855 54 LDLSGNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
347-569 |
4.54e-05 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 45.93 E-value: 4.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 347 LDLAENNITKIEK-NSFKdiyqaiiNVSH-----NALELIEtaAFENCVNITVLDLSHNRLanfsRRsfdettfatyfql 420
Cdd:cd21340 7 LYLNDKNITKIDNlSLCK-------NLKVlylydNKITKIE--NLEFLTNLTHLYLQNNQI----EK------------- 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 421 synnLTNLaqipiQNMTGLKVLNASYNSITEIP--KNCfPKLYELHtidVSHNNISSifnGVfQTLFSLRSIdlshnsmr 498
Cdd:cd21340 61 ----IENL-----ENLVNLKKLYLGGNRISVVEglENL-TNLEELH---IENQRLPP---GE-KLTFDPRSL-------- 115
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 161077058 499 eiksstFGTLPTLLEMDLSHNELVSVvrGSLAKLTSLRQLYLNNNQLEK-------LFQLPiSLNELYFSHNRLTNIP 569
Cdd:cd21340 116 ------AALSNSLRVLNISGNNIDSL--EPLAPLRNLEQLDASNNQISDleelldlLSSWP-SLRELDLTGNPVCKKP 184
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
191-361 |
5.08e-05 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 47.09 E-value: 5.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 191 IETFQPLRKLKTLDLHGNQL---------ENLKRNqfknlRELEVLDISHNQIkklEAQHIADLTKlgwcnvshnalsel 261
Cdd:COG5238 229 AEALKGNKSLTTLDLSNNQIgdegvialaEALKNN-----TTVETLYLSGNQI---GAEGAIALAK-------------- 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 262 srgTFARNSVLKVLHLSHNQI----ARLDANSFRGMRFLRRLFLSDNVLTDIG-RGTFGSI---ARIGTIDLARNRLKK- 332
Cdd:COG5238 287 ---ALQGNTTLTSLDLSVNRIgdegAIALAEGLQGNKTLHTLNLAYNGIGAQGaIALAKALqenTTLHSLDLSDNQIGDe 363
|
170 180 190
....*....|....*....|....*....|..
gi 161077058 333 --IEFQMFTQMN-YVELLDLAENNITKIEKNS 361
Cdd:COG5238 364 gaIALAKYLEGNtTLRELNLGKNNIGKQGAEA 395
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
180-310 |
2.14e-04 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 44.65 E-value: 2.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 180 RVTNGNLSDLPiETFQPLRKLKTLDLHGNQL-----ENLKRNqFKNLRELEVLDISHNQIKKLEAQHIADLTK------- 247
Cdd:cd00116 148 RLEGASCEALA-KALRANRDLKELNLANNGIgdagiRALAEG-LKANCNLEVLDLNNNGLTDEGASALAETLAslkslev 225
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 161077058 248 --LGWCNVSHNALSELSRGTFARNSVLKVLHLSHNQIARLDANSFRG----MRFLRRLFLSDNVLTDIG 310
Cdd:cd00116 226 lnLGDNNLTDAGAAALASALLSPNISLLTLSLSCNDITDDGAKDLAEvlaeKESLLELDLRGNKFGEEG 294
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
322-401 |
5.76e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 39.04 E-value: 5.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 322 TIDLARNRLKKIEFQMFTQMNYVELLDLAENNITKIEKNsfkdiyqaiinvshnalelietaAFENCVNITVLDLSHNRL 401
Cdd:pfam13855 5 SLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPG-----------------------AFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
296-354 |
5.82e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 39.04 E-value: 5.82e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 161077058 296 LRRLFLSDNVLTDIGRGTFGSIARIGTIDLARNRLKKIEFQMFTQMNYVELLDLAENNI 354
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
369-425 |
1.22e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 38.27 E-value: 1.22e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 161077058 369 IINVSHNALELIETAAFENCVNITVLDLSHNRLANFSRRSFDETTFATYFQLSYNNL 425
Cdd:pfam13855 5 SLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
188-356 |
2.77e-03 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 41.19 E-value: 2.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 188 DLPIETFQPLRKLKTLDLHGNQLENLKRNQFKNLR---ELEVLDISHNQIKKLEAQHIA--------DLTK--LGWCNVS 254
Cdd:cd00116 71 QSLLQGLTKGCGLQELDLSDNALGPDGCGVLESLLrssSLQELKLNNNGLGDRGLRLLAkglkdlppALEKlvLGRNRLE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 255 HNALSELSrGTFARNSVLKVLHLSHNQIA--------------------RLDANSFR--GM----------RFLRRLFLS 302
Cdd:cd00116 151 GASCEALA-KALRANRDLKELNLANNGIGdagiralaeglkancnlevlDLNNNGLTdeGAsalaetlaslKSLEVLNLG 229
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 161077058 303 DNVLTDIGRGTFGSIARIG-----TIDLARNRLKKIEFQMFTQ----MNYVELLDLAENNITK 356
Cdd:cd00116 230 DNNLTDAGAAALASALLSPnisllTLSLSCNDITDDGAKDLAEvlaeKESLLELDLRGNKFGE 292
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
777-890 |
3.50e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 41.34 E-value: 3.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 777 KKLVRLDVSHNQIndlrRGVIS----NFTSLQSLDMSYNELSNLkseehifdLPQNLSwldlshnkiyhlpfanlvKVKS 852
Cdd:PLN03150 442 RHLQSINLSGNSI----RGNIPpslgSITSLEVLDLSYNSFNGS--------IPESLG------------------QLTS 491
|
90 100 110
....*....|....*....|....*....|....*....
gi 161077058 853 LKYVDLTNNSLE-DVPASIVGSMRNGSQVLLAGNPLHCG 890
Cdd:PLN03150 492 LRILNLNGNSLSgRVPAALGGRLLHRASFNFTDNAGLCG 530
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
509-565 |
3.59e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 36.73 E-value: 3.59e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 161077058 509 PTLLEMDLSHNELVSVVRGSLAKLTSLRQLYLNNNQLEKL----FQLPISLNELYFSHNRL 565
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLspgaFSGLPSLRYLDLSGNRL 61
|
|
| LRR_5 |
pfam13306 |
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ... |
280-392 |
3.95e-03 |
|
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.
Pssm-ID: 463839 [Multi-domain] Cd Length: 127 Bit Score: 38.68 E-value: 3.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077058 280 NQIARLDANSFRGMRFLRRLFLSDNvLTDIGRGTFGSIArIGTIDLaRNRLKKIEFQMFTQMNYVELLDLaENNITKIEK 359
Cdd:pfam13306 20 SSLTSIGEYAFSNCTSLKSITLPSS-LTSIGSYAFYNCS-LTSITI-PSSLTSIGEYAFSNCSNLKSITL-PSNLTSIGS 95
|
90 100 110
....*....|....*....|....*....|...
gi 161077058 360 NSFKDIYQAIINVShNALELIETAAFENCVNIT 392
Cdd:pfam13306 96 YAFSNCSLKSITIP-SSVTTIGSYAFSNCSNLK 127
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
197-259 |
4.80e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 40.95 E-value: 4.80e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 161077058 197 LRKLKTLDLHGNQLENLKRNQFKNLRELEVLDISHNQIKKLEAQHIADLTKLGWCNVSHNALS 259
Cdd:PLN03150 441 LRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLS 503
|
|
| |
