|
Name |
Accession |
Description |
Interval |
E-value |
| DEXHc_DHX32 |
cd17977 |
DEXH-box helicase domain of DEAH-box helicase 32; DEAH-box helicase 32 (DHX32) belongs to the ... |
62-237 |
1.41e-109 |
|
DEXH-box helicase domain of DEAH-box helicase 32; DEAH-box helicase 32 (DHX32) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350735 [Multi-domain] Cd Length: 176 Bit Score: 330.25 E-value: 1.41e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 62 LPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQWCAEYCLSIHYQHGGVICTQAHKQTAVQLALRVADEMDVNIGHE 141
Cdd:cd17977 1 LPVWEAKYEFMESLAHNQIVIVSGDAKTGKSSQIPQWCAEYCLSAHYQHGVVVCTQVHKQTAVWLALRVADEMDVNIGHE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 142 VGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIVNCSPLL 221
Cdd:cd17977 81 VGYVIPFENCCTNETILRYCTDDMLLREMMSDPLLESYGVIILDDAHERTVSTDVLLGLLKDVLLSRPELKLVIITCPHL 160
|
170
....*....|....*.
gi 2214414571 222 TSKLSSYYGDVPVIEV 237
Cdd:cd17977 161 SSKLLSYYGNVPLIEV 176
|
|
| HrpA |
COG1643 |
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]; |
73-695 |
1.88e-59 |
|
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 441249 [Multi-domain] Cd Length: 836 Bit Score: 215.72 E-value: 1.88e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 73 ESLLQNQVVVVSGDSKCGKSSQVPQWCAEyclSIHYQHGGVICTQ----AhkqtAVQLALRVADEMDVNIGHEVGYVIPF 148
Cdd:COG1643 21 AALRAHQVVVLAAPPGAGKTTQLPLALLE---LGWGAGGRIGMLEprrlA----ARAAAERMAEELGEPVGETVGYRVRF 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 149 ENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATD--------VLLGLlkdvllaRPELKLIVncspl 220
Cdd:COG1643 94 EDKVSAATRIEVVTEGILLRELQRDPELEGVDTVIFDEFHERSLNADlllallldLQPAL-------RPDLKLLV----- 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 221 lTS------KLSSYYGDVPVIEV--RNkHPVEVVYL--SGAQKDSFESVIRLIFEIHRSGEkGDVVVFLACEQDIEKTYE 290
Cdd:COG1643 162 -MSatldaeRFARLLGDAPVIESsgRT-YPVEVRYRplPADERDLEDAVADAVREALAEEP-GDILVFLPGEREIRRTAE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 291 LvcqegsnLNPDVG-DLVVIPLY----PKEKCSLFRPVDETekrcqvyQRRVVLTTSCGESliwSHTV---KFVIDVGLE 362
Cdd:COG1643 239 A-------LRGRLPpDTEILPLYgrlsAAEQDRAFAPAPHG-------RRRIVLATNIAET---SLTVpgiRYVIDSGLA 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 363 RRQVYNPRIRANSLVLQPISQSQAEIRKqllGS----SPsGKLFCLYTEE-FASkdMRPLKPAEMQEANLTSMVLFMKR- 436
Cdd:COG1643 302 RIPRYDPRSGVTRLPTERISQASANQRA---GRagrlAP-GICYRLWSEEdFAR--RPAFTDPEILRADLASLILELAAw 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 437 --VDIAGLgrcDFMNRPAPESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEMLTIAAMV 514
Cdd:COG1643 376 glGDPEDL---PFLDPPPARAIADARALLQELGALDADGRLTPLGRALARLPLDPRLARMLLAAAELGCLREAAILAALL 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 515 TAPscflHVPHGAeeaavtcwktflhPEGDHFTLINVYNAYQDTVLNsanehcvemwchdcFLSCSALRmadviraELLE 594
Cdd:COG1643 453 SER----DPRRGA-------------AGSDLLARLNLWRRLREQQRE--------------FLSYLRLR-------EWRD 494
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 595 IIKRIELPYAEPAFGSKENGLNIKKALLSGYFMQIARDVDGSGNYLmLTHKQVAQLHPLSsySITKKmpEWVLfhqfsIS 674
Cdd:COG1643 495 LARQLRRLLGEGANEEPADYEAIGLLLALAYPDRIARRRGEGGRYL-LARGRGAALFPGS--PLAKK--EWLV-----AA 564
|
650 660
....*....|....*....|....*..
gi 2214414571 675 E------NNYIRVASAVSPELFMQLVP 695
Cdd:COG1643 565 ElvggaaEARIRLAAPIDPEWLEELAA 591
|
|
| PRK11131 |
PRK11131 |
ATP-dependent RNA helicase HrpA; Provisional |
60-688 |
2.59e-50 |
|
ATP-dependent RNA helicase HrpA; Provisional
Pssm-ID: 182986 [Multi-domain] Cd Length: 1294 Bit Score: 191.04 E-value: 2.59e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 60 EELPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQWCAEYCLSIHyqhgGVIC-TQAHKQTAVQLALRVADEMDVNI 138
Cdd:PRK11131 71 ENLPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICLELGRGVK----GLIGhTQPRRLAARTVANRIAEELETEL 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 139 GHEVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIVNCS 218
Cdd:PRK11131 147 GGCVGYKVRFNDQVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFILGYLKELLPRRPDLKVIITSA 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 219 PLLTSKLSSYYGDVPVIEVRNK-HPVEVVY--LSGAQKDSFESVIRLIF----EIHRSGeKGDVVVFLACEQDIEKTYEL 291
Cdd:PRK11131 227 TIDPERFSRHFNNAPIIEVSGRtYPVEVRYrpIVEEADDTERDQLQAIFdavdELGREG-PGDILIFMSGEREIRDTADA 305
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 292 VCQEgsnlnpDVGDLVVIPLYPK----EKCSLFRPVDetekrcqvyQRRVVLTTSCGESliwSHTV---KFVIDVGLERR 364
Cdd:PRK11131 306 LNKL------NLRHTEILPLYARlsnsEQNRVFQSHS---------GRRIVLATNVAET---SLTVpgiKYVIDPGTARI 367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 365 QVYNPRIRANSLVLQPISQSQAEIRKQLLGSSPSGKLFCLYTEE-FASkdmRP-LKPAEMQEANLTSMVLFMKRVDIAGL 442
Cdd:PRK11131 368 SRYSYRTKVQRLPIEPISQASANQRKGRCGRVSEGICIRLYSEDdFLS---RPeFTDPEILRTNLASVILQMTALGLGDI 444
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 443 GRCDFMNRPAPESLMQALEDLDYLAALDNDGN-----LSEFGIIMSEFPLDPQLSKSILASCEFDCVDEMLTIAAMVTA- 516
Cdd:PRK11131 445 AAFPFVEAPDKRNIQDGVRLLEELGAITTDEQasaykLTPLGRQLAQLPVDPRLARMVLEAQKHGCVREVMIITSALSIq 524
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 517 -PScflHVPHGAEEAAVTCWKTFLHPEGDHFTLINVYNaY---QDTVLnSANEhcVEMWCHDCFLSCSALRMADVIRAEL 592
Cdd:PRK11131 525 dPR---ERPMDKQQASDEKHRRFADKESDFLAFVNLWN-YlqeQQKAL-SSNQ--FRRLCRTDYLNYLRVREWQDIYTQL 597
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 593 LEIIKRIELPY-AEPAfgskeNGLNIKKALLSGYFMQIA-RDVD-----GSGNylmlthkqvAQLHPLSSYSITKKMPEW 665
Cdd:PRK11131 598 RQVVKELGIPVnSEPA-----EYREIHTALLTGLLSHIGmKDAEkqeytGARN---------ARFSIFPGSGLFKKPPKW 663
|
650 660
....*....|....*....|...
gi 2214414571 666 VLFHQFSISENNYIRVASAVSPE 688
Cdd:PRK11131 664 VMVAELVETSRLWGRIAARIEPE 686
|
|
| SF2_C_RHA |
cd18791 |
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A ... |
241-405 |
2.78e-48 |
|
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family members are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350178 [Multi-domain] Cd Length: 171 Bit Score: 168.10 E-value: 2.78e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 241 HPVEVVYL-----------SGAQKDSFESVIRLIFEIHRSGEKGDVVVFLACEQDIEKTYELVcqEGSNLNPDVGDLVVI 309
Cdd:cd18791 1 FPVEVYYLedilellgissEKEDPDYVDAAVRLILQIHRTEEPGDILVFLPGQEEIERLCELL--REELLSPDLGKLLVL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 310 PLYPKEKCSLFRPVDEtekRCQVYQRRVVLTTSCGESLIWSHTVKFVIDVGLERRQVYNPRIRANSLVLQPISQSQAEIR 389
Cdd:cd18791 79 PLHSSLPPEEQQRVFE---PPPPGVRKVVLATNIAETSITIPGVVYVIDSGLVKEKVYDPRTGLSSLVTVWISKASAEQR 155
|
170
....*....|....*.
gi 2214414571 390 KQLLGSSPSGKLFCLY 405
Cdd:cd18791 156 AGRAGRTRPGKCYRLY 171
|
|
| HA2 |
pfam04408 |
Helicase associated domain (HA2); This presumed domain is about 90 amino acid residues in ... |
459-548 |
1.16e-24 |
|
Helicase associated domain (HA2); This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Pssm-ID: 461295 [Multi-domain] Cd Length: 104 Bit Score: 98.85 E-value: 1.16e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 459 ALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEMLTIAAMVTAPSCFLHVPHG---AEEAAVTCW 535
Cdd:pfam04408 1 ALELLYYLGALDEDGELTPLGRKMAELPLDPRLAKMLLAAAELGCLDEVLTIVAALSVRDPFVQPNFLdprSAAKAARRR 80
|
90 100
....*....|....*....|....
gi 2214414571 536 KTFLHPE-----------GDHFTL 548
Cdd:pfam04408 81 RRAADEKarakfarldleGDHLTL 104
|
|
| HA2 |
smart00847 |
Helicase associated domain (HA2) Add an annotation; This presumed domain is about 90 amino ... |
465-549 |
1.25e-22 |
|
Helicase associated domain (HA2) Add an annotation; This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Pssm-ID: 214852 [Multi-domain] Cd Length: 82 Bit Score: 92.33 E-value: 1.25e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 465 YLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEMLTIAAMVTAPSCFlhvPHGAEEAAVTCWKTFLHPEGD 544
Cdd:smart00847 1 ELGALDDDGRLTPLGRKMAELPLDPRLAKMLLAAAEFGCLDEILTIVAMLSVGDPR---PKEKREDADAARRRFADPESD 77
|
....*
gi 2214414571 545 HFTLI 549
Cdd:smart00847 78 HLTLL 82
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
56-191 |
5.84e-04 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 41.71 E-value: 5.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 56 LKEREELPIWKEKYSFMESLLQN-QVVVVSGDSKCGKSSQVPQWCAEYCLsiHYQHGGVICTQAHKQTAVQLALRVADEM 134
Cdd:smart00487 1 IEKFGFEPLRPYQKEAIEALLSGlRDVILAAPTGSGKTLAALLPALEALK--RGKGGRVLVLVPTRELAEQWAEELKKLG 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2214414571 135 DVNIGHEVGYvipFENCCTTETILR---------YCTDDMLQREMMSNPF-LGSYGVIILDDVHERS 191
Cdd:smart00487 79 PSLGLKVVGL---YGGDSKREQLRKlesgktdilVTTPGRLLDLLENDKLsLSNVDLVILDEAHRLL 142
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
40-91 |
4.36e-03 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 40.83 E-value: 4.36e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2214414571 40 LNPFDGLP-YSS---RYYKLlKEREELP-----IWKEKYSFMESLLQNQVVVVSGDSKCGK 91
Cdd:COG5022 106 VNPYRDLGiYTDdiiQSYSG-KNRLELEphvfaIAEEAYRNLLSEKENQTIIISGESGAGK 165
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| DEXHc_DHX32 |
cd17977 |
DEXH-box helicase domain of DEAH-box helicase 32; DEAH-box helicase 32 (DHX32) belongs to the ... |
62-237 |
1.41e-109 |
|
DEXH-box helicase domain of DEAH-box helicase 32; DEAH-box helicase 32 (DHX32) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350735 [Multi-domain] Cd Length: 176 Bit Score: 330.25 E-value: 1.41e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 62 LPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQWCAEYCLSIHYQHGGVICTQAHKQTAVQLALRVADEMDVNIGHE 141
Cdd:cd17977 1 LPVWEAKYEFMESLAHNQIVIVSGDAKTGKSSQIPQWCAEYCLSAHYQHGVVVCTQVHKQTAVWLALRVADEMDVNIGHE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 142 VGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIVNCSPLL 221
Cdd:cd17977 81 VGYVIPFENCCTNETILRYCTDDMLLREMMSDPLLESYGVIILDDAHERTVSTDVLLGLLKDVLLSRPELKLVIITCPHL 160
|
170
....*....|....*.
gi 2214414571 222 TSKLSSYYGDVPVIEV 237
Cdd:cd17977 161 SSKLLSYYGNVPLIEV 176
|
|
| DEXQc_DQX1 |
cd17986 |
DEXQ-box helicase domain of DEAQ-box RNA dependent ATPase 1; DEAQ-box RNA dependent ATPase 1 ... |
62-237 |
3.47e-68 |
|
DEXQ-box helicase domain of DEAQ-box RNA dependent ATPase 1; DEAQ-box RNA dependent ATPase 1 (DQX1) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350744 [Multi-domain] Cd Length: 177 Bit Score: 222.08 E-value: 3.47e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 62 LPIWKEKYSFMESLLQNQ-VVVVSGDSKCGKSSQVPQWCAEYCLSIHYQHGGVICTQAHKQTAVQLALRVADEMDVNIGH 140
Cdd:cd17986 1 LPIWAAKFTFLEQLESPSgIVLVSGEPGSGKSTQVPQWCAEFALSRGFQKGQVTVTQPHPLAARSLALRVADEMDLNLGH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 141 EVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIVNCSPL 220
Cdd:cd17986 81 EVGYSIPQEDCTGPNTILRFCWDRLLLQEMTSTPLLGAWGVVVLDEAQERSVASDSLLGLLKDVRLQRPELRVVVVTSPA 160
|
170
....*....|....*..
gi 2214414571 221 LTSKLSSYYGDVPVIEV 237
Cdd:cd17986 161 LEPKLRAFWGNPPVVHV 177
|
|
| DEXHc_RHA-like |
cd17917 |
DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) ... |
78-237 |
4.50e-61 |
|
DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438707 [Multi-domain] Cd Length: 159 Bit Score: 202.30 E-value: 4.50e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 78 NQVVVVSGDSKCGKSSQVPQWCAEYCLSIHyQHGGVICTQAHKQTAVQLALRVADEMDVNIGHEVGYVIPFENCCTTETI 157
Cdd:cd17917 1 NQVVVIVGETGSGKTTQVPQFLLEDGLAKG-GKGRIVCTQPRRIAAISVAERVAEERGEKLGEEVGYQIRFESKTSSKTR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 158 LRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIVNCSPLLTSKLSSYYGDVPVIEV 237
Cdd:cd17917 80 IKFCTDGILLRELLSDPLLSGYSHVILDEAHERSLDTDFLLGLLKDLLRKRPDLKVILMSATLDAEKFSSYFGGAPVIHI 159
|
|
| DEXHc_DHX15 |
cd17973 |
DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA ... |
51-237 |
1.48e-60 |
|
DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. DHX15 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438709 [Multi-domain] Cd Length: 187 Bit Score: 201.88 E-value: 1.48e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 51 RYYKLLKEREELPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQWCAEYCLSiHYQHGGVICTQAHKQTAVQLALRV 130
Cdd:cd17973 2 RYFEILEKRRELPVWEQKEDFLKLLKNNQILVLVGETGSGKTTQIPQFVLDDELP-HQPKKLVACTQPRRVAAMSVAQRV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 131 ADEMDVNIGHEVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPE 210
Cdd:cd17973 81 AEEMDVKLGEEVGYSIRFEDCSSAKTILKYMTDGMLLREAMSDPLLSRYSVIILDEAHERTLATDILMGLLKEVVRRRPD 160
|
170 180
....*....|....*....|....*..
gi 2214414571 211 LKLIVNCSPLLTSKLSSYYGDVPVIEV 237
Cdd:cd17973 161 LKLIVMSATLDAGKFQKYFDNAPLLKV 187
|
|
| HrpA |
COG1643 |
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]; |
73-695 |
1.88e-59 |
|
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 441249 [Multi-domain] Cd Length: 836 Bit Score: 215.72 E-value: 1.88e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 73 ESLLQNQVVVVSGDSKCGKSSQVPQWCAEyclSIHYQHGGVICTQ----AhkqtAVQLALRVADEMDVNIGHEVGYVIPF 148
Cdd:COG1643 21 AALRAHQVVVLAAPPGAGKTTQLPLALLE---LGWGAGGRIGMLEprrlA----ARAAAERMAEELGEPVGETVGYRVRF 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 149 ENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATD--------VLLGLlkdvllaRPELKLIVncspl 220
Cdd:COG1643 94 EDKVSAATRIEVVTEGILLRELQRDPELEGVDTVIFDEFHERSLNADlllallldLQPAL-------RPDLKLLV----- 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 221 lTS------KLSSYYGDVPVIEV--RNkHPVEVVYL--SGAQKDSFESVIRLIFEIHRSGEkGDVVVFLACEQDIEKTYE 290
Cdd:COG1643 162 -MSatldaeRFARLLGDAPVIESsgRT-YPVEVRYRplPADERDLEDAVADAVREALAEEP-GDILVFLPGEREIRRTAE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 291 LvcqegsnLNPDVG-DLVVIPLY----PKEKCSLFRPVDETekrcqvyQRRVVLTTSCGESliwSHTV---KFVIDVGLE 362
Cdd:COG1643 239 A-------LRGRLPpDTEILPLYgrlsAAEQDRAFAPAPHG-------RRRIVLATNIAET---SLTVpgiRYVIDSGLA 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 363 RRQVYNPRIRANSLVLQPISQSQAEIRKqllGS----SPsGKLFCLYTEE-FASkdMRPLKPAEMQEANLTSMVLFMKR- 436
Cdd:COG1643 302 RIPRYDPRSGVTRLPTERISQASANQRA---GRagrlAP-GICYRLWSEEdFAR--RPAFTDPEILRADLASLILELAAw 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 437 --VDIAGLgrcDFMNRPAPESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEMLTIAAMV 514
Cdd:COG1643 376 glGDPEDL---PFLDPPPARAIADARALLQELGALDADGRLTPLGRALARLPLDPRLARMLLAAAELGCLREAAILAALL 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 515 TAPscflHVPHGAeeaavtcwktflhPEGDHFTLINVYNAYQDTVLNsanehcvemwchdcFLSCSALRmadviraELLE 594
Cdd:COG1643 453 SER----DPRRGA-------------AGSDLLARLNLWRRLREQQRE--------------FLSYLRLR-------EWRD 494
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 595 IIKRIELPYAEPAFGSKENGLNIKKALLSGYFMQIARDVDGSGNYLmLTHKQVAQLHPLSsySITKKmpEWVLfhqfsIS 674
Cdd:COG1643 495 LARQLRRLLGEGANEEPADYEAIGLLLALAYPDRIARRRGEGGRYL-LARGRGAALFPGS--PLAKK--EWLV-----AA 564
|
650 660
....*....|....*....|....*..
gi 2214414571 675 E------NNYIRVASAVSPELFMQLVP 695
Cdd:COG1643 565 ElvggaaEARIRLAAPIDPEWLEELAA 591
|
|
| PRK11131 |
PRK11131 |
ATP-dependent RNA helicase HrpA; Provisional |
60-688 |
2.59e-50 |
|
ATP-dependent RNA helicase HrpA; Provisional
Pssm-ID: 182986 [Multi-domain] Cd Length: 1294 Bit Score: 191.04 E-value: 2.59e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 60 EELPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQWCAEYCLSIHyqhgGVIC-TQAHKQTAVQLALRVADEMDVNI 138
Cdd:PRK11131 71 ENLPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICLELGRGVK----GLIGhTQPRRLAARTVANRIAEELETEL 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 139 GHEVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIVNCS 218
Cdd:PRK11131 147 GGCVGYKVRFNDQVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFILGYLKELLPRRPDLKVIITSA 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 219 PLLTSKLSSYYGDVPVIEVRNK-HPVEVVY--LSGAQKDSFESVIRLIF----EIHRSGeKGDVVVFLACEQDIEKTYEL 291
Cdd:PRK11131 227 TIDPERFSRHFNNAPIIEVSGRtYPVEVRYrpIVEEADDTERDQLQAIFdavdELGREG-PGDILIFMSGEREIRDTADA 305
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 292 VCQEgsnlnpDVGDLVVIPLYPK----EKCSLFRPVDetekrcqvyQRRVVLTTSCGESliwSHTV---KFVIDVGLERR 364
Cdd:PRK11131 306 LNKL------NLRHTEILPLYARlsnsEQNRVFQSHS---------GRRIVLATNVAET---SLTVpgiKYVIDPGTARI 367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 365 QVYNPRIRANSLVLQPISQSQAEIRKQLLGSSPSGKLFCLYTEE-FASkdmRP-LKPAEMQEANLTSMVLFMKRVDIAGL 442
Cdd:PRK11131 368 SRYSYRTKVQRLPIEPISQASANQRKGRCGRVSEGICIRLYSEDdFLS---RPeFTDPEILRTNLASVILQMTALGLGDI 444
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 443 GRCDFMNRPAPESLMQALEDLDYLAALDNDGN-----LSEFGIIMSEFPLDPQLSKSILASCEFDCVDEMLTIAAMVTA- 516
Cdd:PRK11131 445 AAFPFVEAPDKRNIQDGVRLLEELGAITTDEQasaykLTPLGRQLAQLPVDPRLARMVLEAQKHGCVREVMIITSALSIq 524
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 517 -PScflHVPHGAEEAAVTCWKTFLHPEGDHFTLINVYNaY---QDTVLnSANEhcVEMWCHDCFLSCSALRMADVIRAEL 592
Cdd:PRK11131 525 dPR---ERPMDKQQASDEKHRRFADKESDFLAFVNLWN-YlqeQQKAL-SSNQ--FRRLCRTDYLNYLRVREWQDIYTQL 597
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 593 LEIIKRIELPY-AEPAfgskeNGLNIKKALLSGYFMQIA-RDVD-----GSGNylmlthkqvAQLHPLSSYSITKKMPEW 665
Cdd:PRK11131 598 RQVVKELGIPVnSEPA-----EYREIHTALLTGLLSHIGmKDAEkqeytGARN---------ARFSIFPGSGLFKKPPKW 663
|
650 660
....*....|....*....|...
gi 2214414571 666 VLFHQFSISENNYIRVASAVSPE 688
Cdd:PRK11131 664 VMVAELVETSRLWGRIAARIEPE 686
|
|
| SF2_C_RHA |
cd18791 |
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A ... |
241-405 |
2.78e-48 |
|
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family members are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350178 [Multi-domain] Cd Length: 171 Bit Score: 168.10 E-value: 2.78e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 241 HPVEVVYL-----------SGAQKDSFESVIRLIFEIHRSGEKGDVVVFLACEQDIEKTYELVcqEGSNLNPDVGDLVVI 309
Cdd:cd18791 1 FPVEVYYLedilellgissEKEDPDYVDAAVRLILQIHRTEEPGDILVFLPGQEEIERLCELL--REELLSPDLGKLLVL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 310 PLYPKEKCSLFRPVDEtekRCQVYQRRVVLTTSCGESLIWSHTVKFVIDVGLERRQVYNPRIRANSLVLQPISQSQAEIR 389
Cdd:cd18791 79 PLHSSLPPEEQQRVFE---PPPPGVRKVVLATNIAETSITIPGVVYVIDSGLVKEKVYDPRTGLSSLVTVWISKASAEQR 155
|
170
....*....|....*.
gi 2214414571 390 KQLLGSSPSGKLFCLY 405
Cdd:cd18791 156 AGRAGRTRPGKCYRLY 171
|
|
| DEXHc_DHX8 |
cd17971 |
DEXH-box helicase domain of DEAH-box helicase 8; DEAH-box helicase 8 (DHX8 ,also known as ... |
58-237 |
1.33e-45 |
|
DEXH-box helicase domain of DEAH-box helicase 8; DEAH-box helicase 8 (DHX8 ,also known as pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22) acts late in the splicing of pre-mRNA and mediates the release of the spliced mRNA from spliceosomes. DHX8 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350729 [Multi-domain] Cd Length: 179 Bit Score: 160.73 E-value: 1.33e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 58 EREELPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQWCAEYCLSihyQHGGVICTQAHKQTAVQLALRVADEMDVN 137
Cdd:cd17971 2 QRESLPIYKLKEQLIQAVHDNQILVVIGETGSGKTTQITQYLAEAGYT---SRGKIGCTQPRRVAAMSVAKRVAEEFGCC 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 138 IGHEVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIVNC 217
Cdd:cd17971 79 LGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLSQYSVIMLDEAHERTIHTDVLFGLLKKTVQKRPDLKLIVTS 158
|
170 180
....*....|....*....|
gi 2214414571 218 SPLLTSKLSSYYGDVPVIEV 237
Cdd:cd17971 159 ATLDAVKFSQYFYEAPIFTI 178
|
|
| DEXHc_DHX16 |
cd17974 |
DEXH-box helicase domain of DEAH-box helicase 16; DEAH-box helicase 16 (DHX16) is probably ... |
62-237 |
1.51e-44 |
|
DEXH-box helicase domain of DEAH-box helicase 16; DEAH-box helicase 16 (DHX16) is probably involved in pre-mRNA splicing. DHX16 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350732 [Multi-domain] Cd Length: 174 Bit Score: 157.66 E-value: 1.51e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 62 LPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQWCAE--YClsihyQHGGVI-CTQAHKQTAVQLALRVADEMDVNI 138
Cdd:cd17974 1 LPVYPYRDDLLAAVKEHQVLIIVGETGSGKTTQIPQYLHEagYT-----KGGGKIgCTQPRRVAAMSVAARVAEEMGVKL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 139 GHEVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIVNCS 218
Cdd:cd17974 76 GNEVGYSIRFEDCTSEKTVLKYMTDGMLLREFLTEPDLASYSVMIIDEAHERTLHTDILFGLVKDIARFRPDLKLLISSA 155
|
170
....*....|....*....
gi 2214414571 219 PLLTSKLSSYYGDVPVIEV 237
Cdd:cd17974 156 TMDAEKFSAFFDDAPIFRI 174
|
|
| DEXHc_DHX38 |
cd17983 |
DEXH-box helicase domain of DEAH-box helicase 38; DEAH-box helicase 38 (DHX38, also known as ... |
62-237 |
3.17e-39 |
|
DEXH-box helicase domain of DEAH-box helicase 38; DEAH-box helicase 38 (DHX38, also known as PRP16) is involved in pre-mRNA splicing. DHX38 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350741 [Multi-domain] Cd Length: 173 Bit Score: 142.99 E-value: 3.17e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 62 LPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQwcaeYCLSIHYQHGGVI-CTQAHKQTAVQLALRVADEMDVNIGH 140
Cdd:cd17983 1 LPIFAVRQELLNVIRDNNVVIVVGETGSGKTTQLTQ----YLHEDGYTDYGMIgCTQPRRVAAMSVAKRVSEEMGVELGE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 141 EVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIVNCSPL 220
Cdd:cd17983 77 EVGYAIRFEDCTSENTVIKYMTDGILLRESLRDPDLDKYSAIIMDEAHERSLNTDVLFGLLREVVARRRDLKLIVTSATM 156
|
170
....*....|....*..
gi 2214414571 221 LTSKLSSYYGDVPVIEV 237
Cdd:cd17983 157 DADKFADFFGNVPIFTI 173
|
|
| DEXHc_DHX35 |
cd17980 |
DEXH-box helicase domain of DEAH-box helicase 35; DHX35 plays a role in colorectal cancers and ... |
62-229 |
7.03e-39 |
|
DEXH-box helicase domain of DEAH-box helicase 35; DHX35 plays a role in colorectal cancers and seems to be associated with risk to thyroid cancers. It also has been shown to positively regulate poxviruses, such as Myxoma virus. DEAH-box helicase 35 (DHX35) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350738 [Multi-domain] Cd Length: 185 Bit Score: 142.22 E-value: 7.03e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 62 LPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQWCAEyclsIHYQHGG--VICTQAHKQTAVQLALRVADEMDVNIG 139
Cdd:cd17980 1 LPVFKLRNHILYLVENYQTIVIVGETGCGKSTQIPQYLAE----AGWTAGGrvVGCTQPRRVAAVTVAGRVAEEMGAVLG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 140 HEVGYVIPFENCCTT-ETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIVNCS 218
Cdd:cd17980 77 HEVGYCIRFDDCTDPqATRIKFLTDGMLVREMMLDPLLTKYSVIMLDEAHERTLYTDILIGLLKKIQKKRGDLRLIVASA 156
|
170
....*....|.
gi 2214414571 219 PLLTSKLSSYY 229
Cdd:cd17980 157 TLDAEKFRDFF 167
|
|
| DEXHc_DHX33 |
cd17978 |
DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA ... |
62-235 |
1.05e-38 |
|
DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA polymerase I transcription of the 47S precursor rRNA. DHX33 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438710 [Multi-domain] Cd Length: 178 Bit Score: 141.34 E-value: 1.05e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 62 LPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQwcaeYCLSIHYQHGGVI-CTQAHKQTAVQLALRVADEMDVNIGH 140
Cdd:cd17978 1 LPIYSARKRLLEELRKHDTVIIIGETGSGKTTQIPQ----YLYEAGFARGGMIgITQPRRVAAVSVAKRVAEEMGVELGQ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 141 EVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLAR-----PELKLIV 215
Cdd:cd17978 77 LVGYSVRFDDVTSEETRIKYMTDGMLLREAIGDPLLSKYSVIILDEAHERTVHTDVLFGLVKSAQRRRkeqklSPLKVII 156
|
170 180
....*....|....*....|
gi 2214414571 216 NCSPLLTSKLSSYYGDVPVI 235
Cdd:cd17978 157 MSATLDADLFSEYFNGAPVL 176
|
|
| DEXHc_DHX40 |
cd17984 |
DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the ... |
62-237 |
6.65e-36 |
|
DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350742 [Multi-domain] Cd Length: 178 Bit Score: 133.44 E-value: 6.65e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 62 LPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQWCAEYCLSihyQHGGVICTQAHKQTAVQLALRVADEMDVNIGHE 141
Cdd:cd17984 1 LPIQKQRKKLVQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFS---QHGMIGVTQPRRVAAISVAQRVAEEMKCTLGSK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 142 VGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDV-----LLGLLKDVLLARPELKLIVN 216
Cdd:cd17984 78 VGYQVRFDDCSSKETAIKYMTDGCLLRHILADPNLTKYSVIILDEAHERSLTTDIlfgllKKLFQEKSPNRKEHLKVVVM 157
|
170 180
....*....|....*....|.
gi 2214414571 217 CSPLLTSKLSSYYGDVPVIEV 237
Cdd:cd17984 158 SATLELAKLSAFFGNCPVFDI 178
|
|
| DEXHc_DHX34 |
cd17979 |
DEXH-box helicase domain of DEAH-box helicase 34; DEAH-box helicase 34 (DHX34) plays a role in ... |
62-237 |
1.31e-34 |
|
DEXH-box helicase domain of DEAH-box helicase 34; DEAH-box helicase 34 (DHX34) plays a role in the nonsense-mediated decay (NMD), a surveillance mechanism that degrades aberrant mRNAs. DHX34 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350737 [Multi-domain] Cd Length: 170 Bit Score: 129.48 E-value: 1.31e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 62 LPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQwcaeYCLSIHYQHggVICTQAHKQTAVQLALRVADEMDVNIGHE 141
Cdd:cd17979 1 LPIAQYREKIIELLKTHQVVIVAGDTGCGKSTQVPQ----YLLAAGFRH--IACTQPRRIACISLAKRVAFESLNQYGSK 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 142 VGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIVNCSPLL 221
Cdd:cd17979 75 VAYQIRFERTRTLATKLLFLTEGLLLRQIQRDASLPQYNVLILDEVHERHLHGDFLLGVLRCLLRLRPDLKLILMSATIN 154
|
170
....*....|....*.
gi 2214414571 222 TSKLSSYYGDVPVIEV 237
Cdd:cd17979 155 IELFSGYFEGAPVVQV 170
|
|
| DEXHc_DHX57 |
cd17985 |
DEXH-box helicase domain of DEAH-box helicase 57; DEAH-box helicase 57 (DHX57) belongs to the ... |
62-237 |
5.41e-32 |
|
DEXH-box helicase domain of DEAH-box helicase 57; DEAH-box helicase 57 (DHX57) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350743 [Multi-domain] Cd Length: 177 Bit Score: 122.26 E-value: 5.41e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 62 LPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQWCAEYCL-SIHYQHGGVICTQAHKQTAVQLALRVADEMDVNIGH 140
Cdd:cd17985 1 LPAWQERETILELLEKHQVLVISGMTGCGKTTQIPQFILDNSLqGPPLPVANIICTQPRRISAISVAERVAQERAERVGQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 141 EVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIVNCSPL 220
Cdd:cd17985 81 SVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDPTLQGVTHVIVDEVHERTEESDFLLLVLKDLMVQRPDLKVILMSATL 160
|
170
....*....|....*..
gi 2214414571 221 LTSKLSSYYGDVPVIEV 237
Cdd:cd17985 161 NAELFSDYFNSCPVIHI 177
|
|
| DEXHc_HrpA |
cd17989 |
DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA ... |
62-237 |
1.10e-29 |
|
DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350747 [Multi-domain] Cd Length: 173 Bit Score: 115.63 E-value: 1.10e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 62 LPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQWCAEYCLSIHyqhgGVIC-TQAHKQTAVQLALRVADEMDVNIGH 140
Cdd:cd17989 1 LPVSQKRDEIAKAIAENQVVIIAGETGSGKTTQLPKICLELGRGIR----GLIGhTQPRRLAARSVAERIAEELKTELGG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 141 EVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIVNCSPL 220
Cdd:cd17989 77 AVGYKVRFTDQTSDETCVKLMTDGILLAETQTDRYLRAYDTIIIDEAHERSLNIDFLLGYLKQLLPRRPDLKVIITSATI 156
|
170
....*....|....*..
gi 2214414571 221 LTSKLSSYYGDVPVIEV 237
Cdd:cd17989 157 DAERFSRHFNNAPIIEV 173
|
|
| DEXHc_DHX37 |
cd17982 |
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the ... |
62-196 |
1.27e-28 |
|
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the human nervous system and has been linked to schizophrenia. It also negatively regulates poxviruses such as Myxoma virus. DEAH-box helicase 37 (DHX37) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350740 [Multi-domain] Cd Length: 191 Bit Score: 113.22 E-value: 1.27e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 62 LPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQ--WCAEYCLSIHYQHGGVICTQAHKQTAVQLALRVADEMDVnIG 139
Cdd:cd17982 1 LPILAEEQEIMEAINENPVVIICGETGSGKTTQVPQflYEAGFGSPESDNPGMIGITQPRRVAAVSMAKRVAEELNV-FG 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 2214414571 140 HEVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDV 196
Cdd:cd17982 80 KEVSYQIRYDSTVSENTKIKFMTDGVLLKEIQTDFLLRKYSVIIIDEAHERSVNTDI 136
|
|
| DEXHc_DHX30 |
cd17976 |
DEXH-box helicase domain of DEAH-box helicase 30; DEAH-box helicase 30 (DHX30) plays an ... |
62-237 |
2.32e-28 |
|
DEXH-box helicase domain of DEAH-box helicase 30; DEAH-box helicase 30 (DHX30) plays an important role in the assembly of the mitochondrial large ribosomal subunit. DHX30 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350734 [Multi-domain] Cd Length: 178 Bit Score: 112.19 E-value: 2.32e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 62 LPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQWCAE-YCLSIHYQHGGVICTQAHKQTAVQLALRVADEMDVNIGH 140
Cdd:cd17976 1 LPVDSHKESILSAIEQNPVVVISGDTGCGKTTRIPQFILEdYVLRGRGARCNVVITQPRRISAVSVAQRVAHELGPNLRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 141 EVGYVIPFENCCTTET-ILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIVNCSP 219
Cdd:cd17976 81 NVGYQVRLESRPPPRGgALLFCTVGVLLKKLQSNPRLEGVSHVIVDEVHERDVNTDFLLILLKGVLQLNPELRVVLMSAT 160
|
170
....*....|....*...
gi 2214414571 220 LLTSKLSSYYGDVPVIEV 237
Cdd:cd17976 161 GDNQRLSRYFGGCPVVRV 178
|
|
| DEXHc_DHX36 |
cd17981 |
DEXH-box helicase domain of DEAH-box helicase 36; DEAH-box helicase 36 (DHX36, also known as ... |
62-237 |
1.17e-26 |
|
DEXH-box helicase domain of DEAH-box helicase 36; DEAH-box helicase 36 (DHX36, also known as G4-resolvase 1 or G4R1, MLE-like protein 1 and RNA helicase associated with AU-rich element or RHAU) unwinds a G4-quadruplex in human telomerase RNA. DHX36 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350739 [Multi-domain] Cd Length: 180 Bit Score: 107.24 E-value: 1.17e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 62 LPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQwcaeYCLSIHYQHGG-----VICTQAHKQTAVQLALRVADEM-- 134
Cdd:cd17981 1 LPSYGMKQEIINMIDNNQVTVISGETGCGKTTQVTQ----FILDDAIERGKgsscrIVCTQPRRISAISVAERVAAERae 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 135 DVNIGHEVGYVIPFENCCTTE--TILrYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELK 212
Cdd:cd17981 77 SCGLGNSTGYQIRLESRKPRKqgSIL-YCTTGIVLQWLQSDPHLSNVSHLVLDEIHERNLQSDVLMGIVKDLLPFRSDLK 155
|
170 180
....*....|....*....|....*
gi 2214414571 213 LIVNCSPLLTSKLSSYYGDVPVIEV 237
Cdd:cd17981 156 VILMSATLNAEKFSDYFNNCPMIHI 180
|
|
| DEXHc_DHX29 |
cd17975 |
DEXH-box helicase domain of DEAH-box helicase 29; DEAH-box helicase 29 (DHX29) is a part of ... |
62-237 |
3.85e-26 |
|
DEXH-box helicase domain of DEAH-box helicase 29; DEAH-box helicase 29 (DHX29) is a part of the 43S pre-initiation complex involved in translation initiation of mRNAs with structured 5'-UTRs. DHX29 is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350733 [Multi-domain] Cd Length: 183 Bit Score: 105.77 E-value: 3.85e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 62 LPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQWCAEYCLSIHYQHG--GVICTQAHKQTAVQLALRVADEMDVNIG 139
Cdd:cd17975 1 LPVFKHRESILETLKRHRVVVVAGETGSGKSTQVPQFLLEDLLLNGGTAQkcNIVCTQPRRISAMSLATRVCEELGCESG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 140 -----HEVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLI 214
Cdd:cd17975 81 pggknSLCGYQIRMESRTGEATRLLYCTTGVLLRKLQEDGLLSSISHIIVDEVHERSVQSDFLLIILKEILHKRSDLHLI 160
|
170 180
....*....|....*....|...
gi 2214414571 215 VNCSPLLTSKLSSYYGDVPVIEV 237
Cdd:cd17975 161 LMSATVDCEKFSSYFTHCPILRI 183
|
|
| DEXHc_YTHDC2 |
cd17987 |
DEXH-box helicase domain of YTH domain containing 2; YTH domain containing 2 (YTHDC2) ... |
62-237 |
7.53e-26 |
|
DEXH-box helicase domain of YTH domain containing 2; YTH domain containing 2 (YTHDC2) regulates mRNA translation and stability via binding to N6-methyladenosine, a modified RNA nucleotide enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. YTHDC2 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350745 [Multi-domain] Cd Length: 176 Bit Score: 104.91 E-value: 7.53e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 62 LPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQWCAEYClsihYQHGG---VICTQAHKQTAVQLALRVADEMDVNI 138
Cdd:cd17987 1 LPVFEKQEQIVRIIKENKVVLIVGETGSGKTTQIPQFLLDDC----YANGIpcrIFCTQPRRLAAIAVAERVAAERGEKI 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 139 GHEVGYVIPFENCCTTETILRYCTDDMLQREMMS-NPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIVNC 217
Cdd:cd17987 77 GQTVGYQIRLESRVSPKTLLTFCTNGVLLRTLMAgDSALSTVTHVIVDEVHERDRFSDFLLTKLRDILQKHPNLKLILSS 156
|
170 180
....*....|....*....|
gi 2214414571 218 SPLLTSKLSSYYGDVPVIEV 237
Cdd:cd17987 157 AALDVNLFIRYFGSCPVIYI 176
|
|
| DEXHc_DHX9 |
cd17972 |
DEXH-box helicase domain of DEAH-box helicase 9; DEAH-box helicase 9 (DHX9, also known as ... |
9-237 |
5.46e-25 |
|
DEXH-box helicase domain of DEAH-box helicase 9; DEAH-box helicase 9 (DHX9, also known as ATP-dependent RNA helicase A or RHA and leukophysin or LKP) plays an important role in many cellular processes, including regulation of DNA replication, transcription, translation, microRNA biogenesis, RNA processing and transport, and maintenance of genomic stability. DHX9 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350730 [Multi-domain] Cd Length: 234 Bit Score: 104.15 E-value: 5.46e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 9 PNASPEKRYFPESldSSDGDEEGVLAC--EDLELNPFDGLPY----SSRYYKLLKEREELPIWKEKYSFMESLLQNQVVV 82
Cdd:cd17972 2 PWSPPQSNWNPWT--SSNIDEGPLAFAtpEQISMDLKNELMYqreqDHNLQQILQERELLPVKKFREEILEAISNNPVVI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 83 VSGDSKCGKSSQVPQWCA-EYCLSIHYQHGGVICTQAHKQTAVQLALRVADEMDVNIGHEVGYVIPFENCCTTE--TILr 159
Cdd:cd17972 80 IRGATGCGKTTQVPQYILdDFIQNDRAAECNIVVTQPRRISAVSVAERVAFERGEEVGKSCGYSVRFESVLPRPhaSIL- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 160 YCTDDMLQREMMSnpflGSYGV--IILDDVHERSLATDVLLGLLKDVLLARPELKLIVNCSPLLTSKLSSYYGDVPVIEV 237
Cdd:cd17972 159 FCTVGVLLRKLEA----GIRGIshVIVDEIHERDINTDFLLVVLRDVVQAYPDLRVILMSATIDTSMFCEYFFNCPVIEV 234
|
|
| PRK11664 |
PRK11664 |
ATP-dependent RNA helicase HrpB; Provisional |
127-516 |
7.07e-25 |
|
ATP-dependent RNA helicase HrpB; Provisional
Pssm-ID: 236950 [Multi-domain] Cd Length: 812 Bit Score: 110.78 E-value: 7.07e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 127 ALRVADEMDVNIGHEVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLL 206
Cdd:PRK11664 65 AQRLAEQLGEKPGETVGYRMRAESKVGPNTRLEVVTEGILTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVQQ 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 207 A-RPELKLIVNCSPLLTSKLSSYYGDVPVIEVRNK-HPVEVVYLSGAQKDSF-ESVIRLIFEIHRSgEKGDVVVFLACEQ 283
Cdd:PRK11664 145 GlRDDLKLLIMSATLDNDRLQQLLPDAPVIVSEGRsFPVERRYQPLPAHQRFdEAVARATAELLRQ-ESGSLLLFLPGVG 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 284 DIEKTYELvcqegsnLNPDVGDLVVI-PLY----PKEKCSLFRPVDetekrcqVYQRRVVLTTSCGESliwSHT---VKF 355
Cdd:PRK11664 224 EIQRVQEQ-------LASRVASDVLLcPLYgalsLAEQQKAILPAP-------AGRRKVVLATNIAET---SLTiegIRL 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 356 VIDVGLERRQVYNPRIRANSLVLQPISQSQAEIRKQLLGSSPSGKLFCLYTEEFASKdmRPLKP-AEMQEANLTSMVLfm 434
Cdd:PRK11664 287 VVDSGLERVARFDPKTGLTRLVTQRISQASMTQRAGRAGRLEPGICLHLYSKEQAER--AAAQSePEILHSDLSGLLL-- 362
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 435 krvDIAGLGRCD-----FMNRPAPESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDcvDEMLT 509
Cdd:PRK11664 363 ---ELLQWGCHDpaqlsWLDQPPAAALAAAKRLLQQLGALDGQGRLTARGRKMAALGNDPRLAAMLVAAKEDD--EAALA 437
|
....*..
gi 2214414571 510 IAAMVTA 516
Cdd:PRK11664 438 TAAKLAA 444
|
|
| HA2 |
pfam04408 |
Helicase associated domain (HA2); This presumed domain is about 90 amino acid residues in ... |
459-548 |
1.16e-24 |
|
Helicase associated domain (HA2); This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Pssm-ID: 461295 [Multi-domain] Cd Length: 104 Bit Score: 98.85 E-value: 1.16e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 459 ALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEMLTIAAMVTAPSCFLHVPHG---AEEAAVTCW 535
Cdd:pfam04408 1 ALELLYYLGALDEDGELTPLGRKMAELPLDPRLAKMLLAAAELGCLDEVLTIVAALSVRDPFVQPNFLdprSAAKAARRR 80
|
90 100
....*....|....*....|....
gi 2214414571 536 KTFLHPE-----------GDHFTL 548
Cdd:pfam04408 81 RRAADEKarakfarldleGDHLTL 104
|
|
| HA2 |
smart00847 |
Helicase associated domain (HA2) Add an annotation; This presumed domain is about 90 amino ... |
465-549 |
1.25e-22 |
|
Helicase associated domain (HA2) Add an annotation; This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Pssm-ID: 214852 [Multi-domain] Cd Length: 82 Bit Score: 92.33 E-value: 1.25e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 465 YLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEMLTIAAMVTAPSCFlhvPHGAEEAAVTCWKTFLHPEGD 544
Cdd:smart00847 1 ELGALDDDGRLTPLGRKMAELPLDPRLAKMLLAAAEFGCLDEILTIVAMLSVGDPR---PKEKREDADAARRRFADPESD 77
|
....*
gi 2214414571 545 HFTLI 549
Cdd:smart00847 78 HLTLL 82
|
|
| OB_NTP_bind |
pfam07717 |
Oligonucleotide/oligosaccharide-binding (OB)-fold; This family is found towards the C-terminus ... |
617-697 |
1.58e-21 |
|
Oligonucleotide/oligosaccharide-binding (OB)-fold; This family is found towards the C-terminus of the DEAD-box helicases (pfam00270). In these helicases it is apparently always found in association with pfam04408. There do seem to be a couple of instances where it occurs by itself -. The structure PDB:3i4u adopts an OB-fold. helicases (pfam00270). In these helicases it is apparently always found in association with pfam04408. This C-terminal domain of the yeast helicase contains an oligonucleotide/oligosaccharide-binding (OB)-fold which seems to be placed at the entrance of the putative nucleic acid cavity. It also constitutes the binding site for the G-patch-containing domain of Pfa1p. When found on DEAH/RHA helicases, this domain is central to the regulation of the helicase activity through its binding of both RNA and G-patch domain proteins.
Pssm-ID: 400182 [Multi-domain] Cd Length: 82 Bit Score: 89.23 E-value: 1.58e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 617 IKKALLSGYFMQIARDVDGSGNYLMLTHKQVAQLHPLSSY-SITKKMPEWVLFHQFSISENNYIRVASAVSPELFMQLVP 695
Cdd:pfam07717 1 LRAALAAGLYPNVARRDPKGKGYTTLSDNQRVFIHPSSVLfNEKTFPPEWVVYQELVETTKVYIRTVTAISPEWLLLFAP 80
|
..
gi 2214414571 696 QY 697
Cdd:pfam07717 81 HI 82
|
|
| DEXHc_TDRD9 |
cd17988 |
DEXH-box helicase domain of tudor domain containing 9; Tudor domain containing 9 (TDRD9, also ... |
62-195 |
2.46e-18 |
|
DEXH-box helicase domain of tudor domain containing 9; Tudor domain containing 9 (TDRD9, also known as HIG-1or NET54 or C14orf75) is a part of the nuclear PIWI-interacting RNA (piRNA) pathway essential for transposon silencing and male fertility TDRD9 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350746 [Multi-domain] Cd Length: 180 Bit Score: 83.32 E-value: 2.46e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 62 LPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQwcaeYCLSIHYQHG---GVICTQAHKQTAVQLALRVADEMDVNI 138
Cdd:cd17988 1 LPIYAKREEILSLIEANSVVIIKGATGCGKTTQLPQ----FILDHYYKRGkycNIVVTQPRRIAAISIARRVSQEREWTL 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 2214414571 139 GHEVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATD 195
Cdd:cd17988 77 GSLVGYQVGLERPASEETRLIYCTTGVLLQKLINNKTLTEYTHIILDEVHERDQELD 133
|
|
| DEXHc_HrpB |
cd17990 |
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA ... |
73-237 |
3.51e-18 |
|
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpB belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438711 [Multi-domain] Cd Length: 174 Bit Score: 82.76 E-value: 3.51e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 73 ESLLQNQVVVVSGDSKCGKSSQVP----QWCAEyclsihyQHGGVICTQAHKQTAVQLALRVADEMDVNIGHEVGYVIPF 148
Cdd:cd17990 12 AALDAGGQVVLEAPPGAGKTTRVPlallAELWI-------AGGKIIVLEPRRVAARAAARRLATLLGEAPGETVGYRVRG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 149 ENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLA-RPELKLIVNCSPLLTSKLSS 227
Cdd:cd17990 85 ESRVGRRTRVEVVTEGVLLRRLQRDPELSGVGAVILDEFHERSLDADLALALLLEVQQLlRDDLRLLAMSATLDGDGLAA 164
|
170
....*....|
gi 2214414571 228 YYGDVPVIEV 237
Cdd:cd17990 165 LLPEAPVVES 174
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
56-191 |
5.84e-04 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 41.71 E-value: 5.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214414571 56 LKEREELPIWKEKYSFMESLLQN-QVVVVSGDSKCGKSSQVPQWCAEYCLsiHYQHGGVICTQAHKQTAVQLALRVADEM 134
Cdd:smart00487 1 IEKFGFEPLRPYQKEAIEALLSGlRDVILAAPTGSGKTLAALLPALEALK--RGKGGRVLVLVPTRELAEQWAEELKKLG 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2214414571 135 DVNIGHEVGYvipFENCCTTETILR---------YCTDDMLQREMMSNPF-LGSYGVIILDDVHERS 191
Cdd:smart00487 79 PSLGLKVVGL---YGGDSKREQLRKlesgktdilVTTPGRLLDLLENDKLsLSNVDLVILDEAHRLL 142
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
40-91 |
4.36e-03 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 40.83 E-value: 4.36e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2214414571 40 LNPFDGLP-YSS---RYYKLlKEREELP-----IWKEKYSFMESLLQNQVVVVSGDSKCGK 91
Cdd:COG5022 106 VNPYRDLGiYTDdiiQSYSG-KNRLELEphvfaIAEEAYRNLLSEKENQTIIISGESGAGK 165
|
|
| |
