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Conserved domains on  [gi|18423709|ref|NP_568820|]
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SWAP (Suppressor-of-White-APricot)/surp domain-containing protein [Arabidopsis thaliana]

Protein Classification

DRY_EERY and SWAP domain-containing protein( domain architecture ID 10560971)

DRY_EERY and SWAP domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DRY_EERY pfam09750
Alternative splicing regulator; This entry represents the conserved N-terminal region of SWAP ...
 3-113 1.84e-25

Alternative splicing regulator; This entry represents the conserved N-terminal region of SWAP (suppressor-of-white-apricot protein) proteins. This region contains two highly conserved motifs, viz: DRY and EERY, which appear to be the sites for alternative splicing of exons 2 and 3 of the SWAP mRNA. These proteins are thus thought to be involved in auto-regulation of pre-mRNA splicing. Most family members are associated with two Surp domains pfam01805 and an Arginine- serine-rich binding region towards the C-terminus.


:

Pssm-ID: 462881  Cd Length: 129  Bit Score: 102.39  E-value: 1.84e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423709     3 LEIVGRHALFFDDDSMATFVNSPTALVDWN---SLFIDRYDVRHLLS----SPPPPRIKRRRPNSNDADLESELDHERYL 75
Cdd:pfam09750   1 LQVFGRRCKLFRDDAIAAAAESGKHLVPWQgdpDLLIDRFDVRALLDdipeYEAGRSARLSELTSEEEEEERECNYERYR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 18423709    76 DLPSESPSPSDDDEH-----------DMNEDSANTNADGYRAVSFSYGS 113
Cdd:pfam09750  81 DLIKNEFEGVSEEEElkriyqeeqfgAKRLSAAKKSSGSYAAIGFSYDD 129
SWAP smart00648
Suppressor-of-White-APricot splicing regulator; domain present in regulators which are ...
 151-201 6.47e-14

Suppressor-of-White-APricot splicing regulator; domain present in regulators which are responsible for pre-mRNA splicing processes


:

Pssm-ID: 197818 [Multi-domain]  Cd Length: 54  Bit Score: 66.84  E-value: 6.47e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 18423709    151 HQIITRTSSFVSKHGGQSEIVLRVKQGDNPTFGFLMPDHHLHLYFRFLVDH 201
Cdd:smart00648   1 LDIIDKTAQFVARNGPEFEAKLMERERNNPQFDFLKPNDPYHAYYRKKLAE 51
SWAP smart00648
Suppressor-of-White-APricot splicing regulator; domain present in regulators which are ...
 336-389 3.12e-13

Suppressor-of-White-APricot splicing regulator; domain present in regulators which are responsible for pre-mRNA splicing processes


:

Pssm-ID: 197818 [Multi-domain]  Cd Length: 54  Bit Score: 64.92  E-value: 3.12e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 18423709    336 KRVIDKIVDFIQKNGKELEATLVAQDVKYGMFPFLRPSSLYHAYYRKVLQEAEE 389
Cdd:smart00648   1 LDIIDKTAQFVARNGPEFEAKLMERERNNPQFDFLKPNDPYHAYYRKKLAEYRQ 54
 
Name Accession Description Interval E-value
DRY_EERY pfam09750
Alternative splicing regulator; This entry represents the conserved N-terminal region of SWAP ...
 3-113 1.84e-25

Alternative splicing regulator; This entry represents the conserved N-terminal region of SWAP (suppressor-of-white-apricot protein) proteins. This region contains two highly conserved motifs, viz: DRY and EERY, which appear to be the sites for alternative splicing of exons 2 and 3 of the SWAP mRNA. These proteins are thus thought to be involved in auto-regulation of pre-mRNA splicing. Most family members are associated with two Surp domains pfam01805 and an Arginine- serine-rich binding region towards the C-terminus.


Pssm-ID: 462881  Cd Length: 129  Bit Score: 102.39  E-value: 1.84e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423709     3 LEIVGRHALFFDDDSMATFVNSPTALVDWN---SLFIDRYDVRHLLS----SPPPPRIKRRRPNSNDADLESELDHERYL 75
Cdd:pfam09750   1 LQVFGRRCKLFRDDAIAAAAESGKHLVPWQgdpDLLIDRFDVRALLDdipeYEAGRSARLSELTSEEEEEERECNYERYR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 18423709    76 DLPSESPSPSDDDEH-----------DMNEDSANTNADGYRAVSFSYGS 113
Cdd:pfam09750  81 DLIKNEFEGVSEEEElkriyqeeqfgAKRLSAAKKSSGSYAAIGFSYDD 129
SWAP smart00648
Suppressor-of-White-APricot splicing regulator; domain present in regulators which are ...
 151-201 6.47e-14

Suppressor-of-White-APricot splicing regulator; domain present in regulators which are responsible for pre-mRNA splicing processes


Pssm-ID: 197818 [Multi-domain]  Cd Length: 54  Bit Score: 66.84  E-value: 6.47e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 18423709    151 HQIITRTSSFVSKHGGQSEIVLRVKQGDNPTFGFLMPDHHLHLYFRFLVDH 201
Cdd:smart00648   1 LDIIDKTAQFVARNGPEFEAKLMERERNNPQFDFLKPNDPYHAYYRKKLAE 51
SWAP smart00648
Suppressor-of-White-APricot splicing regulator; domain present in regulators which are ...
 336-389 3.12e-13

Suppressor-of-White-APricot splicing regulator; domain present in regulators which are responsible for pre-mRNA splicing processes


Pssm-ID: 197818 [Multi-domain]  Cd Length: 54  Bit Score: 64.92  E-value: 3.12e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 18423709    336 KRVIDKIVDFIQKNGKELEATLVAQDVKYGMFPFLRPSSLYHAYYRKVLQEAEE 389
Cdd:smart00648   1 LDIIDKTAQFVARNGPEFEAKLMERERNNPQFDFLKPNDPYHAYYRKKLAEYRQ 54
Surp pfam01805
Surp module; This domain is also known as the SWAP domain. SWAP stands for ...
 152-200 1.96e-11

Surp module; This domain is also known as the SWAP domain. SWAP stands for Suppressor-of-White-APricot. It has been suggested that these domains may be RNA binding.


Pssm-ID: 460339 [Multi-domain]  Cd Length: 52  Bit Score: 59.45  E-value: 1.96e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 18423709   152 QIITRTSSFVSKHGGQSEIVLRVKQGDNPTFGFLMP-DHHLHLYFRFLVD 200
Cdd:pfam01805   1 DIIKKTAQFVARNGPEFEALLMEREERNPQFDFLFDpDDPLHAYYRWKLE 50
Surp pfam01805
Surp module; This domain is also known as the SWAP domain. SWAP stands for ...
 337-386 9.11e-09

Surp module; This domain is also known as the SWAP domain. SWAP stands for Suppressor-of-White-APricot. It has been suggested that these domains may be RNA binding.


Pssm-ID: 460339 [Multi-domain]  Cd Length: 52  Bit Score: 52.14  E-value: 9.11e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 18423709   337 RVIDKIVDFIQKNGKELEATLVAQDVKYGMFPFLRPS-SLYHAYYRKVLQE 386
Cdd:pfam01805   1 DIIKKTAQFVARNGPEFEALLMEREERNPQFDFLFDPdDPLHAYYRWKLEE 51
 
Name Accession Description Interval E-value
DRY_EERY pfam09750
Alternative splicing regulator; This entry represents the conserved N-terminal region of SWAP ...
 3-113 1.84e-25

Alternative splicing regulator; This entry represents the conserved N-terminal region of SWAP (suppressor-of-white-apricot protein) proteins. This region contains two highly conserved motifs, viz: DRY and EERY, which appear to be the sites for alternative splicing of exons 2 and 3 of the SWAP mRNA. These proteins are thus thought to be involved in auto-regulation of pre-mRNA splicing. Most family members are associated with two Surp domains pfam01805 and an Arginine- serine-rich binding region towards the C-terminus.


Pssm-ID: 462881  Cd Length: 129  Bit Score: 102.39  E-value: 1.84e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423709     3 LEIVGRHALFFDDDSMATFVNSPTALVDWN---SLFIDRYDVRHLLS----SPPPPRIKRRRPNSNDADLESELDHERYL 75
Cdd:pfam09750   1 LQVFGRRCKLFRDDAIAAAAESGKHLVPWQgdpDLLIDRFDVRALLDdipeYEAGRSARLSELTSEEEEEERECNYERYR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 18423709    76 DLPSESPSPSDDDEH-----------DMNEDSANTNADGYRAVSFSYGS 113
Cdd:pfam09750  81 DLIKNEFEGVSEEEElkriyqeeqfgAKRLSAAKKSSGSYAAIGFSYDD 129
SWAP smart00648
Suppressor-of-White-APricot splicing regulator; domain present in regulators which are ...
 151-201 6.47e-14

Suppressor-of-White-APricot splicing regulator; domain present in regulators which are responsible for pre-mRNA splicing processes


Pssm-ID: 197818 [Multi-domain]  Cd Length: 54  Bit Score: 66.84  E-value: 6.47e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 18423709    151 HQIITRTSSFVSKHGGQSEIVLRVKQGDNPTFGFLMPDHHLHLYFRFLVDH 201
Cdd:smart00648   1 LDIIDKTAQFVARNGPEFEAKLMERERNNPQFDFLKPNDPYHAYYRKKLAE 51
SWAP smart00648
Suppressor-of-White-APricot splicing regulator; domain present in regulators which are ...
 336-389 3.12e-13

Suppressor-of-White-APricot splicing regulator; domain present in regulators which are responsible for pre-mRNA splicing processes


Pssm-ID: 197818 [Multi-domain]  Cd Length: 54  Bit Score: 64.92  E-value: 3.12e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 18423709    336 KRVIDKIVDFIQKNGKELEATLVAQDVKYGMFPFLRPSSLYHAYYRKVLQEAEE 389
Cdd:smart00648   1 LDIIDKTAQFVARNGPEFEAKLMERERNNPQFDFLKPNDPYHAYYRKKLAEYRQ 54
Surp pfam01805
Surp module; This domain is also known as the SWAP domain. SWAP stands for ...
 152-200 1.96e-11

Surp module; This domain is also known as the SWAP domain. SWAP stands for Suppressor-of-White-APricot. It has been suggested that these domains may be RNA binding.


Pssm-ID: 460339 [Multi-domain]  Cd Length: 52  Bit Score: 59.45  E-value: 1.96e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 18423709   152 QIITRTSSFVSKHGGQSEIVLRVKQGDNPTFGFLMP-DHHLHLYFRFLVD 200
Cdd:pfam01805   1 DIIKKTAQFVARNGPEFEALLMEREERNPQFDFLFDpDDPLHAYYRWKLE 50
Surp pfam01805
Surp module; This domain is also known as the SWAP domain. SWAP stands for ...
 337-386 9.11e-09

Surp module; This domain is also known as the SWAP domain. SWAP stands for Suppressor-of-White-APricot. It has been suggested that these domains may be RNA binding.


Pssm-ID: 460339 [Multi-domain]  Cd Length: 52  Bit Score: 52.14  E-value: 9.11e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 18423709   337 RVIDKIVDFIQKNGKELEATLVAQDVKYGMFPFLRPS-SLYHAYYRKVLQE 386
Cdd:pfam01805   1 DIIKKTAQFVARNGPEFEALLMEREERNPQFDFLFDPdDPLHAYYRWKLEE 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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