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Conserved domains on  [gi|18400264|ref|NP_565551|]
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cis-prenyltransferase [Arabidopsis thaliana]

Protein Classification

undecaprenyl diphosphate synthase family protein( domain architecture ID 10000255)

undecaprenyl diphosphate synthase (UPPS) family protein catalyzes consecutive condensation reactions of farnesyl diphosphate (FPP) with specific numbers of isopentenyl diphosphate (IPP) to form long-chain polyprenyl diphosphates, similar to UPPS that catalyzes chain elongation of FPP by eight IPP to form the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis

Gene Ontology:  GO:0016765|GO:0000287|GO:0002094
PubMed:  22471620

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
65-300 2.29e-116

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


:

Pssm-ID: 439791  Cd Length: 248  Bit Score: 335.10  E-value: 2.29e-116
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  65 LQRELMPRHVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSLIQH 144
Cdd:COG0020  10 IDPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLRE 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264 145 YRNKsNIKFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSEKGLIREE 224
Cdd:COG0020  90 YLRR-ELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGELDPE 168

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 18400264 225 DVDEALIERELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRFG 300
Cdd:COG0020 169 DIDEETISRYLYT--ADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRERRFG 242
 
Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
65-300 2.29e-116

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 335.10  E-value: 2.29e-116
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  65 LQRELMPRHVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSLIQH 144
Cdd:COG0020  10 IDPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLRE 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264 145 YRNKsNIKFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSEKGLIREE 224
Cdd:COG0020  90 YLRR-ELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGELDPE 168

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 18400264 225 DVDEALIERELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRFG 300
Cdd:COG0020 169 DIDEETISRYLYT--ADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRERRFG 242
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 77-300 3.35e-111

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 320.85  E-value: 3.35e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264    77 ILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSLIQHYRNKSNIKFFHR 156
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLKEEYLRRELPELHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   157 SEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSEKglIREEDVDEALIERELL 236
Cdd:pfam01255  81 NGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKEGKK--LDPEDIDEELISSHLY 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 18400264   237 TncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRFG 300
Cdd:pfam01255 159 T--AGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERRFG 220
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 73-294 2.83e-110

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 318.55  E-value: 2.83e-110
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  73 HVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSLIQHYRNKsNIK 152
Cdd:cd00475   1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEK-ELE 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264 153 FFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSEKGLIREEDVDEALIE 232
Cdd:cd00475  80 ELHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEELIS 159

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 18400264 233 RELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQR 294
Cdd:cd00475 160 KHLYT--ADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQR 219
PRK14831 PRK14831
undecaprenyl pyrophosphate synthase; Provisional
 64-300 1.28e-87

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184841  Cd Length: 249  Bit Score: 262.19  E-value: 1.28e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   64 GLQRELMPRHVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSLIQ 143
Cdd:PRK14831  14 DLDPQRLPKHVAVIMDGNGRWAKRRGLPRIMGHRRGVDALKDLLRCCKDWGIGALTAYAFSTENWSRPLEEVNFLMTLFE 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  144 HYRnKSNIKFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSEKGLIRE 223
Cdd:PRK14831  94 RVL-RRELEELMEENVRIRFVGDLDPLPKSLQEEISRSTELTKNNNGIHFNVCTNYGGRQEIVQAARAIAQQVQQGELDP 172

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 18400264  224 EDVDEALIERELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRFG 300
Cdd:PRK14831 173 SEIDENLFESELYT--AGIKDPDLLIRTSGEMRISNFLLWQLAYAEIYVTDVLWPDFDRDEFHKALLDYQSRERRFG 247
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 72-300 5.51e-83

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 249.63  E-value: 5.51e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264    72 RHVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSLIQHYRnKSNI 151
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKL-DREV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   152 KFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSEKGLIREEDVDEALI 231
Cdd:TIGR00055  80 KELHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLPEDIDEETL 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 18400264   232 ERELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRFG 300
Cdd:TIGR00055 160 NKHLYT--ANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
 
Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
65-300 2.29e-116

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 335.10  E-value: 2.29e-116
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  65 LQRELMPRHVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSLIQH 144
Cdd:COG0020  10 IDPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLRE 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264 145 YRNKsNIKFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSEKGLIREE 224
Cdd:COG0020  90 YLRR-ELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGELDPE 168

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 18400264 225 DVDEALIERELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRFG 300
Cdd:COG0020 169 DIDEETISRYLYT--ADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRERRFG 242
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 77-300 3.35e-111

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 320.85  E-value: 3.35e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264    77 ILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSLIQHYRNKSNIKFFHR 156
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLKEEYLRRELPELHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   157 SEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSEKglIREEDVDEALIERELL 236
Cdd:pfam01255  81 NGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKEGKK--LDPEDIDEELISSHLY 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 18400264   237 TncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRFG 300
Cdd:pfam01255 159 T--AGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERRFG 220
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 73-294 2.83e-110

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 318.55  E-value: 2.83e-110
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  73 HVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSLIQHYRNKsNIK 152
Cdd:cd00475   1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEK-ELE 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264 153 FFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSEKGLIREEDVDEALIE 232
Cdd:cd00475  80 ELHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEELIS 159

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 18400264 233 RELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQR 294
Cdd:cd00475 160 KHLYT--ADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQR 219
PRK14831 PRK14831
undecaprenyl pyrophosphate synthase; Provisional
 64-300 1.28e-87

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184841  Cd Length: 249  Bit Score: 262.19  E-value: 1.28e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   64 GLQRELMPRHVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSLIQ 143
Cdd:PRK14831  14 DLDPQRLPKHVAVIMDGNGRWAKRRGLPRIMGHRRGVDALKDLLRCCKDWGIGALTAYAFSTENWSRPLEEVNFLMTLFE 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  144 HYRnKSNIKFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSEKGLIRE 223
Cdd:PRK14831  94 RVL-RRELEELMEENVRIRFVGDLDPLPKSLQEEISRSTELTKNNNGIHFNVCTNYGGRQEIVQAARAIAQQVQQGELDP 172

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 18400264  224 EDVDEALIERELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRFG 300
Cdd:PRK14831 173 SEIDENLFESELYT--AGIKDPDLLIRTSGEMRISNFLLWQLAYAEIYVTDVLWPDFDRDEFHKALLDYQSRERRFG 247
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 65-300 3.89e-86

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 258.27  E-value: 3.89e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   65 LQRELMPRHVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSLIQH 144
Cdd:PRK14830  17 LDKGNIPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENWKRPKDEVKFLMNLPVE 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  145 YRNKSnIKFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSEKGLIREE 224
Cdd:PRK14830  97 FLDKF-VPELIENNVKVNVIGDTDRLPEHTLRALEKAIEKTKNNTGLILNFALNYGGRAEIVSAVKEIAKDVLDGKLNPE 175

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 18400264  225 DVDEALIERELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRFG 300
Cdd:PRK14830 176 DITEELISNYLMT--KGLPDPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLKAIKDYQSRQRRFG 249
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 72-300 5.51e-83

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 249.63  E-value: 5.51e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264    72 RHVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSLIQHYRnKSNI 151
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKL-DREV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   152 KFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSEKGLIREEDVDEALI 231
Cdd:TIGR00055  80 KELHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLPEDIDEETL 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 18400264   232 ERELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRFG 300
Cdd:TIGR00055 160 NKHLYT--ANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
PRK14836 PRK14836
undecaprenyl pyrophosphate synthase; Provisional
 71-300 9.94e-80

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237831  Cd Length: 253  Bit Score: 242.28  E-value: 9.94e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   71 PRHVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSL-IQHYRNKs 149
Cdd:PRK14836  15 PRHIAIIMDGNGRWAKRRGKPRVEGHRAGVRAVRRTIEFCLEKGIEMLTLFAFSSENWLRPADEVSALMELfLKALDRE- 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  150 nIKFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSEKGLIREEDVDEA 229
Cdd:PRK14836  94 -VDKLHRNGIRVRFIGDRSRLSPKLQERMEYAERLTASNTRLILSLAVSYGGRWDIVTAARALAREVAAGKLAPDEIDEA 172

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 18400264  230 LIERELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRFG 300
Cdd:PRK14836 173 LLAQHLAL--ADLPEPDLFIRTSGELRISNFLLWQLAYTELYFTDTLWPDFDAQELQQALEDYASRERRFG 241
PRK14832 PRK14832
undecaprenyl pyrophosphate synthase; Provisional
 58-300 6.70e-76

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237827  Cd Length: 253  Bit Score: 232.58  E-value: 6.70e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   58 YVVREDGLQRELMPRHVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDN 137
Cdd:PRK14832   6 YVMRPPDLDPQKIPQHIAVIMDGNGRWATSQGLPRIAGHRQGARTLKELLRCCKDWGIKALTAYAFSTENWQRPIEEVDF 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  138 LMSLIQHYRNKSnIKFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSE 217
Cdd:PRK14832  86 LMLLFERLLRRE-LAQMHREGVRISFIGDLSALPKSLQTEMERSMTETLNNQAIHFTVAVNYGSRNEITRACRQVAELVQ 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  218 KGLIREEDVDEALIERELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRER 297
Cdd:PRK14832 165 QGKLSADAVNEQLVEQHLYT--ADTPPPDLLIRTSGEMRLSNFLLWQMAYTEMYFTDILWPDFDRAAFHQALLSYQKRDR 242


                 ...
gi 18400264  298 RFG 300
Cdd:PRK14832 243 RFG 245
PRK14834 PRK14834
isoprenyl transferase;
71-300 4.11e-74

isoprenyl transferase;


Pssm-ID: 237829  Cd Length: 249  Bit Score: 227.71  E-value: 4.11e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   71 PRHVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSLIQHY-RNks 149
Cdd:PRK14834  15 PRHVAIIMDGNGRWAKARGLPRAAGHRAGVEALRRVVRAAGELGIGYLTLFAFSSENWSRPASEVSDLFGLLRLFiRR-- 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  150 NIKFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSEKGLIREEDVDEA 229
Cdd:PRK14834  93 DLAELHRNGVRVRVIGERAGLEADICALLNEAEELTRNNTGLNLVIAFNYGSRDEIARAVRRLAREVAEGRLDPASIDAE 172

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 18400264  230 LIERELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRFG 300
Cdd:PRK14834 173 TISANLDT--ADIPDPDLIIRTSGEQRLSNFLLWQAAYSELLFVPIHWPDFDKAALEAAIEEYARRERRFG 241
PRK14835 PRK14835
isoprenyl transferase;
62-300 1.59e-68

isoprenyl transferase;


Pssm-ID: 237830  Cd Length: 275  Bit Score: 214.32  E-value: 1.59e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   62 EDGLQREL----MPRHVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDN 137
Cdd:PRK14835  29 EQRLEREVkhgkLPRHLGLILDGNRRFARALGLQREMGHEFGVQKAYEVLEWCLELGIPTVTIWVFSTDNFSRSPAEVET 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  138 LMSL-IQHYRNKSNIKFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKS 216
Cdd:PRK14835 109 LMNLfEREARRMAVDPRIHANRVRVRAIGRHDGFPPKVLEALEELEERTEGHEGMLLNIAVGYGGREEIVDAVKSLLLEA 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  217 EKGLIREEDVDEAL----IERELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASY 292
Cdd:PRK14835 189 AATGKSPEEVAAELtpehISAHLYT--AGVPDPDFIIRTSGEIRLSGFLLWQSAYSEYYFCDVYWPGFRKVDFLRALRDY 266


                 ....*...
gi 18400264  293 QRRERRFG 300
Cdd:PRK14835 267 QGRERRFG 274
PRK14840 PRK14840
undecaprenyl pyrophosphate synthase; Provisional
 62-300 3.31e-68

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173301  Cd Length: 250  Bit Score: 212.78  E-value: 3.31e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   62 EDGLQRELMPRHVAFILDGNRRWAKR----AGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDN 137
Cdd:PRK14840  10 ENFPSLQSLPRHVAIIMDGNRRWYRKheqfCQKRAISGHYYGAKSLPQIVDTALHLGIEVLTLFAFSTENFSRSKEEVAE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  138 LMSLIqHYRNKSNIKFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSE 217
Cdd:PRK14840  90 LFSLF-NSQLDSQLPYLHENEIRLRCIGDLSKLPQELQNNIEQASSATAHYSRMELVLAINYGGKDELVRAFKKLHQDLA 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  218 KGLIREEDVDEALIERELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRER 297
Cdd:PRK14840 169 NKKISSDDISEELISSYLDT--SGLPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTPNDLLEAIKTYQQRSR 246


                 ...
gi 18400264  298 RFG 300
Cdd:PRK14840 247 RGG 249
PRK14839 PRK14839
di-trans,poly-cis-decaprenylcistransferase;
65-300 4.53e-68

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237832  Cd Length: 239  Bit Score: 211.92  E-value: 4.53e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   65 LQRELMPR---HVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSL 141
Cdd:PRK14839   1 MQSSLDRRsglHVAIIMDGNGRWATARGLPRLAGHRAGVEAIRRVVEAAPDLGIGTLTLYAFSSDNWRRPAAEVGGLMRL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  142 IQHY-RNKsnIKFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKslvkkseKGL 220
Cdd:PRK14839  81 LRAYlRNE--TERLARNGVRLTVIGRRDRLPDGIPEAIARAEAATAGGDRLHLRIAVDYSARDAILAAAA-------KAL 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  221 IREEDVDEALieRELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRFG 300
Cdd:PRK14839 152 GPEGLSREAF--SDLLT--GDGGDVDLLIRTGGEKRLSDFLLWESAYAELHFTDRMWPDFGADDLAAAVADFHGRERRFG 227
PRK14838 PRK14838
isoprenyl transferase;
70-300 3.64e-67

isoprenyl transferase;


Pssm-ID: 184846  Cd Length: 242  Bit Score: 209.73  E-value: 3.64e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   70 MPRHVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSLIQhyrNKS 149
Cdd:PRK14838  10 IPQHIAIIMDGNGRWAKERGKERSFGHQAGAETVHIITEEAARLGVKFLTLYTFSTENWNRPSDEVAALMSLLL---DSI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  150 NIKFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSEKGLIREEDVDEA 229
Cdd:PRK14838  87 EEETFMKNNIRFRIIGDIAKLPEEVQERLNECEEHTAKNTGMCLVLALSYSSRWEITEATRQIATLVQNGELNPEEITEE 166

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 18400264  230 LIERELLTNCsdFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRFG 300
Cdd:PRK14838 167 SISEHLTTNF--MPDPDLLIRTGGEIRLSNYLLWQCAYSELYFCDTFWPDFDEEELCKAIYDYQKRERRFG 235
PRK14833 PRK14833
di-trans,poly-cis-decaprenylcistransferase;
70-300 3.96e-67

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237828  Cd Length: 233  Bit Score: 209.28  E-value: 3.96e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   70 MPRHVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSLIQHYRnKS 149
Cdd:PRK14833   4 TLKHLAIIMDGNGRWAKLRGKARAAGHKKGVKTLREITIWCANHKLECLTLYAFSTENWKRPKSEVDFLMKLLKKYL-KD 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  150 NIKFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSEKGlIREEDVDEA 229
Cdd:PRK14833  83 ERSTYLENNIRFKAIGDLEGFSKELRDTILQLEEDTRSFKGFTQVLALNYGSKDEISRAFKKLLESPPSH-IGELESLEE 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 18400264  230 LIERELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRFG 300
Cdd:PRK14833 162 EISNCLDT--ADLPEVDLLIRTGGEMRLSNFLLWQSSYAELFFTPILWPDFTPKDLENIISDFYKRVRKFG 230
PRK14829 PRK14829
undecaprenyl pyrophosphate synthase; Provisional
 67-300 8.23e-66

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237826  Cd Length: 243  Bit Score: 206.56  E-value: 8.23e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   67 RELMPRHVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSL---IQ 143
Cdd:PRK14829  11 KNKLPRHIAVVMDGNGRWATQRGLKRTEGHKAGEPVLFDVVAGAIEAGVPYLSLYTFSTENWKRSPDEVRFLMGFsrdVI 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  144 HYRnksnIKFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSEKGLIRE 223
Cdd:PRK14829  91 HRR----REQMDEWGVRVRWSGRRPRLWKSVIDELEAAEELTKNNTTMDLVFCVNYGGRAEIADAAAAIAREVRDGKISG 166

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 18400264  224 EDVDEALIERELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRFG 300
Cdd:PRK14829 167 DRVTEKMISDHLYN--PDMPDVDLFLRTSGEQRTSNFLLWQSAYAELDFVPKLFPDFGRDDLWAAIDEYAHRDRRFG 241
PRK14841 PRK14841
undecaprenyl pyrophosphate synthase; Provisional
 70-300 1.10e-63

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173302  Cd Length: 233  Bit Score: 200.60  E-value: 1.10e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   70 MPRHVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSLIQHYRNKS 149
Cdd:PRK14841   3 IPQHVAIIMDGNGRWAKKRGLPRIKGHQRGAEVLHNTVKWSLELGIKYLTAFSFSTENWKRPKEEVEFLMDLFVQMIDRE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  150 nIKFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSEKGliREEDVDEA 229
Cdd:PRK14841  83 -MELLRRERVRVRILGRKEGLPEKVLKKWQEVEEKTKEFDRMTLVIAFNYGGRREILDAVESILKDVSQG--KKIELTEE 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 18400264  230 LIERELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRFG 300
Cdd:PRK14841 160 TFRQYLYL--PDVPDPDLIIRTSGEMRLSNFLLWQSAYSELYFFKKLWPDFTKRDFLRAIESYSKRERRFG 228
PRK10240 PRK10240
(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;
78-300 7.83e-59

(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;


Pssm-ID: 182326  Cd Length: 229  Bit Score: 188.27  E-value: 7.83e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   78 LDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSLIQHYRNkSNIKFFHRS 157
Cdd:PRK10240   1 MDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALD-SEVKSLHRH 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  158 EVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSEKGLIREEDVDEALIERELlt 237
Cdd:PRK10240  80 NVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEQVQQGNLQPDQIDEEMLNQHI-- 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 18400264  238 nCSDFPSP-DLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRFG 300
Cdd:PRK10240 158 -CMHELAPvDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGALNAFANRERRFG 220
PRK14828 PRK14828
undecaprenyl pyrophosphate synthase; Provisional
 58-300 3.34e-57

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237825  Cd Length: 256  Bit Score: 184.57  E-value: 3.34e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   58 YVVRE-DGLQRelmPRHVAFILDGNRRWAKRAGLTT-SQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEI 135
Cdd:PRK14828  16 RLLGElDGAQV---PGHVGIIVDGNRRWARKAGFTDvSQGHRAGAAKIGEFLGWCDETDVNVVTLYLLSTDNLGRPSEEL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  136 DNLMSLIQHY-RNKSNIKffhrsEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVK 214
Cdd:PRK14828  93 NPLLDIIEDVvRQLAPDG-----RWRVRHVGSLDLLPAPSANRLKEAEEATVGNDGIKVNVAVGYGGRQEIVDAVRSLLT 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  215 K-SEKGL-IRE--EDVDEALIERELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALA 290
Cdd:PRK14828 168 EhKDKGTsIDElaESVTVDAISTHLYT--GGQPDPDLVIRTSGEQRLSGFMLWQSAHSEYYFCETYWPAFRKVDFLRALR 245

                        250
                 ....*....|
gi 18400264  291 SYQRRERRFG 300
Cdd:PRK14828 246 DYSQRERRFG 255
PRK14827 PRK14827
undecaprenyl pyrophosphate synthase; Provisional
 70-300 8.45e-55

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173288  Cd Length: 296  Bit Score: 179.77  E-value: 8.45e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   70 MPRHVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSLIQHY--RN 147
Cdd:PRK14827  67 LPNHVAIVMDGNGRWATQRGLARTEGHKMGEAVVIDIACGAIELGIKWLSLYAFSTENWKRSPEEVRFLMGFNRDVvrRR 146

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  148 KSNIKffhRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSEKGLIREEDVD 227
Cdd:PRK14827 147 RDNLN---KMGVRIRWVGSRPRLWRSVINELAIAEEMTKSNDVITINYCVNYGGRTEITEATREIAREAAAGRLNPERIT 223

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 18400264  228 EALIERELltNCSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRFG 300
Cdd:PRK14827 224 ESTIARHL--QRPDIPDVDLFLRTSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACEEYASRNRRFG 294
PRK14842 PRK14842
undecaprenyl pyrophosphate synthase; Provisional
 64-300 1.27e-53

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173303  Cd Length: 241  Bit Score: 175.18  E-value: 1.27e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   64 GLQRELMPRHVAFILDGNRRWAKRAGLTTSQGHEAGAK---RLIDIAelcFELGVHTVSAFAFSTENWGRDKIEIDNLMS 140
Cdd:PRK14842   2 GLFESTIPAHIAVIMDGNGRWAESQGKKRSEGHREGANaidRLMDAS---LEYGLKNISLYAFSTENWKRPITEIRSIFG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  141 LIQHYRnKSNIKFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSL-VKKSEKG 219
Cdd:PRK14842  79 LLVEFI-ETRLDTIHARGIRIHHSGSRKKLTRTVLDKIDFAMAKTKKNKNLTVNFCLNYGSHDELLRAAQEVfLARKAKK 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  220 LIREEDVDEALIERELLTncSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRF 299
Cdd:PRK14842 158 VTLEKPLKEKEFEKFLYT--SPLPPVDLLIRTAGEQRLSNFLLWQSAYAELYFTDTLWPDFDKNSLVDSLKWYETRTRKF 235


                 .
gi 18400264  300 G 300
Cdd:PRK14842 236 G 236
PRK14837 PRK14837
undecaprenyl pyrophosphate synthase; Provisional
 70-300 2.82e-50

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173298  Cd Length: 230  Bit Score: 166.15  E-value: 2.82e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   70 MPRHVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEIDNLMSLIQHYRnKS 149
Cdd:PRK14837   6 LPSHVGIIMDGNRRWALKKGLSFFEGHKEGLKRAKEIVKHSLKLGIKYLSLYVFSTENWNRTDSEIEHLMFLIADYL-SS 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  150 NIKFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDIMHACKSLVKKSekglIREEDVDEA 229
Cdd:PRK14837  85 EFNFYKKNNIKIIVSGDIESLSEEVKKSIKDAISFTKNFDGLVLNLAINYGGRNEIVRAVKKFLSSG----LDLETLNEN 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 18400264  230 LIERELltNCSDFPSPDLMIRTSGEQRISNFFLWQLAYSELFFSPVFWPDFDKDKLLEALASYQRRERRFG 300
Cdd:PRK14837 161 VFSKFL--DNPELPDLDLLIRTGGDMRISNFLLWRIAYCEFIFSNVLWPEYYVNHYSKDLECFKNRKRNFG 229
PTZ00349 PTZ00349
dehydrodolichyl diphosphate synthetase; Provisional
 72-281 1.35e-34

dehydrodolichyl diphosphate synthetase; Provisional


Pssm-ID: 185571  Cd Length: 322  Bit Score: 127.81  E-value: 1.35e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264   72 RHVAFILDGNRRWAKRAGLTTSQGHEAGAKRLIDIAELCFELGVHTVSAFAFSTENWGRDKIEID-----NLMSLIQHyr 146
Cdd:PTZ00349  21 KHISIIMDGNRRFAKEKGLHSAIGHFMGSKALIQIIEICIKLKIKILSVFSFSLLNYNRSPEEIHflfylNLLILINE-- 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  147 nKSNIKFFHRSEVRVSVIGNKTKIPESLLKEIHEIEEATKGYKNKHLIMAVDYSGKFDiMHACK---SLVKKSEKGLIRE 223
Cdd:PTZ00349  99 -DFFFKFIKDNKIKIKIIGNLSYINDAYRKIIHDIEEKTENFDNILLNIFFSYTSRNE-MSLCKfnpNLYFDTYKNLLEE 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400264  224 EDV-------------------------------------------------------DEALIE-----RELLTncSDFP 243
Cdd:PTZ00349 177 KKIlcgsniltdpikegtfaipddedecdyldheleneridldlkfdgdcicgeksflNEEQIEivnyhKKLLT--SDLP 254

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 18400264  244 SPDLMIRTSGEQRISNFFLWQLA-YSELFFSPVFWPDFD 281
Cdd:PTZ00349 255 PPNILIRTSGEKRLSDFMLYQISeFTEIYFINEYWPIFN 293
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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