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Conserved domains on  [gi|1063678598|ref|NP_564738|]
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GDSL-like Lipase/Acylhydrolase superfamily protein [Arabidopsis thaliana]

Protein Classification

SGNH/GDSL hydrolase family protein( domain architecture ID 10110850)

SGNH/GDSL hydrolase family protein is a hydrolytic enzyme such as an esterase or lipase; may have multifunctional properties including broad substrate specificity and regiospecificity

CATH:  3.40.50.1110
EC:  3.1.-.-
Gene Ontology:  GO:0016788
PubMed:  15522763|35871440
SCOP:  3001315

Graphical summary

 Zoom to residue level

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Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
SGNH_plant_lipase_like cd01837
SGNH_plant_lipase_like, a plant specific subfamily of the SGNH-family of hydrolases, a diverse ...
29-344 4.64e-144

SGNH_plant_lipase_like, a plant specific subfamily of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.


:

Pssm-ID: 238875 [Multi-domain]  Cd Length: 315  Bit Score: 409.70  E-value: 4.64e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598  29 PALIVFGDSIMDTGNNNNLPTLLKCNFPPYGKDYPGGfATGRFSDGRVPSDLIAEKLGLAKTLPAYMNPYLKpEDLLKGV 108
Cdd:cd01837     1 PALFVFGDSLVDTGNNNYLPTLAKANFPPYGIDFPGR-PTGRFSNGRLIIDFIAEALGLPLLPPPYLSPNGS-SDFLTGV 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 109 TFASGGTGYDPLTAKIMSVISVWDQLINFKEYISKIKRHFGEEKAKDILEHSFFLVVSSSNDLAHTYLA-QTHRYDRTSY 187
Cdd:cd01837    79 NFASGGAGILDSTGFLGSVISLSVQLEYFKEYKERLRALVGEEAAADILSKSLFLISIGSNDYLNNYFAnPTRQYEVEAY 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 188 ANFLADSAVHFVRELHKLGARKIGVFSAVPVGCVPLQRTVFGGFfTRGCNQPLNNMAKQFNARLSPALDSLDKELDGV-I 266
Cdd:cd01837   159 VPFLVSNISSAIKRLYDLGARKFVVPGLGPLGCLPSQRTLFGGD-GGGCLEELNELARLFNAKLKKLLAELRRELPGAkF 237
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063678598 267 LYINVYDTLFDMIQHPKKYGFEVADRGCCGKGLLAISYLCNSLNPFTCSNSSAYIFWDSYHPSERAYQVIVDNLLDKY 344
Cdd:cd01837   238 VYADIYNALLDLIQNPAKYGFENTLKACCGTGGPEGGLLCNPCGSTVCPDPSKYVFWDGVHPTEAANRIIADALLSGP 315
 
Name Accession Description Interval E-value
SGNH_plant_lipase_like cd01837
SGNH_plant_lipase_like, a plant specific subfamily of the SGNH-family of hydrolases, a diverse ...
29-344 4.64e-144

SGNH_plant_lipase_like, a plant specific subfamily of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.


Pssm-ID: 238875 [Multi-domain]  Cd Length: 315  Bit Score: 409.70  E-value: 4.64e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598  29 PALIVFGDSIMDTGNNNNLPTLLKCNFPPYGKDYPGGfATGRFSDGRVPSDLIAEKLGLAKTLPAYMNPYLKpEDLLKGV 108
Cdd:cd01837     1 PALFVFGDSLVDTGNNNYLPTLAKANFPPYGIDFPGR-PTGRFSNGRLIIDFIAEALGLPLLPPPYLSPNGS-SDFLTGV 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 109 TFASGGTGYDPLTAKIMSVISVWDQLINFKEYISKIKRHFGEEKAKDILEHSFFLVVSSSNDLAHTYLA-QTHRYDRTSY 187
Cdd:cd01837    79 NFASGGAGILDSTGFLGSVISLSVQLEYFKEYKERLRALVGEEAAADILSKSLFLISIGSNDYLNNYFAnPTRQYEVEAY 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 188 ANFLADSAVHFVRELHKLGARKIGVFSAVPVGCVPLQRTVFGGFfTRGCNQPLNNMAKQFNARLSPALDSLDKELDGV-I 266
Cdd:cd01837   159 VPFLVSNISSAIKRLYDLGARKFVVPGLGPLGCLPSQRTLFGGD-GGGCLEELNELARLFNAKLKKLLAELRRELPGAkF 237
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063678598 267 LYINVYDTLFDMIQHPKKYGFEVADRGCCGKGLLAISYLCNSLNPFTCSNSSAYIFWDSYHPSERAYQVIVDNLLDKY 344
Cdd:cd01837   238 VYADIYNALLDLIQNPAKYGFENTLKACCGTGGPEGGLLCNPCGSTVCPDPSKYVFWDGVHPTEAANRIIADALLSGP 315
PLN03156 PLN03156
GDSL esterase/lipase; Provisional
1-347 1.03e-123

GDSL esterase/lipase; Provisional


Pssm-ID: 178701  Cd Length: 351  Bit Score: 359.44  E-value: 1.03e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598   1 MKIQILLFALVLIFVEANAATQGKnttIPALIVFGDSIMDTGNNNNLPTLLKCNFPPYGKDYPGGFATGRFSDGRVPSDL 80
Cdd:PLN03156    3 MHLFLIFFLLLAQLLVLVAETCAK---VPAIIVFGDSSVDAGNNNQISTVAKSNFEPYGRDFPGGRPTGRFCNGRIAPDF 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598  81 IAEKLGLAKTLPAYMNPYLKPEDLLKGVTFASGGTGYDPLTAKIMSVISVWDQLINFKEYISKIKRHFGEEKAKDILEHS 160
Cdd:PLN03156   80 ISEAFGLKPAIPAYLDPSYNISDFATGVCFASAGTGYDNATSDVLSVIPLWKELEYYKEYQTKLRAYLGEEKANEIISEA 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 161 FFLVVSSSNDLAHTYLAQTHR---YDRTSYANFLADSAVHFVRELHKLGARKIGVFSAVPVGCVPLQRT--VFGGFftrG 235
Cdd:PLN03156  160 LYLISIGTNDFLENYYTFPGRrsqYTVSQYQDFLIGIAENFVKKLYRLGARKISLGGLPPMGCLPLERTtnLMGGS---E 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 236 CNQPLNNMAKQFNARLSPALDSLDKELDGV-ILYINVYDTLFDMIQHPKKYGFEVADRGCCGKGLLAISYLCNSLNPFTC 314
Cdd:PLN03156  237 CVEEYNDVALEFNGKLEKLVTKLNKELPGIkLVFSNPYDIFMQIIRNPSAYGFEVTSVACCATGMFEMGYLCNRNNPFTC 316
                         330       340       350
                  ....*....|....*....|....*....|...
gi 1063678598 315 SNSSAYIFWDSYHPSERAYQVIVDNLLDKYLSK 347
Cdd:PLN03156  317 SDADKYVFWDSFHPTEKTNQIIANHVVKTLLSK 349
COG3240 COG3240
Phospholipase/lecithinase/hemolysin [Lipid transport and metabolism, General function ...
1-342 6.59e-26

Phospholipase/lecithinase/hemolysin [Lipid transport and metabolism, General function prediction only];


Pssm-ID: 442472 [Multi-domain]  Cd Length: 305  Bit Score: 105.12  E-value: 6.59e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598   1 MKIQILLFALVLIFVEANAATQGKNTTIPALIVFGDSIMDTGNNNNLpTLLKCNFPPYgkdypggfATGRFSDGRVPSDL 80
Cdd:COG3240     1 MKKRLAAALALLALLLAACGGAASAAAFSRIVVFGDSLSDTGNLFNL-TGGLPPSPPY--------FGGRFSNGPVWVEY 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598  81 IAEKLGLAKTLPAymnpylkpedlLKGVTFASGG--TGYDPLTA-KIMSVISVWDQLINFkeyiskIKRHFGEEKAKDIl 157
Cdd:COG3240    72 LAAALGLPLTPSS-----------AGGTNYAVGGarTGDGNGVLgGAALLPGLAQQVDAY------LAAAGGTADPNAL- 133
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 158 ehsfFLVVSSSND-LAHTYLAQTHRYDRTSYANFLADSAVHFVRELHKLGARKIGVFSAVPVGCVPlqrtvfggfFTRGC 236
Cdd:COG3240   134 ----YIVWAGANDlLAALAAVGATPAQAQAAATAAAANLAAAVGALAAAGARHILVPNLPDLGLTP---------AAQAL 200
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 237 NQP----LNNMAKQFNARLSPALDSLDKEldgvILYINVYDTLFDMIQHPKKYGFEVADRGCcgkgllaisyLCNSLNPF 312
Cdd:COG3240   201 GAAaaalLSALTAAFNQALAAALPALGVN----IILFDVNSLFNEIIANPAAYGFTNVTDAC----------LSGTVSAL 266
                         330       340       350
                  ....*....|....*....|....*....|.
gi 1063678598 313 TC-SNSSAYIFWDSYHPSERAYQVIVDNLLD 342
Cdd:COG3240   267 LCvANPDTYLFWDGVHPTTAAHRLIADYAYS 297
Lipase_GDSL pfam00657
GDSL-like Lipase/Acylhydrolase;
31-340 1.49e-16

GDSL-like Lipase/Acylhydrolase;


Pssm-ID: 459892 [Multi-domain]  Cd Length: 210  Bit Score: 77.23  E-value: 1.49e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598  31 LIVFGDSIMDTGNNNNlptllkcnfppygkdypggfaTGRFSDGRVPSDLIAEKLGLAKtlpaymnpylkpEDLLKGVTF 110
Cdd:pfam00657   1 IVAFGDSLTDGGGDGP---------------------GGRFSWGDLLADFLARKLGVPG------------SGYNHGANF 47
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 111 ASGGTGYDPLtakimsvisvWDQLINFKEYISKIKRHFGEekakdilehSFFLVVSSSNDLAHTYlaqthrYDRTSYANF 190
Cdd:pfam00657  48 AIGGATIEDL----------PIQLEQLLRLISDVKDQAKP---------DLVTIFIGANDLCNFL------SSPARSKKR 102
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 191 LADSAVHFVRELHKL--GARKIGVFSAVPVGCVPLQrtvfggfftrGCNQPLNNMAKQFNARLSPALDSLDKELDGVily 268
Cdd:pfam00657 103 VPDLLDELRANLPQLglGARKFWVHGLGPLGCTPPK----------GCYELYNALAEEYNERLNELVNSLAAAAEDA--- 169
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1063678598 269 iNVydTLFDMiqhpkkYGFEVADRGCCGKGLLAisylcnslnpftcsnssayifwDSYHPSERAYQVIVDNL 340
Cdd:pfam00657 170 -NV--VYVDI------YGFEDPTDPCCGIGLEP----------------------DGLHPSEKGYKAVAEAI 210
 
Name Accession Description Interval E-value
SGNH_plant_lipase_like cd01837
SGNH_plant_lipase_like, a plant specific subfamily of the SGNH-family of hydrolases, a diverse ...
29-344 4.64e-144

SGNH_plant_lipase_like, a plant specific subfamily of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.


Pssm-ID: 238875 [Multi-domain]  Cd Length: 315  Bit Score: 409.70  E-value: 4.64e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598  29 PALIVFGDSIMDTGNNNNLPTLLKCNFPPYGKDYPGGfATGRFSDGRVPSDLIAEKLGLAKTLPAYMNPYLKpEDLLKGV 108
Cdd:cd01837     1 PALFVFGDSLVDTGNNNYLPTLAKANFPPYGIDFPGR-PTGRFSNGRLIIDFIAEALGLPLLPPPYLSPNGS-SDFLTGV 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 109 TFASGGTGYDPLTAKIMSVISVWDQLINFKEYISKIKRHFGEEKAKDILEHSFFLVVSSSNDLAHTYLA-QTHRYDRTSY 187
Cdd:cd01837    79 NFASGGAGILDSTGFLGSVISLSVQLEYFKEYKERLRALVGEEAAADILSKSLFLISIGSNDYLNNYFAnPTRQYEVEAY 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 188 ANFLADSAVHFVRELHKLGARKIGVFSAVPVGCVPLQRTVFGGFfTRGCNQPLNNMAKQFNARLSPALDSLDKELDGV-I 266
Cdd:cd01837   159 VPFLVSNISSAIKRLYDLGARKFVVPGLGPLGCLPSQRTLFGGD-GGGCLEELNELARLFNAKLKKLLAELRRELPGAkF 237
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063678598 267 LYINVYDTLFDMIQHPKKYGFEVADRGCCGKGLLAISYLCNSLNPFTCSNSSAYIFWDSYHPSERAYQVIVDNLLDKY 344
Cdd:cd01837   238 VYADIYNALLDLIQNPAKYGFENTLKACCGTGGPEGGLLCNPCGSTVCPDPSKYVFWDGVHPTEAANRIIADALLSGP 315
PLN03156 PLN03156
GDSL esterase/lipase; Provisional
1-347 1.03e-123

GDSL esterase/lipase; Provisional


Pssm-ID: 178701  Cd Length: 351  Bit Score: 359.44  E-value: 1.03e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598   1 MKIQILLFALVLIFVEANAATQGKnttIPALIVFGDSIMDTGNNNNLPTLLKCNFPPYGKDYPGGFATGRFSDGRVPSDL 80
Cdd:PLN03156    3 MHLFLIFFLLLAQLLVLVAETCAK---VPAIIVFGDSSVDAGNNNQISTVAKSNFEPYGRDFPGGRPTGRFCNGRIAPDF 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598  81 IAEKLGLAKTLPAYMNPYLKPEDLLKGVTFASGGTGYDPLTAKIMSVISVWDQLINFKEYISKIKRHFGEEKAKDILEHS 160
Cdd:PLN03156   80 ISEAFGLKPAIPAYLDPSYNISDFATGVCFASAGTGYDNATSDVLSVIPLWKELEYYKEYQTKLRAYLGEEKANEIISEA 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 161 FFLVVSSSNDLAHTYLAQTHR---YDRTSYANFLADSAVHFVRELHKLGARKIGVFSAVPVGCVPLQRT--VFGGFftrG 235
Cdd:PLN03156  160 LYLISIGTNDFLENYYTFPGRrsqYTVSQYQDFLIGIAENFVKKLYRLGARKISLGGLPPMGCLPLERTtnLMGGS---E 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 236 CNQPLNNMAKQFNARLSPALDSLDKELDGV-ILYINVYDTLFDMIQHPKKYGFEVADRGCCGKGLLAISYLCNSLNPFTC 314
Cdd:PLN03156  237 CVEEYNDVALEFNGKLEKLVTKLNKELPGIkLVFSNPYDIFMQIIRNPSAYGFEVTSVACCATGMFEMGYLCNRNNPFTC 316
                         330       340       350
                  ....*....|....*....|....*....|...
gi 1063678598 315 SNSSAYIFWDSYHPSERAYQVIVDNLLDKYLSK 347
Cdd:PLN03156  317 SDADKYVFWDSFHPTEKTNQIIANHVVKTLLSK 349
fatty_acyltransferase_like cd01846
Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and ...
31-342 4.37e-32

Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases. Might catalyze fatty acid transfer between phosphatidylcholine and sterols.


Pssm-ID: 238882 [Multi-domain]  Cd Length: 270  Bit Score: 120.95  E-value: 4.37e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598  31 LIVFGDSIMDTGNnnnLPTLLKCNFPPYGKDYPGGfatgRFSDGRVPSDLIAEKLGLAKTLPAYmNpylkpedllkgvtF 110
Cdd:cd01846     2 LVVFGDSLSDTGN---IFKLTGGSNPPPSPPYFGG----RFSNGPVWVEYLAATLGLSGLKQGY-N-------------Y 60
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 111 ASGG--TGYDPLTAKIMSVISVWDQLINFKEYiskikrHFGEEKAKDIlehsfFLVVSSSNDL-AHTYLAQTHRYDRTSY 187
Cdd:cd01846    61 AVGGatAGAYNVPPYPPTLPGLSDQVAAFLAA------HKLRLPPDTL-----VAIWIGANDLlNALDLPQNPDTLVTRA 129
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 188 ANFLADSavhfVRELHKLGARKIGVFSAVPVGcvplqRTVFGGFFTRGCNQPLNNMAKQFNARLSPALDSLDKELDGV-I 266
Cdd:cd01846   130 VDNLFQA----LQRLYAAGARNFLVLNLPDLG-----LTPAFQAQGDAVAARATALTAAYNAKLAEKLAELKAQHPGVnI 200
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1063678598 267 LYINVYDTLFDMIQHPKKYGFEVADRGCcgkgllaISYLCNSLNPFTCSNSSAYIFWDSYHPSERAYQVIVDNLLD 342
Cdd:cd01846   201 LLFDTNALFNDILDNPAAYGFTNVTDPC-------LDYVYSYSPREACANPDKYLFWDEVHPTTAVHQLIAEEVAA 269
COG3240 COG3240
Phospholipase/lecithinase/hemolysin [Lipid transport and metabolism, General function ...
1-342 6.59e-26

Phospholipase/lecithinase/hemolysin [Lipid transport and metabolism, General function prediction only];


Pssm-ID: 442472 [Multi-domain]  Cd Length: 305  Bit Score: 105.12  E-value: 6.59e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598   1 MKIQILLFALVLIFVEANAATQGKNTTIPALIVFGDSIMDTGNNNNLpTLLKCNFPPYgkdypggfATGRFSDGRVPSDL 80
Cdd:COG3240     1 MKKRLAAALALLALLLAACGGAASAAAFSRIVVFGDSLSDTGNLFNL-TGGLPPSPPY--------FGGRFSNGPVWVEY 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598  81 IAEKLGLAKTLPAymnpylkpedlLKGVTFASGG--TGYDPLTA-KIMSVISVWDQLINFkeyiskIKRHFGEEKAKDIl 157
Cdd:COG3240    72 LAAALGLPLTPSS-----------AGGTNYAVGGarTGDGNGVLgGAALLPGLAQQVDAY------LAAAGGTADPNAL- 133
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 158 ehsfFLVVSSSND-LAHTYLAQTHRYDRTSYANFLADSAVHFVRELHKLGARKIGVFSAVPVGCVPlqrtvfggfFTRGC 236
Cdd:COG3240   134 ----YIVWAGANDlLAALAAVGATPAQAQAAATAAAANLAAAVGALAAAGARHILVPNLPDLGLTP---------AAQAL 200
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 237 NQP----LNNMAKQFNARLSPALDSLDKEldgvILYINVYDTLFDMIQHPKKYGFEVADRGCcgkgllaisyLCNSLNPF 312
Cdd:COG3240   201 GAAaaalLSALTAAFNQALAAALPALGVN----IILFDVNSLFNEIIANPAAYGFTNVTDAC----------LSGTVSAL 266
                         330       340       350
                  ....*....|....*....|....*....|.
gi 1063678598 313 TC-SNSSAYIFWDSYHPSERAYQVIVDNLLD 342
Cdd:COG3240   267 LCvANPDTYLFWDGVHPTTAAHRLIADYAYS 297
Lipase_GDSL pfam00657
GDSL-like Lipase/Acylhydrolase;
31-340 1.49e-16

GDSL-like Lipase/Acylhydrolase;


Pssm-ID: 459892 [Multi-domain]  Cd Length: 210  Bit Score: 77.23  E-value: 1.49e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598  31 LIVFGDSIMDTGNNNNlptllkcnfppygkdypggfaTGRFSDGRVPSDLIAEKLGLAKtlpaymnpylkpEDLLKGVTF 110
Cdd:pfam00657   1 IVAFGDSLTDGGGDGP---------------------GGRFSWGDLLADFLARKLGVPG------------SGYNHGANF 47
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 111 ASGGTGYDPLtakimsvisvWDQLINFKEYISKIKRHFGEekakdilehSFFLVVSSSNDLAHTYlaqthrYDRTSYANF 190
Cdd:pfam00657  48 AIGGATIEDL----------PIQLEQLLRLISDVKDQAKP---------DLVTIFIGANDLCNFL------SSPARSKKR 102
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 191 LADSAVHFVRELHKL--GARKIGVFSAVPVGCVPLQrtvfggfftrGCNQPLNNMAKQFNARLSPALDSLDKELDGVily 268
Cdd:pfam00657 103 VPDLLDELRANLPQLglGARKFWVHGLGPLGCTPPK----------GCYELYNALAEEYNERLNELVNSLAAAAEDA--- 169
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1063678598 269 iNVydTLFDMiqhpkkYGFEVADRGCCGKGLLAisylcnslnpftcsnssayifwDSYHPSERAYQVIVDNL 340
Cdd:pfam00657 170 -NV--VYVDI------YGFEDPTDPCCGIGLEP----------------------DGLHPSEKGYKAVAEAI 210
Triacylglycerol_lipase_like cd01847
Triacylglycerol lipase-like subfamily of the SGNH hydrolases, a diverse family of lipases and ...
30-342 4.69e-09

Triacylglycerol lipase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases. Members of this subfamily might hydrolyze triacylglycerol into diacylglycerol and fatty acid anions.


Pssm-ID: 238883  Cd Length: 281  Bit Score: 56.67  E-value: 4.69e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598  30 ALIVFGDSIMDTGNNNNLPtllkcnfppygkdyPGGFATGRFS--DGRVPSDLIAEKLGLAktlPAYMNPYLKPedllkG 107
Cdd:cd01847     3 RVVVFGDSLSDVGTYNRAG--------------VGAAGGGRFTvnDGSIWSLGVAEGYGLT---TGTATPTTPG-----G 60
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 108 VTFASGG----TGYDPLTAKImSVISVWDQLINFKeyiskiKRHFGeeKAKDILehsfFLVVSSSNDLAhTYLAQTHRY- 182
Cdd:cd01847    61 TNYAQGGarvgDTNNGNGAGA-VLPSVTTQIANYL------AAGGG--FDPNAL----YTVWIGGNDLI-AALAALTTAt 126
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 183 ----DRTSYANFLADSAVHFVRELHKLGARKIGVFSAVPVGCVPlqrtvFGGFFTRGCNQPLNNMAKQFNARLSPALDSL 258
Cdd:cd01847   127 ttqaAAVAAAATAAADLASQVKNLLDAGARYILVPNLPDVSYTP-----EAAGTPAAAAALASALSQTYNQTLQSGLNQL 201
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678598 259 DKELdgvILYINVYDTLFDMIQHPKKYGFeVADRGCCGKGLLAISYLCNSLNPFTCSNSsaYIFWDSYHPSERAYQVIVD 338
Cdd:cd01847   202 GANN---IIYVDTATLLKEVVANPAAYGF-TNTTTPACTSTSAAGSGAATLVTAAAQST--YLFADDVHPTPAGHKLIAQ 275

                  ....
gi 1063678598 339 NLLD 342
Cdd:cd01847   276 YALS 279
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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