Cupredoxin superfamily; Cupredoxins contain type I copper centers and are involved in inter-molecular electron transfer reactions. Cupredoxins are blue copper proteins, having an intense blue color due to the presence of a mononuclear type 1 (T1) copper site. Structurally, the cupredoxin-like fold consists of a beta-sandwich with 7 strands in 2 beta-sheets, which is arranged in a Greek-key beta-barrel. Some of these proteins have lost the ability to bind copper. The majority of family members contain multiple cupredoxin domain repeats: ceruloplasmin and the coagulation factors V/VIII have six repeats; laccase, ascorbate oxidase, spore coat protein A, and multicopper oxidase CueO contain three repeats; and nitrite reductase has two repeats. Others are mono-domain cupredoxins, such as plastocyanin, pseudoazurin, plantacyanin, azurin, rusticyanin, stellacyanin, quinol oxidase, and the periplasmic domain of cytochrome c oxidase subunit II.

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394953  30 ATFLVDGVSVWKSP----------TVHTGDSVIFRHKYGYDLYIFRNKDAFNVCNFTQATLLTKPNSTSFTwyPSRTGSY 99
Cdd:cd04216   1 TDYTVGDSNGWDLPvnytawasgkTFRVGDSLVFNYNAGAHSVVEVNEADYDSCDTSNPINTYTSGNDSVT--LTKPGTR 78

                        90       100
                ....*....|....*....|....
gi 18394953 100 YFSFTNNTSlpktCQLNQKLTVQV 123
Cdd:cd04216  79 YFICGVPGH----CQSGMKLAINV 98

Phytocyanins are plant blue or type I copper proteins; Phytocyanins are plant blue or type I copper proteins. They are involved in electron transfer reactions with the Cu center transitioning between the oxidized Cu(II) form and the reduced Cu(I) form. Phytocyanins are classified into four groups: stellacyanin, plantacyanin, uclacyanin and early nodulin groups. Stellacyanin appears to be associated with the plant cell wall; it may be involved in oxidative reactions to build polymeric material making up the cell wall. Plantacyanin is shown to play a role in reproduction in Arabidopsis. Plantacyanins may also be stress-related proteins and may be involved in plant defense responses. The early nodulin-like protein (OsENODL1) from Oryza sativa is expressed specifically at the late developmental stage of the seeds.

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394953  30 ATFLVDGVSVWKSP----------TVHTGDSVIFRHKYGYDLYIFRNKDAFNVCNFTQATLLTKPNSTSFTwyPSRTGSY 99
Cdd:cd04216   1 TDYTVGDSNGWDLPvnytawasgkTFRVGDSLVFNYNAGAHSVVEVNEADYDSCDTSNPINTYTSGNDSVT--LTKPGTR 78

                        90       100
                ....*....|....*....|....
gi 18394953 100 YFSFTNNTSlpktCQLNQKLTVQV 123
Cdd:cd04216  79 YFICGVPGH----CQSGMKLAINV 98

Histone deacetylase complex subunit SAP130 C-terminus;

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394953   105 NNTSLPKTCQLNQklTVQVILAAASPPSQPPA-----------TAPVPVSEGGVISSPSsypwplgpregsafSPGPS-- 171
Cdd:pfam16014  50 TASASPPSQHPAQ--AIPTILAPAAPPSQPSVvlstlpaamavTPPIPASMANVVAPPT--------------QPAASst 113

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 18394953   172 PSEITSVTVPG---KDGVPFINSNPAVPLPTgdvdSTSINPLPTSTNSA 217
Cdd:pfam16014 114 AACAVSSVLPEikiKQEAEPMDTSQSVPPLT----PTSISPALTSLANN 158

Phytocyanins are plant blue or type I copper proteins; Phytocyanins are plant blue or type I copper proteins. They are involved in electron transfer reactions with the Cu center transitioning between the oxidized Cu(II) form and the reduced Cu(I) form. Phytocyanins are classified into four groups: stellacyanin, plantacyanin, uclacyanin and early nodulin groups. Stellacyanin appears to be associated with the plant cell wall; it may be involved in oxidative reactions to build polymeric material making up the cell wall. Plantacyanin is shown to play a role in reproduction in Arabidopsis. Plantacyanins may also be stress-related proteins and may be involved in plant defense responses. The early nodulin-like protein (OsENODL1) from Oryza sativa is expressed specifically at the late developmental stage of the seeds.

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394953  30 ATFLVDGVSVWKSP----------TVHTGDSVIFRHKYGYDLYIFRNKDAFNVCNFTQATLLTKPNSTSFTwyPSRTGSY 99
Cdd:cd04216   1 TDYTVGDSNGWDLPvnytawasgkTFRVGDSLVFNYNAGAHSVVEVNEADYDSCDTSNPINTYTSGNDSVT--LTKPGTR 78

                        90       100
                ....*....|....*....|....
gi 18394953 100 YFSFTNNTSlpktCQLNQKLTVQV 123
Cdd:cd04216  79 YFICGVPGH----CQSGMKLAINV 98

large tegument protein UL36; Provisional

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394953   127 AASPPSQPPATAPVPVSEGGVISSPSSYPWPLGPREGSAFSPGPS---PSEITSVTVPGKDGVP-FINSNPAVPLPTGDV 202
Cdd:PHA03247 2912 QAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSgavPQPWLGALVPGRVAVPrFRVPQPAPSREAPAS 2991

                          90
                  ....*....|....*
gi 18394953   203 DSTSINPLPTSTNSA 217
Cdd:PHA03247 2992 STPPLTGHSLSRVSS 3006

Mavicyanin is a subclass of phytocyanins, a plant blue copper protein; Mavicyanin is a glycosylated protein isolated from Cucurbita pepo medullosa (zucchini) peelings. It belongs to the phytocyanin family of blue copper proteins, a ubiquitous family of plant cupredoxins. Mavicyanin is involved in electron transfer reactions with the Cu center transitioning between the oxidized Cu(II) form and the reduced Cu(I) form. The copper is tetrahedrally coordinated by a cysteine, 2 histidines, and a glutamine residue, like in the case of stellacyanin. The biological roles of mavicyanin have not been elucidated yet.

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394953  41 KSPTVHTGDSVIFrhKYGYDLYIFR--NKDAFNVCN--FTQATLLTKPNSTSFTwypsRTGSYYFSftnnTSLPKTCQLN 116
Cdd:cd11014  24 SSKTFHVGDSLIF--QYNKEFHDVTevTGEEFESCNstSPIAVYNTGHDIIKLT----KPGQYYFI----CGVPGHCDSG 93

                ....*..
gi 18394953 117 QKLTVQV 123
Cdd:cd11014  94 QKLQVNV 100