|
Name |
Accession |
Description |
Interval |
E-value |
| SRP54_euk |
TIGR01425 |
signal recognition particle protein SRP54; This model represents examples from the eukaryotic ... |
2-426 |
0e+00 |
|
signal recognition particle protein SRP54; This model represents examples from the eukaryotic cytosol of the signal recognition particle protein component, SRP54. This GTP-binding protein is a component of the eukaryotic signal recognition particle, along with several other protein subunits and a 7S RNA. Some species, including Arabidopsis, have several closely related forms. The extreme C-terminal region is glycine-rich and lower in complexity, poorly conserved between species, and excluded from this model.
Pssm-ID: 273615 [Multi-domain] Cd Length: 428 Bit Score: 659.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 2 VLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFK 81
Cdd:TIGR01425 1 VLAQLGSSLVTALRSMSSATVIDEEVINTMLKEICTALLESDVNPKLVRQMRNNIKKKINLEDIASGINKRKLIQDAVFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 82 ELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYG 161
Cdd:TIGR01425 81 ELCNLVDPGVEAFTPKKGKTCVIMFVGLQGAGKTTTCTKLAYYYKRRGFKPALVCADTFRAGAFDQLKQNATKAGIPFYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 162 SYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVS 241
Cdd:TIGR01425 161 SYEESDPVKIASEGVEKFRKEKFDIIIVDTSGRHKQEKELFEEMQQVREAIKPDSIIFVMDGSIGQAAFGQAKAFKDSVE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 242 VGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVE 321
Cdd:TIGR01425 241 VGSVIITKLDGHAKGGGALSAVAATKSPIIFIGTGEHVDEFEIFDAEPFVSKLLGMGDLKGLIDKVQDLALNDEEKTLIE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 322 NLSQGNFTLRSMYDQFQCSLRI-PLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNpKIF--NES 398
Cdd:TIGR01425 321 HLKEGTFTLRDWYEQFQNLLKMgPLGNIMSMIPGLSHPMMSKGNEEETSAKIKVFMTIMDSMTDRELDSTA-KTMlkDPS 399
|
410 420
....*....|....*....|....*...
gi 18394225 399 RIMRIARGSGRLVREVMEMLEEYKRIAK 426
Cdd:TIGR01425 400 RIRRVARGSGRDIREVNELLEQYKLFAQ 427
|
|
| PRK00771 |
PRK00771 |
signal recognition particle protein Srp54; Provisional |
6-453 |
1.84e-162 |
|
signal recognition particle protein Srp54; Provisional
Pssm-ID: 179118 [Multi-domain] Cd Length: 437 Bit Score: 466.61 E-value: 1.84e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 6 LGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCR 85
Cdd:PRK00771 1 LGESLRDALKKLAGKSRIDEKTVKEVVKDIQRALLQADVNVKLVKELSKSIKERALEEEPPKGLTPREHVIKIVYEELVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 86 ML-DPGKPAFAPKKakPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYT 164
Cdd:PRK00771 81 LLgEETEPLVLPLK--PQTIMLVGLQGSGKTTTAAKLARYFKKKGLKVGLVAADTYRPAAYDQLKQLAEKIGVPFYGDPD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 165 ESDPVKIAVEGVDRFKKEkcDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGA 244
Cdd:PRK00771 159 NKDAVEIAKEGLEKFKKA--DVIIVDTAGRHALEEDLIEEMKEIKEAVKPDEVLLVIDATIGQQAKNQAKAFHEAVGIGG 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 245 VIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLS 324
Cdd:PRK00771 237 IIITKLDGTAKGGGALSAVAETGAPIKFIGTGEKIDDLERFDPDRFISRLLGMGDLESLLEKVEEALDEEEEEKDVEKMM 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 325 QGNFTLRSMYDQFQCSLRI-PLNQLFSMLPGISAEmMPKGHGEESRVKMKRYMTMMDSMTNKELDspNPKIFNESRIMRI 403
Cdd:PRK00771 317 KGKFTLKDMYKQLEAMNKMgPLKQILQMLPGLGGK-LPDEALEVTEEKLKKYKAIMDSMTEEELE--NPEIINASRIRRI 393
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 18394225 404 ARGSGRLVREVMEMLEEYKRIAKTMKGIKiPKNGDMskvipPQMLKQMGG 453
Cdd:PRK00771 394 ARGSGTTVEDVRELLKYYKMMKKAMKQLK-KGKGKM-----GKLMKQFGF 437
|
|
| SRP54_G |
cd17875 |
GTPase domain of the signal recognition 54 kDa subunit; The signal recognition particle (SRP) ... |
102-294 |
1.59e-137 |
|
GTPase domain of the signal recognition 54 kDa subunit; The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal signal sequences of newly synthesized polypeptides at the ribosome. The SRP-polypeptide complex is then targeted to the membrane by an interaction between SRP and its cognated receptor (SR). In mammals, SRP consists of six protein subunits and a 7SL RNA. One of these subunits is a 54 kd protein (SRP54), which is a GTP-binding protein that interacts with the signal sequence when it emerges from the ribosome. SRP54 is a multidomain protein that consists of an N-terminal domain, followed by a central G (GTPase) domain and a C-terminal M domain.
Pssm-ID: 349784 Cd Length: 193 Bit Score: 393.48 E-value: 1.59e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 102 SVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKK 181
Cdd:cd17875 1 NVIMFVGLQGSGKTTTAAKLAYYYQKKGYKVGLVCADTFRAGAFDQLKQNATKARVPFYGSYTEKDPVKIAKEGVEKFKK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 182 EKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALS 261
Cdd:cd17875 81 EKFDIIIVDTSGRHKQEEELFEEMKQISDAVKPDEVILVIDASIGQAAEDQAKAFKEAVDIGSVIITKLDGHAKGGGALS 160
|
170 180 190
....*....|....*....|....*....|...
gi 18394225 262 AVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRL 294
Cdd:cd17875 161 AVAATGAPIIFIGTGEHIDDLEPFDPKRFVSRL 193
|
|
| Ffh |
COG0541 |
Signal recognition particle GTPase [Intracellular trafficking, secretion, and vesicular ... |
6-426 |
3.40e-132 |
|
Signal recognition particle GTPase [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440307 [Multi-domain] Cd Length: 423 Bit Score: 388.61 E-value: 3.40e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 6 LGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIK-KIVN---LDDLAAGhnkrliieQAIFK 81
Cdd:COG0541 5 LSERLQGAFKKLRGKGRLTEENIKEALREVRRALLEADVNLKVVKDFIERVKeRALGeevLKSLTPG--------QQVIK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 82 ----ELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKI 157
Cdd:COG0541 77 ivhdELVELLGGENEELNLAKKPPTVIMMVGLQGSGKTTTAAKLAKYLKKKGKKPLLVAADVYRPAAIEQLKTLGEQIGV 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 158 PFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFK 237
Cdd:COG0541 157 PVFPEEDGKDPVDIAKRALEYAKKNGYDVVIVDTAGRLHIDEELMDELKAIKAAVNPDETLLVVDAMTGQDAVNVAKAFN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 238 ETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQN 317
Cdd:COG0541 237 EALGLTGVILTKLDGDARGGAALSIRAVTGKPIKFIGTGEKLDDLEPFHPDRMASRILGMGDVLSLIEKAQEAIDEEEAE 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 318 ELVENLSQGNFTLRSMYDQFQcslRI----PLNQLFSMLPGISAEMMPKGHGEESRvKMKRYMTMMDSMTNKELDspNPK 393
Cdd:COG0541 317 KLAKKLKKGKFDLEDFLEQLQ---QMkkmgPLKKLLGMLPGMGKLKQLKDLDIDEK-ELKRIEAIINSMTPEERR--NPD 390
|
410 420 430
....*....|....*....|....*....|...
gi 18394225 394 IFNESRIMRIARGSGRLVREVMEMLEEYKRIAK 426
Cdd:COG0541 391 IINGSRKRRIAKGSGTTVQDVNRLLKQFEQMKK 423
|
|
| SRP54 |
pfam00448 |
SRP54-type protein, GTPase domain; This family includes relatives of the G-domain of the SRP54 ... |
102-294 |
1.84e-106 |
|
SRP54-type protein, GTPase domain; This family includes relatives of the G-domain of the SRP54 family of proteins.
Pssm-ID: 459814 [Multi-domain] Cd Length: 193 Bit Score: 314.48 E-value: 1.84e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 102 SVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKK 181
Cdd:pfam00448 1 NVILLVGLQGSGKTTTIAKLAAYLKKKGKKVLLVAADTFRAAAIEQLKQLAEKLGVPVFGSKTGADPAAVAFDAVEKAKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 182 EKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALS 261
Cdd:pfam00448 81 ENYDVVLVDTAGRLQNDKNLMDELKKIKRVVAPDEVLLVLDATTGQNAVNQAKAFNEAVGITGVILTKLDGDAKGGAALS 160
|
170 180 190
....*....|....*....|....*....|...
gi 18394225 262 AVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRL 294
Cdd:pfam00448 161 IVAETGKPIKFIGVGEKIDDLEPFDPERFVSRL 193
|
|
| SRP54 |
smart00962 |
SRP54-type protein, GTPase domain; This entry represents the GTPase domain of the 54 kDa SRP54 ... |
101-296 |
2.62e-91 |
|
SRP54-type protein, GTPase domain; This entry represents the GTPase domain of the 54 kDa SRP54 component, a GTP-binding protein that interacts with the signal sequence when it emerges from the ribosome. SRP54 of the signal recognition particle has a three-domain structure: an N-terminal helical bundle domain, a GTPase domain, and the M-domain that binds the 7s RNA and also binds the signal sequence. The extreme C-terminal region is glycine-rich and lower in complexity and poorly conserved between species. The GTPase domain is evolutionary related to P-loop NTPase domains found in a variety of other proteins.
Pssm-ID: 214940 Cd Length: 197 Bit Score: 275.83 E-value: 2.62e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 101 PSVVMFVGLQGAGKTTTCTKYAYYHQKKG-YKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRF 179
Cdd:smart00962 1 PGVILLVGPNGVGKTTTIAKLAARLKLKGgKKVLLVAADTFRAAAVEQLKTYAEILGVVPVAGGEGADPVAVAKDAVELA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 180 KKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGA 259
Cdd:smart00962 81 KARGYDVVLIDTAGRLHNDENLMEELKKIKRVIKPDEVLLVSDATTGQDAVEQAKAFNEALGLTGIILTKLDGTAKGGAA 160
|
170 180 190
....*....|....*....|....*....|....*..
gi 18394225 260 LSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLG 296
Cdd:smart00962 161 LSIAAETGLPIKFIGTGEKVPDLEPFDPERFVSRLLG 197
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SRP54_euk |
TIGR01425 |
signal recognition particle protein SRP54; This model represents examples from the eukaryotic ... |
2-426 |
0e+00 |
|
signal recognition particle protein SRP54; This model represents examples from the eukaryotic cytosol of the signal recognition particle protein component, SRP54. This GTP-binding protein is a component of the eukaryotic signal recognition particle, along with several other protein subunits and a 7S RNA. Some species, including Arabidopsis, have several closely related forms. The extreme C-terminal region is glycine-rich and lower in complexity, poorly conserved between species, and excluded from this model.
Pssm-ID: 273615 [Multi-domain] Cd Length: 428 Bit Score: 659.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 2 VLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFK 81
Cdd:TIGR01425 1 VLAQLGSSLVTALRSMSSATVIDEEVINTMLKEICTALLESDVNPKLVRQMRNNIKKKINLEDIASGINKRKLIQDAVFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 82 ELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYG 161
Cdd:TIGR01425 81 ELCNLVDPGVEAFTPKKGKTCVIMFVGLQGAGKTTTCTKLAYYYKRRGFKPALVCADTFRAGAFDQLKQNATKAGIPFYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 162 SYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVS 241
Cdd:TIGR01425 161 SYEESDPVKIASEGVEKFRKEKFDIIIVDTSGRHKQEKELFEEMQQVREAIKPDSIIFVMDGSIGQAAFGQAKAFKDSVE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 242 VGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVE 321
Cdd:TIGR01425 241 VGSVIITKLDGHAKGGGALSAVAATKSPIIFIGTGEHVDEFEIFDAEPFVSKLLGMGDLKGLIDKVQDLALNDEEKTLIE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 322 NLSQGNFTLRSMYDQFQCSLRI-PLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNpKIF--NES 398
Cdd:TIGR01425 321 HLKEGTFTLRDWYEQFQNLLKMgPLGNIMSMIPGLSHPMMSKGNEEETSAKIKVFMTIMDSMTDRELDSTA-KTMlkDPS 399
|
410 420
....*....|....*....|....*...
gi 18394225 399 RIMRIARGSGRLVREVMEMLEEYKRIAK 426
Cdd:TIGR01425 400 RIRRVARGSGRDIREVNELLEQYKLFAQ 427
|
|
| PRK00771 |
PRK00771 |
signal recognition particle protein Srp54; Provisional |
6-453 |
1.84e-162 |
|
signal recognition particle protein Srp54; Provisional
Pssm-ID: 179118 [Multi-domain] Cd Length: 437 Bit Score: 466.61 E-value: 1.84e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 6 LGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCR 85
Cdd:PRK00771 1 LGESLRDALKKLAGKSRIDEKTVKEVVKDIQRALLQADVNVKLVKELSKSIKERALEEEPPKGLTPREHVIKIVYEELVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 86 ML-DPGKPAFAPKKakPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYT 164
Cdd:PRK00771 81 LLgEETEPLVLPLK--PQTIMLVGLQGSGKTTTAAKLARYFKKKGLKVGLVAADTYRPAAYDQLKQLAEKIGVPFYGDPD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 165 ESDPVKIAVEGVDRFKKEkcDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGA 244
Cdd:PRK00771 159 NKDAVEIAKEGLEKFKKA--DVIIVDTAGRHALEEDLIEEMKEIKEAVKPDEVLLVIDATIGQQAKNQAKAFHEAVGIGG 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 245 VIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLS 324
Cdd:PRK00771 237 IIITKLDGTAKGGGALSAVAETGAPIKFIGTGEKIDDLERFDPDRFISRLLGMGDLESLLEKVEEALDEEEEEKDVEKMM 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 325 QGNFTLRSMYDQFQCSLRI-PLNQLFSMLPGISAEmMPKGHGEESRVKMKRYMTMMDSMTNKELDspNPKIFNESRIMRI 403
Cdd:PRK00771 317 KGKFTLKDMYKQLEAMNKMgPLKQILQMLPGLGGK-LPDEALEVTEEKLKKYKAIMDSMTEEELE--NPEIINASRIRRI 393
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 18394225 404 ARGSGRLVREVMEMLEEYKRIAKTMKGIKiPKNGDMskvipPQMLKQMGG 453
Cdd:PRK00771 394 ARGSGTTVEDVRELLKYYKMMKKAMKQLK-KGKGKM-----GKLMKQFGF 437
|
|
| SRP54_G |
cd17875 |
GTPase domain of the signal recognition 54 kDa subunit; The signal recognition particle (SRP) ... |
102-294 |
1.59e-137 |
|
GTPase domain of the signal recognition 54 kDa subunit; The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal signal sequences of newly synthesized polypeptides at the ribosome. The SRP-polypeptide complex is then targeted to the membrane by an interaction between SRP and its cognated receptor (SR). In mammals, SRP consists of six protein subunits and a 7SL RNA. One of these subunits is a 54 kd protein (SRP54), which is a GTP-binding protein that interacts with the signal sequence when it emerges from the ribosome. SRP54 is a multidomain protein that consists of an N-terminal domain, followed by a central G (GTPase) domain and a C-terminal M domain.
Pssm-ID: 349784 Cd Length: 193 Bit Score: 393.48 E-value: 1.59e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 102 SVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKK 181
Cdd:cd17875 1 NVIMFVGLQGSGKTTTAAKLAYYYQKKGYKVGLVCADTFRAGAFDQLKQNATKARVPFYGSYTEKDPVKIAKEGVEKFKK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 182 EKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALS 261
Cdd:cd17875 81 EKFDIIIVDTSGRHKQEEELFEEMKQISDAVKPDEVILVIDASIGQAAEDQAKAFKEAVDIGSVIITKLDGHAKGGGALS 160
|
170 180 190
....*....|....*....|....*....|...
gi 18394225 262 AVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRL 294
Cdd:cd17875 161 AVAATGAPIIFIGTGEHIDDLEPFDPKRFVSRL 193
|
|
| Ffh |
COG0541 |
Signal recognition particle GTPase [Intracellular trafficking, secretion, and vesicular ... |
6-426 |
3.40e-132 |
|
Signal recognition particle GTPase [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440307 [Multi-domain] Cd Length: 423 Bit Score: 388.61 E-value: 3.40e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 6 LGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIK-KIVN---LDDLAAGhnkrliieQAIFK 81
Cdd:COG0541 5 LSERLQGAFKKLRGKGRLTEENIKEALREVRRALLEADVNLKVVKDFIERVKeRALGeevLKSLTPG--------QQVIK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 82 ----ELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKI 157
Cdd:COG0541 77 ivhdELVELLGGENEELNLAKKPPTVIMMVGLQGSGKTTTAAKLAKYLKKKGKKPLLVAADVYRPAAIEQLKTLGEQIGV 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 158 PFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFK 237
Cdd:COG0541 157 PVFPEEDGKDPVDIAKRALEYAKKNGYDVVIVDTAGRLHIDEELMDELKAIKAAVNPDETLLVVDAMTGQDAVNVAKAFN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 238 ETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQN 317
Cdd:COG0541 237 EALGLTGVILTKLDGDARGGAALSIRAVTGKPIKFIGTGEKLDDLEPFHPDRMASRILGMGDVLSLIEKAQEAIDEEEAE 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 318 ELVENLSQGNFTLRSMYDQFQcslRI----PLNQLFSMLPGISAEMMPKGHGEESRvKMKRYMTMMDSMTNKELDspNPK 393
Cdd:COG0541 317 KLAKKLKKGKFDLEDFLEQLQ---QMkkmgPLKKLLGMLPGMGKLKQLKDLDIDEK-ELKRIEAIINSMTPEERR--NPD 390
|
410 420 430
....*....|....*....|....*....|...
gi 18394225 394 IFNESRIMRIARGSGRLVREVMEMLEEYKRIAK 426
Cdd:COG0541 391 IINGSRKRRIAKGSGTTVQDVNRLLKQFEQMKK 423
|
|
| SRP54 |
pfam00448 |
SRP54-type protein, GTPase domain; This family includes relatives of the G-domain of the SRP54 ... |
102-294 |
1.84e-106 |
|
SRP54-type protein, GTPase domain; This family includes relatives of the G-domain of the SRP54 family of proteins.
Pssm-ID: 459814 [Multi-domain] Cd Length: 193 Bit Score: 314.48 E-value: 1.84e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 102 SVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKK 181
Cdd:pfam00448 1 NVILLVGLQGSGKTTTIAKLAAYLKKKGKKVLLVAADTFRAAAIEQLKQLAEKLGVPVFGSKTGADPAAVAFDAVEKAKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 182 EKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALS 261
Cdd:pfam00448 81 ENYDVVLVDTAGRLQNDKNLMDELKKIKRVVAPDEVLLVLDATTGQNAVNQAKAFNEAVGITGVILTKLDGDAKGGAALS 160
|
170 180 190
....*....|....*....|....*....|...
gi 18394225 262 AVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRL 294
Cdd:pfam00448 161 IVAETGKPIKFIGVGEKIDDLEPFDPERFVSRL 193
|
|
| ffh |
TIGR00959 |
signal recognition particle protein; This model represents Ffh (Fifty-Four Homolog), the ... |
6-430 |
6.75e-102 |
|
signal recognition particle protein; This model represents Ffh (Fifty-Four Homolog), the protein component that forms the bacterial (and organellar) signal recognition particle together with a 4.5S RNA. Ffh is a GTPase homologous to eukaryotic SRP54 and also to the GTPase FtsY (TIGR00064) that is the receptor for the signal recognition particle. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273364 [Multi-domain] Cd Length: 428 Bit Score: 311.53 E-value: 6.75e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 6 LGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIK-KIVNLDDLAAGHNKRLIIeQAIFKELC 84
Cdd:TIGR00959 4 LSERLQRIFKKLSGRGTITEKNIKEALREIRLALLEADVNLQVVKDFIKKVKeKALGQEVLKSLSPGQQFI-KIVHEELV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 85 RMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKK-GYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSY 163
Cdd:TIGR00959 83 AILGGENAELNLAKKPPTVILMVGLQGSGKTTTCGKLAYYLKKKqGKKVLLVACDLYRPAAIEQLKVLGQQVGVPVFALG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 164 TESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVG 243
Cdd:TIGR00959 163 KGQSPVEIARRALEYAKENGFDVVIVDTAGRLQIDEELMEELAAIKEILNPDEILLVVDAMTGQDAVNTAKTFNERLGLT 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 244 AVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENL 323
Cdd:TIGR00959 243 GVVLTKLDGDARGGAALSVRSVTGKPIKFIGVGEKIDDLEPFHPERMASRILGMGDILSLVEKAQEVVDEEEAKKLAEKM 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 324 SQGNFTLRSMYDQFQCSLRI-PLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDspNPKIFNESRIMR 402
Cdd:TIGR00959 323 KKGQFDLEDFLEQLRQIKKMgPLSSLLKMIPGMGGVKPSLSDADLDEKQFKRIEAIISSMTPEERR--NPKILNPSRRKR 400
|
410 420
....*....|....*....|....*...
gi 18394225 403 IARGSGRLVREVMEMLEEYKRIAKTMKG 430
Cdd:TIGR00959 401 IAAGSGTTVQDVNKLIKRFEQMKKMMKK 428
|
|
| SRP54 |
smart00962 |
SRP54-type protein, GTPase domain; This entry represents the GTPase domain of the 54 kDa SRP54 ... |
101-296 |
2.62e-91 |
|
SRP54-type protein, GTPase domain; This entry represents the GTPase domain of the 54 kDa SRP54 component, a GTP-binding protein that interacts with the signal sequence when it emerges from the ribosome. SRP54 of the signal recognition particle has a three-domain structure: an N-terminal helical bundle domain, a GTPase domain, and the M-domain that binds the 7s RNA and also binds the signal sequence. The extreme C-terminal region is glycine-rich and lower in complexity and poorly conserved between species. The GTPase domain is evolutionary related to P-loop NTPase domains found in a variety of other proteins.
Pssm-ID: 214940 Cd Length: 197 Bit Score: 275.83 E-value: 2.62e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 101 PSVVMFVGLQGAGKTTTCTKYAYYHQKKG-YKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRF 179
Cdd:smart00962 1 PGVILLVGPNGVGKTTTIAKLAARLKLKGgKKVLLVAADTFRAAAVEQLKTYAEILGVVPVAGGEGADPVAVAKDAVELA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 180 KKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGA 259
Cdd:smart00962 81 KARGYDVVLIDTAGRLHNDENLMEELKKIKRVIKPDEVLLVSDATTGQDAVEQAKAFNEALGLTGIILTKLDGTAKGGAA 160
|
170 180 190
....*....|....*....|....*....|....*..
gi 18394225 260 LSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLG 296
Cdd:smart00962 161 LSIAAETGLPIKFIGTGEKVPDLEPFDPERFVSRLLG 197
|
|
| SRP_G_like |
cd03115 |
GTPase domain similar to the signal recognition particle subunit 54; The signal recognition ... |
103-294 |
2.27e-86 |
|
GTPase domain similar to the signal recognition particle subunit 54; The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal signal sequences of newly synthesized polypeptides at the ribosome. The SRP-polypeptide complex is then targeted to the membrane by an interaction between SRP and its cognate receptor (SR). In mammals, SRP consists of six protein subunits and a 7SL RNA. One of these subunits is a 54 kd protein (SRP54), which is a GTP-binding protein that interacts with the signal sequence when it emerges from the ribosome. SRP54 is a multidomain protein that consists of an N-terminal domain, followed by a central G (GTPase) domain and a C-terminal M domain.
Pssm-ID: 349769 [Multi-domain] Cd Length: 193 Bit Score: 263.08 E-value: 2.27e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 103 VVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKE 182
Cdd:cd03115 2 VILLVGLQGSGKTTTLAKLARYYQEKGKKVLLIAADTFRAAAVEQLKTLAEKLGVPVFESYTGTDPASIAQEAVEKAKLE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 183 KCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSA 262
Cdd:cd03115 82 GYDVLLVDTAGRLQKDEPLMEELKKVKEVESPDEVLLVLDATTGQEALSQAKAFNEAVGLTGVILTKLDGTAKGGAALSI 161
|
170 180 190
....*....|....*....|....*....|..
gi 18394225 263 VAATKSPVIFIGTGEHMDEFEVFDVKPFVSRL 294
Cdd:cd03115 162 VAETKKPIKFIGVGEKPEDLEPFDPERFVSAL 193
|
|
| FtsY |
COG0552 |
Signal recognition particle GTPase FtsY [Intracellular trafficking, secretion, and vesicular ... |
6-296 |
1.40e-70 |
|
Signal recognition particle GTPase FtsY [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440318 [Multi-domain] Cd Length: 303 Bit Score: 226.44 E-value: 1.40e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 6 LGGRITRAIQQMNnvtIIDEkvlnDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNkrliIEQAIFKELCR 85
Cdd:COG0552 16 LGEKLKSLFSGKK---KIDE----DLLEELEELLIEADVGVETTEEIIEELRERVKRKKLKDPEE----LKEALKEELLE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 86 MLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTE 165
Cdd:COG0552 85 ILDPVDKPLAIEEKKPFVILVVGVNGVGKTTTIGKLAHRLKAEGKSVLLAAGDTFRAAAIEQLEVWGERVGVPVIAQKEG 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 166 SDPVKIAVEGVDRFKKEKCDLIIVDTSGR-HKQaASLFEE---MRQVAE---ATEPDLVIFVMDSSIGQAAFEQAEAFKE 238
Cdd:COG0552 165 ADPAAVAFDAIQAAKARGADVVIIDTAGRlHNK-KNLMEElkkIKRVIKkldPDAPHEVLLVLDATTGQNALSQAKVFNE 243
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 18394225 239 TVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLG 296
Cdd:COG0552 244 AVGVTGIVLTKLDGTAKGGVVLAIADELGIPIKFIGVGEGIDDLRPFDAEEFVDALFG 301
|
|
| PRK14974 |
PRK14974 |
signal recognition particle-docking protein FtsY; |
19-296 |
1.01e-67 |
|
signal recognition particle-docking protein FtsY;
Pssm-ID: 237875 [Multi-domain] Cd Length: 336 Bit Score: 220.23 E-value: 1.01e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 19 NVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGK----PAF 94
Cdd:PRK14974 54 KITEIKEKDIEDLLEELELELLESDVALEVAEEILESLKEKLVGKKVKRGEDVEEIVKNALKEALLEVLSVGDlfdlIEE 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 95 APKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVE 174
Cdd:PRK14974 134 IKSKGKPVVIVFVGVNGTGKTTTIAKLAYYLKKNGFSVVIAAGDTFRAGAIEQLEEHAERLGVKVIKHKYGADPAAVAYD 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 175 GVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHA 254
Cdd:PRK14974 214 AIEHAKARGIDVVLIDTAGRMHTDANLMDELKKIVRVTKPDLVIFVGDALAGNDAVEQAREFNEAVGIDGVILTKVDADA 293
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 18394225 255 KGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLG 296
Cdd:PRK14974 294 KGGAALSIAYVIGKPILFLGVGQGYDDLIPFDPDWFVDKLLG 335
|
|
| ftsY |
TIGR00064 |
signal recognition particle-docking protein FtsY; There is a weak division between FtsY and ... |
26-295 |
3.65e-66 |
|
signal recognition particle-docking protein FtsY; There is a weak division between FtsY and SRP54; both are GTPases. In E.coli, ftsY is an essential gene located in an operon with cell division genes ftsE and ftsX, but its apparent function is as the signal recognition particle docking protein. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 272883 [Multi-domain] Cd Length: 277 Bit Score: 214.04 E-value: 3.65e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 26 KVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPG-KPAFAPKKAKPSVV 104
Cdd:TIGR00064 1 KDDEDFFEELEEILLESDVGYEVVEKIIEALKKELKGKKVKDAEKLKEILKEYLKEILKEDLLKNtDLELIVEENKPNVI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 105 MFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKC 184
Cdd:TIGR00064 81 LFVGVNGVGKTTTIAKLANKLKKQGKSVLLAAGDTFRAAAIEQLEEWAKRLGVDVIKQKEGADPAAVAFDAIQKAKARNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 185 DLIIVDTSGRHKQAASLFEEMRQV------AEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGG 258
Cdd:TIGR00064 161 DVVLIDTAGRLQNKVNLMDELKKIkrvikkVDKDAPDEVLLVLDATTGQNALEQAKVFNEAVGLTGIILTKLDGTAKGGI 240
|
250 260 270
....*....|....*....|....*....|....*..
gi 18394225 259 ALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLL 295
Cdd:TIGR00064 241 ILSIAYELKLPIKFIGVGEKIDDLAPFDADWFVEALF 277
|
|
| PRK10416 |
PRK10416 |
signal recognition particle-docking protein FtsY; Provisional |
23-297 |
1.97e-65 |
|
signal recognition particle-docking protein FtsY; Provisional
Pssm-ID: 236686 [Multi-domain] Cd Length: 318 Bit Score: 213.42 E-value: 1.97e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 23 IDEkvlnDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLaagHNKRLIIEqAIFKELCRMLDPGKPAFAPKKAKPS 102
Cdd:PRK10416 44 IDE----DLLEELEELLIEADVGVETTEEIIEELRERVKRKNL---KDPEELKE-LLKEELAEILEPVEKPLNIEEKKPF 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 103 VVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKE 182
Cdd:PRK10416 116 VILVVGVNGVGKTTTIGKLAHKYKAQGKKVLLAAGDTFRAAAIEQLQVWGERVGVPVIAQKEGADPASVAFDAIQAAKAR 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 183 KCDLIIVDTSGR-HKQAAsLFEE---MRQV---AEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAK 255
Cdd:PRK10416 196 GIDVLIIDTAGRlHNKTN-LMEElkkIKRVikkADPDAPHEVLLVLDATTGQNALSQAKAFHEAVGLTGIILTKLDGTAK 274
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 18394225 256 GGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGK 297
Cdd:PRK10416 275 GGVVFAIADELGIPIKFIGVGEGIDDLQPFDAEEFVDALLGG 316
|
|
| SRP_G |
cd18539 |
GTPase domain of signal recognition particle protein; The signal recognition particle (SRP) ... |
102-294 |
6.82e-62 |
|
GTPase domain of signal recognition particle protein; The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal signal sequences of newly synthesized polypeptides at the ribosome. The SRP-polypeptide complex is then targeted to the membrane by an interaction between SRP and its cognated receptor (SR). In mammals, SRP consists of six protein subunits and a 7SL RNA. One of these subunits is a 54 kd protein (SRP54), which is a GTP-binding protein that interacts with the signal sequence when it emerges from the ribosome. SRP54 is a multidomain protein that consists of an N-terminal domain, followed by a central G (GTPase) domain and a C-terminal M domain.
Pssm-ID: 349786 Cd Length: 193 Bit Score: 200.13 E-value: 6.82e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 102 SVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKK 181
Cdd:cd18539 1 TVILLVGLQGSGKTTTAAKLALYLKKKGKKVLLVAADVYRPAAIEQLQTLGEQVGVPVFESGDGQSPVDIAKRALEKAKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 182 EKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALS 261
Cdd:cd18539 81 EGFDVVIVDTAGRLHIDEELMDELKEIKEVLNPDEVLLVVDAMTGQDAVNVAKAFNERLGLTGVVLTKLDGDARGGAALS 160
|
170 180 190
....*....|....*....|....*....|...
gi 18394225 262 AVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRL 294
Cdd:cd18539 161 IRHVTGKPIKFIGVGEKIEDLEPFHPDRMASRI 193
|
|
| FtsY |
cd17874 |
signal recognition particle receptor FtsY; FtsY, the bacterial signal-recognition particle ... |
103-294 |
4.22e-55 |
|
signal recognition particle receptor FtsY; FtsY, the bacterial signal-recognition particle (SRP) receptor (SR), is homologous to the SRP receptor alpha-subunit (SRalpha) of the eukaryotic SR. It interacts with the signal-recognition particle (SRP) and is required for the co-translational membrane targeting of proteins.
Pssm-ID: 349783 Cd Length: 199 Bit Score: 182.77 E-value: 4.22e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 103 VVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKE 182
Cdd:cd17874 2 VILFVGVNGVGKTTTIGKLAHYLKNQGKKVVLAAGDTFRAAAVEQLEEWAERLGVPVISQNEGADPAAVAFDAIQAAKAR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 183 KCDLIIVDTSGRHKQAASLFEEMRQV------AEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKG 256
Cdd:cd17874 82 GIDVVLIDTAGRLHTKKNLMEELKKIkrvikkKDPEAPHEVLLVLDATTGQNALEQAKEFNEAVGLTGIILTKLDGTAKG 161
|
170 180 190
....*....|....*....|....*....|....*...
gi 18394225 257 GGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRL 294
Cdd:cd17874 162 GIVLSIADELKIPVKFVGVGEGIDDLRPFDPEAFVEAL 199
|
|
| FlhF |
COG1419 |
Flagellar biosynthesis GTPase FlhF [Cell motility]; |
2-296 |
5.22e-36 |
|
Flagellar biosynthesis GTPase FlhF [Cell motility];
Pssm-ID: 441029 [Multi-domain] Cd Length: 361 Bit Score: 136.53 E-value: 5.22e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 2 VLAELGgRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDlaaghnkrliIEQAIFK 81
Cdd:COG1419 79 LRRELA-ELKELLEEQLSGLAGESARLPPELAELLERLLEAGVSPELARELLEKLPEDLSAEE----------AWRALLE 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 82 ELCRMLD-PGKPAFAPKKakpsVVMFVGLQGAGKTTTCTKYA-YYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPF 159
Cdd:COG1419 148 ALARRLPvAEDPLLDEGG----VIALVGPTGVGKTTTIAKLAaRFVLRGKKKVALITTDTYRIGAVEQLKTYARILGVPV 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 160 YGSYTESDpVKIAVEgvdRFKkeKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSI-GQAAFEQAEAFKE 238
Cdd:COG1419 224 EVAYDPEE-LKEALE---RLR--DKDLVLIDTAGRSPRDPELIEELKALLDAGPPIEVYLVLSATTkYEDLKEIVEAFSS 297
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 18394225 239 tVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHM-DEFEVFDVKPFVSRLLG 296
Cdd:COG1419 298 -LGLDGLILTKLDETASLGSILNLLIRTGLPLSYITNGQRVpEDIEVADPERLARLLLG 355
|
|
| SRalpha_C |
cd17876 |
C-terminal domain of signal recognition particle receptor alpha subunit; The ... |
103-294 |
5.07e-33 |
|
C-terminal domain of signal recognition particle receptor alpha subunit; The signal-recognition particle (SRP) receptor (SR) alpha-subunit (SRalpha) of the eukaryotic SR interacts with the signal-recognition particle (SRP) and is essential for the co-translational membrane targeting of proteins.
Pssm-ID: 349785 Cd Length: 204 Bit Score: 124.26 E-value: 5.07e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 103 VVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKE 182
Cdd:cd17876 2 VIVFCGVNGVGKSTNLAKIAYWLLSNGFRVLIAACDTFRSGAVEQLRTHARRLGVELYEKGYGKDPAAVAKEAIKYARDQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 183 KCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGA----------VIITKMDG 252
Cdd:cd17876 82 GFDVVLIDTAGRMQNNEPLMRALAKLIKENNPDLVLFVGEALVGNDAVDQLKKFNQALADYSpsdnprlidgIVLTKFDT 161
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 18394225 253 -HAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRL 294
Cdd:cd17876 162 iDDKVGAALSMVYATGQPIVFVGTGQTYTDLKKLNVKAVVNSL 204
|
|
| SRP_SPB |
pfam02978 |
Signal peptide binding domain; |
328-426 |
1.40e-30 |
|
Signal peptide binding domain;
Pssm-ID: 460771 [Multi-domain] Cd Length: 95 Bit Score: 113.65 E-value: 1.40e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 328 FTLRSMYDQFQCSLRI-PLNQLFSMLPGisaeMMPKGHGEESRVKMKRYMTMMDSMTNKELDspNPKIFNESRIMRIARG 406
Cdd:pfam02978 2 FTLRDFLEQLQQIKKMgPLSKILSMIPG----MGKKDDDIDSEKKLKRIEAIIDSMTPKERD--NPDIINASRKRRIARG 75
|
90 100
....*....|....*....|
gi 18394225 407 SGRLVREVMEMLEEYKRIAK 426
Cdd:pfam02978 76 SGTSVQEVNRLLKQFKQMKK 95
|
|
| FlhF |
cd17873 |
signal-recognition particle GTPase FlhF; FlhF protein is a signal-recognition particle (SRP) ... |
103-294 |
3.41e-28 |
|
signal-recognition particle GTPase FlhF; FlhF protein is a signal-recognition particle (SRP)-type GTPase that is essential for the placement and assembly of polar flagella. It is similar to the 54 kd subunit (SRP54) of the signal recognition particle (SRP) that mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal signal sequences of newly synthesized polypeptides at the ribosome. The SRP-polypeptide complex is then targeted to the membrane by an interaction between SRP and its cognated receptor (SR).
Pssm-ID: 349782 [Multi-domain] Cd Length: 189 Bit Score: 110.33 E-value: 3.41e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 103 VVMFVGLQGAGKTTTCTKYA-YYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDpVKIAVEGVDRfkk 181
Cdd:cd17873 2 VIALVGPTGVGKTTTLAKLAaRYVLKKGKKVALITTDTYRIGAVEQLKTYAEIMGIPVEVAEDPED-LADALERLSD--- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 182 ekCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMdsSIGQAAFEQAEAFK--ETVSVGAVIITKMDGHAKGGGA 259
Cdd:cd17873 78 --RDLILIDTAGRSPRDKEQLEELKELLGAGEDIEVHLVL--SATTKAKDLKEIIErfSPLGYRGLILTKLDETTSLGSV 153
|
170 180 190
....*....|....*....|....*....|....*.
gi 18394225 260 LSAVAATKSPVIFIGTGEHM-DEFEVFDVKPFVSRL 294
Cdd:cd17873 154 LSVLAESQLPVSYVTTGQRVpEDIEVASPLRLARLL 189
|
|
| flhF |
PRK05703 |
flagellar biosynthesis protein FlhF; |
34-296 |
2.50e-25 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235570 [Multi-domain] Cd Length: 424 Bit Score: 107.67 E-value: 2.50e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 34 EITRALLQSDVSFGLVEKMqtnIKKIVNLDDLAAGHNKRLIIEQaifkeLCRMLDPGKPAFAPKKakpSVVMFVGLQGAG 113
Cdd:PRK05703 165 ELYKRLKRSGLSPEIAEKL---LKLLLEHMPPRERTAWRYLLEL-----LANMIPVRVEDILKQG---GVVALVGPTGVG 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 114 KTTTCTK----YAYYHQKKgyKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIavegVDRFKkeKCDLIIV 189
Cdd:PRK05703 234 KTTTLAKlaarYALLYGKK--KVALITLDTYRIGAVEQLKTYAKIMGIPVEVVYDPKELAKA----LEQLR--DCDVILI 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 190 DTSGRHKQAASLFEEMRQVAEATEPDLVIF-VMdSSIGQ-----AAFEQaeaFKEtVSVGAVIITKMDGHAKGGGALSAV 263
Cdd:PRK05703 306 DTAGRSQRDKRLIEELKALIEFSGEPIDVYlVL-SATTKyedlkDIYKH---FSR-LPLDGLIFTKLDETSSLGSILSLL 380
|
250 260 270
....*....|....*....|....*....|....
gi 18394225 264 AATKSPVIFIGTGEHM-DEFEVFDVKPFVSRLLG 296
Cdd:PRK05703 381 IESGLPISYLTNGQRVpDDIKVANPEELVRLLLG 414
|
|
| FlhF |
TIGR03499 |
flagellar biosynthetic protein FlhF; [Cellular processes, Chemotaxis and motility] |
34-193 |
1.03e-17 |
|
flagellar biosynthetic protein FlhF; [Cellular processes, Chemotaxis and motility]
Pssm-ID: 274609 [Multi-domain] Cd Length: 282 Bit Score: 83.15 E-value: 1.03e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 34 EITRALLQSDVSFGLVEKMQTNIKKIVNLDDlaaghnkrliIEQAIFKELCRMLdPGKPAFAPKKAKPSVVMFVGLQGAG 113
Cdd:TIGR03499 138 KLYERLLEAGVSEELARELLEKLPEDADAED----------AWRWLREALEGML-PVKPEEDPILEQGGVIALVGPTGVG 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 114 KTTTCTK----YAYYHQKKgyKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDpvkiAVEGVDRFKkeKCDLIIV 189
Cdd:TIGR03499 207 KTTTLAKlaarFALEHGKK--KVALITTDTYRIGAVEQLKTYAEILGIPVKVARDPKE----LREALDRLR--DKDLILI 278
|
....
gi 18394225 190 DTSG 193
Cdd:TIGR03499 279 DTAG 282
|
|
| PRK12726 |
PRK12726 |
flagellar biosynthesis regulator FlhF; Provisional |
103-281 |
2.04e-13 |
|
flagellar biosynthesis regulator FlhF; Provisional
Pssm-ID: 183704 [Multi-domain] Cd Length: 407 Bit Score: 71.69 E-value: 2.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 103 VVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFygsYTESDPVKIAvEGVDRFKKE 182
Cdd:PRK12726 208 IISLIGQTGVGKTTTLVKLGWQLLKQNRTVGFITTDTFRSGAVEQFQGYADKLDVEL---IVATSPAELE-EAVQYMTYV 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 183 KC-DLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALS 261
Cdd:PRK12726 284 NCvDHILIDTVGRNYLAEESVSEISAYTDVVHPDLTCFTFSSGMKSADVMTILPKLAEIPIDGFIITKMDETTRIGDLYT 363
|
170 180
....*....|....*....|
gi 18394225 262 AVAATKSPVIFIGTGEHMDE 281
Cdd:PRK12726 364 VMQETNLPVLYMTDGQNITE 383
|
|
| flhF |
PRK11889 |
flagellar biosynthesis protein FlhF; |
104-277 |
1.45e-11 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 183360 [Multi-domain] Cd Length: 436 Bit Score: 66.24 E-value: 1.45e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 104 VMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNatkakIPFYGSYTESDPVKIAVE-GVDRFKKE 182
Cdd:PRK11889 244 IALIGPTGVGKTTTLAKMAWQFHGKKKTVGFITTDHSRIGTVQQLQDY-----VKTIGFEVIAVRDEAAMTrALTYFKEE 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 183 -KCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSI-GQAAFEQAEAFKEtVSVGAVIITKMDGHAKGGGAL 260
Cdd:PRK11889 319 aRVDYILIDTAGKNYRASETVEEMIETMGQVEPDYICLTLSASMkSKDMIEIITNFKD-IHIDGIVFTKFDETASSGELL 397
|
170
....*....|....*..
gi 18394225 261 SAVAATKSPVIFIGTGE 277
Cdd:PRK11889 398 KIPAVSSAPIVLMTDGQ 414
|
|
| flhF |
PRK06731 |
flagellar biosynthesis regulator FlhF; Validated |
104-277 |
2.34e-11 |
|
flagellar biosynthesis regulator FlhF; Validated
Pssm-ID: 75717 [Multi-domain] Cd Length: 270 Bit Score: 64.38 E-value: 2.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 104 VMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKiaveGVDRFKKE- 182
Cdd:PRK06731 78 IALIGPTGVGKTTTLAKMAWQFHGKKKTVGFITTDHSRIGTVQQLQDYVKTIGFEVIAVRDEAAMTR----ALTYFKEEa 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 183 KCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSI-GQAAFEQAEAFKEtVSVGAVIITKMDGHAKGGGALS 261
Cdd:PRK06731 154 RVDYILIDTAGKNYRASETVEEMIETMGQVEPDYICLTLSASMkSKDMIEIITNFKD-IHIDGIVFTKFDETASSGELLK 232
|
170
....*....|....*.
gi 18394225 262 AVAATKSPVIFIGTGE 277
Cdd:PRK06731 233 IPAVSSAPIVLMTDGQ 248
|
|
| PRK12724 |
PRK12724 |
flagellar biosynthesis regulator FlhF; Provisional |
39-297 |
2.50e-11 |
|
flagellar biosynthesis regulator FlhF; Provisional
Pssm-ID: 183703 [Multi-domain] Cd Length: 432 Bit Score: 65.37 E-value: 2.50e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 39 LLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNkrlIIEQAIFKELCRM-LDPGKPAFAPKKaKPSVVMFVGLQGAGKTTT 117
Cdd:PRK12724 164 LVREGMSQSYVEEMASKLEERLSPVDQGRNHN---VTERAVTYLEERVsVDSDLFSGTGKN-QRKVVFFVGPTGSGKTTS 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 118 CTKYAY-YHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYgsytesdpvkiAVEGVDRFK----KEKCDLIIVDTS 192
Cdd:PRK12724 240 IAKLAAkYFLHMGKSVSLYTTDNYRIAAIEQLKRYADTMGMPFY-----------PVKDIKKFKetlaRDGSELILIDTA 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 193 GRHKQAASLFEEMRQVAEA-TEPDLV--IFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSP 269
Cdd:PRK12724 309 GYSHRNLEQLERMQSFYSCfGEKDSVenLLVLSSTSSYHHTLTVLKAYESLNYRRILLTKLDEADFLGSFLELADTYSKS 388
|
250 260
....*....|....*....|....*...
gi 18394225 270 VIFIGTGEHMDefevFDVKPFVSRLLGK 297
Cdd:PRK12724 389 FTYLSVGQEVP----FDILNATKNLMAE 412
|
|
| SRP54_N |
pfam02881 |
SRP54-type protein, helical bundle domain; |
6-83 |
3.01e-11 |
|
SRP54-type protein, helical bundle domain;
Pssm-ID: 460734 [Multi-domain] Cd Length: 75 Bit Score: 59.02 E-value: 3.01e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 18394225 6 LGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKK-IVNLDDLaaghNKRLIIEQAIFKEL 83
Cdd:pfam02881 1 LGEKLSSLFKGLRGKGKIDEEDLEEALKELEEALLEADVGVEVVKKIIERLREkAVGEKKL----KPPQEVKKILKEEL 75
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
100-208 |
4.59e-09 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 55.07 E-value: 4.59e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 100 KPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQnatkakIPFYGSYTESDPVKIAVEGVDRF 179
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLL------IIVGGKKASGSGELRLRLALALA 74
|
90 100
....*....|....*....|....*....
gi 18394225 180 KKEKCDLIIVDTSGRHKQAASLFEEMRQV 208
Cdd:smart00382 75 RKLKPDVLILDEITSLLDAEQEALLLLLE 103
|
|
| SRP54_N |
smart00963 |
SRP54-type protein, helical bundle domain; This entry represents the N-terminal helical bundle ... |
10-87 |
7.63e-09 |
|
SRP54-type protein, helical bundle domain; This entry represents the N-terminal helical bundle domain of the 54 kDa SRP54 component, a GTP-binding protein that interacts with the signal sequence when it emerges from the ribosome. SRP54 of the signal recognition particle has a three-domain structure: an N-terminal helical bundle domain, a GTPase domain, and the M-domain that binds the 7s RNA and also binds the signal sequence. The extreme C-terminal region is glycine-rich and lower in complexity and poorly conserved between species.
Pssm-ID: 214941 [Multi-domain] Cd Length: 77 Bit Score: 52.17 E-value: 7.63e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 18394225 10 ITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEqAIFKELCRML 87
Cdd:smart00963 1 LSKALGKLLGELFLTEKDDEELLEELEEALLEADVGVEVVKEIIERVKEKAKGEVLKGLTPKQEVKK-ILKEELVKIL 77
|
|
| PRK12723 |
PRK12723 |
flagellar biosynthesis regulator FlhF; Provisional |
25-297 |
1.86e-08 |
|
flagellar biosynthesis regulator FlhF; Provisional
Pssm-ID: 183702 [Multi-domain] Cd Length: 388 Bit Score: 56.45 E-value: 1.86e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 25 EKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLaaghNKRLIIEQAIFKELCRMLDPGKPAFApkKAKPSVV 104
Cdd:PRK12723 104 EEINHPTILKIEDILRENDFSESYIKDINEFIKKEFSLSDL----DDYDKVRDSVIIYIAKTIKCSGSIID--NLKKRVF 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 105 MFVGLQGAGKTTTCTKYAYYH----QKKGYKAALVCADTFRAGAfdqlkqnatKAKIPFYGsytesDPVKIAVEGVDRFK 180
Cdd:PRK12723 178 ILVGPTGVGKTTTIAKLAAIYginsDDKSLNIKIITIDNYRIGA---------KKQIQTYG-----DIMGIPVKAIESFK 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 181 KEK--------CDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAA-----FEQAEAFketvSVGAVII 247
Cdd:PRK12723 244 DLKeeitqskdFDLVLVDTIGKSPKDFMKLAEMKELLNACGRDAEFHLAVSSTTKTSdvkeiFHQFSPF----SYKTVIF 319
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 18394225 248 TKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDE----------------FEVFDVKPFVSRLLGK 297
Cdd:PRK12723 320 TKLDETTCVGNLISLIYEMRKEVSYVTDGQIVPHnisiaepltfikkingYRISDDAEFIRKLKSK 385
|
|
| PRK12727 |
PRK12727 |
flagellar biosynthesis protein FlhF; |
103-281 |
1.02e-07 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 237182 [Multi-domain] Cd Length: 559 Bit Score: 54.23 E-value: 1.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 103 VVMFVGLQGAGKTTTCTKYA--YYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYgsytESDPVKIAVEGVDRFK 180
Cdd:PRK12727 352 VIALVGPTGAGKTTTIAKLAqrFAAQHAPRDVALVTTDTQRVGGREQLHSYGRQLGIAVH----EADSAESLLDLLERLR 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 181 KEKcdLIIVDTSG---RHKQAASLFEEMRQVAEATEpdLVIFVMDSSIGQAAfEQAEAFKETVSVGaVIITKMDGHAKGG 257
Cdd:PRK12727 428 DYK--LVLIDTAGmgqRDRALAAQLNWLRAARQVTS--LLVLPANAHFSDLD-EVVRRFAHAKPQG-VVLTKLDETGRFG 501
|
170 180
....*....|....*....|....
gi 18394225 258 GALSAVAATKSPVIFIGTGEHMDE 281
Cdd:PRK12727 502 SALSVVVDHQMPITWVTDGQRVPD 525
|
|
| flhF |
PRK14723 |
flagellar biosynthesis regulator FlhF; Provisional |
103-295 |
1.09e-07 |
|
flagellar biosynthesis regulator FlhF; Provisional
Pssm-ID: 237802 [Multi-domain] Cd Length: 767 Bit Score: 54.42 E-value: 1.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 103 VVMFVGLQGAGKTTTCTKYA--YYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGsytesdpVKIAVEgvDRFK 180
Cdd:PRK14723 187 VLALVGPTGVGKTTTTAKLAarCVAREGADQLALLTTDSFRIGALEQLRIYGRILGVPVHA-------VKDAAD--LRFA 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 181 ----KEKcDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMD-SSIGQAAFEQAEAFKETVS--VGAVIITKMDGH 253
Cdd:PRK14723 258 laalGDK-HLVLIDTVGMSQRDRNVSEQIAMLCGVGRPVRRLLLLNaASHGDTLNEVVHAYRHGAGedVDGCIITKLDEA 336
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 18394225 254 AKGGGALSAVAATKSPVIFIGTGEHMDE-FEVFDVKPFVSRLL 295
Cdd:PRK14723 337 THLGPALDTVIRHRLPVHYVSTGQKVPEhLELAQADELVDRAF 379
|
|
| flhF |
PRK14722 |
flagellar biosynthesis regulator FlhF; Provisional |
103-291 |
8.82e-07 |
|
flagellar biosynthesis regulator FlhF; Provisional
Pssm-ID: 173185 [Multi-domain] Cd Length: 374 Bit Score: 50.88 E-value: 8.82e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 103 VVMFVGLQGAGKTTTCTKYAYYHQKK--GYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDpVKIAVEGVdRFK 180
Cdd:PRK14722 139 VFALMGPTGVGKTTTTAKLAARCVMRfgASKVALLTTDSYRIGGHEQLRIFGKILGVPVHAVKDGGD-LQLALAEL-RNK 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 181 KekcdLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMD-SSIGQAAFEQAEAFKETV--------SVGAVIITKMD 251
Cdd:PRK14722 217 H----MVLIDTIGMSQRDRTVSDQIAMLHGADTPVQRLLLLNaTSHGDTLNEVVQAYRSAAgqpkaalpDLAGCILTKLD 292
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 18394225 252 GHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFV 291
Cdd:PRK14722 293 EASNLGGVLDTVIRYKLPVHYVSTGQKVPENLYVATKKFL 332
|
|
| Grc3 |
COG1341 |
Polynucleotide 5'-kinase, involved in rRNA processing [Translation, ribosomal structure and ... |
98-220 |
4.28e-05 |
|
Polynucleotide 5'-kinase, involved in rRNA processing [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440952 Cd Length: 353 Bit Score: 45.40 E-value: 4.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 98 KAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCAD--------------TFRAGAFDQLKQnATKAKIPFYGSY 163
Cdd:COG1341 32 SSGPGRIMVLGPVDSGKSTLTTLLANKLLAEGLKVAIIDADvgqsdlgppttvslGLVREPVLSLSE-LKAEKLRFVGSI 110
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 18394225 164 TESDPVKIAVEG----VDRFKKEKCDLIIVDTSGRHKQAASLfEEMRQVAEATEPDLVIFV 220
Cdd:COG1341 111 SPSGHLLRIVAGvkrlVERAKERGADRIVIDTDGWVRGPAAR-EYKAALIEALKPDLIVVL 170
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
102-223 |
2.00e-04 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 42.60 E-value: 2.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 102 SVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVcadTFRAGAfDQLKQNATKAKIPFyGSYTESDPVKIavegVDrfkk 181
Cdd:COG0467 21 SSTLLSGPPGTGKTTLALQFLAEGLRRGEKGLYV---SFEESP-EQLLRRAESLGLDL-EEYIESGLLRI----ID---- 87
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 18394225 182 ekcdliiVDTSGRHKQAASLFEEMRQVAEATEPDLVIFvmDS 223
Cdd:COG0467 88 -------LSPEELGLDLEELLARLREAVEEFGAKRVVI--DS 120
|
|
| flhF |
PRK14721 |
flagellar biosynthesis regulator FlhF; Provisional |
100-281 |
2.62e-04 |
|
flagellar biosynthesis regulator FlhF; Provisional
Pssm-ID: 173184 [Multi-domain] Cd Length: 420 Bit Score: 43.40 E-value: 2.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 100 KPSVVMFVGLQGAGKTTTCTKYAY--YHQKKGYKAALVCADTFRAGAFDQLKqnatkakipFYG--------SYTESDPV 169
Cdd:PRK14721 190 QGGVYALIGPTGVGKTTTTAKLAAraVIRHGADKVALLTTDSYRIGGHEQLR---------IYGkllgvsvrSIKDIADL 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394225 170 KIAVegvDRFKKEKcdLIIVDTSGRHKQAASLFEEMRQVAEA-TEPDLVIFVMDSSIGQAAFEQAEAFKETvSVGAVIIT 248
Cdd:PRK14721 261 QLML---HELRGKH--MVLIDTVGMSQRDQMLAEQIAMLSQCgTQVKHLLLLNATSSGDTLDEVISAYQGH-GIHGCIIT 334
|
170 180 190
....*....|....*....|....*....|...
gi 18394225 249 KMDGHAKGGGALSAVAATKSPVIFIGTGEHMDE 281
Cdd:PRK14721 335 KVDEAASLGIALDAVIRRKLVLHYVTNGQKVPE 367
|
|
| |
