NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|17568105|ref|NP_508182|]
View 

Phosphatidylcholine:ceramide cholinephosphotransferase 2 [Caenorhabditis elegans]

Protein Classification

sphingomyelin synthase family protein( domain architecture ID 10627211)

sphingomyelin synthase family protein belonging to the type 2 phosphatidic acid phosphatase (PAP2) superfamily, similar to phosphatidylinositol:ceramide inositolphosphotransferase that is capable of converting phosphatidylinositol (PI) and ceramide to inositol-phosphorylceramide (IPC) and diacylglycerol (DAG) and vice versa

CATH:  1.20.144.10
EC:  2.7.8.-
Gene Ontology:  GO:0016780|GO:0016310
PubMed:  9122162|14685263
SCOP:  3001110

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PAP2_C pfam14360
PAP2 superfamily C-terminal; This family is closely related to the C-terminal a region of PAP2.
 201-273 6.57e-22

PAP2 superfamily C-terminal; This family is closely related to the C-terminal a region of PAP2.


:

Pssm-ID: 464150  Cd Length: 74  Bit Score: 87.65  E-value: 6.57e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17568105   201 LCGDLMFSGHTVVLTIMYFVQLQYTPRGLVILRYIAAPITFLGIAALVVSGGHYTMDVLIAYWLTSHVFWSYH 273
Cdd:pfam14360   1 GCGDLIFSGHTVFTTLFVLFIWEYSPRRLWILKVILWLLAAIGYFLIIASRKHYTVDVLLGYYITTLVFLLYH 73
 
Name Accession Description Interval E-value
PAP2_C pfam14360
PAP2 superfamily C-terminal; This family is closely related to the C-terminal a region of PAP2.
 201-273 6.57e-22

PAP2 superfamily C-terminal; This family is closely related to the C-terminal a region of PAP2.


Pssm-ID: 464150  Cd Length: 74  Bit Score: 87.65  E-value: 6.57e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17568105   201 LCGDLMFSGHTVVLTIMYFVQLQYTPRGLVILRYIAAPITFLGIAALVVSGGHYTMDVLIAYWLTSHVFWSYH 273
Cdd:pfam14360   1 GCGDLIFSGHTVFTTLFVLFIWEYSPRRLWILKVILWLLAAIGYFLIIASRKHYTVDVLLGYYITTLVFLLYH 73
 
Name Accession Description Interval E-value
PAP2_C pfam14360
PAP2 superfamily C-terminal; This family is closely related to the C-terminal a region of PAP2.
 201-273 6.57e-22

PAP2 superfamily C-terminal; This family is closely related to the C-terminal a region of PAP2.


Pssm-ID: 464150  Cd Length: 74  Bit Score: 87.65  E-value: 6.57e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17568105   201 LCGDLMFSGHTVVLTIMYFVQLQYTPRGLVILRYIAAPITFLGIAALVVSGGHYTMDVLIAYWLTSHVFWSYH 273
Cdd:pfam14360   1 GCGDLIFSGHTVFTTLFVLFIWEYSPRRLWILKVILWLLAAIGYFLIIASRKHYTVDVLLGYYITTLVFLLYH 73
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH