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Conserved domains on  [gi|17559154|ref|NP_505981|]
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Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans]

Protein Classification

cuticular collagen family protein( domain architecture ID 18387949)

cuticular collagen family protein is a structural macromolecule of the extracellular matrix containing triple helix domains that form tight interactions and stabilize supramolecular aggregates

Gene Ontology:  GO:0042302|GO:0005581
PubMed:  1916105|21421911

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 5-57 3.44e-15

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


:

Pssm-ID: 198156  Cd Length: 53  Bit Score: 68.65  E-value: 3.44e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 17559154      5 KATAGALCLSSATLILSLYAIFSIYSDVQSIWSQLDQEMDQFKVTTDDLWTQM 57
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 110-281 1.97e-11

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 64.54  E-value: 1.97e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17559154  110 PAGPSGPQGSAGPDGIPGIDGQDGFPGENAEDSQNAPFNGciTCAPGKPGSPGERGKPGLRGMRGPRGTGGSPGTDGYPG 189
Cdd:NF038329 127 PAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGP--QGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAG 204

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17559154  190 RPGEMGPPGPPGDDGKPGSNGEKGQDVEQPTPRKGPRGPPGDSGPPGPEGDAGNDGPVGAAGAPGPDGINGFQGPGGPPG 269
Cdd:NF038329 205 EQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVG 284

                        170
                 ....*....|..
gi 17559154  270 EEGKPGEDGKVG 281
Cdd:NF038329 285 PAGKDGQNGKDG 296
 
Name Accession Description Interval E-value
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 5-57 3.44e-15

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 198156  Cd Length: 53  Bit Score: 68.65  E-value: 3.44e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 17559154      5 KATAGALCLSSATLILSLYAIFSIYSDVQSIWSQLDQEMDQFKVTTDDLWTQM 57
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
Col_cuticle_N pfam01484
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 9-57 2.22e-14

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens, see pfam01391. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 460226  Cd Length: 50  Bit Score: 66.33  E-value: 2.22e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 17559154     9 GALCLSSATLILSLYAIFSIYSDVQSIWSQLDQEMDQFKVTTDDLWTQM 57
Cdd:pfam01484   2 VAVAFSTVAILSSLITLPSIYNDIQELQSEVLDEMDEFKARSDDAWNEM 50
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 110-281 1.97e-11

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 64.54  E-value: 1.97e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17559154  110 PAGPSGPQGSAGPDGIPGIDGQDGFPGENAEDSQNAPFNGciTCAPGKPGSPGERGKPGLRGMRGPRGTGGSPGTDGYPG 189
Cdd:NF038329 127 PAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGP--QGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAG 204

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17559154  190 RPGEMGPPGPPGDDGKPGSNGEKGQDVEQPTPRKGPRGPPGDSGPPGPEGDAGNDGPVGAAGAPGPDGINGFQGPGGPPG 269
Cdd:NF038329 205 EQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVG 284

                        170
                 ....*....|..
gi 17559154  270 EEGKPGEDGKVG 281
Cdd:NF038329 285 PAGKDGQNGKDG 296
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 110-283 8.87e-08

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 53.37  E-value: 8.87e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17559154  110 PAGPSGPQGSAGPDGIPGIDGQDGFPGENAEDSQNAPFNgcitcAPGKPGSPGERGKPGLRGMRGPRGTGGSPGTDGyPG 189
Cdd:NF038329 160 EKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRG-----ETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAG-DG 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17559154  190 RPGEMGPPGPPGDDGKPGSNGEKGQDVEqptprKGPRGPPGDSGPPGPEGDAGNDGPVGAAGAPGPDGINGFQGPGGPPG 269
Cdd:NF038329 234 QQGPDGDPGPTGEDGPQGPDGPAGKDGP-----RGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNG 308

                        170
                 ....*....|....
gi 17559154  270 EEGKPGEDGKVGDD 283
Cdd:NF038329 309 KDGLPGKDGKDGQP 322
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 110-288 7.36e-07

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 50.67  E-value: 7.36e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17559154  110 PAGPSGPQGSAGPDGIPGIDGQDGFPGENAEDSQNAPFNgcITCAPGKPGSPGERGKPGLRGmRGPRGTGGSPGTDGYPG 189
Cdd:NF038329 172 PQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAG--PAGPDGEAGPAGEDGPAGPAG-DGQQGPDGDPGPTGEDG 248

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17559154  190 RPGEMGPPGPPGDDGKPGSNGEKGQDVEQPtpRKGPRGPPGDSGPPGPEGDAGNDGPVGAAGAPGPDGINGFQGPGGPPG 269
Cdd:NF038329 249 PQGPDGPAGKDGPRGDRGEAGPDGPDGKDG--ERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDG 326

                        170
                 ....*....|....*....
gi 17559154  270 EEGKPGEDGKVGDDAAYCP 288
Cdd:NF038329 327 LPGKDGKDGQPGKPAPKTP 345
 
Name Accession Description Interval E-value
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 5-57 3.44e-15

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 198156  Cd Length: 53  Bit Score: 68.65  E-value: 3.44e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 17559154      5 KATAGALCLSSATLILSLYAIFSIYSDVQSIWSQLDQEMDQFKVTTDDLWTQM 57
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
Col_cuticle_N pfam01484
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 9-57 2.22e-14

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens, see pfam01391. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 460226  Cd Length: 50  Bit Score: 66.33  E-value: 2.22e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 17559154     9 GALCLSSATLILSLYAIFSIYSDVQSIWSQLDQEMDQFKVTTDDLWTQM 57
Cdd:pfam01484   2 VAVAFSTVAILSSLITLPSIYNDIQELQSEVLDEMDEFKARSDDAWNEM 50
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 110-281 1.97e-11

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 64.54  E-value: 1.97e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17559154  110 PAGPSGPQGSAGPDGIPGIDGQDGFPGENAEDSQNAPFNGciTCAPGKPGSPGERGKPGLRGMRGPRGTGGSPGTDGYPG 189
Cdd:NF038329 127 PAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGP--QGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAG 204

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17559154  190 RPGEMGPPGPPGDDGKPGSNGEKGQDVEQPTPRKGPRGPPGDSGPPGPEGDAGNDGPVGAAGAPGPDGINGFQGPGGPPG 269
Cdd:NF038329 205 EQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVG 284

                        170
                 ....*....|..
gi 17559154  270 EEGKPGEDGKVG 281
Cdd:NF038329 285 PAGKDGQNGKDG 296
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 110-283 8.87e-08

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 53.37  E-value: 8.87e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17559154  110 PAGPSGPQGSAGPDGIPGIDGQDGFPGENAEDSQNAPFNgcitcAPGKPGSPGERGKPGLRGMRGPRGTGGSPGTDGyPG 189
Cdd:NF038329 160 EKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRG-----ETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAG-DG 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17559154  190 RPGEMGPPGPPGDDGKPGSNGEKGQDVEqptprKGPRGPPGDSGPPGPEGDAGNDGPVGAAGAPGPDGINGFQGPGGPPG 269
Cdd:NF038329 234 QQGPDGDPGPTGEDGPQGPDGPAGKDGP-----RGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNG 308

                        170
                 ....*....|....
gi 17559154  270 EEGKPGEDGKVGDD 283
Cdd:NF038329 309 KDGLPGKDGKDGQP 322
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 110-288 7.36e-07

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 50.67  E-value: 7.36e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17559154  110 PAGPSGPQGSAGPDGIPGIDGQDGFPGENAEDSQNAPFNgcITCAPGKPGSPGERGKPGLRGmRGPRGTGGSPGTDGYPG 189
Cdd:NF038329 172 PQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAG--PAGPDGEAGPAGEDGPAGPAG-DGQQGPDGDPGPTGEDG 248

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17559154  190 RPGEMGPPGPPGDDGKPGSNGEKGQDVEQPtpRKGPRGPPGDSGPPGPEGDAGNDGPVGAAGAPGPDGINGFQGPGGPPG 269
Cdd:NF038329 249 PQGPDGPAGKDGPRGDRGEAGPDGPDGKDG--ERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDG 326

                        170
                 ....*....|....*....
gi 17559154  270 EEGKPGEDGKVGDDAAYCP 288
Cdd:NF038329 327 LPGKDGKDGQPGKPAPKTP 345
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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