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Conserved domains on  [gi|17562110|ref|NP_504261|]
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Transcription initiation factor TFIID subunit 10 [Caenorhabditis elegans]

Protein Classification

transcription initiation factor TFIID subunit 10( domain architecture ID 10168402)

transcription initiation factor TFIID subunit 10 is part of the multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HFD_TAF10 cd07982
histone-fold domain found in transcription initiation factor TFIID subunit 10 (TAF10) and ...
 74-166 8.24e-38

histone-fold domain found in transcription initiation factor TFIID subunit 10 (TAF10) and similar proteins; TAF10, also called TATA Binding Protein (TBP) associated factor 10, STAF28, transcription initiation factor TFIID 30 kDa subunit, TAF(II)30, TAFII-30, or TAFII30, is a TBP-associated factor (TAF). TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex, and TBP-free TAFII complex (TFTC). TIIFD is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. TFIID and PCAF are composed of TATA binding protein (TBP) and several TAFs. TBP is not part of TFTC. TAF10 regulates genes that are important for cell cycle progression and cell morphology. A lack of TAF10 leads to cell cycle arrest and cell death by apoptosis in mice.


:

Pssm-ID: 467026  Cd Length: 98  Bit Score: 125.37  E-value: 8.24e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562110  74 DDTHEFINQLADYPPTIPDSVTLHFLKSAGVDGSDPRVTRMISLAAQKHVSDIILDAMTSARMKGLGQTK--KGTKDTKY 151
Cdd:cd07982   1 KELEEFLEQLEDYTPTIPDEVTQYYLERAGFQTSDPRVVRLISLAAQKFISDIANDALQYCKMRQSAQKKkgKKGKDKKL 80

                        90
                ....*....|....*
gi 17562110 152 TLTEELLDEILKEYG 166
Cdd:cd07982  81 VLTMEDLAAALKEYG 95
 
Name Accession Description Interval E-value
HFD_TAF10 cd07982
histone-fold domain found in transcription initiation factor TFIID subunit 10 (TAF10) and ...
 74-166 8.24e-38

histone-fold domain found in transcription initiation factor TFIID subunit 10 (TAF10) and similar proteins; TAF10, also called TATA Binding Protein (TBP) associated factor 10, STAF28, transcription initiation factor TFIID 30 kDa subunit, TAF(II)30, TAFII-30, or TAFII30, is a TBP-associated factor (TAF). TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex, and TBP-free TAFII complex (TFTC). TIIFD is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. TFIID and PCAF are composed of TATA binding protein (TBP) and several TAFs. TBP is not part of TFTC. TAF10 regulates genes that are important for cell cycle progression and cell morphology. A lack of TAF10 leads to cell cycle arrest and cell death by apoptosis in mice.


Pssm-ID: 467026  Cd Length: 98  Bit Score: 125.37  E-value: 8.24e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562110  74 DDTHEFINQLADYPPTIPDSVTLHFLKSAGVDGSDPRVTRMISLAAQKHVSDIILDAMTSARMKGLGQTK--KGTKDTKY 151
Cdd:cd07982   1 KELEEFLEQLEDYTPTIPDEVTQYYLERAGFQTSDPRVVRLISLAAQKFISDIANDALQYCKMRQSAQKKkgKKGKDKKL 80

                        90
                ....*....|....*
gi 17562110 152 TLTEELLDEILKEYG 166
Cdd:cd07982  81 VLTMEDLAAALKEYG 95
TFIID_30kDa pfam03540
Transcription initiation factor TFIID 23-30kDa subunit;
89-137 1.57e-22

Transcription initiation factor TFIID 23-30kDa subunit;


Pssm-ID: 460964  Cd Length: 49  Bit Score: 84.87  E-value: 1.57e-22
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 17562110    89 TIPDSVTLHFLKSAGVDGSDPRVTRMISLAAQKHVSDIILDAMTSARMK 137
Cdd:pfam03540   1 TIPDEVTDYYLEKAGFETSDPRVKRLISLAAQKFISDIANDAYQYAKIR 49
COG5162 COG5162
Transcription initiation factor TFIID, subunit TAF10 (also component of histone ...
 78-175 1.52e-15

Transcription initiation factor TFIID, subunit TAF10 (also component of histone acetyltransferase SAGA) [Transcription];


Pssm-ID: 227491  Cd Length: 197  Bit Score: 70.85  E-value: 1.52e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562110  78 EFINQLADYPPTIPDSVTLHFLKSAGVDGSDPRVTRMISLAAQKHVSDIILDAMTSARMK-------------------- 137
Cdd:COG5162  77 ELLQNMDSYTPLIPDSVTDYYLEKAGFVTSDQRVKKLLSLLAQKFVSDIAVDAYQYSRIRqgssnakataqkakrfakgg 156

                        90       100       110       120
                ....*....|....*....|....*....|....*....|
gi 17562110 138 --GLGQTKKGTKDTKYTLTEELLDEILKEYGHQNTRPPYH 175
Cdd:COG5162 157 asGIGSSGRRGDRKKPVLTVVDLSKALEEYGINISRPDFY 196
 
Name Accession Description Interval E-value
HFD_TAF10 cd07982
histone-fold domain found in transcription initiation factor TFIID subunit 10 (TAF10) and ...
 74-166 8.24e-38

histone-fold domain found in transcription initiation factor TFIID subunit 10 (TAF10) and similar proteins; TAF10, also called TATA Binding Protein (TBP) associated factor 10, STAF28, transcription initiation factor TFIID 30 kDa subunit, TAF(II)30, TAFII-30, or TAFII30, is a TBP-associated factor (TAF). TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex, and TBP-free TAFII complex (TFTC). TIIFD is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. TFIID and PCAF are composed of TATA binding protein (TBP) and several TAFs. TBP is not part of TFTC. TAF10 regulates genes that are important for cell cycle progression and cell morphology. A lack of TAF10 leads to cell cycle arrest and cell death by apoptosis in mice.


Pssm-ID: 467026  Cd Length: 98  Bit Score: 125.37  E-value: 8.24e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562110  74 DDTHEFINQLADYPPTIPDSVTLHFLKSAGVDGSDPRVTRMISLAAQKHVSDIILDAMTSARMKGLGQTK--KGTKDTKY 151
Cdd:cd07982   1 KELEEFLEQLEDYTPTIPDEVTQYYLERAGFQTSDPRVVRLISLAAQKFISDIANDALQYCKMRQSAQKKkgKKGKDKKL 80

                        90
                ....*....|....*
gi 17562110 152 TLTEELLDEILKEYG 166
Cdd:cd07982  81 VLTMEDLAAALKEYG 95
TFIID_30kDa pfam03540
Transcription initiation factor TFIID 23-30kDa subunit;
89-137 1.57e-22

Transcription initiation factor TFIID 23-30kDa subunit;


Pssm-ID: 460964  Cd Length: 49  Bit Score: 84.87  E-value: 1.57e-22
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 17562110    89 TIPDSVTLHFLKSAGVDGSDPRVTRMISLAAQKHVSDIILDAMTSARMK 137
Cdd:pfam03540   1 TIPDEVTDYYLEKAGFETSDPRVKRLISLAAQKFISDIANDAYQYAKIR 49
COG5162 COG5162
Transcription initiation factor TFIID, subunit TAF10 (also component of histone ...
 78-175 1.52e-15

Transcription initiation factor TFIID, subunit TAF10 (also component of histone acetyltransferase SAGA) [Transcription];


Pssm-ID: 227491  Cd Length: 197  Bit Score: 70.85  E-value: 1.52e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562110  78 EFINQLADYPPTIPDSVTLHFLKSAGVDGSDPRVTRMISLAAQKHVSDIILDAMTSARMK-------------------- 137
Cdd:COG5162  77 ELLQNMDSYTPLIPDSVTDYYLEKAGFVTSDQRVKKLLSLLAQKFVSDIAVDAYQYSRIRqgssnakataqkakrfakgg 156

                        90       100       110       120
                ....*....|....*....|....*....|....*....|
gi 17562110 138 --GLGQTKKGTKDTKYTLTEELLDEILKEYGHQNTRPPYH 175
Cdd:COG5162 157 asGIGSSGRRGDRKKPVLTVVDLSKALEEYGINISRPDFY 196
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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