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Conserved domains on  [gi|17560436|ref|NP_504200|]
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dolichyl-phosphate-mannose--protein mannosyltransferase [Caenorhabditis elegans]

Protein Classification

DUF1736 and TPR domain-containing protein( domain architecture ID 12091460)

DUF1736 and TPR domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 244-316 6.16e-32

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


:

Pssm-ID: 462468  Cd Length: 75  Bit Score: 118.40  E-value: 6.16e-32
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17560436   244 NFQSPKFSKNDNPIAHEPNSLTRALTFMYLPVFHLNLIVFPKTLSYDWSMDAIPKVESLIDSRIILTFIVIGV 316
Cdd:pfam08409   1 GGQLPVFSASDNPAAFSPSLLTRTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYGA 73
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
587-748 8.78e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 98.16  E-value: 8.78e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 587 PSVLNSMGTCYNELGDEQSAEKFFGKA--IGENHVNSYLTMAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIALAEF 664
Cdd:COG0457   8 AEAYNNLGLAYRRLGRYEEAIEDYEKAleLDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQ 87

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 665 HMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSYAAHANYGAILHLNQKYDLALKEY 744
Cdd:COG0457  88 ALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELL 167


                ....
gi 17560436 745 EIAL 748
Cdd:COG0457 168 EKLE 171
PEP_TPR_lipo super family cl37187
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 413-757 2.76e-11

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


The actual alignment was detected with superfamily member TIGR02917:

Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 67.42  E-value: 2.76e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   413 MQRVDDWKTEESLFKSALEVNPTKANMnLGYVYTTQKKYELAKYHYRQALKRQGNLADAWYNLGIltSKTS-NNSNGSIH 491
Cdd:TIGR02917 342 LGRVDEAIATLSPALGLDPDDPAALSL-LGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGI--SKLSqGDPSEAIA 418

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   492 CYQMALQSRStyaaahlnlallLHDAGHHMAAFSHLDkclnnTGEFLKFYHVNRKTQATCAFN------KGRLLQKSGNF 565
Cdd:TIGR02917 419 DLETAAQLDP------------ELGRADLLLILSYLR-----SGQFDKALAAAKKLEKKQPDNaslhnlLGAIYLGKGDL 481

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   566 HVAIENFELALKLGGPHFehtPSVLNSMGTCYNElGDEQSAEKFFGKAIGE--NHVNSYLTMAHLKIRQNRSFEVENLLR 643
Cdd:TIGR02917 482 AKAREAFEKALSIEPDFF---PAAANLARIDIQE-GNPDDAIQRFEKVLTIdpKNLRAILALAGLYLRTGNEEEAVAWLE 557

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   644 KAMTLAPESVTVLqnIALAEFHMQNYN--RSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSY 721
Cdd:TIGR02917 558 KAAELNPQEIEPA--LALAQYYLGKGQlkKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSA 635

                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 17560436   722 AAHANYGAILHLNQKYDLALKEYEIALILDPTSDVA 757
Cdd:TIGR02917 636 LALLLLADAYAVMKNYAKAITSLKRALELKPDNTEA 671
 
Name Accession Description Interval E-value
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 244-316 6.16e-32

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


Pssm-ID: 462468  Cd Length: 75  Bit Score: 118.40  E-value: 6.16e-32
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17560436   244 NFQSPKFSKNDNPIAHEPNSLTRALTFMYLPVFHLNLIVFPKTLSYDWSMDAIPKVESLIDSRIILTFIVIGV 316
Cdd:pfam08409   1 GGQLPVFSASDNPAAFSPSLLTRTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYGA 73
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
587-748 8.78e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 98.16  E-value: 8.78e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 587 PSVLNSMGTCYNELGDEQSAEKFFGKA--IGENHVNSYLTMAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIALAEF 664
Cdd:COG0457   8 AEAYNNLGLAYRRLGRYEEAIEDYEKAleLDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQ 87

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 665 HMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSYAAHANYGAILHLNQKYDLALKEY 744
Cdd:COG0457  88 ALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELL 167


                ....
gi 17560436 745 EIAL 748
Cdd:COG0457 168 EKLE 171
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 413-757 2.76e-11

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 67.42  E-value: 2.76e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   413 MQRVDDWKTEESLFKSALEVNPTKANMnLGYVYTTQKKYELAKYHYRQALKRQGNLADAWYNLGIltSKTS-NNSNGSIH 491
Cdd:TIGR02917 342 LGRVDEAIATLSPALGLDPDDPAALSL-LGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGI--SKLSqGDPSEAIA 418

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   492 CYQMALQSRStyaaahlnlallLHDAGHHMAAFSHLDkclnnTGEFLKFYHVNRKTQATCAFN------KGRLLQKSGNF 565
Cdd:TIGR02917 419 DLETAAQLDP------------ELGRADLLLILSYLR-----SGQFDKALAAAKKLEKKQPDNaslhnlLGAIYLGKGDL 481

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   566 HVAIENFELALKLGGPHFehtPSVLNSMGTCYNElGDEQSAEKFFGKAIGE--NHVNSYLTMAHLKIRQNRSFEVENLLR 643
Cdd:TIGR02917 482 AKAREAFEKALSIEPDFF---PAAANLARIDIQE-GNPDDAIQRFEKVLTIdpKNLRAILALAGLYLRTGNEEEAVAWLE 557

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   644 KAMTLAPESVTVLqnIALAEFHMQNYN--RSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSY 721
Cdd:TIGR02917 558 KAAELNPQEIEPA--LALAQYYLGKGQlkKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSA 635

                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 17560436   722 AAHANYGAILHLNQKYDLALKEYEIALILDPTSDVA 757
Cdd:TIGR02917 636 LALLLLADAYAVMKNYAKAITSLKRALELKPDNTEA 671
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 565-755 9.35e-10

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 61.92  E-value: 9.35e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   565 FHVAIENFELALKLG--GPHFEHTpsvLNSMGTCYNELGDEQSAEKFFGKAIG-ENHVN-SYLTMAHLKIRQNRSFEVEN 640
Cdd:TIGR00990 310 YEEAARAFEKALDLGklGEKEAIA---LNLRGTFKCLKGKHLEALADLSKSIElDPRVTqSYIKRASMNLELGDPDKAEE 386

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   641 LLRKAMTLAPESVTVLQNIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNS 720
Cdd:TIGR00990 387 DFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPEA 466

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 17560436   721 YAAHANYGAILHLNQKYDLALKEYEIALILDPTSD 755
Cdd:TIGR00990 467 PDVYNYYGELLLDQNKFDEAIEKFDTAIELEKETK 501
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 410-578 9.87e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.85  E-value: 9.87e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 410 IRTMQRVDDWKTEESLFKSALEVNPT--KANMNLGYVYTTQKKYELAKYHYRQALKRQGNLADAWYNLGiltsktsnnsn 487
Cdd:COG3914  85 ALLLQALGRYEEALALYRRALALNPDnaEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLG----------- 153

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 488 gsihcyqMALQSRstyaaahlnlalllhdaGHHMAAFSHLDKCLNNTGEFLKFYhvnrktqatcaFNKGRLLQKSGNFHV 567
Cdd:COG3914 154 -------EALRRL-----------------GRLEEAIAALRRALELDPDNAEAL-----------NNLGNALQDLGRLEE 198

                       170
                ....*....|.
gi 17560436 568 AIENFELALKL 578
Cdd:COG3914 199 AIAAYRRALEL 209
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 571-715 1.25e-06

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 51.09  E-value: 1.25e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 571 NFELALKLGGPHFEHTPS---VLNSMGTCYNELGDEQSAEKFFGKAI----GENHVnSYLTMAHLKIRQN--RSFE--VE 639
Cdd:cd24142  15 NFELALKFLQRALELEPNnveALELLGEILLELGDVEEAREVLLRAIeldpDGGYE-KYLYLGQLSGGEEalQYYEkgIE 93

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 640 NLLRKAMTL------APESVTVLQN------IALAEFHM----------QNYNRSLlfyRKALHLDPTHLDSLQGIANLL 697
Cdd:cd24142  94 ILEEELQALqaasaeAEEEAEELKRklssalCALAEIYMtdlcdepdaeQRCEELI---TKALELDPTNPEALQTLASLR 170

                       170
                ....*....|....*...
gi 17560436 698 QQTQNHVESETFYRKVME 715
Cdd:cd24142 171 ISQQRPDEAKEALRRSLE 188
TPR_12 pfam13424
Tetratricopeptide repeat;
554-614 1.54e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 43.53  E-value: 1.54e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17560436   554 NKGRLLQKSGNFHVAIENFELAL----KLGGPHFEHTPSVLNSMGTCYNELGDEQSAEKFFGKAI 614
Cdd:pfam13424   8 NLAAVLRRLGRYDEALELLEKALeiarRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERAL 72
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 556-663 5.17e-04

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 43.07  E-value: 5.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   556 GRLLQKSGNFHVAIENFELALKLGG-PHFEHTPSV---LNSMGTCYNELGDEQSAEKFFGKAI-----GENH--VNSYLT 624
Cdd:pfam17874  87 GEILRAQGRLHQALETYQQALQLARdHGLQHLPLHgflLVGLADLLYEWNDLEEAEQHAQQGIqlgrqWEPDaaVDAYVL 166

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 17560436   625 MAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIALAE 663
Cdd:pfam17874 167 LARIALAQGELEEALTLLRRAELLARQSFFHVDWLANAE 205
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 655-686 5.22e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.11  E-value: 5.22e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 17560436    655 VLQNIALAEFHMQNYNRSLLFYRKALHLDPTH 686
Cdd:smart00028   3 ALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
 
Name Accession Description Interval E-value
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 244-316 6.16e-32

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


Pssm-ID: 462468  Cd Length: 75  Bit Score: 118.40  E-value: 6.16e-32
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17560436   244 NFQSPKFSKNDNPIAHEPNSLTRALTFMYLPVFHLNLIVFPKTLSYDWSMDAIPKVESLIDSRIILTFIVIGV 316
Cdd:pfam08409   1 GGQLPVFSASDNPAAFSPSLLTRTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYGA 73
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
587-748 8.78e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 98.16  E-value: 8.78e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 587 PSVLNSMGTCYNELGDEQSAEKFFGKA--IGENHVNSYLTMAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIALAEF 664
Cdd:COG0457   8 AEAYNNLGLAYRRLGRYEEAIEDYEKAleLDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQ 87

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 665 HMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSYAAHANYGAILHLNQKYDLALKEY 744
Cdd:COG0457  88 ALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELL 167


                ....
gi 17560436 745 EIAL 748
Cdd:COG0457 168 EKLE 171
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
548-774 1.48e-22

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 97.38  E-value: 1.48e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 548 QATCAFNKGRLLQKSGNFHVAIENFELALKLggphFEHTPSVLNSMGTCYNELGDEQSAEKFFGKAI--GENHVNSYLTM 625
Cdd:COG0457   7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALEL----DPDDAEALYNLGLAYLRLGRYEEALADYEQALelDPDDAEALNNL 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 626 AHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVE 705
Cdd:COG0457  83 GLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEE 162

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17560436 706 SETFYRKVMEAQPNSYAAHANYGAILHLNQKYDLALKEYEIALILDPTSDVARENRKKVIRILRRKRNL 774
Cdd:COG0457 163 ALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLL 231
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
613-771 1.76e-22

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 97.38  E-value: 1.76e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 613 AIGENHVNSYLTMAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQG 692
Cdd:COG0457   2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNN 81

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17560436 693 IANLLQQTQNHVESETFYRKVMEAQPNSYAAHANYGAILHLNQKYDLALKEYEIALILDPTSDVARENRKKVIRILRRK 771
Cdd:COG0457  82 LGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 553-770 7.11e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 87.48  E-value: 7.11e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 553 FNKGRLLQKSGNFHVAIENFELALKLGgphfEHTPSVLNSMGTCYNELGDEQSAEKFFGKAIGEN--HVNSYLTMAHLKI 630
Cdd:COG2956  46 LALGNLYRRRGEYDRAIRIHQKLLERD----PDRAEALLELAQDYLKAGLLDRAEELLEKLLELDpdDAEALRLLAEIYE 121

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 631 RQNRSFEVENLLRKAMTLAPESVTVLQNIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFY 710
Cdd:COG2956 122 QEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAAL 201

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17560436 711 RKVMEAQPNSYAAHANYGAILHLNQKYDLALKEYEIALILDPTSDV---------ARENRKKVIRILRR 770
Cdd:COG2956 202 ERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLllaladlleRKEGLEAALALLER 270
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 622-752 1.49e-18

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 82.55  E-value: 1.49e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 622 YLTMAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQ 701
Cdd:COG4783   7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAG 86

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 17560436 702 NHVESETFYRKVMEAQPNSYAAHANYGAILHLNQKYDLALKEYEIALILDP 752
Cdd:COG4783  87 DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 626-758 7.74e-18

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 88.13  E-value: 7.74e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 626 AHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVE 705
Cdd:COG3914  85 ALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEE 164

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|...
gi 17560436 706 SETFYRKVMEAQPNSYAAHANYGAILHLNQKYDLALKEYEIALILDPTSDVAR 758
Cdd:COG3914 165 AIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAH 217
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 642-758 1.04e-16

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 76.97  E-value: 1.04e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 642 LRKAMTLAPESVTVLQNIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSY 721
Cdd:COG4235   6 LRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                        90       100       110
                ....*....|....*....|....*....|....*..
gi 17560436 722 AAHANYGAILHLNQKYDLALKEYEIALILDPTSDVAR 758
Cdd:COG4235  86 EALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPAR 122
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 599-727 1.43e-16

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 83.89  E-value: 1.43e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 599 ELGDEQSAEKFFGKAIGEN--HVNSYLTMAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIALAEFHMQNYNRSLLFY 676
Cdd:COG3914  90 ALGRYEEALALYRRALALNpdNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAAL 169

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 17560436 677 RKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSYAAHANY 727
Cdd:COG3914 170 RRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 588-720 1.67e-16

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 76.77  E-value: 1.67e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 588 SVLNSMGTCYNELGDEQSAEKFFGKAIGEN--HVNSYLTMAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIALAEFH 665
Cdd:COG4783   5 EALYALAQALLLAGDYDEAEALLEKALELDpdNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 17560436 666 MQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNS 720
Cdd:COG4783  85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 594-770 3.59e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 79.39  E-value: 3.59e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 594 GTCYNELGDEQSAEKFFGKAIGEN--HVNSYLTMAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIALAEFHMQNYNR 671
Cdd:COG2956  15 GLNYLLNGQPDKAIDLLEEALELDpeTVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDR 94

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 672 SLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSYAAHANYGAILHLNQKYDLALKEYEIALILD 751
Cdd:COG2956  95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLD 174

                       170       180
                ....*....|....*....|....*....
gi 17560436 752 PTSDVAR----------ENRKKVIRILRR 770
Cdd:COG2956 175 PDCARALlllaelyleqGDYEEAIAALER 203
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 441-748 8.29e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 75.54  E-value: 8.29e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 441 LGYVYTTQKKYELAKYHYRQALKRQGNLADAWYNLGiltsktsnnsngsiHCYQMalqsrstyaaahlnlalllhdAGHH 520
Cdd:COG2956  14 KGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALG--------------NLYRR---------------------RGEY 58

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 521 MAAFSHLDKCLNNTGEFLKFYhvnrktqatcaFNKGRLLQKSGNFHVAIENFELALKLGgphfEHTPSVLNSMGTCYNEL 600
Cdd:COG2956  59 DRAIRIHQKLLERDPDRAEAL-----------LELAQDYLKAGLLDRAEELLEKLLELD----PDDAEALRLLAEIYEQE 123

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 601 GDEQSAEKFFGKAIGENHVNS--YLTMAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIALAEFHMQNYNRSLLFYRK 678
Cdd:COG2956 124 GDWEKAIEVLERLLKLGPENAhaYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALER 203

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 679 ALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSyAAHANYGAILHLNQKYDLALKEYEIAL 748
Cdd:COG2956 204 ALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKEGLEAALALLERQL 272
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 623-753 2.88e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 76.57  E-value: 2.88e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 623 LTMAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQN 702
Cdd:COG3914  48 LAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGR 127

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 17560436 703 HVESETFYRKVMEAQPNSYAAHANYGAILHLNQKYDLALKEYEIALILDPT 753
Cdd:COG3914 128 LEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPD 178
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 655-771 5.59e-14

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 69.45  E-value: 5.59e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 655 VLQNIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSYAAHANYGAILHLN 734
Cdd:COG4783   6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                        90       100       110
                ....*....|....*....|....*....|....*..
gi 17560436 735 QKYDLALKEYEIALILDPTSDVARENRKKVIRILRRK 771
Cdd:COG4783  86 GDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRP 122
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 556-767 1.39e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 74.26  E-value: 1.39e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 556 GRLLQKSGNFHVAIENFELALKLGgPHFehtPSVLNSMGTCYNELGDEQSAEKFFGKAIGEN--HVNSYLTMAHLKIRQN 633
Cdd:COG3914  85 ALLLQALGRYEEALALYRRALALN-PDN---AEALFNLGNLLLALGRLEEALAALRRALALNpdFAEAYLNLGEALRRLG 160

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 634 RSFEVENLLRKAMTLAPESVTVLQNIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKV 713
Cdd:COG3914 161 RLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELL 240

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17560436 714 MEAQPNS---------YAAHANYGAILHLNQKYDlalKEYEIALILDPTSDVARENRKKVIRI 767
Cdd:COG3914 241 AALARGPselspfallYLPDDDPAELLALARAWA---QLVAAAAAPELPPPPNPRDPDRKLRI 300
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
429-751 1.86e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 70.81  E-value: 1.86e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 429 ALEVNPTKANMNLGYVYTTQKKYELAKYHYRQALKRQGNLADAWYNLGILtsktsnnsngsihcyqmalqsrstyaaahl 508
Cdd:COG0457   2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLA------------------------------ 51

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 509 nlalllhdaghhmaafshldkclnntgeflkfyhvnrktqatcafnkgrlLQKSGNFHVAIENFELALKLGgPHFehtPS 588
Cdd:COG0457  52 --------------------------------------------------YLRLGRYEEALADYEQALELD-PDD---AE 77

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 589 VLNSMGTCYNELGDEQSAEKFFGKA--IGENHVNSYLTMAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIALAEFHM 666
Cdd:COG0457  78 ALNNLGLALQALGRYEEALEDYDKAleLDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKL 157

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 667 QNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSYAAHANYGAILHLNQKYDLALKEYEI 746
Cdd:COG0457 158 GRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAA 237


                ....*
gi 17560436 747 ALILD 751
Cdd:COG0457 238 LALYQ 242
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
423-683 2.68e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 67.34  E-value: 2.68e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 423 ESLFKSALEVNPT--KANMNLGYVYTTQKKYELAKYHYRQALKRQGNLADAWYNLGILTSKTsNNSNGSIHCYQMALQSR 500
Cdd:COG0457  28 IEDYEKALELDPDdaEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQAL-GRYEEALEDYDKALELD 106

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 501 STYaaahlnlalllhdaghhmaafshldkclnntgeflkfyhvnrktqATCAFNKGRLLQKSGNFHVAIENFELALKLGg 580
Cdd:COG0457 107 PDD---------------------------------------------AEALYNLGLALLELGRYDEAIEAYERALELD- 140

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 581 phfEHTPSVLNSMGTCYNELGDEQSAEKFFGKAIGENHVNSYLTMAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIA 660
Cdd:COG0457 141 ---PDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLA 217

                       250       260
                ....*....|....*....|...
gi 17560436 661 LAEFHMQNYNRSLLFYRKALHLD 683
Cdd:COG0457 218 ALAELLLLALALLLALRLAALAL 240
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 423-717 2.79e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.83  E-value: 2.79e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 423 ESLFKSALEVNPTK--ANMNLGYVYTTQKKYELAKYHYRQALKRQGNLADAWYNLgiltsktsnnsngsihcyqmalqsr 500
Cdd:COG2956  62 IRIHQKLLERDPDRaeALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLL------------------------- 116

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 501 styaaahlnlalllhdaghhmaafshldkclnntgeflkfyhvnrktqatcafnkGRLLQKSGNFHVAIENFELALKLGG 580
Cdd:COG2956 117 -------------------------------------------------------AEIYEQEGDWEKAIEVLERLLKLGP 141

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 581 PHfehtPSVLNSMGTCYNELGDEQSAEKFFGKAIGEN--HVNSYLTMAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQN 658
Cdd:COG2956 142 EN----AHAYCELAELYLEQGDYDEAIEALEKALKLDpdCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPR 217

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 17560436 659 IALAEFHMQNYNRSLLFYRKALHLDPThLDSLQGIANLLQQTQNHVESETFYRKVMEAQ 717
Cdd:COG2956 218 LAELYEKLGDPEEALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLERQLRRH 275
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 413-757 2.76e-11

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 67.42  E-value: 2.76e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   413 MQRVDDWKTEESLFKSALEVNPTKANMnLGYVYTTQKKYELAKYHYRQALKRQGNLADAWYNLGIltSKTS-NNSNGSIH 491
Cdd:TIGR02917 342 LGRVDEAIATLSPALGLDPDDPAALSL-LGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGI--SKLSqGDPSEAIA 418

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   492 CYQMALQSRStyaaahlnlallLHDAGHHMAAFSHLDkclnnTGEFLKFYHVNRKTQATCAFN------KGRLLQKSGNF 565
Cdd:TIGR02917 419 DLETAAQLDP------------ELGRADLLLILSYLR-----SGQFDKALAAAKKLEKKQPDNaslhnlLGAIYLGKGDL 481

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   566 HVAIENFELALKLGGPHFehtPSVLNSMGTCYNElGDEQSAEKFFGKAIGE--NHVNSYLTMAHLKIRQNRSFEVENLLR 643
Cdd:TIGR02917 482 AKAREAFEKALSIEPDFF---PAAANLARIDIQE-GNPDDAIQRFEKVLTIdpKNLRAILALAGLYLRTGNEEEAVAWLE 557

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   644 KAMTLAPESVTVLqnIALAEFHMQNYN--RSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSY 721
Cdd:TIGR02917 558 KAAELNPQEIEPA--LALAQYYLGKGQlkKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSA 635

                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 17560436   722 AAHANYGAILHLNQKYDLALKEYEIALILDPTSDVA 757
Cdd:TIGR02917 636 LALLLLADAYAVMKNYAKAITSLKRALELKPDNTEA 671
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 617-720 6.65e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 60.40  E-value: 6.65e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 617 NHVNSYLTMAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQGIANL 696
Cdd:COG4235  15 NDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLA 94

                        90       100
                ....*....|....*....|....
gi 17560436 697 LQQTQNHVESETFYRKVMEAQPNS 720
Cdd:COG4235  95 AFQQGDYAEAIAAWQKLLALLPAD 118
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
662-752 7.43e-11

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 59.41  E-value: 7.43e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 662 AEFHMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFyRKVMEAQPNSYAAHANYGAILHLNQKYDLAL 741
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                        90
                ....*....|.
gi 17560436 742 KEYEIALILDP 752
Cdd:COG3063  80 AYLERALELDP 90
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 641-752 1.48e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 60.36  E-value: 1.48e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 641 LLRKAMTLAPESVTVLQNIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNS 720
Cdd:COG5010  42 LAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDN 121

                        90       100       110
                ....*....|....*....|....*....|..
gi 17560436 721 YAAHANYGAILHLNQKYDLALKEYEIALILDP 752
Cdd:COG5010 122 PNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 423-760 5.89e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 62.79  E-value: 5.89e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   423 ESLFKSALEVNPTK--ANMNLGYVYTTQKKYELAKYHYRQALKRQGNLADAWYNLGILtSKTSNNSNGSIHCYQMALQSR 500
Cdd:TIGR02917 145 QKSYEQALAIDPRSlyAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDL-LLSLGNIELALAAYRKAIALR 223

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   501 STYAAAHLNLALLLHDAGHHMAAFSHLDkclnntgEFLKFyhVNRKTQAtcAFNKGRLLQKSGNFHVAIENFELALKLGg 580
Cdd:TIGR02917 224 PNNIAVLLALATILIEAGEFEEAEKHAD-------ALLKK--APNSPLA--HYLKALVDFQKKNYEDARETLQDALKSA- 291

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   581 phFEHTPSVLNSmGTCYNELGDEQSAEKFFGK--AIGENHVNSYLTMAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQn 658
Cdd:TIGR02917 292 --PEYLPALLLA-GASEYQLGNLEQAYQYLNQilKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALS- 367

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   659 iALAEFHMQN--YNRSLLFYRKALHLDP-----------THL---DSLQGIANLLQQTQ---NHVESETFY--------- 710
Cdd:TIGR02917 368 -LLGEAYLALgdFEKAAEYLAKATELDPenaaartqlgiSKLsqgDPSEAIADLETAAQldpELGRADLLLilsylrsgq 446

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 17560436   711 --------RKVMEAQPNSYAAHANYGAILHLNQKYDLALKEYEIALILDPTSDVAREN 760
Cdd:TIGR02917 447 fdkalaaaKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAAN 504
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 565-755 9.35e-10

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 61.92  E-value: 9.35e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   565 FHVAIENFELALKLG--GPHFEHTpsvLNSMGTCYNELGDEQSAEKFFGKAIG-ENHVN-SYLTMAHLKIRQNRSFEVEN 640
Cdd:TIGR00990 310 YEEAARAFEKALDLGklGEKEAIA---LNLRGTFKCLKGKHLEALADLSKSIElDPRVTqSYIKRASMNLELGDPDKAEE 386

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   641 LLRKAMTLAPESVTVLQNIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNS 720
Cdd:TIGR00990 387 DFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPEA 466

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 17560436   721 YAAHANYGAILHLNQKYDLALKEYEIALILDPTSD 755
Cdd:TIGR00990 467 PDVYNYYGELLLDQNKFDEAIEKFDTAIELEKETK 501
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 656-772 1.25e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 57.66  E-value: 1.25e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 656 LQNIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSYAAHANYGAILHLNQ 735
Cdd:COG5010  23 LVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSG 102

                        90       100       110
                ....*....|....*....|....*....|....*..
gi 17560436 736 KYDLALKEYEIALILDPTSDVARENRKKVIRILRRKR 772
Cdd:COG5010 103 DKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDD 139
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 631-718 1.66e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 57.28  E-value: 1.66e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 631 RQNRSFEVENLLRKAMTLAPESVTVLQNIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFY 710
Cdd:COG5010  66 KLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAAL 145


                ....*...
gi 17560436 711 RKVMEAQP 718
Cdd:COG5010 146 QRALGTSP 153
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
680-761 3.41e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 58.09  E-value: 3.41e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 680 LHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSYAAHANYGAILHLNQKYDLALKEYEIALILDPTSDVARE 759
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80


                ..
gi 17560436 760 NR 761
Cdd:COG0457  81 NL 82
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 596-684 3.55e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 56.51  E-value: 3.55e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 596 CYNELGDEQSAEKFFGKAI--GENHVNSYLTMAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIALAEFHMQNYNRSL 673
Cdd:COG5010  63 LYNKLGDFEESLALLEQALqlDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAK 142

                        90
                ....*....|.
gi 17560436 674 LFYRKALHLDP 684
Cdd:COG5010 143 AALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
630-722 8.00e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 53.64  E-value: 8.00e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 630 IRQNRSFEVENLLRKAMTLAPESVTVLQNIALAEFHMQNYNRSLLFyRKALHLDPTHLDSLQGIANLLQQTQNHVESETF 709
Cdd:COG3063   3 LKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALAY 81

                        90
                ....*....|...
gi 17560436 710 YRKVMEAQPNSYA 722
Cdd:COG3063  82 LERALELDPSALR 94
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 410-578 9.87e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.85  E-value: 9.87e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 410 IRTMQRVDDWKTEESLFKSALEVNPT--KANMNLGYVYTTQKKYELAKYHYRQALKRQGNLADAWYNLGiltsktsnnsn 487
Cdd:COG3914  85 ALLLQALGRYEEALALYRRALALNPDnaEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLG----------- 153

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 488 gsihcyqMALQSRstyaaahlnlalllhdaGHHMAAFSHLDKCLNNTGEFLKFYhvnrktqatcaFNKGRLLQKSGNFHV 567
Cdd:COG3914 154 -------EALRRL-----------------GRLEEAIAALRRALELDPDNAEAL-----------NNLGNALQDLGRLEE 198

                       170
                ....*....|.
gi 17560436 568 AIENFELALKL 578
Cdd:COG3914 199 AIAAYRRALEL 209
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 658-753 2.57e-08

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 55.42  E-value: 2.57e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   658 NIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSYAAHANYGAILHLNQKY 737
Cdd:TIGR02521  36 QLALGYLEQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYGTFLCQQGKY 115

                          90
                  ....*....|....*.
gi 17560436   738 DLALKEYEIAlILDPT 753
Cdd:TIGR02521 116 EQAMQQFEQA-IEDPL 130
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 642-757 6.68e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 56.25  E-value: 6.68e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   642 LRKAMTLAPESVTVLQNIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSY 721
Cdd:TIGR02917 624 FKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAA 703

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 17560436   722 AAHANYGAIlHLNQK-YDLALKEYEIALILDPTSDVA 757
Cdd:TIGR02917 704 LGFELEGDL-YLRQKdYPAAIQAYRKALKRAPSSQNA 739
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
647-755 8.35e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 53.77  E-value: 8.35e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 647 TLAPESVTVLQNIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSYAAHAN 726
Cdd:COG4785  67 LALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLN 146

                        90       100
                ....*....|....*....|....*....
gi 17560436 727 YGAILHLNQKYDLALKEYEIALILDPTSD 755
Cdd:COG4785 147 RGIALYYLGRYELAIADLEKALELDPNDP 175
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 656-774 1.63e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 55.00  E-value: 1.63e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 656 LQNIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSYAAHANYGAILHLNQ 735
Cdd:COG3914  47 LLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALG 126

                        90       100       110
                ....*....|....*....|....*....|....*....
gi 17560436 736 KYDLALKEYEIALILDPTSDVARENRkkvIRILRRKRNL 774
Cdd:COG3914 127 RLEEALAALRRALALNPDFAEAYLNL---GEALRRLGRL 162
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 441-760 2.83e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 54.32  E-value: 2.83e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   441 LGYVYTTQKKYELAKYHYRQALKRQGNLADAWYNLGILTSKTsNNSNGSIHCYQMALQSRSTYAAAHLNLALLLHDAGHH 520
Cdd:TIGR02917 471 LGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQE-GNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNE 549

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   521 MAAFSHLDKC--LNNTGEFLKF----YHV--NRKTQATCAFN---------------KGRLLQKSGNFHVAIENFELALK 577
Cdd:TIGR02917 550 EEAVAWLEKAaeLNPQEIEPALalaqYYLgkGQLKKALAILNeaadaapdspeawlmLGRAQLAAGDLNKAVSSFKKLLA 629

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   578 LGGPHfehtpsvlnsmGTCYNELGDEQSAEKFFGKAIGE---------NHVNSYLTMAHLKIRQNRSFEVENLLR---KA 645
Cdd:TIGR02917 630 LQPDS-----------ALALLLLADAYAVMKNYAKAITSlkralelkpDNTEAQIGLAQLLLAAKRTESAKKIAKslqKQ 698

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   646 MTLAPESVTVLQNIALAEfhmQNYNRSLLFYRKALHLDPTHlDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSYAAHA 725
Cdd:TIGR02917 699 HPKAALGFELEGDLYLRQ---KDYPAAIQAYRKALKRAPSS-QNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRT 774

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 17560436   726 NYGAILHLNQKYDLALKEYEIALILDPTSDVAREN 760
Cdd:TIGR02917 775 ALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNN 809
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 414-531 4.61e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.81  E-value: 4.61e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 414 QRVDDWKTEESLFKSALEVNPT--KANMNLGYVYTTQKKYELAKYHYRQALKRQGNLADAWYNLGILTSKtSNNSNGSIH 491
Cdd:COG4783  15 LLAGDYDEAEALLEKALELDPDnpEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK-AGDYDEALA 93

                        90       100       110       120
                ....*....|....*....|....*....|....*....|
gi 17560436 492 CYQMALQSRSTYAAAHLNLALLLHDAGHHMAAFSHLDKCL 531
Cdd:COG4783  94 LLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKAL 133
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 423-478 5.78e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 49.96  E-value: 5.78e-07
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 17560436 423 ESLFKSALEVNPT--KANMNLGYVYTTQKKYELAKYHYRQALKRQGNLADAWYNLGIL 478
Cdd:COG5010  74 LALLEQALQLDPNnpELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAAL 131
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
558-688 6.14e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 48.24  E-value: 6.14e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 558 LLQKSGNFHVAIENFELALKLGgPHFehtPSVLNSMGTCYNELGDEQSAEKFfgkaigenhvnsyltmahlkirqnrsfe 637
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELD-PDN---ADALNNLGLLLLEQGRYDEAIAL---------------------------- 48

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 17560436 638 venllRKAMTLAPESVTVLQNIALAEFHMQNYNRSLLFYRKALHLDPTHLD 688
Cdd:COG3063  49 -----EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPSALR 94
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 451-663 7.65e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 52.69  E-value: 7.65e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 451 YELAKYHYRQALKRQGNLAdAWYNLGILTSKTSNNSNGSIHCYQMALQSRSTYAAAHLNLALLLHDAGHHMAAFSHLDKC 530
Cdd:COG3914  60 LALAAGEAAAAAAALLLLA-ALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRA 138

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 531 LNNTGEFLKFYHvnrktqatcafNKGRLLQKSGNFHVAIENFELALKLgGPHFehtPSVLNSMGTCYNELGDEQSAEKFF 610
Cdd:COG3914 139 LALNPDFAEAYL-----------NLGEALRRLGRLEEAIAALRRALEL-DPDN---AEALNNLGNALQDLGRLEEAIAAY 203

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 17560436 611 GKAI----GENHVNSYLTMAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIALAE 663
Cdd:COG3914 204 RRALeldpDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSELSPFALLYLPD 260
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 593-752 1.04e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.39  E-value: 1.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   593 MGTCYNELGDEQSAEKFFGKAI----GENHVNSYLTMAHLKIRQNRsfEVENLLRKAMTLA-PESVTVLQNIALAEFHMQ 667
Cdd:TIGR02917  62 LGKIYLALGDYAAAEKELRKALslgyPKNQVLPLLARAYLLQGKFQ--QVLDELPGKTLLDdEGAAELLALRGLAYLGLG 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   668 NYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSYAAHANYGAILHLNQKYDLALKEYEIA 747
Cdd:TIGR02917 140 QLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKA 219


                  ....*
gi 17560436   748 LILDP 752
Cdd:TIGR02917 220 IALRP 224
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 556-748 1.12e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.39  E-value: 1.12e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   556 GRLLQKSGNFHVAIENFELALKLGGPHFEHTP---SVLNSMGTcYNELGDEqSAEKFFGKAIGENHVNSYLTMAHLKIRQ 632
Cdd:TIGR02917  63 GKIYLALGDYAAAEKELRKALSLGYPKNQVLPllaRAYLLQGK-FQQVLDE-LPGKTLLDDEGAAELLALRGLAYLGLGQ 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   633 NRsfEVENLLRKAMTLAP---ESVTVLQNIALAEFhmqNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETF 709
Cdd:TIGR02917 141 LE--LAQKSYEQALAIDPrslYAKLGLAQLALAEN---RFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAA 215

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 17560436   710 YRKVMEAQPNSYAAHANYGAILHLNQKYDLALKEYEIAL 748
Cdd:TIGR02917 216 YRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALL 254
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
696-761 1.16e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 47.47  E-value: 1.16e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 17560436 696 LLQQTQNHVESETFYRKVMEAQPNSYAAHANYGAILHLNQKYDLALkEYEIALILDPTSDVARENR 761
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNL 65
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 571-715 1.25e-06

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 51.09  E-value: 1.25e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 571 NFELALKLGGPHFEHTPS---VLNSMGTCYNELGDEQSAEKFFGKAI----GENHVnSYLTMAHLKIRQN--RSFE--VE 639
Cdd:cd24142  15 NFELALKFLQRALELEPNnveALELLGEILLELGDVEEAREVLLRAIeldpDGGYE-KYLYLGQLSGGEEalQYYEkgIE 93

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 640 NLLRKAMTL------APESVTVLQN------IALAEFHM----------QNYNRSLlfyRKALHLDPTHLDSLQGIANLL 697
Cdd:cd24142  94 ILEEELQALqaasaeAEEEAEELKRklssalCALAEIYMtdlcdepdaeQRCEELI---TKALELDPTNPEALQTLASLR 170

                       170
                ....*....|....*...
gi 17560436 698 QQTQNHVESETFYRKVME 715
Cdd:cd24142 171 ISQQRPDEAKEALRRSLE 188
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
414-478 1.52e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 47.09  E-value: 1.52e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17560436 414 QRVDDWKTEESLFKSALEVNP--TKANMNLGYVYTTQKKYELAKyHYRQALKRQGNLADAWYNLGIL 478
Cdd:COG3063   3 LKLGDLEEAEEYYEKALELDPdnADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAEL 68
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 427-662 1.59e-06

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 50.03  E-value: 1.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   427 KSALEVNPT--KANMNLGYVYTTQKKYELAKYHYRQALkrqgnladawynlgiltskTSNNSNGSIHcyqmalqsrstya 504
Cdd:TIGR02521  55 DKALEHDPDdyLAYLALALYYQQLGELEKAEDSFRRAL-------------------TLNPNNGDVL------------- 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   505 aahlnlalllhdaghhmaafshldkclNNTGEFLkfyhvnrktqatCafnkgrllqKSGNFHVAIENFELALKLggPHFE 584
Cdd:TIGR02521 103 ---------------------------NNYGTFL------------C---------QQGKYEQAMQQFEQAIED--PLYP 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   585 HTPSVLNSMGTCYNELGDEQSAEKFFGKAIGENHVN--SYLTMAHLKIRQNRSFEVENLLRKAMTLA---PESVTVLQNI 659
Cdd:TIGR02521 133 QPARSLENAGLCALKAGDFDKAEKYLTRALQIDPQRpeSLLELAELYYLRGQYKDARAYLERYQQTYnqtAESLWLGIRI 212


                  ...
gi 17560436   660 ALA 662
Cdd:TIGR02521 213 ARA 215
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 687-761 2.32e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.88  E-value: 2.32e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17560436 687 LDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSYAAHANYGAILHLNQKYDLALKEYEIALILDPTSDVARENR 761
Cdd:COG4783   4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNL 78
TPR_12 pfam13424
Tetratricopeptide repeat;
554-614 1.54e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 43.53  E-value: 1.54e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17560436   554 NKGRLLQKSGNFHVAIENFELAL----KLGGPHFEHTPSVLNSMGTCYNELGDEQSAEKFFGKAI 614
Cdd:pfam13424   8 NLAAVLRRLGRYDEALELLEKALeiarRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERAL 72
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 426-532 3.52e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 44.23  E-value: 3.52e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 426 FKSALEVNP--TKANMNLGYVYTTQKKYELAKYHYRQALKRQGNLADAWYNLGILTSKtSNNSNGSIHCYQMALQSRSTY 503
Cdd:COG4235   6 LRQALAANPndAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLA-AGDTEEAEELLERALALDPDN 84

                        90       100
                ....*....|....*....|....*....
gi 17560436 504 AAAHLNLALLLHDAGHHMAAFSHLDKCLN 532
Cdd:COG4235  85 PEALYLLGLAAFQQGDYAEAIAAWQKLLA 113
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 441-748 3.91e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.39  E-value: 3.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   441 LGYVYTTQKKYELAKYHYRQALKRQGNLADAWYNLgILTSKTSNNSNGSIHCYQMALQSRSTYAAAHLNlalllhdaghh 520
Cdd:TIGR02917 607 LGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLL-ADAYAVMKNYAKAITSLKRALELKPDNTEAQIG----------- 674

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   521 MAAFSHLDKCLNNTGEFLKFYHVNRKTQATCAFNKGRLLQKSGNFHVAIENFELALKLggphfehTPSVLNSM--GTCYN 598
Cdd:TIGR02917 675 LAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKR-------APSSQNAIklHRALL 747

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   599 ELGDEQSAEK----FFGKAIGENHVNSYLtmAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIALAEfhMQNYN-RSL 673
Cdd:TIGR02917 748 ASGNTAEAVKtleaWLKTHPNDAVLRTAL--AELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLY--LELKDpRAL 823

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17560436   674 LFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSYAAHANYGAILHLNQKYDLALKEYEIAL 748
Cdd:TIGR02917 824 EYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEARKELDKLL 898
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 437-617 7.34e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 43.26  E-value: 7.34e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 437 ANMNLGYVYTTQKKYELAKYHYRQALKRQGNLADAWYNLGiltsktsnnsngsiHCYQMAlqsrstyaaahlnlalllhd 516
Cdd:COG4783   6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLG--------------EILLQL-------------------- 51

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 517 aGHHMAAFSHLDKCLNNTGEFLKFYhvnrktqatcaFNKGRLLQKSGNFHVAIENFELALKLGGPHfehtPSVLNSMGTC 596
Cdd:COG4783  52 -GDLDEAIVLLHEALELDPDEPEAR-----------LNLGLALLKAGDYDEALALLEKALKLDPEH----PEAYLRLARA 115

                       170       180
                ....*....|....*....|.
gi 17560436 597 YNELGDEQSAEKFFGKAIGEN 617
Cdd:COG4783 116 YRALGRPDEAIAALEKALELD 136
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 410-577 1.12e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 44.72  E-value: 1.12e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 410 IRTMQRVDDWKTEESLFKSALEVNPTKAN--MNLGYVYTTQKKYELAKYHYRQALKRQGNLADAWYNLGILTSKTsNNSN 487
Cdd:COG2956 117 AEIYEQEGDWEKAIEVLERLLKLGPENAHayCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQ-GDYE 195

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 488 GSIHCYQMALQSRSTYAAAHLNLALLLHDAGHHMAAFSHLDKCLnntgeflkfyhvNRKTQATCAFNKGRLLQKSGNFHV 567
Cdd:COG2956 196 EAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKAL------------ELDPSDDLLLALADLLERKEGLEA 263

                       170
                ....*....|
gi 17560436 568 AIENFELALK 577
Cdd:COG2956 264 ALALLERQLR 273
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
710-761 1.19e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 44.14  E-value: 1.19e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|..
gi 17560436 710 YRKVMEAQPNSYAAHANYGAILHLNQKYDLALKEYEIALILDPTSDVARENR 761
Cdd:COG4785  96 FDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNR 147
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 557-752 1.99e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.07  E-value: 1.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   557 RLLQKSGNFHVAIENFELALKLGGPHFEhtpSVLNSMGTCYNELGDEQSAEKFFGKAIGENHVNSY--LTMAHLKIRQNR 634
Cdd:TIGR02917  98 RAYLLQGKFQQVLDELPGKTLLDDEGAA---ELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYakLGLAQLALAENR 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   635 SFEVENLLRKAMTLAPESVTVLQNIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVM 714
Cdd:TIGR02917 175 FDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALL 254

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 17560436   715 EAQPNSYAAHaNYGAILHLNQK-YDLALKEYEIALILDP 752
Cdd:TIGR02917 255 KKAPNSPLAH-YLKALVDFQKKnYEDARETLQDALKSAP 292
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 661-767 2.73e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.13  E-value: 2.73e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 661 LAEFHMQNYNRSLLFYRKALHLDPTHL---DSLQGIANLLQQTQNHVESETFYRKVMEAQPNS-YAAHANY--GAILHLN 734
Cdd:COG1729   1 KALLKAGDYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSpKAPDALLklGLSYLEL 80

                        90       100       110
                ....*....|....*....|....*....|...
gi 17560436 735 QKYDLALKEYEIALILDPTSDVARENRKKVIRI 767
Cdd:COG1729  81 GDYDKARATLEELIKKYPDSEAAKEARARLARL 113
TPR_11 pfam13414
TPR repeat;
442-478 4.07e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 38.61  E-value: 4.07e-04
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 17560436   442 GYVYTTQKKYELAKYHYRQALKRQGNLADAWYNLGIL 478
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLA 37
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
594-686 4.47e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 42.59  E-value: 4.47e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 594 GTCYNELGDEQSAEKFFGKAIGENHVNS--YLTMAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIALAEFHMQNYNR 671
Cdd:COG4785  80 GVAYDSLGDYDLAIADFDQALELDPDLAeaYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYEL 159

                        90
                ....*....|....*
gi 17560436 672 SLLFYRKALHLDPTH 686
Cdd:COG4785 160 AIADLEKALELDPND 174
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 556-663 5.17e-04

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 43.07  E-value: 5.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436   556 GRLLQKSGNFHVAIENFELALKLGG-PHFEHTPSV---LNSMGTCYNELGDEQSAEKFFGKAI-----GENH--VNSYLT 624
Cdd:pfam17874  87 GEILRAQGRLHQALETYQQALQLARdHGLQHLPLHgflLVGLADLLYEWNDLEEAEQHAQQGIqlgrqWEPDaaVDAYVL 166

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 17560436   625 MAHLKIRQNRSFEVENLLRKAMTLAPESVTVLQNIALAE 663
Cdd:pfam17874 167 LARIALAQGELEEALTLLRRAELLARQSFFHVDWLANAE 205
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
444-539 6.71e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.38  E-value: 6.71e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 444 VYTTQKKYELAKYHYRQALKRQGNLADAWYNLGILTSKTSNNSNGSIhcYQMALQSRSTYAAAHLNLALLLHDAGHHMAA 523
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA--LEKALKLDPNNAEALLNLAELLLELGDYDEA 78

                        90
                ....*....|....*.
gi 17560436 524 FSHLDKCLNNTGEFLK 539
Cdd:COG3063  79 LAYLERALELDPSALR 94
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
433-477 8.23e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 41.82  E-value: 8.23e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*..
gi 17560436 433 NPTKANM--NLGYVYTTQKKYELAKYHYRQALKRQGNLADAWYNLGI 477
Cdd:COG4785  69 LPDLAQLyyERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGL 115
TPR_19 pfam14559
Tetratricopeptide repeat;
668-730 1.04e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 37.95  E-value: 1.04e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17560436   668 NYNRSLLFYRKALHLDPTHLDSLQGIANLLQQTQNHVESETFYRKVMEAQPNSYAAHANYGAI 730
Cdd:pfam14559   3 DYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 415-478 3.84e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.66  E-value: 3.84e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17560436 415 RVDDWKTEESLFKSALEVNPT-----KANMNLGYVYTTQKKYELAKYHYRQALKRQGN---LADAWYNLGIL 478
Cdd:COG1729   5 KAGDYDEAIAAFKAFLKRYPNsplapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLS 76
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 631-723 4.15e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.66  E-value: 4.15e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560436 631 RQNRSFEVENLLRKAMTLAPESVTVLQ---NIALAEFHMQNYNRSLLFYRKALHLDPTH---LDSLQGIANLLQQTQNHV 704
Cdd:COG1729   5 KAGDYDEAIAAFKAFLKRYPNSPLAPDalyWLGEAYYALGDYDEAAEAFEKLLKRYPDSpkaPDALLKLGLSYLELGDYD 84

                        90
                ....*....|....*....
gi 17560436 705 ESETFYRKVMEAQPNSYAA 723
Cdd:COG1729  85 KARATLEELIKKYPDSEAA 103
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 655-686 5.22e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.11  E-value: 5.22e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 17560436    655 VLQNIALAEFHMQNYNRSLLFYRKALHLDPTH 686
Cdd:smart00028   3 ALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 423-464 5.55e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 37.68  E-value: 5.55e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....
gi 17560436 423 ESLFKSALEVNPT--KANMNLGYVYTTQKKYELAKYHYRQALKR 464
Cdd:COG4235  71 EELLERALALDPDnpEALYLLGLAAFQQGDYAEAIAAWQKLLAL 114
TPR_1 pfam00515
Tetratricopeptide repeat;
655-686 7.80e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.70  E-value: 7.80e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 17560436   655 VLQNIALAEFHMQNYNRSLLFYRKALHLDPTH 686
Cdd:pfam00515   3 ALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_1 pfam00515
Tetratricopeptide repeat;
436-467 9.69e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.32  E-value: 9.69e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 17560436   436 KANMNLGYVYTTQKKYELAKYHYRQALKRQGN 467
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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