NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|17540574|ref|NP_502700|]
View 

Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans]

Protein Classification

cuticular collagen family protein( domain architecture ID 13931766)

cuticular collagen family protein is a structural macromolecule of the extracellular matrix containing triple helix domains that form tight interactions and stabilize supramolecular aggregates

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
12-64 4.32e-20

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


:

Pssm-ID: 198156  Cd Length: 53  Bit Score: 81.74  E-value: 4.32e-20
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 17540574     12 FVAYSAVTFSVVAVFSLCITLPLVYNYVDGIKTQINHEIKFCKHSARDIFAEV 64
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
PRK07764 super family cl35613
DNA polymerase III subunits gamma and tau; Validated
89-281 6.19e-04

DNA polymerase III subunits gamma and tau; Validated


The actual alignment was detected with superfamily member PRK07764:

Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.51  E-value: 6.19e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17540574   89 VDQGSEGAQGGSCSGCCLPGAAGPAGTPGKPGRPGRPGAAGLPGNPGRPPAQPCEPITPPPCKPCPQGPAGAPGAPGPQG 168
Cdd:PRK07764 588 VGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGD 667
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17540574  169 DAGAP-GAPGQGSGAGAPGPAGPKGASGAPGNPGQAGAPGQPGADAQSESIPGAPGQAGPQGPPGPAGSPGAPGGPGQPG 247
Cdd:PRK07764 668 GWPAKaGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDD 747
                        170       180       190
                 ....*....|....*....|....*....|....
gi 17540574  248 APGQKGPSGAPGQPGADGNPGAPGQPGQAGGAGE 281
Cdd:PRK07764 748 PPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSE 781
 
Name Accession Description Interval E-value
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
12-64 4.32e-20

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 198156  Cd Length: 53  Bit Score: 81.74  E-value: 4.32e-20
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 17540574     12 FVAYSAVTFSVVAVFSLCITLPLVYNYVDGIKTQINHEIKFCKHSARDIFAEV 64
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
Col_cuticle_N pfam01484
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
15-64 7.90e-17

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens, see pfam01391. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 460226  Cd Length: 50  Bit Score: 72.88  E-value: 7.90e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 17540574    15 YSAVTFSVVAVFSLCITLPLVYNYVDGIKTQINHEIKFCKHSARDIFAEV 64
Cdd:pfam01484   1 YVAVAFSTVAILSSLITLPSIYNDIQELQSEVLDEMDEFKARSDDAWNEM 50
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
89-281 6.19e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.51  E-value: 6.19e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17540574   89 VDQGSEGAQGGSCSGCCLPGAAGPAGTPGKPGRPGRPGAAGLPGNPGRPPAQPCEPITPPPCKPCPQGPAGAPGAPGPQG 168
Cdd:PRK07764 588 VGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGD 667
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17540574  169 DAGAP-GAPGQGSGAGAPGPAGPKGASGAPGNPGQAGAPGQPGADAQSESIPGAPGQAGPQGPPGPAGSPGAPGGPGQPG 247
Cdd:PRK07764 668 GWPAKaGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDD 747
                        170       180       190
                 ....*....|....*....|....*....|....
gi 17540574  248 APGQKGPSGAPGQPGADGNPGAPGQPGQAGGAGE 281
Cdd:PRK07764 748 PPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSE 781
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
107-265 1.33e-03

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 39.89  E-value: 1.33e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17540574  107 PGAAGPAGTPGKPGRPGRPGAAGLPGNPGRPPAQPCEPITPPPCKPCPQGPAGAPGAPGPQGDAGAPGAPGQGSGAGAPG 186
Cdd:NF038329 122 PGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETG 201
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17540574  187 PAGPKGASGAPGNPGQAGAPGQPGADAQSESIP----------GAPGQAGPQGPPGPAGSPGAPGGPGQPGAPGQKGPSG 256
Cdd:NF038329 202 PAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQqgpdgdpgptGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERG 281

                 ....*....
gi 17540574  257 APGQPGADG 265
Cdd:NF038329 282 PVGPAGKDG 290
 
Name Accession Description Interval E-value
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
12-64 4.32e-20

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 198156  Cd Length: 53  Bit Score: 81.74  E-value: 4.32e-20
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 17540574     12 FVAYSAVTFSVVAVFSLCITLPLVYNYVDGIKTQINHEIKFCKHSARDIFAEV 64
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
Col_cuticle_N pfam01484
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
15-64 7.90e-17

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens, see pfam01391. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 460226  Cd Length: 50  Bit Score: 72.88  E-value: 7.90e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 17540574    15 YSAVTFSVVAVFSLCITLPLVYNYVDGIKTQINHEIKFCKHSARDIFAEV 64
Cdd:pfam01484   1 YVAVAFSTVAILSSLITLPSIYNDIQELQSEVLDEMDEFKARSDDAWNEM 50
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
89-281 6.19e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.51  E-value: 6.19e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17540574   89 VDQGSEGAQGGSCSGCCLPGAAGPAGTPGKPGRPGRPGAAGLPGNPGRPPAQPCEPITPPPCKPCPQGPAGAPGAPGPQG 168
Cdd:PRK07764 588 VGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGD 667
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17540574  169 DAGAP-GAPGQGSGAGAPGPAGPKGASGAPGNPGQAGAPGQPGADAQSESIPGAPGQAGPQGPPGPAGSPGAPGGPGQPG 247
Cdd:PRK07764 668 GWPAKaGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDD 747
                        170       180       190
                 ....*....|....*....|....*....|....
gi 17540574  248 APGQKGPSGAPGQPGADGNPGAPGQPGQAGGAGE 281
Cdd:PRK07764 748 PPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSE 781
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
107-265 1.33e-03

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 39.89  E-value: 1.33e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17540574  107 PGAAGPAGTPGKPGRPGRPGAAGLPGNPGRPPAQPCEPITPPPCKPCPQGPAGAPGAPGPQGDAGAPGAPGQGSGAGAPG 186
Cdd:NF038329 122 PGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETG 201
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17540574  187 PAGPKGASGAPGNPGQAGAPGQPGADAQSESIP----------GAPGQAGPQGPPGPAGSPGAPGGPGQPGAPGQKGPSG 256
Cdd:NF038329 202 PAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQqgpdgdpgptGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERG 281

                 ....*....
gi 17540574  257 APGQPGADG 265
Cdd:NF038329 282 PVGPAGKDG 290
PHA03247 PHA03247
large tegument protein UL36; Provisional
92-218 6.01e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 38.38  E-value: 6.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17540574    92 GSEGAQGGSCSGCCLPGAAGPAGTPGKPGRPGRPGAAGLPGNPGRpPAQPCEPITPPP---CKPCPQGPAGAPGAPGPQG 168
Cdd:PHA03247 2724 GPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPA-PAPPAAPAAGPPrrlTRPAVASLSESRESLPSPW 2802
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 17540574   169 DAGAPGAPGQGSGAGAPGPAGPKGASGAPGNPGQAGAPGQPGADAQSESI 218
Cdd:PHA03247 2803 DPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPL 2852
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH