Bromodomain associated domain-containing protein [Caenorhabditis elegans]
List of domain hits
Name | Accession | Description | Interval | E-value | |||
HFD_SF super family | cl45933 | histone fold domain (HFD) superfamily; The histone fold domain (HFD) is a structurally ... |
11-95 | 6.57e-07 | |||
histone fold domain (HFD) superfamily; The histone fold domain (HFD) is a structurally conserved interaction motif involved in heterodimerization of the core histones and their assembly into the nucleosome octamer. Histone fold heterodimers play crucial roles in gene regulation. The minimal HFD consists of three alpha helices connected by two short, unstructured loops. The HFD is found in core histones, TATA box-binding protein-associated factors (TAFs), and many other transcription factors. HFD plays a role in the nucleosomal core particle by conserving histone interactions; these contain more than one HFD. The structure of the nucleosome core particle has two modes that have the largest interaction surfaces, and these are the H3-H4 and H2A-H2B heterodimer interactions. Several TAFs interact via histone-fold (HF) motifs. Five HF-containing TAF pairs have been described in transcription factor II D (TFIID): TAF6-TAF9, TAF4-TAF12, TAF11-TAF13, TAF8-TAF10 and TAF3-TAF10. The actual alignment was detected with superfamily member cd22916: Pssm-ID: 480273 Cd Length: 92 Bit Score: 47.21 E-value: 6.57e-07
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Name | Accession | Description | Interval | E-value | |||
HFD_TAF3 | cd22916 | histone-fold domain found in transcription initiation factor TFIID subunit 3 (TAF3) and ... |
11-95 | 6.57e-07 | |||
histone-fold domain found in transcription initiation factor TFIID subunit 3 (TAF3) and similar proteins; TAF3, also called TATA Binding Protein (TBP) associated factor 3, 140 kDa TATA box-binding protein-associated factor, TBP-associated factor 3, or transcription initiation factor TFIID 140 kDa subunit (TAF(II)140, TAF140, TAFII-140,TAFII140), is a component of the TFIID complex that is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). TFIID is one of the general transcription factors required for accurate and regulated initiation by RNA polymerase II. It plays a central role in mediating promoter responses to various activators and repressors. Pssm-ID: 467041 Cd Length: 92 Bit Score: 47.21 E-value: 6.57e-07
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Name | Accession | Description | Interval | E-value | |||
HFD_TAF3 | cd22916 | histone-fold domain found in transcription initiation factor TFIID subunit 3 (TAF3) and ... |
11-95 | 6.57e-07 | |||
histone-fold domain found in transcription initiation factor TFIID subunit 3 (TAF3) and similar proteins; TAF3, also called TATA Binding Protein (TBP) associated factor 3, 140 kDa TATA box-binding protein-associated factor, TBP-associated factor 3, or transcription initiation factor TFIID 140 kDa subunit (TAF(II)140, TAF140, TAFII-140,TAFII140), is a component of the TFIID complex that is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). TFIID is one of the general transcription factors required for accurate and regulated initiation by RNA polymerase II. It plays a central role in mediating promoter responses to various activators and repressors. Pssm-ID: 467041 Cd Length: 92 Bit Score: 47.21 E-value: 6.57e-07
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Blast search parameters | ||||
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