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Conserved domains on  [gi|133903949|ref|NP_494821|]
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Rootletin [Caenorhabditis elegans]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 568-1297 6.50e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 107.06  E-value: 6.50e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   568 LDMLETERDELKKKLETEREQADQrdleiaecrakldemAEKEAELRKELAEFQAIITAMEgegklnqeqFLESKNELNT 647
Cdd:TIGR02168  188 LDRLEDILNELERQLKSLERQAEK---------------AERYKELKAELRELELALLVLR---------LEELREELEE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   648 LTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANE 727
Cdd:TIGR02168  244 LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   728 KYDDAARKNDALLEDVATWQEKYEQLKME-------LEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKqkgvtvd 800
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEEKLEELKEElesleaeLEELEAELEELESRLEELEEQLETLRSKVAQLELQIA------- 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   801 SLNEEISSLKEQLNKSEKERkeellrmeeleqKNEAEMKEEYEVKLQLAEKDRqgvenfgkecearmneltkiHEMLMEE 880
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRR------------ERLQQEIEELLKKLEEAELKE--------------------LQAELEE 444

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   881 HDQLKVDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRLESSKNeavteLQERVQKLEDVVKEKEDK----- 955
Cdd:TIGR02168  445 LEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER-----LQENLEGFSEGVKALLKNqsgls 519

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   956 --------------------EIALRRDLE----DSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEE 1011
Cdd:TIGR02168  520 gilgvlselisvdegyeaaiEAALGGRLQavvvENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEG 599

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1012 AMLVATKH--------------------ATTIDQQTR---------RISVLEGDV-----------EKLTAGIAERESSI 1051
Cdd:TIGR02168  600 FLGVAKDLvkfdpklrkalsyllggvlvVDDLDNALElakklrpgyRIVTLDGDLvrpggvitggsAKTNSSILERRREI 679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1052 NALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERK-------KIQDLADQLREANKVVHNM 1124
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKdlarleaEVEQLEERIAQLSKELTEL 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1125 RMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNEQFRLTDLEKVRKALQDE 1204
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERR 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1205 NQRLVNDLATVK---AAFEVKRETSKSAISDILDKYRSAEEKANKGELDNQRLRSDLATVTLKLERQELKAKDSDNRLRD 1281
Cdd:TIGR02168  840 LEDLEEQIEELSediESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE 919

                          810
                   ....*....|....*.
gi 133903949  1282 SQKRFEEVQSKLANLQ 1297
Cdd:TIGR02168  920 LREKLAQLELRLEGLE 935
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
162-282 7.29e-23

Ciliary rootlet component, centrosome cohesion;


:

Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 97.80  E-value: 7.29e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   162 EENLDELFAKLKEELFKNNTLEEVNEMLREENDAALAANEHLRVDATNLSRQLQQLQQQQHTESMRFRSENTRYRNQTET 241
Cdd:pfam15035   70 SADLEEALIRLEEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSS 149

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 133903949   242 QHRKLISLWKEFTAVKRQLHELRTTTANDLDRQLTEFTRCA 282
Cdd:pfam15035  150 EHSRLLSLWREVVAVRRQFTELKTATERDLSELKTEFSRTS 190
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1029-1791 9.92e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.57  E-value: 9.92e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1029 RISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAELEKLKDELavmlkqnSELKNGKEGLSEKWNEERKKIQ 1108
Cdd:TIGR02168  226 ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV-------SELEEEIEELQKELYALANEIS 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1109 DLADQLREANKVVHNMRMKNV-------NLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSML 1181
Cdd:TIGR02168  299 RLEQQKQILRERLANLERQLEeleaqleELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1182 KQAQNEQFRLTDLEKVRKALQDENQRLVNDLAtvkaAFEVKRETSKSAISDILDKYRSAEEKANKGELDnqRLRSDLATV 1261
Cdd:TIGR02168  379 EQLETLRSKVAQLELQIASLNNEIERLEARLE----RLEDRRERLQQEIEELLKKLEEAELKELQAELE--ELEEELEEL 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1262 TLKLERQELKAKDSDNRLRDSQKRFEEVQSKLANLQ--KSAVESLQNPMSSNSR------QNRSIYVDIP---------- 1323
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQALDAAERELAQLQarLDSLERLQENLEGFSEgvkallKNQSGLSGILgvlselisvd 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1324 ---RAASSIGLNENSDEVPLRSSPSVRFADSS--QNMQRAVDSMDVSSSVGVTLRFLKERIEQLEADNADLSDALEKAKD 1398
Cdd:TIGR02168  533 egyEAAIEAALGGRLQAVVVENLNAAKKAIAFlkQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDP 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1399 ELRQRNEKLADRQMVIERVER--QLVHITEERNTIenrmtSQRQMYLTNEESSRSREHEirsmKARISTLElhlreKESK 1476
Cdd:TIGR02168  613 KLRKALSYLLGGVLVVDDLDNalELAKKLRPGYRI-----VTLDGDLVRPGGVITGGSA----KTNSSILE-----RRRE 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1477 LAHLRKEIEVLHGQLHDALESKEKAtglvgvqDSKHRDLEEQLDRANRERELAIGKQRRTLAENENLFRKLEQLEKEREQ 1556
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAEL-------RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1557 LMREITDERRLNERNRTSLEELRVSERTWKSAMTTAKKPAEEQERAVQEQRRweesnhemtnRNTALTKECDRLRVEMRD 1636
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE----------ALDELRAELTLLNEEAAN 821

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1637 QLNRMNGINLRSVDFERKNEELSSKLIVMQNTVTAMKKFEEEWKRLEAEMRAELKILRKEKLMQTAEIEDLKRKSFRSDT 1716
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSE 901

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1717 EKKEIEGIRVRLEREISALKRHVDALEEEKGKTE---KAVRETMNER-----RAIDKSLASMERENQQLYRNCAQLQAQI 1788
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLELRLEGLEvriDNLQERLSEEysltlEEAEALENKIEDDEEEARRRLKRLENKI 981


                   ...
gi 133903949  1789 QNL 1791
Cdd:TIGR02168  982 KEL 984
PRK02224 super family cl32023
DNA double-strand break repair Rad50 ATPase;
294-797 6.76e-14

DNA double-strand break repair Rad50 ATPase;


The actual alignment was detected with superfamily member PRK02224:

Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 77.39  E-value: 6.76e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  294 QKNLDQKEQMKREKDDVLD---ETLRQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQL------- 363
Cdd:PRK02224  226 EEQREQARETRDEADEVLEeheERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLlaeagld 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  364 ----SKMAHEMAGGRGRNETPMDVARKMRKLLTTKNGEIDESREAAKQAEKERDrakkdlEKEEKRRKDDREAERKRSSV 439
Cdd:PRK02224  306 dadaEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAE------ELREEAAELESELEEAREAV 379

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  440 ySQREHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQFIEEL-----MIRHREELKEREDSHEEA 514
Cdd:PRK02224  380 -EDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLrtareRVEEAEALLEAGKCPECG 458

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  515 LRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAMKtDLDDKTLRLDMLETERDELKKKLETEREQADQRDL 594
Cdd:PRK02224  459 QPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAE-DLVEAEDRIERLEERREDLEELIAERRETIEEKRE 537

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  595 EIAECRAKLDEMAEKEAELRKELAEF-QAIITAMEGEGKLNQEQF-----LESKNELNTLTDQIESLNSEVENKNEEIRN 668
Cdd:PRK02224  538 RAEELRERAAELEAEAEEKREAAAEAeEEAEEAREEVAELNSKLAelkerIESLERIRTLLAAIADAEDEIERLREKREA 617

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  669 LMATLQEKEVHIQNVRTSSHQLTATYEEANgeIDILKAELTRLHEqvnertrQISEANEKYDDAARKNDALLEDVATWQE 748
Cdd:PRK02224  618 LAELNDERRERLAEKRERKRELEAEFDEAR--IEEAREDKERAEE-------YLEQVEEKLDELREERDDLQAEIGAVEN 688

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 133903949  749 KYEQLKMELEEMNRRGQEKEREEAdLRALLDDLRGNFDKLTNELKQKGV 797
Cdd:PRK02224  689 ELEELEELRERREALENRVEALEA-LYDEAEELESMYGDLRAELRQRNV 736
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 568-1297 6.50e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 107.06  E-value: 6.50e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   568 LDMLETERDELKKKLETEREQADQrdleiaecrakldemAEKEAELRKELAEFQAIITAMEgegklnqeqFLESKNELNT 647
Cdd:TIGR02168  188 LDRLEDILNELERQLKSLERQAEK---------------AERYKELKAELRELELALLVLR---------LEELREELEE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   648 LTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANE 727
Cdd:TIGR02168  244 LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   728 KYDDAARKNDALLEDVATWQEKYEQLKME-------LEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKqkgvtvd 800
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEEKLEELKEElesleaeLEELEAELEELESRLEELEEQLETLRSKVAQLELQIA------- 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   801 SLNEEISSLKEQLNKSEKERkeellrmeeleqKNEAEMKEEYEVKLQLAEKDRqgvenfgkecearmneltkiHEMLMEE 880
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRR------------ERLQQEIEELLKKLEEAELKE--------------------LQAELEE 444

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   881 HDQLKVDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRLESSKNeavteLQERVQKLEDVVKEKEDK----- 955
Cdd:TIGR02168  445 LEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER-----LQENLEGFSEGVKALLKNqsgls 519

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   956 --------------------EIALRRDLE----DSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEE 1011
Cdd:TIGR02168  520 gilgvlselisvdegyeaaiEAALGGRLQavvvENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEG 599

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1012 AMLVATKH--------------------ATTIDQQTR---------RISVLEGDV-----------EKLTAGIAERESSI 1051
Cdd:TIGR02168  600 FLGVAKDLvkfdpklrkalsyllggvlvVDDLDNALElakklrpgyRIVTLDGDLvrpggvitggsAKTNSSILERRREI 679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1052 NALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERK-------KIQDLADQLREANKVVHNM 1124
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKdlarleaEVEQLEERIAQLSKELTEL 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1125 RMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNEQFRLTDLEKVRKALQDE 1204
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERR 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1205 NQRLVNDLATVK---AAFEVKRETSKSAISDILDKYRSAEEKANKGELDNQRLRSDLATVTLKLERQELKAKDSDNRLRD 1281
Cdd:TIGR02168  840 LEDLEEQIEELSediESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE 919

                          810
                   ....*....|....*.
gi 133903949  1282 SQKRFEEVQSKLANLQ 1297
Cdd:TIGR02168  920 LREKLAQLELRLEGLE 935
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
162-282 7.29e-23

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 97.80  E-value: 7.29e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   162 EENLDELFAKLKEELFKNNTLEEVNEMLREENDAALAANEHLRVDATNLSRQLQQLQQQQHTESMRFRSENTRYRNQTET 241
Cdd:pfam15035   70 SADLEEALIRLEEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSS 149

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 133903949   242 QHRKLISLWKEFTAVKRQLHELRTTTANDLDRQLTEFTRCA 282
Cdd:pfam15035  150 EHSRLLSLWREVVAVRRQFTELKTATERDLSELKTEFSRTS 190
PTZ00121 PTZ00121
MAEBL; Provisional
 384-1141 2.23e-17

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 89.43  E-value: 2.23e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  384 ARKMRKLLTTKNGEIDESREAAKQAEKERD-----RAKKDLEKEEKRRKDD-------REAERKRSSVYSQREHDLKKLD 451
Cdd:PTZ00121 1100 AEEAKKTETGKAEEARKAEEAKKKAEDARKaeearKAEDARKAEEARKAEDakrveiaRKAEDARKAEEARKAEDAKKAE 1179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  452 D-----ELRKASEkIRNLEEQRESQEKLTISVQNSLNEAHR-QHKQFIEElmIRHREELKEREDSHEEALRSKDTEERSR 525
Cdd:PTZ00121 1180 AarkaeEVRKAEE-LRKAEDARKAEAARKAEEERKAEEARKaEDAKKAEA--VKKAEEAKKDAEEAKKAEEERNNEEIRK 1256

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  526 FEKERSEREKIR---------RESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETER--DELKKKLETEREQADQRDL 594
Cdd:PTZ00121 1257 FEEARMAHFARRqaaikaeeaRKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKkaDEAKKKAEEAKKKADAAKK 1336

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  595 EiAECRAKLDEMAEKEAELRK---ELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMA 671
Cdd:PTZ00121 1337 K-AEEAKKAAEAAKAEAEAAAdeaEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAA 1415

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  672 T---LQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANE--KYDDAARKNDALLEDVATW 746
Cdd:PTZ00121 1416 AkkkADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEakKKAEEAKKADEAKKKAEEA 1495

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  747 QEKYEQLKMELEEMNRRGQEKEREEAdlrALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSlkEQLNKSEKERKEELLR 826
Cdd:PTZ00121 1496 KKKADEAKKAAEAKKKADEAKKAEEA---KKADEAKKAEEAKKADEAKKAEEKKKADELKKA--EELKKAEEKKKAEEAK 1570

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  827 MEELEQKNEAEMKEEyevkLQLAEKDRQGVENFGKECEARMneltKIHEMLMEEHDQLKVDHLHTEEEVERLKEKMRKEL 906
Cdd:PTZ00121 1571 KAEEDKNMALRKAEE----AKKAEEARIEEVMKLYEEEKKM----KAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKE 1642

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  907 EKLNEQNDGDRAEWSNERNRLESSKNEAvtelQERVQKLEDVVKEKEDKEIALRRDLEDSHEKSRdlDDKLRKMElTDEE 986
Cdd:PTZ00121 1643 AEEKKKAEELKKAEEENKIKAAEEAKKA----EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK--AEELKKKE-AEEK 1715

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  987 KEEDRKKEQKTLNEERMKLMEQKEEAMLVATKHATTIDQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELISKLE 1066
Cdd:PTZ00121 1716 KKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRME 1795

                         730       740       750       760       770       780       790
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 133903949 1067 tTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERKKIQDLADQLREANKVV--HNMRMKNVNLEEKKNELDQN 1141
Cdd:PTZ00121 1796 -VDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFekHKFNKNNENGEDGNKEADFN 1871
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1029-1791 9.92e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.57  E-value: 9.92e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1029 RISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAELEKLKDELavmlkqnSELKNGKEGLSEKWNEERKKIQ 1108
Cdd:TIGR02168  226 ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV-------SELEEEIEELQKELYALANEIS 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1109 DLADQLREANKVVHNMRMKNV-------NLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSML 1181
Cdd:TIGR02168  299 RLEQQKQILRERLANLERQLEeleaqleELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1182 KQAQNEQFRLTDLEKVRKALQDENQRLVNDLAtvkaAFEVKRETSKSAISDILDKYRSAEEKANKGELDnqRLRSDLATV 1261
Cdd:TIGR02168  379 EQLETLRSKVAQLELQIASLNNEIERLEARLE----RLEDRRERLQQEIEELLKKLEEAELKELQAELE--ELEEELEEL 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1262 TLKLERQELKAKDSDNRLRDSQKRFEEVQSKLANLQ--KSAVESLQNPMSSNSR------QNRSIYVDIP---------- 1323
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQALDAAERELAQLQarLDSLERLQENLEGFSEgvkallKNQSGLSGILgvlselisvd 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1324 ---RAASSIGLNENSDEVPLRSSPSVRFADSS--QNMQRAVDSMDVSSSVGVTLRFLKERIEQLEADNADLSDALEKAKD 1398
Cdd:TIGR02168  533 egyEAAIEAALGGRLQAVVVENLNAAKKAIAFlkQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDP 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1399 ELRQRNEKLADRQMVIERVER--QLVHITEERNTIenrmtSQRQMYLTNEESSRSREHEirsmKARISTLElhlreKESK 1476
Cdd:TIGR02168  613 KLRKALSYLLGGVLVVDDLDNalELAKKLRPGYRI-----VTLDGDLVRPGGVITGGSA----KTNSSILE-----RRRE 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1477 LAHLRKEIEVLHGQLHDALESKEKAtglvgvqDSKHRDLEEQLDRANRERELAIGKQRRTLAENENLFRKLEQLEKEREQ 1556
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAEL-------RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1557 LMREITDERRLNERNRTSLEELRVSERTWKSAMTTAKKPAEEQERAVQEQRRweesnhemtnRNTALTKECDRLRVEMRD 1636
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE----------ALDELRAELTLLNEEAAN 821

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1637 QLNRMNGINLRSVDFERKNEELSSKLIVMQNTVTAMKKFEEEWKRLEAEMRAELKILRKEKLMQTAEIEDLKRKSFRSDT 1716
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSE 901

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1717 EKKEIEGIRVRLEREISALKRHVDALEEEKGKTE---KAVRETMNER-----RAIDKSLASMERENQQLYRNCAQLQAQI 1788
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLELRLEGLEvriDNLQERLSEEysltlEEAEALENKIEDDEEEARRRLKRLENKI 981


                   ...
gi 133903949  1789 QNL 1791
Cdd:TIGR02168  982 KEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 542-1153 1.83e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.68  E-value: 1.83e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  542 ELRETQRSLKGDVAAMKtdLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQ 621
Cdd:COG1196   217 ELKEELKELEAELLLLK--LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  622 AIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEI 701
Cdd:COG1196   295 AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  702 DILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVatwqekyEQLKMELEEMNRRGQEKEREEADLRALLDDL 781
Cdd:COG1196   375 AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERL-------ERLEEELEELEEALAELEEEEEEEEEALEEA 447

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  782 RGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEKDRQGVEnfgk 861
Cdd:COG1196   448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA---- 523

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  862 ECEARMNELTKIHEMLMEEHDQLKVDHLHTEEEverlkEKMRKELEKLNEQNDGdRAEWSNERNRLESSKNEAVTELQER 941
Cdd:COG1196   524 GAVAVLIGVEAAYEAALEAALAAALQNIVVEDD-----EVAAAAIEYLKAAKAG-RATFLPLDKIRARAALAAALARGAI 597

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  942 VQKLEDVVKEKEDKEIALRRDLEDSHEKSRDLDDKLRKMEL--TDEEKEEDRKKEQKTLNEERMKLMEQKEEAMLVATKH 1019
Cdd:COG1196   598 GAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRavTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEA 677

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1020 ATTIDQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEK 1099
Cdd:COG1196   678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP 757

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 133903949 1100 WNEERKKIQDLADQLREANKvvhnmRMKNVNL---------EEKKNELDQNVTDLTNKVRQLE 1153
Cdd:COG1196   758 EPPDLEELERELERLEREIE-----ALGPVNLlaieeyeelEERYDFLSEQREDLEEARETLE 815
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
294-797 6.76e-14

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 77.39  E-value: 6.76e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  294 QKNLDQKEQMKREKDDVLD---ETLRQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQL------- 363
Cdd:PRK02224  226 EEQREQARETRDEADEVLEeheERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLlaeagld 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  364 ----SKMAHEMAGGRGRNETPMDVARKMRKLLTTKNGEIDESREAAKQAEKERDrakkdlEKEEKRRKDDREAERKRSSV 439
Cdd:PRK02224  306 dadaEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAE------ELREEAAELESELEEAREAV 379

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  440 ySQREHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQFIEEL-----MIRHREELKEREDSHEEA 514
Cdd:PRK02224  380 -EDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLrtareRVEEAEALLEAGKCPECG 458

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  515 LRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAMKtDLDDKTLRLDMLETERDELKKKLETEREQADQRDL 594
Cdd:PRK02224  459 QPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAE-DLVEAEDRIERLEERREDLEELIAERRETIEEKRE 537

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  595 EIAECRAKLDEMAEKEAELRKELAEF-QAIITAMEGEGKLNQEQF-----LESKNELNTLTDQIESLNSEVENKNEEIRN 668
Cdd:PRK02224  538 RAEELRERAAELEAEAEEKREAAAEAeEEAEEAREEVAELNSKLAelkerIESLERIRTLLAAIADAEDEIERLREKREA 617

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  669 LMATLQEKEVHIQNVRTSSHQLTATYEEANgeIDILKAELTRLHEqvnertrQISEANEKYDDAARKNDALLEDVATWQE 748
Cdd:PRK02224  618 LAELNDERRERLAEKRERKRELEAEFDEAR--IEEAREDKERAEE-------YLEQVEEKLDELREERDDLQAEIGAVEN 688

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 133903949  749 KYEQLKMELEEMNRRGQEKEREEAdLRALLDDLRGNFDKLTNELKQKGV 797
Cdd:PRK02224  689 ELEELEELRERREALENRVEALEA-LYDEAEELESMYGDLRAELRQRNV 736
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 350-932 4.85e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 74.77  E-value: 4.85e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   350 REQNDELSDILEQLSKMAHEMAGGRGRNETPMDVAR----KMRKLLTTKNGEIDESREAAKQAEKERDRakkdlekeeKR 425
Cdd:pfam15921  134 RRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNtqieQLRKMMLSHEGVLQEIRSILVDFEEASGK---------KI 204

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   426 RKDDREAERKRSSVYSQREHDLKKLDDELRKASEKIRNLEEQRESqekLTISVQNSLNEAHRQHKQFIEELMIRHREE-- 503
Cdd:pfam15921  205 YEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEA---LKSESQNKIELLLQQHQDRIEQLISEHEVEit 281

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   504 -LKEREDSHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDM-----------L 571
Cdd:pfam15921  282 gLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKqlvlanselteA 361

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   572 ETERDEL---------------------KKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEGE 630
Cdd:pfam15921  362 RTERDQFsqesgnlddqlqklladlhkrEKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSE 441

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   631 GKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTR 710
Cdd:pfam15921  442 CQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITK 521

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   711 LHEQVNERTRQiseanekyddaarkndalLEDVATWQEKYEQLKMELEEMNRRGQEKEReeadlraLLDDLRGNFDKLTN 790
Cdd:pfam15921  522 LRSRVDLKLQE------------------LQHLKNEGDHLRNVQTECEALKLQMAEKDK-------VIEILRQQIENMTQ 576

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   791 ELKQKGVTVDSLNEEisslKEQLNKSEKERKEELLRMEELEQKNEAEMKeEYEVKLQLAEKDRQGVENFGKECEARMNEL 870
Cdd:pfam15921  577 LVGQHGRTAGAMQVE----KAQLEKEINDRRLELQEFKILKDKKDAKIR-ELEARVSDLELEKVKLVNAGSERLRAVKDI 651

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 133903949   871 TKIHEMLMEEHDQLKVDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRLESSKN 932
Cdd:pfam15921  652 KQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRN 713
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1375-1862 1.18e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.43  E-value: 1.18e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1375 LKERIEQLEADNADLSDALEKAKDELRQRNEKLADRQMVIERVERQLVHITEERNTIENRMTSQRQMYLTNEESSRSREH 1454
Cdd:COG1196   244 LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEE 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1455 EIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDALESKEKATGLVGVQDSKHRDLEEQLDRANRERELAIGKQR 1534
Cdd:COG1196   324 ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1535 RTLAENENLFRKLEQLEKEREQLMREITDERRLNERNRTSLEELRVSERTWKSAMTTAKKPAEEQERAVQEQRRweesnh 1614
Cdd:COG1196   404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA------ 477

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1615 emtnRNTALTKECDRLRVEMRDQLNRMNGINLRSVDFERKNEELSSKLIVMQNTVTAMKKFEEEWKRLEAEMRAELKILR 1694
Cdd:COG1196   478 ----ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVV 553

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1695 KEKLMQTAEIEDLKRKS------FRSDTEKKEIEGIRVRLEREISALKRHVDALEEEKGKTEKAVRETMNERRAIDKSLA 1768
Cdd:COG1196   554 EDDEVAAAAIEYLKAAKagratfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLE 633

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1769 S---MERENQQLYRNCAQLQAQIQNLERDAGNRSVTKLAKEHSLLEARIAALIEEKRQLQSMLDQKDANYSHKRKLLESQ 1845
Cdd:COG1196   634 AalrRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                         490
                  ....*....|....*..
gi 133903949 1846 IQLLREQLEAERRKRTK 1862
Cdd:COG1196   714 EERLEEELEEEALEEQL 730
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 287-821 1.95e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.58  E-value: 1.95e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  287 KAIRHAEQKNLDQKEQMKREKDDVLDETLRQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQLSKM 366
Cdd:COG1196   245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEE 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  367 AHEMAggrgrnetpmDVARKMRKLLTTKNGEIDESREAAKQAEKERDRAKKDLEKEEKRRKDDREAERKRSSVYSQREHD 446
Cdd:COG1196   325 LAELE----------EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  447 LKKLDDELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQFIEELmiRHREELKEREDSHEEALRSKDTEERSRF 526
Cdd:COG1196   395 AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEAL--EEAAEEEAELEEEEEALLELLAELLEEA 472

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  527 EKERSEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAE---CRAKL 603
Cdd:COG1196   473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALaaaLQNIV 552

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  604 DEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQE-------K 676
Cdd:COG1196   553 VEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGrtlvaarL 632

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  677 EVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVATWQEKYEQLKME 756
Cdd:COG1196   633 EAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEA 712

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 133903949  757 LEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERK 821
Cdd:COG1196   713 EEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIE 777
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 326-619 2.39e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 55.90  E-value: 2.39e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   326 MKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQLSKMAHEMAGGRGRNETPMDVARKMRKLLTTKNGEIDESREAA 405
Cdd:pfam17380  278 VQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEE 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   406 KQAEKERDRAKKDLEKEEKRRKDDR-EAERKRSSVYSQREHDLKKLDDELRKasEKIRNLEEQRESQEKLTISVQNSLNE 484
Cdd:pfam17380  358 RKRELERIRQEEIAMEISRMRELERlQMERQQKNERVRQELEAARKVKILEE--ERQRKIQQQKVEMEQIRAEQEEARQR 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   485 AHRQHKQFIEELMIRHREELKEREDSHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAM-KTDLDD 563
Cdd:pfam17380  436 EVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMiEEERKR 515

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 133903949   564 KTLRLDMLE-------------TERDELKKKLETEREQADQRDLEIAECRAKLDEMaEKEAELRKELAE 619
Cdd:pfam17380  516 KLLEKEMEErqkaiyeeerrreAEEERRKQQEMEERRRIQEQMRKATEERSRLEAM-EREREMMRQIVE 583
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 880-1734 3.53e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.75  E-value: 3.53e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   880 EHDQLKVDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRLESSKNEAVTELQERVQKLEDVVKEKEDKEIAL 959
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   960 RRDLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEEAMLVATKHATTIDQQTRRISVLEGDVEK 1039
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1040 LTAGIAERESSINALESntmELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERKKIQDLADQLREANK 1119
Cdd:pfam02463  326 AEKELKKEKEEIEELEK---ELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSE 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1120 VVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNEQFRLTDLEKVRK 1199
Cdd:pfam02463  403 EEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1200 ALQDENQRLVNDLATVKAAFEVKRETSKSAISDILD-----------KYRSAEEKANKGELDNQRLRSDLATVTLKLERQ 1268
Cdd:pfam02463  483 QEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDgvggriisahgRLGDLGVAVENYKVAISTAVIVEVSATADEVEE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1269 ELKAKDSDNRLRDSQKRFEEVQSKLANLQKSAVESLQNPMSSNSRQNRSI--YVDIPRAASSIGLNENSDEVPLRSSPSV 1346
Cdd:pfam02463  563 RQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATleADEDDKRAKVVEGILKDTELTKLKESAK 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1347 RFADSSQNMQRAVDSMDVSSSVGVTLRFLKERIEQLEADNADLSDALEKAKDELRQRNEKLAD--RQMVIERVERQLVHI 1424
Cdd:pfam02463  643 AKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEqrEKEELKKLKLEAEEL 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1425 TEERNTIENRMTSQRQMYLTNEESSRSREHEIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDALESKEKATGL 1504
Cdd:pfam02463  723 LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1505 VGVQDSKHRDLEEQLDRANRERELAIGKQRRTLAENENLFRKLEQLEKEREQLMREITDERRLNERNRTSLEELRVSERT 1584
Cdd:pfam02463  803 LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQ 882

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1585 WKSAMTTAKKPAEEQERAVQEQR---------RWEESNHEMTNRNTALTKECDRLRVEMRDQLNRMNGINLRSVDFERKN 1655
Cdd:pfam02463  883 KLKDELESKEEKEKEEKKELEEEsqklnlleeKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERN 962

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1656 EELSSKLIVMQNTVTAMKKFEEEWKRLEAEMRAELKIL---RKEKLMQTAEIEDLKRKSFRSDTEKKEIEGIRVRLEREI 1732
Cdd:pfam02463  963 KRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLeeeKKKLIRAIIEETCQRLKEFLELFVSINKGWNKVFFYLEL 1042


                   ..
gi 133903949  1733 SA 1734
Cdd:pfam02463 1043 GG 1044
PTZ00121 PTZ00121
MAEBL; Provisional
 1116-1775 2.85e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.37  E-value: 2.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1116 EANKVVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQ--NEQFRLTD 1193
Cdd:PTZ00121 1059 KAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARkaEEARKAED 1138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1194 LEKVRKALQDENQRLVNDLATVKAAFEVKrETSKSAISDILDKYRSAEE--KANKGELDNQRLRSDLATVTLKLERQELK 1271
Cdd:PTZ00121 1139 ARKAEEARKAEDAKRVEIARKAEDARKAE-EARKAEDAKKAEAARKAEEvrKAEELRKAEDARKAEAARKAEEERKAEEA 1217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1272 AKDSDNRLRDSQKRFEEVQSKlANLQKSAVESLQNPMSSNSRQNRSIYVDIPRAASSIGLNENSDEVplRSSPSVRFADS 1351
Cdd:PTZ00121 1218 RKAEDAKKAEAVKKAEEAKKD-AEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADEL--KKAEEKKKADE 1294

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1352 SQNMQ--RAVDSMDVSSSVGVTLRFLKERIEQLE--ADNADLSDALEKAKDELRQRNEKLADRQM--VIERVERQLVHIT 1425
Cdd:PTZ00121 1295 AKKAEekKKADEAKKKAEEAKKADEAKKKAEEAKkkADAAKKKAEEAKKAAEAAKAEAEAAADEAeaAEEKAEAAEKKKE 1374

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1426 EERNTIENRMTSQRQMYLTNEESSRSREHEIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDA---------LE 1496
Cdd:PTZ00121 1375 EAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAkkadeakkkAE 1454

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1497 SKEKATGLVGVQDSKHRDLEEQLDRANRERELAIGKQRRTLAENENLFRKLEQLEKEREQLMR----EITDERRLNERNR 1572
Cdd:PTZ00121 1455 EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKaeeaKKADEAKKAEEAK 1534

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1573 TSLEELRVSERTWKSAMTTAKKPAEEQERAVQEQRRWEESNHEMTNRNTALTKECDRLRVE----MRDQLNRMNGINLRS 1648
Cdd:PTZ00121 1535 KADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEevmkLYEEEKKMKAEEAKK 1614

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1649 VDFERKNEELSSKLIVMQNTVTAMKKFEEEWKRLEAEMRA--ELKILRKEKLMQTAE-----------IEDLKRKS---- 1711
Cdd:PTZ00121 1615 AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKaeEENKIKAAEEAKKAEedkkkaeeakkAEEDEKKAaeal 1694

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 133903949 1712 FRSDTEKKEIEGIRVRLEREISALKRHVDALEEEKGKTEKAVRETMNERRAIDKSLASMERENQ 1775
Cdd:PTZ00121 1695 KKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKK 1758
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 300-619 3.69e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.73  E-value: 3.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   300 KEQMKREKDDVLDETlRQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDElsdileQLSKMAHEMAGGRGRnET 379
Cdd:TIGR00618  562 KEQMQEIQQSFSILT-QCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHA------LLRKLQPEQDLQDVR-LH 633

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   380 PMDVARKMRKLLTTKNGEideSREAAKQAEKERDRAKKDLEKE--EKRRKDDREAERKRSSVYSQREhDLKKLDDELRKA 457
Cdd:TIGR00618  634 LQQCSQELALKLTALHAL---QLTLTQERVREHALSIRVLPKEllASRQLALQKMQSEKEQLTYWKE-MLAQCQTLLREL 709

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   458 SEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQFIEELMIRHREELKEREDSHEEALRSKDTEERSRFEKERSEREkIR 537
Cdd:TIGR00618  710 ETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAE-IQ 788

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   538 RESDELRETQRSLKGDVAAMKT----DLDDKTLRLDMLETERDELKKKLE---TEREQADQRDLEIAECRAKLDEMAEKE 610
Cdd:TIGR00618  789 FFNRLREEDTHLLKTLEAEIGQeipsDEDILNLQCETLVQEEEQFLSRLEeksATLGEITHQLLKYEECSKQLAQLTQEQ 868


                   ....*....
gi 133903949   611 AELRKELAE 619
Cdd:TIGR00618  869 AKIIQLSDK 877
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 568-1297 6.50e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 107.06  E-value: 6.50e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   568 LDMLETERDELKKKLETEREQADQrdleiaecrakldemAEKEAELRKELAEFQAIITAMEgegklnqeqFLESKNELNT 647
Cdd:TIGR02168  188 LDRLEDILNELERQLKSLERQAEK---------------AERYKELKAELRELELALLVLR---------LEELREELEE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   648 LTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANE 727
Cdd:TIGR02168  244 LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   728 KYDDAARKNDALLEDVATWQEKYEQLKME-------LEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKqkgvtvd 800
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEEKLEELKEElesleaeLEELEAELEELESRLEELEEQLETLRSKVAQLELQIA------- 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   801 SLNEEISSLKEQLNKSEKERkeellrmeeleqKNEAEMKEEYEVKLQLAEKDRqgvenfgkecearmneltkiHEMLMEE 880
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRR------------ERLQQEIEELLKKLEEAELKE--------------------LQAELEE 444

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   881 HDQLKVDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRLESSKNeavteLQERVQKLEDVVKEKEDK----- 955
Cdd:TIGR02168  445 LEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER-----LQENLEGFSEGVKALLKNqsgls 519

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   956 --------------------EIALRRDLE----DSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEE 1011
Cdd:TIGR02168  520 gilgvlselisvdegyeaaiEAALGGRLQavvvENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEG 599

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1012 AMLVATKH--------------------ATTIDQQTR---------RISVLEGDV-----------EKLTAGIAERESSI 1051
Cdd:TIGR02168  600 FLGVAKDLvkfdpklrkalsyllggvlvVDDLDNALElakklrpgyRIVTLDGDLvrpggvitggsAKTNSSILERRREI 679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1052 NALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERK-------KIQDLADQLREANKVVHNM 1124
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKdlarleaEVEQLEERIAQLSKELTEL 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1125 RMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNEQFRLTDLEKVRKALQDE 1204
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERR 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1205 NQRLVNDLATVK---AAFEVKRETSKSAISDILDKYRSAEEKANKGELDNQRLRSDLATVTLKLERQELKAKDSDNRLRD 1281
Cdd:TIGR02168  840 LEDLEEQIEELSediESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE 919

                          810
                   ....*....|....*.
gi 133903949  1282 SQKRFEEVQSKLANLQ 1297
Cdd:TIGR02168  920 LREKLAQLELRLEGLE 935
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
162-282 7.29e-23

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 97.80  E-value: 7.29e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   162 EENLDELFAKLKEELFKNNTLEEVNEMLREENDAALAANEHLRVDATNLSRQLQQLQQQQHTESMRFRSENTRYRNQTET 241
Cdd:pfam15035   70 SADLEEALIRLEEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSS 149

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 133903949   242 QHRKLISLWKEFTAVKRQLHELRTTTANDLDRQLTEFTRCA 282
Cdd:pfam15035  150 EHSRLLSLWREVVAVRRQFTELKTATERDLSELKTEFSRTS 190
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 424-1267 4.01e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 104.75  E-value: 4.01e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   424 KRRKDDREAERKRSSVysqrEHDLKKLDDELRKASEKIRNLEEQRESQEKLtISVQNSLNEAHRqhkqfieELMIRHREE 503
Cdd:TIGR02168  169 KYKERRKETERKLERT----RENLDRLEDILNELERQLKSLERQAEKAERY-KELKAELRELEL-------ALLVLRLEE 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   504 LKEredsHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLE 583
Cdd:TIGR02168  237 LRE----ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   584 TEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKN 663
Cdd:TIGR02168  313 NLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   664 EEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDilKAELTRLHEQVNERTRQISEANEKYDDAarkndalledv 743
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLE--EAELKELQAELEELEEELEELQEELERL----------- 459

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   744 atwQEKYEQLKMELEEMNRRGQEKEREEADLRALLD---DLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKER 820
Cdd:TIGR02168  460 ---EEALEELREELEEAEQALDAAERELAQLQARLDsleRLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYE 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   821 KEELLRMEELEQKNEAEMKEEYEVKLQLAEKDRQGVENFGKECEARMNELTKIHEMLMEEHD---QLKVDHLHTEEE--- 894
Cdd:TIGR02168  537 AAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEgflGVAKDLVKFDPKlrk 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   895 -----------VERLKEKMRKELEKLNEQN----DGDRAEWSNERNRLESSKNEAVTELQERVQKLEDVVKEKEDKEIAL 959
Cdd:TIGR02168  617 alsyllggvlvVDDLDNALELAKKLRPGYRivtlDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAEL 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   960 RRDLEDSHEKSRDLDDKLRKmeltdeekeedrkkEQKTLNEERMKLMEQKEEamlvATKHATTIDQQTRRISVLEGDVEK 1039
Cdd:TIGR02168  697 EKALAELRKELEELEEELEQ--------------LRKELEELSRQISALRKD----LARLEAEVEQLEERIAQLSKELTE 758

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1040 LTAGIAERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERKKIQDLADQLREANK 1119
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATER 838

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1120 vvhnmrmKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNEQFRLTDLEKVRK 1199
Cdd:TIGR02168  839 -------RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRS 911

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 133903949  1200 ALQDENQRL---VNDLATVKAAFEVKRETSKSAISDIL-DKYRSAEEKANKGELDNQRLRSDLATVTLKLER 1267
Cdd:TIGR02168  912 ELRRELEELrekLAQLELRLEGLEVRIDNLQERLSEEYsLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 313-1163 9.34e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.58  E-value: 9.34e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   313 ETLRQLNSVTENYMKSEEKANERQRDLKRKEDECRK---LREQNDELSDILEQLSKMahemaggrgrnetpmdvarkmrk 389
Cdd:TIGR02168  176 ETERKLERTRENLDRLEDILNELERQLKSLERQAEKaerYKELKAELRELELALLVL----------------------- 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   390 LLTTKNGEIDESREAAKQAEKERDRAKKDLEKEE--------KRRKDDREAERKRSSVYSQREhDLKKLDDELRKASEKI 461
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEekleelrlEVSELEEEIEELQKELYALAN-EISRLEQQKQILRERL 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   462 RNLEEQRESqekltISVQNSLNEAHRQHKQFIEELMIRHREELKEREDSHEEAL---RSKDTEERSRFEKERSEREKIRR 538
Cdd:TIGR02168  312 ANLERQLEE-----LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELeelEAELEELESRLEELEEQLETLRS 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   539 ESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLEtereqadqrDLEIAECRAKLDEMAEKEAELRKELA 618
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLE---------EAELKELQAELEELEEELEELQEELE 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   619 EFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEV-------------------- 678
Cdd:TIGR02168  458 RLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGlsgilgvlselisvdegyea 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   679 --------HIQNVrtsshqLTATYEEANGEIDILK---------AELTRLHEQVNERTRQISEAN-----------EKYD 730
Cdd:TIGR02168  538 aieaalggRLQAV------VVENLNAAKKAIAFLKqnelgrvtfLPLDSIKGTEIQGNDREILKNiegflgvakdlVKFD 611

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   731 DAARKNDALL-------EDVATWQEKYEQLKMEL-------EEMNRRG-------------QEKEREEADLRALLDDLRG 783
Cdd:TIGR02168  612 PKLRKALSYLlggvlvvDDLDNALELAKKLRPGYrivtldgDLVRPGGvitggsaktnssiLERRREIEELEEKIEELEE 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   784 NFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKErkeellrmeeleqknEAEMKEEYEVKLQLAEKDRQGVENFGKEC 863
Cdd:TIGR02168  692 KIAELEKALAELRKELEELEEELEQLRKELEELSRQ---------------ISALRKDLARLEAEVEQLEERIAQLSKEL 756

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   864 EARMNELTKIHEMLMEEHDQLKVDhlhteeeverlkekmRKELEKLNEQNDGDRAEWSNERNRLeSSKNEAVTELQERVQ 943
Cdd:TIGR02168  757 TELEAEIEELEERLEEAEEELAEA---------------EAEIEELEAQIEQLKEELKALREAL-DELRAELTLLNEEAA 820

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   944 KLEDVVKEKEDKEIALRRDLEDSHEKSRDLDDKLRKmeltdeekeedrkkeqktLNEERMKLMEQKEEAMLVATKHATTI 1023
Cdd:TIGR02168  821 NLRERLESLERRIAATERRLEDLEEQIEELSEDIES------------------LAAEIEELEELIEELESELEALLNER 882

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1024 DQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQ-NSELKNGKEGLSEKWNE 1102
Cdd:TIGR02168  883 ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlSEEYSLTLEEAEALENK 962

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 133903949  1103 ERKKIQDLADQLREANKVVHnmRMKNVNL---------EEKKNELDQNVTDLTNKVRQLE--IQLMDKAAKN 1163
Cdd:TIGR02168  963 IEDDEEEARRRLKRLENKIK--ELGPVNLaaieeyeelKERYDFLTAQKEDLTEAKETLEeaIEEIDREARE 1032
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 591-952 8.57e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.50  E-value: 8.57e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   591 QRDLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLM 670
Cdd:TIGR02168  674 ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLS 753

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   671 ATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVATWQEKY 750
Cdd:TIGR02168  754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI 833

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   751 EQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEEL 830
Cdd:TIGR02168  834 AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSEL 913

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   831 EQKNEAEMKEEYEVKLQLaekdrQGVENFGKECEARMNELtkiHEMLMEEHDQLKVDHLHTEEEVERLKEKMRKELEKLN 910
Cdd:TIGR02168  914 RRELEELREKLAQLELRL-----EGLEVRIDNLQERLSEE---YSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELG 985

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*...
gi 133903949   911 EQNDGDRAEWSNERNRLE------SSKNEAVTELQERVQKLEDVVKEK 952
Cdd:TIGR02168  986 PVNLAAIEEYEELKERYDfltaqkEDLTEAKETLEEAIEEIDREARER 1033
PTZ00121 PTZ00121
MAEBL; Provisional
 384-1141 2.23e-17

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 89.43  E-value: 2.23e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  384 ARKMRKLLTTKNGEIDESREAAKQAEKERD-----RAKKDLEKEEKRRKDD-------REAERKRSSVYSQREHDLKKLD 451
Cdd:PTZ00121 1100 AEEAKKTETGKAEEARKAEEAKKKAEDARKaeearKAEDARKAEEARKAEDakrveiaRKAEDARKAEEARKAEDAKKAE 1179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  452 D-----ELRKASEkIRNLEEQRESQEKLTISVQNSLNEAHR-QHKQFIEElmIRHREELKEREDSHEEALRSKDTEERSR 525
Cdd:PTZ00121 1180 AarkaeEVRKAEE-LRKAEDARKAEAARKAEEERKAEEARKaEDAKKAEA--VKKAEEAKKDAEEAKKAEEERNNEEIRK 1256

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  526 FEKERSEREKIR---------RESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETER--DELKKKLETEREQADQRDL 594
Cdd:PTZ00121 1257 FEEARMAHFARRqaaikaeeaRKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKkaDEAKKKAEEAKKKADAAKK 1336

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  595 EiAECRAKLDEMAEKEAELRK---ELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMA 671
Cdd:PTZ00121 1337 K-AEEAKKAAEAAKAEAEAAAdeaEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAA 1415

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  672 T---LQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANE--KYDDAARKNDALLEDVATW 746
Cdd:PTZ00121 1416 AkkkADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEakKKAEEAKKADEAKKKAEEA 1495

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  747 QEKYEQLKMELEEMNRRGQEKEREEAdlrALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSlkEQLNKSEKERKEELLR 826
Cdd:PTZ00121 1496 KKKADEAKKAAEAKKKADEAKKAEEA---KKADEAKKAEEAKKADEAKKAEEKKKADELKKA--EELKKAEEKKKAEEAK 1570

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  827 MEELEQKNEAEMKEEyevkLQLAEKDRQGVENFGKECEARMneltKIHEMLMEEHDQLKVDHLHTEEEVERLKEKMRKEL 906
Cdd:PTZ00121 1571 KAEEDKNMALRKAEE----AKKAEEARIEEVMKLYEEEKKM----KAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKE 1642

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  907 EKLNEQNDGDRAEWSNERNRLESSKNEAvtelQERVQKLEDVVKEKEDKEIALRRDLEDSHEKSRdlDDKLRKMElTDEE 986
Cdd:PTZ00121 1643 AEEKKKAEELKKAEEENKIKAAEEAKKA----EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK--AEELKKKE-AEEK 1715

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  987 KEEDRKKEQKTLNEERMKLMEQKEEAMLVATKHATTIDQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELISKLE 1066
Cdd:PTZ00121 1716 KKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRME 1795

                         730       740       750       760       770       780       790
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 133903949 1067 tTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERKKIQDLADQLREANKVV--HNMRMKNVNLEEKKNELDQN 1141
Cdd:PTZ00121 1796 -VDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFekHKFNKNNENGEDGNKEADFN 1871
PTZ00121 PTZ00121
MAEBL; Provisional
 328-1159 4.23e-17

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 88.27  E-value: 4.23e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  328 SEEKANERQRDLKRKEDECRKLREQNDELSDILEQLSKMAHEMAGGRGRNETPMDVARKMRKLLTTKNGEIDESREAAKQ 407
Cdd:PTZ00121 1068 QDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARK 1147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  408 AEKERDRAKKDLEKEEKRRKDDREAERKRSSVYSQREHDLKKLDdELRKAsEKIRNLEEQRESQEKLTISVQNSLNEAHR 487
Cdd:PTZ00121 1148 AEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAE-ELRKA-EDARKAEAARKAEEERKAEEARKAEDAKK 1225

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  488 qhkqfIEElmIRHREELKEREDSHEEALRSKDTEERSRFEKERSEREKIR---------RESDELRETQRSLKGDVAAMK 558
Cdd:PTZ00121 1226 -----AEA--VKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRqaaikaeeaRKADELKKAEEKKKADEAKKA 1298

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  559 TDLDDKTLRLDMLETER--DELKKKLETEREQADQRDLEiAECRAKLDEMAEKEAELRK---ELAEFQAIITAMEGEGKL 633
Cdd:PTZ00121 1299 EEKKKADEAKKKAEEAKkaDEAKKKAEEAKKKADAAKKK-AEEAKKAAEAAKAEAEAAAdeaEAAEEKAEAAEKKKEEAK 1377

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  634 NQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMAT---LQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTR 710
Cdd:PTZ00121 1378 KKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAkkkADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAK 1457

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  711 LHEQVNERTRQISEANE--KYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEAdlrALLDDLRGNFDKL 788
Cdd:PTZ00121 1458 KAEEAKKKAEEAKKADEakKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEA---KKADEAKKAEEAK 1534

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  789 TNELKQKGVTVDSLNE----EISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEE---YEVKLQLAEKDRQGVENFGK 861
Cdd:PTZ00121 1535 KADEAKKAEEKKKADElkkaEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEariEEVMKLYEEEKKMKAEEAKK 1614

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  862 ECEARMneltKIHEMLMEEHDQLKVDHLHTEEEVERLK----------EKMRKELEKLNEQNDGDRAEWSNERNRLESSK 931
Cdd:PTZ00121 1615 AEEAKI----KAEELKKAEEEKKKVEQLKKKEAEEKKKaeelkkaeeeNKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKA 1690

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  932 NEAVTELQERVQKLEDVVKEKED---KEIALRRDLEDSHEKSRDL-----DDKLRKMELTDEEKEEDRKKEQKTLNEERM 1003
Cdd:PTZ00121 1691 AEALKKEAEEAKKAEELKKKEAEekkKAEELKKAEEENKIKAEEAkkeaeEDKKKAEEAKKDEEEKKKIAHLKKEEEKKA 1770

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1004 KLMEQKEEAML---VATKHATTIDQQTRRISVLEGDVEKLTAGIAERESSINAL-ESNTMELISKLETTEAELEKLKDEL 1079
Cdd:PTZ00121 1771 EEIRKEKEAVIeeeLDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSkEMEDSAIKEVADSKNMQLEEADAFE 1850

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1080 AVMLKQNSElkNGKEGLSE-KWNEERKKIQDLADQLREANKVVH-------------NMRMKNVNLEEKKNELDQNVTDL 1145
Cdd:PTZ00121 1851 KHKFNKNNE--NGEDGNKEaDFNKEKDLKEDDEEEIEEADEIEKidkddiereipnnNMAGKNNDIIDDKLDKDEYIKRD 1928

                         890
                  ....*....|....
gi 133903949 1146 TNKVRQLEIQLMDK 1159
Cdd:PTZ00121 1929 AEETREEIIKISKK 1942
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
447-956 6.12e-17

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 87.40  E-value: 6.12e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  447 LKKLDDELRKASEKIRNLEEQREsQEKLTISVQNSLNEAHRQHKQFIEEL--MIRHREELKEREDSHEEALRSKDTEERS 524
Cdd:PRK02224  208 LNGLESELAELDEEIERYEEQRE-QARETRDEADEVLEEHEERREELETLeaEIEDLRETIAETEREREELAEEVRDLRE 286

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  525 RFEKERSEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAECRAKLD 604
Cdd:PRK02224  287 RLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAA 366

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  605 EMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHI---- 680
Cdd:PRK02224  367 ELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVeeae 446

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  681 ------------QNVRTSSHqlTATYEEANGEIDILKAELTRLHEQVNERTRQISEAnEKYDDAARKNDALLEDVATWQE 748
Cdd:PRK02224  447 alleagkcpecgQPVEGSPH--VETIEEDRERVEELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDLEE 523

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  749 KYEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLnksekERKEELLRME 828
Cdd:PRK02224  524 LIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERI-----ESLERIRTLL 598

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  829 ELEQKNEAEMKEEYEVKLQLAEKDRQGVEnfgkeceaRMNELTKIHEMLMEEHDQLKVDHLHTE-EEVERLKEKMRKELE 907
Cdd:PRK02224  599 AAIADAEDEIERLREKREALAELNDERRE--------RLAEKRERKRELEAEFDEARIEEAREDkERAEEYLEQVEEKLD 670

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|.
gi 133903949  908 KLNEQNDGDRAEWSNERNRLESSKN--EAVTELQERVQKLEDVVKEKEDKE 956
Cdd:PRK02224  671 ELREERDDLQAEIGAVENELEELEElrERREALENRVEALEALYDEAEELE 721
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 879-1737 2.75e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.49  E-value: 2.75e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   879 EEHDQLKVDHLHTEEEVERLKEKMRKELEKLNEQNDgdraewsnERNRLESSKNEAVTELQERVQKLEDVVKEKEDKEIA 958
Cdd:TIGR02168  239 EELEELQEELKEAEEELEELTAELQELEEKLEELRL--------EVSELEEEIEELQKELYALANEISRLEQQKQILRER 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   959 LRRDLEDSHEKSRDLDDKLRKMEltdeekeedrkkeqktlneermklmEQKEEAmlvatkhattiDQQTRRISVLEGDVE 1038
Cdd:TIGR02168  311 LANLERQLEELEAQLEELESKLD-------------------------ELAEEL-----------AELEEKLEELKEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1039 KLTAGIAERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERKKIQDLADQLREAN 1118
Cdd:TIGR02168  355 SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1119 KVVHNMRmknvnLEEKKNELDQNVTDLTNKVRQLEIqLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNEQFRLTDLEKVR 1198
Cdd:TIGR02168  435 LKELQAE-----LEELEEELEELQEELERLEEALEE-LREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGV 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1199 KALQDENQRLVNDLATVKAAFEVKRETSKS---AISDILDKYRSAEEKANKGELDNQRlRSDLATVTLkLERQELKAKDS 1275
Cdd:TIGR02168  509 KALLKNQSGLSGILGVLSELISVDEGYEAAieaALGGRLQAVVVENLNAAKKAIAFLK-QNELGRVTF-LPLDSIKGTEI 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1276 DNRLRDSQKRFEEVQSKLANLQKSAVEsLQNPMssNSRQNRSIYVDIPRAASSIGLNENSDEVP-------LRSSPSVRF 1348
Cdd:TIGR02168  587 QGNDREILKNIEGFLGVAKDLVKFDPK-LRKAL--SYLLGGVLVVDDLDNALELAKKLRPGYRIvtldgdlVRPGGVITG 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1349 ADSSQNMQRAvdsmdvssSVGVTLRFLKERIEQLEADNADLSDALEKAKDELRQRNEKLADRQMVIERVERQLVHITEER 1428
Cdd:TIGR02168  664 GSAKTNSSIL--------ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDL 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1429 NTIENRMTSQRQMYLTNEESSRSREHEIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLhdaleskekatglvGVQ 1508
Cdd:TIGR02168  736 ARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEEL--------------KAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1509 DSKHRDLEEQLDRANRErelaIGKQRRTLaenENLFRKLEQLEKEREQLMREITDERRLNERNRTSLEELRVSERTWKSA 1588
Cdd:TIGR02168  802 REALDELRAELTLLNEE----AANLRERL---ESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE 874

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1589 MTTAKKPAEEQERAVQEQRR----WEESNHEMTNRNTALTKECDRLRVEMRDQLNRMNGINLRSVDF-ERKNEELSSKLI 1663
Cdd:TIGR02168  875 LEALLNERASLEEALALLRSeleeLSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLqERLSEEYSLTLE 954

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 133903949  1664 VMQNTVTAMKKFEEEWKRLEAEMRAELKILRKEKLMQTAEIEDLK-RKSFRsDTEKKEIEGIRVRLEREISALKR 1737
Cdd:TIGR02168  955 EAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKeRYDFL-TAQKEDLTEAKETLEEAIEEIDR 1028
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 268-1116 5.78e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.34  E-value: 5.78e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   268 ANDLDRQLTEFTRCAtlmRKAIRHAEQKN-LDQKE-----QMKREKDDVLDETLRQLNSVTENYMKSEEKANERQRDLKR 341
Cdd:TIGR02168  195 LNELERQLKSLERQA---EKAERYKELKAeLRELElallvLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   342 KEDECRKLREQNDELSDILEQLSKMAHEMaggrgrnETPMDVARKMRKLLTTKNGEIDESREAAKQAEKERDRAKKDLEK 421
Cdd:TIGR02168  272 LRLEVSELEEEIEELQKELYALANEISRL-------EQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   422 EEKRRKDDREAERKR----SSVYSQREHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQFIEELm 497
Cdd:TIGR02168  345 KLEELKEELESLEAEleelEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEI- 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   498 irhREELKEREDSHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDE 577
Cdd:TIGR02168  424 ---EELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEN 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   578 LKKKLETEREQADQRdLEIAECRAKLDEMAEKEAELRKELAE-----FQAIItaMEGEGKLNQEQFLESKNELNTLT--- 649
Cdd:TIGR02168  501 LEGFSEGVKALLKNQ-SGLSGILGVLSELISVDEGYEAAIEAalggrLQAVV--VENLNAAKKAIAFLKQNELGRVTflp 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   650 ------DQIESLNSEVENKNEEIRNLMATLQEKEVHIQNV---RTSSHQLTATYEEANGEIDILKAE------------- 707
Cdd:TIGR02168  578 ldsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyLLGGVLVVDDLDNALELAKKLRPGyrivtldgdlvrp 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   708 ---LTRLHEQVN----ERTRQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDD 780
Cdd:TIGR02168  658 ggvITGGSAKTNssilERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   781 LRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKeellrmeeleqkneaemkeEYEVKLQLAEKDRQGVENfg 860
Cdd:TIGR02168  738 LEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELA-------------------EAEAEIEELEAQIEQLKE-- 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   861 keceaRMNELTKIHEMLMEEHDQLKVDHLHTEEEVERL------KEKMRKELEKLNEQNDGDRAEWSNERNRLEssknEA 934
Cdd:TIGR02168  797 -----ELKALREALDELRAELTLLNEEAANLRERLESLerriaaTERRLEDLEEQIEELSEDIESLAAEIEELE----EL 867

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   935 VTELQERVQKLEDVVKEKEDKEIALRRDLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEEaml 1014
Cdd:TIGR02168  868 IEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER--- 944

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1015 VATKHATTIDQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELIskletteAELEKLKDELAVMLKQNSELKNGKE 1094
Cdd:TIGR02168  945 LSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAI-------EEYEELKERYDFLTAQKEDLTEAKE 1017

                          890       900
                   ....*....|....*....|....*.
gi 133903949  1095 GLSE---KWNEE-RKKIQDLADQLRE 1116
Cdd:TIGR02168 1018 TLEEaieEIDREaRERFKDTFDQVNE 1043
PTZ00121 PTZ00121
MAEBL; Provisional
 277-1011 8.19e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 84.04  E-value: 8.19e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  277 EFTRCATLMRKAIRHAEQKNLDQKEQMKREKDDVLDETLRQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDEL 356
Cdd:PTZ00121 1173 EDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNE 1252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  357 SDILEQLSKMAHEMAGGRGRNetpmdvARKMRKLLTTKNGEIDESREAAKQAEKERDRAKKDLEKEEKRRKDDreaERKR 436
Cdd:PTZ00121 1253 EIRKFEEARMAHFARRQAAIK------AEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADE---AKKK 1323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  437 SSVYSQREHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQFIEELMIRHREELKEREDSHEEALR 516
Cdd:PTZ00121 1324 AEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEED 1403

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  517 SKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAMKTDlddkTLRLDMLETERDELKKKLETEREQADQRDLEI 596
Cdd:PTZ00121 1404 KKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKAD----EAKKKAEEAKKAEEAKKKAEEAKKADEAKKKA 1479

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  597 AECRaKLDEMAEKEAELRKELAEFQaiiTAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEK 676
Cdd:PTZ00121 1480 EEAK-KADEAKKKAEEAKKKADEAK---KAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAE 1555

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  677 EVHIQNVRTSSHQltATYEEANGEIDILKAELTRLHEQ--------VNERTRQISEANEKYDDAARKNDALLEDVATWQE 748
Cdd:PTZ00121 1556 ELKKAEEKKKAEE--AKKAEEDKNMALRKAEEAKKAEEarieevmkLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKK 1633

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  749 KYEQLKMELEEMNRRGQEKEREEADLRALLDDLRgnfdKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKeellrME 828
Cdd:PTZ00121 1634 KVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEA----KKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAK-----KA 1704

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  829 ELEQKNEAEMKEEYEVKLQLAEKDRQGVENFGKECEarmNELTKIHEMLMEEHDQLKVDHLHTEEEVERLKEKMRKEL-- 906
Cdd:PTZ00121 1705 EELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAE---EDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAvi 1781

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  907 -EKLNEQNDGDRAEwsNERNRLESSKNEAVteLQERVQKLEDVVKEKEDKEIALRRDLEDSHEKSRDLDDKLRKMELTDE 985
Cdd:PTZ00121 1782 eEELDEEDEKRRME--VDKKIKDIFDNFAN--IIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKN 1857

                         730       740
                  ....*....|....*....|....*.
gi 133903949  986 EKEEDRKKEQKTLNEERMKLMEQKEE 1011
Cdd:PTZ00121 1858 NENGEDGNKEADFNKEKDLKEDDEEE 1883
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 240-969 8.24e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.95  E-value: 8.24e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   240 ETQHRKLISLWKEFTAVKRQLHELrTTTANDLDRQLTEFTRCATLMRKAIRHAEQKNLDQK------EQMKREKDDVLDE 313
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEEL-TAELQELEEKLEELRLEVSELEEEIEELQKELYALAneisrlEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   314 TLRQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQLSKMAHEMAGGrgrnetpmdvARKMRKLLTT 393
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR----------LEELEEQLET 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   394 KNGEIDESREAAKQAEKERDRAKKDLEKEEKRRkdDREAERKRSSVYSQREHDLKKLDDELRKASEKIRNLEEQRESQEK 473
Cdd:TIGR02168  384 LRSKVAQLELQIASLNNEIERLEARLERLEDRR--ERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEE 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   474 LTISVQNSLNEAHRQHKQFIEELmirhrEELKEREDSHEEALRSKDTEERSRFE--KERSEREKIR---------RESDE 542
Cdd:TIGR02168  462 ALEELREELEEAEQALDAAEREL-----AQLQARLDSLERLQENLEGFSEGVKAllKNQSGLSGILgvlselisvDEGYE 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   543 --------------LRETQRSLKGDVAAMKTDLDDKTLRLdMLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAE 608
Cdd:TIGR02168  537 aaieaalggrlqavVVENLNAAKKAIAFLKQNELGRVTFL-PLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLR 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   609 K-----------------EAELRKELAEFQAIIT----------AMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVEN 661
Cdd:TIGR02168  616 KalsyllggvlvvddldnALELAKKLRPGYRIVTldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAE 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   662 KNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAE-------LTRLHEQVNERTRQISEANEKYDDAAR 734
Cdd:TIGR02168  696 LEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEveqleerIAQLSKELTELEAEIEELEERLEEAEE 775

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   735 KNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLN 814
Cdd:TIGR02168  776 ELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIE 855

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   815 KSEKERKEELLRMEELEQKNEA--EMKEEYEVKLQLAEKDRQGVENFGKECEARMNELTKIHEMLMEEHDQLKVDHLHTE 892
Cdd:TIGR02168  856 SLAAEIEELEELIEELESELEAllNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE 935

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   893 EEVERLKEKMRKE-------LEKLNEQNDGDRAEWSNERNRLESSKNE-------AVTELQERVQKLEDVVKEKEDKEIA 958
Cdd:TIGR02168  936 VRIDNLQERLSEEysltleeAEALENKIEDDEEEARRRLKRLENKIKElgpvnlaAIEEYEELKERYDFLTAQKEDLTEA 1015

                          810
                   ....*....|.
gi 133903949   959 lRRDLEDSHEK 969
Cdd:TIGR02168 1016 -KETLEEAIEE 1025
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1029-1791 9.92e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.57  E-value: 9.92e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1029 RISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAELEKLKDELavmlkqnSELKNGKEGLSEKWNEERKKIQ 1108
Cdd:TIGR02168  226 ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV-------SELEEEIEELQKELYALANEIS 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1109 DLADQLREANKVVHNMRMKNV-------NLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSML 1181
Cdd:TIGR02168  299 RLEQQKQILRERLANLERQLEeleaqleELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1182 KQAQNEQFRLTDLEKVRKALQDENQRLVNDLAtvkaAFEVKRETSKSAISDILDKYRSAEEKANKGELDnqRLRSDLATV 1261
Cdd:TIGR02168  379 EQLETLRSKVAQLELQIASLNNEIERLEARLE----RLEDRRERLQQEIEELLKKLEEAELKELQAELE--ELEEELEEL 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1262 TLKLERQELKAKDSDNRLRDSQKRFEEVQSKLANLQ--KSAVESLQNPMSSNSR------QNRSIYVDIP---------- 1323
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQALDAAERELAQLQarLDSLERLQENLEGFSEgvkallKNQSGLSGILgvlselisvd 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1324 ---RAASSIGLNENSDEVPLRSSPSVRFADSS--QNMQRAVDSMDVSSSVGVTLRFLKERIEQLEADNADLSDALEKAKD 1398
Cdd:TIGR02168  533 egyEAAIEAALGGRLQAVVVENLNAAKKAIAFlkQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDP 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1399 ELRQRNEKLADRQMVIERVER--QLVHITEERNTIenrmtSQRQMYLTNEESSRSREHEirsmKARISTLElhlreKESK 1476
Cdd:TIGR02168  613 KLRKALSYLLGGVLVVDDLDNalELAKKLRPGYRI-----VTLDGDLVRPGGVITGGSA----KTNSSILE-----RRRE 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1477 LAHLRKEIEVLHGQLHDALESKEKAtglvgvqDSKHRDLEEQLDRANRERELAIGKQRRTLAENENLFRKLEQLEKEREQ 1556
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAEL-------RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1557 LMREITDERRLNERNRTSLEELRVSERTWKSAMTTAKKPAEEQERAVQEQRRweesnhemtnRNTALTKECDRLRVEMRD 1636
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE----------ALDELRAELTLLNEEAAN 821

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1637 QLNRMNGINLRSVDFERKNEELSSKLIVMQNTVTAMKKFEEEWKRLEAEMRAELKILRKEKLMQTAEIEDLKRKSFRSDT 1716
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSE 901

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1717 EKKEIEGIRVRLEREISALKRHVDALEEEKGKTE---KAVRETMNER-----RAIDKSLASMERENQQLYRNCAQLQAQI 1788
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLELRLEGLEvriDNLQERLSEEysltlEEAEALENKIEDDEEEARRRLKRLENKI 981


                   ...
gi 133903949  1789 QNL 1791
Cdd:TIGR02168  982 KEL 984
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
464-960 1.10e-15

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 83.17  E-value: 1.10e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  464 LEEQRESQEKLTISVQNSLNEAHRQHKQFIEELMIRHREELKEREDSHEEALRSKDtEERSRFEKERSEREKIRRESDEL 543
Cdd:PRK02224  164 LEEYRERASDARLGVERVLSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELD-EEIERYEEQREQARETRDEADEV 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  544 RETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAECRAK--------------LDEMAEK 609
Cdd:PRK02224  243 LEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEaglddadaeavearREELEDR 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  610 EAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQ 689
Cdd:PRK02224  323 DEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGD 402

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  690 LTATYEEANGEIDILKAELTRLHEQVNERTRQISEAnekyDDAARKNDALLEdvatwQEKYEQLKMELEEMNR--RGQEK 767
Cdd:PRK02224  403 APVDLGNAEDFLEELREERDELREREAELEATLRTA----RERVEEAEALLE-----AGKCPECGQPVEGSPHveTIEED 473

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  768 EREEADLRALLDDLRGNFDKLTNELKQkGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEELEQKNEA--EMKEEYEVK 845
Cdd:PRK02224  474 RERVEELEAELEDLEEEVEEVEERLER-AEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEElrERAAELEAE 552

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  846 LQLAEKDRQGVENFGKECEARMNELTKIHEMLMEEHDQLK--VDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNE 923
Cdd:PRK02224  553 AEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLEriRTLLAAIADAEDEIERLREKREALAELNDERRERLAEK 632

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|.
gi 133903949  924 RNR---LESSKNEA-VTELQERVQKLEDVVKEKEDKEIALR 960
Cdd:PRK02224  633 RERkreLEAEFDEArIEEAREDKERAEEYLEQVEEKLDELR 673
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 542-1153 1.83e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.68  E-value: 1.83e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  542 ELRETQRSLKGDVAAMKtdLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQ 621
Cdd:COG1196   217 ELKEELKELEAELLLLK--LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  622 AIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEI 701
Cdd:COG1196   295 AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  702 DILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVatwqekyEQLKMELEEMNRRGQEKEREEADLRALLDDL 781
Cdd:COG1196   375 AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERL-------ERLEEELEELEEALAELEEEEEEEEEALEEA 447

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  782 RGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEKDRQGVEnfgk 861
Cdd:COG1196   448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA---- 523

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  862 ECEARMNELTKIHEMLMEEHDQLKVDHLHTEEEverlkEKMRKELEKLNEQNDGdRAEWSNERNRLESSKNEAVTELQER 941
Cdd:COG1196   524 GAVAVLIGVEAAYEAALEAALAAALQNIVVEDD-----EVAAAAIEYLKAAKAG-RATFLPLDKIRARAALAAALARGAI 597

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  942 VQKLEDVVKEKEDKEIALRRDLEDSHEKSRDLDDKLRKMEL--TDEEKEEDRKKEQKTLNEERMKLMEQKEEAMLVATKH 1019
Cdd:COG1196   598 GAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRavTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEA 677

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1020 ATTIDQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEK 1099
Cdd:COG1196   678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP 757

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 133903949 1100 WNEERKKIQDLADQLREANKvvhnmRMKNVNL---------EEKKNELDQNVTDLTNKVRQLE 1153
Cdd:COG1196   758 EPPDLEELERELERLEREIE-----ALGPVNLlaieeyeelEERYDFLSEQREDLEEARETLE 815
PTZ00121 PTZ00121
MAEBL; Provisional
 394-1163 3.05e-15

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 82.11  E-value: 3.05e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  394 KNGEIDESREAAKQAEKERDRAKKDLEKEEKRRKDDREAERKRSSVYSQREHDLKKLdDELRKAsEKIRNLEEQRESQEK 473
Cdd:PTZ00121 1086 DNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKA-EEARKA-EDAKRVEIARKAEDA 1163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  474 LTISVQNSLNEAhRQHKQFIEELMIRHREELKEREDSHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGD 553
Cdd:PTZ00121 1164 RKAEEARKAEDA-KKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEA 1242

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  554 VAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEGEGKL 633
Cdd:PTZ00121 1243 KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKK 1322

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  634 NQEQFLESKNELNTLTDQIESlNSEVENKNEEIRNLMATLQEKEVHIQNVRTsshqltatyEEANGEIDILKAELtrlhe 713
Cdd:PTZ00121 1323 KAEEAKKKADAAKKKAEEAKK-AAEAAKAEAEAAADEAEAAEEKAEAAEKKK---------EEAKKKADAAKKKA----- 1387

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  714 qvnERTRQISEANEKYDDAARKNDAlLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRAllddlrgnfdkltNELK 793
Cdd:PTZ00121 1388 ---EEKKKADEAKKKAEEDKKKADE-LKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKA-------------DEAK 1450

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  794 QKGvtvdslnEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEKDRQGVENFGKECEARMNELTKI 873
Cdd:PTZ00121 1451 KKA-------EEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKK 1523

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  874 HEMLMEEHDQLKVDHLHTEEEVERLKE-KMRKELEKLNEQNDGDRAEWSNERNRLESSKNEAVTELQERvqKLEDVVKEK 952
Cdd:PTZ00121 1524 ADEAKKAEEAKKADEAKKAEEKKKADElKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEA--RIEEVMKLY 1601

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  953 EDkEIALRRDLEDSHEKSRDLDDKLRKMEltdeEKEEDRKKEQKTLNEERMKLMEQKEEAMLVATKHAttidQQTRRISV 1032
Cdd:PTZ00121 1602 EE-EKKMKAEEAKKAEEAKIKAEELKKAE----EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAA----EEAKKAEE 1672

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1033 LEGDVEKLTAGIAERESSINALESNTMElISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERKKIQDLAD 1112
Cdd:PTZ00121 1673 DKKKAEEAKKAEEDEKKAAEALKKEAEE-AKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKK 1751

                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|.
gi 133903949 1113 QLREANKVVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKN 1163
Cdd:PTZ00121 1752 DEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKD 1802
PTZ00121 PTZ00121
MAEBL; Provisional
 273-976 9.81e-15

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 80.57  E-value: 9.81e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  273 RQLTEFTRCATLMRKAIRHAEQKNLDQKEQMKREKDDVLDETLRQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQ 352
Cdd:PTZ00121 1296 KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE 1375

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  353 NDELSDILEQLSKMAHEMAGGRGRNETPMDVARKMRKllttKNGEIDESREAAKQAEKER--DRAKKDLEKEEKRRKDDR 430
Cdd:PTZ00121 1376 AKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKK----AAAAKKKADEAKKKAEEKKkaDEAKKKAEEAKKADEAKK 1451

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  431 EAERKRSSVYSQREHDLKKLDDELRKASEKIRNLEEQRESQEKLTisvqnslneahrqhkqfieelmiRHREELKEREDS 510
Cdd:PTZ00121 1452 KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAK-----------------------KKADEAKKAAEA 1508

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  511 HEEALRSKDTEERSRFEKERSEREKirRESDELRETQRSLKGDVAAMKTDLDDKTlrldmlETERDELKKKLETEREQAD 590
Cdd:PTZ00121 1509 KKKADEAKKAEEAKKADEAKKAEEA--KKADEAKKAEEKKKADELKKAEELKKAE------EKKKAEEAKKAEEDKNMAL 1580

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  591 QRDLEIAECRAKLDEMAEKEAELRKELAEFQAiitAMEGEGKLNQEQfLESKNELNTLTDQIESLNSEVENKNEEIRNlm 670
Cdd:PTZ00121 1581 RKAEEAKKAEEARIEEVMKLYEEEKKMKAEEA---KKAEEAKIKAEE-LKKAEEEKKKVEQLKKKEAEEKKKAEELKK-- 1654

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  671 atlQEKEVHIQnvrtsshqltATYEEANGEIDILKAELTRLHEqvnERTRQISEANEKYDDAARKNDALLEDVATWQEKY 750
Cdd:PTZ00121 1655 ---AEEENKIK----------AAEEAKKAEEDKKKAEEAKKAE---EDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKA 1718

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  751 EQLKMELEEMNRRGQEKEREEADLRALLDDLRGNfDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKeeLLRMEEL 830
Cdd:PTZ00121 1719 EELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEE--DEKRRME 1795

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  831 EQKNEAEMKEEYEVkLQLAEKDRQGVENFGKECE-ARMNELTKIHEMLMEEHDQL-KVDHLHTEEEVERLKEKMRKELEK 908
Cdd:PTZ00121 1796 VDKKIKDIFDNFAN-IIEGGKEGNLVINDSKEMEdSAIKEVADSKNMQLEEADAFeKHKFNKNNENGEDGNKEADFNKEK 1874

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 133903949  909 LNEQNDGDRAEWSNERNRLESSKNEAVTELQERVQKLEDVVKEKEDKEIALRRDLEDSHEKSRDLDDK 976
Cdd:PTZ00121 1875 DLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIKRDAEETREEIIKISKK 1942
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 424-1040 1.38e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.60  E-value: 1.38e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  424 KRRKddREAERKRSSVysqrEHDLKKLDD---ELRKaseKIRNLEEQRESQEKLTisvqnSLNEAHRQHKQFIEELMIRH 500
Cdd:COG1196   171 KERK--EEAERKLEAT----EENLERLEDilgELER---QLEPLERQAEKAERYR-----ELKEELKELEAELLLLKLRE 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  501 REELKEREDSHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKK 580
Cdd:COG1196   237 LEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE 316

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  581 KLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEgegklnqEQFLESKNELNTLTDQIESLNSEVE 660
Cdd:COG1196   317 RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE-------EALLEAEAELAEAEEELEELAEELL 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  661 NKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALL 740
Cdd:COG1196   390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  741 EDVATWQEKYEQLKMELEEMNRRGQEKEREEAD---------LRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKE 811
Cdd:COG1196   470 EEAALLEAALAELLEELAEAAARLLLLLEAEADyegflegvkAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQ 549

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  812 QLNKSEKERKEELLRMEELEQKNEAE--MKEEYEVKLQLAEKDRQGVENFGKECEARMNELTKIHEMLMEEHDQLKVDHL 889
Cdd:COG1196   550 NIVVEDDEVAAAAIEYLKAAKAGRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA 629

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  890 HTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERnRLESSKNEAVTELQERVQKLEDVVKEKEDKEIALRRDLEDSHEK 969
Cdd:COG1196   630 ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTG-GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 133903949  970 SRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEEAMLVATKHATTIDQQTRRISVLEGDVEKL 1040
Cdd:COG1196   709 LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 435-1137 2.37e-14

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 78.91  E-value: 2.37e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   435 KRSSVYSQREHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQFIEELMIRHREELKEREDSHEEA 514
Cdd:TIGR04523   30 KQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKIN 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   515 LRSK-DTEERSRFEKERSEREKIRRESDELretQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRD 593
Cdd:TIGR04523  110 SEIKnDKEQKNKLEVELNKLEKQKKENKKN---IDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQ 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   594 LEIAECRAKLdemaekeaeLRKELAEFqaIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIrnlmatl 673
Cdd:TIGR04523  187 KNIDKIKNKL---------LKLELLLS--NLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEI------- 248

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   674 QEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDAARKNdaLLEDVATWQEKYEQL 753
Cdd:TIGR04523  249 SNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKE--LKSELKNQEKKLEEI 326

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   754 KMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKErkeellrmeeleqk 833
Cdd:TIGR04523  327 QNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQ-------------- 392

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   834 neaemKEEYEVKLQLAEKDRQgvenfgkECEARMNELTKIHEMLMEEHDQLKVDHLHTEEEVERLKEKMrKELEKLNEQN 913
Cdd:TIGR04523  393 -----INDLESKIQNQEKLNQ-------QKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQD-SVKELIIKNL 459

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   914 DGDRAEWSNERNRLESSKNEAVTELQERVQKLedvvKEKEDKEIALRRDLEDSHEKSRDLDDKLRKMELTDEEKEEDRKK 993
Cdd:TIGR04523  460 DNTRESLETQLKVLSRSINKIKQNLEQKQKEL----KSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKE 535

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   994 EQKTLNEERMKLMEQKEEamLVATKHATTIDQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAELE 1073
Cdd:TIGR04523  536 KESKISDLEDELNKDDFE--LKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKIS 613

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 133903949  1074 KLKDELAVMLKQNSELKNGKEGLSEKWNEERKKIQDLADQLREANKVVHNMRMKNVNLEEKKNE 1137
Cdd:TIGR04523  614 SLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDD 677
PTZ00121 PTZ00121
MAEBL; Provisional
 452-1249 5.65e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 78.26  E-value: 5.65e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  452 DELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQFIEELMIRHREELKEREDSH--EEALRSKDT---EERSRF 526
Cdd:PTZ00121 1069 DEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARkaEEARKAEDArkaEEARKA 1148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  527 EKERseREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAEcraKLDEM 606
Cdd:PTZ00121 1149 EDAK--RVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEAR---KAEDA 1223

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  607 AEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTS 686
Cdd:PTZ00121 1224 KKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKK 1303

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  687 SHQLTATYEEANgeidilKAEltRLHEQVNERTRQISEANEKYDDAARKndallEDVATWQEKYEQLKMELEEMNRRGQE 766
Cdd:PTZ00121 1304 ADEAKKKAEEAK------KAD--EAKKKAEEAKKKADAAKKKAEEAKKA-----AEAAKAEAEAAADEAEAAEEKAEAAE 1370

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  767 KEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKL 846
Cdd:PTZ00121 1371 KKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAK 1450

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  847 QLAEKDRQGVENFGKECEARMNELTKIHEMLMEEHDQLKVDHLHTEEEVERLKEKmRKELEKLNEQNDGDRAEWSNERNR 926
Cdd:PTZ00121 1451 KKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKA-AEAKKKADEAKKAEEAKKADEAKK 1529

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  927 LESSKNEAVTELQERVQKLEDVVKEKEDKEIALRRDLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLM 1006
Cdd:PTZ00121 1530 AEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1007 EQKEEAmlvatKHATTIDQQTRRISVLEGDVEKLTAGIAERessinalesntmelISKLETTEAELEKLKDELAVMLKQN 1086
Cdd:PTZ00121 1610 EEAKKA-----EEAKIKAEELKKAEEEKKKVEQLKKKEAEE--------------KKKAEELKKAEEENKIKAAEEAKKA 1670

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1087 SELKNGKEGLSEKWNEERKKIQDLADQLREANKvVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEiqlmDKAAKNEVS 1166
Cdd:PTZ00121 1671 EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK-AEELKKKEAEEKKKAEELKKAEEENKIKAEEAK----KEAEEDKKK 1745

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1167 GDLLRKMEHDAQSMLKQAQNEQFRLTDLEKVRKALQDENqrlvndlatVKAAFEVKRETSKSAISDILDKYRSAEEKANK 1246
Cdd:PTZ00121 1746 AEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE---------LDEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816


                  ...
gi 133903949 1247 GEL 1249
Cdd:PTZ00121 1817 GNL 1819
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 501-1205 5.76e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 77.80  E-value: 5.76e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   501 REELKEREDSHE--EALRSKDTEERSRFEKERSEREKIRRESDELRETQRSLK-GDVAAMKTDLDDKTLRLDMLETERDE 577
Cdd:TIGR02169  176 LEELEEVEENIErlDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELlKEKEALERQKEAIERQLASLEEELEK 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   578 LKKKLETEREQADQRDLEIAECRAKLDEMAEKEA-ELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLN 656
Cdd:TIGR02169  256 LTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQlRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   657 SEVENKNEEIrnlmatlqekevhiQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDAARKN 736
Cdd:TIGR02169  336 AEIEELEREI--------------EEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   737 DALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKS 816
Cdd:TIGR02169  402 NELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRV 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   817 EKERKEELLRMEELEQKNEAEMKEEYEVKLQ--LAEKDRQGV-----------ENFGKECE----ARMNELTKIHEMLME 879
Cdd:TIGR02169  482 EKELSKLQRELAEAEAQARASEERVRGGRAVeeVLKASIQGVhgtvaqlgsvgERYATAIEvaagNRLNNVVVEDDAVAK 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   880 EHDQLKVDH---------LHTEEEVERLKEKMRKE--------------------------------LEKLNEQN----- 913
Cdd:TIGR02169  562 EAIELLKRRkagratflpLNKMRDERRDLSILSEDgvigfavdlvefdpkyepafkyvfgdtlvvedIEAARRLMgkyrm 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   914 ---DGDRAEWS-------NERNRLESSKNEAVTELQERVQKLEDVVKEKEDKEIALRRDLEDSHEKSRDLDDKLRKMELT 983
Cdd:TIGR02169  642 vtlEGELFEKSgamtggsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEI 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   984 DEEKEEdrkkeqktLNEERMKLMEQKEEAMLVATKHATTIDQQTRRISVLEGDVEKLTAGIAERESSINALESntMELIS 1063
Cdd:TIGR02169  722 EKEIEQ--------LEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA--RLSHS 791

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1064 KLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERKKIQDLADQLREANKVVHNMRMKNVNLEEKKNELDQNVT 1143
Cdd:TIGR02169  792 RIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELE 871

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 133903949  1144 DLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNEQFRLTDLEKVRKALQDEN 1205
Cdd:TIGR02169  872 ELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL 933
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 385-954 6.63e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.67  E-value: 6.63e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  385 RKMRKLLTTKNGEIDESREAAKQAEKERDRAKKDLEKEEKRRKDDREAERKRSSVYSQREHDLKKLDDELRKASEKIRNL 464
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  465 EEQRESQEKltisVQNSLNEAHRQHKQFIEELMIRHREELKEREDSHEEALRSKDTEERSRFEKERSEREKIRRESDELR 544
Cdd:COG1196   315 EERLEELEE----ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  545 ETQR--SLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQA 622
Cdd:COG1196   391 ALRAaaELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLE 470

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  623 IITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHI-QNVRTSSHQLTATYEEANGEI 701
Cdd:COG1196   471 EAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVlIGVEAAYEAALEAALAAALQN 550

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  702 DILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVATWQEKY-----EQLKMELEEMNRRGQEKEREEADLRA 776
Cdd:COG1196   551 IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAavdlvASDLREADARYYVLGDTLLGRTLVAA 630

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  777 LLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEKDRQgv 856
Cdd:COG1196   631 RLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE-- 708

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  857 enfgkecEARMNELTKIHEMLMEEHDQLKVDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRLESSKN---- 932
Cdd:COG1196   709 -------LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEalgp 781

                         570       580       590
                  ....*....|....*....|....*....|..
gi 133903949  933 ------EAVTELQER----VQKLEDVVKEKED 954
Cdd:COG1196   782 vnllaiEEYEELEERydflSEQREDLEEARET 813
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
294-797 6.76e-14

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 77.39  E-value: 6.76e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  294 QKNLDQKEQMKREKDDVLD---ETLRQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQL------- 363
Cdd:PRK02224  226 EEQREQARETRDEADEVLEeheERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLlaeagld 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  364 ----SKMAHEMAGGRGRNETPMDVARKMRKLLTTKNGEIDESREAAKQAEKERDrakkdlEKEEKRRKDDREAERKRSSV 439
Cdd:PRK02224  306 dadaEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAE------ELREEAAELESELEEAREAV 379

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  440 ySQREHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQFIEEL-----MIRHREELKEREDSHEEA 514
Cdd:PRK02224  380 -EDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLrtareRVEEAEALLEAGKCPECG 458

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  515 LRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAMKtDLDDKTLRLDMLETERDELKKKLETEREQADQRDL 594
Cdd:PRK02224  459 QPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAE-DLVEAEDRIERLEERREDLEELIAERRETIEEKRE 537

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  595 EIAECRAKLDEMAEKEAELRKELAEF-QAIITAMEGEGKLNQEQF-----LESKNELNTLTDQIESLNSEVENKNEEIRN 668
Cdd:PRK02224  538 RAEELRERAAELEAEAEEKREAAAEAeEEAEEAREEVAELNSKLAelkerIESLERIRTLLAAIADAEDEIERLREKREA 617

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  669 LMATLQEKEVHIQNVRTSSHQLTATYEEANgeIDILKAELTRLHEqvnertrQISEANEKYDDAARKNDALLEDVATWQE 748
Cdd:PRK02224  618 LAELNDERRERLAEKRERKRELEAEFDEAR--IEEAREDKERAEE-------YLEQVEEKLDELREERDDLQAEIGAVEN 688

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 133903949  749 KYEQLKMELEEMNRRGQEKEREEAdLRALLDDLRGNFDKLTNELKQKGV 797
Cdd:PRK02224  689 ELEELEELRERREALENRVEALEA-LYDEAEELESMYGDLRAELRQRNV 736
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 411-788 7.39e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.40  E-value: 7.39e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   411 ERDRAKKDLEKEEKRRKDD-REAERKRSSVYSQREHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQH 489
Cdd:TIGR02168  674 ERRREIEELEEKIEELEEKiAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLS 753

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   490 KQfIEELMIRHREELKEREDSHEEALRSKDteersRFEKERSEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLD 569
Cdd:TIGR02168  754 KE-LTELEAEIEELEERLEEAEEELAEAEA-----EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLE 827

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   570 MLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLT 649
Cdd:TIGR02168  828 SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELE 907

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   650 DQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTS-SHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISE---- 724
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKElgpv 987

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 133903949   725 ---ANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKereeadLRALLDDLRGNFDKL 788
Cdd:TIGR02168  988 nlaAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARER------FKDTFDQVNENFQRV 1048
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 350-1107 1.29e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 76.65  E-value: 1.29e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   350 REQNDELSDILEQLSKMAHEMAGGRGRNETPMDVARKMRKL-LTTKNGEIDESREAAKQAEKERDRAKKDLEKEEKRRKD 428
Cdd:TIGR02169  183 EENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYeGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISE 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   429 DREAERKRSSVYSQREHDLKKL-DDELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQFIEELmirhreelkER 507
Cdd:TIGR02169  263 LEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEI---------DK 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   508 EDSHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETERE 587
Cdd:TIGR02169  334 LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   588 QADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIR 667
Cdd:TIGR02169  414 ELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELA 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   668 NLMATLQ--------------EKEVHIQNVRTSSHQLTATYEEANGEIDIlkAELTRLHEQVNE------------RTRQ 721
Cdd:TIGR02169  494 EAEAQARaseervrggraveeVLKASIQGVHGTVAQLGSVGERYATAIEV--AAGNRLNNVVVEddavakeaiellKRRK 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   722 ISEA----------NEKYDDAARKNDAL--LEDVATWQEKYE-------------------------------------- 751
Cdd:TIGR02169  572 AGRAtflplnkmrdERRDLSILSEDGVIgfAVDLVEFDPKYEpafkyvfgdtlvvedieaarrlmgkyrmvtlegelfek 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   752 -------------------QLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQ 812
Cdd:TIGR02169  652 sgamtggsraprggilfsrSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQE 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   813 LNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEKDRQgvenfgkeCEARMNELTKIHEMLMEEHDQLKVDHLHT- 891
Cdd:TIGR02169  732 EEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEED--------LHKLEEALNDLEARLSHSRIPEIQAELSKl 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   892 EEEVERLKEKMR------KELEKLNEQNDGDRAEWSNERNRLESSKNE---AVTELQERVQKLEDVVKEKEDKEIALRRD 962
Cdd:TIGR02169  804 EEEVSRIEARLReieqklNRLTLEKEYLEKEIQELQEQRIDLKEQIKSiekEIENLNGKKEELEEELEELEAALRDLESR 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   963 LEDSHEKSRDLDDKLRKMEltdeeKEEDRKKEQKTLNEERMKLMEQKEEAMLVATKHATTIDQQTRRISVLEGDVEKLTA 1042
Cdd:TIGR02169  884 LGDLKKERDELEAQLRELE-----RKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQA 958

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 133903949  1043 GIAERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNgkegLSEKWNEERKKI 1107
Cdd:TIGR02169  959 ELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILE----RIEEYEKKKREV 1019
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 308-952 1.39e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.51  E-value: 1.39e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  308 DDVLDETLRQLNS------VTENYMKSEEKANERQRDL-----KRKEDECRKLREQNDELSDILEQLSKMAHEMAGGRgr 376
Cdd:COG1196   192 EDILGELERQLEPlerqaeKAERYRELKEELKELEAELlllklRELEAELEELEAELEELEAELEELEAELAELEAEL-- 269

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  377 netpmdvaRKMRKLLTTKNGEIDESREAAKQAEKERDRAKKDLEKEEKRRKDDREAERKRSSVYSQREHDLKKLDDELRK 456
Cdd:COG1196   270 --------EELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEE 341

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  457 ASEKIRNLEEQRESQEKLTISVQNSLNEAHRQhkqfieelmIRHREELKEREDSHEEALRSKDTEERSRFEKERSEREKI 536
Cdd:COG1196   342 LEEELEEAEEELEEAEAELAEAEEALLEAEAE---------LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEAL 412

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  537 RRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKE 616
Cdd:COG1196   413 LERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  617 LAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEE 696
Cdd:COG1196   493 LLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAG 572

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  697 ANGEIDILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVATWQEkyEQLKMELEEMNRRGQEKEREEADLRA 776
Cdd:COG1196   573 RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLG--RTLVAARLEAALRRAVTLAGRLREVT 650

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  777 LLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEKDRQGV 856
Cdd:COG1196   651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  857 ENFGKECEARMNELTKIHEMLMEEHDQLKVDHLHTEEEVERLKEKMRK----------ELEKLNEQNDgdraEWSNERNR 926
Cdd:COG1196   731 EAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAlgpvnllaieEYEELEERYD----FLSEQRED 806

                         650       660
                  ....*....|....*....|....*.
gi 133903949  927 LEssknEAVTELQERVQKLEDVVKEK 952
Cdd:COG1196   807 LE----EARETLEEAIEEIDRETRER 828
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 393-952 2.74e-13

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 75.44  E-value: 2.74e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   393 TKNGEIDESREAAKQAEKERDRAKKDLEKEEKRRKDDREAERKRSSVYSQREHDLKKLDDELRKASEKIRNLEEQReSQE 472
Cdd:TIGR04523  121 KLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKL-LKL 199

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   473 KLTISVQNSLNEAHRQHKQFIEELmIRHREELKEREDSHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKg 552
Cdd:TIGR04523  200 ELLLSNLKKKIQKNKSLESQISEL-KKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELE- 277

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   553 dvaAMKTDLDDKTLRLDMLETERDELKKKLETE-----REQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIITAM 627
Cdd:TIGR04523  278 ---QNNKKIKELEKQLNQLKSEISDLNNQKEQDwnkelKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNS 354

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   628 EGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAE 707
Cdd:TIGR04523  355 ESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKET 434

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   708 LTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDK 787
Cdd:TIGR04523  435 IIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKD 514

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   788 LTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLA----EKDRQGVENFGKEC 863
Cdd:TIGR04523  515 LTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTqkslKKKQEEKQELIDQK 594

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   864 EARMNELTKIHEMLMEEHDQLKVDHLHTEEEVERL----------KEKMRKELEKLNEQNDGDRAEWSNernrLESSKNE 933
Cdd:TIGR04523  595 EKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLssiiknikskKNKLKQEVKQIKETIKEIRNKWPE----IIKKIKE 670

                          570
                   ....*....|....*....
gi 133903949   934 AVTELQERVQKLEDVVKEK 952
Cdd:TIGR04523  671 SKTKIDDIIELMKDWLKEL 689
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 893-1714 2.87e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.49  E-value: 2.87e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   893 EEVERLKEKMRKELEKLNEQNDGDRA---EWSNERNRLESSKNEAV--TELQERVQKLEDVVKEKEDKeiALRRDLEDSH 967
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLiidEKRQQLERLRREREKAEryQALLKEKREYEGYELLKEKE--ALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   968 EKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEEAMLvatkhattidQQTRRISVLEGDVEKLTAGIAER 1047
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQL----------RVKEKIGELEAEIASLERSIAEK 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1048 ESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERKKIQDLADQLREANKVVHNMRMK 1127
Cdd:TIGR02169  314 ERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1128 NVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNEQFRLTDLEKVRKALQDENQR 1207
Cdd:TIGR02169  394 LEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYD 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1208 LVNDLATVKAAFEVKR------ETSKSAISDILDKYRSAEEKANKGELDNQRLRSDLATVtlklERQELKAKDS--DNRL 1279
Cdd:TIGR02169  474 LKEEYDRVEKELSKLQrelaeaEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSV----GERYATAIEVaaGNRL 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1280 RDSQKRFEEVQSKLANLQKSAVESLQNPMSSNSRQNRSIYVDIPRAASSIGLNENSDEVPLRSSPSVRFADSS----QNM 1355
Cdd:TIGR02169  550 NNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDtlvvEDI 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1356 QRAVDSMD------------------------------VSSSVGVTLRFLKERIEQLEADNADLSDALEKAKDELRQRNE 1405
Cdd:TIGR02169  630 EAARRLMGkyrmvtlegelfeksgamtggsraprggilFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1406 KLADRQMVIERVERQLVHITEERNTIENRMT------SQRQMYLTNEESSRSR-EHEIRSMKARISTLELHLREKESKLA 1478
Cdd:TIGR02169  710 ELSDASRKIGEIEKEIEQLEQEEEKLKERLEeleedlSSLEQEIENVKSELKElEARIEELEEDLHKLEEALNDLEARLS 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1479 H-------------------LRKEIEVLHGQLHDALESKEKATGLVGVQDSKHRDLEEQLDRANRERELAIGKQRRTLAE 1539
Cdd:TIGR02169  790 HsripeiqaelskleeevsrIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEE 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1540 NENLFRKLEQLEKEREQLMREITD---ERRLNERNRTSLEELRVSERTWKSAMTTAKKPAEEQERAVQEQRRWEESNHEM 1616
Cdd:TIGR02169  870 LEELEAALRDLESRLGDLKKERDEleaQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEE 949

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1617 TNRNTALTKECDRLRVEMRDqlnrMNGINLRsvdferkneelssklivmqntvtAMKKFEEEWKRLE--AEMRAELKILR 1694
Cdd:TIGR02169  950 ELSLEDVQAELQRVEEEIRA----LEPVNML-----------------------AIQEYEEVLKRLDelKEKRAKLEEER 1002

                          890       900
                   ....*....|....*....|
gi 133903949  1695 KEKLMQTAEIEDLKRKSFRS 1714
Cdd:TIGR02169 1003 KAILERIEEYEKKKREVFME 1022
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 350-932 4.85e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 74.77  E-value: 4.85e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   350 REQNDELSDILEQLSKMAHEMAGGRGRNETPMDVAR----KMRKLLTTKNGEIDESREAAKQAEKERDRakkdlekeeKR 425
Cdd:pfam15921  134 RRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNtqieQLRKMMLSHEGVLQEIRSILVDFEEASGK---------KI 204

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   426 RKDDREAERKRSSVYSQREHDLKKLDDELRKASEKIRNLEEQRESqekLTISVQNSLNEAHRQHKQFIEELMIRHREE-- 503
Cdd:pfam15921  205 YEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEA---LKSESQNKIELLLQQHQDRIEQLISEHEVEit 281

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   504 -LKEREDSHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDM-----------L 571
Cdd:pfam15921  282 gLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKqlvlanselteA 361

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   572 ETERDEL---------------------KKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEGE 630
Cdd:pfam15921  362 RTERDQFsqesgnlddqlqklladlhkrEKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSE 441

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   631 GKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTR 710
Cdd:pfam15921  442 CQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITK 521

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   711 LHEQVNERTRQiseanekyddaarkndalLEDVATWQEKYEQLKMELEEMNRRGQEKEReeadlraLLDDLRGNFDKLTN 790
Cdd:pfam15921  522 LRSRVDLKLQE------------------LQHLKNEGDHLRNVQTECEALKLQMAEKDK-------VIEILRQQIENMTQ 576

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   791 ELKQKGVTVDSLNEEisslKEQLNKSEKERKEELLRMEELEQKNEAEMKeEYEVKLQLAEKDRQGVENFGKECEARMNEL 870
Cdd:pfam15921  577 LVGQHGRTAGAMQVE----KAQLEKEINDRRLELQEFKILKDKKDAKIR-ELEARVSDLELEKVKLVNAGSERLRAVKDI 651

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 133903949   871 TKIHEMLMEEHDQLKVDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRLESSKN 932
Cdd:pfam15921  652 KQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRN 713
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 356-1243 6.41e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 74.33  E-value: 6.41e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   356 LSDILEQLSKMAHEMAG----------------GRGRNETPMDVA------RKMRKLLttknGEIDESREAAKQAE---- 409
Cdd:TIGR02169  119 LSEIHDFLAAAGIYPEGynvvlqgdvtdfismsPVERRKIIDEIAgvaefdRKKEKAL----EELEEVEENIERLDliid 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   410 ---KERDRAKKDLEKEEKRRKDDREAERKRSSVYSQR----EHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQNSL 482
Cdd:TIGR02169  195 ekrQQLERLRREREKAERYQALLKEKREYEGYELLKEkealERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLL 274

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   483 NEAHRQHKQFIEELMIRHREELKEREDSHEEALRSKDTEERsrfekersEREKIRRESDELRETQRSLKGDVAAMKTDLD 562
Cdd:TIGR02169  275 EELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKER--------ELEDAEERLAKLEAEIDKLLAEIEELEREIE 346

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   563 DKTLRLDMLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESK 642
Cdd:TIGR02169  347 EERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLN 426

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   643 NELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQ---VNERT 719
Cdd:TIGR02169  427 AAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQaraSEERV 506

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   720 RQISEANEKYDDAARKNDALLEDVATWQEKYeQLKMELEEMNRRGQEKEREEADLRALLDDLRgnfdkltnELKQKGVTV 799
Cdd:TIGR02169  507 RGGRAVEEVLKASIQGVHGTVAQLGSVGERY-ATAIEVAAGNRLNNVVVEDDAVAKEAIELLK--------RRKAGRATF 577

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   800 DSLNEeisslkeqLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEKDRQGVENF--GKECEARMNELTKIHEML 877
Cdd:TIGR02169  578 LPLNK--------MRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIeaARRLMGKYRMVTLEGELF 649

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   878 MEE------HDQLKVDHLHTEEEVERLkEKMRKELEKLneqnDGDRAEWSNERNRLESSKNEAVTELQERVQKLEDVVKE 951
Cdd:TIGR02169  650 EKSgamtggSRAPRGGILFSRSEPAEL-QRLRERLEGL----KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKE 724

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   952 KEdkeiALRRDLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLME-QKEEAMLVATKHATTIDQQTRRI 1030
Cdd:TIGR02169  725 IE----QLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKlEEALNDLEARLSHSRIPEIQAEL 800

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1031 SVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERKKIQDL 1110
Cdd:TIGR02169  801 SKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDL 880

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1111 ADQLREANKVVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNEQFR 1190
Cdd:TIGR02169  881 ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAEL 960

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 133903949  1191 LTDLEKVRkALQDENQRLVNDLATVKAAF---EVKRETSKSAISDILDKYRSAEEK 1243
Cdd:TIGR02169  961 QRVEEEIR-ALEPVNMLAIQEYEEVLKRLdelKEKRAKLEEERKAILERIEEYEKK 1015
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1375-1862 1.18e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.43  E-value: 1.18e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1375 LKERIEQLEADNADLSDALEKAKDELRQRNEKLADRQMVIERVERQLVHITEERNTIENRMTSQRQMYLTNEESSRSREH 1454
Cdd:COG1196   244 LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEE 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1455 EIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDALESKEKATGLVGVQDSKHRDLEEQLDRANRERELAIGKQR 1534
Cdd:COG1196   324 ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1535 RTLAENENLFRKLEQLEKEREQLMREITDERRLNERNRTSLEELRVSERTWKSAMTTAKKPAEEQERAVQEQRRweesnh 1614
Cdd:COG1196   404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA------ 477

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1615 emtnRNTALTKECDRLRVEMRDQLNRMNGINLRSVDFERKNEELSSKLIVMQNTVTAMKKFEEEWKRLEAEMRAELKILR 1694
Cdd:COG1196   478 ----ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVV 553

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1695 KEKLMQTAEIEDLKRKS------FRSDTEKKEIEGIRVRLEREISALKRHVDALEEEKGKTEKAVRETMNERRAIDKSLA 1768
Cdd:COG1196   554 EDDEVAAAAIEYLKAAKagratfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLE 633

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1769 S---MERENQQLYRNCAQLQAQIQNLERDAGNRSVTKLAKEHSLLEARIAALIEEKRQLQSMLDQKDANYSHKRKLLESQ 1845
Cdd:COG1196   634 AalrRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                         490
                  ....*....|....*..
gi 133903949 1846 IQLLREQLEAERRKRTK 1862
Cdd:COG1196   714 EERLEEELEEEALEEQL 730
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1028-1583 1.93e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.66  E-value: 1.93e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1028 RRISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERKKI 1107
Cdd:COG1196   232 LKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERR 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1108 QDLADQLREANKVVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNE 1187
Cdd:COG1196   312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA 391

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1188 QFRLTDLEKVRKALQDENQRLVNDLATVKAAFEVKRETSKSAISDILDKYRSAEEKANKGELDNQRLRSDLATVTLKLER 1267
Cdd:COG1196   392 LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1268 QELKAKDSDNRLRDSQKRFEEVQSKLANLQKSAVESLQNPMSSNSRQNRSIYVDIPRAASSIGLNENSDEVPLRSSPSVR 1347
Cdd:COG1196   472 AALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNI 551

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1348 FADSSQNMQRAVDSMDVSSSVGVT-----------LRFLKERIEQLEADNADLSDALEKAKDELRQRNEKLADRQMVIER 1416
Cdd:COG1196   552 VVEDDEVAAAAIEYLKAAKAGRATflpldkiraraALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAAR 631

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1417 VERQLVHITEERNTIENRMTSQRQMYLTNEESSRSREHEIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDALE 1496
Cdd:COG1196   632 LEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAE 711

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1497 SKEKATGLVGVQDSKHRDLEEQLDRANRERELAIGKQRRTLAENENLFRKLEQLEKEREQLMREItdeRRLNERNRTSLE 1576
Cdd:COG1196   712 AEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI---EALGPVNLLAIE 788


                  ....*...
gi 133903949 1577 EL-RVSER 1583
Cdd:COG1196   789 EYeELEER 796
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 940-1744 2.23e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.78  E-value: 2.23e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   940 ERVQKLEDVVKEKEDKEIALR-RDLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEEamlvatk 1018
Cdd:TIGR02168  210 EKAERYKELKAELRELELALLvLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE------- 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1019 hattIDQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSE 1098
Cdd:TIGR02168  283 ----IEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1099 KWNEERKKIQDLADQLREANKVVHNMRmknvnleEKKNELDQNVTDLTNKVRQLEIQLmdKAAKNEVSGDLLRKMEHDAQ 1178
Cdd:TIGR02168  359 ELEELEAELEELESRLEELEEQLETLR-------SKVAQLELQIASLNNEIERLEARL--ERLEDRRERLQQEIEELLKK 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1179 SMLKQAQNEQFRLTDLEKVRKALQDENQRLVNDLATVKAAFEVKREtsksaisdILDKYRSAEEKANKGELDNQRLRSDL 1258
Cdd:TIGR02168  430 LEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQ--------ALDAAERELAQLQARLDSLERLQENL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1259 ATVTlKLERQELKAKDSDNRLRDSQKRFEEVQSKLAN-LQKSAVESLQNPMSSNSRQnrsiyvdiprAASSIGLNENSDE 1337
Cdd:TIGR02168  502 EGFS-EGVKALLKNQSGLSGILGVLSELISVDEGYEAaIEAALGGRLQAVVVENLNA----------AKKAIAFLKQNEL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1338 VPLRSSPSVRFADSSQNmqraVDSMDVSSSVGVTLRFLKERIEQLEADNADLSDAL------EKAKDELRQRNEKlaDRQ 1411
Cdd:TIGR02168  571 GRVTFLPLDSIKGTEIQ----GNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvDDLDNALELAKKL--RPG 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1412 MVIERVERQLVH----ITEERNTIENRMTSQRQMYLTNEESSRSREHEIRSMKARISTLELHLREKESKLAHLRKEIEVL 1487
Cdd:TIGR02168  645 YRIVTLDGDLVRpggvITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1488 HGQLHDALESKEKATGLVGVQDSKHRDLEEQLDRANRERELAIGKQRRTLAENENLFRKLEQLEKEREQLMREITDERRL 1567
Cdd:TIGR02168  725 SRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREA 804

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1568 NERNRTSLEELRVSERTWKSAMTTAKKPAEEQERAVQE-QRRWEESNHEMTNRN---TALTKECDRLRVEMRDQLNRMNG 1643
Cdd:TIGR02168  805 LDELRAELTLLNEEAANLRERLESLERRIAATERRLEDlEEQIEELSEDIESLAaeiEELEELIEELESELEALLNERAS 884

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1644 INLRSVDFERKNEELSSKLIVMQNTVTAMKKFEEEWKRLEAEMRAELKILR------KEKLMQTAEI--EDLKRKSFRSD 1715
Cdd:TIGR02168  885 LEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEvridnlQERLSEEYSLtlEEAEALENKIE 964

                          810       820       830
                   ....*....|....*....|....*....|
gi 133903949  1716 TEKKEIEGIRVRLEREISALKR-HVDALEE 1744
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKELGPvNLAAIEE 994
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 252-912 4.51e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 71.64  E-value: 4.51e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   252 EFTAVKRQLHELRTTTANdLDRQLTEFTRCATLMRKAIRHAEQKnLDQKEQMKREKDDVLDETLRQLNSVTENYMKSEEK 331
Cdd:TIGR02169  288 EQLRVKEKIGELEAEIAS-LERSIAEKERELEDAEERLAKLEAE-IDKLLAEIEELEREIEEERKRRDKLTEEYAELKEE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   332 ANERQRDLkrkEDECRKLREQNDELSDILEQLSKMAHEMAGGRGRNETPMDVARKMRKLLTTKNGEIDESREAAKQAEKE 411
Cdd:TIGR02169  366 LEDLRAEL---EEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEE 442

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   412 RDRAKKDLEKEEKRRKDDREAERKRSSVYSQREHDLKKLDDELRKASEKIRNLEEQR---ESQEKLTISVQNSLNEAHRQ 488
Cdd:TIGR02169  443 KEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQArasEERVRGGRAVEEVLKASIQG 522

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   489 HKQFIEELMIRHREELKEREDSHEEALRS------KDTEERSRFEKERS-------EREKIRRESDELRETQRSLKGDVA 555
Cdd:TIGR02169  523 VHGTVAQLGSVGERYATAIEVAAGNRLNNvvveddAVAKEAIELLKRRKagratflPLNKMRDERRDLSILSEDGVIGFA 602

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   556 AMKTDLDDK-----------TLRLDMLETERD------------------------------------ELKKKLETEREQ 588
Cdd:TIGR02169  603 VDLVEFDPKyepafkyvfgdTLVVEDIEAARRlmgkyrmvtlegelfeksgamtggsraprggilfsrSEPAELQRLRER 682

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   589 ADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRN 668
Cdd:TIGR02169  683 LEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKE 762

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   669 LMATLQEKEVHIQNVRTSSHQLTATY-----EEANGEIDILKAELTRLHEQVNERTRQISE-------ANEKYDDAARKN 736
Cdd:TIGR02169  763 LEARIEELEEDLHKLEEALNDLEARLshsriPEIQAELSKLEEEVSRIEARLREIEQKLNRltlekeyLEKEIQELQEQR 842

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   737 DALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLnKS 816
Cdd:TIGR02169  843 IDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL-SE 921

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   817 EKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEkdrqgVENFGKECEARMNELTKIHEMLMEEHDQLKVDHLHTEEEVE 896
Cdd:TIGR02169  922 LKAKLEALEEELSEIEDPKGEDEEIPEEELSLED-----VQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRA 996

                          730
                   ....*....|....*.
gi 133903949   897 RLKEKmRKELEKLNEQ 912
Cdd:TIGR02169  997 KLEEE-RKAILERIEE 1011
PTZ00121 PTZ00121
MAEBL; Provisional
 268-771 9.41e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 70.94  E-value: 9.41e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  268 ANDLDRQLTEFTRCATLMRKAIRHAEQKNLDQKEQMKREKDDVLDETLRQLNSvtENYMKSEEKANERQRDLKRKEDECR 347
Cdd:PTZ00121 1433 ADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKA--DEAKKKAEEAKKKADEAKKAAEAKK 1510

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  348 KLRE-QNDELSDILEQLSKMAHEMAGGRGRNETPMDVARKMRKLLTTKNGEIDESREAAKQAEKERDRAKKDLEKEEKRR 426
Cdd:PTZ00121 1511 KADEaKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAE 1590

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  427 KDDREAERKRSSVYSQREHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQFIEELMIRHREELKE 506
Cdd:PTZ00121 1591 EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA 1670

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  507 REDSHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETER 586
Cdd:PTZ00121 1671 EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAK 1750

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  587 EQADQRD----LEIAECRAKLDEMAEKEAELRKELAEfQAIITAMEGEGKL-----NQEQFLESKNE----LNTLTDQIE 653
Cdd:PTZ00121 1751 KDEEEKKkiahLKKEEEKKAEEIRKEKEAVIEEELDE-EDEKRRMEVDKKIkdifdNFANIIEGGKEgnlvINDSKEMED 1829

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  654 SLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATY--EEANGEIDILKAELTRLHEQVNERTRQISEANEKYdd 731
Cdd:PTZ00121 1830 SAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFnkEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNM-- 1907

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|
gi 133903949  732 aARKNDALLEDvatwqekyeqlKMELEEMNRRGQEKEREE 771
Cdd:PTZ00121 1908 -AGKNNDIIDD-----------KLDKDEYIKRDAEETREE 1935
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 402-1191 1.75e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 69.76  E-value: 1.75e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   402 REAAKQAEKERDRAKKDLEKeekRRKDDREAERKRSSVYSQREHDLKKLDDEL---RKASEKIRNLEEQreSQEKLTISV 478
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQR---RLNESNELHEKQKFYLRQSVIDLQTKLQEMqmeRDAMADIRRRESQ--SQEDLRNQL 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   479 QNSLNE--AHRQHKQFIEELMIRHREELKEREDSHEEALRskdtEERSRF-EKERSEREKIRRESDELRETQRSLKGDVA 555
Cdd:pfam15921  148 QNTVHEleAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQ----EIRSILvDFEEASGKKIYEHDSMSTMHFRSLGSAIS 223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   556 AMKTDLDDKTLRL--------DMLETERDELKKKLETEREQADQR-DLEIAECRAKLDEMAEKEAELRKELAEFQAIITA 626
Cdd:pfam15921  224 KILRELDTEISYLkgrifpveDQLEALKSESQNKIELLLQQHQDRiEQLISEHEVEITGLTEKASSARSQANSIQSQLEI 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   627 MEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEE-IRNLMATLQEKEVHIQNVRTSSHQLTatyEEANGEIDILK 705
Cdd:pfam15921  304 IQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDkIEELEKQLVLANSELTEARTERDQFS---QESGNLDDQLQ 380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   706 AELTRLHEQVNERTRQiSEANEKYDDAARKNDALLEdvatwqekyeQLKMELEEmnrRGQEKEREEADLRALLDDLRGNF 785
Cdd:pfam15921  381 KLLADLHKREKELSLE-KEQNKRLWDRDTGNSITID----------HLRRELDD---RNMEVQRLEALLKAMKSECQGQM 446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   786 DKLTNELKQKGVTVdslnEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEKDRQgvenfgkeCEA 865
Cdd:pfam15921  447 ERQMAAIQGKNESL----EKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERA--------IEA 514

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   866 RMNELTKIH---EMLMEEHDQLKV--DHL-HTEEEVERLKEKM----------RKELEKLNE---QNDGDRAEWSNERNR 926
Cdd:pfam15921  515 TNAEITKLRsrvDLKLQELQHLKNegDHLrNVQTECEALKLQMaekdkvieilRQQIENMTQlvgQHGRTAGAMQVEKAQ 594

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   927 LESSKNEAVTELQERvqkleDVVKEKEDKEIalrrdledsheksRDLDDKLRKMELtdeekeedrkkeqktlneERMKLM 1006
Cdd:pfam15921  595 LEKEINDRRLELQEF-----KILKDKKDAKI-------------RELEARVSDLEL------------------EKVKLV 638

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1007 EQKEEAMLVATKHATTIDQQTRRISVLEGDVEKLTAGIAERESSI----NALESNTMELISKLETTEAELEKLKDELAVM 1082
Cdd:pfam15921  639 NAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFrnksEEMETTTNKLKMQLKSAQSELEQTRNTLKSM 718

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1083 LKQNSELKNGKEGLSEKWNEERKKIQDLADQLREANKVVHNMRMKNVNLEEKKNELDQNVTDLTNK----------VRQL 1152
Cdd:pfam15921  719 EGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEknkmagelevLRSQ 798

                          810       820       830
                   ....*....|....*....|....*....|....*....
gi 133903949  1153 EIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNEQFRL 1191
Cdd:pfam15921  799 ERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRL 837
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 287-821 1.95e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.58  E-value: 1.95e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  287 KAIRHAEQKNLDQKEQMKREKDDVLDETLRQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQLSKM 366
Cdd:COG1196   245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEE 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  367 AHEMAggrgrnetpmDVARKMRKLLTTKNGEIDESREAAKQAEKERDRAKKDLEKEEKRRKDDREAERKRSSVYSQREHD 446
Cdd:COG1196   325 LAELE----------EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  447 LKKLDDELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQFIEELmiRHREELKEREDSHEEALRSKDTEERSRF 526
Cdd:COG1196   395 AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEAL--EEAAEEEAELEEEEEALLELLAELLEEA 472

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  527 EKERSEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAE---CRAKL 603
Cdd:COG1196   473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALaaaLQNIV 552

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  604 DEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQE-------K 676
Cdd:COG1196   553 VEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGrtlvaarL 632

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  677 EVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVATWQEKYEQLKME 756
Cdd:COG1196   633 EAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEA 712

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 133903949  757 LEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERK 821
Cdd:COG1196   713 EEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIE 777
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 287-1163 2.33e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 69.23  E-value: 2.33e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   287 KAIRHAEQKNLDQKEQMKREKDDVLDETLRQLNSvtenyMKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQLSKM 366
Cdd:pfam02463  168 KRKKKEALKKLIEETENLAELIIDLEELKLQELK-----LKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLL 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   367 AHEMAGGRGRNETPMDVARKMRKLLTTKNGEIDESREAAKQAEKERDRAKKDLEKEEKRRKDDREAERKRSSVYSQREHD 446
Cdd:pfam02463  243 QELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   447 LKKLDDELRKASEKIRNLEEQRESQEKLTISVQN------SLNEAHRQHKQFIEELMIRHREELKEREDSHEEALRSKDT 520
Cdd:pfam02463  323 KKKAEKELKKEKEEIEELEKELKELEIKREAEEEeeeeleKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSE 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   521 EERSRfekeRSEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAECR 600
Cdd:pfam02463  403 EEKEA----QLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   601 AKLDEMAEKEAELRKELAEFQAIITAMEGEGKLNqeqFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHI 680
Cdd:pfam02463  479 LVKLQEQLELLLSRQKLEERSQKESKARSGLKVL---LALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSA 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   681 QnVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEM 760
Cdd:pfam02463  556 T-ADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTEL 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   761 NRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKE 840
Cdd:pfam02463  635 TKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKK 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   841 EYEVKLQLAEKDRQGVENFGKECEARMNELTKIHEmlmeehdqlkvdhlhtEEEVERLKEKMRKELEKLNEQNDGDRAEW 920
Cdd:pfam02463  715 LKLEAEELLADRVQEAQDKINEELKLLKQKIDEEE----------------EEEEKSRLKKEEKEEEKSELSLKEKELAE 778

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   921 SNERNRLESSKNEAVTELQERVQKLEDVVKEKEDKEIALRRDLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNE 1000
Cdd:pfam02463  779 EREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELER 858

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1001 ERMKLMEQKEEAMLVATKHATTIDQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAELEKLKDELA 1080
Cdd:pfam02463  859 LEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPE 938

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1081 VMLKQNselKNGKEGLSEKWNEERKKIQDLADQLREANKVVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKA 1160
Cdd:pfam02463  939 ELLLEE---ADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEET 1015


                   ...
gi 133903949  1161 AKN 1163
Cdd:pfam02463 1016 CQR 1018
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
295-859 4.77e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 68.17  E-value: 4.77e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  295 KNLDQKEQMKREKDDVLDETLRQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQLSKMAHEMAggr 374
Cdd:PRK03918  165 KNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIE--- 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  375 grnetpmdvarKMRKLLTTKNGEIDESREAAKQAEKERDRAKKDLEKEEKRRKDDREAERKRSSvYSQREHDLKKLDDEL 454
Cdd:PRK03918  242 -----------ELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEE-YIKLSEFYEEYLDEL 309

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  455 RKASEKIRNLEEQRESQEKLtISVQNSLNEAHRQHKQFIEELMiRHREELKEREDSHEEALRSKDTEERSRFEKERSERE 534
Cdd:PRK03918  310 REIEKRLSRLEEEINGIEER-IKELEEKEERLEELKKKLKELE-KRLEELEERHELYEEAKAKKEELERLKKRLTGLTPE 387

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  535 KIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKL------------ETEREQADQRDLEIAECRAK 602
Cdd:PRK03918  388 KLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKgkcpvcgrelteEHRKELLEEYTAELKRIEKE 467

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  603 LDEMAEKEAELRKELAEFQAIITAMEGEGKLNQ--EQFLESKNELNTL--------TDQIESLNSEVENKNEEIRNLMAT 672
Cdd:PRK03918  468 LKEIEEKERKLRKELRELEKVLKKESELIKLKElaEQLKELEEKLKKYnleelekkAEEYEKLKEKLIKLKGEIKSLKKE 547

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  673 LQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLEDvatwQEKYEQ 752
Cdd:PRK03918  548 LEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELERE----EKELKK 623

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  753 LKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTvdSLNEEISSLKEQLNKSEKERKEELLRMEELeq 832
Cdd:PRK03918  624 LEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYL--ELSRELAGLRAELEELEKRREEIKKTLEKL-- 699

                         570       580
                  ....*....|....*....|....*..
gi 133903949  833 KNEAEMKEEYEVKLQLAEKDRQGVENF 859
Cdd:PRK03918  700 KEELEEREKAKKELEKLEKALERVEEL 726
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 602-1239 5.23e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 67.74  E-value: 5.23e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   602 KLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQE------ 675
Cdd:TIGR04523   34 EEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKinseik 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   676 -KEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVATWQEKYEQLK 754
Cdd:TIGR04523  114 nDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIK 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   755 MELEEMNRRG---QEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKErkeellrmeele 831
Cdd:TIGR04523  194 NKLLKLELLLsnlKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDE------------ 261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   832 QKNEAEMKEEYEVKLQLAEKDRQGVENFGKECEARMNELTKIHEMlmEEHDQLKVDHLHTEEEVERLKEKMRKELEKLNE 911
Cdd:TIGR04523  262 QNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQ--DWNKELKSELKNQEKKLEEIQNQISQNNKIISQ 339

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   912 QNDgDRAEWSNERNRLESSKNEAVTELQERVQKLEDVVKEKEDKeialRRDLEDSHEKSRDLDDKLRKMEltdeEKEEDR 991
Cdd:TIGR04523  340 LNE-QISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSY----KQEIKNLESQINDLESKIQNQE----KLNQQK 410

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   992 KKEQKTLNEERMKLMEQKEEAMLVATKHATTIDQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAE 1071
Cdd:TIGR04523  411 DEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKE 490

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1072 LEKLKDELAVMLKQNSELKNGKEGLSEKWNEERKKIQDLADQLREANKVVHNM---------RMKNVNLEEKKNELDQNV 1142
Cdd:TIGR04523  491 LKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLedelnkddfELKKENLEKEIDEKNKEI 570

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1143 TDLTNKVRQLEiqlmdkaAKNEVSGDLLRKMEHDAQSMLKQAQNEQFRLTDLEKVRKALQDENQRLVNDLATVKAAFEvK 1222
Cdd:TIGR04523  571 EELKQTQKSLK-------KKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKN-K 642

                          650
                   ....*....|....*..
gi 133903949  1223 RETSKSAISDILDKYRS 1239
Cdd:TIGR04523  643 LKQEVKQIKETIKEIRN 659
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1372-1855 1.64e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.50  E-value: 1.64e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1372 LRFLKERIEQLEADNADLSDALEKAKDELRQRNEKLADRQMVIERVERQLVHITEERNTIENRMTSQRQMYLTNEESSRS 1451
Cdd:COG1196   290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1452 REHEIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDALESKEKATGLVGVQDSKHRDLEEQLDRANRERELAIG 1531
Cdd:COG1196   370 AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1532 KQRRTLAENENLFRKLEQLEKEREQLMREITDERRLNERNRTSLEELRVSERTWKSAMTTAKKPAEEQE-----RAVQEQ 1606
Cdd:COG1196   450 EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGlrglaGAVAVL 529

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1607 RRWEESnhEMTNRNTALTKECDRLRVE----MRDQLNRMNGINLRSVDFERKNEELSSKLIVMQNTVTAMKKFEEEWKRL 1682
Cdd:COG1196   530 IGVEAA--YEAALEAALAAALQNIVVEddevAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASD 607

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1683 EAEMRAELKILRKEKLMQTAEIEDLKRKSFRSDTEKKEIEGIRVRLEREISALKRHVDALEEEKGKTEKAVRETMNERRA 1762
Cdd:COG1196   608 LREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAER 687

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1763 IDKSLASMERENQQLYRNCAQLQAQIQNLERDAGNRSVTKLAKEHSLLEARIAALIEEKRQLQSMLDQKDANYShkRKLL 1842
Cdd:COG1196   688 LAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD--LEEL 765

                         490
                  ....*....|...
gi 133903949 1843 ESQIQLLREQLEA 1855
Cdd:COG1196   766 ERELERLEREIEA 778
PTZ00121 PTZ00121
MAEBL; Provisional
 783-1626 3.07e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 65.93  E-value: 3.07e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  783 GNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEmkEEYEVKLQLAEKDRqgvenfgKE 862
Cdd:PTZ00121 1036 GNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRAD--EATEEAFGKAEEAK-------KT 1106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  863 CEARMNELTKIHEMLMEEHDQLKVDHLHTEEEVERLKEKMRKELEKLNE-QNDGDRAEWSNERNRLESSKNEAVTELQER 941
Cdd:PTZ00121 1107 ETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEiARKAEDARKAEEARKAEDAKKAEAARKAEE 1186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  942 VQKLEDVVKEKEDKEIALRRDLEDsheksrdlddkLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEEamlvatkhat 1021
Cdd:PTZ00121 1187 VRKAEELRKAEDARKAEAARKAEE-----------ERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKA---------- 1245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1022 tidQQTRRISVLEGDVEKLTAGIAERESSINALESNTMElisklETTEAELEKLKDELavmlKQNSELKNGKEglSEKWN 1101
Cdd:PTZ00121 1246 ---EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKAD-----ELKKAEEKKKADEA----KKAEEKKKADE--AKKKA 1311

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1102 EERKKIQDLADQLREANKVVHNMRMKnvnLEEKKNELDQNVTDLTNKVRQLEiqlmdkAAKNEVSGDLLRKMEHDAQS-M 1180
Cdd:PTZ00121 1312 EEAKKADEAKKKAEEAKKKADAAKKK---AEEAKKAAEAAKAEAEAAADEAE------AAEEKAEAAEKKKEEAKKKAdA 1382

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1181 LKQAQNEQFRLTDLEKVRKALQDENQRLVNDLATVKAAFEVKRETSKSAISDILDKyrSAEEKANKGELDNQRLRSDLAt 1260
Cdd:PTZ00121 1383 AKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKK--KAEEAKKADEAKKKAEEAKKA- 1459

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1261 vtlklerQELKAKDSDNRLRDSQKRFEEVQSKLANLQKSAVESLQNPMSSNSRQNRSIYVDIPRAASsiglnENSDEVPL 1340
Cdd:PTZ00121 1460 -------EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAE-----EAKKADEA 1527

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1341 RSSPSVRFADSSQNMQRAVDSMDVSSSvgvtlrflkerieqleadnADLSDALEKAKDELRQRNEKlaDRQMVIERVErq 1420
Cdd:PTZ00121 1528 KKAEEAKKADEAKKAEEKKKADELKKA-------------------EELKKAEEKKKAEEAKKAEE--DKNMALRKAE-- 1584

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1421 lvhitEERNTIENRMtsQRQMYLTNEESSRSREHEIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDALESKEK 1500
Cdd:PTZ00121 1585 -----EAKKAEEARI--EEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEE 1657

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1501 ATGLVGVQDSKHRDLEEQLDRANRERELAIGKQRRTLAENENLFRKLEQLEKEREQLMREITDERRLNERNRTSLEELRV 1580
Cdd:PTZ00121 1658 ENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKK 1737

                         810       820       830       840
                  ....*....|....*....|....*....|....*....|....*.
gi 133903949 1581 SERTWKSAMTTAKKPAEEQERAVQEQRRWEESNHEMTNRNTALTKE 1626
Cdd:PTZ00121 1738 EAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE 1783
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1453-1878 1.09e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.80  E-value: 1.09e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1453 EHEIRSMKARISTLELHLREKESKLAHLRKEievlhgqlhdalesKEKAtglvgvqdSKHRDLEEQLDRanRERELAIGK 1532
Cdd:COG1196   178 ERKLEATEENLERLEDILGELERQLEPLERQ--------------AEKA--------ERYRELKEELKE--LEAELLLLK 233

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1533 QRRTLAENENLFRKLEQLEKEREQLMREITDERRLNERNRTSLEELR--VSERTWKSAMTTAKKPAEEQERAVQEQRRwe 1610
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELEleLEEAQAEEYELLAELARLEQDIARLEERR-- 311

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1611 esnhemtnrnTALTKECDRLRVEMRDQlnrmnginlrsvdfERKNEELSSKLIVMQNTVTAMKKFEEEWKRLEAEMRAEL 1690
Cdd:COG1196   312 ----------RELEERLEELEEELAEL--------------EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1691 KILRKEKLMQTAEIEDLKRKSFRSDTEKKEIEGIRVRLEREISALKRHVDALEEEKGKTEKAVRETMNERRAIDKSLASM 1770
Cdd:COG1196   368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1771 ERENQQLYRNCAQLQAQIQNLERDAgnrsvTKLAKEHSLLEARIAALIEEKRQLQSMLDQKDANYSHKRKLLESQIQLLR 1850
Cdd:COG1196   448 AEEEAELEEEEEALLELLAELLEEA-----ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGL 522

                         410       420
                  ....*....|....*....|....*...
gi 133903949 1851 EQLEAERRKRTKGVVATGPTVSRRGVQH 1878
Cdd:COG1196   523 AGAVAVLIGVEAAYEAALEAALAAALQN 550
PTZ00121 PTZ00121
MAEBL; Provisional
 695-1321 3.52e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.47  E-value: 3.52e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  695 EEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDAARKNDAllEDVATWQEKYEQLKMELEEMNRrgQEKEREEADL 774
Cdd:PTZ00121 1179 EAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAED--AKKAEAVKKAEEAKKDAEEAKK--AEEERNNEEI 1254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  775 RALLDDLRGNFDKLTNELK--QKGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEKD 852
Cdd:PTZ00121 1255 RKFEEARMAHFARRQAAIKaeEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAA 1334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  853 RQGVENFGKECEARMNELTKIHEMLMEEHDQLKVDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRLESSKN 932
Cdd:PTZ00121 1335 KKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAA 1414

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  933 EAVTELQERVQKLEDVVKEKEDKEIAlrrdledshEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEEA 1012
Cdd:PTZ00121 1415 AAKKKADEAKKKAEEKKKADEAKKKA---------EEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKA 1485

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1013 mlvatkhattidqqtrrisvlegdvEKLTAGIAERESSINALESNTMELISKLETTEAELEKLKDELavmlKQNSELKNG 1092
Cdd:PTZ00121 1486 -------------------------DEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEA----KKAEEAKKA 1536

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1093 KEGlseKWNEERKKiqdlADQLREANKVVHNMRMKNVNlEEKKNELDQNVTdltnkVRQLEIQLMDKAAKNEVSGDLLRK 1172
Cdd:PTZ00121 1537 DEA---KKAEEKKK----ADELKKAEELKKAEEKKKAE-EAKKAEEDKNMA-----LRKAEEAKKAEEARIEEVMKLYEE 1603

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1173 MEHDAQSMLKQAQNEQFRLTDLEKVRKALQDENQRLVNDLATVKAAFEVKRETSKSAISDILDKYRSAEEKANKGELDNQ 1252
Cdd:PTZ00121 1604 EKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKA 1683

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 133903949 1253 RLRSDLATVTLKLERQELKAKDSDNRLRDSQKRFEEVQSKLANLQKSAVESLQNPMSSNSRQNRSIYVD 1321
Cdd:PTZ00121 1684 EEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD 1752
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 576-1298 3.57e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.01  E-value: 3.57e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   576 DELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKE---LAEFQAIITamegegKLNQEQFLESKNELNTLTDQI 652
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRErekAERYQALLK------EKREYEGYELLKEKEALERQK 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   653 ESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEE-ANGEIDILKAELTRLHEQVNERTRQISEANEKYDD 731
Cdd:TIGR02169  240 EAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDlGEEEQLRVKEKIGELEAEIASLERSIAEKERELED 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   732 AARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKE 811
Cdd:TIGR02169  320 AEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKR 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   812 QLNKSEKERKEELLRMEELEQKnEAEMKEEYEVKLQLAEKDRQGVENFGKECEARMNELTKIHEMLMEEHDQLKVDHLHT 891
Cdd:TIGR02169  400 EINELKRELDRLQEELQRLSEE-LADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEY 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   892 EEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRLESSKNE-----AVTEL---QERVQK---------LEDVVKEKED 954
Cdd:TIGR02169  479 DRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIqgvhgTVAQLgsvGERYATaievaagnrLNNVVVEDDA 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   955 ---KEIALRRDledsHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEEAMLVA---TKHATTIDQQTR 1028
Cdd:TIGR02169  559 vakEAIELLKR----RKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVfgdTLVVEDIEAARR 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1029 -----RISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEE 1103
Cdd:TIGR02169  635 lmgkyRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDA 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1104 RKKIQDLADQLREANKVVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKME-HDAQSMLK 1182
Cdd:TIGR02169  715 SRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEaRLSHSRIP 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1183 QAQNE-QFRLTDLEKVRKALQDENQRLvNDLATVKAAFEVKRETSKSAISDILDKyrsaeEKANKGELDNqrLRSDLATV 1261
Cdd:TIGR02169  795 EIQAElSKLEEEVSRIEARLREIEQKL-NRLTLEKEYLEKEIQELQEQRIDLKEQ-----IKSIEKEIEN--LNGKKEEL 866

                          730       740       750
                   ....*....|....*....|....*....|....*..
gi 133903949  1262 TLKLERQELKAKDSDNRLRDSQKRFEEVQSKLANLQK 1298
Cdd:TIGR02169  867 EEELEELEAALRDLESRLGDLKKERDELEAQLRELER 903
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1061-1611 3.73e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 3.73e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1061 LISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERKKIQDLADQLREANKVVHNMRMKNVNLEEKKNELDQ 1140
Cdd:COG1196   230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEE 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1141 NVTDLTNKVRQLEIQLMDKAAKNEvsgdLLRKMEHDAQSMLKQAQNEQFRLTDLEKVRKALQDENQRLVNDLATVKAAFE 1220
Cdd:COG1196   310 RRRELEERLEELEEELAELEEELE----ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1221 VKRETSKSAISDILDKYRSAEEKANKGELDNQRLRSDLATVTLKLERQELKAKDSDNRLRDSQKRFEEVQSKLANLQKSA 1300
Cdd:COG1196   386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1301 VESLQNpMSSNSRQNRSIYVDIPRAASSIGLNENSDEVPLRSSPSVRFADSSQNMQRAVDSMDVSSSVGVtlrflKERIE 1380
Cdd:COG1196   466 AELLEE-AALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA-----AYEAA 539

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1381 QLEADNADLSDALEKAKDELRQRNEKLADRQmvIERVERQLVHITEERNTIENRMTSQRQMYLTNEESSRSREHEIRSmK 1460
Cdd:COG1196   540 LEAALAAALQNIVVEDDEVAAAAIEYLKAAK--AGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARY-Y 616

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1461 ARISTLELHLREKESKLAHLRKEIEVLHGQLHDALESKEKATGLVGVQDSKHRDLEEQLDRANRERELAIGKQRRTLAEN 1540
Cdd:COG1196   617 VLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 133903949 1541 ENLFRKLEQLEKEREQLMREITDERRLNERNRTSLEELRVSERTWKSAMTTAKKPAEEQERAVQEQRRWEE 1611
Cdd:COG1196   697 EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1363-1755 4.15e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.01  E-value: 4.15e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1363 DVSSSVGVTLRFLKERIEQLeADNADLSDALEKAKDELRQRNEKLADRQMVIERVERQLVHITEERNTIENRMTSQRQM- 1441
Cdd:TIGR02169  143 DVTDFISMSPVERRKIIDEI-AGVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKr 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1442 ----------YLTNEESSR-------SREHEIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDALESK-EKATG 1503
Cdd:TIGR02169  222 eyegyellkeKEALERQKEaierqlaSLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKiGELEA 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1504 LVGVQDSKHRDLEEQLDRANRERELAIGKQRRTLAENENLFRKLEQLEKEREQLMREITDERRLNERNRTSLEELRVSER 1583
Cdd:TIGR02169  302 EIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFA 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1584 TWKsamttakkpaeeqERAVQEQRRWEESNHEMTNRNTALTKECDRLRvemrdqlnrmnginLRSVDFERKNEELSSKLi 1663
Cdd:TIGR02169  382 ETR-------------DELKDYREKLEKLKREINELKRELDRLQEELQ--------------RLSEELADLNAAIAGIE- 433

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1664 vmqntvTAMKKFEEEWKRLEAEMRAElkilrKEKLMQTAEIEDLKRKSFRSDTEKKEiegirvRLEREISALKRHVDALE 1743
Cdd:TIGR02169  434 ------AKINELEEEKEDKALEIKKQ-----EWKLEQLAADLSKYEQELYDLKEEYD------RVEKELSKLQRELAEAE 496

                          410
                   ....*....|..
gi 133903949  1744 EEKGKTEKAVRE 1755
Cdd:TIGR02169  497 AQARASEERVRG 508
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1375-1817 7.04e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 7.04e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1375 LKERIEQLEADNADLSDALEKAKDELRQRNEKLADRQMVIERVERQLVHITEERNTIENRMTSQRQMYLTNEESSRSREH 1454
Cdd:COG1196   321 LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1455 EIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDALESKEKATGLVGVQDSKHRDLEEQLDRANRERELAIGKQR 1534
Cdd:COG1196   401 QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1535 RTLAENENLFRKLEQLEKEREQLMREITDERRLNERNRTSLEELRVSERTWKSAMTTAKKPAEEQERAVQEQRRWEES-- 1612
Cdd:COG1196   481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVaa 560

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1613 ---NHEMTNRNTALTKE-CDRLRVEMRDQLNRMNGINLRSVDF-ERKNEELSSKLIVMQNTVTAMKKFEEEWKRLEAEMR 1687
Cdd:COG1196   561 aaiEYLKAAKAGRATFLpLDKIRARAALAAALARGAIGAAVDLvASDLREADARYYVLGDTLLGRTLVAARLEAALRRAV 640

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1688 AELKILRKEKLMQTAEIEDLKRKSFRSDTEKKEIEGIRVRLEREISALKRHVDALEEEKGKTEKAVRETMNERRAIDKSL 1767
Cdd:COG1196   641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEE 720

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 133903949 1768 ASMERENQQLY---RNCAQLQAQIQNLERDAG------NRSVTKLAKEHSLLEARIAAL 1817
Cdd:COG1196   721 LEEEALEEQLEaerEELLEELLEEEELLEEEAleelpePPDLEELERELERLEREIEAL 779
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 577-782 1.46e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.01  E-value: 1.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  577 ELKKKLETEREQADQrdlEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLN 656
Cdd:COG4942    20 DAAAEAEAELEQLQQ---EIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  657 SEVENKNEEIRNLMATLQEKEVH-----------IQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISEA 725
Cdd:COG4942    97 AELEAQKEELAELLRALYRLGRQpplalllspedFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 133903949  726 NEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLR 782
Cdd:COG4942   177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
645-1208 1.54e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.05  E-value: 1.54e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  645 LNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIqnvrtsshqltATYEEANGEIDILKAELTRLHEQVNErtrqise 724
Cdd:PRK02224  208 LNGLESELAELDEEIERYEEQREQARETRDEADEVL-----------EEHEERREELETLEAEIEDLRETIAE------- 269

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  725 anekyddAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNE 804
Cdd:PRK02224  270 -------TEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNE 342

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  805 EISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEKDRQGVENFGK--ECEARMNELTKIHEMLMEEHD 882
Cdd:PRK02224  343 EAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERfgDAPVDLGNAEDFLEELREERD 422

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  883 QLKVDHLHTEEEVERLKEKMRKELEKLNEqndGDRAEWSNERNrlESSKNEAVTELQERVQKLEDVVKEKEDKEIALRRD 962
Cdd:PRK02224  423 ELREREAELEATLRTARERVEEAEALLEA---GKCPECGQPVE--GSPHVETIEEDRERVEELEAELEDLEEEVEEVEER 497

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  963 LEdSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEEAmlvaTKHATTIDQQTRRISVLEGDVEKLTA 1042
Cdd:PRK02224  498 LE-RAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERA----AELEAEAEEKREAAAEAEEEAEEARE 572

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1043 GIAERESSINALESnTMELISKLETTEAELEKLKDELavmlkqnSELKNGKEGLSEKWNEERKKIQDLADQLREANKVVH 1122
Cdd:PRK02224  573 EVAELNSKLAELKE-RIESLERIRTLLAAIADAEDEI-------ERLREKREALAELNDERRERLAEKRERKRELEAEFD 644

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1123 NMRMKNvnLEEKKNELDQNVTDLTNKVRQLeiqlmdkaaknevsgdllRKMEHDAQSMLKQAQNEQFRLTDLEKVRKALQ 1202
Cdd:PRK02224  645 EARIEE--AREDKERAEEYLEQVEEKLDEL------------------REERDDLQAEIGAVENELEELEELRERREALE 704


                  ....*.
gi 133903949 1203 DENQRL 1208
Cdd:PRK02224  705 NRVEAL 710
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 297-1011 2.53e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 59.31  E-value: 2.53e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   297 LDQKEQMKREKDdvldETLRQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDELSD-----ILEQLSKMAHEMA 371
Cdd:TIGR02169  229 LKEKEALERQKE----AIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeeqlrVKEKIGELEAEIA 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   372 GGRGRNETPMDVARKMRKLLTTKNGEIDESREAAKQAEKERDRAKKDLEKEEKRRKDDREAERKRSSVYSQREHDLKKLD 451
Cdd:TIGR02169  305 SLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETR 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   452 DELRKASEKIRNLEEQRESQEKLTISVQNSLNEAH---RQHKQFIEELMIRHREELKEREDSHEE--ALRSKDTEERSRF 526
Cdd:TIGR02169  385 DELKDYREKLEKLKREINELKRELDRLQEELQRLSeelADLNAAIAGIEAKINELEEEKEDKALEikKQEWKLEQLAADL 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   527 EKERSEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLE---------TEREQADQRDLEIA 597
Cdd:TIGR02169  465 SKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgtvaqlGSVGERYATAIEVA 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   598 ECRA------KLDEMAEKEAELRKELAEFQAI---ITAMEGEGK----LNQEQFLESKNELNTLTDQIESL------NSE 658
Cdd:TIGR02169  545 AGNRlnnvvvEDDAVAKEAIELLKRRKAGRATflpLNKMRDERRdlsiLSEDGVIGFAVDLVEFDPKYEPAfkyvfgDTL 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   659 VENKNEEIRNLMAT---------LQEKEVHIQ--NVRTSSHQLTATYEEA-----NGEIDILKAELTRLHEQVNERTRQI 722
Cdd:TIGR02169  625 VVEDIEAARRLMGKyrmvtlegeLFEKSGAMTggSRAPRGGILFSRSEPAelqrlRERLEGLKRELSSLQSELRRIENRL 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   723 SEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQkgvtvdsL 802
Cdd:TIGR02169  705 DELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHK-------L 777

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   803 NEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEKDRQGVENFGKECEARMNELTKIHEMLMEEHD 882
Cdd:TIGR02169  778 EEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIE 857

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   883 QLKVDHLHTEEEVERLKEKMR---KELEKLNEQNDGDRAEWSNERNRLES------SKNEAVTELQERVQKLEDVVKEKE 953
Cdd:TIGR02169  858 NLNGKKEELEEELEELEAALRdleSRLGDLKKERDELEAQLRELERKIEEleaqieKKRKRLSELKAKLEALEEELSEIE 937

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 133903949   954 DKEIALRR------DLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNE---ERMKLMEQKEE 1011
Cdd:TIGR02169  938 DPKGEDEEipeeelSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDElkeKRAKLEEERKA 1004
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
447-1117 2.92e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.92  E-value: 2.92e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  447 LKKLDDELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQFIEelmirhreelKEREDSHEEALRSKDTEERSRF 526
Cdd:PRK03918  157 LDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEE----------VLREINEISSELPELREELEKL 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  527 EKERSEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLEtEREQADQRDLEIAECRAKLDEM 606
Cdd:PRK03918  227 EKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVK-ELKELKEKAEEYIKLSEFYEEY 305

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  607 AEKEAELRKELAEFQAIITAMEGEgklnqeqfLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTS 686
Cdd:PRK03918  306 LDELREIEKRLSRLEEEINGIEER--------IKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERL 377

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  687 SHQLTA-TYEEANGEIDILKAELTRLHEQVNERTRQISEANEKyddAARKNDALledvatwqEKYEQLKMELEEMNRRGQ 765
Cdd:PRK03918  378 KKRLTGlTPEKLEKELEELEKAKEEIEEEISKITARIGELKKE---IKELKKAI--------EELKKAKGKCPVCGRELT 446

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  766 EKEREEAdlrallddlrgnFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERkeellrmeeleqKNEAEMKEEYEVK 845
Cdd:PRK03918  447 EEHRKEL------------LEEYTAELKRIEKELKEIEEKERKLRKELRELEKVL------------KKESELIKLKELA 502

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  846 LQLAEKDRQGVENFGKECEARMNELtkihEMLMEEHDQLKVDHLHTEEEVERLKEkMRKELEKLNEQNDGDRAEWSNERN 925
Cdd:PRK03918  503 EQLKELEEKLKKYNLEELEKKAEEY----EKLKEKLIKLKGEIKSLKKELEKLEE-LKKKLAELEKKLDELEEELAELLK 577

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  926 RLESSKNEAVTELQERVQKLEDVVKEkedkeialRRDLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKL 1005
Cdd:PRK03918  578 ELEELGFESVEELEERLKELEPFYNE--------YLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKEL 649

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1006 MEQKEEamlvatkhattidqqtrrisVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQ 1085
Cdd:PRK03918  650 EELEKK--------------------YSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKA 709

                         650       660       670
                  ....*....|....*....|....*....|..
gi 133903949 1086 NSELKNGKEGLsEKWNEERKKIQDLADQLREA 1117
Cdd:PRK03918  710 KKELEKLEKAL-ERVEELREKVKKYKALLKER 740
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
410-982 3.37e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.92  E-value: 3.37e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  410 KERDRAKKDLEKEEKRRKDDREAERKRSSVYSQREHDLKKLDDELRKASEKIRNLEEQRESQEKL--TISVQNSLNEAHR 487
Cdd:PRK03918  172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELkeEIEELEKELESLE 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  488 QHKQFIEELmIRHREELKEREDSHEEALRSKdTEERSRFEKERSEREKIRRESDELRETQRSLKgdvaamktdlddktLR 567
Cdd:PRK03918  252 GSKRKLEEK-IRELEERIEELKKEIEELEEK-VKELKELKEKAEEYIKLSEFYEEYLDELREIE--------------KR 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  568 LDMLETERDELKKKLEtereqadqrdlEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEgEGKLNQEQFLESKNELNT 647
Cdd:PRK03918  316 LSRLEEEINGIEERIK-----------ELEEKEERLEELKKKLKELEKRLEELEERHELYE-EAKAKKEELERLKKRLTG 383

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  648 LT-DQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQ--VNERTRQISE 724
Cdd:PRK03918  384 LTpEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKelLEEYTAELKR 463

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  725 anekyddaarkndaLLEDVATWQEKYEQLKMELEEMnRRGQEKEREEADLRALLDDLRGNFDKLTN----ELKQKGVTVD 800
Cdd:PRK03918  464 --------------IEKELKEIEEKERKLRKELREL-EKVLKKESELIKLKELAEQLKELEEKLKKynleELEKKAEEYE 528

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  801 SLNEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEKDRQGVENFgKECEARMNELTKIHEMLME- 879
Cdd:PRK03918  529 KLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESV-EELEERLKELEPFYNEYLEl 607

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  880 -------EHDQLKVDHLHTE-EEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRlesSKNEAVTELQERVQKLEDVVKE 951
Cdd:PRK03918  608 kdaekelEREEKELKKLEEElDKAFEELAETEKRLEELRKELEELEKKYSEEEYE---ELREEYLELSRELAGLRAELEE 684

                         570       580       590
                  ....*....|....*....|....*....|.
gi 133903949  952 KEDKEIALRRDLEDSHEKSRDLDDKLRKMEL 982
Cdd:PRK03918  685 LEKRREEIKKTLEKLKEELEEREKAKKELEK 715
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
337-913 4.32e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 58.39  E-value: 4.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  337 RDLKRKEDECRKLREQNDELSDILEQLSKMAHEMAGGRG----RNETPMDVARKMRKLLTTkngEIDESREAAKQAEKER 412
Cdd:COG4913   235 DDLERAHEALEDAREQIELLEPIRELAERYAAARERLAEleylRAALRLWFAQRRLELLEA---ELEELRAELARLEAEL 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  413 DRAKKDLEKEEKRRkddREAERKRSSVYSQREHDLKK-LDDELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQ 491
Cdd:COG4913   312 ERLEARLDALREEL---DELEAQIRGNGGDRLEQLEReIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAE 388

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  492 FieelmirhrEELKEREDSHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAMktdlddktlrldml 571
Cdd:COG4913   389 A---------AALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLAL-------------- 445

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  572 eteRDELKKKLetereQADQRDLEIAecrAKLDEMAEKEAELR------------------KELAEFQAIITAMEGEGKL 633
Cdd:COG4913   446 ---RDALAEAL-----GLDEAELPFV---GELIEVRPEEERWRgaiervlggfaltllvppEHYAAALRWVNRLHLRGRL 514

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  634 NQEQFLESKNELNTLTDQIESLNSEVENKNEEIRN-LMATLQEKEVHI-----QNVRTSSHQLTA--------TYEEANG 699
Cdd:COG4913   515 VYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAwLEAELGRRFDYVcvdspEELRRHPRAITRagqvkgngTRHEKDD 594

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  700 E----------------IDILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLE---------DVATWQEKYEQLK 754
Cdd:COG4913   595 RrrirsryvlgfdnrakLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRlaeyswdeiDVASAEREIAELE 674

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  755 MELEEM---NRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRM---- 827
Cdd:COG4913   675 AELERLdasSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALleer 754

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  828 --EELEQKNEAEMKEEYEVKLQLAEKDRQGVENfgkECEARMNELTKIHEML--------------MEEHDQLKVDHLHt 891
Cdd:COG4913   755 faAALGDAVERELRENLEERIDALRARLNRAEE---ELERAMRAFNREWPAEtadldadleslpeyLALLDRLEEDGLP- 830

                         650       660
                  ....*....|....*....|..
gi 133903949  892 eeeveRLKEKMRKELEKLNEQN 913
Cdd:COG4913   831 -----EYEERFKELLNENSIEF 847
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1235-1862 6.21e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.14  E-value: 6.21e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1235 DKYRSAEEKANKGELDNQRLRSDLATVTLKLERQELKAKDSDNRLRDSQKRFEEVQSKLANLQKSaVESLQNPMSSNSRQ 1314
Cdd:TIGR02168  239 EELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQ-KQILRERLANLERQ 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1315 NRSIYVDIPRAASSI---------------GLNENSDEVPLRSSpsvRFADSSQNMQRAVDSMDV--------SSSVGVT 1371
Cdd:TIGR02168  318 LEELEAQLEELESKLdelaeelaeleekleELKEELESLEAELE---ELEAELEELESRLEELEEqletlrskVAQLELQ 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1372 LRFLKERIEQLEADNADLSDALEKAKDELRQRNEKL-----ADRQMVIERVERQLVHITEERNTIENRMTSQRQMYLTNE 1446
Cdd:TIGR02168  395 IASLNNEIERLEARLERLEDRRERLQQEIEELLKKLeeaelKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1447 ESSRSREHEIRSMKARISTLELHLREKES------KLAHLRKEIEVLHGQLHDALESKEKATGLVGVqdskhrDLEEQLD 1520
Cdd:TIGR02168  475 QALDAAERELAQLQARLDSLERLQENLEGfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEA------ALGGRLQ 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1521 RANRERELAIGKQRRTLAENENLFRKLEQLEKEREQLMREITDERRLNERNRTSLEELRVSERT----------WKSAMT 1590
Cdd:TIGR02168  549 AVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPklrkalsyllGGVLVV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1591 TAKKPAEEQERAVQEQRRWEESNHEMTNRNTALTKECDRLRVEMRDQLNRMNGINLRSVDFERKNEELSSKLIVMQNTVT 1670
Cdd:TIGR02168  629 DDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELE 708

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1671 AMKKFEEEWKRLEAEMRAELKILRKEKLMQTAEIEDLKRKSFRSDTEKKEIEGIRVRLEREISALKRHVDALEEEKGKTE 1750
Cdd:TIGR02168  709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELE 788

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1751 KAVRETMNERRAIDKSLASMERENQQLYRNCAQLQAQIQNLERDAGN--RSVTKLAKEHSLLEARIAALIEEKRQLQSML 1828
Cdd:TIGR02168  789 AQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAAteRRLEDLEEQIEELSEDIESLAAEIEELEELI 868

                          650       660       670
                   ....*....|....*....|....*....|....
gi 133903949  1829 DQKDANYSHKRKLLESQIQLLREQLEAERRKRTK 1862
Cdd:TIGR02168  869 EELESELEALLNERASLEEALALLRSELEELSEE 902
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 635-821 8.33e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.70  E-value: 8.33e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  635 QEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQ 714
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  715 VNERTRQISE------------------ANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRA 776
Cdd:COG4942    99 LEAQKEELAEllralyrlgrqpplalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 133903949  777 LLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERK 821
Cdd:COG4942   179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE 223
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 403-626 1.00e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.31  E-value: 1.00e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  403 EAAKQAEKERDRAKKDLEKEEKRRKddrEAERKRSSVYSQrehdLKKLDDELRKASEKIRNLEEQRESQEKLTISVQNSL 482
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELA---ALKKEEKALLKQ----LAALERRIAALARRIRALEQELAALEAELAELEKEI 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  483 NEAHRQHKQFIEELMIRHREELKEREDSHEEALRSKDTEERS--RFEKERSEREKIRRESDELRETQRSLKGDVAAMKTD 560
Cdd:COG4942    93 AELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAvrRLQYLKYLAPARREQAEELRADLAELAALRAELEAE 172

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 133903949  561 LDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIITA 626
Cdd:COG4942   173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
398-851 1.81e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 56.31  E-value: 1.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  398 IDESREAAKQAEKERDRAKKDLEKEEKRRKDDREAERKRSSVYSQREHDLKKLDDELRKASEKIRNLEEQRESQEKLtIS 477
Cdd:COG4717    48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKL-LQ 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  478 VQNSLNEAhRQHKQFIEELMIRHrEELKEREDSHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAM 557
Cdd:COG4717   127 LLPLYQEL-EALEAELAELPERL-EELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEEL 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  558 KTDLDDKTLRLDMLETERDELKKKLetEREQADQRDLEIAECRAKLDEMAE----------KEAELRKELAEFQAIITAM 627
Cdd:COG4717   205 QQRLAELEEELEEAQEELEELEEEL--EQLENELEAAALEERLKEARLLLLiaaallallgLGGSLLSLILTIAGVLFLV 282

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  628 EGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQ-EKEVHIQNVRTSSHQLtATYEEANGEIDILKA 706
Cdd:COG4717   283 LGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGlPPDLSPEELLELLDRI-EELQELLREAEELEE 361

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  707 ELtRLHEQVNERTRQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEmnrrgQEKEREEADLRALLDDLRGNFD 786
Cdd:COG4717   362 EL-QLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEE-----LLGELEELLEALDEEELEEELE 435

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 133903949  787 KLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEK 851
Cdd:COG4717   436 ELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALE 500
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 326-619 2.39e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 55.90  E-value: 2.39e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   326 MKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQLSKMAHEMAGGRGRNETPMDVARKMRKLLTTKNGEIDESREAA 405
Cdd:pfam17380  278 VQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEE 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   406 KQAEKERDRAKKDLEKEEKRRKDDR-EAERKRSSVYSQREHDLKKLDDELRKasEKIRNLEEQRESQEKLTISVQNSLNE 484
Cdd:pfam17380  358 RKRELERIRQEEIAMEISRMRELERlQMERQQKNERVRQELEAARKVKILEE--ERQRKIQQQKVEMEQIRAEQEEARQR 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   485 AHRQHKQFIEELMIRHREELKEREDSHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAM-KTDLDD 563
Cdd:pfam17380  436 EVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMiEEERKR 515

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 133903949   564 KTLRLDMLE-------------TERDELKKKLETEREQADQRDLEIAECRAKLDEMaEKEAELRKELAE 619
Cdd:pfam17380  516 KLLEKEMEErqkaiyeeerrreAEEERRKQQEMEERRRIQEQMRKATEERSRLEAM-EREREMMRQIVE 583
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 880-1734 3.53e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.75  E-value: 3.53e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   880 EHDQLKVDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRLESSKNEAVTELQERVQKLEDVVKEKEDKEIAL 959
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   960 RRDLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEEAMLVATKHATTIDQQTRRISVLEGDVEK 1039
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1040 LTAGIAERESSINALESntmELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERKKIQDLADQLREANK 1119
Cdd:pfam02463  326 AEKELKKEKEEIEELEK---ELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSE 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1120 VVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNEQFRLTDLEKVRK 1199
Cdd:pfam02463  403 EEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1200 ALQDENQRLVNDLATVKAAFEVKRETSKSAISDILD-----------KYRSAEEKANKGELDNQRLRSDLATVTLKLERQ 1268
Cdd:pfam02463  483 QEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDgvggriisahgRLGDLGVAVENYKVAISTAVIVEVSATADEVEE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1269 ELKAKDSDNRLRDSQKRFEEVQSKLANLQKSAVESLQNPMSSNSRQNRSI--YVDIPRAASSIGLNENSDEVPLRSSPSV 1346
Cdd:pfam02463  563 RQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATleADEDDKRAKVVEGILKDTELTKLKESAK 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1347 RFADSSQNMQRAVDSMDVSSSVGVTLRFLKERIEQLEADNADLSDALEKAKDELRQRNEKLAD--RQMVIERVERQLVHI 1424
Cdd:pfam02463  643 AKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEqrEKEELKKLKLEAEEL 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1425 TEERNTIENRMTSQRQMYLTNEESSRSREHEIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDALESKEKATGL 1504
Cdd:pfam02463  723 LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1505 VGVQDSKHRDLEEQLDRANRERELAIGKQRRTLAENENLFRKLEQLEKEREQLMREITDERRLNERNRTSLEELRVSERT 1584
Cdd:pfam02463  803 LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQ 882

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1585 WKSAMTTAKKPAEEQERAVQEQR---------RWEESNHEMTNRNTALTKECDRLRVEMRDQLNRMNGINLRSVDFERKN 1655
Cdd:pfam02463  883 KLKDELESKEEKEKEEKKELEEEsqklnlleeKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERN 962

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1656 EELSSKLIVMQNTVTAMKKFEEEWKRLEAEMRAELKIL---RKEKLMQTAEIEDLKRKSFRSDTEKKEIEGIRVRLEREI 1732
Cdd:pfam02463  963 KRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLeeeKKKLIRAIIEETCQRLKEFLELFVSINKGWNKVFFYLEL 1042


                   ..
gi 133903949  1733 SA 1734
Cdd:pfam02463 1043 GG 1044
PRK01156 PRK01156
chromosome segregation protein; Provisional
 293-787 3.94e-07

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 55.29  E-value: 3.94e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  293 EQKNLDQKEQMKREKDDVLDETLRQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQLSKMAHEMAG 372
Cdd:PRK01156  219 EIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYIN 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  373 GRGRNETPMDVARKMRKLLTTKNGEIDESREAAKQAEKERD---RAKKDLEKEEKRRKDDREAERKRSSVYSQREHDLKK 449
Cdd:PRK01156  299 DYFKYKNDIENKKQILSNIDAEINKYHAIIKKLSVLQKDYNdyiKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKK 378

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  450 LDDELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQFIEEL---------MIRHREELKERE------------ 508
Cdd:PRK01156  379 IEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVsslnqriraLRENLDELSRNMemlngqsvcpvc 458

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  509 -----DSHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAamKTDLDDKTLRLDMLETERDELKKKLE 583
Cdd:PRK01156  459 gttlgEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLE--SEEINKSINEYNKIESARADLEDIKI 536

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  584 TEREQADQRD-LEIAECRAKLDEMAEKEAElRKELAEFQAIITAMEGEGklNQEQFLESKNELNTLTDQIESLNSEVENK 662
Cdd:PRK01156  537 KINELKDKHDkYEEIKNRYKSLKLEDLDSK-RTSWLNALAVISLIDIET--NRSRSNEIKKQLNDLESRLQEIEIGFPDD 613

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  663 NEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQV---NERTRQISEANEKYDDAARKNDAL 739
Cdd:PRK01156  614 KSYIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIpdlKEITSRINDIEDNLKKSRKALDDA 693

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....
gi 133903949  740 LEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLR------ALLDDLRGNFDK 787
Cdd:PRK01156  694 KANRARLESTIEILRTRINELSDRINDINETLESMKkikkaiGDLKRLREAFDK 747
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 484-1287 6.65e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 54.67  E-value: 6.65e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   484 EAHRQHKQFIEELMIRHREELKEREDSHEEALRSKDtEERSRFEKERSEREKIRRESDELRETQRSLKgDVAAMKT---D 560
Cdd:TIGR00606  189 ETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRD-QITSKEAQLESSREIVKSYENELDPLKNRLK-EIEHNLSkimK 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   561 LDDKTLRLDMLETERDELKKKLETEREQADQ-------------------RDLEIAECRAKLDEMAEKEAELRKELAEFQ 621
Cdd:TIGR00606  267 LDNEIKALKSRKKQMEKDNSELELKMEKVFQgtdeqlndlyhnhqrtvreKERELVDCQRELEKLNKERRLLNQEKTELL 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   622 AIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSE-------------------VENKNEEIRNLMATLQEKEvhiqn 682
Cdd:TIGR00606  347 VEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFErgpfserqiknfhtlvierQEDEAKTAAQLCADLQSKE----- 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   683 vRTSSHQLTATYEEANGEIDILKAELTRLHEQVNE---RTRQISEANEKYDDAARKNDALLEDVAtwqekyeqlKMELEE 759
Cdd:TIGR00606  422 -RLKQEQADEIRDEKKGLGRTIELKKEILEKKQEElkfVIKELQQLEGSSDRILELDQELRKAER---------ELSKAE 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   760 MNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLrmeeleQKNEAEMK 839
Cdd:TIGR00606  492 KNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSR------HSDELTSL 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   840 EEYEVKLQLAEKDRQGVENFGKECEARMNELTKIHEMLMEEHDQLKVDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAE 919
Cdd:TIGR00606  566 LGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLK 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   920 WSNERNRLESSKNEAVTELQErvQKLEDVVKEKEDKEIALRRDLE---DSHEKSRDLDDKLRkmeltdeekeeDRKKEQK 996
Cdd:TIGR00606  646 EEIEKSSKQRAMLAGATAVYS--QFITQLTDENQSCCPVCQRVFQteaELQEFISDLQSKLR-----------LAPDKLK 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   997 TLNEERMKLMEQKEEAMLVATKHATTIDQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAEL---- 1072
Cdd:TIGR00606  713 STESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLtdvt 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1073 --EKLKDELAVMLKQNSELKNGKEG--LSEKWNEERKKIQDLADQLREANKVVHNMRmknvNLEEKKNELDQNVTDLTNK 1148
Cdd:TIGR00606  793 imERFQMELKDVERKIAQQAAKLQGsdLDRTVQQVNQEKQEKQHELDTVVSKIELNR----KLIQDQQEQIQHLKSKTNE 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1149 VRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNEQFRLTDLEKVRKALQDENQRLVNDLATVKAAFEVKRETSKS 1228
Cdd:TIGR00606  869 LKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKE 948

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1229 AISDILDKYRSAEEKANKGELDNQRLR-SDLATVTLKLERQELKAKDSDNRLRDSQKRFE 1287
Cdd:TIGR00606  949 KVKNIHGYMKDIENKIQDGKDDYLKQKeTELNTVNAQLEECEKHQEKINEDMRLMRQDID 1008
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 541-763 6.86e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.61  E-value: 6.86e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  541 DELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAE- 619
Cdd:COG4942    23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAq 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  620 ---FQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEE 696
Cdd:COG4942   103 keeLAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 133903949  697 angeidiLKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRR 763
Cdd:COG4942   183 -------LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 673-1579 7.74e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 54.67  E-value: 7.74e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   673 LQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDAARKNDAL-LEDVATWQEKYE 751
Cdd:TIGR00606  222 IRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELeLKMEKVFQGTDE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   752 QLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEELE 831
Cdd:TIGR00606  302 QLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDG 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   832 QKNEAEMKEEYEVKLQLAekdRQGVENFGKECEARMNELTKIHEMLMEEHDQLKVDHLHTEEEVERLKEKMRKELEKL-N 910
Cdd:TIGR00606  382 FERGPFSERQIKNFHTLV---IERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELkF 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   911 EQNDGDRAEWSNERNRlesSKNEAVTELQERVQKLED--VVKEKEDKEIALRRDLEDSHEKSRDLDDKLRKM--ELTDEE 986
Cdd:TIGR00606  459 VIKELQQLEGSSDRIL---ELDQELRKAERELSKAEKnsLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLnhHTTTRT 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   987 KEEDRKKEQKTLNEERMKLMEQKEEAMLVATKHATTIDQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELISKLE 1066
Cdd:TIGR00606  536 QMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELE 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1067 TTEAELEKLKDELAVMLKQNSElKNGKEGLSEKWNEERKKIQDLADQLREANKVVHNMRMKNVNLEEKKNELDQNVTDLT 1146
Cdd:TIGR00606  616 SKEEQLSSYEDKLFDVCGSQDE-ESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQ 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1147 NKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNEQFRLTDLEKVRKALQDENQRLVNDLATVKAAFEvkreTS 1226
Cdd:TIGR00606  695 EFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIE----EQ 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1227 KSAISDILDKYRSAEEKANKGELdNQRLRSDLATVTLKLERQELKAKDSDNRLRDSQKRfEEVQSKLANLQKSAVESLQN 1306
Cdd:TIGR00606  771 ETLLGTIMPEEESAKVCLTDVTI-MERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVN-QEKQEKQHELDTVVSKIELN 848

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1307 PMSSNSRQNRSIYVdipraassiglneNSDEVPLRSSPSVRFADSSQNMQRAVDSMDVSSSVGVTLRFLKERIEQLEADN 1386
Cdd:TIGR00606  849 RKLIQDQQEQIQHL-------------KSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLE 915

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1387 ADLSDALEKAKDELRQRNEKLADRQMVIERVERQLVHITEERNTIENRMTSQRQMYLT---------------NEESSRS 1451
Cdd:TIGR00606  916 TFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKqketelntvnaqleeCEKHQEK 995

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1452 REHEIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDALESKEKATGLVGVQDSKHRDLEEQLDRANRERELAIG 1531
Cdd:TIGR00606  996 INEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALG 1075

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*....
gi 133903949  1532 KQRRTLAENENLFRKLEQLE-KEREQLMREITDERRLNERNRTSLEELR 1579
Cdd:TIGR00606 1076 RQKGYEKEIKHFKKELREPQfRDAEEKYREMMIVMRTTELVNKDLDIYY 1124
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 298-764 1.03e-06

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 53.59  E-value: 1.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   298 DQKEQMKREKDDVLDETLRQLNSVTENYMKSEEKANERQRDLKRKEdecRKLREQNDELSDILEQLSKMAHEMAGGRGRN 377
Cdd:pfam05557   16 NEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLE---KREAEAEEALREQAELNRLKKKYLEALNKKL 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   378 ETPMDVARKMRKLLTTKNGEIDESREAAKQAEKERDRakKDLEKEEKRRKDDreAERKRSSVYSQREHDLKKLDDELRKA 457
Cdd:pfam05557   93 NEKESQLADAREVISCLKNELSELRRQIQRAELELQS--TNSELEELQERLD--LLKAKASEAEQLRQNLEKQQSSLAEA 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   458 SEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKqfIEELMIRHREELKEREDSHE--EALRSKDTEERSRFEKERSEREK 535
Cdd:pfam05557  169 EQRIKELEFEIQSQEQDSEIVKNSKSELARIPE--LEKELERLREHNKHLNENIEnkLLLKEEVEDLKRKLEREEKYREE 246

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   536 IRRESDELRETQRSLKGDVA-AMKTDLD-----DKTLRLDMLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAEK 609
Cdd:pfam05557  247 AATLELEKEKLEQELQSWVKlAQDTGLNlrspeDLSRRIEQLQQREIVLKEENSSLTSSARQLEKARRELEQELAQYLKK 326

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   610 EAELRKELAEFQAIITAMegegklnQEQFLESKNELNTLTDQIESLNSEVENKN------EEIRNLMATLQEKEVHIQNV 683
Cdd:pfam05557  327 IEDLNKKLKRHKALVRRL-------QRRVLLLTKERDGYRAILESYDKELTMSNyspqllERIEEAEDMTQKMQAHNEEM 399

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   684 RTSSHQLTATYEEANGEIDILKAELTRLHEQvnERTRQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRR 763
Cdd:pfam05557  400 EAQLSVAEEELGGYKQQAQTLERELQALRQQ--ESLADPSYSKEEVDSLRRKLETLELERQRLREQKNELEMELERRCLQ 477


                   .
gi 133903949   764 G 764
Cdd:pfam05557  478 G 478
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1032-1854 1.05e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.92  E-value: 1.05e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1032 VLEGDVEKLTAGIA-ERESSINALeSNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKwNEERKKIQDL 1110
Cdd:TIGR02169  139 VLQGDVTDFISMSPvERRKIIDEI-AGVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQAL 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1111 ADQLREANKVVHNMRMKNvnLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEhdaqsmlkqaqneqfr 1190
Cdd:TIGR02169  217 LKEKREYEGYELLKEKEA--LERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELN---------------- 278

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1191 ltdlEKVRKALQDENQRLVNDLATVKAafevKRETSKSAISDILDKYRSAEEKANKGELDNQRLRSDLATVTLKLERQEL 1270
Cdd:TIGR02169  279 ----KKIKDLGEEEQLRVKEKIGELEA----EIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERK 350

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1271 KAKDSDNRLRDSQKRFEEVQSKLANLQKSAVESLQNPMSsnsrqnrsiyvdipraassigLNENSDEVPLRSSPSVRFAD 1350
Cdd:TIGR02169  351 RRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKD---------------------YREKLEKLKREINELKRELD 409

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1351 SSQNMQRAVDSmdvsssvgvTLRFLKERIEQLEADNADLSDALEKAKDELRQRNEKLADRQMVIERVERQLVHITEERNT 1430
Cdd:TIGR02169  410 RLQEELQRLSE---------ELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDR 480

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1431 IENRMTSQRQMYLTNEESSRSREHEIRSMKARISTLELHLREKESKLAHLRK-------EIEVLHGQLHDALESKEKATG 1503
Cdd:TIGR02169  481 VEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSvgeryatAIEVAAGNRLNNVVVEDDAVA 560

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1504 LVGVQDSKhrdlEEQLDRAN---------RERELAIGKQRRTLAENENLFRKLEQLEKEREQ------LMREITDERRLN 1568
Cdd:TIGR02169  561 KEAIELLK----RRKAGRATflplnkmrdERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYvfgdtlVVEDIEAARRLM 636

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1569 ERNRTSLEELRVSERTwkSAMTTAkkpAEEQERAVQEQRRWEESNHEMTNRNTALTKECDRLRVEMRDQLNRMNGINLRS 1648
Cdd:TIGR02169  637 GKYRMVTLEGELFEKS--GAMTGG---SRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQEL 711

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1649 VDFERKNEELSSKLivmqntvTAMKKFEEEWKRLEAEMRAELKILRKEKLMQTAEIEDL-KRKSFRSDT---EKKEIEGI 1724
Cdd:TIGR02169  712 SDASRKIGEIEKEI-------EQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELeARIEELEEDlhkLEEALNDL 784

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1725 RVRLERE-ISALKRHVDALEEEKGKTEKAVRETMNE--RRAIDKSLASMERENQQLYRNCAQLQAQIQNLERDAGNRSVT 1801
Cdd:TIGR02169  785 EARLSHSrIPEIQAELSKLEEEVSRIEARLREIEQKlnRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKE 864

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 133903949  1802 KLAKEHSLLEARIAALIEEKRQLQSMLDQKDANYS---HKRKLLESQIQLLREQLE 1854
Cdd:TIGR02169  865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLReleRKIEELEAQIEKKRKRLS 920
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 163-717 1.22e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.79  E-value: 1.22e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  163 ENLDELFAKLKEELFKNNTLEEVNEMLREENDAALAANEHLRVDATNLSRQLQQLQQQQHTESMRFRSENTRYRNQTETQ 242
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  243 HRKLISLwKEFTAVKRQLHELRTTTANDLDRQLTEFTRCATLMRKAIRHAEQKNLDQKEQMKREKDDVLDETLRQLNSVT 322
Cdd:COG1196   315 EERLEEL-EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  323 ENYMKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQLSKMAHEMAGGRGRNETPMDVARKMRKLLTtkngEIDESR 402
Cdd:COG1196   394 AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE----LLAELL 469

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  403 EAAKQAEKERDRAKKDLEKEEKRRKDDREAERKRSSVYSQRehdlkKLDDELRKASEKIRNLEEQRESQEKLTISVQNSL 482
Cdd:COG1196   470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGV-----KAALLLAGLRGLAGAVAVLIGVEAAYEAALEAAL 544

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  483 NEAHRQHKQFIEELMIRHREELKEREDSHEEALRSkDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAMKTDLD 562
Cdd:COG1196   545 AAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPL-DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLL 623

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  563 DKTLRLDMLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESK 642
Cdd:COG1196   624 GRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEE 703

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 133903949  643 NELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNE 717
Cdd:COG1196   704 EEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 950-1775 1.48e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.44  E-value: 1.48e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   950 KEKEDKEIALRRdLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEEAMLVATKHATTIDQQTRR 1029
Cdd:pfam02463  166 RLKRKKKEALKK-LIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQE 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1030 ISVLEGDVEKLTAGIAERESSINALESNTMELISK-LETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERKKIQ 1108
Cdd:pfam02463  245 LLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKeKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1109 DLADQLREANKVVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNEQ 1188
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1189 FRLTDLEKVRKALQDENQRLVNDLATVKAAFEVKRETSKSAISDILDKYRSAEEKANKGELDNQRLRSDLATVTLKLERQ 1268
Cdd:pfam02463  405 KEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1269 ELKAKDSDNRLRDSQKRFEEVQSKLANLQKSAVESLQNPMSSNSRQNRSIYVdipraASSIGLNENSDEVPLRSSPSVRF 1348
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGV-----AVENYKVAISTAVIVEVSATADE 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1349 ADSSQNMQRAV----DSMDVSSSVGVTLRFLKERIEQLEADNADLSDALEKAKDELRQRNEKLADRQMVIERVERQLVHI 1424
Cdd:pfam02463  560 VEERQKLVRALtelpLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKE 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1425 TEERNTIENRMTSQRQMYLTNEESSRSREHEIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDALESKEKATGL 1504
Cdd:pfam02463  640 SAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEA 719

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1505 VGVQDSKhrdLEEQLDRANRERELAIGKQRRTLAENENLFRKLEQLEKEREQLMREITDERRLNERNRTSLEELRVSERT 1584
Cdd:pfam02463  720 EELLADR---VQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKL 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1585 WKSAMTTAKKPAEEQERAVQEQRRWEESNHEMTNRNTALTKECDRLRVEMRDQLNRMNGINlRSVDFERKNEELSSKLIV 1664
Cdd:pfam02463  797 KAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELE-RLEEEITKEELLQELLLK 875

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1665 MQNTVTAMKKFEEEWKRLEAEMRAELKILRKEKLMQtaeIEDLKRKSFRSDTEKKEIEGIRVRLEREISALKRHVDALEE 1744
Cdd:pfam02463  876 EEELEEQKLKDELESKEEKEKEEKKELEEESQKLNL---LEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEE 952

                          810       820       830
                   ....*....|....*....|....*....|.
gi 133903949  1745 EKGKTEKAVRETMNERRAIDKSLASMERENQ 1775
Cdd:pfam02463  953 NNKEEEEERNKRLLLAKEELGKVNLMAIEEF 983
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 294-590 1.52e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 53.20  E-value: 1.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   294 QKNLDQKEQMKREKDDVLDETLRQ--LNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQLSKMAH--- 368
Cdd:pfam17380  303 QEKEEKAREVERRRKLEEAEKARQaeMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEIAMEISRMREler 382

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   369 ---EMAGGRGRNETPMDVARKMRKLLTTKNGEIDESREAAKQAEKERDRAKkdlEKEEKRRKDDREAERKRSSVYSQ-RE 444
Cdd:pfam17380  383 lqmERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEAR---QREVRRLEEERAREMERVRLEEQeRQ 459

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   445 HDLKKL----DDELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQhkqFIEELMIRH--REELKEREDSHEEALRSK 518
Cdd:pfam17380  460 QQVERLrqqeEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQA---MIEEERKRKllEKEMEERQKAIYEEERRR 536

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 133903949   519 DTEERSRFEKERSEREKIRRESDELREtQRSlkgdvaamktdlddktlRLDMLETERDELKKKLETEREQAD 590
Cdd:pfam17380  537 EAEEERRKQQEMEERRRIQEQMRKATE-ERS-----------------RLEAMEREREMMRQIVESEKARAE 590
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
334-815 1.57e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.38  E-value: 1.57e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  334 ERQRD----LKRKEDECRKLREQNDELSDILEQLSKMAHEMAGGRGRNEtpmdvARKMRKLLTTKNGEIDESREAAKQAE 409
Cdd:COG4913   248 REQIEllepIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAE-----LEELRAELARLEAELERLEARLDALR 322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  410 KERDRAKKDLEKEEKRRKDDREAERKRssvysqREHDLKKLDDELRKASEKIRNLEEQRESQEKltisvqnSLNEAHRQH 489
Cdd:COG4913   323 EELDELEAQIRGNGGDRLEQLEREIER------LERELEERERRRARLEALLAALGLPLPASAE-------EFAALRAEA 389

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  490 KQFIEELmirhreelkereDSHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAMKTDL-------- 561
Cdd:COG4913   390 AALLEAL------------EEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALaealglde 457

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  562 --------------DDK-----------TLRLDMLETERDE-----------LKKKLETEREQADQRDLEIAECRAklDE 605
Cdd:COG4913   458 aelpfvgelievrpEEErwrgaiervlgGFALTLLVPPEHYaaalrwvnrlhLRGRLVYERVRTGLPDPERPRLDP--DS 535

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  606 MAEK--------EAELRKELAEFQAIIT---------------------------AMEGEGKLNQEQFLESKNE--LNTL 648
Cdd:COG4913   536 LAGKldfkphpfRAWLEAELGRRFDYVCvdspeelrrhpraitragqvkgngtrhEKDDRRRIRSRYVLGFDNRakLAAL 615

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  649 TDQIESLNSEV---ENKNEEIRNLMATLQEKEVHIQNVRTSS------HQLTATYEEANGEIDILKA---ELTRLHEQVN 716
Cdd:COG4913   616 EAELAELEEELaeaEERLEALEAELDALQERREALQRLAEYSwdeidvASAEREIAELEAELERLDAssdDLAALEEQLE 695

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  717 ERTRQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKg 796
Cdd:COG4913   696 ELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEER- 774

                         570
                  ....*....|....*....
gi 133903949  797 vtVDSLNEEISSLKEQLNK 815
Cdd:COG4913   775 --IDALRARLNRAEEELER 791
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 162-870 1.73e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.44  E-value: 1.73e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   162 EENLDELFAKLKEELFKNNTLEEVNEMLREENDAALAANEHLRVDATNLSRQLQQLQQQQHTESMRFRSENTRYRNQTET 241
Cdd:pfam02463  284 QEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEK 363

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   242 QHRKLISLWKEFTAVKRQLHELRTTTANDLDRQLTEFTRCATLMRKAIRHAEQKNLDQKEQMKREKDDVLDETLRQ---- 317
Cdd:pfam02463  364 LQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIelkq 443

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   318 ----LNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQLSKMAHEMAGGRGRNETPMDVARKMRKLLT- 392
Cdd:pfam02463  444 gkltEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGr 523

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   393 --------TKNGEIDESREAAKQAEKERDRAKKDLEKEEKRRKDDREAERKRSsvYSQREHDLKKLDDELRKASEKIRNL 464
Cdd:pfam02463  524 iisahgrlGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLG--ARKLRLLIPKLKLPLKSIAVLEIDP 601

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   465 EEQRESQEKLTISVQNSLNEAHRQHKQFIEELMIRHREELKEREDSHEEA------------LRSKDTEERSRFEKERSE 532
Cdd:pfam02463  602 ILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGvsleeglaekseVKASLSELTKELLEIQEL 681

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   533 REKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAE 612
Cdd:pfam02463  682 QEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEE 761

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   613 LRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIR-NLMATLQEKEVHIQNVRTSSHQLT 691
Cdd:pfam02463  762 KEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELlEEEQLLIEQEEKIKEEELEELALE 841

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   692 ATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREE 771
Cdd:pfam02463  842 LKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEE 921

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   772 ADLRALLDDLRGNFDK---LTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQL 848
Cdd:pfam02463  922 RIKEEAEILLKYEEEPeelLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLE 1001

                          730       740
                   ....*....|....*....|..
gi 133903949   849 AEKDRQGVENFGKECEARMNEL 870
Cdd:pfam02463 1002 EEKKKLIRAIIEETCQRLKEFL 1023
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
224-603 2.01e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 52.85  E-value: 2.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  224 ESMRFRSENTRYRNQTETQHRKLISLWKEFTAVKRQLHELrTTTANDLDRQLTEFTRcatlMRKAIRHAEQKNLDQKEQM 303
Cdd:COG4717   105 EELEAELEELREELEKLEKLLQLLPLYQELEALEAELAEL-PERLEELEERLEELRE----LEEELEELEAELAELQEEL 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  304 KREKDDVLDETLRQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDELSDILE------------QLSKMAHEMA 371
Cdd:COG4717   180 EELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEaaaleerlkearLLLLIAAALL 259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  372 GGRGRNETPMDVARKMRKLLTT--------------KNGEIDESREAAKQAEKERDRAKKDLEKEEKRRKDDREAERKRS 437
Cdd:COG4717   260 ALLGLGGSLLSLILTIAGVLFLvlgllallflllarEKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEEL 339

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  438 SVYSQREHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQFieelmiRHREELKEREDSHEEALRS 517
Cdd:COG4717   340 LELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQA------EEYQELKEELEELEEQLEE 413

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  518 KDTEERSRFEKErsEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIA 597
Cdd:COG4717   414 LLGELEELLEAL--DEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEE 491


                  ....*.
gi 133903949  598 ECRAKL 603
Cdd:COG4717   492 WAALKL 497
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 478-1307 2.84e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 52.67  E-value: 2.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   478 VQNSLNEAHRQHKQFIEELMI-RHREELKEREDSHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAA 556
Cdd:pfam02463  144 IEIIAMMKPERRLEIEEEAAGsRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEE 223

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   557 MKTDLDDK-----------TLRLDMLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIIT 625
Cdd:pfam02463  224 EYLLYLDYlklneeridllQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELL 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   626 AMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVR----TSSHQLTATYEEANGEI 701
Cdd:pfam02463  304 KLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEklqeKLEQLEEELLAKKKLES 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   702 DILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDL 781
Cdd:pfam02463  384 ERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKD 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   782 RGNFDKLTNELKQKGVTVdslnEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEkDRQGVENFGK 861
Cdd:pfam02463  464 ELELKKSEDLLKETQLVK----LQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAH-GRLGDLGVAV 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   862 ECEARMNELTKIHEMLMEEHDQLKVDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRLESSKNEAVTElqer 941
Cdd:pfam02463  539 ENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLE---- 614

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   942 vqKLEDVVKEKEDKEIALRRDLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEEAMLVATKHAT 1021
Cdd:pfam02463  615 --ADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKE 692

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1022 TIDQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELISKlETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWN 1101
Cdd:pfam02463  693 EILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKIN-EELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSL 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1102 EERKKIQDLADQLREANKVVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKaaKNEVSGDLLRKMEHDAQSML 1181
Cdd:pfam02463  772 KEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEK--IKEEELEELALELKEEQKLE 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1182 KQAQNEQFRLTDLEKVRKALQDENQRLVNDLATVKAAFEVKRETSKSAISDILDKYRSAEEKANKGELDNQRLRSDLATV 1261
Cdd:pfam02463  850 KLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEI 929

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*.
gi 133903949  1262 TLKLERQELKAKDSDNRLRDSQKRFEEVQSKLANLQKSAVESLQNP 1307
Cdd:pfam02463  930 LLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKV 975
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
238-796 7.67e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.22  E-value: 7.67e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  238 QTETQHRKLISLWKEFTAVKRQLHELRTttanDLDRQLTEFTRCATLMRKAIRHAEQKNLDQKEQMKREKD-DVLDETLR 316
Cdd:PRK03918  187 RTENIEELIKEKEKELEEVLREINEISS----ELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSkRKLEEKIR 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  317 QLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQLSKMAHEMaggrGRNETPMDVARKMRKLLTTKNG 396
Cdd:PRK03918  263 ELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRL----SRLEEEINGIEERIKELEEKEE 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  397 EIDESREAAKQAEKERDRAKKDLEKEEKRRKDDREAERKRSSVYSQREHDLKKLDDELRKASE-----------KIRNLE 465
Cdd:PRK03918  339 RLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEeieeeiskitaRIGELK 418

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  466 EQRESQEKLTISVQNS----------LNEAHRqhkqfiEELMIRHREELKEREDSHEEA--LRSKDTEERSRFEKERSER 533
Cdd:PRK03918  419 KEIKELKKAIEELKKAkgkcpvcgreLTEEHR------KELLEEYTAELKRIEKELKEIeeKERKLRKELRELEKVLKKE 492

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  534 EKIRRE---SDELRETQRSLKGdvaAMKTDLDDKTLRLDMLETERDELKKK---LETEREQADQRDLEIAECRAKLDEMA 607
Cdd:PRK03918  493 SELIKLkelAEQLKELEEKLKK---YNLEELEKKAEEYEKLKEKLIKLKGEiksLKKELEKLEELKKKLAELEKKLDELE 569

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  608 EKEAELRKELAEFqAIITAMEGEGKLNQ-EQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTS 686
Cdd:PRK03918  570 EELAELLKELEEL-GFESVEELEERLKElEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKE 648

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  687 SHQLTATYEEAngEIDILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVatwqEKYEQLKMELEEMNRrgqe 766
Cdd:PRK03918  649 LEELEKKYSEE--EYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEK---- 718

                         570       580       590
                  ....*....|....*....|....*....|
gi 133903949  767 kereeadLRALLDDLRGNFDKLTNELKQKG 796
Cdd:PRK03918  719 -------ALERVEELREKVKKYKALLKERA 741
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 566-724 8.45e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.15  E-value: 8.45e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  566 LRLDMLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESKN-- 643
Cdd:COG1579    10 LDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNnk 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  644 ELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQIS 723
Cdd:COG1579    90 EYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELA 169


                  .
gi 133903949  724 E 724
Cdd:COG1579   170 A 170
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 383-982 1.06e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.61  E-value: 1.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   383 VARKMRKLLTTKNGEIDESREAAKQAEKERDRAKKDLE-KEEKRRKDDREAERKRSSVYSQREHDLKKLDDELRKASEKI 461
Cdd:pfam12128  274 IASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSaADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQ 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   462 RNLEEQRESQEKLTISvQNSLNEAHRQHKQFIEELMIRHREELKEREDSHEEALRSKDTEERSRFEKERSE-REKIRRES 540
Cdd:pfam12128  354 SELENLEERLKALTGK-HQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESElREQLEAGK 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   541 DELRETQRSLKGDVAAMKTDLDDKTLRldmleterDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEf 620
Cdd:pfam12128  433 LEFNEEEYRLKSRLGELKLRLNQATAT--------PELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQ- 503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   621 qaiitAMEGEGKLNQeQFLESKNELNTLTDQ--------IESLNSEVENKNEEIRNLMAT--LQEKEVHIQNVRTSSHQL 690
Cdd:pfam12128  504 -----ASEALRQASR-RLEERQSALDELELQlfpqagtlLHFLRKEAPDWEQSIGKVISPelLHRTDLDPEVWDGSVGGE 577

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   691 TATYEeangeidiLKAELTRLheqvnertrQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKERE 770
Cdd:pfam12128  578 LNLYG--------VKLDLKRI---------DVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASRE 640

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   771 EADLRALLDDLRGNFDKLTNELKQKGVTVD-SLNEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKE---EYEVKL 846
Cdd:pfam12128  641 ETFARTALKNARLDLRRLFDEKQSEKDKKNkALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREartEKQAYW 720

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   847 QLAEKDRQGVENFGKECEARMNELTKIHEMLMEEHDQLKVDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAE------- 919
Cdd:pfam12128  721 QVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEvlryfdw 800

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 133903949   920 ----WSNERNRLESSKNEAVTELQERVQKLEDVVKEKEDKEIALRRDLEDSHEKSRDLDDKLRKMEL 982
Cdd:pfam12128  801 yqetWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRC 867
PRK01156 PRK01156
chromosome segregation protein; Provisional
 541-1076 1.13e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 50.67  E-value: 1.13e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  541 DELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRK----- 615
Cdd:PRK01156  186 DYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTaesdl 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  616 --ELAEFQAIITAMEGEGKLNQEQFLESKNELN---TLTDQIESLNSEVENKNEEIRNLMATLQEKEVhIQNVRTSSHQL 690
Cdd:PRK01156  266 smELEKNNYYKELEERHMKIINDPVYKNRNYINdyfKYKNDIENKKQILSNIDAEINKYHAIIKKLSV-LQKDYNDYIKK 344

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  691 TATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKERE 770
Cdd:PRK01156  345 KSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSK 424

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  771 EADLRALLDDLRGNFDKLT---NELKQKGV---------------TVDSLNEEISSLKEQLNKSEKERKeellrmeeleq 832
Cdd:PRK01156  425 VSSLNQRIRALRENLDELSrnmEMLNGQSVcpvcgttlgeeksnhIINHYNEKKSRLEEKIREIEIEVK----------- 493

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  833 KNEAEMKEEYEVKLQLAEKDRQGVENFGKECEARMNELTKIhemlMEEHDQLKVDHLHTEEEVERLKEKMRKELEKLNEQ 912
Cdd:PRK01156  494 DIDEKIVDLKKRKEYLESEEINKSINEYNKIESARADLEDI----KIKINELKDKHDKYEEIKNRYKSLKLEDLDSKRTS 569

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  913 NDGDRAEWSN-ERNRLESSKNEAVTELQERVQKLEDVVKEKEDKEIALRRDLEDSHEKSRDLDDKLRKMEltdeEKEEDR 991
Cdd:PRK01156  570 WLNALAVISLiDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYNEIQ----ENKILI 645

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  992 KKEQKTLNEERMKLMEQKEEAMLVATKHATTIDQQTrRISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAE 1071
Cdd:PRK01156  646 EKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIED-NLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINET 724


                  ....*
gi 133903949 1072 LEKLK 1076
Cdd:PRK01156  725 LESMK 729
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 162-760 1.54e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.32  E-value: 1.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  162 EENLDELFAKLKEELFKNNTLEEVNEMLREENDAALAANEHLRVDATNLSRQLQqlqqqqhtesmrfrsentRYRNQTET 241
Cdd:COG1196   245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA------------------RLEQDIAR 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  242 QHRKLISLWKEFTAVKRQLHELRTTTANDLDRQLTEFTRCATLmrKAIRHAEQKNLDQKEQMKREKDDVLDETLRQLNSV 321
Cdd:COG1196   307 LEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEA--EEELEEAEAELAEAEEALLEAEAELAEAEEELEEL 384

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  322 TENYMKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQLSKmahemaggrgrnetpmdvarkmrkllttkngEIDES 401
Cdd:COG1196   385 AEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEE-------------------------------ALAEL 433

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  402 REAAKQAEKERDRAKKDLEKEEKRRKDDREAERKRSSVYSQREHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQNS 481
Cdd:COG1196   434 EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA 513

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  482 LNEAHRQHKQFIEELMIRHREELKEREDSHEEALRSKDTEERSRFEKERSEREKIRRES----DELRETQRSLKGDVAAM 557
Cdd:COG1196   514 LLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGratfLPLDKIRARAALAAALA 593

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  558 KTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQ 637
Cdd:COG1196   594 RGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAA 673

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  638 FLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEvhiqnvrtsshqltatyEEANGEIDILKAELTRLHEQVNE 717
Cdd:COG1196   674 LLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE-----------------EERLEEELEEEALEEQLEAEREE 736

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|...
gi 133903949  718 RTRQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEM 760
Cdd:COG1196   737 LLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 593-853 1.58e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 49.44  E-value: 1.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  593 DLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMAT 672
Cdd:COG3883    15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  673 LQEKevhiqnvrtsshQLTATYEEAngeidILKAE-----LTRLheqvnERTRQISEAnekyddaarkNDALLEDVATWQ 747
Cdd:COG3883    95 LYRS------------GGSVSYLDV-----LLGSEsfsdfLDRL-----SALSKIADA----------DADLLEELKADK 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  748 EKYEQLKMELEEmnrrgqekerEEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRM 827
Cdd:COG3883   143 AELEAKKAELEA----------KLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAA 212

                         250       260
                  ....*....|....*....|....*.
gi 133903949  828 EELEQKNEAEMKEEYEVKLQLAEKDR 853
Cdd:COG3883   213 AAAAAAAAAAAAAAAAAAAAAAAAAA 238
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1515-1848 1.59e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.06  E-value: 1.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1515 LEEQLDRANRERELaigKQRRTLAENENLFRKLEQLEKEREQLMREITDERRLNERNRTSLEELRVSERTWKSAMTTAKK 1594
Cdd:TIGR02168  205 LERQAEKAERYKEL---KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEE 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1595 PAEEQERAVQEQrrweesnhemTNRNTALTKECDRLRVEMRDQLNRMNGINLRSVDFERKNEELSSKLIVMQNTVTAMKK 1674
Cdd:TIGR02168  282 EIEELQKELYAL----------ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1675 FEEEWKRLEAEMRAELKILRKEKLMQTAEIEDLKRKSFRSDTEKKEIEGIRVRLEREISALKRHVDALEEEKGKTEKAVR 1754
Cdd:TIGR02168  352 ELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1755 ETMNERRAIDKSLASMERENQQLYRNCAQLQAQIQNLERDAGNRSVTKLAKEHSLLEARIAAlieekrqLQSMLDQKDAN 1834
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS-------LERLQENLEGF 504

                          330
                   ....*....|....
gi 133903949  1835 YSHKRKLLESQIQL 1848
Cdd:TIGR02168  505 SEGVKALLKNQSGL 518
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1385-1651 1.92e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.91  E-value: 1.92e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1385 DNADLSDALEKAKDELRQRNEKLADRqmvIERVERQLVHITEERNTIEnrmtsQRQMYLTNEESSRSREHEIRSMKARIS 1464
Cdd:COG4913   607 DNRAKLAALEAELAELEEELAEAEER---LEALEAELDALQERREALQ-----RLAEYSWDEIDVASAEREIAELEAELE 678

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1465 tlelHLREKESKLAHLRKEIEVLHGQLHDALESKEKATGLVGVQDSKHRDLEEQLDRANRERELAIGKQRRTLAEN-ENL 1543
Cdd:COG4913   679 ----RLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALlEER 754

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1544 FRKL---EQLEKEREQLMREITDERRLNERNRTSLEELRVS-ERTWKSAMTTAKKPAE------------EQERAVQEQR 1607
Cdd:COG4913   755 FAAAlgdAVERELRENLEERIDALRARLNRAEEELERAMRAfNREWPAETADLDADLEslpeylalldrlEEDGLPEYEE 834

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 133903949 1608 RWEESNHEMTNRN-TALTKECDRLRVEMRDQLNRMNGInLRSVDF 1651
Cdd:COG4913   835 RFKELLNENSIEFvADLLSKLRRAIREIKERIDPLNDS-LKRIPF 878
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 391-1069 2.09e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 49.66  E-value: 2.09e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   391 LTTKNGEIDESREAAKQAEKERDRAKKDLEKEEKRRKDdreaERKRSSVYSQREHDLKKLDDELRKASEKIRNLEEQR-- 468
Cdd:TIGR00606  421 ERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKF----VIKELQQLEGSSDRILELDQELRKAERELSKAEKNSlt 496

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   469 ESQEKLTISVQNSLNEAHRQHKQFIEELMIRHREElKEREDSHEEALRSKDTEERSRFEKERSEREKIRRESD-----EL 543
Cdd:TIGR00606  497 ETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHT-TTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYfpnkkQL 575

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   544 RETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEaELRKELAEFQAI 623
Cdd:TIGR00606  576 EDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESDLE-RLKEEIEKSSKQ 654

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   624 ITAMEGEGKLNQEQFLESKNELNT---LTDQIESLNSEVENKNEEIRNLMAT----LQEKEVHIQNVRTSSHQLTATYEE 696
Cdd:TIGR00606  655 RAMLAGATAVYSQFITQLTDENQSccpVCQRVFQTEAELQEFISDLQSKLRLapdkLKSTESELKKKEKRRDEMLGLAPG 734

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   697 ANGEIDILKAELTRLHEQVNERTRQIS------EANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRR------- 763
Cdd:TIGR00606  735 RQSIIDLKEKEIPELRNKLQKVNRDIQrlkndiEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKiaqqaak 814

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   764 --GQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEE 841
Cdd:TIGR00606  815 lqGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELS 894

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   842 YEVKlQLAEKDRQGVENFGKECEARMNELTKIHEMLMEEHDQLKVDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWS 921
Cdd:TIGR00606  895 TEVQ-SLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLK 973

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   922 NERNRLeSSKNEAVTELQERVQKLEDVVKekedkeiALRRDLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEE 1001
Cdd:TIGR00606  974 QKETEL-NTVNAQLEECEKHQEKINEDMR-------LMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMG 1045

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 133903949  1002 RMKLMEQKEEAMLVATKHATTIDQQTRRISVLEG-DVEKLTAGIAERESSINALESNTMELISKLETTE 1069
Cdd:TIGR00606 1046 QMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGyEKEIKHFKKELREPQFRDAEEKYREMMIVMRTTE 1114
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 290-915 2.74e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.45  E-value: 2.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   290 RHAEQKNLDQKEQMKREKDDVLDETLRQLNSVTENYMKSEEKANER-QRDLKRKEDECRKLRE----QNDELSDILEQL- 363
Cdd:pfam12128  342 AAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQnNRDIAGIKDKLAKIREardrQLAVAEDDLQALe 421

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   364 SKMAHEMAGGRGR-NETPMDVARKMRKLLTTKNGEIDESREAAKQAEKErDRAKKDLEKEEKRRKDDREAERKRSSVYSQ 442
Cdd:pfam12128  422 SELREQLEAGKLEfNEEEYRLKSRLGELKLRLNQATATPELLLQLENFD-ERIERAREEQEAANAEVERLQSELRQARKR 500

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   443 REHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQFIEELMIRhreELKEREDSHEEALRSKDTEE 522
Cdd:pfam12128  501 RDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISP---ELLHRTDLDPEVWDGSVGGE 577

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   523 RSRFekerserekirresdelretqrSLKGDVAAMktDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAECRAK 602
Cdd:pfam12128  578 LNLY----------------------GVKLDLKRI--DVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGE 633

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   603 LDEMAEKEAELRkelaefQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQ- 681
Cdd:pfam12128  634 LEKASREETFAR------TALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKe 707

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   682 NVRTSSHQLTATYEEANGE----IDILKAELTRLHEQVNERTRQISEANeKYDDAARKNDalledvatwQEKYEQLKMEL 757
Cdd:pfam12128  708 QKREARTEKQAYWQVVEGAldaqLALLKAAIAARRSGAKAELKALETWY-KRDLASLGVD---------PDVIAKLKREI 777

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   758 EEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKqkgVTVDSLNEEISSLKEQLNKSEKERKEELLRMEELEQKNEAE 837
Cdd:pfam12128  778 RTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLA---TQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQ 854

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   838 MKE------------EYEVKLQLAEKDRQGVENFGkECEARMNELTKIHEMLMEEHDQlKVDHLHTEEEVER---LKEKM 902
Cdd:pfam12128  855 QVRlsenlrglrcemSKLATLKEDANSEQAQGSIG-ERLAQLEDLKLKRDYLSESVKK-YVEHFKNVIADHSgsgLAETW 932

                          650
                   ....*....|...
gi 133903949   903 RKELEKLNEQNDG 915
Cdd:pfam12128  933 ESLREEDHYQNDK 945
PTZ00121 PTZ00121
MAEBL; Provisional
 1116-1775 2.85e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.37  E-value: 2.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1116 EANKVVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQ--NEQFRLTD 1193
Cdd:PTZ00121 1059 KAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARkaEEARKAED 1138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1194 LEKVRKALQDENQRLVNDLATVKAAFEVKrETSKSAISDILDKYRSAEE--KANKGELDNQRLRSDLATVTLKLERQELK 1271
Cdd:PTZ00121 1139 ARKAEEARKAEDAKRVEIARKAEDARKAE-EARKAEDAKKAEAARKAEEvrKAEELRKAEDARKAEAARKAEEERKAEEA 1217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1272 AKDSDNRLRDSQKRFEEVQSKlANLQKSAVESLQNPMSSNSRQNRSIYVDIPRAASSIGLNENSDEVplRSSPSVRFADS 1351
Cdd:PTZ00121 1218 RKAEDAKKAEAVKKAEEAKKD-AEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADEL--KKAEEKKKADE 1294

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1352 SQNMQ--RAVDSMDVSSSVGVTLRFLKERIEQLE--ADNADLSDALEKAKDELRQRNEKLADRQM--VIERVERQLVHIT 1425
Cdd:PTZ00121 1295 AKKAEekKKADEAKKKAEEAKKADEAKKKAEEAKkkADAAKKKAEEAKKAAEAAKAEAEAAADEAeaAEEKAEAAEKKKE 1374

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1426 EERNTIENRMTSQRQMYLTNEESSRSREHEIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDA---------LE 1496
Cdd:PTZ00121 1375 EAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAkkadeakkkAE 1454

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1497 SKEKATGLVGVQDSKHRDLEEQLDRANRERELAIGKQRRTLAENENLFRKLEQLEKEREQLMR----EITDERRLNERNR 1572
Cdd:PTZ00121 1455 EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKaeeaKKADEAKKAEEAK 1534

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1573 TSLEELRVSERTWKSAMTTAKKPAEEQERAVQEQRRWEESNHEMTNRNTALTKECDRLRVE----MRDQLNRMNGINLRS 1648
Cdd:PTZ00121 1535 KADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEevmkLYEEEKKMKAEEAKK 1614

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1649 VDFERKNEELSSKLIVMQNTVTAMKKFEEEWKRLEAEMRA--ELKILRKEKLMQTAE-----------IEDLKRKS---- 1711
Cdd:PTZ00121 1615 AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKaeEENKIKAAEEAKKAEedkkkaeeakkAEEDEKKAaeal 1694

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 133903949 1712 FRSDTEKKEIEGIRVRLEREISALKRHVDALEEEKGKTEKAVRETMNERRAIDKSLASMERENQ 1775
Cdd:PTZ00121 1695 KKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKK 1758
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
650-1203 2.97e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.29  E-value: 2.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  650 DQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANG---EIDILKAELTRLHEQVNERTRQISEAN 726
Cdd:PRK03918  193 ELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEElekELESLEGSKRKLEEKIRELEERIEELK 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  727 EKYDDAaRKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLRgnfdKLTNELKQKGVTVDSLNEEI 806
Cdd:PRK03918  273 KEIEEL-EEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIE----ERIKELEEKEERLEELKKKL 347

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  807 SSLKEQLNKSEKERKEELLRMEELEQKNEAEMK------EEYEVKLQLAEKDRQGVENFGKECEARMNELTKIHEMLMEE 880
Cdd:PRK03918  348 KELEKRLEELEERHELYEEAKAKKEELERLKKRltgltpEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKA 427

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  881 HDQLK--------VDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRLEssKNEAVTELQERVQKLEDVVKEK 952
Cdd:PRK03918  428 IEELKkakgkcpvCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELR--ELEKVLKKESELIKLKELAEQL 505

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  953 EDKEIALRR----DLEDSHEKSRDLDDKLRKMEltdeekeedrkKEQKTLNEERMKLMEQKEEAMLVATKhattidqqtr 1028
Cdd:PRK03918  506 KELEEKLKKynleELEKKAEEYEKLKEKLIKLK-----------GEIKSLKKELEKLEELKKKLAELEKK---------- 564

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1029 risvlEGDVEKltagiaERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERKKIQ 1108
Cdd:PRK03918  565 -----LDELEE------ELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFE 633

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1109 DLADQLREANKVVHNMRMKNVNLEEKKNEldqnvtDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNEQ 1188
Cdd:PRK03918  634 ELAETEKRLEELRKELEELEKKYSEEEYE------ELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707

                         570
                  ....*....|....*
gi 133903949 1189 FRLTDLEKVRKALQD 1203
Cdd:PRK03918  708 KAKKELEKLEKALER 722
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1371-1860 5.11e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.52  E-value: 5.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1371 TLRFLKERIEQLEADNADLSDALEKAKDELRQRNEKLADRQMVIERVERQLVHITEERNTIENRmtsqrqmyltnEESSR 1450
Cdd:PRK03918  173 EIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEEL-----------KEEIE 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1451 SREHEIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDALESKEKATGLVGVQDSKHRDLEEQLD---RANRERE 1527
Cdd:PRK03918  242 ELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREiekRLSRLEE 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1528 LAIGKQRRtLAENENLFRKLEQLEKEREQLMREITderRLNERNRTSLEELRVSERTWKSAMTTAKKPAEEQERAVQEQR 1607
Cdd:PRK03918  322 EINGIEER-IKELEEKEERLEELKKKLKELEKRLE---ELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELE 397

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1608 RWEESNHEMTNRNTALTKECDRLRVEMRDQLNRMNGINL------RSVDFERKNEELSSKLIVMQNTVTAMKKFEEEWKR 1681
Cdd:PRK03918  398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGkcpvcgRELTEEHRKELLEEYTAELKRIEKELKEIEEKERK 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1682 LEAEMRAELKILRKE----KLMQTAE-------------IEDLKRKSF-------RSDTEKKEIEGIRVRLEReISALKR 1737
Cdd:PRK03918  478 LRKELRELEKVLKKEseliKLKELAEqlkeleeklkkynLEELEKKAEeyeklkeKLIKLKGEIKSLKKELEK-LEELKK 556

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1738 HVDALEEEKGKTEKAVRETMNERRAID-KSLASMERENQQL---YRNCAQLQAQIQNLER-----DAGNRSVTKLAKEHS 1808
Cdd:PRK03918  557 KLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELepfYNEYLELKDAEKELEReekelKKLEEELDKAFEELA 636

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|...
gi 133903949 1809 LLEARIAALIEEKRQLQSMLDQKDANYSHKRKL-LESQIQLLREQLEAERRKR 1860
Cdd:PRK03918  637 ETEKRLEELRKELEELEKKYSEEEYEELREEYLeLSRELAGLRAELEELEKRR 689
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
399-614 6.15e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.09  E-value: 6.15e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  399 DESREAAKQAEKERDRAKKDLEKEEKRRKDdreaerkrssvYsQREHDLKKLDDELRKASEKIRNLEEQRESQEKLTISV 478
Cdd:COG3206   171 EEARKALEFLEEQLPELRKELEEAEAALEE-----------F-RQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEA 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  479 QNSLNEAHRQHKQFIEELMIRHREELKEREDSHEEALRSKDTEERSRFEKERSEREKIRRESDELR-ETQRSLKGDVAAM 557
Cdd:COG3206   239 EARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRaQLQQEAQRILASL 318

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 133903949  558 KTDLDDKTLRLDMLETERDELKKKL----ETEREQAD-QRDLEIAecRAKLDEMAEKEAELR 614
Cdd:COG3206   319 EAELEALQAREASLQAQLAQLEARLaelpELEAELRRlEREVEVA--RELYESLLQRLEEAR 378
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 406-1176 6.59e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.04  E-value: 6.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   406 KQAEKERDRAKKDLEKEEKRRKDDREAERKRSSVYSQREHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQNSLNEA 485
Cdd:TIGR00618  159 KAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQT 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   486 HRQHKQFIEELMIRHREELKEREDSHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQR--SLKGDVAAMKTDLDD 563
Cdd:TIGR00618  239 QQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAvtQIEQQAQRIHTELQS 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   564 K-TLRLDMLETERDELKKKLETEREQADQRDLEIAECR--------AKLDEMAEKEAELRKELAEFQAIITAMEGEGKLN 634
Cdd:TIGR00618  319 KmRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHirdahevaTSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   635 QEQFLESKNELNTLTDQIESLNSEVENK---NEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRL 711
Cdd:TIGR00618  399 CKELDILQREQATIDTRTSAFRDLQGQLahaKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTK 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   712 hEQVNERTRQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNE 791
Cdd:TIGR00618  479 -EQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQ 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   792 LKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEKDRQGVenfgkecEARMNELT 871
Cdd:TIGR00618  558 RASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQ-------PEQDLQDV 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   872 KIHEMLMEEHDQLKVDHLHTEEEvERLKEKMRKELEKLNEQndgdraewsneRNRLESSKNEAVTELQERVQKLEDVVKE 951
Cdd:TIGR00618  631 RLHLQQCSQELALKLTALHALQL-TLTQERVREHALSIRVL-----------PKELLASRQLALQKMQSEKEQLTYWKEM 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   952 KEDKEIALRrdleDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEEAMlvatKHATTIDQQ-TRRI 1030
Cdd:TIGR00618  699 LAQCQTLLR----ELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVL----KARTEAHFNnNEEV 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1031 SVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSelkngkeglsekwneerKKIQDL 1110
Cdd:TIGR00618  771 TAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLV-----------------QEEEQF 833

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 133903949  1111 ADQLREANKVVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHD 1176
Cdd:TIGR00618  834 LSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQFDGDALIKFLHE 899
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
521-960 6.76e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.84  E-value: 6.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  521 EERSRFEKERSEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERD--ELKKKLETEREQADQRDLEIAE 598
Cdd:COG4717    71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPLYQELEALEAELAELPERLEE 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  599 CRAKLDEMAEKEAELRKELAEFQAIITAMEgegKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEV 678
Cdd:COG4717   151 LEERLEELRELEEELEELEAELAELQEELE---ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEE 227

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  679 HIQNVRTS--SHQLTATYEEANGEIDILKAELTRLHEQVNertrqISEANEKYDDAARKNDALLEDVATWQEKYE-QLKM 755
Cdd:COG4717   228 ELEQLENEleAAALEERLKEARLLLLIAAALLALLGLGGS-----LLSLILTIAGVLFLVLGLLALLFLLLAREKaSLGK 302

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  756 ELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQlnKSEKERKEELLRMEELEQKNE 835
Cdd:COG4717   303 EAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEEL--EEELQLEELEQEIAALLAEAG 380

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  836 AEMKEEYEVKLQLAEKDRQGVENFgKECEARMNELTKIHEMLMEEHD--QLKVDHLHTEEEVERLKEkmrkELEKLNEQn 913
Cdd:COG4717   381 VEDEEELRAALEQAEEYQELKEEL-EELEEQLEELLGELEELLEALDeeELEEELEELEEELEELEE----ELEELREE- 454

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 133903949  914 dgdRAEWSNERNRLESSknEAVTELQERVQKLEDVVKEKEDKEIALR 960
Cdd:COG4717   455 ---LAELEAELEQLEED--GELAELLQELEELKAELRELAEEWAALK 496
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1371-1582 7.42e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 47.70  E-value: 7.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1371 TLRFLKERIEQLEADnadlSDALEKAKDELRQRN--------EKLADRQmvIERVERQLVHITEERNTIENRMTS-QRQM 1441
Cdd:COG3206   176 ALEFLEEQLPELRKE----LEEAEAALEEFRQKNglvdlseeAKLLLQQ--LSELESQLAEARAELAEAEARLAAlRAQL 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1442 YLTNEESSRSREH-EIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDALESKEKATGLVGVQdskhrdLEEQLD 1520
Cdd:COG3206   250 GSGPDALPELLQSpVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILAS------LEAELE 323

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 133903949 1521 RAN-RERELaigkqRRTLAENENLFRKLEQLEKEREQLMREITDERRLNERNRTSLEELRVSE 1582
Cdd:COG3206   324 ALQaREASL-----QAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAE 381
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1556-1862 1.04e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 47.43  E-value: 1.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1556 QLMREITDERRLNERNRTSLEELRVSERTwksamttaKKPAEEQERAVQEQRRWEESN---HEMTNRNTALTKECDRLRV 1632
Cdd:pfam17380  273 QLLHIVQHQKAVSERQQQEKFEKMEQERL--------RQEKEEKAREVERRRKLEEAEkarQAEMDRQAAIYAEQERMAM 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1633 EMRDQLNRmnginLRSVDFERKNEELSSKLIVMQ-NTVTAMKKFEEEWKRLEAEMRAELKILRKEKLMQtaeiedlKRKS 1711
Cdd:pfam17380  345 ERERELER-----IRQEERKRELERIRQEEIAMEiSRMRELERLQMERQQKNERVRQELEAARKVKILE-------EERQ 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1712 FRSDTEKKEIEGIRVRLEreiSALKRHVDALEEEKGKTEKAVRETMNERRAIDKSLASMERENQQLYRNCAQLQAQIQNL 1791
Cdd:pfam17380  413 RKIQQQKVEMEQIRAEQE---EARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRA 489

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 133903949  1792 ERDagNRSVtkLAKEhslLEARIAALIEEKRQL----QSMLDQKDANYSHKRKLLESQIQllREQLEAERRKRTK 1862
Cdd:pfam17380  490 EEQ--RRKI--LEKE---LEERKQAMIEEERKRklleKEMEERQKAIYEEERRREAEEER--RKQQEMEERRRIQ 555
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1372-1777 1.15e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.34  E-value: 1.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1372 LRFLKERIEQLEADNADLSD--ALEKAKDE-LRQRNEKLADRQMVI-ERVERQLVHITEERNTIEnrmtSQRQMYLTNEE 1447
Cdd:PRK02224  281 VRDLRERLEELEEERDDLLAeaGLDDADAEaVEARREELEDRDEELrDRLEECRVAAQAHNEEAE----SLREDADDLEE 356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1448 SSRSREHEIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDALESKEKATGLvgvqdskHRDLEEQLDRAN---R 1524
Cdd:PRK02224  357 RAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDF-------LEELREERDELRereA 429

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1525 ERELAIGKQRRTLAENENLFRK---------------LEQLEKEREQLmREITDERRLNERNRTSLEELRVSERTWKSAM 1589
Cdd:PRK02224  430 ELEATLRTARERVEEAEALLEAgkcpecgqpvegsphVETIEEDRERV-EELEAELEDLEEEVEEVEERLERAEDLVEAE 508

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1590 TTAKKPAEEQERAVQEQRRWEESNHEMTNRNTALTKECDRLRVEMRDQLNRMNGINLRSVDFERKNEELSSKLIVMQNTV 1669
Cdd:PRK02224  509 DRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERI 588

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1670 TAMKKFEEEWKRLEaEMRAELKILRkEKLMQTAEIEDLKRKSFRSDTEKKEIEGIRVRLEReISALKRHVDALEEEKGKT 1749
Cdd:PRK02224  589 ESLERIRTLLAAIA-DAEDEIERLR-EKREALAELNDERRERLAEKRERKRELEAEFDEAR-IEEAREDKERAEEYLEQV 665

                         410       420
                  ....*....|....*....|....*...
gi 133903949 1750 EKAVRETMNERRAIDKSLASMERENQQL 1777
Cdd:PRK02224  666 EEKLDELREERDDLQAEIGAVENELEEL 693
PRK01156 PRK01156
chromosome segregation protein; Provisional
 289-853 1.50e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 46.82  E-value: 1.50e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  289 IRHAEQKNLDQKEQMKREKddVLDETLrQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDELSDI---LEQLSK 365
Cdd:PRK01156  135 VGQGEMDSLISGDPAQRKK--ILDEIL-EINSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIkkqIADDEK 211

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  366 MAHEMAGGRGRNETPMDVARKMRKLLTTKNGEIDESREAAKQAEKERDRAKKDLEKEEKRRKDDREAERK-----RSSVY 440
Cdd:PRK01156  212 SHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERhmkiiNDPVY 291

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  441 SQREH--DLKKLDDELRKASEKIRNLEEQRESQEkltiSVQNSLNEAHRQHKQFIE-----ELMIRHREELKEREDSHEE 513
Cdd:PRK01156  292 KNRNYinDYFKYKNDIENKKQILSNIDAEINKYH----AIIKKLSVLQKDYNDYIKkksryDDLNNQILELEGYEMDYNS 367

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  514 ALRSKDTEERsrfeKERSEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQ-- 591
Cdd:PRK01156  368 YLKSIESLKK----KIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDEls 443

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  592 RDLEIAECRAK----------------LDEMAEKEAELRKELAEFQAIITAMEGEGK--LNQEQFLESK--NELNTLTDQ 651
Cdd:PRK01156  444 RNMEMLNGQSVcpvcgttlgeeksnhiINHYNEKKSRLEEKIREIEIEVKDIDEKIVdlKKRKEYLESEeiNKSINEYNK 523

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  652 IESLNSEVenknEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEiDILKAELTRLHEQVNERTRQISEANEKYDD 731
Cdd:PRK01156  524 IESARADL----EDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSKRT-SWLNALAVISLIDIETNRSRSNEIKKQLND 598

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  732 AARKNDAL---LEDVATWQEKYEQlKMELEEMNRRGQEKEREeaDLRALLDDLRGNFDKLTNELKQKGVTVDSLNE---E 805
Cdd:PRK01156  599 LESRLQEIeigFPDDKSYIDKSIR-EIENEANNLNNKYNEIQ--ENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEitsR 675

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*...
gi 133903949  806 ISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEKDR 853
Cdd:PRK01156  676 INDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINE 723
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
944-1410 1.63e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.57  E-value: 1.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  944 KLEDVVKEKEDKEIALRRDLEDSHEKSRDLDDKLRKMELTD--------EEKEEDRKKEQKTLNEERMKLMEQKEEAMLV 1015
Cdd:PRK02224  163 KLEEYRERASDARLGVERVLSDQRGSLDQLKAQIEEKEEKDlherlnglESELAELDEEIERYEEQREQARETRDEADEV 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1016 ATKHATTIDqqtrRISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEG 1095
Cdd:PRK02224  243 LEEHEERRE----ELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREE 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1096 LSEKWNEERKKIQDLADQLREANKVVHNMRmknvnleEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEH 1175
Cdd:PRK02224  319 LEDRDEELRDRLEECRVAAQAHNEEAESLR-------EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEE 391

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1176 DAQSMLKQAQNEQFRLTDLEKVRKALQDENQRLVNDLATVKAAFEVKRETSKSAI-----------------SDILDKYR 1238
Cdd:PRK02224  392 EIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEalleagkcpecgqpvegSPHVETIE 471

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1239 SAEEKANKGELDNQRLRSDLATVTLKLERQElkakdsdnRLRDSQKRFEEVQSKLANLQKSAVEslqnpmssnsrQNRSI 1318
Cdd:PRK02224  472 EDRERVEELEAELEDLEEEVEEVEERLERAE--------DLVEAEDRIERLEERREDLEELIAE-----------RRETI 532

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1319 YVDIPRAASsigLNENSDEvpLRSSPSVRFADSSQNMQRAVDSMDVSSSVGVTLRFLKERIEQLE------ADNADLSDA 1392
Cdd:PRK02224  533 EEKRERAEE---LRERAAE--LEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLErirtllAAIADAEDE 607

                         490       500
                  ....*....|....*....|....*
gi 133903949 1393 LEKAKDEL-------RQRNEKLADR 1410
Cdd:PRK02224  608 IERLREKRealaelnDERRERLAEK 632
PTZ00121 PTZ00121
MAEBL; Provisional
 1380-1822 1.94e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.67  E-value: 1.94e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1380 EQLEADNADLSDALEKAKDELRQRNEKLADRQMVIERVER---------QLVHITEERNTIENRMTSQRQMYLTNEESSR 1450
Cdd:PTZ00121 1192 ELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKaeeakkdaeEAKKAEEERNNEEIRKFEEARMAHFARRQAA 1271

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1451 SREHEIRSMKaristlELHLREKESKLAHLRKEIEVLHG-QLHDALESKEKATGLvgvqDSKHRDLEEQLDRANRERELA 1529
Cdd:PTZ00121 1272 IKAEEARKAD------ELKKAEEKKKADEAKKAEEKKKAdEAKKKAEEAKKADEA----KKKAEEAKKKADAAKKKAEEA 1341

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1530 IGKQRRTLAENENLFRKLEQLEKEREQLMREITDERRLNERNRTSLEELRVSERTWKSAmTTAKKPAEEQERAVQEQRRW 1609
Cdd:PTZ00121 1342 KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKA-EEDKKKADELKKAAAAKKKA 1420

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1610 EESNHEMTNRNTALTKECDRLRVEMRDQLNRmnginlrSVDFERKNEELSSKLIVMQNTVTAMKKFEEEWKRLEAEMRAE 1689
Cdd:PTZ00121 1421 DEAKKKAEEKKKADEAKKKAEEAKKADEAKK-------KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE 1493

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1690 LKILRKEKLMQTAEIEDLKRKSFRSDTEKKEIEGIRVRLEREISALKRhvdalEEEKGKTEKaVRETMNERRAIDKSLAS 1769
Cdd:PTZ00121 1494 EAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKK-----AEEKKKADE-LKKAEELKKAEEKKKAE 1567

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 133903949 1770 MERENQQlYRNCAQLQAQIQNLERDAGNRSVTKLAKEHSLLEARIAALIEEKR 1822
Cdd:PTZ00121 1568 EAKKAEE-DKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAK 1619
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 643-1318 2.01e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.55  E-value: 2.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   643 NELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVrtsshqltatyeeaNGEIDILKAELTRLHEQVNERTRQI 722
Cdd:TIGR04523   33 TEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNS--------------NNKIKILEQQIKDLNDKLKKNKDKI 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   723 SEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSL 802
Cdd:TIGR04523   99 NKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLL 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   803 NEEISSLKEQLNKSEKERKEELLRMEELEQKNEaemkEEYEVKLQLAEKDRQgVENFGKECEARMNELTKIHEMLMEEHD 882
Cdd:TIGR04523  179 EKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQ----KNKSLESQISELKKQ-NNQLKDNIEKKQQEINEKTTEISNTQT 253

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   883 QLKVDHLHTEEEVERLKEKmRKELEKLNEQNDGDRAEWSNERNRLESSKNEAVtelQERVQKLEDVVKEKEDKEIALRRD 962
Cdd:TIGR04523  254 QLNQLKDEQNKIKKQLSEK-QKELEQNNKKIKELEKQLNQLKSEISDLNNQKE---QDWNKELKSELKNQEKKLEEIQNQ 329

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   963 LEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEEAmlvaTKHATTIDQQTRRISVLEGDVEKLTA 1042
Cdd:TIGR04523  330 ISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKEN----QSYKQEIKNLESQINDLESKIQNQEK 405

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1043 GIAERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERKKIQDLadqLREANKVVH 1122
Cdd:TIGR04523  406 LNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVL---SRSINKIKQ 482

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1123 NMRMKNVNLEEKKNELDQnvtdLTNKVRQLEIQLMDKAAKnevsgdllrkmehdaQSMLKQAQNEqfrltdlekvrkalq 1202
Cdd:TIGR04523  483 NLEQKQKELKSKEKELKK----LNEEKKELEEKVKDLTKK---------------ISSLKEKIEK--------------- 528

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1203 denqrlvndlatvkaaFEVKRETSKSAISDILDKYRSAEEKANKGELDNQRLRSDLATVTLKLERQELKAKDS--DNRLR 1280
Cdd:TIGR04523  529 ----------------LESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEekQELID 592

                          650       660       670
                   ....*....|....*....|....*....|....*...
gi 133903949  1281 DSQKRFEEVQSKLANLQKSaVESLQNPMSSNSRQNRSI 1318
Cdd:TIGR04523  593 QKEKEKKDLIKEIEEKEKK-ISSLEKELEKAKKENEKL 629
PRK12705 PRK12705
hypothetical protein; Provisional
 402-533 2.10e-04

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 46.24  E-value: 2.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  402 REAAKQAEKERDRAKKDL-EKEEKRRKDDREAERKRSSVYSQREHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQN 480
Cdd:PRK12705   40 QEAQKEAEEKLEAALLEAkELLLRERNQQRQEARREREELQREEERLVQKEEQLDARAEKLDNLENQLEEREKALSAREL 119

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  481 SLNEAHRQHKQFIEELMIRHREELK-------EREDSHEEALRSKDTEERSRFEKERSER 533
Cdd:PRK12705  120 ELEELEKQLDNELYRVAGLTPEQARklllkllDAELEEEKAQRVKKIEEEADLEAERKAQ 179
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1390-1617 2.59e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 2.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1390 SDALEKAKDELRQRNEKLADRQMVIERVERQLVHITEERNTIENRMTSQRQmyltneessrsrehEIRSMKARISTLELH 1469
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALAR--------------RIRALEQELAALEAE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1470 LREKESKLAHLRKEIEVLHGQLHDAL------ESKEKATGLVGVQDSKH--RDLeEQLDRANRERELAIGKQRRTLAENE 1541
Cdd:COG4942    85 LAELEKEIAELRAELEAQKEELAELLralyrlGRQPPLALLLSPEDFLDavRRL-QYLKYLAPARREQAEELRADLAELA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1542 NLFRKLEQLEKEREQLMREITDERR----LNERNRTSLEELRVSERTWKSAMTTAKKPAEEQERAVQEQRRWEESNHEMT 1617
Cdd:COG4942   164 ALRAELEAERAELEALLAELEEERAaleaLKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 300-619 3.69e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.73  E-value: 3.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   300 KEQMKREKDDVLDETlRQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDElsdileQLSKMAHEMAGGRGRnET 379
Cdd:TIGR00618  562 KEQMQEIQQSFSILT-QCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHA------LLRKLQPEQDLQDVR-LH 633

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   380 PMDVARKMRKLLTTKNGEideSREAAKQAEKERDRAKKDLEKE--EKRRKDDREAERKRSSVYSQREhDLKKLDDELRKA 457
Cdd:TIGR00618  634 LQQCSQELALKLTALHAL---QLTLTQERVREHALSIRVLPKEllASRQLALQKMQSEKEQLTYWKE-MLAQCQTLLREL 709

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   458 SEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQFIEELMIRHREELKEREDSHEEALRSKDTEERSRFEKERSEREkIR 537
Cdd:TIGR00618  710 ETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAE-IQ 788

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   538 RESDELRETQRSLKGDVAAMKT----DLDDKTLRLDMLETERDELKKKLE---TEREQADQRDLEIAECRAKLDEMAEKE 610
Cdd:TIGR00618  789 FFNRLREEDTHLLKTLEAEIGQeipsDEDILNLQCETLVQEEEQFLSRLEeksATLGEITHQLLKYEECSKQLAQLTQEQ 868


                   ....*....
gi 133903949   611 AELRKELAE 619
Cdd:TIGR00618  869 AKIIQLSDK 877
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
501-624 4.01e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 45.23  E-value: 4.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  501 REELKEREDSHEEALRSKDTEERSRfekeRSEREKIRResdeLRETQRSLKGDVAAMKTDLDDKTLRLDMLETE----RD 576
Cdd:COG2433   384 ELIEKELPEEEPEAEREKEHEEREL----TEEEEEIRR----LEEQVERLEAEVEELEAELEEKDERIERLERElseaRS 455

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 133903949  577 ELKKKLETEREqADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAII 624
Cdd:COG2433   456 EERREIRKDRE-ISRLDREIERLERELEEERERIEELKRKLERLKELW 502
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1387-1713 4.42e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.49  E-value: 4.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1387 ADLSDALEKAKDELRQRNEKLADRQMVIERVERQLVHIT----------EERNTIENRMTSQRQMYLTNEESSRSREHEI 1456
Cdd:pfam15921  464 SSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTaslqekeraiEATNAEITKLRSRVDLKLQELQHLKNEGDHL 543

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1457 RSMKARISTLELHLREKESKLAHLRKEIEVL------HGQLHDALESK----EKATGLVGVQDSKHRDLEEQLDRANRER 1526
Cdd:pfam15921  544 RNVQTECEALKLQMAEKDKVIEILRQQIENMtqlvgqHGRTAGAMQVEkaqlEKEINDRRLELQEFKILKDKKDAKIREL 623

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1527 E-----LAIGKQRRTLAENENLfRKLEQLEKEREQLMREITDERrlNERNRTSlEELRVSERTWKSamttAKKPAEEQER 1601
Cdd:pfam15921  624 EarvsdLELEKVKLVNAGSERL-RAVKDIKQERDQLLNEVKTSR--NELNSLS-EDYEVLKRNFRN----KSEEMETTTN 695

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1602 AVQEQRRWEESNHEMTnRNTALTKECD-----RLRVEMRDQLNRMNGinlrsvdferKNEELSSKLIVMQNTVTAMKKFE 1676
Cdd:pfam15921  696 KLKMQLKSAQSELEQT-RNTLKSMEGSdghamKVAMGMQKQITAKRG----------QIDALQSKIQFLEEAMTNANKEK 764

                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 133903949  1677 EEWKRLEAEMRAELKILRKEKLMQTAEIEDLKRKSFR 1713
Cdd:pfam15921  765 HFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERR 801
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1193-1435 4.57e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 45.30  E-value: 4.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1193 DLEKVRKALQDENQRLVNDLATVKAAFEVKRETSKSA-ISDILDKYRSAEEKANKGELDNQRLR-SDLATVtlkLERQEL 1270
Cdd:PRK05771   17 YKDEVLEALHELGVVHIEDLKEELSNERLRKLRSLLTkLSEALDKLRSYLPKLNPLREEKKKVSvKSLEEL---IKDVEE 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1271 KAKDSDNRLRDSQKRFEEVQSKLANL--QKSAVESLQNPMSSNSRQNRSIYVDIprAASSIglNENSDEVPLRSSPSVRF 1348
Cdd:PRK05771   94 ELEKIEKEIKELEEEISELENEIKELeqEIERLEPWGNFDLDLSLLLGFKYVSV--FVGTV--PEDKLEELKLESDVENV 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1349 ADSSQNMQR----AVDSMDVSSSVGVTLRFL-------------KERIEQLEADNADLSDALEKAKDELRQRNEKLADRQ 1411
Cdd:PRK05771  170 EYISTDKGYvyvvVVVLKELSDEVEEELKKLgferleleeegtpSELIREIKEELEEIEKERESLLEELKELAKKYLEEL 249

                         250       260
                  ....*....|....*....|....
gi 133903949 1412 MVIErverQLVHITEERNTIENRM 1435
Cdd:PRK05771  250 LALY----EYLEIELERAEALSKF 269
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1363-1765 4.73e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.05  E-value: 4.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1363 DVSSSVGVTLRFLKERIEQLEADNADLSDALEKAKdELRQRNEKLADRQMVIERVERQLVHITEERNTIENrmTSQRQMY 1442
Cdd:PRK03918  307 DELREIEKRLSRLEEEINGIEERIKELEEKEERLE-ELKKKLKELEKRLEELEERHELYEEAKAKKEELER--LKKRLTG 383

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1443 LTNEESsrsrEHEIRSMKARISTLELHLREKESKLAHLRKEIevlhGQLHDALESKEKATGLVGVqdSKHRDLEEQLDRA 1522
Cdd:PRK03918  384 LTPEKL----EKELEELEKAKEEIEEEISKITARIGELKKEI----KELKKAIEELKKAKGKCPV--CGRELTEEHRKEL 453

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1523 NRERELAIGKQRRTLAENENlfrKLEQLEKEREQLMREITDERRLNeRNRTSLEELR-VSERTWKSAMTTAKKPAEEQER 1601
Cdd:PRK03918  454 LEEYTAELKRIEKELKEIEE---KERKLRKELRELEKVLKKESELI-KLKELAEQLKeLEEKLKKYNLEELEKKAEEYEK 529

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1602 AVQEQRRWE----------ESNHEMTNRNTALTKECDRLRVEMRDQLNRMNGINLRSV-DFERKNEELSS---KLIVMQN 1667
Cdd:PRK03918  530 LKEKLIKLKgeikslkkelEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVeELEERLKELEPfynEYLELKD 609

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1668 TVTAMKKFEEEWKRLEAEM---RAELKILRKEKLMQTAEIEDLKRKSfrSDTEKKEIEGIRVRLEREISALKRHVDALEE 1744
Cdd:PRK03918  610 AEKELEREEKELKKLEEELdkaFEELAETEKRLEELRKELEELEKKY--SEEEYEELREEYLELSRELAGLRAELEELEK 687

                         410       420
                  ....*....|....*....|.
gi 133903949 1745 EKGKTEKAVRETMNERRAIDK 1765
Cdd:PRK03918  688 RREEIKKTLEKLKEELEEREK 708
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 998-1218 4.88e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 4.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  998 LNEERMKLMEQKEEAMLVATKHATTIDQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAELEKLKD 1077
Cdd:COG4942    25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKE 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1078 ELAVMLK---QNSELKNGKEGLSekwneeRKKIQDLADQLREANKVVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEI 1154
Cdd:COG4942   105 ELAELLRalyRLGRQPPLALLLS------PEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 133903949 1155 QLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNEQFRLTDLEKVRKALQDENQRLVNDLATVKAA 1218
Cdd:COG4942   179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1378-1532 5.38e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.76  E-value: 5.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1378 RIEQLEADNADLSDALEKAKDELRQRNEKLADRQMVIERVERQLVHITEERNTIENRMT--SQRQMYLTNEESSRSREHE 1455
Cdd:COG1579    18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKkyEEQLGNVRNNKEYEALQKE 97

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 133903949 1456 IRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDAlesKEKATGLVGVQDSKHRDLEEQLDRANRERELAIGK 1532
Cdd:COG1579    98 IESLKRRISDLEDEILELMERIEELEEELAELEAELAEL---EAELEEKKAELDEELAELEAELEELEAEREELAAK 171
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 292-471 5.66e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 5.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  292 AEQKNLDQKEQMKREKDDVLDETLRQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQLSKMAHEMA 371
Cdd:COG4942    38 ELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLG 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  372 GGRG-----RNETPMDVARKMR--------------------KLLTTKNGEIDESREAAKQAEKERDRAKKDLEKEEKRR 426
Cdd:COG4942   118 RQPPlalllSPEDFLDAVRRLQylkylaparreqaeelradlAELAALRAELEAERAELEALLAELEEERAALEALKAER 197

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 133903949  427 KDDREAERKRSSVYSQREHDLKKLDDELRKASEKIRNLEEQRESQ 471
Cdd:COG4942   198 QKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 441-1297 6.13e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 45.04  E-value: 6.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   441 SQREHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQFIEELMIRHREELK---EREDSHEEALRS 517
Cdd:TIGR01612  768 SNKINDYAKEKDELNKYKSKISEIKNHYNDQINIDNIKDEDAKQNYDKSKEYIKTISIKEDEIFKiinEMKFMKDDFLNK 847

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   518 KDTeersRFEKERSEREKIRRESDELRETQRSLKGDVAAMKtdLDDKTLRLDMLETERDELKKKLETEREQAD---QRDL 594
Cdd:TIGR01612  848 VDK----FINFENNCKEKIDSEHEQFAELTNKIKAEISDDK--LNDYEKKFNDSKSLINEINKSIEEEYQNINtlkKVDE 921

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   595 EIAECRA---KLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQF----LESKNELNTLTDQIeSLNSEVENKNEEIR 667
Cdd:TIGR01612  922 YIKICENtkeSIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFdntlIDKINELDKAFKDA-SLNDYEAKNNELIK 1000

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   668 ---NLMATL------------QEKEVHIQNVRTSShqLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDA 732
Cdd:TIGR01612 1001 yfnDLKANLgknkenmlyhqfDEKEKATNDIEQKI--EDANKNIPNIEIAIHTSIYNIIDEIEKEIGKNIELLNKEILEE 1078

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   733 ARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQ 812
Cdd:TIGR01612 1079 AEINITNFNEIKEKLKHYNFDDFGKEENIKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDV 1158

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   813 LNKS-------EKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEKDRQGVE-------NFGK-----------ECEARM 867
Cdd:TIGR01612 1159 ADKAisnddpeEIEKKIENIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTSLEevkginlSYGKnlgklflekidEEKKKS 1238

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   868 NELTKIHEMLMEEHDQLKVDHLHTEEEVErLKEKMRKELEKLNEQNDGDRAEWSNERNRlesskNEAVTELQERVQKL-E 946
Cdd:TIGR01612 1239 EHMIKAMEAYIEDLDEIKEKSPEIENEMG-IEMDIKAEMETFNISHDDDKDHHIISKKH-----DENISDIREKSLKIiE 1312

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   947 DVVKEKEDKEI--ALRRDLEDSHEKSRDLDDKLRKM----------ELTDEEKEEDRKKEQKTLNEERMKLMEQKEEAML 1014
Cdd:TIGR01612 1313 DFSEESDINDIkkELQKNLLDAQKHNSDINLYLNEIaniynilklnKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLI 1392

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1015 VATKHATTIDQQTRRI-SVLEG-DVEKLTAGIAERESSINALESNTMELISKL-ETTEAELEKLKDELAVMLKQNSELKN 1091
Cdd:TIGR01612 1393 KKIKDDINLEECKSKIeSTLDDkDIDECIKKIKELKNHILSEESNIDTYFKNAdENNENVLLLFKNIEMADNKSQHILKI 1472

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1092 GKEGLSekwNEERKKIQDLADQLREANKvVHNMRMKNVNLEEKKNEL----DQNVTDLTNKVRQLEIQLMDKAAKN---- 1163
Cdd:TIGR01612 1473 KKDNAT---NDHDFNINELKEHIDKSKG-CKDEADKNAKAIEKNKELfeqyKKDVTELLNKYSALAIKNKFAKTKKdsei 1548

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1164 ------EVSGDLLRKMEHDAQSMlKQAQNEQFRLTDlekvRKALQDENQRLVNDLATVKAAFE---VKRETSKSAISDIL 1234
Cdd:TIGR01612 1549 iikeikDAHKKFILEAEKSEQKI-KEIKKEKFRIED----DAAKNDKSNKAAIDIQLSLENFEnkfLKISDIKKKINDCL 1623

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 133903949  1235 DKYRSAEEKANKGELDNQRLRSDLATVTLKLERQELKA-KDSDNRLRDSQKRFEEVQSKLANLQ 1297
Cdd:TIGR01612 1624 KETESIEKKISSFSIDSQDTELKENGDNLNSLQEFLESlKDQKKNIEDKKKELDELDSEIEKIE 1687
46 PHA02562
endonuclease subunit; Provisional
 690-971 6.23e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.62  E-value: 6.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  690 LTATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDA-ARKNDALLEDVatwqEKYEQLKMELEEMNRRGQEKE 768
Cdd:PHA02562  172 NKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENiARKQNKYDELV----EEAKTIKAEIEELTDELLNLV 247

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  769 REeadlralLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKE--------QLNKSEKERkeellrmeelEQKNEAEMKe 840
Cdd:PHA02562  248 MD-------IEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKggvcptctQQISEGPDR----------ITKIKDKLK- 309

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  841 EYEVKLQLAEKDRQgvenfgkECEARMNELTKIHEMLMEEHDQLKVDHLHTEEEVERLKeKMRKELEKLNEQNDGDRAEW 920
Cdd:PHA02562  310 ELQHSLEKLDTAID-------ELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAK-KVKAAIEELQAEFVDNAEEL 381

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 133903949  921 SnernrlessknEAVTELQERVQKLEDVVKEKEDKEIAlRRDLEDSHEKSR 971
Cdd:PHA02562  382 A-----------KLQDELDKIVKTKSELVKEKYHRGIV-TDLLKDSGIKAS 420
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
502-771 7.14e-04

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 43.75  E-value: 7.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  502 EELKEREDSHEEALRSKDTEERSRFEKERSEREKIrresDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKK 581
Cdd:COG1340    11 EELEEKIEELREEIEELKEKRDELNEELKELAEKR----DELNAQVKELREEAQELREKRDELNEKVKELKEERDELNEK 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  582 LETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEGEGKL------------NQEQFLESKNELNTLT 649
Cdd:COG1340    87 LNELREELDELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVLSPEEEKELvekikelekeleKAKKALEKNEKLKELR 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  650 DQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKY 729
Cdd:COG1340   167 AELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADELHKEIVEAQEKADELHEEIIELQKELRELRKEL 246

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 133903949  730 DDAARKNDALLEDVAtwQEKYEQLKMELEEMNRRGQEKEREE 771
Cdd:COG1340   247 KKLRKKQRALKREKE--KEELEEKAEEIFEKLKKGEKLTTEE 286
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
751-1299 7.41e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.67  E-value: 7.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  751 EQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKqkgvTVDSLNEEISSLKEQLNKSEKErkeellrmeel 830
Cdd:PRK03918  189 ENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVK----ELEELKEEIEELEKELESLEGS----------- 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  831 eqkneaemKEEYEVKLQLAEKDRQGVENFGKECEARMNELTKIHEmlmeehdqlkvdhlhTEEEVERLKEKMRKELEKLN 910
Cdd:PRK03918  254 --------KRKLEEKIRELEERIEELKKEIEELEEKVKELKELKE---------------KAEEYIKLSEFYEEYLDELR 310

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  911 EQNDGdRAEWSNERNRLEssknEAVTELQERVQKLEDVVKEKEDkeiaLRRDLEDSHEKSRDLDDKLRKMELTDEEKEED 990
Cdd:PRK03918  311 EIEKR-LSRLEEEINGIE----ERIKELEEKEERLEELKKKLKE----LEKRLEELEERHELYEEAKAKKEELERLKKRL 381

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  991 RKKEQKTLNEERMKLMEQKEEAMLVATKHATTIDQQTRRISVLEGDVEKLTAgiAERESSINALESNTMELISKLETTEA 1070
Cdd:PRK03918  382 TGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKK--AKGKCPVCGRELTEEHRKELLEEYTA 459

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1071 ELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERK--KIQDLADQLREANKvvhnmRMKNVNLEEkkneldqnvtdltnk 1148
Cdd:PRK03918  460 ELKRIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKELEE-----KLKKYNLEE--------------- 519

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1149 vrqleiqLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQneqfRLTDLEKVRKALQDENQRLVNDLAtvkaafEVKRETSKS 1228
Cdd:PRK03918  520 -------LEKKAEEYEKLKEKLIKLKGEIKSLKKELE----KLEELKKKLAELEKKLDELEEELA------ELLKELEEL 582

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 133903949 1229 AISDI--LDKYRSAEEKANKGELDNQRLRSDLATVTLKLERQELKAKDSDNRLRDSQKRFEEVQSKLANLQKS 1299
Cdd:PRK03918  583 GFESVeeLEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKK 655
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
903-1297 7.73e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.65  E-value: 7.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  903 RKELEKLNEQNDGDRAEWSNERNRLES--SKNEAVTELQERVQKLEDVVKEKEDKEIALRRDLEDSHEKSRDLDDKLRKM 980
Cdd:PRK02224  219 DEEIERYEEQREQARETRDEADEVLEEheERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDL 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  981 ELT---DEEKEEDRKKEQKTLNEERMKLMEQKEEAMLVATKHATTIDQQTRRI--------------SVLEGDVEKLTAG 1043
Cdd:PRK02224  299 LAEaglDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDAddleeraeelreeaAELESELEEAREA 378

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1044 IAERESSINALESNTMELISKLETTEAELEKLKDELAvmlkqnsELKNGKEGLSEKWNEERKKIQDLADQLREANKVVHN 1123
Cdd:PRK02224  379 VEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLE-------ELREERDELREREAELEATLRTARERVEEAEALLEA 451

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1124 MRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMD-KAAKNEVSGDLLRkmehdaqsmLKQAQNEQFRLTDLEKVRKALQ 1202
Cdd:PRK02224  452 GKCPECGQPVEGSPHVETIEEDRERVEELEAELEDlEEEVEEVEERLER---------AEDLVEAEDRIERLEERREDLE 522

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1203 DenqrLVNDLATVKAAFEVKRETSKSAISDILDKYRSAEEKANKGELDNQRLRSDLAtvTLKLERQELKAK-DSDNRLRD 1281
Cdd:PRK02224  523 E----LIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVA--ELNSKLAELKERiESLERIRT 596

                         410
                  ....*....|....*.
gi 133903949 1282 SQKRFEEVQSKLANLQ 1297
Cdd:PRK02224  597 LLAAIADAEDEIERLR 612
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1548-1859 8.16e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.67  E-value: 8.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1548 EQLEKEREQLMREITDERRLNERNRTSLEELRVSERTWKSAMTTAKKPAEEQERaVQEQRRWEESNHEMTNRNT--ALTK 1625
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKE-KREYEGYELLKEKEALERQkeAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1626 ECDRLRVEMRDQLNRMNGINLRSVDFERKNEELSSKLivmqntvtaMKKFEEEWKRLEAEMR---AELKILRKEKLMQTA 1702
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKI---------KDLGEEEQLRVKEKIGeleAEIASLERSIAEKER 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1703 EIEDLKRKSFRSDTEKKEIEGIRVRLEREISALKRHVDALEEEKGKTEKAVRETMNERRAIDKSLASMERENQQLYRNCA 1782
Cdd:TIGR02169  316 ELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLE 395

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 133903949  1783 QLQAQIQNLER--DAGNRSVTKLAKEHSLLEARIAALIEEKRQLQSMLDQKDAnyshKRKLLESQIQLLREQLEAERRK 1859
Cdd:TIGR02169  396 KLKREINELKRelDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKAL----EIKKQEWKLEQLAADLSKYEQE 470
PRK01156 PRK01156
chromosome segregation protein; Provisional
 701-1284 9.09e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 44.12  E-value: 9.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  701 IDILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDD 780
Cdd:PRK01156  185 IDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESD 264

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  781 LRGNFDKltnelkqkgvtvdslNEEISSLKEQLNKSEKERkeellrmeelEQKNEAEMKEEYEVKLQLAEKdRQGVENFG 860
Cdd:PRK01156  265 LSMELEK---------------NNYYKELEERHMKIINDP----------VYKNRNYINDYFKYKNDIENK-KQILSNID 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  861 KECEaRMNELTKIHEMLMEEHDQLkvdhlhteeeverlkEKMRKELEKLNEQNDGDRAEwsnernrlESSKNEAVTELQE 940
Cdd:PRK01156  319 AEIN-KYHAIIKKLSVLQKDYNDY---------------IKKKSRYDDLNNQILELEGY--------EMDYNSYLKSIES 374

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  941 RVQKLEDVVKEKEDKEIALRRDLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEEAMLVATKHA 1020
Cdd:PRK01156  375 LKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQSV 454

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1021 TTI-------DQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEA-ELEKLKDELAVMLKQNSELKNG 1092
Cdd:PRK01156  455 CPVcgttlgeEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESeEINKSINEYNKIESARADLEDI 534

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1093 KEGLSEKWNEERK-----------KIQDLADQLREANKVVHNMRMKNV-NLEEKKNELDQNVTDLTNKVRQLEIQLMDKA 1160
Cdd:PRK01156  535 KIKINELKDKHDKyeeiknrykslKLEDLDSKRTSWLNALAVISLIDIeTNRSRSNEIKKQLNDLESRLQEIEIGFPDDK 614

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1161 AKNEVSgdlLRKMEHDAQSMLKQAQNEQFRLTDLEKVRKALQDENQRLVNdlatvKAAFEVKRETSKSAISDILDKYRSA 1240
Cdd:PRK01156  615 SYIDKS---IREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAE-----IDSIIPDLKEITSRINDIEDNLKKS 686

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....
gi 133903949 1241 EEKANKGELDNQRLRSDLATVTLKLERQELKAKDSDNRLRDSQK 1284
Cdd:PRK01156  687 RKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKK 730
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 663-843 1.08e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.60  E-value: 1.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  663 NEEIRNLMaTLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDA---ARKNDAL 739
Cdd:COG1579     3 PEDLRALL-DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVearIKKYEEQ 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  740 LEDVATwQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKgvtVDSLNEEISSLKEQLNKSEKE 819
Cdd:COG1579    82 LGNVRN-NKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAEL---EAELEEKKAELDEELAELEAE 157

                         170       180
                  ....*....|....*....|....
gi 133903949  820 RKEELLRMEELEQKNEAEMKEEYE 843
Cdd:COG1579   158 LEELEAEREELAAKIPPELLALYE 181
PRK09039 PRK09039
peptidoglycan -binding protein;
529-656 1.12e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 43.42  E-value: 1.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  529 ERSEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQAdqrdleiAECRAKLDEMAE 608
Cdd:PRK09039   72 ERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQELDSEKQVS-------ARALAQVELLNQ 144

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 133903949  609 KEAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNT-LTDQIESLN 656
Cdd:PRK09039  145 QIAALRRQLAALEAALDASEKRDRESQAKIADLGRRLNVaLAQRVQELN 193
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1700-1862 1.37e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 1.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1700 QTAEIEDLKRKSFRSDTEKKEIEGIRVRLEREISALKRHVDALEEEKGKTEKAVRETMNERRAIDKSLASMERENQQLYR 1779
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1780 NCAQLQAQIQNLER-----------------DAGNRSVTKLAKEHSLLEARIAALIEEKRQLQSMLDQKDANYSHKRKL- 1841
Cdd:COG4942    98 ELEAQKEELAELLRalyrlgrqpplalllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELe 177

                         170       180
                  ....*....|....*....|..
gi 133903949 1842 -LESQIQLLREQLEAERRKRTK 1862
Cdd:COG4942   178 aLLAELEEERAALEALKAERQK 199
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1377-1859 1.39e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1377 ERIEQLEADNADLSDALEKAKDELRQRneKLADRQMVIERVERQLVHITEERNTIENRMTSQRQMYLTNEESSRSREHE- 1455
Cdd:COG4913   262 ERYAAARERLAELEYLRAALRLWFAQR--RLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDr 339

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1456 IRSMKARISTLELHLREKESKLAHLRKEIEVLHgqlhdaLESKEKATGLVGVQdskhRDLEEQLDRANRERELAIGKQRR 1535
Cdd:COG4913   340 LEQLEREIERLERELEERERRRARLEALLAALG------LPLPASAEEFAALR----AEAAALLEALEEELEALEEALAE 409

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1536 TLAENENLFRKLEQLEKEREQLMReitdeRRLN-----ERNRTSLE-----------------ELRVSERTWKSAMTTAK 1593
Cdd:COG4913   410 AEAALRDLRRELRELEAEIASLER-----RKSNiparlLALRDALAealgldeaelpfvgeliEVRPEEERWRGAIERVL 484

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1594 KPA-------EEQERAVqeqRRWEESNH-----------------------------EMTNRNTA--------LTKECDR 1629
Cdd:COG4913   485 GGFaltllvpPEHYAAA---LRWVNRLHlrgrlvyervrtglpdperprldpdslagKLDFKPHPfrawleaeLGRRFDY 561

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1630 LRVEMRDQLNRM------NGinLRSVDFER----KNEELSSKLIVMQNTVTAMKKFEEEWKRLEAEMRAELKILRK--EK 1697
Cdd:COG4913   562 VCVDSPEELRRHpraitrAG--QVKGNGTRhekdDRRRIRSRYVLGFDNRAKLAALEAELAELEEELAEAEERLEAleAE 639

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1698 LMQTAEIEDLKRKSFRSDTEKKEIEGIR---VRLEREISALKR---HVDALEEEKGKTEKAVRETMNERRAIDKSLASME 1771
Cdd:COG4913   640 LDALQERREALQRLAEYSWDEIDVASAEreiAELEAELERLDAssdDLAALEEQLEELEAELEELEEELDELKGEIGRLE 719

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1772 RENQQLYRNCAQLQAQIQNLERDAGnrsvtklAKEHSLLEARIAALIEEKRQlqsmlDQKDANYSHKRKLLESQIQLLRE 1851
Cdd:COG4913   720 KELEQAEEELDELQDRLEAAEDLAR-------LELRALLEERFAAALGDAVE-----RELRENLEERIDALRARLNRAEE 787


                  ....*...
gi 133903949 1852 QLEAERRK 1859
Cdd:COG4913   788 ELERAMRA 795
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 487-797 1.40e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 43.38  E-value: 1.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  487 RQHKQFIEELmirHREELKEREDSheealrsKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAMKTdlddktl 566
Cdd:PRK05771   16 SYKDEVLEAL---HELGVVHIEDL-------KEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKK------- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  567 rldMLETERDELKKKLETEREQADQRdleiaecrakLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQE--QFLESKN- 643
Cdd:PRK05771   79 ---VSVKSLEELIKDVEEELEKIEKE----------IKELEEEISELENEIKELEQEIERLEPWGNFDLDlsLLLGFKYv 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  644 --ELNTLT-DQIESLNSEVENKNEEIRNlmatlQEKEVHIQNVrtsshqLTATYEEANGEIDILKAELTRLHEQVNER-T 719
Cdd:PRK05771  146 svFVGTVPeDKLEELKLESDVENVEYIS-----TDKGYVYVVV------VVLKELSDEVEEELKKLGFERLELEEEGTpS 214

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  720 RQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRrgQEKEREEADLRALLDD----LRG-----NFDKLTN 790
Cdd:PRK05771  215 ELIREIKEELEEIEKERESLLEELKELAKKYLEELLALYEYLE--IELERAEALSKFLKTDktfaIEGwvpedRVKKLKE 292


                  ....*..
gi 133903949  791 ELKQKGV 797
Cdd:PRK05771  293 LIDKATG 299
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1371-1860 1.59e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.51  E-value: 1.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1371 TLRFLKERIEQLEADNADLSDALEKAKDELRQRNEKLADRQMVIERVERQLVHITEERNTIENRMTSQRQMYLTNEESSR 1450
Cdd:PRK03918  232 ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELRE 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1451 ------SREHEIRSMKARISTLE---LHLREKESKLAHLRKEIEVLHGQLHDALESKEKATGLvgvQDSKHRDLEEQLDR 1521
Cdd:PRK03918  312 iekrlsRLEEEINGIEERIKELEekeERLEELKKKLKELEKRLEELEERHELYEEAKAKKEEL---ERLKKRLTGLTPEK 388

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1522 ANRERELAIGKQRRTLAENENLFRKLEQLEKEREQLM-----------------REITDERRLNERNRTSLEELRVSERt 1584
Cdd:PRK03918  389 LEKELEELEKAKEEIEEEISKITARIGELKKEIKELKkaieelkkakgkcpvcgRELTEEHRKELLEEYTAELKRIEKE- 467

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1585 wksamttaKKPAEEQERAVQEQRRWEESNHEMTNRNTALTKECDRLRvEMRDQLNRMNGINLRSVdfERKNEELSSKLIV 1664
Cdd:PRK03918  468 --------LKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLK-ELEEKLKKYNLEELEKK--AEEYEKLKEKLIK 536

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1665 MQNTVTAMKKFEEEWKRLEAEMRAELKILRKEKLMQTAEIEDLKRKSFRSDTEKKEIEGIRVRLEREISALKRHVDALEE 1744
Cdd:PRK03918  537 LKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELER 616

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1745 EKGKTEKAVRETMNERRAIDKSLASMERenqqlyrncaqLQAQIQNLERDAGNRSVTKLAKEHSLLEARIAALIEEKRQL 1824
Cdd:PRK03918  617 EEKELKKLEEELDKAFEELAETEKRLEE-----------LRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEEL 685

                         490       500       510
                  ....*....|....*....|....*....|....*.
gi 133903949 1825 QSMLDQkdanyshkrklLESQIQLLREQLEAERRKR 1860
Cdd:PRK03918  686 EKRREE-----------IKKTLEKLKEELEEREKAK 710
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 179-854 2.02e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.18  E-value: 2.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   179 NNTLEEVNEMLREENDAALAANEHLRVDATNLSRQLQQLQQQQHTesmrfRSENTRYRNQTETQHRklislwkefTAVKR 258
Cdd:pfam15921   84 SHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDA-----MADIRRRESQSQEDLR---------NQLQN 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   259 QLHELrtttandldrqltEFTRCatlMRKAIRHAEQKNLDQKEQMKREKDDVLDETLRQLNSVTENYMKS-EEKANERQR 337
Cdd:pfam15921  150 TVHEL-------------EAAKC---LKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKiYEHDSMSTM 213

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   338 DLKRKEDECRK-LREQNDELSDILEQLSKMAHEMAGGRGRNETPMDV-----ARKMRKLLTTKNGEIDESREAAKQAEKE 411
Cdd:pfam15921  214 HFRSLGSAISKiLRELDTEISYLKGRIFPVEDQLEALKSESQNKIELllqqhQDRIEQLISEHEVEITGLTEKASSARSQ 293

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   412 RDRAKKDLEKEEkrrkddrEAERKRSSVYSQREHDLKKLDDELR-KASEKIRNLEEQRESQEKLTISVQNSLNEAHRQHK 490
Cdd:pfam15921  294 ANSIQSQLEIIQ-------EQARNQNSMYMRQLSDLESTVSQLRsELREAKRMYEDKIEELEKQLVLANSELTEARTERD 366

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   491 QFIEELMIRHREELKEREDSHEEalrskdteersrfEKERS-EREKIRRESDelRETQRSLKGDvaAMKTDLDDKTLRLD 569
Cdd:pfam15921  367 QFSQESGNLDDQLQKLLADLHKR-------------EKELSlEKEQNKRLWD--RDTGNSITID--HLRRELDDRNMEVQ 429

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   570 MLETERDELKKKLETEREQadqrdlEIAECRAKlDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLT 649
Cdd:pfam15921  430 RLEALLKAMKSECQGQMER------QMAAIQGK-NESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLT 502

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   650 DQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLtatyEEANGEIDILKAELTRLHEQVNERTRQISEANEKY 729
Cdd:pfam15921  503 ASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHL----RNVQTECEALKLQMAEKDKVIEILRQQIENMTQLV 578

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   730 DDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSL 809
Cdd:pfam15921  579 GQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQL 658

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 133903949   810 KEQLNKSEKERKEELLRMEELEQ--KNEAEMKEEYEVKLQLAEKDRQ 854
Cdd:pfam15921  659 LNEVKTSRNELNSLSEDYEVLKRnfRNKSEEMETTTNKLKMQLKSAQ 705
46 PHA02562
endonuclease subunit; Provisional
 632-820 2.28e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.69  E-value: 2.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  632 KLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIdilkaELTRL 711
Cdd:PHA02562  209 KKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVI-----KMYEK 283

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  712 HEQVNERTRQISEANEKYDDAARKNDAL---LEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKL 788
Cdd:PHA02562  284 GGVCPTCTQQISEGPDRITKIKDKLKELqhsLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKV 363

                         170       180       190
                  ....*....|....*....|....*....|..
gi 133903949  789 TNELKQKGVTVDSLNEEISSLKEQLNKSEKER 820
Cdd:PHA02562  364 KAAIEELQAEFVDNAEELAKLQDELDKIVKTK 395
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 292-485 2.29e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.51  E-value: 2.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  292 AEQKNLDQKEQMKREKDDVLDETLRQLNSVTENYMKSEEKANERQRDLKRKEDEcrkLREQNDELSDILEQLSKMAHEMA 371
Cdd:COG3883    20 AKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAE---IAEAEAEIEERREELGERARALY 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  372 GGrGRNETPMDV-------------ARKMRKLLTTKNGEIDESREAAKQAEKERDRAKKDLEKEEKRRKDDREAERKRSS 438
Cdd:COG3883    97 RS-GGSVSYLDVllgsesfsdfldrLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEA 175

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 133903949  439 VYSQREHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQNSLNEA 485
Cdd:COG3883   176 QQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAA 222
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1023-1207 2.35e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 2.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1023 IDQQTRRISVLEGDVEKLTA---GIAERESSINALESNTMELIsKLETTEAELEKLKDELAVMLKQNSELkngkEGLSEK 1099
Cdd:COG4913   619 LAELEEELAEAEERLEALEAeldALQERREALQRLAEYSWDEI-DVASAEREIAELEAELERLDASSDDL----AALEEQ 693

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1100 WNEERKKIQDLADQLREANKVVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQS 1179
Cdd:COG4913   694 LEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEE 773

                         170       180
                  ....*....|....*....|....*...
gi 133903949 1180 MLKQAQNEQFRLTdlEKVRKALQDENQR 1207
Cdd:COG4913   774 RIDALRARLNRAE--EELERAMRAFNRE 799
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 422-814 2.37e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.02  E-value: 2.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  422 EEKRRKDDREAERKRssvysQREHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQ------NSLNEAHRQhkqfiEE 495
Cdd:COG3096   278 NERRELSERALELRR-----ELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQaasdhlNLVQTALRQ-----QE 347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  496 LMIRHREELKEREDSHEEAlrskdTEERSRFEKERSEREKIRRESDElretqrslkgDVAAMKTDLDDKTLRLDMLET-- 573
Cdd:COG3096   348 KIERYQEDLEELTERLEEQ-----EEVVEEAAEQLAEAEARLEAAEE----------EVDSLKSQLADYQQALDVQQTra 412

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  574 ----------ER------------DELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEGEG 631
Cdd:COG3096   413 iqyqqavqalEKaralcglpdltpENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEVERSQ 492

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  632 KLNQ-EQFLESKNELNTLTDQIESLN---SEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAE 707
Cdd:COG3096   493 AWQTaRELLRRYRSQQALAQRLQQLRaqlAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQ 572

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  708 LTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEE----MNRRGQ--EKEREEADLRALLDDL 781
Cdd:COG3096   573 AAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEALADsqevTAAMQQllEREREATVERDELAAR 652

                         410       420       430
                  ....*....|....*....|....*....|...
gi 133903949  782 RGNFDKLTNELKQKGVTVDSlneEISSLKEQLN 814
Cdd:COG3096   653 KQALESQIERLSQPGGAEDP---RLLALAERLG 682
FPP pfam05911
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ...
 1336-1526 2.76e-03

Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.


Pssm-ID: 461778 [Multi-domain]  Cd Length: 859  Bit Score: 42.74  E-value: 2.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1336 DEVPLRSSPSVRFADSSQNMQRAVDSMDVSSSVGV---TLRFLKERIEQLEADNADLSDALEKAKDELRQRNEKLADRQM 1412
Cdd:pfam05911  644 NKVAQVDNGCSEIDNLSSDPEIPSDGPLVSGSNDLkteENKRLKEEFEQLKSEKENLEVELASCTENLESTKSQLQESEQ 723

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1413 VIERVERQLVhiteerntienrmtsqrqmylTNEESSRSREHEIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLH 1492
Cdd:pfam05911  724 LIAELRSELA---------------------SLKESNSLAETQLKCMAESYEDLETRLTELEAELNELRQKFEALEVELE 782

                          170       180       190
                   ....*....|....*....|....*....|....
gi 133903949  1493 DALESKEKAtglvgvqDSKHRDLEEQLDRANRER 1526
Cdd:pfam05911  783 EEKNCHEEL-------EAKCLELQEQLERNEKKE 809
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1386-1825 2.85e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 2.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1386 NADLSDALEKAKDELRQRNEKLADRQMVIERVERQLVHITEERNTIENRMTSQRQMyltneessrsreHEIRSMKARIST 1465
Cdd:COG4717    69 NLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKL------------LQLLPLYQELEA 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1466 LELHLREKESKLAHLRKEIEVLHgQLHDALESKEKAtglvgvQDSKHRDLEEQLDRANRERELAIgkqRRTLAENENLFR 1545
Cdd:COG4717   137 LEAELAELPERLEELEERLEELR-ELEEELEELEAE------LAELQEELEELLEQLSLATEEEL---QDLAEELEELQQ 206

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1546 KLEQLEKEREQLMREITDERRLNERNRTSLEELRVSERTWK--------SAMTTAKKPAEEQERAVQE------------ 1605
Cdd:COG4717   207 RLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEarlllliaAALLALLGLGGSLLSLILTiagvlflvlgll 286

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1606 QRRWEESNHEMTNRNTALTKECDRLRVEMRDQLNRMNGINLRSVDFERKNEELSSKLIVMQNTVTAMkkfeEEWKRLEAE 1685
Cdd:COG4717   287 ALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELL----REAEELEEE 362

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1686 MRAELKILRKEKLMQTAEIEDLK--RKSFRSDTEKKEIEGIRVRLEREISALKRhvDALEEEKGKTEKAVRETMNErraI 1763
Cdd:COG4717   363 LQLEELEQEIAALLAEAGVEDEEelRAALEQAEEYQELKEELEELEEQLEELLG--ELEELLEALDEEELEEELEE---L 437

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 133903949 1764 DKSLASMERENQQLYRNCAQLQAQIQNLERDagnRSVTKLAKEHSLLEARIAALIEEKRQLQ 1825
Cdd:COG4717   438 EEELEELEEELEELREELAELEAELEQLEED---GELAELLQELEELKAELRELAEEWAALK 496
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 864-1566 3.01e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 42.52  E-value: 3.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   864 EARMNELTKIHEMLMEEHDQLKVDHLHTEEEVERLKEKmrkeLEKLNEQNDGDRAEWSNERNRLE---SSKNEAVTELQE 940
Cdd:pfam12128  247 QQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQET----SAELNQLLRTLDDQWKEKRDELNgelSAADAAVAKDRS 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   941 RVQKLEDVVKEKEDKEI-----------ALRRDLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKT----LNEERMKL 1005
Cdd:pfam12128  323 ELEALEDQHGAFLDADIetaaadqeqlpSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRdiagIKDKLAKI 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1006 MEQKEEAMLVATKHATTIDQQTRrisvlegdvEKLTAGIAERESSINALESNTMELISKLETTEAELEKLKDelavmLKQ 1085
Cdd:pfam12128  403 REARDRQLAVAEDDLQALESELR---------EQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQ-----LEN 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1086 NSELKNGKEglsEKWNEERKKIQDLADQLREAnkvvhnmRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAaknev 1165
Cdd:pfam12128  469 FDERIERAR---EEQEAANAEVERLQSELRQA-------RKRRDQASEALRQASRRLEERQSALDELELQLFPQA----- 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1166 sGDLLRKMEHDA----QSMLKQAQNEQFRLTDLEKVRKALQ------------DENQRLVNDLATVKAAFEVKRETSKSA 1229
Cdd:pfam12128  534 -GTLLHFLRKEApdweQSIGKVISPELLHRTDLDPEVWDGSvggelnlygvklDLKRIDVPEWAASEEELRERLDKAEEA 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1230 ISDILDKYRSAEEK--ANKGELDNQRLRSDLATVTLKLERQELKakdsdnRLRDSQKRFE-EVQSKLANLQKSAVESLQN 1306
Cdd:pfam12128  613 LQSAREKQAAAEEQlvQANGELEKASREETFARTALKNARLDLR------RLFDEKQSEKdKKNKALAERKDSANERLNS 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1307 ---PMSSNSRQNRSIYVDIPRAASSIGLNENSDEVPLRSSPSVRFADSSQnmqrAVDSMDVSssvgvtlrfLKERIEQLE 1383
Cdd:pfam12128  687 leaQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKA----AIAARRSG---------AKAELKALE 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1384 ADNADLSDALEKAKDELRQRNEKLADRQMVIERVERQLVHITEERNTIENRMTSQRQMYLTNEESSRSREHEIRSMKARI 1463
Cdd:pfam12128  754 TWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARL 833

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1464 STlelhlrEKESKLAHLRKEIEVLHGQLHDALESkekatgLVGVQDSKHRDLEEQLDRANRERELAIGKqrrTLAENENL 1543
Cdd:pfam12128  834 IA------DTKLRRAKLEMERKASEKQQVRLSEN------LRGLRCEMSKLATLKEDANSEQAQGSIGE---RLAQLEDL 898

                          730       740
                   ....*....|....*....|....*..
gi 133903949  1544 FRKL----EQLEKEREQLMREITDERR 1566
Cdd:pfam12128  899 KLKRdylsESVKKYVEHFKNVIADHSG 925
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 435-737 3.07e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 42.73  E-value: 3.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  435 KRSSVYSQR-EHDLKKLDDELRKASEKIRNLEEQRESQEKLT-ISVQNSLNEAHRQ----HKQFIEELMIRHREELKERE 508
Cdd:PTZ00108  988 VRLDLYKKRkEYLLGKLERELARLSNKVRFIKHVINGELVITnAKKKDLVKELKKLgyvrFKDIIKKKSEKITAEEEEGA 1067

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  509 DSHEEALRSKDTEE-------------------RSRFEKERSEREKIRRESDELRETqrslkgDVAAM-KTDLDdkTLRL 568
Cdd:PTZ00108 1068 EEDDEADDEDDEEElgaavsydyllsmpiwsltKEKVEKLNAELEKKEKELEKLKNT------TPKDMwLEDLD--KFEE 1139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  569 DMLETERDELKKKLETEREQADQRD--LEIAECRAKLDEMAEKEAELRKEL-AEFQAIITAMEGEGKLNQEQFLESKNEL 645
Cdd:PTZ00108 1140 ALEEQEEVEEKEIAKEQRLKSKTKGkaSKLRKPKLKKKEKKKKKSSADKSKkASVVGNSKRVDSDEKRKLDDKPDNKKSN 1219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  646 NTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQltATYEEANGEIDILKAELTRLHEQVNERTRQISEA 725
Cdd:PTZ00108 1220 SSGSDQEDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDNDEFSSD--DLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESN 1297

                         330
                  ....*....|...
gi 133903949  726 -NEKYDDAARKND 737
Cdd:PTZ00108 1298 gGSKPSSPTKKKV 1310
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 292-473 3.22e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  292 AEQKNLDQKEQMKREKDDVLDETLRQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQ----NDELSDILEQLSKMA 367
Cdd:COG4942    24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAElaelEKEIAELRAELEAQK 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  368 HEMAG------GRGRNETPM-------------------DVARKMRKLLTTKNGEIDESREAAKQAEKERDRAKKDLEKE 422
Cdd:COG4942   104 EELAEllralyRLGRQPPLAlllspedfldavrrlqylkYLAPARREQAEELRADLAELAALRAELEAERAELEALLAEL 183

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 133903949  423 EKRRKDDREAERKRSSVYSQREHDLKKLDDELRKASEKIRNLEEQRESQEK 473
Cdd:COG4942   184 EEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 329-560 3.43e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 42.32  E-value: 3.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   329 EEKANERQRDLKRKEDECRK-----------LREQNDELSDILEQLSkmaheMAGGRGRNETPMDVARKMRKLLTTKNGE 397
Cdd:pfam05667  239 EYRKRKRTKLLKRIAEQLRSaalagteatsgASRSAQDLAELLSSFS-----GSSTTDTGLTKGSRFTHTEKLQFTNEAP 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   398 IDESREAAKQAEKERDRAKKDLEKEEKRRKDDReaerkRSSVYSQREHDLKKLDDELRKASEKIRNLEEQRESQEKLT-- 475
Cdd:pfam05667  314 AATSSPPTKVETEEELQQQREEELEELQEQLED-----LESSIQELEKEIKKLESSIKQVEEELEELKEQNEELEKQYkv 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   476 --------------ISVQNSLNEAHRQHKQFIEELMIRHREELKEREDSHEEALRSKDTEERSRFEKERSEREKIRRESD 541
Cdd:pfam05667  389 kkktldllpdaeenIAKLQALVDASAQRLVELAGQWEKHRVPLIEEYRALKEAKSNKEDESQRKLEEIKELREKIKEVAE 468

                          250       260
                   ....*....|....*....|..
gi 133903949   542 ELR---ETQRSLKGDVAAMKTD 560
Cdd:pfam05667  469 EAKqkeELYKQLVAEYERLPKD 490
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
582-794 3.63e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 3.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  582 LETEREQADQRDLEIAEcraKLDEMAEKEAELRKELAEFQAiitamegegklnQEQFLESKNELNTLTDQIESLNSEVEN 661
Cdd:COG3206   166 LELRREEARKALEFLEE---QLPELRKELEEAEAALEEFRQ------------KNGLVDLSEEAKLLLQQLSELESQLAE 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  662 KNEEIRNLMATLQEKEVHIQNVRTSSH---------QLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDA 732
Cdd:COG3206   231 ARAELAEAEARLAALRAQLGSGPDALPellqspviqQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQE 310

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 133903949  733 ARKNDALLE-DVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDL---RGNFDKLTNELKQ 794
Cdd:COG3206   311 AQRILASLEaELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVevaRELYESLLQRLEE 376
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 245-520 3.70e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.22  E-value: 3.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  245 KLISLWKEFTAVKRQLHELRTTTANDLDRQL-TEFTRCAT-LMRKAIRH-------AEQKNLDQKEQMKREKDDvLDETL 315
Cdd:PRK05771   10 LIVTLKSYKDEVLEALHELGVVHIEDLKEELsNERLRKLRsLLTKLSEAldklrsyLPKLNPLREEKKKVSVKS-LEELI 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  316 RqlnsvtenymKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQLSKMAHemaggrgrneTPMDVARKMR-KLLTTK 394
Cdd:PRK05771   89 K----------DVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEPWGN----------FDLDLSLLLGfKYVSVF 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  395 NGEIDESREAAKQAEKERDRAKKDLEKEE---------KRRKDDREAERKRSSVYSQREHDLKKLDDELRKASEKIRNLE 465
Cdd:PRK05771  149 VGTVPEDKLEELKLESDVENVEYISTDKGyvyvvvvvlKELSDEVEEELKKLGFERLELEEEGTPSELIREIKEELEEIE 228

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 133903949  466 EQRES-QEKLtisvqNSLNEAHRQHKQFIEELMirhrEELKEREDSHEEALRSKDT 520
Cdd:PRK05771  229 KERESlLEEL-----KELAKKYLEELLALYEYL----EIELERAEALSKFLKTDKT 275
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
181-695 3.82e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 42.33  E-value: 3.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  181 TLEEVNEMLREENDAALAANEHLRVDATNLSRQLQQlqqqqhtesmrfrsentryrnqtetqhrklisLWKEFTAVKRQL 260
Cdd:PRK02224  283 DLRERLEELEEERDDLLAEAGLDDADAEAVEARREE--------------------------------LEDRDEELRDRL 330

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  261 HELRTttandldrQLTEFTRCATLMRKAIRHAEQKNLDqkeqmKREKDDVLDETLRqlnsvtenymKSEEKANERQRDLK 340
Cdd:PRK02224  331 EECRV--------AAQAHNEEAESLREDADDLEERAEE-----LREEAAELESELE----------EAREAVEDRREEIE 387

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  341 RKEDECRKLREQ-----------NDELSDILEQLSKMAHEMAGGRGRNETPMDVARKMRKLLTTKN-------------- 395
Cdd:PRK02224  388 ELEEEIEELRERfgdapvdlgnaEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgqpvegsphv 467

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  396 GEIDESREAAKQAEKERDRAK---KDLEKEEKRRKDDREAERKRSSVYSQREHDLKKLDDELRKASEKIRNLEEQRESQE 472
Cdd:PRK02224  468 ETIEEDRERVEELEAELEDLEeevEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAA 547

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  473 KLtisvqNSLNEAHRQHKQFIEELMIRHREELKEREDSheealRSKDTEERSRFEKER---SEREKIRRESDELRETQRS 549
Cdd:PRK02224  548 EL-----EAEAEEKREAAAEAEEEAEEAREEVAELNSK-----LAELKERIESLERIRtllAAIADAEDEIERLREKREA 617

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  550 LkgdvAAMKTDLDDktlRLDMLETERDELKKKLETEREQADQRDLEIAEcrAKLDEMAEKEAELRKELAEFQAIITAMEG 629
Cdd:PRK02224  618 L----AELNDERRE---RLAEKRERKRELEAEFDEARIEEAREDKERAE--EYLEQVEEKLDELREERDDLQAEIGAVEN 688

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 133903949  630 EGKlNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEkevhiQNVRTSSHQLTATYE 695
Cdd:PRK02224  689 ELE-ELEELRERREALENRVEALEALYDEAEELESMYGDLRAELRQ-----RNVETLERMLNETFD 748
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 937-1167 3.86e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 3.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  937 ELQERVQKLEDVVKEKEDKEIALRRDLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEE--AML 1014
Cdd:COG4942    31 QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEElaELL 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1015 VAtkhATTIDQQTRRISVLEGDVeklTAGIAERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKE 1094
Cdd:COG4942   111 RA---LYRLGRQPPLALLLSPED---FLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELE 184

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 133903949 1095 GLSEKWNEERKKIQDLADQLREANKvvhnmrmknvNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSG 1167
Cdd:COG4942   185 EERAALEALKAERQKLLARLEKELA----------ELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 497-1088 3.97e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 42.12  E-value: 3.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   497 MIRHREELKERE--DSHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETE 574
Cdd:pfam10174  267 TEDREEEIKQMEvyKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQRAAILQTE 346

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   575 RDELKKKLEtEREQAdqrdleIAECRAKLDEMAEKEAELRKELAEFQAIITAMEgegklnqeqfleskNELNTLTDQIES 654
Cdd:pfam10174  347 VDALRLRLE-EKESF------LNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKE--------------RKINVLQKKIEN 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   655 LNSEVENKNEEIRNLMATLQEKEVHIQNVRTSshqltatyeeangeidilkaeLTRLHEQVNERTRQISEANEKYDdaaR 734
Cdd:pfam10174  406 LQEQLRDKDKQLAGLKERVKSLQTDSSNTDTA---------------------LTTLEEALSEKERIIERLKEQRE---R 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   735 KNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLN 814
Cdd:pfam10174  462 EDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLK 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   815 KSEkerkeellrmeelEQKNEAEMKEEYEVKLQLAEKDRQGVENFGKECEArmneltkihemlmeehdqlkvdhlhteeE 894
Cdd:pfam10174  542 KAH-------------NAEEAVRTNPEINDRIRLLEQEVARYKEESGKAQA----------------------------E 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   895 VERLKEKMRkelEKLNEQNDGDRaewsnERNRLESSKNEAVTELQERVQKLEDVVKEKEDKEIALRRDLEDSHEKSRDLD 974
Cdd:pfam10174  581 VERLLGILR---EVENEKNDKDK-----KIAELESLTLRQMKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNS 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   975 DKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEEAMLVATKHattiDQQTRRISVLEGDVEKLTAGIAERESSINAL 1054
Cdd:pfam10174  653 QQLQLEELMGALEKTRQELDATKARLSSTQQSLAEKDGHLTNLRA----ERRKQLEEILEMKQEALLAAISEKDANIALL 728

                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 133903949  1055 ESNTmeliSKLETTEAE---LEKLKDELAVMLKQNSE 1088
Cdd:pfam10174  729 ELSS----SKKKKTQEEvmaLKREKDRLVHQLKQQTQ 761
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 583-1314 4.08e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 42.13  E-value: 4.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   583 ETEREQADQRDLEIAECRAKLDEMAEkeaelRKELAEFQAIItamegegklnqEQFLESKNELNTLTDQIESLNSEVENK 662
Cdd:pfam12128  214 PKSRLNRQQVEHWIRDIQAIAGIMKI-----RPEFTKLQQEF-----------NTLESAELRLSHLHFGYKSDETLIASR 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   663 NEEIRNLMATLQEKevhiqnVRTSSHQLTATYEEANGEIDILKAELTRLHEQVnertrqisEANEkyDDAARKNDALLED 742
Cdd:pfam12128  278 QEERQETSAELNQL------LRTLDDQWKEKRDELNGELSAADAAVAKDRSEL--------EALE--DQHGAFLDADIET 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   743 VATWQEKYEQLKMELEEMNRRgqekereeadlralLDDLRGNFDKLTNELKQKGVTVDS-LNEEISSLKEQLNKSEKERK 821
Cdd:pfam12128  342 AAADQEQLPSWQSELENLEER--------------LKALTGKHQDVTAKYNRRRSKIKEqNNRDIAGIKDKLAKIREARD 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   822 EELLRMEELEQKNEAEMKEEYEVKLQLAEKDRQGVENFGKECEARMNELTKIHEMLME-EHDQLKVDHLHTEEEvERLKE 900
Cdd:pfam12128  408 RQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQlENFDERIERAREEQE-AANAE 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   901 KMRKELEKLNEQNDGDRAewsNERNRLEsskNEAVTELQERVQKLEDVVKEKEDKEIA-LRRDLEDSheksRDLDDKLRK 979
Cdd:pfam12128  487 VERLQSELRQARKRRDQA---SEALRQA---SRRLEERQSALDELELQLFPQAGTLLHfLRKEAPDW----EQSIGKVIS 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   980 MELTDEEKEEDRKKEQKTLNEERMKLMEQKEEAMLVATKHATTiDQQTRRISVLEGDVEKLTAGIAERESsinalesntm 1059
Cdd:pfam12128  557 PELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDVPEWAASE-EELRERLDKAEEALQSAREKQAAAEE---------- 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1060 elisKLETTEAELEKLKDELAVMLKQnseLKNGKEGLsEKWNEERKKIQDLADQLREANKVVHNMRMKNVNLEEKKNELD 1139
Cdd:pfam12128  626 ----QLVQANGELEKASREETFARTA---LKNARLDL-RRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKK 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1140 QNVTDLTNKVRQLEIQLMDKAAKNEVSGDL----------LRKMEHDAQSMLKQAQNEQFR-----------LTDLEKVR 1198
Cdd:pfam12128  698 HQAWLEEQKEQKREARTEKQAYWQVVEGALdaqlallkaaIAARRSGAKAELKALETWYKRdlaslgvdpdvIAKLKREI 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1199 KALQDENQRLVNDLATVKAAFEVKRETSKSAISDILDKYRSAEEKANKGELDNQRLRSDLATVTLKLERQELKAKDSDNR 1278
Cdd:pfam12128  778 RTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVR 857

                          730       740       750
                   ....*....|....*....|....*....|....*..
gi 133903949  1279 LRDSQKRFEEVQSKLANLQKSA-VESLQNPMSSNSRQ 1314
Cdd:pfam12128  858 LSENLRGLRCEMSKLATLKEDAnSEQAQGSIGERLAQ 894
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1461-1862 4.15e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.06  E-value: 4.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1461 ARISTLELHLREKESKLAHLRKEIEVLHgQLHDALESKEKATGLVGVQDSKHRDLEEQLDRANRERELaigkqRRTLAEN 1540
Cdd:COG4717    71 KELKELEEELKEAEEKEEEYAELQEELE-ELEEELEELEAELEELREELEKLEKLLQLLPLYQELEAL-----EAELAEL 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1541 ENLFRKLEQLEKEREQLMREITDERRLNERNRTSLEELRvsERTWKSAMTTAKKPAEEQERAVQEQRRWEESNHEMTNRN 1620
Cdd:COG4717   145 PERLEELEERLEELRELEEELEELEAELAELQEELEELL--EQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEEL 222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1621 TALTKECDRLRVEMRDQlnrmnginlrsvdferKNEELSSKLIVMQNTVTAMKKFEEEWKRLEAEMRAELKILRKEKLMQ 1700
Cdd:COG4717   223 EELEEELEQLENELEAA----------------ALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLL 286

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1701 TAEIEDLKRKSFRSDTEKKEIEGIRVRLEREISALKRHVDALEEEKGKTEKAVRETMNERRAIDKSLASMERENQQLYRN 1780
Cdd:COG4717   287 ALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLE 366

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1781 caQLQAQIQNLERDAGNRSVTKLAKEHSLLEARIAaLIEEKRQLQSMLDQKDANYSH-----KRKLLESQIQLLREQLEA 1855
Cdd:COG4717   367 --ELEQEIAALLAEAGVEDEEELRAALEQAEEYQE-LKEELEELEEQLEELLGELEEllealDEEELEEELEELEEELEE 443


                  ....*..
gi 133903949 1856 ERRKRTK 1862
Cdd:COG4717   444 LEEELEE 450
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
554-854 4.38e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.43  E-value: 4.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  554 VAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMegegkl 633
Cdd:COG4372    26 IAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQA------ 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  634 nQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHE 713
Cdd:COG4372   100 -QEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSE 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  714 QvnertrQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELK 793
Cdd:COG4372   179 A------EAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELL 252

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 133903949  794 QKGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEKDRQ 854
Cdd:COG4372   253 EEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGAL 313
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1372-1603 4.40e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 4.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1372 LRFLKERIEQLEADNADLSDALEKAKDELRQRNEKLADRQMVIERVERQLVHITEERNTIENRMTSQRQMYLTNEESSRS 1451
Cdd:COG4942    29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAE 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1452 REHEIRSMkARISTLELHLREKESKLAHLRKEievLHGQLHDALesKEKATGLVGVQdskhrdleEQLDRANRERELAIG 1531
Cdd:COG4942   109 LLRALYRL-GRQPPLALLLSPEDFLDAVRRLQ---YLKYLAPAR--REQAEELRADL--------AELAALRAELEAERA 174

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 133903949 1532 KQRRTLAENENLFRKLEQLEKEREQLMREITDERrlnERNRTSLEELRVSERTWKSAMTTAKKPAEEQERAV 1603
Cdd:COG4942   175 ELEALLAELEEERAALEALKAERQKLLARLEKEL---AELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1461-1579 4.97e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.77  E-value: 4.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1461 ARISTLELHLREKESKLAHLRKEIEVLHGQLHDaleskekatglvgvQDSKHRDLEEQLDRANRERELAIGKQRrtlaen 1540
Cdd:COG2433   406 RELTEEEEEIRRLEEQVERLEAEVEELEAELEE--------------KDERIERLERELSEARSEERREIRKDR------ 465

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 133903949 1541 enlfrKLEQLEKEREQLMREITDERRLNERNRTSLEELR 1579
Cdd:COG2433   466 -----EISRLDREIERLERELEEERERIEELKRKLERLK 499
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
329-598 5.19e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 5.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  329 EEKANERQRDLKRKEDECRKLREQNDELSDILEQLSKMAHEMAGGRGRNETPMDVA----------RKMRKLLTTKNG-- 396
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVAsaereiaeleAELERLDASSDDla 688

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  397 ----EIDESREAAKQAEKERDRAKKDLEKEEKRRKD-----DREAERKRSSVYSQREHDLKKLDDELRKA------SEKI 461
Cdd:COG4913   689 aleeQLEELEAELEELEEELDELKGEIGRLEKELEQaeeelDELQDRLEAAEDLARLELRALLEERFAAAlgdaveRELR 768

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  462 RNLEEQRESQEKLTISVQNSLNEAHRQHKQ--------------FIEELMIRHR----EELKEREDSHEEALRSKDTEER 523
Cdd:COG4913   769 ENLEERIDALRARLNRAEEELERAMRAFNRewpaetadldadleSLPEYLALLDrleeDGLPEYEERFKELLNENSIEFV 848

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 133903949  524 SRFEKE-RSEREKIRRESDELRETQRSLKGDvaamktdlDDKTLRLDMLETERDELK---KKLETEREQADQRDLEIAE 598
Cdd:COG4913   849 ADLLSKlRRAIREIKERIDPLNDSLKRIPFG--------PGRYLRLEARPRPDPEVRefrQELRAVTSGASLFDEELSE 919
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1684-1858 5.27e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 5.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1684 AEMRAELKILRKEKLMQTAEIEDLKRKSFRSDTEKKEIEGIRVRLEREISALKRHVDALEEEKGKTEKAVRETMNERRAI 1763
Cdd:COG4942    23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1764 DKSLASMERENQQLYRNCA-------------------------QLQAQIQNLERDAG--NRSVTKLAKEHSLLEARIAA 1816
Cdd:COG4942   103 KEELAELLRALYRLGRQPPlalllspedfldavrrlqylkylapARREQAEELRADLAelAALRAELEAERAELEALLAE 182

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 133903949 1817 LIEEKRQLQSMLDQKDANYSHKRKLLESQIQLLREQLEAERR 1858
Cdd:COG4942   183 LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 539-628 5.35e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.61  E-value: 5.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  539 ESDELRETQRSLKGDVAAMKTDLDDKTL-RLDMLETERDELKKKLETEREQADQRD---LEIAECRAKLDEMAEKEAELR 614
Cdd:COG0542   412 ELDELERRLEQLEIEKEALKKEQDEASFeRLAELRDELAELEEELEALKARWEAEKeliEEIQELKEELEQRYGKIPELE 491

                          90
                  ....*....|....
gi 133903949  615 KELAEFQAIITAME 628
Cdd:COG0542   492 KELAELEEELAELA 505
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 428-676 5.46e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 41.96  E-value: 5.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  428 DDREAERKRSSVYSQREHDLKKLDDELRKASEKirnleeqrESQEKLTISVQNSLNEAHRQHKQFIEELMIRHREELKER 507
Cdd:PRK10929   58 EERKGSLERAKQYQQVIDNFPKLSAELRQQLNN--------ERDEPRSVPPNMSTDALEQEILQVSSQLLEKSRQAQQEQ 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  508 EDSHEEA-----LRSKDTEERSRFEKERSEREKIRRESDELRETQR-SLKGDVAAMKTDLDDktLRLDMLETE-RDELKK 580
Cdd:PRK10929  130 DRAREISdslsqLPQQQTEARRQLNEIERRLQTLGTPNTPLAQAQLtALQAESAALKALVDE--LELAQLSANnRQELAR 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  581 -KLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAiitamEGEGKLNQ---EQF---LESKNELNTLT---D 650
Cdd:PRK10929  208 lRSELAKKRSQQLDAYLQALRNQLNSQRQREAERALESTELLA-----EQSGDLPKsivAQFkinRELSQALNQQAqrmD 282

                         250       260
                  ....*....|....*....|....*.
gi 133903949  651 QIESLNSEVENKNEEIRNLMATLQEK 676
Cdd:PRK10929  283 LIASQQRQAASQTLQVRQALNTLREQ 308
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1546-1799 6.66e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 6.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1546 KLEQLEKEREQLMREITDERRLNERNRTSLEELRVSERTWKSAMTTAKKPAEEQERAVQEQRRWEEsnhEMTNRNTALTK 1625
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELA---ELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1626 ECDRLRVEMRDQLNRMnginlrsvdfERKNEELSSKLIVMQNTVTAMKKFEEEWKRLEAEMRAELKILRKEKlmqtaeie 1705
Cdd:COG4942    98 ELEAQKEELAELLRAL----------YRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADL-------- 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949 1706 dlkrksfrsdtekKEIEGIRVRLEREISALKRHVDALEEEKGKTEKAVRETMNERRAIDKSLASMERENQQLYRNCAQLQ 1785
Cdd:COG4942   160 -------------AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELE 226

                         250
                  ....*....|....
gi 133903949 1786 AQIQNLERDAGNRS 1799
Cdd:COG4942   227 ALIARLEAEAAAAA 240
PRK12704 PRK12704
phosphodiesterase; Provisional
 803-956 6.69e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 6.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  803 NEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEeyevKLQLAEKDRQGVENFGKECEARMNELTKihemlmeehd 882
Cdd:PRK12704   63 KEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDR----KLELLEKREEELEKKEKELEQKQQELEK---------- 128

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 133903949  883 qlkvdhlhTEEEVERLKEKMRKELEKLneqndgdrAEWSNERNR---LESSKNEAVTELQERVQKLEDVVKEKEDKE 956
Cdd:PRK12704  129 --------KEEELEELIEEQLQELERI--------SGLTAEEAKeilLEKVEEEARHEAAVLIKEIEEEAKEEADKK 189
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1267-1859 7.04e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 41.26  E-value: 7.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1267 RQELKAKDSDNRLRDSQKRFEEVQS---KLANLQKSAVESLQNPMSSNS---RQNRSIYVDIPRAA-SSIGLNENSDEVP 1339
Cdd:pfam15921  135 RESQSQEDLRNQLQNTVHELEAAKClkeDMLEDSNTQIEQLRKMMLSHEgvlQEIRSILVDFEEASgKKIYEHDSMSTMH 214

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1340 LRSspsvrFADSSQNMQRAVDSmdvsssvgvTLRFLKERI----EQLEADNADLSDALEKAKDELRQRNEKLadrqmvIE 1415
Cdd:pfam15921  215 FRS-----LGSAISKILRELDT---------EISYLKGRIfpveDQLEALKSESQNKIELLLQQHQDRIEQL------IS 274

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1416 RVERQLVHITEERNTIENRMTS-QRQMYLTNEESSRSREHEIR---SMKARISTLELHLREK----ESKLAHLRKEIEVL 1487
Cdd:pfam15921  275 EHEVEITGLTEKASSARSQANSiQSQLEIIQEQARNQNSMYMRqlsDLESTVSQLRSELREAkrmyEDKIEELEKQLVLA 354

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1488 HGQLHDALESKEKATGLVGVQDSKHRDLEEQLDRanRERELAIGKQ-------------------RRTLAENENLFRKLE 1548
Cdd:pfam15921  355 NSELTEARTERDQFSQESGNLDDQLQKLLADLHK--REKELSLEKEqnkrlwdrdtgnsitidhlRRELDDRNMEVQRLE 432

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1549 QLEK--------EREQLMREITDERRLNERNRT---SLEELRVSERTWKSAMTTAKKPAEEQERAVQE-QRRWEESNHEM 1616
Cdd:pfam15921  433 ALLKamksecqgQMERQMAAIQGKNESLEKVSSltaQLESTKEMLRKVVEELTAKKMTLESSERTVSDlTASLQEKERAI 512

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1617 TNRNTALTKECDRLRVEMRD-QLNRMNGINLRSVDFErkNEELSSKLIVMQNTVTAMKKFEEEWKRLEAEMRAELKILRK 1695
Cdd:pfam15921  513 EATNAEITKLRSRVDLKLQElQHLKNEGDHLRNVQTE--CEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQV 590

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1696 EKLMQTAEIEDLKrksfrsdTEKKEIEGIRVRLEREISALKRHVDALEEEKGKTEKAVRETMNERRAIDKSLASMERENQ 1775
Cdd:pfam15921  591 EKAQLEKEINDRR-------LELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVK 663

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1776 QLYRNCAQLQAQIQNLERDAGNRSvTKLAKEHSLLEARIAALIEEKRQLQSMLDQKDANYSHKRKL---LESQIQLLREQ 1852
Cdd:pfam15921  664 TSRNELNSLSEDYEVLKRNFRNKS-EEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVamgMQKQITAKRGQ 742


                   ....*..
gi 133903949  1853 LEAERRK 1859
Cdd:pfam15921  743 IDALQSK 749
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 766-1164 7.09e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 41.25  E-value: 7.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   766 EKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEisslKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVK 845
Cdd:pfam05483  251 EKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEK----KDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTI 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   846 LQLAEKDRQGVENFGKECEARMNELTKIHEMLMEEHDQLKVDHLHTEEEVERLK------EKMRKELEKLNEQNDGDRAE 919
Cdd:pfam05483  327 CQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKiitmelQKKSSELEEMTKFKNNKEVE 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   920 WSNERNRLesSKNEAVTELQERVQKLEDVVKEKEDKEIALrrdLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLN 999
Cdd:pfam05483  407 LEELKKIL--AEDEKLLDEKKQFEKIAEELKGKEQELIFL---LQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELE 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1000 EERMKLMEQKEEAMLVATKHATTIDQQTRRISVLEGDVEKLTAGIAERE---SSINALESNTMELISKLETTEAELEKLK 1076
Cdd:pfam05483  482 KEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEErmlKQIENLEEKEMNLRDELESVREEFIQKG 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  1077 DELAVMLKQNSELKNGKEGLSEKWNEERK----KIQDLADQLREANKVVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQL 1152
Cdd:pfam05483  562 DEVKCKLDKSEENARSIEYEVLKKEKQMKilenKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKL 641

                          410
                   ....*....|..
gi 133903949  1153 EIQLMDKAAKNE 1164
Cdd:pfam05483  642 ELELASAKQKFE 653
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 573-864 7.58e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.26  E-value: 7.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   573 TERDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIIT-----AMEGEGKLNQEQFLESKNELNT 647
Cdd:pfam17380  285 SERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAeqermAMERERELERIRQEERKRELER 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   648 LTDqiESLNSEVEnKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLH-EQVNERTRQISEAN 726
Cdd:pfam17380  365 IRQ--EEIAMEIS-RMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRaEQEEARQREVRRLE 441

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949   727 EkydDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEI 806
Cdd:pfam17380  442 E---ERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLL 518

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 133903949   807 SSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEKDRQGVENFGKECE 864
Cdd:pfam17380  519 EKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMERERE 576
PHA02896 PHA02896
A-type inclusion like protein; Provisional
 411-592 7.77e-03

A-type inclusion like protein; Provisional


Pssm-ID: 165222  Cd Length: 616  Bit Score: 41.17  E-value: 7.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  411 ERDRAKKDLEKEEKRRKDDREAERKRSSVYSQREHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQN---SLNEAHR 487
Cdd:PHA02896  423 QMDDKYDKRDHRYKNNKYDIYDDESPRYKYKDDDYDDNDDNDDDHIIPKKANNLEDAKDFEDEMMDAIADddyTPKSIRN 502

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 133903949  488 QHKQFIEElmirhREELKEREDSHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQR--------SLKGDVAAMKT 559
Cdd:PHA02896  503 RRNGYLLK-----DEDRYYYDRGHRNLGAEKDPEKPHPDKDEEYPEDKDKSDDDRLNDADKamrkleadGFGDRYRKIKE 577

                         170       180       190
                  ....*....|....*....|....*....|...
gi 133903949  560 DLDDKTLRLDMLETERDELKKKLETEREQADQR 592
Cdd:PHA02896  578 KMDNLEDDYDDLRKHAIELPKKLDNQSGNGDRD 610
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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